# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TruB_N.hmm.txt # target sequence database: proteomes/Ciona_savignyi.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TruB_N [M=149] Accession: PF01509.17 Description: TruB family pseudouridylate synthase (N terminal domain) Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-23 82.1 4.0 3.3e-21 75.6 0.1 3.6 2 tr|H2ZHM3|H2ZHM3_CIOSA Uncharacterized protein OS=Ciona savi 4.2e-11 42.8 0.0 7.1e-11 42.1 0.0 1.2 1 tr|H2YML1|H2YML1_CIOSA Uncharacterized protein OS=Ciona savi Domain annotation for each sequence (and alignments): >> tr|H2ZHM3|H2ZHM3_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 75.6 0.1 5.7e-25 3.3e-21 1 149 [] 100 216 .. 100 216 .. 0.94 2 ? -3.0 0.7 0.94 5.4e+03 62 77 .. 469 479 .. 449 497 .. 0.45 Alignments for each domain: == domain 1 score: 75.6 bits; conditional E-value: 5.7e-25 HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EE CS TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGe 87 +r+lk++k Gh+GtLDp++tG+L+v+v++aT+l+++ ++a KeY++ +rl+ + ++e kl ++++++tG+ tr|H2ZHM3|H2ZHM3_CIOSA 100 RRILKVEKTGHSGTLDPKVTGCLIVCVERATRLVKSQQSAGKEYVCIVRLHSAIENE-----------------LKLARAIETLTGA 169 89************************************************9987654.................368999******* PP E---------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS TruB_N 88 ieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149 + q+pp +SAvk r+ r tiy+ +lle++e+ + v+c++GtYi tr|H2ZHM3|H2ZHM3_CIOSA 170 LFQRPPLISAVK-----------------RQLRVRTIYQSKLLEFDEEkrLGVFWVSCEAGTYI 216 ************.................999*************988767899*********8 PP == domain 2 score: -3.0 bits; conditional E-value: 0.94 -EEE-.--TT--HHHH CS TruB_N 62 eileeekveklteekl 77 + ek +++++ tr|H2ZHM3|H2ZHM3_CIOSA 469 KKE-----EKAKKKEV 479 111.....11111111 PP >> tr|H2YML1|H2YML1_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.1 0.0 1.2e-14 7.1e-11 13 145 .. 102 237 .. 97 241 .. 0.89 Alignments for each domain: == domain 1 score: 42.1 bits; conditional E-value: 1.2e-14 S---TT-EEEEEEEEGGG....GGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE------- CS TruB_N 13 GtLDplatGvLvvavgea....TklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeieqvppmy 95 LD a Gv v++v+++ Tk +++ +++Y++ ++g ++ t+ + +ile+++++++t +k+++vl++++ + + tr|H2YML1|H2YML1_CIOSA 102 NLLDADACGVQVIGVDKKgenlTKRYQNM-GLPRKYKVHGQFGFASMTHSPKSRILERSTWDHVTADKISRVLTTIQVSHRNAMLRD 187 569************98521114444443.4569************************99*************************** PP --------------------------EEEEEEEEEEEEEEEEEEEEEEST CS TruB_N 96 SAvkvnGkrlyelaregeeverkkrkvtiyelelleveepevelevecsk 145 S ++ +++++y+la +g + i +++l +++ p++ le+ c + tr|H2YML1|H2YML1_CIOSA 188 SGLELSSHQAYKLASRGLLRPKGGYEPVIVDIKLSSLNLPHFVLEIICIN 237 **********************************************9965 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (149 nodes) Target sequences: 11592 (4231397 residues searched) Passed MSV filter: 344 (0.0296756); expected 231.8 (0.02) Passed bias filter: 249 (0.0214803); expected 231.8 (0.02) Passed Vit filter: 14 (0.00120773); expected 11.6 (0.001) Passed Fwd filter: 2 (0.000172533); expected 0.1 (1e-05) Initial search space (Z): 11592 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.07u 0.00s 00:00:00.07 Elapsed: 00:00:00.04 # Mc/sec: 15761.95 // [ok]