# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TRM13.hmm.txt
# target sequence database:        proteomes/Strongylocentrotus_purpuratus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TRM13  [M=262]
Accession:   PF05206.13
Description: Methyltransferase TRM13
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    2.1e-78  264.1   0.4    3.6e-35  122.4   0.0    3.2  3  tr|W4ZD26|W4ZD26_STRPU  Uncharacterized protein OS=Strongyloc
    7.9e-77  259.0   0.7    1.5e-37  130.2   0.5    3.2  2  tr|W4ZJ10|W4ZJ10_STRPU  Uncharacterized protein OS=Strongyloc
    5.3e-05   23.6   0.3     0.0052   17.0   0.1    2.6  2  tr|W4ZJM6|W4ZJM6_STRPU  Uncharacterized protein OS=Strongyloc
  ------ inclusion threshold ------
       0.11   12.6   3.5       0.13   12.4   3.5    1.1  1  tr|W4YHC2|W4YHC2_STRPU  Uncharacterized protein OS=Strongyloc
       0.24   11.5   0.0       0.39   10.9   0.0    1.2  1  tr|W4YSH5|W4YSH5_STRPU  Uncharacterized protein OS=Strongyloc


Domain annotation for each sequence (and alignments):
>> tr|W4ZD26|W4ZD26_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.4   0.0   6.3e-39   3.6e-35       2     131 ..     157     284 ..     156     291 .. 0.91
   2 !   77.3   0.1   3.7e-25   2.1e-21     126     214 ..     388     473 ..     366     484 .. 0.82
   3 !   61.1   0.0   3.2e-20   1.8e-16     183     262 .]     492     573 ..     478     573 .. 0.76

  Alignments for each domain:
  == domain 1  score: 122.4 bits;  conditional E-value: 6.3e-39
                   TRM13   2 qqsslignleelkllekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnls 88 
                             q  sl+g++++l+ll++++++vEfGaG+g+ls++++qa+ +   e+++++L+dra  r+k D+  ++d+    ++R+ +dI++L l 
  tr|W4ZD26|W4ZD26_STRPU 157 QLDSLLGHMNRLDLLQPDTCFVEFGAGRGRLSQWIQQAMGN--LEQTSFLLVDRAAVRHKRDTFYQRDDG--GYERISMDIENLILG 239
                             778************************************54..59************************7..9************** PP

                   TRM13  89 aleele..kkkkvvavsKHLCGaATDLtLrcllnsekaskkakle 131
                             +++++    +++vva  KHLCGaATDL+Lrcl+++++ +  +  +
  tr|W4ZD26|W4ZD26_STRPU 240 KVPNVCnhGNRPVVAYTKHLCGAATDLALRCLMETRTGNIPQASS 284
                             ***98778999***********************99876655555 PP

  == domain 2  score: 77.3 bits;  conditional E-value: 3.7e-25
                   TRM13 126 kkakleglliAlCChhvCswkeyvnkeyleelgitkeefqiltkmvSWavsgkrkseaeeedekeekekeekkeeeeseeekkskls 212
                             ++  ++g+++AlCChh+Csw++ v+k+++++ gi++++f +l++m+SWa++g+r    +++  k+e++keek +e++++ +k+++l+
  tr|W4ZD26|W4ZD26_STRPU 388 TTIPVKGVVMALCCHHRCSWRTHVGKQFFQDVGISERDFMALVRMSSWATCGTR---LAKDGDKDENKKEEKGKEDGKDGKKMEGLT 471
                             36789*************************************************...455555667777777777788888888887 PP

                   TRM13 213 se 214
                               
  tr|W4ZD26|W4ZD26_STRPU 472 DD 473
                             55 PP

  == domain 3  score: 61.1 bits;  conditional E-value: 3.2e-20
                   TRM13 183 aeeedekeekekeekkeeeeseee..kksklsseereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLlak 262
                             +e++++ +e+ + e+++  e++++     +ls+ ereeiG+k+kr++d+gR+ +l++ g++a+lv Yve+++s+Env+L+ak
  tr|W4ZD26|W4ZD26_STRPU 492 MERSKKGKERVEGENSDIPEEQASvvGSLGLSVPEREEIGFKCKRILDMGRIIYLRNLGLDAKLVSYVERNISPENVVLIAK 573
                             3444444455555554444444440045689************************************************985 PP

>> tr|W4ZJ10|W4ZJ10_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.3   0.0   6.7e-39   3.8e-35       2     126 ..      42     164 ..      41     203 .. 0.93
   2 !  130.2   0.5   2.7e-41   1.5e-37     126     262 .]     304     489 ..     287     489 .. 0.87

  Alignments for each domain:
  == domain 1  score: 122.3 bits;  conditional E-value: 6.7e-39
                   TRM13   2 qqsslignleelkllekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnls 88 
                             q  sl+g++++l+ll++++++vEfGaG+g+ls++++qa+   + e+++++L+dra  r+k D+  ++d+    ++R+ +dI++L l 
  tr|W4ZJ10|W4ZJ10_STRPU  42 QLDSLLGHMNRLDLLQPDTCFVEFGAGRGRLSQWIQQAMG--SLEQTSFLLVDRAAVRHKRDTFYQRDDG--GYERISMDIENLILG 124
                             778************************************5..4699***********************7..9************** PP

                   TRM13  89 aleele..kkkkvvavsKHLCGaATDLtLrcllnsekask 126
                             +++++    +++vva  KHLCGaATDL+Lrcl+++++ ++
  tr|W4ZJ10|W4ZJ10_STRPU 125 KVPNVCnhGNRPVVAYTKHLCGAATDLALRCLMETRTGNE 164
                             ***98778999**********************9988754 PP

  == domain 2  score: 130.2 bits;  conditional E-value: 2.7e-41
                   TRM13 126 kkakleglliAlCChhvCswkeyvnkeyleelgitkeefqiltkmvSWavsgkrkse.............................. 182
                             ++  ++g+++AlCChh+Csw++ v+k+++++ gi+++ef +l++m+SWa++g+r  +                              
  tr|W4ZJ10|W4ZJ10_STRPU 304 TNIPVKGVVMALCCHHRCSWRTHVGKQFFQDVGISDREFMALVRMSSWATCGTRLVKdggkdqnkkevkgkadekdgvkverltddk 390
                             46789*************************************************87799**************************** PP

                   TRM13 183 ...................aeeedekeekekeekkeeeeseeekksklsseereeiGlkakrlidegRllalkekgfeaelvkYvek 250
                                                 +++ +++ + ++++ +ee+++     +ls+ ereeiG+k+kr++d++R+ +l++ g++a+lv Yve+
  tr|W4ZJ10|W4ZJ10_STRPU 391 deggiketqkgagteelveRNKKGKESLEGENSDIHEEQASVVSSLGLSVPEREEIGFKCKRILDMARIVYLRNLGLDAKLVAYVER 477
                             *************999864333333333334444455555555666899************************************** PP

                   TRM13 251 evslEnvlLlak 262
                             ++s+Env+L+ak
  tr|W4ZJ10|W4ZJ10_STRPU 478 NISPENVVLIAK 489
                             *********985 PP

>> tr|W4ZJM6|W4ZJM6_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.1   9.1e-07    0.0052      73     165 ..     780     873 ..     771     890 .. 0.76
   2 !    3.8   0.0    0.0095        55     218     260 ..     892     934 ..     887     936 .. 0.93

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 9.1e-07
                   TRM13  73 laikRlkidIkdLnlsaleelekkkkv......vavsKHLCGaATDLtLrcllnsekaskkakleglliAlCCh...hvCswkeyvn 150
                               +kR    ++ L l++++   ++  +      ++vs H CG+ATD+ L  ++++ ++        ++   CC    h  ++ +y  
  tr|W4ZJM6|W4ZJM6_STRPU 780 ESLKRALGRVQTLGLQNVTLYLSNIDYfygqfdIGVSLHACGVATDIVLSKCVEQGAS--------FVSSPCCYgslHNTHHLTYPR 858
                             4778888888888888887744444445677779***************999988774........677888864458888888888 PP

                   TRM13 151 keyleelgitkeefq 165
                             +++++e++i+k+++ 
  tr|W4ZJM6|W4ZJM6_STRPU 859 SKVFRESNISKKNYF 873
                             999999999998554 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.0095
                   TRM13 218 eiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLl 260
                             + G+++   id  R++  +e g+++ +    +++ s+ n lL+
  tr|W4ZJM6|W4ZJM6_STRPU 892 KQGKRCMGYIDRDRAELAREYGYHVTICSLKPETCSPKNNLLI 934
                             66999***********************************998 PP

>> tr|W4YHC2|W4YHC2_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   3.5   2.2e-05      0.13     157     207 ..      54     104 ..      40     106 .] 0.69

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.2e-05
                   TRM13 157 lgitke.efqiltkmvSWavsgkrkseaeeedekeekekeekkeeeeseeek 207
                             ++i+++  f+ ++    W ++g++k+ ++++++kee+e+ee++eeee+ee k
  tr|W4YHC2|W4YHC2_STRPU  54 TDIKQRsTFHDMQIKIGWILEGSNKKMKKKKKTKEEEEEEEEEEEEEEEE-K 104
                             57788779****************77666655555555544444444333.3 PP

>> tr|W4YSH5|W4YSH5_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   6.8e-05      0.39     133     183 ..     225     289 ..     213     315 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 6.8e-05
                   TRM13 133 lliAlCChhv.Cswkeyvn....keyleelgitkeefqiltkmvSWavsgkrkse.........a 183
                             + +A+CC  + +s+ +++      ++l e+g ++++++i++k+ SW  +g + s+         +
  tr|W4YSH5|W4YSH5_STRPU 225 IFVAVCCIPAaSSVLTFLLmpesPKFLLEQGNEEKSLEIMKKIYSWNHKGVKASDypidylvpsS 289
                             789****866155667776788899**********************999997777776654321 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (262 nodes)
Target sequences:                        28594  (14266044 residues searched)
Passed MSV filter:                      2291  (0.0801217); expected 571.9 (0.02)
Passed bias filter:                      904  (0.031615); expected 571.9 (0.02)
Passed Vit filter:                       107  (0.00374204); expected 28.6 (0.001)
Passed Fwd filter:                        15  (0.000524586); expected 0.3 (1e-05)
Initial search space (Z):              28594  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.45u 0.01s 00:00:00.46 Elapsed: 00:00:00.15
# Mc/sec: 24918.02
//
[ok]