# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TYW3.hmm.txt
# target sequence database:        proteomes/Monodelphis_domestica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TYW3  [M=214]
Accession:   PF02676.13
Description: Methyltransferase TYW3
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.8e-55  187.8   0.4      3e-55  187.1   0.0    1.5  2  tr|F7FNE6|F7FNE6_MONDO  tRNA-yW synthesizing protein 3 homolo
  ------ inclusion threshold ------
       0.21   11.1  17.6        1.9    8.0   0.2    5.5  6  tr|F7ENX8|F7ENX8_MONDO  Uncharacterized protein OS=Monodelphi
        6.6    6.2   6.0         22    4.5   0.1    2.7  3  tr|F6YT70|F6YT70_MONDO  Uncharacterized protein OS=Monodelphi


Domain annotation for each sequence (and alignments):
>> tr|F7FNE6|F7FNE6_MONDO  tRNA-yW synthesizing protein 3 homolog OS=Monodelphis domestica OX=13616 GN=TYW3 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  187.1   0.0   4.3e-59     3e-55      13     213 ..      36     213 ..      28     214 .. 0.93
   2 ?   -3.1   0.1      0.69   4.9e+03      80      98 ..     235     253 ..     219     274 .. 0.49

  Alignments for each domain:
  == domain 1  score: 187.1 bits;  conditional E-value: 4.3e-59
                             ..HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE............EESSTT-STT-EEEEEESS---HHHHHHHHCS-- CS
                    TYW3  13 pdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrksaeaeekaaksggkkgggkwlfvsHdpvkeeellaelegle 99 
                             ++ d+s++G vDe+++el++++n +e+++T SSC+GR+ ++         + +++  + +k+++ wl+v+H+ ++++++l++l++  
  tr|F7FNE6|F7FNE6_MONDO  36 SKADLSRQGAVDEDVAELVELLNGQEGFFTRSSCAGRILLL---------DGNTNGYKIQKQNCPWLLVTHQLCTKDDMLSALKKA- 112
                             347**************************************.........4456788888899*********************99. PP

                             ..............SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT-TT-EEEEECTTEEEEEEE---EEEEEEESST.S---HH CS
                    TYW3 100 eeeesaksseseeeerlivfkfePmILhvlcrslehAqkllsaAlsaGfreSGivslkkkkvivairsglklevpigrkk.llvsee 185
                                           ++  v+kfeP+ILhv+cr+l +Aq l+s+A+++Gfr+SGi+  k++k ++a+rs+++levp+++k  l+v+ee
  tr|F7FNE6|F7FNE6_MONDO 113 --------------QGDAVLKFEPFILHVQCRQLRDAQVLHSVAIDSGFRNSGITVGKRGKTVLAVRSTHGLEVPLSHKGrLMVTEE 185
                             ..............47889**********************************************************6666****** PP

                             HHHHHHHHHHHHHHHHHHHHHHHHHHC- CS
                    TYW3 186 ylkllvklanerfeenkkrierfeealk 213
                             y+++l+k+an+++eenkkrierf++ l+
  tr|F7FNE6|F7FNE6_MONDO 186 YIDFLLKIANQKMEENKKRIERFYSCLQ 213
                             ************************9886 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.69
                             EEESS---HHHHHHHHCS- CS
                    TYW3  80 fvsHdpvkeeellaelegl 98 
                             + +H+  ++ e  +  +++
  tr|F7FNE6|F7FNE6_MONDO 235 VYTHRRKRKTEKTHGQRSS 253
                             4444444333333333222 PP

>> tr|F7ENX8|F7ENX8_MONDO  Uncharacterized protein OS=Monodelphis domestica OX=13616 GN=CD163 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.2   0.00027       1.9      43      56 ..     270     283 ..     268     317 .. 0.76
   2 ?   -2.4   0.0       0.4   2.9e+03      46      56 ..     485     495 ..     484     510 .. 0.86
   3 ?    1.5   0.2     0.027   1.9e+02      30      54 ..     575     599 ..     555     624 .. 0.75
   4 ?    1.9   0.1      0.02   1.4e+02      46      58 ..     717     729 ..     700     783 .. 0.84
   5 ?    1.4   0.1     0.028     2e+02      43      58 ..     821     836 ..     806     883 .. 0.77
   6 ?    6.5   0.2    0.0008       5.7      44     110 ..     925    1013 ..     923    1027 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00027
                             EEEES-EEEEE... CS
                    TYW3  43 tSSCsGRvsvfleg 56 
                             tSSCsGRv v ++ 
  tr|F7ENX8|F7ENX8_MONDO 270 TSSCSGRVEVRVQN 283
                             9********98644 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.4
                             ES-EEEEE... CS
                    TYW3  46 CsGRvsvfleg 56 
                             CsGRv v  +g
  tr|F7ENX8|F7ENX8_MONDO 485 CSGRVEVKHQG 495
                             *****998655 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.027
                             HHHHHHC-SSEEEEEEES-EEEEE. CS
                    TYW3  30 lideinsledlvTtSSCsGRvsvfl 54 
                             ++++   +  +   SSC GRv + +
  tr|F7ENX8|F7ENX8_MONDO 575 ICSRYTDFRLVDGNSSCEGRVEIQV 599
                             55555555555568*******9974 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.02
                             ES-EEEEE..... CS
                    TYW3  46 CsGRvsvflegrk 58 
                             C+GRv v+ eg  
  tr|F7ENX8|F7ENX8_MONDO 717 CAGRVEVYHEGAW 729
                             ********99975 PP

  == domain 5  score: 1.4 bits;  conditional E-value: 0.028
                             EEEES-EEEEE..... CS
                    TYW3  43 tSSCsGRvsvflegrk 58 
                             t  C+GR  vf +g+ 
  tr|F7ENX8|F7ENX8_MONDO 821 TQACAGRLEVFYNGTW 836
                             568********99876 PP

  == domain 6  score: 6.5 bits;  conditional E-value: 0.0008
                              EEES-EEEEE..................................EESSTT-STT-EEEEEESS---HHHHHHHHCS--....... CS
                    TYW3   44 SSCsGRvsvflegrk......................saeaeekaaksggkkgggkwlfvsHdpvkeeellaelegleeeeesak 106 
                              S CsGRv v+ eg+                        ++  +  + + g++ g  wl   H + +e++l++   ++ ++++ ++
  tr|F7ENX8|F7ENX8_MONDO  925 SRCSGRVEVWHEGSWgtvcddswdladakvvcqqlgcGSALGAPGEAAFGRGIGPIWLNNVHCKGNESSLWNCTADHWKQTDCEH 1009
                              78**********9998999999988888888887777444555555566666666899999999999999988888877666655 PP

                              .... CS
                    TYW3  107 sses 110 
                              ++++
  tr|F7ENX8|F7ENX8_MONDO 1010 KEDA 1013
                              5554 PP

>> tr|F6YT70|F6YT70_MONDO  Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.2    0.0036        25      46      59 ..      10      27 ..       5      93 .. 0.74
   2 ?   -1.6   0.1      0.23   1.6e+03      46      57 ..     124     135 ..     120     198 .. 0.75
   3 ?    4.5   0.1    0.0031        22      46      59 ..     230     247 ..     220     310 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0036
                            ES-EEEEE.......... CS
                    TYW3 46 CsGRvsvflegrk....s 59
                            CsGRv v+ +g+     +
  tr|F6YT70|F6YT70_MONDO 10 CSGRVEVYYQGTWgtvcD 27
                            ********9887655551 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.23
                             ES-EEEEE.... CS
                    TYW3  46 CsGRvsvflegr 57 
                             C GRv ++ +g 
  tr|F6YT70|F6YT70_MONDO 124 CLGRVEIYYQGI 135
                             999999997775 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.0031
                             ES-EEEEE.......... CS
                    TYW3  46 CsGRvsvflegrk....s 59 
                             CsGRv v+ +g+     +
  tr|F6YT70|F6YT70_MONDO 230 CSGRVEVYYQGTWgtvcD 247
                             ********9887655551 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (214 nodes)
Target sequences:                        21272  (11266248 residues searched)
Passed MSV filter:                       933  (0.0438605); expected 425.4 (0.02)
Passed bias filter:                      499  (0.0234581); expected 425.4 (0.02)
Passed Vit filter:                        38  (0.00178639); expected 21.3 (0.001)
Passed Fwd filter:                         3  (0.00014103); expected 0.2 (1e-05)
Initial search space (Z):              21272  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.19u 0.01s 00:00:00.20 Elapsed: 00:00:00.08
# Mc/sec: 30137.21
//
[ok]