# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TRM13.hmm.txt
# target sequence database:        proteomes/Trypanosoma_brucei.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TRM13  [M=262]
Accession:   PF05206.13
Description: Methyltransferase TRM13
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    2.1e-37  128.0   5.7    1.4e-27   95.8   3.2    3.3  2  tr|Q57Y07|Q57Y07_TRYB2  Uncharacterized protein OS=Trypanosom
    5.1e-16   57.9   0.2    8.1e-16   57.3   0.2    1.3  1  tr|Q385P4|Q385P4_TRYB2  Uncharacterized protein OS=Trypanosom


Domain annotation for each sequence (and alignments):
>> tr|Q57Y07|Q57Y07_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.8   3.2   3.2e-31   1.4e-27      21     179 ..     245     468 ..     232     474 .. 0.89
   2 !   30.3   0.1   3.2e-11   1.4e-07     214     261 ..     471     519 ..     469     520 .. 0.92

  Alignments for each domain:
  == domain 1  score: 95.8 bits;  conditional E-value: 3.2e-31
                   TRM13  21 ayvEfGaGkgelsryvnqaleed............................kkenskyvLidrasnrlkaDrklrkdeselaikRlk 79 
                              ++E+GaGk+ l+  +++al +                             +   ++ v +d +  r kaD ++r+    l + Rl+
  tr|Q57Y07|Q57Y07_TRYB2 245 GFLELGAGKAGLAVSLQDALLSGsirychshpgfqerkegrtavnealsadNGGFPRIVVVDMDNFRRKADACVRNSR--LPLVRLR 329
                             689***************99888999**********************9988999*********************99..699**** PP

                   TRM13  80 idIkdLnlsaleelekkkkv............................vavsKHLCGaATDLtLrcllnsekask.kakleglliAl 137
                             i+IkdL+l + +     + +                            vav+KHLCGa TD++L c+++ + +++  a+++++++A+
  tr|Q57Y07|Q57Y07_TRYB2 330 INIKDLDLAKALCGA--STCkrsreetsstsdqctnaikqsvsveeqwVAVGKHLCGACTDFALSCVTAPNLNTEgFASVCAVVFAT 414
                             ********9987633..2223345577999**************************************998887756899******* PP

                   TRM13 138 CChhvCswkeyvn............key.leelgitkeefqiltkmvSWavsgkr 179
                             CCh++C+ k+                 +  +++ ++++ef+++t+m+SWavsg+ 
  tr|Q57Y07|Q57Y07_TRYB2 415 CCHQRCELKHINAllspsecrrgriA-IpGTNHTFSEREFAAITSMSSWAVSGEA 468
                             *********9888999****988642.2357899******************987 PP

  == domain 2  score: 30.3 bits;  conditional E-value: 3.2e-11
                   TRM13 214 eereeiGlkakrlidegRllalkekgfe.aelvkYvekevslEnvlLla 261
                             +er+  G+ +kr+id+ Rl++lk+ gf  + l +Y e++v+ En++++a
  tr|Q57Y07|Q57Y07_TRYB2 471 AERRLTGMCCKRVIDAFRLEYLKQSGFRrTYLCQYAESSVTGENICIVA 519
                             589999*******************9963789**************987 PP

>> tr|Q385P4|Q385P4_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.3   0.2   1.9e-19   8.1e-16      73     261 ..     297     484 ..     225     485 .. 0.80

  Alignments for each domain:
  == domain 1  score: 57.3 bits;  conditional E-value: 1.9e-19
                   TRM13  73 laikRlkidIkdLnlsaleelekkkkvvavsKHLCGaATDLtLrcllnsekaskkakleglliAlCChhvCswkeyvnkeyleel.g 158
                               ++R+   ++d +  + +   + +++ +v+KHLCG+  D  Lr l++s+k       + l++  CC    ++ ey n  +l++  +
  tr|Q385P4|Q385P4_TRYB2 297 YPLHRISKRLQDVDWGNTHI--DFDSCAVVAKHLCGTSVDSCLRHLMASNKL-----PRVLVVVPCCFNKGRYAEYCNPGFLSHVaD 376
                             55666666666666666666..6788999*******************9997.....589*********************887658 PP

                   TRM13 159 itke.efqiltkmvSWavsgkrkse........aeeedekeekekeekkeeeeseeekksklsseereeiGlkakrlidegRllalk 236
                             ++ e +++  t+++ W  s  ++           ++++ + +++  ekk++++ + e++  l  +    i   +  +i++gR+l+l+
  tr|Q385P4|Q385P4_TRYB2 377 VEGElSWEQCTRLTDWNKSCYQQAGnplscsscCSCCNGSYDRRAGEKKVSRKRKMEHF--LPCM--DDIATLVEVIINYGRVLWLR 459
                             99999***********9776664446999998866677777777778877777777776..7666..589***************** PP

                   TRM13 237 ekgfeaelvkYvekevslEnvlLla 261
                             e+g+++++v+Yv++ v++ n +++a
  tr|Q385P4|Q385P4_TRYB2 460 EMGYQTSVVEYVPRCVTPKNRAIVA 484
                             *********************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (262 nodes)
Target sequences:                         8561  (4332363 residues searched)
Passed MSV filter:                       498  (0.0581708); expected 171.2 (0.02)
Passed bias filter:                      265  (0.0309543); expected 171.2 (0.02)
Passed Vit filter:                        17  (0.00198575); expected 8.6 (0.001)
Passed Fwd filter:                         2  (0.000233618); expected 0.1 (1e-05)
Initial search space (Z):               8561  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.10u 0.00s 00:00:00.10 Elapsed: 00:00:00.04
# Mc/sec: 28376.98
//
[ok]