# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TRM13.hmm.txt
# target sequence database:        proteomes/Tetrahymena_thermophila.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TRM13  [M=262]
Accession:   PF05206.13
Description: Methyltransferase TRM13
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    5.6e-71  239.7  24.2    3.6e-66  223.9   9.9    3.3  3  tr|Q236Z5|Q236Z5_TETTS  Methyltransferase TRM13 protein OS=Te


Domain annotation for each sequence (and alignments):
>> tr|Q236Z5|Q236Z5_TETTS  Methyltransferase TRM13 protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   1.0     0.054   1.5e+03     162     217 ..      30      82 ..      13      88 .. 0.53
   2 !   25.5   0.5   4.7e-10   1.3e-05       4      59 ..     241     297 ..     238     330 .. 0.73
   3 !  223.9   9.9   1.3e-70   3.6e-66      32     262 .]     328     587 .]     298     587 .] 0.91

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.054
                   TRM13 162 e.efqiltkmvSWavsgkrkseaeeedekeekekeekkeeeeseeekksklsseere 217
                             +  f  + ++  +  + ++ +e+++  e+++++k ++    +++e+++++l+s+  +
  tr|Q236Z5|Q236Z5_TETTS  30 KnRFCKFECLEGFDYCHHHAHENARFLEEDTNSKFQE----SNNEQNVEQLKSNITA 82 
                             4466666666666777777555444444444444444....4444444444444443 PP

  == domain 2  score: 25.5 bits;  conditional E-value: 4.7e-10
                   TRM13   4 sslignleelkllekssayvEfGaGkgelsryvnqaleed.kkenskyvLidrasnr 59 
                               l++ ++++++++++ +y+EfGaGkg ls+ ++++l+   ++e ++ vL++ +++ 
  tr|Q236Z5|Q236Z5_TETTS 241 CKLVEVMKQQGIWNNQYIYIEFGAGKGLLSHGIAKSLQLGeNSELTCEVLMESMKEN 297
                             56999******************************9987745666777787766554 PP

  == domain 3  score: 223.9 bits;  conditional E-value: 1.3e-70
                   TRM13  32 lsryvnq..aleed....kkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnlsaleele..kkkkv.......vavs 103
                             +++++nq   ++ed    k +++++vL++ +s+r+k+Dr +r++     + R++++I d+n++al+++   +k+++       v+vs
  tr|Q236Z5|Q236Z5_TETTS 328 MDQEQNQkdDIQEDqpsyKPYHACHVLLELESRRNKMDRLHRDNP---FYLRYRTNILDFNVNALHQILleQKYPYinqdlrvVGVS 411
                             55555554466666899999**********************999...9*****************97655666668888888**** PP

                   TRM13 104 KHLCGaATDLtLrcllnsekaskkakleglliAlCChhvCswkeyvnkey.leelgitkeefqiltkmvSWavsgkrkse....... 182
                             KH+CG ATDL++++lln+++    +k+eg++iA+CChh+Cs+++y+n+e+ ++elg+t+e++qil++++SW+vsg+ k+e       
  tr|Q236Z5|Q236Z5_TETTS 412 KHMCGGATDLSINTLLNCQNP---QKFEGMMIATCCHHRCSPDTYTNNEFlMNELGYTSEDLQILFYCSSWYVSGQIKEEimkkieq 495
                             *******************95...69************************77899**********************999******* PP

                   TRM13 183 ............aeeedekeekekeekkeeeeseeekksklsseereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnv 257
                                         +++e+++++k++e+kk+ e+s+ ++k++lsse+++ iG+++kr++d+gR+l+l +kg++ ++vkY++  +s+En+
  tr|Q236Z5|Q236Z5_TETTS 496 seqkqvseqlnqIQNENSQDNKQEESKKVIEQSQPNNKEWLSSEKKSLIGKMVKRTVDIGRILNLVKKGKKGRIVKYCDFILSPENF 582
                             ***********9999999********************************************************************* PP

                   TRM13 258 lLlak 262
                             +++ak
  tr|Q236Z5|Q236Z5_TETTS 583 VIIAK 587
                             **985 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (262 nodes)
Target sequences:                        26971  (16912921 residues searched)
Passed MSV filter:                      6886  (0.255311); expected 539.4 (0.02)
Passed bias filter:                      475  (0.0176115); expected 539.4 (0.02)
Passed Vit filter:                        35  (0.00129769); expected 27.0 (0.001)
Passed Fwd filter:                         3  (0.000111231); expected 0.3 (1e-05)
Initial search space (Z):              26971  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.02s 00:00:00.55 Elapsed: 00:00:00.16
# Mc/sec: 27694.91
//
[ok]