# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TRM13.hmm.txt # target sequence database: proteomes/Tetrahymena_thermophila.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TRM13 [M=262] Accession: PF05206.13 Description: Methyltransferase TRM13 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-71 239.7 24.2 3.6e-66 223.9 9.9 3.3 3 tr|Q236Z5|Q236Z5_TETTS Methyltransferase TRM13 protein OS=Te Domain annotation for each sequence (and alignments): >> tr|Q236Z5|Q236Z5_TETTS Methyltransferase TRM13 protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 1.0 0.054 1.5e+03 162 217 .. 30 82 .. 13 88 .. 0.53 2 ! 25.5 0.5 4.7e-10 1.3e-05 4 59 .. 241 297 .. 238 330 .. 0.73 3 ! 223.9 9.9 1.3e-70 3.6e-66 32 262 .] 328 587 .] 298 587 .] 0.91 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.054 TRM13 162 e.efqiltkmvSWavsgkrkseaeeedekeekekeekkeeeeseeekksklsseere 217 + f + ++ + + ++ +e+++ e+++++k ++ +++e+++++l+s+ + tr|Q236Z5|Q236Z5_TETTS 30 KnRFCKFECLEGFDYCHHHAHENARFLEEDTNSKFQE----SNNEQNVEQLKSNITA 82 4466666666666777777555444444444444444....4444444444444443 PP == domain 2 score: 25.5 bits; conditional E-value: 4.7e-10 TRM13 4 sslignleelkllekssayvEfGaGkgelsryvnqaleed.kkenskyvLidrasnr 59 l++ ++++++++++ +y+EfGaGkg ls+ ++++l+ ++e ++ vL++ +++ tr|Q236Z5|Q236Z5_TETTS 241 CKLVEVMKQQGIWNNQYIYIEFGAGKGLLSHGIAKSLQLGeNSELTCEVLMESMKEN 297 56999******************************9987745666777787766554 PP == domain 3 score: 223.9 bits; conditional E-value: 1.3e-70 TRM13 32 lsryvnq..aleed....kkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnlsaleele..kkkkv.......vavs 103 +++++nq ++ed k +++++vL++ +s+r+k+Dr +r++ + R++++I d+n++al+++ +k+++ v+vs tr|Q236Z5|Q236Z5_TETTS 328 MDQEQNQkdDIQEDqpsyKPYHACHVLLELESRRNKMDRLHRDNP---FYLRYRTNILDFNVNALHQILleQKYPYinqdlrvVGVS 411 55555554466666899999**********************999...9*****************97655666668888888**** PP TRM13 104 KHLCGaATDLtLrcllnsekaskkakleglliAlCChhvCswkeyvnkey.leelgitkeefqiltkmvSWavsgkrkse....... 182 KH+CG ATDL++++lln+++ +k+eg++iA+CChh+Cs+++y+n+e+ ++elg+t+e++qil++++SW+vsg+ k+e tr|Q236Z5|Q236Z5_TETTS 412 KHMCGGATDLSINTLLNCQNP---QKFEGMMIATCCHHRCSPDTYTNNEFlMNELGYTSEDLQILFYCSSWYVSGQIKEEimkkieq 495 *******************95...69************************77899**********************999******* PP TRM13 183 ............aeeedekeekekeekkeeeeseeekksklsseereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnv 257 +++e+++++k++e+kk+ e+s+ ++k++lsse+++ iG+++kr++d+gR+l+l +kg++ ++vkY++ +s+En+ tr|Q236Z5|Q236Z5_TETTS 496 seqkqvseqlnqIQNENSQDNKQEESKKVIEQSQPNNKEWLSSEKKSLIGKMVKRTVDIGRILNLVKKGKKGRIVKYCDFILSPENF 582 ***********9999999********************************************************************* PP TRM13 258 lLlak 262 +++ak tr|Q236Z5|Q236Z5_TETTS 583 VIIAK 587 **985 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (262 nodes) Target sequences: 26971 (16912921 residues searched) Passed MSV filter: 6886 (0.255311); expected 539.4 (0.02) Passed bias filter: 475 (0.0176115); expected 539.4 (0.02) Passed Vit filter: 35 (0.00129769); expected 27.0 (0.001) Passed Fwd filter: 3 (0.000111231); expected 0.3 (1e-05) Initial search space (Z): 26971 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.53u 0.02s 00:00:00.55 Elapsed: 00:00:00.16 # Mc/sec: 27694.91 // [ok]