# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TYW3.hmm.txt
# target sequence database: proteomes/Trypanosoma_brucei.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TYW3 [M=214]
Accession: PF02676.13
Description: Methyltransferase TYW3
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.5e-57 192.6 0.0 3.2e-57 192.3 0.0 1.1 1 tr|Q382R4|Q382R4_TRYB2 Uncharacterized protein OS=Trypanosom
2.1e-49 166.7 0.0 2.4e-49 166.5 0.0 1.0 1 tr|Q381E4|Q381E4_TRYB2 Uncharacterized protein OS=Trypanosom
Domain annotation for each sequence (and alignments):
>> tr|Q382R4|Q382R4_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 192.3 0.0 7.4e-61 3.2e-57 2 210 .. 63 321 .. 62 325 .. 0.89
Alignments for each domain:
== domain 1 score: 192.3 bits; conditional E-value: 7.4e-61
HHHHHHHHH....HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE........................EESSTT-STT- CS
TYW3 2 rKakiLeeLsvpdtdkspkGsvDekirelideinsledlvTtSSCsGRvsvf............legrksaeaeekaaksggkkggg 76
+K++++++Ls++ +d+spkG vD+k++++++++n+++d+vT SSCsGR+++f ++g++s+++++ k+g+k++ g
tr|Q382R4|Q382R4_TRYB2 63 HKQRVMSNLSSNMCDHSPKGGVDRKCLKVMELLNNHQDYVTVSSCSGRIALFhstpiletlhdsVNGSSSTKSAAVVGKRGSKDALG 149
8***************************************************66666555555445555999999999*****9999 PP
EEEEEESS---HHHHHHHHCS--................................................SSEEEEEEE--EEEEE CS
TYW3 77 kwlfvsHdpvkeeellaelegleeeeesaksseseee..................................erlivfkfePmILhvl 129
wl+v+H +++eee+ + ++gl e++++s+++++ +++++k+eP+++hv+
tr|Q382R4|Q382R4_TRYB2 150 -WLVVKHGELTEEEINQIVKGLCGDEAEDSSNTHSSPqvrevaerkfngdedeldgvwmqtgvlapiplpsFGTVTLKMEPFVMHVA 235
.*********9999999999887655554444444447889999******************************************* PP
ESSHHHHHHHHHHHHH.CT-TT-EEEEECTTEEEEEEE..---EEEEEEE..SST.S---HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
TYW3 130 crslehAqkllsaAls.aGfreSGivslkkkkvivair..sglklevpig..rkk.llvseeylkllvklanerfeenkkrierfee 210
cr++e++++ll+aA++ aGfr+SG++ k +v++air +g++l++p++ + +++y+++l+ lane++++n+ r++r+e
tr|Q382R4|Q382R4_TRYB2 236 CRTMESGKRLLTAAATeAGFRNSGVTPPGK-RVVCAIRnaTGVGLDIPLVvdGVNyARGQHSYVRRLLLLANEKMRNNDLRRHRLEV 321
***********988777************9.*******************99556699**************************986 PP
>> tr|Q381E4|Q381E4_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 166.5 0.0 5.7e-53 2.4e-49 1 213 [. 30 293 .. 30 294 .. 0.87
Alignments for each domain:
== domain 1 score: 166.5 bits; conditional E-value: 5.7e-53
HHHHHHHHHH....HHHHHCCHC-GGGHHHHHHHHC.-SSEEEEEEES-EEEEE.............................EESS CS
TYW3 1 erKakiLeeLsvpdtdkspkGsvDekirelideins.ledlvTtSSCsGRvsvflegrk.................saeaeekaaks 69
+r++kiLe+L+ +++dks +G+vD+++++l++ in+ ++ +vT+SSCsGRvs+f g+ +a+a+ +++k+
tr|Q381E4|Q381E4_TRYB2 30 QRRQKILEDLQENKNDKSLAGRVDPQVAPLVQFINEhFSCYVTSSSCSGRVSLFHKGQLsagcpinplaeakvlkaDANADMHNRKR 116
689********************************63799**************8887799999****9999999877888899999 PP
TT-STT-EEEEEESS--......-HHHHHHHHCS--............................SSEEEEEEE--EEEEEESSHHHH CS
TYW3 70 ggkkgggkwlfvsHdpv......keeellaelegleeeeesaksseseee..............erlivfkfePmILhvlcrslehA 136
g+ ++g+ lf+sHdp+ +++l+ l + ee+++++ + e + + ++l+ +kfePmI+hv+c++l++A
tr|Q381E4|Q381E4_TRYB2 117 GAFGQGA--LFQSHDPIpnveemVTQRLVPVLGSFEEWRSRQLQLEGGLKlmqekkyfdsllheTELLELKFEPMIVHVQCETLDDA 201
9998875..*********9999966666666666666666666555555567777788889999*********************** PP
HHHHHHHHHCT-TT-EEEEECTT.....EEEEEEE---EEEEEEE.SST.S---HHH........HHHHHHHHHHHHHHHHHHHHHH CS
TYW3 137 qkllsaAlsaGfreSGivslkkk.....kvivairsglklevpig.rkk.llvseey........lkllvklanerfeenkkrierf 208
++ll++A ++G +eSGi s++++ k++++i+s+l++ p++ ++ ll +++ l+ + ++n f n++r+ rf
tr|Q381E4|Q381E4_TRYB2 202 ARLLQCANESGQMESGILSCSRGaneqrKITCCITSSLRVALPLFaQGCwLLGHPKFdsaewrslLTNALVHMNVLFGVNEQRRGRF 288
*********************999*********************83344555555556666666999999**************** PP
HHHC- CS
TYW3 209 eealk 213
e+l+
tr|Q381E4|Q381E4_TRYB2 289 LEKLQ 293
***98 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (214 nodes)
Target sequences: 8561 (4332363 residues searched)
Passed MSV filter: 319 (0.037262); expected 171.2 (0.02)
Passed bias filter: 192 (0.0224273); expected 171.2 (0.02)
Passed Vit filter: 23 (0.0026866); expected 8.6 (0.001)
Passed Fwd filter: 2 (0.000233618); expected 0.1 (1e-05)
Initial search space (Z): 8561 [actual number of targets]
Domain search space (domZ): 2 [number of targets reported over threshold]
# CPU time: 0.08u 0.00s 00:00:00.08 Elapsed: 00:00:00.03
# Mc/sec: 30904.19
//
[ok]