# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TRM13.hmm.txt # target sequence database: proteomes/Strongylocentrotus_purpuratus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TRM13 [M=262] Accession: PF05206.13 Description: Methyltransferase TRM13 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-78 264.1 0.4 3.6e-35 122.4 0.0 3.2 3 tr|W4ZD26|W4ZD26_STRPU Uncharacterized protein OS=Strongyloc 7.9e-77 259.0 0.7 1.5e-37 130.2 0.5 3.2 2 tr|W4ZJ10|W4ZJ10_STRPU Uncharacterized protein OS=Strongyloc 5.3e-05 23.6 0.3 0.0052 17.0 0.1 2.6 2 tr|W4ZJM6|W4ZJM6_STRPU Uncharacterized protein OS=Strongyloc ------ inclusion threshold ------ 0.11 12.6 3.5 0.13 12.4 3.5 1.1 1 tr|W4YHC2|W4YHC2_STRPU Uncharacterized protein OS=Strongyloc 0.24 11.5 0.0 0.39 10.9 0.0 1.2 1 tr|W4YSH5|W4YSH5_STRPU Uncharacterized protein OS=Strongyloc Domain annotation for each sequence (and alignments): >> tr|W4ZD26|W4ZD26_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 122.4 0.0 6.3e-39 3.6e-35 2 131 .. 157 284 .. 156 291 .. 0.91 2 ! 77.3 0.1 3.7e-25 2.1e-21 126 214 .. 388 473 .. 366 484 .. 0.82 3 ! 61.1 0.0 3.2e-20 1.8e-16 183 262 .] 492 573 .. 478 573 .. 0.76 Alignments for each domain: == domain 1 score: 122.4 bits; conditional E-value: 6.3e-39 TRM13 2 qqsslignleelkllekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnls 88 q sl+g++++l+ll++++++vEfGaG+g+ls++++qa+ + e+++++L+dra r+k D+ ++d+ ++R+ +dI++L l tr|W4ZD26|W4ZD26_STRPU 157 QLDSLLGHMNRLDLLQPDTCFVEFGAGRGRLSQWIQQAMGN--LEQTSFLLVDRAAVRHKRDTFYQRDDG--GYERISMDIENLILG 239 778************************************54..59************************7..9************** PP TRM13 89 aleele..kkkkvvavsKHLCGaATDLtLrcllnsekaskkakle 131 +++++ +++vva KHLCGaATDL+Lrcl+++++ + + + tr|W4ZD26|W4ZD26_STRPU 240 KVPNVCnhGNRPVVAYTKHLCGAATDLALRCLMETRTGNIPQASS 284 ***98778999***********************99876655555 PP == domain 2 score: 77.3 bits; conditional E-value: 3.7e-25 TRM13 126 kkakleglliAlCChhvCswkeyvnkeyleelgitkeefqiltkmvSWavsgkrkseaeeedekeekekeekkeeeeseeekkskls 212 ++ ++g+++AlCChh+Csw++ v+k+++++ gi++++f +l++m+SWa++g+r +++ k+e++keek +e++++ +k+++l+ tr|W4ZD26|W4ZD26_STRPU 388 TTIPVKGVVMALCCHHRCSWRTHVGKQFFQDVGISERDFMALVRMSSWATCGTR---LAKDGDKDENKKEEKGKEDGKDGKKMEGLT 471 36789*************************************************...455555667777777777788888888887 PP TRM13 213 se 214 tr|W4ZD26|W4ZD26_STRPU 472 DD 473 55 PP == domain 3 score: 61.1 bits; conditional E-value: 3.2e-20 TRM13 183 aeeedekeekekeekkeeeeseee..kksklsseereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLlak 262 +e++++ +e+ + e+++ e++++ +ls+ ereeiG+k+kr++d+gR+ +l++ g++a+lv Yve+++s+Env+L+ak tr|W4ZD26|W4ZD26_STRPU 492 MERSKKGKERVEGENSDIPEEQASvvGSLGLSVPEREEIGFKCKRILDMGRIIYLRNLGLDAKLVSYVERNISPENVVLIAK 573 3444444455555554444444440045689************************************************985 PP >> tr|W4ZJ10|W4ZJ10_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 122.3 0.0 6.7e-39 3.8e-35 2 126 .. 42 164 .. 41 203 .. 0.93 2 ! 130.2 0.5 2.7e-41 1.5e-37 126 262 .] 304 489 .. 287 489 .. 0.87 Alignments for each domain: == domain 1 score: 122.3 bits; conditional E-value: 6.7e-39 TRM13 2 qqsslignleelkllekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnls 88 q sl+g++++l+ll++++++vEfGaG+g+ls++++qa+ + e+++++L+dra r+k D+ ++d+ ++R+ +dI++L l tr|W4ZJ10|W4ZJ10_STRPU 42 QLDSLLGHMNRLDLLQPDTCFVEFGAGRGRLSQWIQQAMG--SLEQTSFLLVDRAAVRHKRDTFYQRDDG--GYERISMDIENLILG 124 778************************************5..4699***********************7..9************** PP TRM13 89 aleele..kkkkvvavsKHLCGaATDLtLrcllnsekask 126 +++++ +++vva KHLCGaATDL+Lrcl+++++ ++ tr|W4ZJ10|W4ZJ10_STRPU 125 KVPNVCnhGNRPVVAYTKHLCGAATDLALRCLMETRTGNE 164 ***98778999**********************9988754 PP == domain 2 score: 130.2 bits; conditional E-value: 2.7e-41 TRM13 126 kkakleglliAlCChhvCswkeyvnkeyleelgitkeefqiltkmvSWavsgkrkse.............................. 182 ++ ++g+++AlCChh+Csw++ v+k+++++ gi+++ef +l++m+SWa++g+r + tr|W4ZJ10|W4ZJ10_STRPU 304 TNIPVKGVVMALCCHHRCSWRTHVGKQFFQDVGISDREFMALVRMSSWATCGTRLVKdggkdqnkkevkgkadekdgvkverltddk 390 46789*************************************************87799**************************** PP TRM13 183 ...................aeeedekeekekeekkeeeeseeekksklsseereeiGlkakrlidegRllalkekgfeaelvkYvek 250 +++ +++ + ++++ +ee+++ +ls+ ereeiG+k+kr++d++R+ +l++ g++a+lv Yve+ tr|W4ZJ10|W4ZJ10_STRPU 391 deggiketqkgagteelveRNKKGKESLEGENSDIHEEQASVVSSLGLSVPEREEIGFKCKRILDMARIVYLRNLGLDAKLVAYVER 477 *************999864333333333334444455555555666899************************************** PP TRM13 251 evslEnvlLlak 262 ++s+Env+L+ak tr|W4ZJ10|W4ZJ10_STRPU 478 NISPENVVLIAK 489 *********985 PP >> tr|W4ZJM6|W4ZJM6_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.1 9.1e-07 0.0052 73 165 .. 780 873 .. 771 890 .. 0.76 2 ! 3.8 0.0 0.0095 55 218 260 .. 892 934 .. 887 936 .. 0.93 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 9.1e-07 TRM13 73 laikRlkidIkdLnlsaleelekkkkv......vavsKHLCGaATDLtLrcllnsekaskkakleglliAlCCh...hvCswkeyvn 150 +kR ++ L l++++ ++ + ++vs H CG+ATD+ L ++++ ++ ++ CC h ++ +y tr|W4ZJM6|W4ZJM6_STRPU 780 ESLKRALGRVQTLGLQNVTLYLSNIDYfygqfdIGVSLHACGVATDIVLSKCVEQGAS--------FVSSPCCYgslHNTHHLTYPR 858 4778888888888888887744444445677779***************999988774........677888864458888888888 PP TRM13 151 keyleelgitkeefq 165 +++++e++i+k+++ tr|W4ZJM6|W4ZJM6_STRPU 859 SKVFRESNISKKNYF 873 999999999998554 PP == domain 2 score: 3.8 bits; conditional E-value: 0.0095 TRM13 218 eiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLl 260 + G+++ id R++ +e g+++ + +++ s+ n lL+ tr|W4ZJM6|W4ZJM6_STRPU 892 KQGKRCMGYIDRDRAELAREYGYHVTICSLKPETCSPKNNLLI 934 66999***********************************998 PP >> tr|W4YHC2|W4YHC2_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 3.5 2.2e-05 0.13 157 207 .. 54 104 .. 40 106 .] 0.69 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 2.2e-05 TRM13 157 lgitke.efqiltkmvSWavsgkrkseaeeedekeekekeekkeeeeseeek 207 ++i+++ f+ ++ W ++g++k+ ++++++kee+e+ee++eeee+ee k tr|W4YHC2|W4YHC2_STRPU 54 TDIKQRsTFHDMQIKIGWILEGSNKKMKKKKKTKEEEEEEEEEEEEEEEE-K 104 57788779****************77666655555555544444444333.3 PP >> tr|W4YSH5|W4YSH5_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 6.8e-05 0.39 133 183 .. 225 289 .. 213 315 .. 0.76 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 6.8e-05 TRM13 133 lliAlCChhv.Cswkeyvn....keyleelgitkeefqiltkmvSWavsgkrkse.........a 183 + +A+CC + +s+ +++ ++l e+g ++++++i++k+ SW +g + s+ + tr|W4YSH5|W4YSH5_STRPU 225 IFVAVCCIPAaSSVLTFLLmpesPKFLLEQGNEEKSLEIMKKIYSWNHKGVKASDypidylvpsS 289 789****866155667776788899**********************999997777776654321 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (262 nodes) Target sequences: 28594 (14266044 residues searched) Passed MSV filter: 2291 (0.0801217); expected 571.9 (0.02) Passed bias filter: 904 (0.031615); expected 571.9 (0.02) Passed Vit filter: 107 (0.00374204); expected 28.6 (0.001) Passed Fwd filter: 15 (0.000524586); expected 0.3 (1e-05) Initial search space (Z): 28594 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.45u 0.01s 00:00:00.46 Elapsed: 00:00:00.15 # Mc/sec: 24918.02 // [ok]