# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Trm112p.hmm.txt
# target sequence database:        proteomes/Petromyzon_marinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Trm112p  [M=68]
Accession:   PF03966.15
Description: Trm112p-like protein
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.9e-13   50.4   0.0    2.4e-13   50.0   0.0    1.2  1  tr|S4RJ54|S4RJ54_PETMA  tRNA methyltransferase 11-2 homolog (
  ------ inclusion threshold ------
       0.02   15.0   0.5        3.9    7.7   0.1    2.1  2  tr|S4RBH8|S4RBH8_PETMA  Uncharacterized protein OS=Petromyzon
      0.032   14.4   7.9        1.1    9.5   0.3    2.7  2  tr|S4RAA1|S4RAA1_PETMA  Uncharacterized protein OS=Petromyzon
      0.039   14.1  12.4       0.26   11.5   0.1    4.8  3  tr|S4RKN7|S4RKN7_PETMA  PR domain containing 5 OS=Petromyzon 
      0.044   14.0   2.1       0.69   10.1   0.1    2.7  3  tr|S4RZQ5|S4RZQ5_PETMA  Uncharacterized protein OS=Petromyzon
       0.11   12.7  14.8    1.4e+04   -3.8  14.8    5.3  1  tr|S4RSZ2|S4RSZ2_PETMA  Uncharacterized protein OS=Petromyzon
       0.29   11.3   3.0       0.74   10.0   0.6    2.7  2  tr|S4RGW7|S4RGW7_PETMA  Tripartite motif containing 59 OS=Pet
        1.6    8.9  14.3         12    6.2   2.2    5.2  3  tr|S4R5M4|S4R5M4_PETMA  Zinc finger protein 22 OS=Petromyzon 
        2.1    8.6  10.5          2    8.7   0.1    4.3  4  tr|S4RG83|S4RG83_PETMA  Uncharacterized protein OS=Petromyzon
        2.5    8.3  15.0         30    4.9   6.7    4.0  3  tr|S4RDD1|S4RDD1_PETMA  Uncharacterized protein OS=Petromyzon


Domain annotation for each sequence (and alignments):
>> tr|S4RJ54|S4RJ54_PETMA  tRNA methyltransferase 11-2 homolog (S. cerevisiae) OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.0   0.0   1.8e-16   2.4e-13       1      68 []       2     112 ..       2     112 .. 0.95

  Alignments for each domain:
  == domain 1  score: 50.0 bits;  conditional E-value: 1.8e-16
                             BTGGCCC-B-TTTHH.....C-..........................-HHHHHHHHH.TT---.S-SS----S...........CH CS
                 Trm112p   1 kllllniLaCpackg.....pL..........................dwealvevaa.lglne.lpkekpedy...........el 43 
                             kll++n+L+++ +kg     pL                          +w+al ++a+  g    lp e   +y           ++
  tr|S4RJ54|S4RJ54_PETMA   2 KLLTHNMLTSH-VKGvtkgfPLkitatevkvmnvdfnpefvarmipklEWPALCQAAEsIGHLNnLPLEVDPNYqgnedflkkvhHV 87 
                             789********.********99************************************97766669999988889************ PP

                             HTTEECCCCEEEETTTTEEEEEETT CS
                 Trm112p  44 lleldieegeLvCpncgraYpIkdG 68 
                             l+e++++eg+L+Cp+ gr +pI +G
  tr|S4RJ54|S4RJ54_PETMA  88 LMEVEVVEGSLQCPESGRQFPITKG 112
                             **********************987 PP

>> tr|S4RBH8|S4RBH8_PETMA  Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.1    0.0029       3.9      26      63 ..      10      55 ..       4      56 .. 0.70
   2 ?    5.9   0.1      0.01        14       6      17 ..      66      77 ..      61      85 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0029
                            HH.TT---S-SS----S.......CHHTTEECCCCEEEETTTTEEE CS
                 Trm112p 26 aa.lglnelpkekpedy.......ellleldieegeLvCpncgraY 63
                            aa ++ +e p+  pe+        ++l ++++    + ++ cg+++
  tr|S4RBH8|S4RBH8_PETMA 10 AAgAQGAEKPASEPETTiscplclDELNQVHMSGRLMCSTVCGHVF 55
                            4445555666666666678889997788888877777778899998 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.01
                            CC-B-TTTHHC- CS
                 Trm112p  6 niLaCpackgpL 17
                            ++ +Cp+c+++L
  tr|S4RBH8|S4RBH8_PETMA 66 SMAKCPFCRKKL 77
                            5789******99 PP

>> tr|S4RAA1|S4RAA1_PETMA  Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.3   0.00083       1.1      39      64 ..      18      39 ..       1      42 [. 0.65
   2 ?    7.5   2.4    0.0035       4.7       7      61 ..      56     122 ..      53     123 .. 0.63

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00083
                            --SCHHTTEECCCCEEEETTTTEEEE CS
                 Trm112p 39 edyellleldieegeLvCpncgraYp 64
                            e+      +++++++L C+ c+r + 
  tr|S4RAA1|S4RAA1_PETMA 18 EH----ATMHVDRETLECRVCRRKFS 39
                            22....348999***********995 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0035
                             C-B-TTTHHC-........-HHHHHHHHHTT---S-SS----S.................CHHTTEECCCCEEEETTTTE CS
                 Trm112p   7 iLaCpackgpL........dwealvevaalglnelpkekpedy.................ellleldieegeLvCpncgr 61 
                             +L+C+ c ++L                    ++  ++ k+  +                 +   +l+++ ++LvC+ cg+
  tr|S4RAA1|S4RAA1_PETMA  56 VLSCNDCGKKLlsparlslH-----------YKNCKMRKSYAAcqvcgmavpkkmavvrrH--ARLHVDMEKLVCKVCGL 122
                             79999999988333333331...........333333333333556666666666777653..5699999********96 PP

>> tr|S4RKN7|S4RKN7_PETMA  PR domain containing 5 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   0.00019      0.26      36      67 ..      15      46 ..       2      46 .. 0.74
   2 ?    5.3   0.5     0.017        23       5      63 ..     152     248 ..     112     250 .. 0.71
   3 ?    1.0   1.9      0.38   5.1e+02      10      63 ..     291     354 ..     254     359 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00019
                            S----SCHHTTEECCCCEEEETTTTEEEEEET CS
                 Trm112p 36 ekpedyellleldieegeLvCpncgraYpIkd 67
                             + e++++l++   ee  + C++cg  +p+k+
  tr|S4RKN7|S4RKN7_PETMA 15 VLAEHVQTLHQRGPEEKDFRCRSCGKRFPVKQ 46
                            3455668999********************85 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.017
                             CCC-B-TTTHH......C-....................-HHHHHHHHH.TT---.S-SS----S............CHHTTEECCC CS
                 Trm112p   5 lniLaCpackg......pL....................dwealvevaa.lglne.lpkekpedy............ellleldiee 51 
                             ++i  C  c +      +L                     ++ l +va  + + +  ++++++              +   +++ ee
  tr|S4RKN7|S4RKN7_PETMA 152 HEIFDCQDCDKkfisanQLrrhmithsekrpfscevcgkSFKRLDQVAShKVIHSvDKPYTCKLCgkgfahrnvyknH--KKTHSEE 236
                             555555555553443333345555555555555555555445555666666666666677777668888888888662..57999** PP

                             CEEEETTTTEEE CS
                 Trm112p  52 geLvCpncgraY 63 
                               ++C++c+  +
  tr|S4RKN7|S4RKN7_PETMA 237 RPFQCEECKALF 248
                             ********9888 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.38
                             -TTTHH......C--HHHHHHHHH.TT---S-SS----S..........CHHTTEECCCCEEEETTTTEEE CS
                 Trm112p  10 Cpackg......pLdwealvevaa.lglnelpkekpedy..........ellleldieegeLvCpncgraY 63 
                             Cp+c +      +L       +++ +  +  ++++++            +  ++++  e   +C++c+ a+
  tr|S4RKN7|S4RKN7_PETMA 291 CPYCGQkfasngTL-------RVHiRSHTGERPYQCQYCdkafskndglKMHIRTHTREKPYQCSECNKAF 354
                             55555533333333.......22222222233333332245566666663336666666666777777666 PP

>> tr|S4RZQ5|S4RZQ5_PETMA  Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.1      0.14   1.9e+02      51      63 ..      10      22 ..       7      23 .. 0.88
   2 ?    2.2   0.2      0.16   2.1e+02      55      64 ..      49      58 ..      36      59 .. 0.80
   3 ?   10.1   0.1   0.00051      0.69       9      59 ..      49     120 ..      48     123 .. 0.80

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.14
                            CCEEEETTTTEEE CS
                 Trm112p 51 egeLvCpncgraY 63
                            e+eL+C+ c + Y
  tr|S4RZQ5|S4RZQ5_PETMA 10 EEELTCSICLHLY 22
                            89*******9998 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.16
                            EETTTTEEEE CS
                 Trm112p 55 vCpncgraYp 64
                             Cp+c+r+ p
  tr|S4RZQ5|S4RZQ5_PETMA 49 ACPECRRVLP 58
                            6999999865 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00051
                             B-TTTHH............C--HHHHHHHHH.TT---S-SS----S................CHHTTEECCCCEEEETTT CS
                 Trm112p   9 aCpackg............pLdwealvevaa.lglnelpkekpedy................ellleldieegeLvCpnc 59 
                             aCp c+             +L        ++ ++l+++ +  +++                 ++l  +++e+g++vC++c
  tr|S4RZQ5|S4RZQ5_PETMA  49 ACPECRRvlpfgskeemrkQL--------EKnFKLASIVDRFCSREkiphrgtpvfqcgqhgKALAMFCREHGAFVCTDC 120
                             799999966555555544444........6667788888888888899999999999*****99**************99 PP

>> tr|S4RSZ2|S4RSZ2_PETMA  Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8  14.8        10   1.4e+04      41      66 ..      52      89 ..       1     145 [. 0.76

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 10
                            S............CHHTTEECCCCEEEETTTTEEEEEE CS
                 Trm112p 41 y............ellleldieegeLvCpncgraYpIk 66
                            +            e+ + ++ ee++L++++ +  Y I+
  tr|S4RSZ2|S4RSZ2_PETMA 52 VlynneehvlynnEEQVLYNNEEQVLYNNEEHVLYNIE 89
                            13444333455554445567777777777777777776 PP

>> tr|S4RGW7|S4RGW7_PETMA  Tripartite motif containing 59 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.1       1.1   1.4e+03      50      59 ..       4      13 ..       1      18 [. 0.72
   2 ?   10.0   0.6   0.00055      0.74       8      59 ..      55     131 ..      54     134 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 1.1
                            CCCEEEETTT CS
                 Trm112p 50 eegeLvCpnc 59
                            +e+ L+Cp c
  tr|S4RGW7|S4RGW7_PETMA  4 LEEDLTCPVC 13
                            5777888877 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00055
                             -B-TTTHH............C--HHHHHHHHH.TT---S-SS----S............CHHTTEECCCCEEEETTT CS
                 Trm112p   8 LaCpackg............pLdwealvevaa.lglnelpkekpedy............ellleldieegeLvCpnc 59 
                             L+Cp c++            pL ++ +  v++ +++++l++e+                + l  ++ ++ +LvC  c
  tr|S4RGW7|S4RGW7_PETMA  55 LKCPSCRHmfdmpsaglsylPLNYSLVAIVEKyRRQQKLQRERELAEsarppacaehseQPLNVYCLTDRTLVCGFC 131
                             89******************999999999999888888776665444578888888888445558888899999877 PP

>> tr|S4R5M4|S4R5M4_PETMA  Zinc finger protein 22 OS=Petromyzon marinus OX=7757 GN=ZNF22 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   2.2    0.0088        12      45      63 ..      78      96 ..       2      99 .. 0.75
   2 ?    3.1   0.2     0.083   1.1e+02      38      63 ..     117     152 ..      97     153 .. 0.62
   3 ?   -1.1   0.6       1.6   2.2e+03      63      63 ..     181     181 ..     162     210 .. 0.55

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0088
                            TTEECCCCEEEETTTTEEE CS
                 Trm112p 45 leldieegeLvCpncgraY 63
                             +++ +e +L+C +cg  +
  tr|S4R5M4|S4R5M4_PETMA 78 QNTHTTEKSLTCDKCGKSF 96
                            3488889999999998877 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.083
                             ---S............CHHTTEECCCCEEEETTTTEEE CS
                 Trm112p  38 pedy............ellleldieegeLvCpncgraY 63 
                             +e+             +   +++ ++g+ vC +cg  +
  tr|S4R5M4|S4R5M4_PETMA 117 CEQCgkkfmmisylkiH--QKTHTLDGKHVCDECGKKF 152
                             33336666666666442..5688888999999999776 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 1.6
                             E CS
                 Trm112p  63 Y 63 
                             +
  tr|S4R5M4|S4R5M4_PETMA 181 F 181
                             3 PP

>> tr|S4RG83|S4RG83_PETMA  Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1       1.1   1.5e+03      53      63 ..      63      73 ..      25      74 .. 0.73
   2 ?    3.7   0.1     0.053        71      45      66 ..     146     167 ..      93     169 .. 0.72
   3 ?   -1.4   0.2       2.1   2.9e+03      56      63 ..     185     192 ..     176     193 .. 0.85
   4 ?    8.7   0.1    0.0014         2      38      63 ..     226     250 ..     210     251 .. 0.71

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 1.1
                            EEEETTTTEEE CS
                 Trm112p 53 eLvCpncgraY 63
                            +  C  cgra+
  tr|S4RG83|S4RG83_PETMA 63 KHECGVCGRAF 73
                            44688888888 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.053
                             TTEECCCCEEEETTTTEEEEEE CS
                 Trm112p  45 leldieegeLvCpncgraYpIk 66 
                             +  +  e  + C  cgr++ +k
  tr|S4RG83|S4RG83_PETMA 146 ISAHASEKPFACDVCGRTFAVK 167
                             5567778888999999999987 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 2.1
                             ETTTTEEE CS
                 Trm112p  56 CpncgraY 63 
                             C +c+r+Y
  tr|S4RG83|S4RG83_PETMA 185 CAECDRVY 192
                             9******9 PP

  == domain 4  score: 8.7 bits;  conditional E-value: 0.0014
                             ---S....CHHTTEECCCCEEEETTTTEEE CS
                 Trm112p  38 pedy....ellleldieegeLvCpncgraY 63 
                             ++++    e     + +e ++ Cp+cgra+
  tr|S4RG83|S4RG83_PETMA 226 SQRPqlegE-----ETTEKVIECPECGRAF 250
                             444422243.....67889**********9 PP

>> tr|S4RDD1|S4RDD1_PETMA  Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   6.7     0.022        30       7      63 ..       2      95 ..       1      96 [. 0.65
   2 ?    3.1   0.1     0.081   1.1e+02      47      63 ..     106     122 ..      97     123 .. 0.81
   3 ?    3.0   0.1     0.085   1.2e+02      47      63 ..     133     149 ..     124     150 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.022
                            C-B-TTTHHC-...........................-HHHHHHHHH..TT---S-SS----S...........CHHTTEECCCCEEE CS
                 Trm112p  7 iLaCpackgpL...........................dwealvevaa..lglnelpkekpedy...........ellleldieegeLv 55
                            +L+Cp+ck  L                            ++   +++   lg ++ + +++e+            e   ++++e+  L 
  tr|S4RDD1|S4RDD1_PETMA  2 LLQCPLCKWVLishaalqdhmkqhgrqigveyfqcgwcSYSTYCRRTLthLGKKDYKCKRCERSytrlgalhthhE---RTHEEQKPLL 87
                            7999999997766666677777777777777777766644433333321344444455555555999999976542...58888899** PP

                            ETTTTEEE CS
                 Trm112p 56 CpncgraY 63
                            C++cg a+
  tr|S4RDD1|S4RDD1_PETMA 88 CSECGEAF 95
                            ******99 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.081
                             EECCCCEEEETTTTEEE CS
                 Trm112p  47 ldieegeLvCpncgraY 63 
                              + e+  L C++cg a+
  tr|S4RDD1|S4RDD1_PETMA 106 RSHEQKPLLCSECGEAF 122
                             55677889*******99 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.085
                             EECCCCEEEETTTTEEE CS
                 Trm112p  47 ldieegeLvCpncgraY 63 
                              + e+  L C++cg a+
  tr|S4RDD1|S4RDD1_PETMA 133 RSHEQKPLLCSECGEAF 149
                             55677889*******99 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (68 nodes)
Target sequences:                        13539  (5048892 residues searched)
Passed MSV filter:                       536  (0.0395893); expected 270.8 (0.02)
Passed bias filter:                      418  (0.0308738); expected 270.8 (0.02)
Passed Vit filter:                        54  (0.00398848); expected 13.5 (0.001)
Passed Fwd filter:                        20  (0.00147721); expected 0.1 (1e-05)
Initial search space (Z):              13539  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.14u 0.00s 00:00:00.14 Elapsed: 00:00:00.05
# Mc/sec: 6866.49
//
[ok]