# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TYW3.hmm.txt
# target sequence database:        proteomes/Thermococcus_kodakarensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TYW3  [M=214]
Accession:   PF02676.13
Description: Methyltransferase TYW3
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence              Description
    ------- ------ -----    ------- ------ -----   ---- --  --------              -----------
    1.7e-46  155.3   0.0    2.2e-46  155.0   0.0    1.1  1  sp|Q5JFK6|TYW31_THEKO  tRNA(Phe) 7-((3-amino-3-carboxypropyl)
    3.1e-41  138.2   0.0      4e-41  137.8   0.0    1.1  1  sp|Q5JES6|TYW32_THEKO  tRNA(Phe) 7-((3-amino-3-carboxypropyl)


Domain annotation for each sequence (and alignments):
>> sp|Q5JFK6|TYW31_THEKO  tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1 OS=Ther
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.0   0.0   1.9e-49   2.2e-46       2     213 ..      11     193 ..      10     194 .. 0.95

  Alignments for each domain:
  == domain 1  score: 155.0 bits;  conditional E-value: 1.9e-49
                            HHHHHHHHH....HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE............EESSTT-STT-EEEEEESS---HH CS
                   TYW3   2 rKakiLeeLsvpdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrksaeaeekaaksggkkgggkwlfvsHdpvkee 89 
                            +K+k++e L    +++ ++ +vD++i++l+++in+l++++TtSSCsGR+sv+            ++++ g+k ++ wl ++H++v+ e
  sp|Q5JFK6|TYW31_THEKO  11 QKEKAMEGL----RKALEEDKVDHDIIPLLEKINALQNYFTTSSCSGRISVM------------EMPHFGDKVNSVWLGKWHREVRLE 82 
                            799999999....999************************************............78888888999************* PP

                            HHHHHHCS--..............SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT-TT-EEEEECTTEEEEEEE---EEEEEEES CS
                   TYW3  90 ellaelegleeeeesaksseseeeerlivfkfePmILhvlcrslehAqkllsaAlsaGfreSGivslkkkkvivairsglklevpigr 177
                            e+l+++ +++              +++++f + ++ILhv +r+le+A +ll++A+  Gf++S i+s+++kk +v+irs+++++vp+g+
  sp|Q5JFK6|TYW31_THEKO  83 EVLEAVGKHR--------------SGQLWFLVRSPILHVGARTLEDAVRLLNLAIGLGFKYSNIKSVSHKKLVVEIRSTERMDVPLGE 156
                            ******9997..............789************************************************************5 PP

                            ST.S---HHHHHHHHHHHHHHHHHHHHHHHHHHHHC- CS
                   TYW3 178 kk.llvseeylkllvklanerfeenkkrierfeealk 213
                            +  l+v+e+y++ +v+lan ++++ k +++r+ee+++
  sp|Q5JFK6|TYW31_THEKO 157 NGeLWVDEAYIEKIVNLANAQVRRFKGKLKRLEEEIE 193
                            555*******************************997 PP

>> sp|Q5JES6|TYW32_THEKO  tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 2 OS=Ther
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.8   0.0   3.4e-44     4e-41       2     213 ..       3     184 ..       2     185 .. 0.95

  Alignments for each domain:
  == domain 1  score: 137.8 bits;  conditional E-value: 3.4e-44
                            HHHHHHHHH....HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE............EESSTT-STT-EEEEEESS---HH CS
                   TYW3   2 rKakiLeeLsvpdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrksaeaeekaaksggkkgggkwlfvsHdpvkee 89 
                             K+++L++L      + + G+vD +i++l+ +ins ++++TtSSCsGR+ ++            ++++ g k  ++wl++ H+p++ e
  sp|Q5JES6|TYW32_THEKO   3 AKREALQSL----FTAMRDGKVDGDIIDLLLLINSIKGIYTTSSCSGRIGII------------EEPALGAKPLSRWLIKVHRPIEFE 74 
                            588899999....8999***********************************............67888888999************* PP

                            HHHHHHCS--..............SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT-TT-EEEEECTTEEEEEEE---EEEEEEES CS
                   TYW3  90 ellaelegleeeeesaksseseeeerlivfkfePmILhvlcrslehAqkllsaAlsaGfreSGivslkkkkvivairsglklevpigr 177
                            e+ ++l++ +              e+ i +k +P+I+hv +++le+A+kl++++l++Gf+++  + ++k +++v+i +++ l  p+gr
  sp|Q5JES6|TYW32_THEKO  75 EAKEALKNAK--------------EGIIFLKSQPPIFHVVAEDLEKARKLHELGLASGFKYTTFKVISK-RYLVEINATEYLTAPLGR 147
                            *****99997..............79******************************************9.*****************6 PP

                            ST.S---HHHHHHHHHHHHHHHHHHHHHHHHHHHHC- CS
                   TYW3 178 kk.llvseeylkllvklanerfeenkkrierfeealk 213
                            +  +lv++ yl++ v++ ne++++ k r+ r+ee+++
  sp|Q5JES6|TYW32_THEKO 148 DGrVLVDDGYLRFAVEIGNEMLRRSKGRLPRLEENFR 184
                            666******************************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (214 nodes)
Target sequences:                         2301  (637680 residues searched)
Passed MSV filter:                        55  (0.0239027); expected 46.0 (0.02)
Passed bias filter:                       48  (0.0208605); expected 46.0 (0.02)
Passed Vit filter:                         5  (0.00217297); expected 2.3 (0.001)
Passed Fwd filter:                         2  (0.000869187); expected 0.0 (1e-05)
Initial search space (Z):               2301  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01
# Mc/sec: 13646.35
//
[ok]