# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TRM13.hmm.txt # target sequence database: proteomes/Xenopus_tropicalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TRM13 [M=262] Accession: PF05206.13 Description: Methyltransferase TRM13 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-84 283.9 0.1 2.2e-84 283.5 0.1 1.2 1 tr|F7EU89|F7EU89_XENTR tRNA methyltransferase 13 homolog (S. 5.3e-06 26.6 3.3 0.019 14.9 0.1 2.8 2 tr|F6PV16|F6PV16_XENTR Glutathione S-transferase, C-terminal ------ inclusion threshold ------ 0.035 14.0 0.0 5.3 6.9 0.0 2.4 2 tr|F6XA95|F6XA95_XENTR Methyltransferase-like 25 OS=Xenopus Domain annotation for each sequence (and alignments): >> tr|F7EU89|F7EU89_XENTR tRNA methyltransferase 13 homolog (S. cerevisiae) OS=Xenopus tropicalis OX=8364 GN=trmt13 PE= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 283.5 0.1 2.8e-88 2.2e-84 1 261 [. 176 461 .. 176 462 .. 0.94 Alignments for each domain: == domain 1 score: 283.5 bits; conditional E-value: 2.8e-88 TRM13 1 lqqsslignleelkllekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnl 87 +qq+s++g+l++l+ll+ s ++vEfGaG+g+ls++v+ a++ + en +++L++ra++r+k+D k r+ ++Rl+idI++L+l tr|F7EU89|F7EU89_XENTR 176 KQQASILGHLDNLGLLSGSCCFVEFGAGRGKLSHWVDIATQGS--ENINFLLVERATTRFKVDGKQRSSV----FERLQIDIQHLCL 256 69*************************************9766..9******************988766....9************ PP TRM13 88 saleele.kkkkvvavsKHLCGaATDLtLrcllnsekask.............................kakleglliAlCChhvCs 144 ++++l+ k+ +v++++KHLCGa TDL+Lrcl++s++ + ++ + g++iAlCChh+C+ tr|F7EU89|F7EU89_XENTR 257 GRVPSLNeKQLPVIGIGKHLCGAGTDLALRCLMQSNSLANgepfpkkprtdtfeqgtvknecdkanpaySTCVGGIAIALCCHHRCD 343 *******999***************************9999***************************999**************** PP TRM13 145 wkeyvnkeyleelgitkeefqiltkmvSWavsgkrkse.aeeedekeekekeekkeeeeseeekksklsseereeiGlkakrlideg 230 w++yv++e++++lg+ ++ef+++++m+SWa++g+r a ++de+ e+e++++++++ ++e+ + l+++ere +G+ +k lid+g tr|F7EU89|F7EU89_XENTR 344 WHHYVGREFFQSLGLDQREFSLFQRMSSWATCGMRLPAkAIQSDEQMESEEHDAEQQNCHSETVERFLTVKERESLGRLCKLLIDYG 430 ***********************************65544455556666666667777778888889******************** PP TRM13 231 RllalkekgfeaelvkYvekevslEnvlLla 261 R+ +l+++g+ a+l++Y+e+evslEnvlL+a tr|F7EU89|F7EU89_XENTR 431 RVDFLQRMGYIAALQYYTEPEVSLENVLLTA 461 *****************************87 PP >> tr|F6PV16|F6PV16_XENTR Glutathione S-transferase, C-terminal domain-containing OS=Xenopus tropicalis OX=8364 GN=gstc # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 2.0 5.9e-05 0.47 96 141 .. 488 525 .. 406 561 .. 0.67 2 ! 14.9 0.1 2.3e-06 0.019 210 260 .. 563 612 .. 538 614 .. 0.87 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 5.9e-05 TRM13 96 kkkvvavsKHLCGaATDLtLrcllnsekaskkakleglliAlCChh 141 ++ +++v+ H CG+ATD+ ++ +++ ++a +++ CC tr|F6PV16|F6PV16_XENTR 488 GSFTIGVALHACGVATDMVMEHCIKARAA--------FVVSPCCYG 525 355699**************999987764........677777765 PP == domain 2 score: 14.9 bits; conditional E-value: 2.3e-06 TRM13 210 klsseereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLl 260 +l+ +er++iG+++ l+d R++a ++ ++++++++ +++ s+ n +++ tr|F6PV16|F6PV16_XENTR 563 QLT-AERRQIGKQCMGLVDLDRAWAAEQSEYKVQVITMEPESCSPKNNMIV 612 444.57889*************************************99886 PP >> tr|F6XA95|F6XA95_XENTR Methyltransferase-like 25 OS=Xenopus tropicalis OX=8364 GN=mettl25 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.00066 5.3 23 44 .. 2 27 .. 1 117 [. 0.82 2 ? 5.0 0.0 0.0025 20 51 143 .. 155 241 .. 135 270 .. 0.69 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.00066 TRM13 23 vEfGaGkgelsryvnqaleed....k 44 +++GaGkg+ls y+ + ++ + + tr|F6XA95|F6XA95_XENTR 2 IDLGAGKGYLSSYLSMKYNLKvygiD 27 789***********999876655552 PP == domain 2 score: 5.0 bits; conditional E-value: 0.0025 TRM13 51 vLidrasnrlkaDrklrkdese.laikRlkidIk.dLnlsaleelekkkkvvavsKHLCGaATDLtLrcllnsekaskkakleglli 135 L ++++++ k+ + k++ ++ l I + +ls++ e + ++ ++v+ H CG tLr +++ + +++++ tr|F6XA95|F6XA95_XENTR 155 SLSEQEKEQRKMENISIKEQRGsRVYLPLTCKITvETELSEIIE--DLEESIMVGLHTCGDLAPNTLRIFTAKPE------IKAVCS 233 55666666666666544444333333333333322456777777..78999*********877778887777666......578888 PP TRM13 136 AlCChhvC 143 CC h+ tr|F6XA95|F6XA95_XENTR 234 VGCCYHLL 241 88999975 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (262 nodes) Target sequences: 24182 (11782085 residues searched) Passed MSV filter: 1533 (0.0633943); expected 483.6 (0.02) Passed bias filter: 594 (0.0245637); expected 483.6 (0.02) Passed Vit filter: 54 (0.00223307); expected 24.2 (0.001) Passed Fwd filter: 3 (0.000124059); expected 0.2 (1e-05) Initial search space (Z): 24182 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.01s 00:00:00.28 Elapsed: 00:00:00.09 # Mc/sec: 34298.96 // [ok]