# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TruB_N.hmm.txt
# target sequence database: proteomes/Drosophila_melanogaster.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TruB_N [M=149]
Accession: PF01509.17
Description: TruB family pseudouridylate synthase (N terminal domain)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.8e-22 79.3 0.2 2.5e-19 69.7 0.2 3.4 1 sp|O44081|DKC1_DROME H/ACA ribonucleoprotein complex subun
2.6e-09 37.2 0.0 4.7e-09 36.4 0.0 1.3 1 tr|Q29QN4|Q29QN4_DROME IP08469p OS=Drosophila melanogaster O
------ inclusion threshold ------
0.033 14.2 0.9 1 9.4 0.0 2.3 2 tr|Q9V3A8|Q9V3A8_DROME Ergic53, isoform A OS=Drosophila mela
0.13 12.3 0.0 0.16 11.9 0.0 1.1 1 tr|A1ZAJ6|A1ZAJ6_DROME GEO02592p1 OS=Drosophila melanogaster
Domain annotation for each sequence (and alignments):
>> sp|O44081|DKC1_DROME H/ACA ribonucleoprotein complex subunit 4 OS=Drosophila melanogaster OX=7227 GN=Nop60B PE=1 SV=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 69.7 0.2 7.4e-23 2.5e-19 1 149 [] 108 224 .. 108 224 .. 0.88
Alignments for each domain:
== domain 1 score: 69.7 bits; conditional E-value: 7.4e-23
HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE- CS
TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeie 89
k++lk++k Gh+GtLDp++tG+L+v++++aT+l+++ ++a KeY+a ++l+ + ++ k+++ l+k++G++
sp|O44081|DKC1_DROME 108 KKILKVEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQSAGKEYVAIFKLHGAVESVA-----------------KVRQGLEKLRGALF 179
89************************************************98877653.................68999********* PP
--------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS
TruB_N 90 qvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149
q+pp +SAvk r+ r t+y+ +ll+++e + v+c++G+Yi
sp|O44081|DKC1_DROME 180 QRPPLISAVK-----------------RQLRVRTVYDSKLLDYDETrnMGVFWVSCEAGSYI 224
**********.................77788888888888887665566778888888887 PP
>> tr|Q29QN4|Q29QN4_DROME IP08469p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG7849 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 36.4 0.0 1.4e-12 4.7e-09 18 147 .. 109 240 .. 103 241 .. 0.93
Alignments for each domain:
== domain 1 score: 36.4 bits; conditional E-value: 1.4e-12
T-EEEEEEEEGGGGGGHHHCTTS-..EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE-------------- CS
TruB_N 18 latGvLvvavgeaTklleyllead..KeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeieqvppmySAvkvnG 102
+GvL+ +++++ ++++ +++ + Y+ +lg++t+++ + +++ +++ ++++ +++++++++++ + ++ + v+ +
tr|Q29QN4|Q29QN4_DROME 109 HTSGVLLFGINRGAGQSSSIRKNRpvRVYHLIGHLGIATENNLPDSRVIMRSNHRHVSADRISSLAASMQASHQRKMFELCGVDLQT 195
679*********99999999877668***********************9988********************************** PP
-------------------EEEEEEEEEEEEEEEEEEEEEESTTT CS
TruB_N 103 krlyelaregeeverkkrkvtiyelelleveepevelevecskGt 147
+++yela +g + +y ++l+++++p+++le++ + t
tr|Q29QN4|Q29QN4_DROME 196 QEAYELACRGLLRPADDSQPVVYGIKLIHFDRPHFTLELHAINET 240
*************************************99876655 PP
>> tr|Q9V3A8|Q9V3A8_DROME Ergic53, isoform A OS=Drosophila melanogaster OX=7227 GN=ergic53 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 9.4 0.0 0.00029 1 77 114 .. 137 174 .. 112 178 .. 0.78
2 ? 0.3 2.8 0.18 6.1e+02 35 84 .. 273 322 .. 263 332 .. 0.82
Alignments for each domain:
== domain 1 score: 9.4 bits; conditional E-value: 0.00029
HHHHHHHC-EEE-------------------------- CS
TruB_N 77 leevlkkftGeieqvppmySAvkvnGkrlyelaregee 114
l ++++f + + p +SAv +G++ly+ a g++
tr|Q9V3A8|Q9V3A8_DROME 137 LAIMFDSFDNDNKHNNPYISAVLNDGTKLYDHAEDGTT 174
5667899**************************99975 PP
== domain 2 score: 0.3 bits; conditional E-value: 0.18
HHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC CS
TruB_N 35 eylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkf 84
e l+++ KeY+ +++ +++ ++D+ e +ee++e++ e++ ++ l+++
tr|Q9V3A8|Q9V3A8_DROME 273 EKLTQEYKEYQDKLEKQKQEYKKDHPDEHKDEEDWEEFYESENQRELRQI 322
5688999*******************999999889999888877777665 PP
>> tr|A1ZAJ6|A1ZAJ6_DROME GEO02592p1 OS=Drosophila melanogaster OX=7227 GN=Dmel\CG15919 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.9 0.0 4.7e-05 0.16 9 45 .. 43 78 .. 37 88 .. 0.86
Alignments for each domain:
== domain 1 score: 11.9 bits; conditional E-value: 4.7e-05
EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEE CS
TruB_N 9 vGhtGtLDplatGvLvvavgeaTklleylleadKeYe 45
v ht tLDp+a G v + + ++y + K Ye
tr|A1ZAJ6|A1ZAJ6_DROME 43 VSHTDTLDPQADGFWVNKTTWNARWVKYWRAK-KIYE 78
88************999999999999998755.7776 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (149 nodes)
Target sequences: 13786 (7394964 residues searched)
Passed MSV filter: 478 (0.0346729); expected 275.7 (0.02)
Passed bias filter: 280 (0.0203105); expected 275.7 (0.02)
Passed Vit filter: 24 (0.0017409); expected 13.8 (0.001)
Passed Fwd filter: 5 (0.000362687); expected 0.1 (1e-05)
Initial search space (Z): 13786 [actual number of targets]
Domain search space (domZ): 4 [number of targets reported over threshold]
# CPU time: 0.11u 0.01s 00:00:00.12 Elapsed: 00:00:00.07
# Mc/sec: 15740.71
//
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