# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TYW3.hmm.txt # target sequence database: proteomes/Strongylocentrotus_purpuratus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TYW3 [M=214] Accession: PF02676.13 Description: Methyltransferase TYW3 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-42 144.3 5.7 5.5e-30 105.0 0.3 2.9 3 tr|W4ZK25|W4ZK25_STRPU Uncharacterized protein OS=Strongyloc ------ inclusion threshold ------ 0.079 13.0 0.1 0.1 12.6 0.1 1.2 1 tr|W4XK92|W4XK92_STRPU Uncharacterized protein OS=Strongyloc Domain annotation for each sequence (and alignments): >> tr|W4ZK25|W4ZK25_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.0 0.3 3.8e-34 5.5e-30 13 139 .. 12 116 .. 3 117 .. 0.89 2 ! 41.4 0.0 1.1e-14 1.6e-10 163 213 .. 116 167 .. 115 168 .. 0.93 3 ? 0.1 0.3 0.046 6.6e+02 62 87 .. 174 211 .. 169 248 .. 0.54 Alignments for each domain: == domain 1 score: 105.0 bits; conditional E-value: 3.8e-34 ..HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE............EESSTT-STT-EEEEEESS---HHHHHHHHCS-- CS TYW3 13 pdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrksaeaeekaaksggkkgggkwlfvsHdpvkeeellaelegle 99 + td s+kG++D+ i++l++ in++++++TtSSCsGR+ +f +e+ ++ + +k+g++wlfvsH+ +++++++++l +e tr|W4ZK25|W4ZK25_STRPU 12 KCTDFSRKGEIDQFIISLVEIINNHDSYFTTSSCSGRIILF---------SESLDEYSVRKKGCRWLFVSHESASTADIISALDLEE 89 339**************************************.........45667777778999*****************999886 PP ..............SSEEEEEEE--EEEEEESSHHHHHHH CS TYW3 100 eeeesaksseseeeerlivfkfePmILhvlcrslehAqkl 139 + ++ vfkfeP++Lhv+c+++ehA+k+ tr|W4ZK25|W4ZK25_STRPU 90 T-------------KGEAVFKFEPFVLHVQCETTEHARKM 116 3.............6789*******************986 PP == domain 2 score: 41.4 bits; conditional E-value: 1.1e-14 EEEE---EEEEEEESST.S---HHHHHHHHHHHHHHHHHHHHHHHHHHHHC- CS TYW3 163 vairsglklevpigrkk.llvseeylkllvklanerfeenkkrierfeealk 213 +airs+++levp+ ++ llvse+y++++v+lan++++en +rie+f++ l+ tr|W4ZK25|W4ZK25_STRPU 116 MAIRSTHGLEVPLTKEGrLLVSEDYIDFIVSLANSKMKENFNRIEKFQDTLQ 167 69************5555*******************************997 PP == domain 3 score: 0.1 bits; conditional E-value: 0.046 ....EESSTT-STT-EEEEEESS--............- CS TYW3 62 aeekaaksggkkgggkwlfvsHdpv............k 87 ++++a++++ k+++g+ l H + k tr|W4ZK25|W4ZK25_STRPU 174 KRNEADPNSRKNKHGRRLNERHPVKhkltqtdtsdteK 211 44555556666666666666665543332443332220 PP >> tr|W4XK92|W4XK92_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 7.3e-06 0.1 38 60 .. 83 105 .. 75 124 .. 0.78 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 7.3e-06 SSEEEEEEES-EEEEE....... CS TYW3 38 edlvTtSSCsGRvsvflegrksa 60 e ++TtSSCsG v+ +l g +++ tr|W4XK92|W4XK92_STRPU 83 EMVMTTSSCSGDVAAVLCGVEKR 105 6689*********9998776643 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (214 nodes) Target sequences: 28594 (14266044 residues searched) Passed MSV filter: 1175 (0.0410925); expected 571.9 (0.02) Passed bias filter: 585 (0.0204588); expected 571.9 (0.02) Passed Vit filter: 41 (0.00143387); expected 28.6 (0.001) Passed Fwd filter: 3 (0.000104917); expected 0.3 (1e-05) Initial search space (Z): 28594 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.25u 0.01s 00:00:00.26 Elapsed: 00:00:00.11 # Mc/sec: 27753.94 // [ok]