# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TYW3.hmm.txt
# target sequence database:        proteomes/Anolis_carolinensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TYW3  [M=214]
Accession:   PF02676.13
Description: Methyltransferase TYW3
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    4.6e-59  199.4   0.0    7.6e-59  198.7   0.0    1.3  1  tr|H9GHH2|H9GHH2_ANOCA  tRNA-yW synthesizing protein 3 homolo
     0.0008   18.9  36.6        2.4    7.5   0.2    9.3 10  tr|H9GH12|H9GH12_ANOCA  Uncharacterized protein OS=Anolis car
  ------ inclusion threshold ------
        4.2    6.7   9.5       0.37   10.1   4.6    1.7  2  tr|G1KTW8|G1KTW8_ANOCA  General transcription factor IIA subu


Domain annotation for each sequence (and alignments):
>> tr|H9GHH2|H9GHH2_ANOCA  tRNA-yW synthesizing protein 3 homolog OS=Anolis carolinensis OX=28377 GN=TYW3 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  198.7   0.0   1.2e-62   7.6e-59      13     213 ..      13     201 ..       6     202 .. 0.91

  Alignments for each domain:
  == domain 1  score: 198.7 bits;  conditional E-value: 1.2e-62
                             ..HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE...............EESSTT-STT-EEEEEESS---HHHHHHHHC CS
                    TYW3  13 pdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrk...saeaeekaaksggkkgggkwlfvsHdpvkeeellaele 96 
                             ++ d s+kGsvDe+i  l++++n +e+++TtSSCsGRv+v+ +         + ++++  + +k++++wl+v+H+ ++ e++l++l+
  tr|H9GHH2|H9GHH2_ANOCA  13 SRADGSRKGSVDEPIEGLVRLLNGREGFCTTSSCSGRVVVLEQP-PqprPPPRGQATTGFEVQKQNCTWLMVTHQICTIEDVLTALQ 98 
                             33799************************************333.2465344677778888899*********************** PP

                             S--..............SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT-TT-EEEEECTTEEEEEEE---EEEEEEESST.S-- CS
                    TYW3  97 gleeeeesaksseseeeerlivfkfePmILhvlcrslehAqkllsaAlsaGfreSGivslkkkkvivairsglklevpigrkk.llv 182
                             + +               +  vfkfeP++Lhv+cr+l++Aq l+++A++aGfr+SGi+  +k+k+i+a+rs+++levp+++k  l+v
  tr|H9GHH2|H9GHH2_ANOCA  99 KAK---------------EDAVFKFEPFVLHVQCRELQDAQLLHTVAIEAGFRNSGITVGRKGKIIMAVRSTHCLEVPLSQKGkLMV 170
                             *95...............5789**********************************************************6555*** PP

                             -HHHHHHHHHHHHHHHHHHHHHHHHHHHHC- CS
                    TYW3 183 seeylkllvklanerfeenkkrierfeealk 213
                             seey++++v++an+++een++ri+rf+++l+
  tr|H9GHH2|H9GHH2_ANOCA 171 SEEYVDFVVRVANQKMEENRRRIDRFYSSLQ 201
                             ***************************9996 PP

>> tr|H9GH12|H9GH12_ANOCA  Uncharacterized protein OS=Anolis carolinensis OX=28377 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.2      0.13     8e+02      46      59 ..      38      73 ..      36     123 .. 0.68
   2 !    6.7   0.4   0.00067       4.1      42      59 ..     137     162 ..     130     234 .. 0.66
   3 ?    2.7   0.2     0.012        72      46      59 ..     248     266 ..     247     315 .. 0.73
   4 ?   -2.0   0.1       0.3   1.9e+03      46      54 ..     383     391 ..     381     424 .. 0.78
   5 !    5.2   0.1    0.0019        12      43      54 ..     486     497 ..     464     544 .. 0.80
   6 !    3.3   0.1    0.0072        45      44      54 ..     592     602 ..     586     634 .. 0.83
   7 ?    1.0   0.0     0.036   2.2e+02      45      55 ..     696     706 ..     688     751 .. 0.78
   8 !    7.5   0.2   0.00038       2.4      40      59 ..     931     958 ..     921    1026 .. 0.65
   9 !    5.3   0.1    0.0018        11      43      58 ..    1039    1054 ..    1027    1117 .. 0.84
  10 !    6.8   0.2   0.00062       3.9      42      56 ..    1155    1169 ..    1144    1242 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.13
                            ES-EEEEE............................ CS
                    TYW3 46 CsGRvsvflegrk......................s 59
                            CsGRv ++l+g                         
  tr|H9GH12|H9GH12_ANOCA 38 CSGRVEMLLNGLWgtvcddgwdlsdaqvvcrelgcG 73
                            ********9887666666666665555555555443 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.00067
                             EEEEES-EEEEE................ CS
                    TYW3  42 TtSSCsGRvsvflegrk..........s 59 
                              tS CsGRv vf +             +
  tr|H9GH12|H9GH12_ANOCA 137 GTSPCSGRVEVFHN--DawgticdagwD 162
                             69**********32..124555555551 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.012
                             ES-EEEEE........... CS
                    TYW3  46 CsGRvsvflegrk.....s 59 
                             CsGRv vf+ g+      +
  tr|H9GH12|H9GH12_ANOCA 248 CSGRVEVFISGEWtsvcdD 266
                             ********99876555540 PP

  == domain 4  score: -2.0 bits;  conditional E-value: 0.3
                             ES-EEEEE. CS
                    TYW3  46 CsGRvsvfl 54 
                             C GRv vf 
  tr|H9GH12|H9GH12_ANOCA 383 CTGRVEVFH 391
                             ********3 PP

  == domain 5  score: 5.2 bits;  conditional E-value: 0.0019
                             EEEES-EEEEE. CS
                    TYW3  43 tSSCsGRvsvfl 54 
                             +S CsGRv vf 
  tr|H9GH12|H9GH12_ANOCA 486 SSNCSGRVEVFH 497
                             688********3 PP

  == domain 6  score: 3.3 bits;  conditional E-value: 0.0072
                             EEES-EEEEE. CS
                    TYW3  44 SSCsGRvsvfl 54 
                             S CsGR+ vf 
  tr|H9GH12|H9GH12_ANOCA 592 SRCSGRIEVFQ 602
                             88********3 PP

  == domain 7  score: 1.0 bits;  conditional E-value: 0.036
                             EES-EEEEE.. CS
                    TYW3  45 SCsGRvsvfle 55 
                              CsGRv +f +
  tr|H9GH12|H9GH12_ANOCA 696 RCSGRVELFHN 706
                             6********32 PP

  == domain 8  score: 7.5 bits;  conditional E-value: 0.00038
                             EEEEEEES-EEEEE.............. CS
                    TYW3  40 lvTtSSCsGRvsvflegrk........s 59 
                             l  tS CsGRv vf + +         +
  tr|H9GH12|H9GH12_ANOCA 931 LNGTSPCSGRVEVFHNDTWgticdagwD 958
                             5679**********43322555555551 PP

  == domain 9  score: 5.3 bits;  conditional E-value: 0.0018
                              EEEES-EEEEE..... CS
                    TYW3   43 tSSCsGRvsvflegrk 58  
                              t  CsGRv vfl+g+ 
  tr|H9GH12|H9GH12_ANOCA 1039 TNGCSGRVEVFLNGEW 1054
                              667*********9986 PP

  == domain 10  score: 6.8 bits;  conditional E-value: 0.00062
                              EEEEES-EEEEE... CS
                    TYW3   42 TtSSCsGRvsvfleg 56  
                               tS CsGRv vf + 
  tr|H9GH12|H9GH12_ANOCA 1155 GTSPCSGRVEVFHND 1169
                              69**********432 PP

>> tr|G1KTW8|G1KTW8_ANOCA  General transcription factor IIA subunit 1 OS=Anolis carolinensis OX=28377 GN=GTF2A1 PE=4 SV=
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   4.6     6e-05      0.37      69     184 ..      68     193 ..      26     200 .. 0.66
   2 ?   -2.1   0.2      0.33     2e+03      61      97 ..     296     332 ..     257     359 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 6e-05
                             STT-STT-EEEEEESS---HHHHHHHHCS--.......................SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHC CS
                    TYW3  69 sggkkgggkwlfvsHdpvkeeellaelegleeeeesaksseseee.........erlivfkfePmILhvlcrslehAqkllsaAlsa 146
                             +++++++ + + ++H+    ++++++ ++  ++++++ +++++++          ++ v   ++  +h  ++ +++A++  ++Al a
  tr|G1KTW8|G1KTW8_ANOCA  68 AQQQQQQQQQHHQQHQHHPPQQHVHHHHHPPQQQQQTVQQSQAQQvlipatqqaPQQQVIVPDSKLMHMNTSGMSAAATAATLALPA 154
                             22222333444555555544555555544444444444444444355666666655555667999********************** PP

                             T-TT-EEEEECTTEEEEEEE---EEEEEEE.SSTS---H CS
                    TYW3 147 GfreSGivslkkkkvivairsglklevpig.rkkllvse 184
                             G      + +++++++  +r+  + + +i  +++++ ++
  tr|G1KTW8|G1KTW8_ANOCA 155 GVTPVQQILTNSGQILQVVRAANGAQYIIQpQQQVVLQQ 193
                             *99888888888788888889888888888543455554 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.33
                             .....EESSTT-STT-EEEEEESS---HHHHHHHHCS CS
                    TYW3  61 eaeekaaksggkkgggkwlfvsHdpvkeeellaeleg 97 
                             e  +++++++++k gg+   v+ +p+++e+ ++  eg
  tr|G1KTW8|G1KTW8_ANOCA 296 EDYDDDEEEDKEKDGGEDGQVEEEPLNSEDDVSDEEG 332
                             3334444555555566666666666666666555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (214 nodes)
Target sequences:                        18528  (9796552 residues searched)
Passed MSV filter:                       755  (0.0407491); expected 370.6 (0.02)
Passed bias filter:                      394  (0.0212651); expected 370.6 (0.02)
Passed Vit filter:                        26  (0.00140328); expected 18.5 (0.001)
Passed Fwd filter:                         6  (0.000323834); expected 0.2 (1e-05)
Initial search space (Z):              18528  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.19u 0.01s 00:00:00.20 Elapsed: 00:00:00.07
# Mc/sec: 29949.46
//
[ok]