# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Trm112p.hmm.txt # target sequence database: proteomes/Homo_sapiens.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Trm112p [M=68] Accession: PF03966.15 Description: Trm112p-like protein Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-14 56.2 0.0 2.3e-14 55.9 0.0 1.1 1 sp|Q9UI30|TR112_HUMAN tRNA methyltransferase 112 homolog O 3.8e-14 55.2 0.0 4.6e-14 55.0 0.0 1.1 1 tr|M0R242|M0R242_HUMAN Uncharacterized protein OS=Homo sapi 1.6e-12 50.1 0.0 2e-12 49.7 0.0 1.1 1 tr|J3KNG5|J3KNG5_HUMAN tRNA methyltransferase 112 homolog O 6.4e-11 44.9 0.0 8.3e-11 44.5 0.0 1.1 1 tr|F5GYQ2|F5GYQ2_HUMAN tRNA methyltransferase 112 homolog O 8.3e-08 34.9 0.1 2.7e-07 33.3 0.1 1.9 1 sp|Q96I23|PREY_HUMAN Protein preY, mitochondrial OS=Homo 5e-05 26.0 9.0 0.22 14.4 0.3 4.6 3 sp|P0C7V5|ZN812_HUMAN Putative zinc finger protein 812 OS= 0.00044 23.0 0.0 0.00057 22.6 0.0 1.1 1 tr|F5GX77|F5GX77_HUMAN tRNA methyltransferase 112 homolog O 0.0028 20.4 8.7 3.8 10.4 0.1 4.7 2 tr|B4E2Q8|B4E2Q8_HUMAN Zinc finger protein 561 OS=Homo sapi 0.0056 19.4 9.5 4.9 10.0 0.1 5.2 3 tr|A8KAD9|A8KAD9_HUMAN Zinc finger protein 561 OS=Homo sapi ------ inclusion threshold ------ 0.012 18.4 0.2 9.6 9.1 0.0 4.0 4 sp|C9JLR9|CK095_HUMAN Uncharacterized protein C11orf95 OS= 0.015 18.1 9.8 6.2 9.7 0.1 5.1 3 sp|Q8N587|ZN561_HUMAN Zinc finger protein 561 OS=Homo sapi 0.14 15.0 1.8 0.59 13.0 1.8 2.2 1 sp|O00635|TRI38_HUMAN Tripartite motif-containing protein 0.16 14.8 0.5 0.16 14.8 0.5 2.4 2 tr|H0Y9S1|H0Y9S1_HUMAN PR domain zinc finger protein 5 (Fra 0.31 13.9 10.4 1.3e+02 5.5 0.0 5.5 4 tr|F5H1K2|F5H1K2_HUMAN Zinc finger protein 324A OS=Homo sap 0.33 13.8 0.0 0.52 13.1 0.0 1.3 1 tr|H7C2W1|H7C2W1_HUMAN D-beta-hydroxybutyrate dehydrogenase 0.43 13.4 9.2 1.7e+02 5.1 0.0 5.3 4 tr|M0R1C8|M0R1C8_HUMAN Zinc finger protein 324A (Fragment) 0.49 13.2 1.4 1.4 11.8 1.4 1.8 1 tr|Q5SPU2|Q5SPU2_HUMAN Tripartite motif-containing protein 0.57 13.0 0.2 1.7 11.5 0.2 1.9 1 sp|Q9Y2E6-2|DTX4_HUMAN Isoform 2 of E3 ubiquitin-protein li 0.6 12.9 7.4 2.5e+02 4.6 0.0 5.1 4 sp|O75467|Z324A_HUMAN Zinc finger protein 324A OS=Homo sap 0.62 12.9 0.2 0.62 12.9 0.2 4.5 4 tr|Q0VAI9|Q0VAI9_HUMAN PR domain zinc finger protein 5 OS=H 0.71 12.7 1.1 6.4 9.7 0.0 2.6 2 tr|H0Y3W3|H0Y3W3_HUMAN Exportin-5 (Fragment) OS=Homo sapien 0.8 12.5 0.2 2.2 11.1 0.2 1.8 1 sp|Q9Y2E6|DTX4_HUMAN E3 ubiquitin-protein ligase DTX4 OS= 0.8 12.5 6.1 1.3 11.8 6.1 1.4 1 tr|D6RAL3|D6RAL3_HUMAN E3 ubiquitin-protein ligase SH3RF1 ( 0.83 12.5 0.2 0.83 12.5 0.2 5.6 5 sp|Q9NQX1|PRDM5_HUMAN PR domain zinc finger protein 5 OS=H 0.84 12.5 0.1 0.84 12.5 0.1 5.4 5 sp|Q9NQX1-2|PRDM5_HUMAN Isoform 2 of PR domain zinc finger p 0.93 12.3 5.5 1.6 11.6 5.5 1.4 1 tr|D6RHX5|D6RHX5_HUMAN E3 ubiquitin-protein ligase SH3RF1 ( 1.6 11.6 2.6 61 6.5 0.5 3.5 3 sp|O43623|SNAI2_HUMAN Zinc finger protein SNAI2 OS=Homo sa 1.6 11.6 18.5 44 7.0 0.1 6.5 4 tr|H7BXP3|H7BXP3_HUMAN Zinc finger protein 786 OS=Homo sapi 2.4 11.0 18.5 47 6.9 0.1 6.5 4 tr|B4DMI1|B4DMI1_HUMAN Zinc finger protein 786 OS=Homo sapi 2.7 10.9 3.6 3.8 10.4 1.4 2.3 2 tr|A2AE48|A2AE48_HUMAN Tripartite motif-containing protein 3 10.7 18.4 51 6.8 0.1 6.5 4 sp|Q8N393|ZN786_HUMAN Zinc finger protein 786 OS=Homo sapi 3.2 10.6 13.6 11 8.9 1.2 5.4 2 sp|Q8NEM1|ZN680_HUMAN Zinc finger protein 680 OS=Homo sapi 3.3 10.6 0.0 3.3 10.6 0.0 3.8 3 tr|F5H1B4|F5H1B4_HUMAN Zinc finger protein 562 OS=Homo sapi 3.3 10.6 3.9 3.2e+02 4.2 1.3 3.8 3 sp|Q9HBF4-2|ZFYV1_HUMAN Isoform 2 of Zinc finger FYVE domain 3.5 10.5 5.9 34 7.3 0.8 3.5 2 tr|J3QQL1|J3QQL1_HUMAN Zinc finger protein 236 (Fragment) O 3.7 10.4 10.7 1.7e+02 5.1 0.0 5.6 4 tr|B4DNX9|B4DNX9_HUMAN Zinc finger protein 460 OS=Homo sapi 6.9 9.6 5.1 2 11.2 1.3 2.2 1 sp|O75437-2|ZN254_HUMAN Isoform 2 of Zinc finger protein 254 8.8 9.2 9.4 1e+02 5.8 0.2 3.7 2 sp|Q9C026-5|TRIM9_HUMAN Isoform 5 of E3 ubiquitin-protein li 9.7 9.1 5.5 25 7.8 5.5 1.7 1 sp|Q7Z6J0-3|SH3R1_HUMAN Isoform 2 of E3 ubiquitin-protein li Domain annotation for each sequence (and alignments): >> sp|Q9UI30|TR112_HUMAN tRNA methyltransferase 112 homolog OS=Homo sapiens GN=TRMT112 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.9 0.0 1e-17 2.3e-14 1 68 [] 2 112 .. 2 112 .. 0.98 Alignments for each domain: == domain 1 score: 55.9 bits; conditional E-value: 1e-17 BTGGCCC-B-TTTHH......C-..........................-HHHHHHHHH.TT---S-SS----S...........CHH CS Trm112p 1 kllllniLaCpackg......pL..........................dwealvevaa.lglnelpkekpedy...........ell 44 kll++n+L+++ ++g pL +w+a++e+a l+l ++pk + e y +ll sp|Q9UI30|TR112_HUMAN 2 KLLTHNLLSSH-VRGvgsrgfPLrlqatevricpvefnpnfvarmipkvEWSAFLEAADnLRLIQVPKGPVEGYeeneeflrtmhHLL 88 789********.*********9999*************************************************************** PP TTEECCCCEEEETTTTEEEEEETT CS Trm112p 45 leldieegeLvCpncgraYpIkdG 68 le++++eg+L+Cp+ gr +pI+ G sp|Q9UI30|TR112_HUMAN 89 LEVEVIEGTLQCPESGRMFPISRG 112 *********************988 PP >> tr|M0R242|M0R242_HUMAN Uncharacterized protein OS=Homo sapiens PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.0 0.0 2e-17 4.6e-14 1 68 [] 2 122 .. 2 122 .. 0.98 Alignments for each domain: == domain 1 score: 55.0 bits; conditional E-value: 2e-17 BTGGCCC-B-TTTHH......C-....................................-HHHHHHHHH.TT---S-SS----S... CS Trm112p 1 kllllniLaCpackg......pL....................................dwealvevaa.lglnelpkekpedy... 41 kll++n+L+++ ++g pL +w+a++e+a l+l ++pk + e y tr|M0R242|M0R242_HUMAN 2 KLLTHNLLSSH-VRGmgsrgfPLclqatevricpvefnpqfmwhhtwhvsyvvhmipkvEWSAFLEAADsLRLIQMPKGPVEGYeen 87 789********.9**9*****99**************************************************************** PP ........CHHTTEECCCCEEEETTTTEEEEEETT CS Trm112p 42 ........ellleldieegeLvCpncgraYpIkdG 68 +llle++++eg+L+Cp+ gr +pI+ G tr|M0R242|M0R242_HUMAN 88 eeflrtmhHLLLEVEVIEGTLQCPESGRMFPISRG 122 ********************************988 PP >> tr|J3KNG5|J3KNG5_HUMAN tRNA methyltransferase 112 homolog OS=Homo sapiens GN=TRMT112 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.7 0.0 8.7e-16 2e-12 1 68 [] 2 107 .. 2 107 .. 0.96 Alignments for each domain: == domain 1 score: 49.7 bits; conditional E-value: 8.7e-16 BTGGCCC-B-TTTHH......C-..........................-HHHHHHHHHTT---S-SS----S...........CHH CS Trm112p 1 kllllniLaCpackg......pL..........................dwealvevaalglnelpkekpedy...........ell 44 kll++n+L+++ ++g pL +w+a++e+a +pk + e y +ll tr|J3KNG5|J3KNG5_HUMAN 2 KLLTHNLLSSH-VRGvgsrgfPLrlqatevricpvefnpnfvarmipkvEWSAFLEAAD----NVPKGPVEGYeeneeflrtmhHLL 83 789********.*********9999*********************************7....8999999999999*********** PP TTEECCCCEEEETTTTEEEEEETT CS Trm112p 45 leldieegeLvCpncgraYpIkdG 68 le++++eg+L+Cp+ gr +pI+ G tr|J3KNG5|J3KNG5_HUMAN 84 LEVEVIEGTLQCPESGRMFPISRG 107 *********************988 PP >> tr|F5GYQ2|F5GYQ2_HUMAN tRNA methyltransferase 112 homolog OS=Homo sapiens GN=TRMT112 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.5 0.0 3.7e-14 8.3e-11 18 68 .] 6 68 .. 4 68 .. 0.98 Alignments for each domain: == domain 1 score: 44.5 bits; conditional E-value: 3.7e-14 -HHHHHHHHH.TT---S-SS----S...........CHHTTEECCCCEEEETTTTEEEEEETT CS Trm112p 18 dwealvevaa.lglnelpkekpedy...........ellleldieegeLvCpncgraYpIkdG 68 +w+a++e+a l+l ++pk + e y +llle++++eg+L+Cp+ gr +pI+ G tr|F5GYQ2|F5GYQ2_HUMAN 6 EWSAFLEAADnLRLIQVPKGPVEGYeeneeflrtmhHLLLEVEVIEGTLQCPESGRMFPISRG 68 7***********************************************************988 PP >> sp|Q96I23|PREY_HUMAN Protein preY, mitochondrial OS=Homo sapiens GN=PYURF PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 0.1 1.2e-10 2.7e-07 1 68 [] 51 90 .. 51 90 .. 0.96 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 1.2e-10 BTGGCCC-B-TTTHHC--HHHHHHHHHTT---S-SS----SCHHTTEECCCCEEEETTTTEEEEEETT CS Trm112p 1 kllllniLaCpackgpLdwealvevaalglnelpkekpedyellleldieegeLvCpncgraYpIkdG 68 ++ ll++L+Cp+ k+pL ++ ++eL++++ g+aYpI dG sp|Q96I23|PREY_HUMAN 51 DPALLEFLVCPLSKKPL------------------------R----YEASTNELINEELGIAYPIIDG 90 678**************........................5....9********************9 PP >> sp|P0C7V5|ZN812_HUMAN Putative zinc finger protein 812 OS=Homo sapiens GN=ZNF812 PE=5 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.1 0.0018 4.1 41 64 .. 226 259 .. 166 259 .. 0.76 2 ? 0.4 0.6 2.2 5e+03 41 63 .. 310 342 .. 292 343 .. 0.56 3 ! 14.4 0.3 9.5e-05 0.22 10 65 .. 391 428 .. 354 430 .. 0.78 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.0018 S..........CHHTTEECCCCEEEETTTTEEEE CS Trm112p 41 y..........ellleldieegeLvCpncgraYp 64 + ++ +++++ e ++ C++cgr ++ sp|P0C7V5|ZN812_HUMAN 226 HgksftnfsqlSAHVKIHKGEKSFECKECGRSFR 259 2555567777766799***************996 PP == domain 2 score: 0.4 bits; conditional E-value: 2.2 S............CHHTTEECCCCEEEETTTTEEE CS Trm112p 41 y............ellleldieegeLvCpncgraY 63 + ++ + e +C++cg a+ sp|P0C7V5|ZN812_HUMAN 310 CgqaftqytglaiH--IRNHTGEKHYQCKECGKAF 342 33444444444222..4455555666777777776 PP == domain 3 score: 14.4 bits; conditional E-value: 9.5e-05 -TTTHHC--HHHHHHHHHTT---S-SS----S..........CHHTTEECCCCEEEETTTTEEEEE CS Trm112p 10 CpackgpLdwealvevaalglnelpkekpedy..........ellleldieegeLvCpncgraYpI 65 C + ++ l+++ e +L+C++cg a+ + sp|P0C7V5|ZN812_HUMAN 391 CKI----------------------------CgkaflyssplNVHLQTHTREKALICKECGKAFAV 428 333............................033344444446779******************88 PP >> tr|F5GX77|F5GX77_HUMAN tRNA methyltransferase 112 homolog OS=Homo sapiens GN=TRMT112 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 2.5e-07 0.00057 1 47 [. 2 91 .. 2 94 .. 0.94 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 2.5e-07 BTGGCCC-B-TTTHH......C-..........................-HHHHHHHHH.TT---S-SS----S...........CHHT CS Trm112p 1 kllllniLaCpackg......pL..........................dwealvevaa.lglnelpkekpedy...........elll 45 kll++n+L+++ ++g pL +w+a++e+a l+l ++pk + e y +lll tr|F5GX77|F5GX77_HUMAN 2 KLLTHNLLSSH-VRGvgsrgfPLrlqatevricpvefnpnfvarmipkvEWSAFLEAADnLRLIQVPKGPVEGYeeneeflrtmhHLLL 89 789********.*********9999*************************************************999988888888888 PP TE CS Trm112p 46 el 47 e+ tr|F5GX77|F5GX77_HUMAN 90 EV 91 76 PP >> tr|B4E2Q8|B4E2Q8_HUMAN Zinc finger protein 561 OS=Homo sapiens GN=ZNF561 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.1 0.0017 3.8 41 64 .. 125 155 .. 79 155 .. 0.78 2 ? 6.5 2.5 0.027 61 41 65 .. 293 324 .. 174 326 .. 0.84 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.0017 S.......CHHTTEECCCCEEEETTTTEEEE CS Trm112p 41 y.......ellleldieegeLvCpncgraYp 64 ++ +++++ e ++ C++cgr ++ tr|B4E2Q8|B4E2Q8_HUMAN 125 SftnfsqlYAPVKTHKGEKSFECKECGRSFR 155 1555666667789***************996 PP == domain 2 score: 6.5 bits; conditional E-value: 0.027 S.......CHHTTEECCCCEEEETTTTEEEEE CS Trm112p 41 y.......ellleldieegeLvCpncgraYpI 65 + ++ l+++ e +vC++cg a+ + tr|B4E2Q8|B4E2Q8_HUMAN 293 AflyssrlNVHLRTHTGEKPFVCKECGKAFAV 324 04445555556889999999999999999987 PP >> tr|A8KAD9|A8KAD9_HUMAN Zinc finger protein 561 OS=Homo sapiens GN=ZNF561 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.1 8.5 1.9e+04 56 64 .. 51 59 .. 50 59 .. 0.91 2 ! 10.0 0.1 0.0022 4.9 41 64 .. 192 222 .. 149 222 .. 0.77 3 ? 6.7 1.9 0.024 54 41 65 .. 360 391 .. 241 393 .. 0.84 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 8.5 ETTTTEEEE CS Trm112p 56 CpncgraYp 64 C+ncg +++ tr|A8KAD9|A8KAD9_HUMAN 51 CKNCGEVFR 59 ******995 PP == domain 2 score: 10.0 bits; conditional E-value: 0.0022 S.......CHHTTEECCCCEEEETTTTEEEE CS Trm112p 41 y.......ellleldieegeLvCpncgraYp 64 ++ +++++ e ++ C++cgr ++ tr|A8KAD9|A8KAD9_HUMAN 192 SftnfsqlYAPVKTHKGEKSFECKECGRSFR 222 1555556667789***************996 PP == domain 3 score: 6.7 bits; conditional E-value: 0.024 S.......CHHTTEECCCCEEEETTTTEEEEE CS Trm112p 41 y.......ellleldieegeLvCpncgraYpI 65 + ++ l+++ e +vC++cg a+ + tr|A8KAD9|A8KAD9_HUMAN 360 AflyssrlNVHLRTHTGEKPFVCKECGKAFAV 391 04445555556889999999999999999987 PP >> sp|C9JLR9|CK095_HUMAN Uncharacterized protein C11orf95 OS=Homo sapiens GN=C11orf95 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 3.2 7.3e+03 41 60 .. 104 130 .. 78 133 .. 0.76 2 ? 9.1 0.0 0.0042 9.6 39 64 .. 257 293 .. 206 293 .. 0.77 3 ? 1.8 0.0 0.78 1.8e+03 41 60 .. 417 443 .. 383 447 .. 0.77 4 ? 1.1 0.0 1.4 3.1e+03 41 60 .. 572 606 .. 544 618 .. 0.76 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 3.2 S.......CHHTTEECCCCEEEETTTT CS Trm112p 41 y.......ellleldieegeLvCpncg 60 y e l+ ++ + +vC cg sp|C9JLR9|CK095_HUMAN 104 YyhdhwrlEYLMDFNPARHGMVCMVCG 130 255556778899999********9998 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0042 --S...........CHHTTEECCCCEEEETTTTEEEE CS Trm112p 39 edy...........ellleldieegeLvCpncgraYp 64 e++ e l+ +d + LvC +cgra p sp|C9JLR9|CK095_HUMAN 257 ERRlkeslqnwfraECLMDYDPRGNRLVCMACGRALP 293 3334444467788899******************976 PP == domain 3 score: 1.8 bits; conditional E-value: 0.78 S.......CHHTTEECCCCEEEETTTT CS Trm112p 41 y.......ellleldieegeLvCpncg 60 + e l+eld + LvC cg sp|C9JLR9|CK095_HUMAN 417 HpqerwrlEYLMELDGGRRGLVCGVCG 443 03333588889*************998 PP == domain 4 score: 1.1 bits; conditional E-value: 1.4 S...............CHHTTEECCCCEEEETTTT CS Trm112p 41 y...............ellleldieegeLvCpncg 60 + e l+ +d + LvC cg sp|C9JLR9|CK095_HUMAN 572 PrsreqrrnyqprwrgEYLMDYDGSRRGLVCMVCG 606 03345667777778887788888888999998887 PP >> sp|Q8N587|ZN561_HUMAN Zinc finger protein 561 OS=Homo sapiens GN=ZNF561 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.1 0.0027 6.2 41 64 .. 261 291 .. 220 291 .. 0.77 2 ? -0.0 0.4 3 6.7e+03 56 63 .. 339 346 .. 310 377 .. 0.63 3 ? 7.9 0.1 0.01 23 41 65 .. 432 460 .. 378 462 .. 0.76 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.0027 S.......CHHTTEECCCCEEEETTTTEEEE CS Trm112p 41 y.......ellleldieegeLvCpncgraYp 64 ++ +++++ e ++ C++cgr ++ sp|Q8N587|ZN561_HUMAN 261 SftnfsqlYAPVKTHKGEKSFECKECGRSFR 291 1555556666789***************996 PP == domain 2 score: -0.0 bits; conditional E-value: 3 ETTTTEEE CS Trm112p 56 CpncgraY 63 C++cg+a+ sp|Q8N587|ZN561_HUMAN 339 CKECGQAF 346 44444444 PP == domain 3 score: 7.9 bits; conditional E-value: 0.01 S....CHHTTEECCCCEEEETTTTEEEEE CS Trm112p 41 y....ellleldieegeLvCpncgraYpI 65 y ++ l+++ e +vC++cg a+ + sp|Q8N587|ZN561_HUMAN 432 YssrlNVHLRTHTGEKPFVCKECGKAFAV 460 04445556889999999999999999987 PP >> sp|O00635|TRI38_HUMAN Tripartite motif-containing protein 38 OS=Homo sapiens GN=TRIM38 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 1.8 0.00026 0.59 7 62 .. 56 118 .. 50 118 .. 0.64 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00026 C-B-TTTHHC-.........-HHHHHHHHHTT---.S-SS----S.CHHTTEECCCCEEEETTTTEE CS Trm112p 7 iLaCpackgpL.........dwealvevaalglne.lpkekpedy.ellleldieegeLvCpncgra 62 +Cp+c+ p ++ +l+e+ + e ++ +e++ e + ++++eg+L+C +c ra sp|O00635|TRI38_HUMAN 56 TFCCPQCRAPFhmdslrpnkQLGSLIEALK----EtDQEMSCEEHgEQFHLFCEDEGQLICWRCERA 118 569******884444444444444444444....223344444448556679************996 PP >> tr|H0Y9S1|H0Y9S1_HUMAN PR domain zinc finger protein 5 (Fragment) OS=Homo sapiens GN=PRDM5 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.5 7.1e-05 0.16 41 67 .. 25 56 .. 9 56 .. 0.70 2 ? -0.4 0.2 3.8 8.5e+03 52 63 .. 76 87 .. 60 113 .. 0.67 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 7.1e-05 S.....CHHTTEECCCCEEEETTTTEEEEEET CS Trm112p 41 y.....ellleldieegeLvCpncgraYpIkd 67 + ++l++ ee e+ C+ncg +p+k+ tr|H0Y9S1|H0Y9S1_HUMAN 25 IlaehlQTLHQKPTEEKEFKCKNCGKKFPVKQ 56 13333377889999****************85 PP == domain 2 score: -0.4 bits; conditional E-value: 3.8 CEEEETTTTEEE CS Trm112p 52 geLvCpncgraY 63 +++C+ c+ + tr|H0Y9S1|H0Y9S1_HUMAN 76 RSFQCSVCNSSF 87 455555555444 PP >> tr|F5H1K2|F5H1K2_HUMAN Zinc finger protein 324A OS=Homo sapiens GN=ZNF324 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 1.4 3.2e+03 47 63 .. 27 43 .. 9 44 .. 0.79 2 ? 4.3 0.5 0.14 3.1e+02 46 63 .. 110 127 .. 63 128 .. 0.73 3 ? 4.6 0.2 0.11 2.4e+02 47 63 .. 195 211 .. 156 212 .. 0.77 4 ? 5.5 0.0 0.057 1.3e+02 47 64 .. 251 268 .. 217 268 .. 0.84 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 1.4 EECCCCEEEETTTTEEE CS Trm112p 47 ldieegeLvCpncgraY 63 l+ e ++ C++c ++ tr|F5H1K2|F5H1K2_HUMAN 27 LHAGEKSFECRACSKVF 43 678899*******9887 PP == domain 2 score: 4.3 bits; conditional E-value: 0.14 TEECCCCEEEETTTTEEE CS Trm112p 46 eldieegeLvCpncgraY 63 +++ e ++ C++cg a+ tr|F5H1K2|F5H1K2_HUMAN 110 RIHTAEKSFRCSECGKAF 127 478899*********998 PP == domain 3 score: 4.6 bits; conditional E-value: 0.11 EECCCCEEEETTTTEEE CS Trm112p 47 ldieegeLvCpncgraY 63 ++ e + Cp cgra+ tr|F5H1K2|F5H1K2_HUMAN 195 VHTGEKPFACPQCGRAF 211 445567889******99 PP == domain 4 score: 5.5 bits; conditional E-value: 0.057 EECCCCEEEETTTTEEEE CS Trm112p 47 ldieegeLvCpncgraYp 64 ++ e +vC+ cgra++ tr|F5H1K2|F5H1K2_HUMAN 251 IHTGEKPFVCTQCGRAFR 268 56667889********96 PP >> tr|H7C2W1|H7C2W1_HUMAN D-beta-hydroxybutyrate dehydrogenase, mitochondrial (Fragment) OS=Homo sapiens GN=BDH1 PE=4 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 0.00023 0.52 16 60 .. 38 80 .. 29 84 .. 0.70 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.00023 C--HHHHHHHHH.TT---.S-SS----S.CHHTTEECCCCEEEETTTT CS Trm112p 16 pLdwealvevaa.lglne.lpkekpedy.ellleldieegeLvCpncg 60 pL +++a+ + e +p++ p + +l+ e++ ++++L+Cp tr|H7C2W1|H7C2W1_HUMAN 38 PL-----IRRAKgEWERElPPAPEPAPRvHLCSEWKYLSQQLQCPQLS 80 55.....5555555555535555555557****************875 PP >> tr|M0R1C8|M0R1C8_HUMAN Zinc finger protein 324A (Fragment) OS=Homo sapiens GN=ZNF324 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 1.4 3.1e+03 47 63 .. 109 125 .. 51 126 .. 0.84 2 ? 4.0 0.3 0.17 3.8e+02 46 63 .. 192 209 .. 151 210 .. 0.73 3 ? 4.1 0.4 0.16 3.5e+02 47 63 .. 277 293 .. 230 294 .. 0.77 4 ? 5.1 0.0 0.076 1.7e+02 47 64 .. 333 350 .. 299 350 .. 0.84 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 1.4 EECCCCEEEETTTTEEE CS Trm112p 47 ldieegeLvCpncgraY 63 l+ e ++ C++c ++ tr|M0R1C8|M0R1C8_HUMAN 109 LHAGEKSFECRACSKVF 125 788899*******9887 PP == domain 2 score: 4.0 bits; conditional E-value: 0.17 TEECCCCEEEETTTTEEE CS Trm112p 46 eldieegeLvCpncgraY 63 +++ e ++ C++cg a+ tr|M0R1C8|M0R1C8_HUMAN 192 RIHTAEKSFRCSECGKAF 209 478899*********998 PP == domain 3 score: 4.1 bits; conditional E-value: 0.16 EECCCCEEEETTTTEEE CS Trm112p 47 ldieegeLvCpncgraY 63 ++ e + Cp cgra+ tr|M0R1C8|M0R1C8_HUMAN 277 VHTGEKPFACPQCGRAF 293 445567889******99 PP == domain 4 score: 5.1 bits; conditional E-value: 0.076 EECCCCEEEETTTTEEEE CS Trm112p 47 ldieegeLvCpncgraYp 64 ++ e +vC+ cgra++ tr|M0R1C8|M0R1C8_HUMAN 333 IHTGEKPFVCTQCGRAFR 350 56667889********96 PP >> tr|Q5SPU2|Q5SPU2_HUMAN Tripartite motif-containing protein 26 (Fragment) OS=Homo sapiens GN=TRIM26 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 1.4 0.00062 1.4 9 60 .. 52 125 .. 52 127 .. 0.77 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00062 B-TTTHHC-.........-HHHHHHHHH.TT---.S-SS----S...........CHHTTEECCCCEEEETTTT CS Trm112p 9 aCpackgpL.........dwealvevaa.lglne.lpkekpedy...........ellleldieegeLvCpncg 60 +Cp+ck+p ++++lve+ + l+ ++ ++ ++ e l+ +++++g+L C c+ tr|Q5SPU2|Q5SPU2_HUMAN 52 VCPLCKKPFkkenirpvwQLASLVENIErLKVDKgRQPGEVTREqqdaklcerhrEKLHYYCEDDGKLLCVMCR 125 7******66666667767667777777777777766666666668999999999*88999**********9987 PP >> sp|Q9Y2E6-2|DTX4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase DTX4 OS=Homo sapiens GN=DTX4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.2 0.00073 1.7 29 68 .] 315 370 .. 295 370 .. 0.75 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00073 T---.S-SS----S...............CHHTTEECCCCEEEETTTTEEEEEETT CS Trm112p 29 glne.lpkekpedy...............ellleldieegeLvCpncgraYpIkdG 68 g++ p kp+ + ++ ++ ++g+L+Cp c+ +Y +k G sp|Q9Y2E6-2|DTX4_HUMAN 315 GYKGpQPTVKPDLVgklsrcghvyhiyclVAMYNNGNKDGSLQCPTCKTIYGVKTG 370 555555666677667777777777777776677778889************99876 PP >> sp|O75467|Z324A_HUMAN Zinc finger protein 324A OS=Homo sapiens GN=ZNF324 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 2.2 4.9e+03 47 63 .. 250 266 .. 211 267 .. 0.82 2 ? 3.4 0.3 0.25 5.6e+02 46 63 .. 333 350 .. 287 351 .. 0.74 3 ? 3.7 0.3 0.21 4.7e+02 47 63 .. 418 434 .. 371 435 .. 0.77 4 ? 4.6 0.0 0.11 2.5e+02 47 64 .. 474 491 .. 440 491 .. 0.84 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 2.2 EECCCCEEEETTTTEEE CS Trm112p 47 ldieegeLvCpncgraY 63 l+ e ++ C++c ++ sp|O75467|Z324A_HUMAN 250 LHAGEKSFECRACSKVF 266 788899*******9887 PP == domain 2 score: 3.4 bits; conditional E-value: 0.25 TEECCCCEEEETTTTEEE CS Trm112p 46 eldieegeLvCpncgraY 63 +++ e ++ C++cg a+ sp|O75467|Z324A_HUMAN 333 RIHTAEKSFRCSECGKAF 350 478899*********998 PP == domain 3 score: 3.7 bits; conditional E-value: 0.21 EECCCCEEEETTTTEEE CS Trm112p 47 ldieegeLvCpncgraY 63 ++ e + Cp cgra+ sp|O75467|Z324A_HUMAN 418 VHTGEKPFACPQCGRAF 434 445567889******99 PP == domain 4 score: 4.6 bits; conditional E-value: 0.11 EECCCCEEEETTTTEEEE CS Trm112p 47 ldieegeLvCpncgraYp 64 ++ e +vC+ cgra++ sp|O75467|Z324A_HUMAN 474 IHTGEKPFVCTQCGRAFR 491 56667889********96 PP >> tr|Q0VAI9|Q0VAI9_HUMAN PR domain zinc finger protein 5 OS=Homo sapiens GN=PRDM5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.2 0.00027 0.62 41 67 .. 175 212 .. 128 212 .. 0.79 2 ? -1.3 0.1 7.5 1.7e+04 47 60 .. 257 270 .. 232 272 .. 0.71 3 ? 5.0 0.2 0.082 1.9e+02 28 64 .. 337 383 .. 282 384 .. 0.65 4 ? 1.6 0.8 0.91 2.1e+03 10 63 .. 403 467 .. 400 468 .. 0.64 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.00027 S...........CHHTTEECCCCEEEETTTTEEEEEET CS Trm112p 41 y...........ellleldieegeLvCpncgraYpIkd 67 ++l++ ee e+ C+ncg +p+k+ tr|Q0VAI9|Q0VAI9_HUMAN 175 SftsedilaehlQTLHQKPTEEKEFKCKNCGKKFPVKQ 212 23334445555578889999****************85 PP == domain 2 score: -1.3 bits; conditional E-value: 7.5 EECCCCEEEETTTT CS Trm112p 47 ldieegeLvCpncg 60 + + + +L+C+ c+ tr|Q0VAI9|Q0VAI9_HUMAN 257 TGDPKKKLICSVCN 270 55556899999997 PP == domain 3 score: 5.0 bits; conditional E-value: 0.082 TT---S-SS----S............CHHTTEECCCCEEEETTTTEEEE CS Trm112p 28 lglnelpkekpedy............ellleldieegeLvCpncgraYp 64 + +e +++k++ + +++ ee ++C++c+ ++ tr|Q0VAI9|Q0VAI9_HUMAN 337 VIHSEDKPYKCKLCgkgfahrnvyknH--KKTHSEERPFQCEECKALFR 383 333445666666668888888888662..579************99885 PP == domain 4 score: 1.6 bits; conditional E-value: 0.91 -TTTHH......C--HHHHHHHHHTT---S-SS----S............CHHTTEECCCCEEEETTTTEEE CS Trm112p 10 Cpackg......pLdwealvevaalglnelpkekpedy............ellleldieegeLvCpncgraY 63 C++c +L ++ v+v++++ +k+++e + +++ e e +Cp cg+ + tr|Q0VAI9|Q0VAI9_HUMAN 403 CHHCDAtfkrkdTL--NVHVQVVHER---HKKYRCELCnkafvtpsvlrsH--KKTHTGEKEKICPYCGQKF 467 56565555444455..6666777633...3444444445558899888662..5799999999*****9987 PP >> tr|H0Y3W3|H0Y3W3_HUMAN Exportin-5 (Fragment) OS=Homo sapiens GN=XPO5 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.0 0.0028 6.4 4 42 .. 11 63 .. 9 143 .. 0.90 2 ? 0.9 0.2 1.6 3.5e+03 6 25 .. 155 174 .. 151 186 .. 0.84 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.0028 GCCC-B-TTTHHC-..........-HHHHHHHHH.TT---S-SS----S....C CS Trm112p 4 llniLaCpackgpL..........dwealvevaa.lglnelpkekpedy....e 42 +++ L++p + gpL +w+++ +++ g +e ++e+pe + e tr|H0Y3W3|H0Y3W3_HUMAN 11 HYEALVSP-ILGPLftylhmrlsqKWQVINQRSLlCGEDEAADENPESQemleE 63 6789****.**************************************9844441 PP == domain 2 score: 0.9 bits; conditional E-value: 1.6 CC-B-TTTHHC--HHHHHHH CS Trm112p 6 niLaCpackgpLdwealvev 25 + L+C ++++L w+ l +v tr|H0Y3W3|H0Y3W3_HUMAN 155 DTLSCQRTTSQLCWPLLKQV 174 6799**99999999988876 PP >> sp|Q9Y2E6|DTX4_HUMAN E3 ubiquitin-protein ligase DTX4 OS=Homo sapiens GN=DTX4 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.2 0.00097 2.2 29 68 .] 421 476 .. 404 476 .. 0.74 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00097 T---.S-SS----S...............CHHTTEECCCCEEEETTTTEEEEEETT CS Trm112p 29 glne.lpkekpedy...............ellleldieegeLvCpncgraYpIkdG 68 g++ p kp+ + ++ ++ ++g+L+Cp c+ +Y +k G sp|Q9Y2E6|DTX4_HUMAN 421 GYKGpQPTVKPDLVgklsrcghvyhiyclVAMYNNGNKDGSLQCPTCKTIYGVKTG 476 555555666677667777777777777776677778889************99876 PP >> tr|D6RAL3|D6RAL3_HUMAN E3 ubiquitin-protein ligase SH3RF1 (Fragment) OS=Homo sapiens GN=SH3RF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 6.1 0.00059 1.3 3 61 .. 5 54 .. 3 55 .. 0.76 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00059 GGCCC-B-TTTHHC--HHHHHHHHHTT---.S-SS----S...CHHTTEECCCCEEEETTTTE CS Trm112p 3 lllniLaCpackgpLdwealvevaalglne.lpkekpedy...ellleldieegeLvCpncgr 61 ll++L Cp+c +L ++ lp + ll ++ ++eL Cp+c+ tr|D6RAL3|D6RAL3_HUMAN 5 ALLDLLECPVCLERL----------DASAKvLPCQH---TfckRCLLGIVGSRNELRCPECRT 54 69*************..........12223344444...2555999***************85 PP >> sp|Q9NQX1|PRDM5_HUMAN PR domain zinc finger protein 5 OS=Homo sapiens GN=PRDM5 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.2 0.00037 0.83 41 67 .. 175 212 .. 129 212 .. 0.79 2 ? -1.6 0.2 8.9 2e+04 47 60 .. 288 301 .. 253 303 .. 0.73 3 ? 4.6 0.1 0.11 2.4e+02 28 64 .. 368 414 .. 313 415 .. 0.66 4 ? 1.2 0.9 1.2 2.8e+03 10 63 .. 434 498 .. 430 499 .. 0.65 5 ? 1.7 0.4 0.88 2e+03 33 65 .. 542 584 .. 518 586 .. 0.62 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00037 S...........CHHTTEECCCCEEEETTTTEEEEEET CS Trm112p 41 y...........ellleldieegeLvCpncgraYpIkd 67 ++l++ ee e+ C+ncg +p+k+ sp|Q9NQX1|PRDM5_HUMAN 175 SftsedilaehlQTLHQKPTEEKEFKCKNCGKKFPVKQ 212 23333445555578889999****************85 PP == domain 2 score: -1.6 bits; conditional E-value: 8.9 EECCCCEEEETTTT CS Trm112p 47 ldieegeLvCpncg 60 + + + +L+C+ c+ sp|Q9NQX1|PRDM5_HUMAN 288 TGDPKKKLICSVCN 301 55556889999986 PP == domain 3 score: 4.6 bits; conditional E-value: 0.11 TT---S-SS----S............CHHTTEECCCCEEEETTTTEEEE CS Trm112p 28 lglnelpkekpedy............ellleldieegeLvCpncgraYp 64 + +e +++k++ + +++ ee ++C++c+ ++ sp|Q9NQX1|PRDM5_HUMAN 368 VIHSEDKPYKCKLCgkgfahrnvyknH--KKTHSEERPFQCEECKALFR 414 333445666666668888888888662..579************99885 PP == domain 4 score: 1.2 bits; conditional E-value: 1.2 -TTTHH......C--HHHHHHHHHTT---S-SS----S............CHHTTEECCCCEEEETTTTEEE CS Trm112p 10 Cpackg......pLdwealvevaalglnelpkekpedy............ellleldieegeLvCpncgraY 63 C++c +L ++ v+v++++ +k+++e + +++ e e +Cp cg+ + sp|Q9NQX1|PRDM5_HUMAN 434 CHHCDAtfkrkdTL--NVHVQVVHER---HKKYRCELCnkafvtpsvlrsH--KKTHTGEKEKICPYCGQKF 498 66666655455455..6667777633...3444444445558899888662..5799999999*****9987 PP == domain 5 score: 1.7 bits; conditional E-value: 0.88 S-SS----S............CHHTTEECCCCEEEETTTTEEEEE CS Trm112p 33 lpkekpedy............ellleldieegeLvCpncgraYpI 65 +++k+++ + +++ e ++C c++a+ sp|Q9NQX1|PRDM5_HUMAN 542 EKPYKCSECskafsqkrgldeH--KRTHTGEKPFQCDVCDLAFSL 584 4444554446777777777541..5689999999******99975 PP >> sp|Q9NQX1-2|PRDM5_HUMAN Isoform 2 of PR domain zinc finger protein 5 OS=Homo sapiens GN=PRDM5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 0.00037 0.84 41 67 .. 181 212 .. 152 212 .. 0.74 2 ? -1.7 0.2 9.7 2.2e+04 47 60 .. 257 270 .. 233 272 .. 0.72 3 ? 4.6 0.2 0.1 2.4e+02 28 64 .. 337 383 .. 282 384 .. 0.65 4 ? 1.3 0.9 1.1 2.6e+03 10 63 .. 403 467 .. 399 468 .. 0.65 5 ? 1.8 0.4 0.83 1.9e+03 33 65 .. 511 553 .. 487 555 .. 0.62 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00037 S.....CHHTTEECCCCEEEETTTTEEEEEET CS Trm112p 41 y.....ellleldieegeLvCpncgraYpIkd 67 + ++l++ ee e+ C+ncg +p+k+ sp|Q9NQX1-2|PRDM5_HUMAN 181 IlaehlQTLHQKPTEEKEFKCKNCGKKFPVKQ 212 144444778899999***************85 PP == domain 2 score: -1.7 bits; conditional E-value: 9.7 EECCCCEEEETTTT CS Trm112p 47 ldieegeLvCpncg 60 + + + +L+C+ c+ sp|Q9NQX1-2|PRDM5_HUMAN 257 TGDPKKKLICSVCN 270 55556899999997 PP == domain 3 score: 4.6 bits; conditional E-value: 0.1 TT---S-SS----S............CHHTTEECCCCEEEETTTTEEEE CS Trm112p 28 lglnelpkekpedy............ellleldieegeLvCpncgraYp 64 + +e +++k++ + +++ ee ++C++c+ ++ sp|Q9NQX1-2|PRDM5_HUMAN 337 VIHSEDKPYKCKLCgkgfahrnvyknH--KKTHSEERPFQCEECKALFR 383 333445666666668888888888662..579************99885 PP == domain 4 score: 1.3 bits; conditional E-value: 1.1 -TTTHH......C--HHHHHHHHHTT---S-SS----S............CHHTTEECCCCEEEETTTTEEE CS Trm112p 10 Cpackg......pLdwealvevaalglnelpkekpedy............ellleldieegeLvCpncgraY 63 C++c +L ++ v+v++++ +k+++e + +++ e e +Cp cg+ + sp|Q9NQX1-2|PRDM5_HUMAN 403 CHHCDAtfkrkdTL--NVHVQVVHER---HKKYRCELCnkafvtpsvlrsH--KKTHTGEKEKICPYCGQKF 467 66666655455555..6667777633...3444444445558899888662..5799999999*****9987 PP == domain 5 score: 1.8 bits; conditional E-value: 0.83 S-SS----S............CHHTTEECCCCEEEETTTTEEEEE CS Trm112p 33 lpkekpedy............ellleldieegeLvCpncgraYpI 65 +++k+++ + +++ e ++C c++a+ sp|Q9NQX1-2|PRDM5_HUMAN 511 EKPYKCSECskafsqkrgldeH--KRTHTGEKPFQCDVCDLAFSL 553 4444554446777777777541..5689999999******99975 PP >> tr|D6RHX5|D6RHX5_HUMAN E3 ubiquitin-protein ligase SH3RF1 (Fragment) OS=Homo sapiens GN=SH3RF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 5.5 0.0007 1.6 3 61 .. 5 54 .. 3 55 .. 0.76 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.0007 GGCCC-B-TTTHHC--HHHHHHHHHTT---.S-SS----S...CHHTTEECCCCEEEETTTTE CS Trm112p 3 lllniLaCpackgpLdwealvevaalglne.lpkekpedy...ellleldieegeLvCpncgr 61 ll++L Cp+c +L ++ lp + ll ++ ++eL Cp+c+ tr|D6RHX5|D6RHX5_HUMAN 5 ALLDLLECPVCLERL----------DASAKvLPCQH---TfckRCLLGIVGSRNELRCPECRT 54 69*************..........12223344444...2555999***************85 PP >> sp|O43623|SNAI2_HUMAN Zinc finger protein SNAI2 OS=Homo sapiens GN=SNAI2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.63 1.4e+03 42 63 .. 121 137 .. 73 142 .. 0.69 2 ? 6.5 0.5 0.027 61 43 63 .. 202 222 .. 144 223 .. 0.79 3 ? -0.4 0.0 3.8 8.7e+03 45 63 .. 232 250 .. 224 251 .. 0.79 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.63 CHHTTEECCCCEEEETTTTEEE CS Trm112p 42 ellleldieegeLvCpncgraY 63 + ie ++++C+ c+ +Y sp|O43623|SNAI2_HUMAN 121 H-----AIEAEKFQCNLCNKTY 137 3.....788899******9999 PP == domain 2 score: 6.5 bits; conditional E-value: 0.027 HHTTEECCCCEEEETTTTEEE CS Trm112p 43 llleldieegeLvCpncgraY 63 ++++ e + Cp+c+ra+ sp|O43623|SNAI2_HUMAN 202 GHIRTHTGEKPFSCPHCNRAF 222 44889999999*********9 PP == domain 3 score: -0.4 bits; conditional E-value: 3.8 TTEECCCCEEEETTTTEEE CS Trm112p 45 leldieegeLvCpncgraY 63 l+++ + + +C+nc ++ sp|O43623|SNAI2_HUMAN 232 LQTHSDVKKYQCKNCSKTF 250 77888888889****8877 PP >> tr|H7BXP3|H7BXP3_HUMAN Zinc finger protein 786 OS=Homo sapiens GN=ZNF786 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 1.4 0.073 1.7e+02 46 64 .. 387 405 .. 298 408 .. 0.83 2 ? 7.0 0.1 0.019 44 41 66 .. 489 519 .. 452 521 .. 0.71 3 ? 3.3 0.0 0.27 6e+02 50 66 .. 531 547 .. 522 549 .. 0.82 4 ? 2.5 0.0 0.48 1.1e+03 45 65 .. 581 601 .. 555 603 .. 0.82 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.073 TEECCCCEEEETTTTEEEE CS Trm112p 46 eldieegeLvCpncgraYp 64 +l+ +e ++Cp+cg+ ++ tr|H7BXP3|H7BXP3_HUMAN 387 RLHTDEKPFQCPECGLSFR 405 478899999*******997 PP == domain 2 score: 7.0 bits; conditional E-value: 0.019 S.....CHHTTEECCCCEEEETTTTEEEEEE CS Trm112p 41 y.....ellleldieegeLvCpncgraYpIk 66 ++ l+++ e ++Cp+c+r ++ k tr|H7BXP3|H7BXP3_HUMAN 489 TrqsklTEHLRVHSGERPFQCPECNRSFRLK 519 055555455889999999**********865 PP == domain 3 score: 3.3 bits; conditional E-value: 0.27 CCCEEEETTTTEEEEEE CS Trm112p 50 eegeLvCpncgraYpIk 66 e ++Cp+c+ Y++k tr|H7BXP3|H7BXP3_HUMAN 531 GERPFQCPECDKRYRVK 547 566789*********98 PP == domain 4 score: 2.5 bits; conditional E-value: 0.48 TTEECCCCEEEETTTTEEEEE CS Trm112p 45 leldieegeLvCpncgraYpI 65 ++++ e ++Cp+c+ ++ tr|H7BXP3|H7BXP3_HUMAN 581 IRTHTGEKPFQCPKCDKSFRL 601 678999999*******99985 PP >> tr|B4DMI1|B4DMI1_HUMAN Zinc finger protein 786 OS=Homo sapiens GN=ZNF786 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 1.5 0.087 2e+02 46 64 .. 436 454 .. 347 457 .. 0.83 2 ? 6.9 0.1 0.021 47 41 66 .. 538 568 .. 501 570 .. 0.71 3 ? 3.2 0.0 0.29 6.5e+02 50 66 .. 580 596 .. 571 598 .. 0.82 4 ? 2.4 0.0 0.52 1.2e+03 45 65 .. 630 650 .. 604 652 .. 0.82 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.087 TEECCCCEEEETTTTEEEE CS Trm112p 46 eldieegeLvCpncgraYp 64 +l+ +e ++Cp+cg+ ++ tr|B4DMI1|B4DMI1_HUMAN 436 RLHTDEKPFQCPECGLSFR 454 478899999*******997 PP == domain 2 score: 6.9 bits; conditional E-value: 0.021 S.....CHHTTEECCCCEEEETTTTEEEEEE CS Trm112p 41 y.....ellleldieegeLvCpncgraYpIk 66 ++ l+++ e ++Cp+c+r ++ k tr|B4DMI1|B4DMI1_HUMAN 538 TrqsklTEHLRVHSGERPFQCPECNRSFRLK 568 055555455889999999**********865 PP == domain 3 score: 3.2 bits; conditional E-value: 0.29 CCCEEEETTTTEEEEEE CS Trm112p 50 eegeLvCpncgraYpIk 66 e ++Cp+c+ Y++k tr|B4DMI1|B4DMI1_HUMAN 580 GERPFQCPECDKRYRVK 596 566789*********98 PP == domain 4 score: 2.4 bits; conditional E-value: 0.52 TTEECCCCEEEETTTTEEEEE CS Trm112p 45 leldieegeLvCpncgraYpI 65 ++++ e ++Cp+c+ ++ tr|B4DMI1|B4DMI1_HUMAN 630 IRTHTGEKPFQCPKCDKSFRL 650 678999999*******99985 PP >> tr|A2AE48|A2AE48_HUMAN Tripartite motif-containing protein 26 (Fragment) OS=Homo sapiens GN=TRIM26 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 1.4 0.0017 3.8 9 60 .. 52 125 .. 52 127 .. 0.77 2 ? -0.7 0.0 4.9 1.1e+04 41 54 .. 189 217 .. 153 221 .. 0.71 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.0017 B-TTTHHC-.........-HHHHHHHHH.TT---.S-SS----S...........CHHTTEECCCCEEEETTTT CS Trm112p 9 aCpackgpL.........dwealvevaa.lglne.lpkekpedy...........ellleldieegeLvCpncg 60 +Cp+ck+p ++++lve+ + l+ ++ ++ ++ e l+ +++++g+L C c+ tr|A2AE48|A2AE48_HUMAN 52 VCPLCKKPFkkenirpvwQLASLVENIErLKVDKgRQPGEVTREqqdaklcerhrEKLHYYCEDDGKLLCVMCR 125 7******66666666767667777777777777766666666668999999999988999**********9987 PP == domain 2 score: -0.7 bits; conditional E-value: 4.9 S...............CHHTTEECCCCEE CS Trm112p 41 y...............ellleldieegeL 54 + +ll +l ++e+eL tr|A2AE48|A2AE48_HUMAN 189 VaefeqghqflrereeHLLEQLAKLEQEL 217 14444444555666668888888888888 PP >> sp|Q8N393|ZN786_HUMAN Zinc finger protein 786 OS=Homo sapiens GN=ZNF786 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 1.3 0.083 1.9e+02 46 64 .. 473 491 .. 384 494 .. 0.84 2 ? 6.8 0.1 0.022 51 41 66 .. 575 605 .. 538 607 .. 0.71 3 ? 3.1 0.0 0.3 6.9e+02 50 66 .. 617 633 .. 608 635 .. 0.82 4 ? 2.3 0.0 0.55 1.2e+03 45 65 .. 667 687 .. 640 689 .. 0.82 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.083 TEECCCCEEEETTTTEEEE CS Trm112p 46 eldieegeLvCpncgraYp 64 +l+ +e ++Cp+cg+ ++ sp|Q8N393|ZN786_HUMAN 473 RLHTDEKPFQCPECGLSFR 491 478899999*******997 PP == domain 2 score: 6.8 bits; conditional E-value: 0.022 S.....CHHTTEECCCCEEEETTTTEEEEEE CS Trm112p 41 y.....ellleldieegeLvCpncgraYpIk 66 ++ l+++ e ++Cp+c+r ++ k sp|Q8N393|ZN786_HUMAN 575 TrqsklTEHLRVHSGERPFQCPECNRSFRLK 605 055555455889999999**********865 PP == domain 3 score: 3.1 bits; conditional E-value: 0.3 CCCEEEETTTTEEEEEE CS Trm112p 50 eegeLvCpncgraYpIk 66 e ++Cp+c+ Y++k sp|Q8N393|ZN786_HUMAN 617 GERPFQCPECDKRYRVK 633 566789*********98 PP == domain 4 score: 2.3 bits; conditional E-value: 0.55 TTEECCCCEEEETTTTEEEEE CS Trm112p 45 leldieegeLvCpncgraYpI 65 ++++ e ++Cp+c+ ++ sp|Q8N393|ZN786_HUMAN 667 IRTHTGEKPFQCPKCDKSFRL 687 678999999*******99985 PP >> sp|Q8NEM1|ZN680_HUMAN Zinc finger protein 680 OS=Homo sapiens GN=ZNF680 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 1.2 0.0048 11 10 63 .. 212 275 .. 169 277 .. 0.82 2 ? -0.1 5.2 3.1 7.1e+03 28 63 .. 341 387 .. 293 508 .. 0.73 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0048 -TTTHHC--HHHHHHHHH.TT---.S-SS----S............CHHTTEECCCCEEEETTTTEEE CS Trm112p 10 CpackgpLdwealvevaa.lglne.lpkekpedy............ellleldieegeLvCpncgraY 63 C c + L + ++e + +g+ + +++k+e+ + +++iee + C++cg a+ sp|Q8NEM1|ZN680_HUMAN 212 CEECGKVL--NWFSELIKhKGIHMgEKPYKCEECgkafnqsstlikH--KKIHIEEKPFKCEECGKAF 275 55555555..4444445556788888899999989999999888773..469**************99 PP == domain 2 score: -0.1 bits; conditional E-value: 3.1 TT---.S-SS----S............CHHTTEECCCCEEEETTTTEEE CS Trm112p 28 lglne.lpkekpedy............ellleldieegeLvCpncgraY 63 +++ + +++k+e+ + +++ e + C++cg a+ sp|Q8NEM1|ZN680_HUMAN 341 KKIHTgEKPYKCEECgkafnqfanltrH--KKIHTGEKSYKCEECGKAF 387 4444445555555556666666666441..3455555666666666555 PP >> tr|F5H1B4|F5H1B4_HUMAN Zinc finger protein 562 OS=Homo sapiens GN=ZNF562 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 8.1 1.8e+04 56 63 .. 11 18 .. 10 19 .. 0.90 2 ? 10.6 0.0 0.0015 3.3 41 64 .. 149 182 .. 89 182 .. 0.78 3 ? -0.4 1.9 4 9.1e+03 56 63 .. 230 237 .. 201 266 .. 0.54 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 8.1 ETTTTEEE CS Trm112p 56 CpncgraY 63 C+ncg ++ tr|F5H1B4|F5H1B4_HUMAN 11 CENCGEVF 18 *****998 PP == domain 2 score: 10.6 bits; conditional E-value: 0.0015 S..........CHHTTEECCCCEEEETTTTEEEE CS Trm112p 41 y..........ellleldieegeLvCpncgraYp 64 ++ ++++ e ++ C++cgr ++ tr|F5H1B4|F5H1B4_HUMAN 149 CgksftnfsqlSAHAKTHKGEKSFECKECGRSFR 182 1555666667755678***************996 PP == domain 3 score: -0.4 bits; conditional E-value: 4 ETTTTEEE CS Trm112p 56 CpncgraY 63 C++cg+a+ tr|F5H1B4|F5H1B4_HUMAN 230 CKECGQAF 237 33333333 PP >> sp|Q9HBF4-2|ZFYV1_HUMAN Isoform 2 of Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens GN=ZFYVE1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.1 0.17 3.9e+02 53 64 .. 93 104 .. 56 106 .. 0.84 2 ? -1.3 0.0 7.3 1.7e+04 52 61 .. 185 194 .. 176 200 .. 0.70 3 ? 4.2 1.3 0.14 3.2e+02 42 66 .. 296 316 .. 184 318 .. 0.78 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.17 EEEETTTTEEEE CS Trm112p 53 eLvCpncgraYp 64 ++ Cpncg +Y+ sp|Q9HBF4-2|ZFYV1_HUMAN 93 VIECPNCGVVYR 104 678********6 PP == domain 2 score: -1.3 bits; conditional E-value: 7.3 CEEEETTTTE CS Trm112p 52 geLvCpncgr 61 + L C++c sp|Q9HBF4-2|ZFYV1_HUMAN 185 QILSCNKCAT 194 4466666655 PP == domain 3 score: 4.2 bits; conditional E-value: 0.14 CHHTTEECCCCEEEETTTTEEEEEE CS Trm112p 42 ellleldieegeLvCpncgraYpIk 66 + ++ +++ L C+nc+ + Ik sp|Q9HBF4-2|ZFYV1_HUMAN 296 Y----WVPDHEILHCHNCRKEFSIK 316 4....67788889999999999997 PP >> tr|J3QQL1|J3QQL1_HUMAN Zinc finger protein 236 (Fragment) OS=Homo sapiens GN=ZNF236 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.8 0.015 34 10 63 .. 95 130 .. 63 133 .. 0.76 2 ? 3.6 0.4 0.22 5.1e+02 41 63 .. 176 234 .. 154 235 .. 0.52 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.015 -TTTHHC--HHHHHHHHHTT---S-SS----S.......CHHTTEECCCCEEEETTTTEEE CS Trm112p 10 CpackgpLdwealvevaalglnelpkekpedy.......ellleldieegeLvCpncgraY 63 Cp+c + ++ + l+++e+ L+C++cg + tr|J3QQL1|J3QQL1_HUMAN 95 CPVCNK-------------------------KfsrvaslKAHIMLHEKEENLICSECGDEF 130 444444.........................03333444556889************9766 PP == domain 2 score: 3.6 bits; conditional E-value: 0.22 S....................................CHHTTEECCCCEEEETTTTEEE CS Trm112p 41 y....................................ellleldieegeLvCpncgraY 63 y + ++++ e + C++cg a+ tr|J3QQL1|J3QQL1_HUMAN 176 YkirvsstrsynrnidrsgftyscphcgktfqkpsqlTRHIRIHTGERPFKCSECGKAF 234 44444444444444444444444444444455555444447788888888888888887 PP >> tr|B4DNX9|B4DNX9_HUMAN Zinc finger protein 460 OS=Homo sapiens GN=ZNF460 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.4 0.22 4.9e+02 46 63 .. 203 220 .. 146 221 .. 0.75 2 ? 2.5 0.1 0.49 1.1e+03 47 63 .. 232 248 .. 225 251 .. 0.84 3 ? 1.0 0.5 1.4 3.2e+03 47 63 .. 316 332 .. 256 333 .. 0.79 4 ? 5.1 0.0 0.076 1.7e+02 51 67 .. 348 364 .. 334 365 .. 0.83 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.22 TEECCCCEEEETTTTEEE CS Trm112p 46 eldieegeLvCpncgraY 63 +++ + +vC++cgr++ tr|B4DNX9|B4DNX9_HUMAN 203 RTHNGDKPFVCSECGRTF 220 467777889*******98 PP == domain 2 score: 2.5 bits; conditional E-value: 0.49 EECCCCEEEETTTTEEE CS Trm112p 47 ldieegeLvCpncgraY 63 ++ e +vC++cg a+ tr|B4DNX9|B4DNX9_HUMAN 232 VHSGEKPFVCNECGKAF 248 56678889******999 PP == domain 3 score: 1.0 bits; conditional E-value: 1.4 EECCCCEEEETTTTEEE CS Trm112p 47 ldieegeLvCpncgraY 63 ++ e +vC+ cg a+ tr|B4DNX9|B4DNX9_HUMAN 316 IHTGEKPFVCSQCGKAF 332 55667778999999887 PP == domain 4 score: 5.1 bits; conditional E-value: 0.076 CCEEEETTTTEEEEEET CS Trm112p 51 egeLvCpncgraYpIkd 67 e + C++cg a+ I++ tr|B4DNX9|B4DNX9_HUMAN 348 EKPFECKECGKAFSIRK 364 66789**********96 PP >> sp|O75437-2|ZN254_HUMAN Isoform 2 of Zinc finger protein 254 OS=Homo sapiens GN=ZNF254 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 1.3 0.0009 2 9 63 .. 211 275 .. 176 276 .. 0.87 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.0009 B-TTTHHC--HHHHHHHHHTT---S-SS----S.......CHHTTEECCC..CEEE.ETTTTEEE CS Trm112p 9 aCpackgpLdwealvevaalglnelpkekpedy.......ellleldiee..geLv.CpncgraY 63 +C c ++ w++ +++ ++ ++e +++k+e+y ++l ++i++ ++L+ C++cg a+ sp|O75437-2|ZN254_HUMAN 211 KCKECGKTFNWSSTLTNHRKIYTEEKPYKCEEYnkspkqlSTLTTHEIIHagEKLYkCEECGEAF 275 688888889999999999988888****************44555555555588877*****999 PP >> sp|Q9C026-5|TRIM9_HUMAN Isoform 5 of E3 ubiquitin-protein ligase TRIM9 OS=Homo sapiens GN=TRIM9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.2 0.044 1e+02 48 64 .. 2 18 .. 1 18 [. 0.88 2 ? 2.1 4.6 0.65 1.5e+03 8 60 .. 126 245 .. 124 247 .. 0.65 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.044 ECCCCEEEETTTTEEEE CS Trm112p 48 dieegeLvCpncgraYp 64 +++e+eL Cp cg Y+ sp|Q9C026-5|TRIM9_HUMAN 2 EEMEEELKCPVCGSFYR 18 689**********9885 PP == domain 2 score: 2.1 bits; conditional E-value: 0.65 -B-TTTHHC-..............-HHHHHHHHH.TT---S-SS----S..................................... CS Trm112p 8 LaCpackgpL..............dwealvevaa.lglnelpkekpedy..................................... 41 ++Cp+c+ L +e ++++ + + + l+ +++e++ sp|Q9C026-5|TRIM9_HUMAN 126 ITCPQCHRSLilddrglrgfpknrVLEGVIDRYQqSKAAALKCQLCEKApkeatvmceqcdvfycdpcrlrchpprgplakhrlvp 211 57888888777777777777777767777777777777777777777778666655555555555555555555555555556666 PP ...............CHHTTEECCCCEEEETTTT CS Trm112p 42 ...............ellleldieegeLvCpncg 60 +++ ++ e+ +++C c+ sp|Q9C026-5|TRIM9_HUMAN 212 paqgrvsrrlsprkvSTCTDHELENHSMYCVQCK 245 6666666666666666666677777777777765 PP >> sp|Q7Z6J0-3|SH3R1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase SH3RF1 OS=Homo sapiens GN=SH3RF1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 5.5 0.011 25 3 60 .. 5 53 .. 3 55 .. 0.76 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.011 GGCCC-B-TTTHHC--HHHHHHHHHTT---.S-SS----S...CHHTTEECCCCEEEETTTT CS Trm112p 3 lllniLaCpackgpLdwealvevaalglne.lpkekpedy...ellleldieegeLvCpncg 60 ll++L Cp+c +L ++ lp + ll ++ ++eL Cp+c+ sp|Q7Z6J0-3|SH3R1_HUMAN 5 ALLDLLECPVCLERL----------DASAKvLPCQH---TfckRCLLGIVGSRNELRCPECR 53 69*************..........12223344444...25559999**************8 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (68 nodes) Target sequences: 88473 (35070517 residues searched) Passed MSV filter: 4282 (0.0483989); expected 1769.5 (0.02) Passed bias filter: 3172 (0.0358527); expected 1769.5 (0.02) Passed Vit filter: 349 (0.00394471); expected 88.5 (0.001) Passed Fwd filter: 117 (0.00132244); expected 0.9 (1e-05) Initial search space (Z): 88473 [actual number of targets] Domain search space (domZ): 39 [number of targets reported over threshold] # CPU time: 0.87u 0.02s 00:00:00.89 Elapsed: 00:00:00.30 # Mc/sec: 7949.32 // [ok]