# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TYW3.hmm.txt # target sequence database: proteomes/Monodelphis_domestica.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TYW3 [M=214] Accession: PF02676.13 Description: Methyltransferase TYW3 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-55 187.8 0.4 3e-55 187.1 0.0 1.5 2 tr|F7FNE6|F7FNE6_MONDO tRNA-yW synthesizing protein 3 homolo ------ inclusion threshold ------ 0.21 11.1 17.6 1.9 8.0 0.2 5.5 6 tr|F7ENX8|F7ENX8_MONDO Uncharacterized protein OS=Monodelphi 6.6 6.2 6.0 22 4.5 0.1 2.7 3 tr|F6YT70|F6YT70_MONDO Uncharacterized protein OS=Monodelphi Domain annotation for each sequence (and alignments): >> tr|F7FNE6|F7FNE6_MONDO tRNA-yW synthesizing protein 3 homolog OS=Monodelphis domestica OX=13616 GN=TYW3 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 187.1 0.0 4.3e-59 3e-55 13 213 .. 36 213 .. 28 214 .. 0.93 2 ? -3.1 0.1 0.69 4.9e+03 80 98 .. 235 253 .. 219 274 .. 0.49 Alignments for each domain: == domain 1 score: 187.1 bits; conditional E-value: 4.3e-59 ..HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE............EESSTT-STT-EEEEEESS---HHHHHHHHCS-- CS TYW3 13 pdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrksaeaeekaaksggkkgggkwlfvsHdpvkeeellaelegle 99 ++ d+s++G vDe+++el++++n +e+++T SSC+GR+ ++ + +++ + +k+++ wl+v+H+ ++++++l++l++ tr|F7FNE6|F7FNE6_MONDO 36 SKADLSRQGAVDEDVAELVELLNGQEGFFTRSSCAGRILLL---------DGNTNGYKIQKQNCPWLLVTHQLCTKDDMLSALKKA- 112 347**************************************.........4456788888899*********************99. PP ..............SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT-TT-EEEEECTTEEEEEEE---EEEEEEESST.S---HH CS TYW3 100 eeeesaksseseeeerlivfkfePmILhvlcrslehAqkllsaAlsaGfreSGivslkkkkvivairsglklevpigrkk.llvsee 185 ++ v+kfeP+ILhv+cr+l +Aq l+s+A+++Gfr+SGi+ k++k ++a+rs+++levp+++k l+v+ee tr|F7FNE6|F7FNE6_MONDO 113 --------------QGDAVLKFEPFILHVQCRQLRDAQVLHSVAIDSGFRNSGITVGKRGKTVLAVRSTHGLEVPLSHKGrLMVTEE 185 ..............47889**********************************************************6666****** PP HHHHHHHHHHHHHHHHHHHHHHHHHHC- CS TYW3 186 ylkllvklanerfeenkkrierfeealk 213 y+++l+k+an+++eenkkrierf++ l+ tr|F7FNE6|F7FNE6_MONDO 186 YIDFLLKIANQKMEENKKRIERFYSCLQ 213 ************************9886 PP == domain 2 score: -3.1 bits; conditional E-value: 0.69 EEESS---HHHHHHHHCS- CS TYW3 80 fvsHdpvkeeellaelegl 98 + +H+ ++ e + +++ tr|F7FNE6|F7FNE6_MONDO 235 VYTHRRKRKTEKTHGQRSS 253 4444444333333333222 PP >> tr|F7ENX8|F7ENX8_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 GN=CD163 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.2 0.00027 1.9 43 56 .. 270 283 .. 268 317 .. 0.76 2 ? -2.4 0.0 0.4 2.9e+03 46 56 .. 485 495 .. 484 510 .. 0.86 3 ? 1.5 0.2 0.027 1.9e+02 30 54 .. 575 599 .. 555 624 .. 0.75 4 ? 1.9 0.1 0.02 1.4e+02 46 58 .. 717 729 .. 700 783 .. 0.84 5 ? 1.4 0.1 0.028 2e+02 43 58 .. 821 836 .. 806 883 .. 0.77 6 ? 6.5 0.2 0.0008 5.7 44 110 .. 925 1013 .. 923 1027 .. 0.74 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00027 EEEES-EEEEE... CS TYW3 43 tSSCsGRvsvfleg 56 tSSCsGRv v ++ tr|F7ENX8|F7ENX8_MONDO 270 TSSCSGRVEVRVQN 283 9********98644 PP == domain 2 score: -2.4 bits; conditional E-value: 0.4 ES-EEEEE... CS TYW3 46 CsGRvsvfleg 56 CsGRv v +g tr|F7ENX8|F7ENX8_MONDO 485 CSGRVEVKHQG 495 *****998655 PP == domain 3 score: 1.5 bits; conditional E-value: 0.027 HHHHHHC-SSEEEEEEES-EEEEE. CS TYW3 30 lideinsledlvTtSSCsGRvsvfl 54 ++++ + + SSC GRv + + tr|F7ENX8|F7ENX8_MONDO 575 ICSRYTDFRLVDGNSSCEGRVEIQV 599 55555555555568*******9974 PP == domain 4 score: 1.9 bits; conditional E-value: 0.02 ES-EEEEE..... CS TYW3 46 CsGRvsvflegrk 58 C+GRv v+ eg tr|F7ENX8|F7ENX8_MONDO 717 CAGRVEVYHEGAW 729 ********99975 PP == domain 5 score: 1.4 bits; conditional E-value: 0.028 EEEES-EEEEE..... CS TYW3 43 tSSCsGRvsvflegrk 58 t C+GR vf +g+ tr|F7ENX8|F7ENX8_MONDO 821 TQACAGRLEVFYNGTW 836 568********99876 PP == domain 6 score: 6.5 bits; conditional E-value: 0.0008 EEES-EEEEE..................................EESSTT-STT-EEEEEESS---HHHHHHHHCS--....... CS TYW3 44 SSCsGRvsvflegrk......................saeaeekaaksggkkgggkwlfvsHdpvkeeellaelegleeeeesak 106 S CsGRv v+ eg+ ++ + + + g++ g wl H + +e++l++ ++ ++++ ++ tr|F7ENX8|F7ENX8_MONDO 925 SRCSGRVEVWHEGSWgtvcddswdladakvvcqqlgcGSALGAPGEAAFGRGIGPIWLNNVHCKGNESSLWNCTADHWKQTDCEH 1009 78**********9998999999988888888887777444555555566666666899999999999999988888877666655 PP .... CS TYW3 107 sses 110 ++++ tr|F7ENX8|F7ENX8_MONDO 1010 KEDA 1013 5554 PP >> tr|F6YT70|F6YT70_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.2 0.0036 25 46 59 .. 10 27 .. 5 93 .. 0.74 2 ? -1.6 0.1 0.23 1.6e+03 46 57 .. 124 135 .. 120 198 .. 0.75 3 ? 4.5 0.1 0.0031 22 46 59 .. 230 247 .. 220 310 .. 0.75 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.0036 ES-EEEEE.......... CS TYW3 46 CsGRvsvflegrk....s 59 CsGRv v+ +g+ + tr|F6YT70|F6YT70_MONDO 10 CSGRVEVYYQGTWgtvcD 27 ********9887655551 PP == domain 2 score: -1.6 bits; conditional E-value: 0.23 ES-EEEEE.... CS TYW3 46 CsGRvsvflegr 57 C GRv ++ +g tr|F6YT70|F6YT70_MONDO 124 CLGRVEIYYQGI 135 999999997775 PP == domain 3 score: 4.5 bits; conditional E-value: 0.0031 ES-EEEEE.......... CS TYW3 46 CsGRvsvflegrk....s 59 CsGRv v+ +g+ + tr|F6YT70|F6YT70_MONDO 230 CSGRVEVYYQGTWgtvcD 247 ********9887655551 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (214 nodes) Target sequences: 21272 (11266248 residues searched) Passed MSV filter: 933 (0.0438605); expected 425.4 (0.02) Passed bias filter: 499 (0.0234581); expected 425.4 (0.02) Passed Vit filter: 38 (0.00178639); expected 21.3 (0.001) Passed Fwd filter: 3 (0.00014103); expected 0.2 (1e-05) Initial search space (Z): 21272 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.19u 0.01s 00:00:00.20 Elapsed: 00:00:00.08 # Mc/sec: 30137.21 // [ok]