# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TYW3.hmm.txt
# target sequence database:        proteomes/Xenopus_tropicalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TYW3  [M=214]
Accession:   PF02676.13
Description: Methyltransferase TYW3
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.7e-58  197.9   1.1    2.7e-58  197.2   1.1    1.3  1  tr|F7EK24|F7EK24_XENTR  tRNA-yW synthesizing protein 3 homolo
  ------ inclusion threshold ------
       0.14   11.9   0.0        0.2   11.4   0.0    1.2  1  sp|Q5M905|NPL_XENTR     N-acetylneuraminate lyase OS=Xenopus 
       0.83    9.4   4.7         49    3.6   0.1    3.6  4  tr|F6QXG6|F6QXG6_XENTR  Uncharacterized protein OS=Xenopus tr


Domain annotation for each sequence (and alignments):
>> tr|F7EK24|F7EK24_XENTR  tRNA-yW synthesizing protein 3 homolog OS=Xenopus tropicalis OX=8364 GN=tyw3 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  197.2   1.1   3.4e-62   2.7e-58      11     212 ..      11     192 ..       2     194 .. 0.92

  Alignments for each domain:
  == domain 1  score: 197.2 bits;  conditional E-value: 3.4e-62
                             .......HHHHHCCHC-GGGHHHHHHHHC-SSEEEEEEES-EEEEE............EESSTT-STT-EEEEEESS---HHHHHHH CS
                    TYW3  11 svpd...tdkspkGsvDekirelideinsledlvTtSSCsGRvsvflegrksaeaeekaaksggkkgggkwlfvsHdpvkeeellae 94 
                             ++++    d s+kGsvDe+i e +++in++e+++TtSSCsGRv ++         +e+ ++s  +k++++wlfv+H+ +k ++++a+
  tr|F7EK24|F7EK24_XENTR  11 KQQSlrkADVSKKGSVDEDIEETVRLINQQERYFTTSSCSGRVIMI---------NETLDSSIIQKQNCSWLFVTHQLCKPDDVFAA 88 
                             33333349**************************************.........56777888888999****************** PP

                             HCS--..............SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT-TT-EEEEECTTEEEEEEE---EEEEEEESST.S CS
                    TYW3  95 legleeeeesaksseseeeerlivfkfePmILhvlcrslehAqkllsaAlsaGfreSGivslkkkkvivairsglklevpigrkk.l 180
                             l++                ++ +v+kfeP++Lhv+c++le+Aq l+ +A+++Gfr+SGi+  kk+k+i+a+rs+++levp+ ++  +
  tr|F7EK24|F7EK24_XENTR  89 LKNA---------------TGDVVLKFEPFVLHVQCHKLEDAQILHGVAINSGFRNSGITVGKKGKIIMAVRSTHGLEVPLTQNGkC 160
                             **99...............589************************************************************6556* PP

                             ---HHHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
                    TYW3 181 lvseeylkllvklanerfeenkkrierfeeal 212
                             lvs+ey+++lv++an+++eenk+ri rf++ l
  tr|F7EK24|F7EK24_XENTR 161 LVSQEYIEFLVQTANRKMEENKRRITRFHSCL 192
                             ****************************9987 PP

>> sp|Q5M905|NPL_XENTR  N-acetylneuraminate lyase OS=Xenopus tropicalis OX=8364 GN=npl PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   2.5e-05       0.2     114     148 ..      71     105 ..      29     119 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.5e-05
                          SSEEEEEEE--EEEEEESSHHHHHHHHHHHHHCT- CS
                 TYW3 114 erlivfkfePmILhvlcrslehAqkllsaAlsaGf 148
                           ++ + k++ +I+hv c sl++ ++l + A+s+G 
  sp|Q5M905|NPL_XENTR  71 VKQARGKMDNVIIHVGCLSLSDSKDLAAHAASCGA 105
                          666677999************************95 PP

>> tr|F6QXG6|F6QXG6_XENTR  Uncharacterized protein OS=Xenopus tropicalis OX=8364 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.1      0.18   1.4e+03      46      59 ..      30      53 ..      29      85 .. 0.66
   2 ?    3.6   0.1    0.0061        49      44      69 ..     134     163 ..     130     207 .. 0.59
   3 ?    2.7   0.0     0.011        93      43      59 ..     239     259 ..     228     301 .. 0.79
   4 ?    2.4   0.1     0.014   1.1e+02      46      59 ..     347     368 ..     337     433 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.18
                            ES-EEEEE................ CS
                    TYW3 46 CsGRvsvflegrk..........s 59
                            C GRv ++ +g+           s
  tr|F6QXG6|F6QXG6_XENTR 30 CEGRVEIYYNGTWgtvcddlwnmS 53
                            99******9887655555555540 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.0061
                             EEES-EEEEE.....................EESS CS
                    TYW3  44 SSCsGRvsvflegrk.........saeaeekaaks 69 
                             SSC GR  v  +g+          +     k+ak 
  tr|F6QXG6|F6QXG6_XENTR 134 SSCKGRLEVNHNGTWgtvcndqwdK-----KDAKV 163
                             9*********888776666443321.....33333 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.011
                             EEEES-EEEEE.......... CS
                    TYW3  43 tSSCsGRvsvflegrk....s 59 
                              SSC GR  v  +g+     +
  tr|F6QXG6|F6QXG6_XENTR 239 NSSCKGRLEVNHNGTWgtvcN 259
                             5*********98777644442 PP

  == domain 4  score: 2.4 bits;  conditional E-value: 0.014
                             ES-EEEEE.............. CS
                    TYW3  46 CsGRvsvflegrk........s 59 
                             C+GR  vf +g+         +
  tr|F6QXG6|F6QXG6_XENTR 347 CAGRLEVFYDGEWgsvcdddwD 368
                             ********99986555555550 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (214 nodes)
Target sequences:                        24182  (11782085 residues searched)
Passed MSV filter:                       868  (0.0358945); expected 483.6 (0.02)
Passed bias filter:                      484  (0.0200149); expected 483.6 (0.02)
Passed Vit filter:                        41  (0.00169548); expected 24.2 (0.001)
Passed Fwd filter:                         5  (0.000206765); expected 0.2 (1e-05)
Initial search space (Z):              24182  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.19u 0.01s 00:00:00.20 Elapsed: 00:00:00.08
# Mc/sec: 31517.08
//
[ok]