# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Trm112p.hmm.txt
# target sequence database: proteomes/Drosophila_melanogaster.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Trm112p [M=68]
Accession: PF03966.15
Description: Trm112p-like protein
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
4.3e-19 68.5 0.0 5.3e-19 68.2 0.0 1.1 1 sp|Q9VP65|TR112_DROME Multifunctional methyltransferase sub
------ inclusion threshold ------
0.17 12.1 6.0 0.74 10.1 0.4 4.1 3 tr|A8DYD1|A8DYD1_DROME Combgap, isoform L OS=Drosophila mela
0.21 11.8 6.9 27 5.0 0.2 4.5 4 tr|Q95RQ8|Q95RQ8_DROME LD15650p OS=Drosophila melanogaster O
1.4 9.2 9.9 36 4.7 7.1 3.6 2 sp|P07665|SRYB_DROME Serendipity locus protein beta OS=Dro
2.5 8.4 7.5 20 5.5 2.7 3.4 3 sp|M9MRI4|TRIM9_DROME E3 ubiquitin-protein ligase TRIM9 OS=
5.2 7.4 7.6 8.1 6.7 0.8 3.7 3 tr|B6VQ99|B6VQ99_DROME Neuroectoderm-expressed 2, isoform A
Domain annotation for each sequence (and alignments):
>> sp|Q9VP65|TR112_DROME Multifunctional methyltransferase subunit TRM112-like protein OS=Drosophila melanogaster OX=72
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 68.2 0.0 2.3e-22 5.3e-19 1 68 [] 2 113 .. 2 113 .. 0.98
Alignments for each domain:
== domain 1 score: 68.2 bits; conditional E-value: 2.3e-22
BTGGCCC-B-TTTHH.....C-..........................-HHHHHHHHH.TT---.S-SS----S...........CHH CS
Trm112p 1 kllllniLaCpackg.....pL..........................dwealvevaa.lglne.lpkekpedy...........ell 44
kl ++n+L++ a+kg pL dw+a++ +a+ ++l+e +p+ +pe++ +ll
sp|Q9VP65|TR112_DROME 2 KLSTYNFLTSVAIKGvkvgfPLkltinkkevvesefnptfverilpklDWSAVYGAAQvAELTEdIPAVQPENIvenelllqklhHLL 89
6889****************8899**************************************************************** PP
TTEECCCCEEEETTTTEEEEEETT CS
Trm112p 45 leldieegeLvCpncgraYpIkdG 68
+e+d++eg+L Cp++gr++pI+dG
sp|Q9VP65|TR112_DROME 90 FEIDVLEGQLECPETGRVFPISDG 113
***********************9 PP
>> tr|A8DYD1|A8DYD1_DROME Combgap, isoform L OS=Drosophila melanogaster OX=7227 GN=cg PE=1 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.1 0.4 0.00032 0.74 41 66 .. 353 388 .. 321 389 .. 0.69
2 ? -0.5 0.4 0.65 1.5e+03 54 64 .. 432 442 .. 396 442 .. 0.66
3 ? 1.4 0.0 0.17 3.9e+02 53 63 .. 572 582 .. 526 584 .. 0.85
Alignments for each domain:
== domain 1 score: 10.1 bits; conditional E-value: 0.00032
S............CHHTTEECCCCEEEETTTTEEEEEE CS
Trm112p 41 y............ellleldieegeLvCpncgraYpIk 66
+ +++ e +vC +cgra+p k
tr|A8DYD1|A8DYD1_DROME 353 CkksftlkhhlltH--SRVHSRERPFVCQECGRAFPLK 388
33445555434331..357888899***********76 PP
== domain 2 score: -0.5 bits; conditional E-value: 0.65
EEETTTTEEEE CS
Trm112p 54 LvCpncgraYp 64
+vC +cg +p
tr|A8DYD1|A8DYD1_DROME 432 FVCAECGASFP 442
47777777776 PP
== domain 3 score: 1.4 bits; conditional E-value: 0.17
EEEETTTTEEE CS
Trm112p 53 eLvCpncgraY 63
++vC++cg a+
tr|A8DYD1|A8DYD1_DROME 572 QFVCRECGSAF 582
79******998 PP
>> tr|Q95RQ8|Q95RQ8_DROME LD15650p OS=Drosophila melanogaster OX=7227 GN=pita PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.4 0.0 2.6 6e+03 33 58 .. 127 162 .. 112 163 .. 0.64
2 ? 3.4 0.0 0.039 90 49 65 .. 281 297 .. 244 299 .. 0.79
3 ? 3.0 1.0 0.05 1.2e+02 41 63 .. 459 493 .. 371 494 .. 0.80
4 ? 5.0 0.2 0.012 27 8 51 .. 511 560 .. 507 564 .. 0.75
Alignments for each domain:
== domain 1 score: -2.4 bits; conditional E-value: 2.6
S-SS----S..............CHHTTEECCCCEEEETT CS
Trm112p 33 lpkekpedy..............ellleldieegeLvCpn 58
p+e+p++ + ++++e ++v p+
tr|Q95RQ8|Q95RQ8_DROME 127 EPSETPKKLlntmaksssqviieD----VQVLESAMVTPR 162
455666655666677777644432....677778888776 PP
== domain 2 score: 3.4 bits; conditional E-value: 0.039
CCCCEEEETTTTEEEEE CS
Trm112p 49 ieegeLvCpncgraYpI 65
+ + ++ Cp+c r +p
tr|Q95RQ8|Q95RQ8_DROME 281 VATDVFPCPDCERSFPL 297
5567788********96 PP
== domain 3 score: 3.0 bits; conditional E-value: 0.05
S............CHHTTEECCCCEEEETTTTEEE CS
Trm112p 41 y............ellleldieegeLvCpncgraY 63
+l ++ + ++vC++c+ Y
tr|Q95RQ8|Q95RQ8_DROME 459 ChksymlshhlsrHLRTHTQTSDASFVCSECKVSY 493
144455555577755555888889********999 PP
== domain 4 score: 5.0 bits; conditional E-value: 0.012
-B-TTTHHC-.-HHHHHHHHH.TT---.S-SS----S...CHHTTEECCC CS
Trm112p 8 LaCpackgpL.dwealvevaa.lglne.lpkekpedy...ellleldiee 51
L+Cp+c+++ d +++ + +++e + e ++++ + +l+ +ie+
tr|Q95RQ8|Q95RQ8_DROME 511 LKCPMCRKQIeDIDSVESHMDqHKQSErHACEFCDHIfltQKCLQRHIED 560
9*******885556666666667777777777777779987788888876 PP
>> sp|P07665|SRYB_DROME Serendipity locus protein beta OS=Drosophila melanogaster OX=7227 GN=Sry-beta PE=1 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 4.7 7.1 0.015 36 35 63 .. 256 295 .. 55 299 .. 0.89
2 ? -3.5 0.0 5.7 1.3e+04 56 63 .. 317 324 .. 317 346 .. 0.57
Alignments for each domain:
== domain 1 score: 4.7 bits; conditional E-value: 0.015
SS----S...........CHHTTEECCCCEEEETTTTEEE CS
Trm112p 35 kekpedy...........ellleldieegeLvCpncgraY 63
k+++++ + l+++d ee++L+C+ c++ +
sp|P07665|SRYB_DROME 256 KYQCDKCgerfslswlmyNHLMRHDAEENALICEVCHQQF 295
34444447778888888866****************9876 PP
== domain 2 score: -3.5 bits; conditional E-value: 5.7
ETTTTEEE CS
Trm112p 56 CpncgraY 63
Cp+c +
sp|P07665|SRYB_DROME 317 CPDCEKSF 324
44443333 PP
>> sp|M9MRI4|TRIM9_DROME E3 ubiquitin-protein ligase TRIM9 OS=Drosophila melanogaster OX=7227 GN=Trim9 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 3.1 0.1 0.047 1.1e+02 50 63 .. 1 14 [. 1 17 [. 0.90
2 ? 5.5 2.7 0.0088 20 8 63 .. 160 221 .. 158 222 .. 0.68
3 ? -1.2 0.0 1 2.4e+03 9 48 .. 294 338 .. 291 398 .. 0.58
Alignments for each domain:
== domain 1 score: 3.1 bits; conditional E-value: 0.047
CCCEEEETTTTEEE CS
Trm112p 50 eegeLvCpncgraY 63
+e eL Cp c++ Y
sp|M9MRI4|TRIM9_DROME 1 MEDELRCPTCKQLY 14
6899*******999 PP
== domain 2 score: 5.5 bits; conditional E-value: 0.0088
-B-TTTHH..........C-.-HHHHHHHHH.TT---.S-SS----SCHHTTEECCCCEEEETTTTEEE CS
Trm112p 8 LaCpackg..........pL.dwealvevaa.lglne.lpkekpedyellleldieegeLvCpncgraY 63
L+Cp+c++ L + a+ + + e l+ +++e +d + +L+C+ c + Y
sp|M9MRI4|TRIM9_DROME 160 LTCPLCRKlvffddggvrNLpTYRAMEAIVDrFCAREaLRCQMCE-------TDPKVASLICEQCEIRY 221
89*****97777777666554444444444444444445555555.......999**********9998 PP
== domain 3 score: -1.2 bits; conditional E-value: 1
B-TTTHHC-..-HHHHHHHHHTT---S-SS----S...........CHHTTEE CS
Trm112p 9 aCpackgpL..dwealvevaalglnelpkekpedy...........ellleld 48
+C a k++L ++ +l+e ++ ++e++ e ++e++
sp|M9MRI4|TRIM9_DROME 294 TCKAQKTELshNLQ--------QLSEKARSTTEFIqrlkgmsdkvtESCMEFE 338
57777776633112........2222222333333444444444444444443 PP
>> tr|B6VQ99|B6VQ99_DROME Neuroectoderm-expressed 2, isoform A OS=Drosophila melanogaster OX=7227 GN=Neu2 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 6.7 0.8 0.0035 8.1 41 63 .. 180 212 .. 114 215 .. 0.78
2 ? 2.8 0.0 0.059 1.3e+02 45 66 .. 222 243 .. 212 245 .. 0.86
3 ? -1.3 0.3 1.1 2.6e+03 23 23 .. 317 317 .. 274 361 .. 0.58
Alignments for each domain:
== domain 1 score: 6.7 bits; conditional E-value: 0.0035
S..........CHHTTEECCCCEEEETTTTEEE CS
Trm112p 41 y..........ellleldieegeLvCpncgraY 63
++ +++++ +g+L Cp c+ ++
tr|B6VQ99|B6VQ99_DROME 180 CprsftaghhlKAHIQMHERRGSLRCPYCQKCF 212
2566667777766699*************9888 PP
== domain 2 score: 2.8 bits; conditional E-value: 0.059
TTEECCCCEEEETTTTEEEEEE CS
Trm112p 45 leldieegeLvCpncgraYpIk 66
l ++ +e ++ C+ c + ++
tr|B6VQ99|B6VQ99_DROME 222 LATHTDETQFKCSQCSKSFQVE 243
56899***********999886 PP
== domain 3 score: -1.3 bits; conditional E-value: 1.1
H CS
Trm112p 23 v 23
+
tr|B6VQ99|B6VQ99_DROME 317 S 317
1 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (68 nodes)
Target sequences: 13786 (7394964 residues searched)
Passed MSV filter: 578 (0.0419266); expected 275.7 (0.02)
Passed bias filter: 434 (0.0314812); expected 275.7 (0.02)
Passed Vit filter: 52 (0.00377194); expected 13.8 (0.001)
Passed Fwd filter: 10 (0.000725374); expected 0.1 (1e-05)
Initial search space (Z): 13786 [actual number of targets]
Domain search space (domZ): 6 [number of targets reported over threshold]
# CPU time: 0.11u 0.01s 00:00:00.12 Elapsed: 00:00:00.05
# Mc/sec: 10057.15
//
[ok]