# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Trm112p.hmm.txt # target sequence database: proteomes/Drosophila_melanogaster.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Trm112p [M=68] Accession: PF03966.15 Description: Trm112p-like protein Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-19 68.5 0.0 5.3e-19 68.2 0.0 1.1 1 sp|Q9VP65|TR112_DROME Multifunctional methyltransferase sub ------ inclusion threshold ------ 0.17 12.1 6.0 0.74 10.1 0.4 4.1 3 tr|A8DYD1|A8DYD1_DROME Combgap, isoform L OS=Drosophila mela 0.21 11.8 6.9 27 5.0 0.2 4.5 4 tr|Q95RQ8|Q95RQ8_DROME LD15650p OS=Drosophila melanogaster O 1.4 9.2 9.9 36 4.7 7.1 3.6 2 sp|P07665|SRYB_DROME Serendipity locus protein beta OS=Dro 2.5 8.4 7.5 20 5.5 2.7 3.4 3 sp|M9MRI4|TRIM9_DROME E3 ubiquitin-protein ligase TRIM9 OS= 5.2 7.4 7.6 8.1 6.7 0.8 3.7 3 tr|B6VQ99|B6VQ99_DROME Neuroectoderm-expressed 2, isoform A Domain annotation for each sequence (and alignments): >> sp|Q9VP65|TR112_DROME Multifunctional methyltransferase subunit TRM112-like protein OS=Drosophila melanogaster OX=72 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.2 0.0 2.3e-22 5.3e-19 1 68 [] 2 113 .. 2 113 .. 0.98 Alignments for each domain: == domain 1 score: 68.2 bits; conditional E-value: 2.3e-22 BTGGCCC-B-TTTHH.....C-..........................-HHHHHHHHH.TT---.S-SS----S...........CHH CS Trm112p 1 kllllniLaCpackg.....pL..........................dwealvevaa.lglne.lpkekpedy...........ell 44 kl ++n+L++ a+kg pL dw+a++ +a+ ++l+e +p+ +pe++ +ll sp|Q9VP65|TR112_DROME 2 KLSTYNFLTSVAIKGvkvgfPLkltinkkevvesefnptfverilpklDWSAVYGAAQvAELTEdIPAVQPENIvenelllqklhHLL 89 6889****************8899**************************************************************** PP TTEECCCCEEEETTTTEEEEEETT CS Trm112p 45 leldieegeLvCpncgraYpIkdG 68 +e+d++eg+L Cp++gr++pI+dG sp|Q9VP65|TR112_DROME 90 FEIDVLEGQLECPETGRVFPISDG 113 ***********************9 PP >> tr|A8DYD1|A8DYD1_DROME Combgap, isoform L OS=Drosophila melanogaster OX=7227 GN=cg PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.4 0.00032 0.74 41 66 .. 353 388 .. 321 389 .. 0.69 2 ? -0.5 0.4 0.65 1.5e+03 54 64 .. 432 442 .. 396 442 .. 0.66 3 ? 1.4 0.0 0.17 3.9e+02 53 63 .. 572 582 .. 526 584 .. 0.85 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00032 S............CHHTTEECCCCEEEETTTTEEEEEE CS Trm112p 41 y............ellleldieegeLvCpncgraYpIk 66 + +++ e +vC +cgra+p k tr|A8DYD1|A8DYD1_DROME 353 CkksftlkhhlltH--SRVHSRERPFVCQECGRAFPLK 388 33445555434331..357888899***********76 PP == domain 2 score: -0.5 bits; conditional E-value: 0.65 EEETTTTEEEE CS Trm112p 54 LvCpncgraYp 64 +vC +cg +p tr|A8DYD1|A8DYD1_DROME 432 FVCAECGASFP 442 47777777776 PP == domain 3 score: 1.4 bits; conditional E-value: 0.17 EEEETTTTEEE CS Trm112p 53 eLvCpncgraY 63 ++vC++cg a+ tr|A8DYD1|A8DYD1_DROME 572 QFVCRECGSAF 582 79******998 PP >> tr|Q95RQ8|Q95RQ8_DROME LD15650p OS=Drosophila melanogaster OX=7227 GN=pita PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 2.6 6e+03 33 58 .. 127 162 .. 112 163 .. 0.64 2 ? 3.4 0.0 0.039 90 49 65 .. 281 297 .. 244 299 .. 0.79 3 ? 3.0 1.0 0.05 1.2e+02 41 63 .. 459 493 .. 371 494 .. 0.80 4 ? 5.0 0.2 0.012 27 8 51 .. 511 560 .. 507 564 .. 0.75 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2.6 S-SS----S..............CHHTTEECCCCEEEETT CS Trm112p 33 lpkekpedy..............ellleldieegeLvCpn 58 p+e+p++ + ++++e ++v p+ tr|Q95RQ8|Q95RQ8_DROME 127 EPSETPKKLlntmaksssqviieD----VQVLESAMVTPR 162 455666655666677777644432....677778888776 PP == domain 2 score: 3.4 bits; conditional E-value: 0.039 CCCCEEEETTTTEEEEE CS Trm112p 49 ieegeLvCpncgraYpI 65 + + ++ Cp+c r +p tr|Q95RQ8|Q95RQ8_DROME 281 VATDVFPCPDCERSFPL 297 5567788********96 PP == domain 3 score: 3.0 bits; conditional E-value: 0.05 S............CHHTTEECCCCEEEETTTTEEE CS Trm112p 41 y............ellleldieegeLvCpncgraY 63 +l ++ + ++vC++c+ Y tr|Q95RQ8|Q95RQ8_DROME 459 ChksymlshhlsrHLRTHTQTSDASFVCSECKVSY 493 144455555577755555888889********999 PP == domain 4 score: 5.0 bits; conditional E-value: 0.012 -B-TTTHHC-.-HHHHHHHHH.TT---.S-SS----S...CHHTTEECCC CS Trm112p 8 LaCpackgpL.dwealvevaa.lglne.lpkekpedy...ellleldiee 51 L+Cp+c+++ d +++ + +++e + e ++++ + +l+ +ie+ tr|Q95RQ8|Q95RQ8_DROME 511 LKCPMCRKQIeDIDSVESHMDqHKQSErHACEFCDHIfltQKCLQRHIED 560 9*******885556666666667777777777777779987788888876 PP >> sp|P07665|SRYB_DROME Serendipity locus protein beta OS=Drosophila melanogaster OX=7227 GN=Sry-beta PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 7.1 0.015 36 35 63 .. 256 295 .. 55 299 .. 0.89 2 ? -3.5 0.0 5.7 1.3e+04 56 63 .. 317 324 .. 317 346 .. 0.57 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.015 SS----S...........CHHTTEECCCCEEEETTTTEEE CS Trm112p 35 kekpedy...........ellleldieegeLvCpncgraY 63 k+++++ + l+++d ee++L+C+ c++ + sp|P07665|SRYB_DROME 256 KYQCDKCgerfslswlmyNHLMRHDAEENALICEVCHQQF 295 34444447778888888866****************9876 PP == domain 2 score: -3.5 bits; conditional E-value: 5.7 ETTTTEEE CS Trm112p 56 CpncgraY 63 Cp+c + sp|P07665|SRYB_DROME 317 CPDCEKSF 324 44443333 PP >> sp|M9MRI4|TRIM9_DROME E3 ubiquitin-protein ligase TRIM9 OS=Drosophila melanogaster OX=7227 GN=Trim9 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.1 0.047 1.1e+02 50 63 .. 1 14 [. 1 17 [. 0.90 2 ? 5.5 2.7 0.0088 20 8 63 .. 160 221 .. 158 222 .. 0.68 3 ? -1.2 0.0 1 2.4e+03 9 48 .. 294 338 .. 291 398 .. 0.58 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.047 CCCEEEETTTTEEE CS Trm112p 50 eegeLvCpncgraY 63 +e eL Cp c++ Y sp|M9MRI4|TRIM9_DROME 1 MEDELRCPTCKQLY 14 6899*******999 PP == domain 2 score: 5.5 bits; conditional E-value: 0.0088 -B-TTTHH..........C-.-HHHHHHHHH.TT---.S-SS----SCHHTTEECCCCEEEETTTTEEE CS Trm112p 8 LaCpackg..........pL.dwealvevaa.lglne.lpkekpedyellleldieegeLvCpncgraY 63 L+Cp+c++ L + a+ + + e l+ +++e +d + +L+C+ c + Y sp|M9MRI4|TRIM9_DROME 160 LTCPLCRKlvffddggvrNLpTYRAMEAIVDrFCAREaLRCQMCE-------TDPKVASLICEQCEIRY 221 89*****97777777666554444444444444444445555555.......999**********9998 PP == domain 3 score: -1.2 bits; conditional E-value: 1 B-TTTHHC-..-HHHHHHHHHTT---S-SS----S...........CHHTTEE CS Trm112p 9 aCpackgpL..dwealvevaalglnelpkekpedy...........ellleld 48 +C a k++L ++ +l+e ++ ++e++ e ++e++ sp|M9MRI4|TRIM9_DROME 294 TCKAQKTELshNLQ--------QLSEKARSTTEFIqrlkgmsdkvtESCMEFE 338 57777776633112........2222222333333444444444444444443 PP >> tr|B6VQ99|B6VQ99_DROME Neuroectoderm-expressed 2, isoform A OS=Drosophila melanogaster OX=7227 GN=Neu2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.8 0.0035 8.1 41 63 .. 180 212 .. 114 215 .. 0.78 2 ? 2.8 0.0 0.059 1.3e+02 45 66 .. 222 243 .. 212 245 .. 0.86 3 ? -1.3 0.3 1.1 2.6e+03 23 23 .. 317 317 .. 274 361 .. 0.58 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0035 S..........CHHTTEECCCCEEEETTTTEEE CS Trm112p 41 y..........ellleldieegeLvCpncgraY 63 ++ +++++ +g+L Cp c+ ++ tr|B6VQ99|B6VQ99_DROME 180 CprsftaghhlKAHIQMHERRGSLRCPYCQKCF 212 2566667777766699*************9888 PP == domain 2 score: 2.8 bits; conditional E-value: 0.059 TTEECCCCEEEETTTTEEEEEE CS Trm112p 45 leldieegeLvCpncgraYpIk 66 l ++ +e ++ C+ c + ++ tr|B6VQ99|B6VQ99_DROME 222 LATHTDETQFKCSQCSKSFQVE 243 56899***********999886 PP == domain 3 score: -1.3 bits; conditional E-value: 1.1 H CS Trm112p 23 v 23 + tr|B6VQ99|B6VQ99_DROME 317 S 317 1 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (68 nodes) Target sequences: 13786 (7394964 residues searched) Passed MSV filter: 578 (0.0419266); expected 275.7 (0.02) Passed bias filter: 434 (0.0314812); expected 275.7 (0.02) Passed Vit filter: 52 (0.00377194); expected 13.8 (0.001) Passed Fwd filter: 10 (0.000725374); expected 0.1 (1e-05) Initial search space (Z): 13786 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.11u 0.01s 00:00:00.12 Elapsed: 00:00:00.05 # Mc/sec: 10057.15 // [ok]