# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TYW3.hmm.txt
# target sequence database:        proteomes/Amphimedon_queenslandica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TYW3  [M=214]
Accession:   PF02676.13
Description: Methyltransferase TYW3
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence                       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------                       -----------
    6.6e-56  190.3   0.2    1.2e-55  189.5   0.2    1.4  1  tr|A0A1X7TUC4|A0A1X7TUC4_AMPQE  Uncharacterized protein OS=Amphi
    3.1e-46  158.7   0.2    4.1e-46  158.3   0.2    1.2  1  tr|A0A1X7SNK0|A0A1X7SNK0_AMPQE  Uncharacterized protein OS=Amphi
    1.4e-45  156.5   0.2    2.3e-45  155.8   0.2    1.3  1  tr|A0A1X7SHB6|A0A1X7SHB6_AMPQE  Uncharacterized protein OS=Amphi
     0.0033   18.0   0.7     0.0037   17.9   0.1    1.4  2  tr|A0A1X7SV75|A0A1X7SV75_AMPQE  Uncharacterized protein OS=Amphi
  ------ inclusion threshold ------
      0.092   13.3   0.2       0.13   12.9   0.2    1.1  1  tr|A0A1X7THP1|A0A1X7THP1_AMPQE  Uncharacterized protein OS=Amphi


Domain annotation for each sequence (and alignments):
>> tr|A0A1X7TUC4|A0A1X7TUC4_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  189.5   0.2   1.3e-59   1.2e-55       3     213 ..     185     369 ..     183     370 .. 0.91

  Alignments for each domain:
  == domain 1  score: 189.5 bits;  conditional E-value: 1.3e-59
                                     HHHHHHHH....HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE............EESSTT-STT-EEEEE CS
                            TYW3   3 KakiLeeLsvpdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrksaeaeekaaksggkkgggkwlfv 81 
                                     K+++Le+     +d+s+kGs+D++++el++ in++ed++TtSSCsGR+ vf           ++++++gk +g+ wl+ 
  tr|A0A1X7TUC4|A0A1X7TUC4_AMPQE 185 KKRVLEDK----EDASRKGSIDAPVIELVKYINKQEDYYTTSSCSGRIIVF-----------SENTQTGK-EGTLWLLT 247
                                     67777774....9**************************************...........34455555.5568**** PP

                                     ESS---HHHHHHHHCS--..............SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT-TT-EEEEECTTE CS
                            TYW3  82 sHdpvkeeellaelegleeeeesaksseseeeerlivfkfePmILhvlcrslehAqkllsaAlsaGfreSGivslkkkk 160
                                     sH++v+ +++l+ l++ +              + + ++kfeP++Lhv cr+lehAq++l++A+s+Gf++SGi   kk+k
  tr|A0A1X7TUC4|A0A1X7TUC4_AMPQE 248 SHETVSIDNVLSILKDRDIPI-----------SCYTYYKFEPFVLHVSCRTLEHAQAILRIAVSSGFKNSGISVSKKNK 315
                                     *************99997433...........799******************************************** PP

                                     EEEEEE---EEEEEEE.SSTS---HHHHHHHHHHHHHHHHHHHHHHHHHHHHC- CS
                            TYW3 161 vivairsglklevpig.rkkllvseeylkllvklanerfeenkkrierfeealk 213
                                     +i+ +rs+  l++p++ ++kl+v+e+yl  lvk++ne++e+n +rierf++ ++
  tr|A0A1X7TUC4|A0A1X7TUC4_AMPQE 316 MILSVRSTQTLQSPVAfDGKLIVTEQYLCHLVKISNEKLEDNFQRIERFYKLVR 369
                                     ****************8667******************************8765 PP

>> tr|A0A1X7SNK0|A0A1X7SNK0_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  158.3   0.2   4.8e-50   4.1e-46       3     184 ..      13     168 ..      11     169 .] 0.90

  Alignments for each domain:
  == domain 1  score: 158.3 bits;  conditional E-value: 4.8e-50
                                     HHHHHHHH....HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE............EESSTT-STT-EEEEE CS
                            TYW3   3 KakiLeeLsvpdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrksaeaeekaaksggkkgggkwlfv 81 
                                     K+++Le+     +d+s+kGs+D++i+el++ in++ed++TtSSCsGR+ vf           ++++++gk +g+ wl+ 
  tr|A0A1X7SNK0|A0A1X7SNK0_AMPQE  13 KRRVLEDK----EDASRKGSIDAPIIELVKYINKQEDYYTTSSCSGRIIVF-----------SENTRTGK-EGTLWLLT 75 
                                     66777764....9**************************************...........35566666.5568**** PP

                                     ESS---HHHHHHHHCS--..............SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT-TT-EEEEECTTE CS
                            TYW3  82 sHdpvkeeellaelegleeeeesaksseseeeerlivfkfePmILhvlcrslehAqkllsaAlsaGfreSGivslkkkk 160
                                     sH++v+ +++l+ l++++              + + ++kfeP++Lhv cr+lehAq++l++A+s+Gf++SGi   kk+k
  tr|A0A1X7SNK0|A0A1X7SNK0_AMPQE  76 SHETVSIDNVLSVLKDKDIPI-----------SCYTYYKFEPFVLHVSCRTLEHAQAILRIAISSGFKNSGISVSKKNK 143
                                     ***************997433...........799******************************************** PP

                                     EEEEEE---EEEEEEE.SSTS---H CS
                            TYW3 161 vivairsglklevpig.rkkllvse 184
                                     +i+ +rs+  l++p++ ++kl+v e
  tr|A0A1X7SNK0|A0A1X7SNK0_AMPQE 144 IILSVRSTQTLQSPVAfDGKLIVAE 168
                                     ****************865688876 PP

>> tr|A0A1X7SHB6|A0A1X7SHB6_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.8   0.2   2.6e-49   2.3e-45       3     184 ..      48     203 ..      46     204 .] 0.89

  Alignments for each domain:
  == domain 1  score: 155.8 bits;  conditional E-value: 2.6e-49
                                     HHHHHHHH....HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE............EESSTT-STT-EEEEE CS
                            TYW3   3 KakiLeeLsvpdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrksaeaeekaaksggkkgggkwlfv 81 
                                     K+++Le+     +d+s+kGs+D++i+el++ ins+ed++TtSSCsGR+ vf            +++ +  k+g+ wl+ 
  tr|A0A1X7SHB6|A0A1X7SHB6_AMPQE  48 KKRVLEDK----EDASRKGSIDAPIIELVKYINSQEDYYTTSSCSGRIIVF------------SENIQTGKEGTLWLLT 110
                                     77777774....9**************************************............334444446668**** PP

                                     ESS---HHHHHHHHCS--..............SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT-TT-EEEEECTTE CS
                            TYW3  82 sHdpvkeeellaelegleeeeesaksseseeeerlivfkfePmILhvlcrslehAqkllsaAlsaGfreSGivslkkkk 160
                                     sH++v+ +++l+ l++ +              + + ++kfeP++Lhv cr+lehAq++l++A+s+Gf++SGi   kk+k
  tr|A0A1X7SHB6|A0A1X7SHB6_AMPQE 111 SHETVSIDNVLSVLKDRDIPI-----------SCYTYYKFEPFVLHVSCRTLEHAQAILRIAVSSGFKNSGISVSKKNK 178
                                     **************9997433...........799******************************************** PP

                                     EEEEEE---EEEEEEE.SSTS---H CS
                            TYW3 161 vivairsglklevpig.rkkllvse 184
                                     +i+ +rs+  l++p++ ++kl+v e
  tr|A0A1X7SHB6|A0A1X7SHB6_AMPQE 179 IILSVRSTQTLQSPVAfDGKLIVAE 203
                                     ****************865688876 PP

>> tr|A0A1X7SV75|A0A1X7SV75_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.1   4.3e-07    0.0037     186     213 ..       1      28 [.       1      29 [. 0.92
   2 ?   -2.8   0.0      0.93   8.1e+03      18      20 ..      56      58 ..      43      72 .. 0.50

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 4.3e-07
                                     HHHHHHHHHHHHHHHHHHHHHHHHHHC- CS
                            TYW3 186 ylkllvklanerfeenkkrierfeealk 213
                                     yl  lvk++ne++e+n +rierf++ ++
  tr|A0A1X7SV75|A0A1X7SV75_AMPQE   1 YLCHLVKISNEKLEDNFQRIERFYKLVR 28 
                                     8999********************9775 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.93
                                    HHC CS
                            TYW3 18 spk 20
                                    ++k
  tr|A0A1X7SV75|A0A1X7SV75_AMPQE 56 KKK 58
                                    111 PP

>> tr|A0A1X7THP1|A0A1X7THP1_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.2   1.5e-05      0.13      59      98 ..       8      47 ..       3      51 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.5e-05
                                    .......EESSTT-STT-EEEEEESS---HHHHHHHHCS- CS
                            TYW3 59 saeaeekaaksggkkgggkwlfvsHdpvkeeellaelegl 98
                                     +++++k++k+++k+++g+++ vsH+  +++++la+l++ 
  tr|A0A1X7THP1|A0A1X7THP1_AMPQE  8 GKTEKAKEEKTKEKEESGSIVNVSHHITNRKSTLAKLFNF 47
                                    566788999999999********************99986 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (214 nodes)
Target sequences:                        43435  (14716620 residues searched)
Passed MSV filter:                      1567  (0.0360769); expected 868.7 (0.02)
Passed bias filter:                      889  (0.0204674); expected 868.7 (0.02)
Passed Vit filter:                        80  (0.00184183); expected 43.4 (0.001)
Passed Fwd filter:                         5  (0.000115115); expected 0.4 (1e-05)
Initial search space (Z):              43435  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.24u 0.01s 00:00:00.25 Elapsed: 00:00:00.10
# Mc/sec: 31493.57
//
[ok]