# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TruB_N.hmm.txt # target sequence database: proteomes/Macaca_mulatta.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TruB_N [M=149] Accession: PF01509.17 Description: TruB family pseudouridylate synthase (N terminal domain) Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-50 170.8 0.1 4.5e-50 170.1 0.1 1.3 1 tr|F7FWZ2|F7FWZ2_MACMU Putative tRNA pseudouridine synthase 6.7e-28 98.2 0.0 9.2e-28 97.7 0.0 1.2 1 tr|F7BVF3|F7BVF3_MACMU TruB pseudouridine synthase family me 1e-21 78.1 0.1 1.8e-18 67.6 0.1 3.5 1 tr|F6W1E4|F6W1E4_MACMU Uncharacterized protein OS=Macaca mul ------ inclusion threshold ------ 0.5 11.0 2.6 0.71 10.5 1.8 1.7 1 tr|F6V0R2|F6V0R2_MACMU Transforming acidic coiled-coil conta Domain annotation for each sequence (and alignments): >> tr|F7FWZ2|F7FWZ2_MACMU Putative tRNA pseudouridine synthase 1 OS=Macaca mulatta OX=9544 GN=TRUB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 170.1 0.1 8.5e-54 4.5e-50 1 149 [] 106 255 .. 106 255 .. 0.98 Alignments for each domain: == domain 1 score: 170.1 bits; conditional E-value: 8.5e-54 HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EE CS TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGe 87 kr+ ++ k+Gh+GtLD +a GvLvv++g++Tk+l+++l+ +K+Y+a +lg++tdt D++g+++ee+ ++k+t+e++e +l+kftG+ tr|F7FWZ2|F7FWZ2_MACMU 106 KRKKQTLKIGHGGTLDSAARGVLVVGIGSGTKMLTSMLSGSKRYIAIGELGKATDTLDSTGKVTEEKPYDKITQEDIEGILQKFTGN 192 5677888***********************************************************99******************* PP E-------------------------------.--EEEEEEEEEEEEEEEEEEEEEESTTTTH CS TruB_N 88 ieqvppmySAvkvnGkrlyelaregeeverkk.rkvtiyelelleveepevelevecskGtYi 149 i+qvpp ySA+k++G+rl +l+++ge ve k+ r+vt+y+++l ++++p ++l+vec G+Yi tr|F7FWZ2|F7FWZ2_MACMU 193 IMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPaRPVTVYSISLQKFQPPFFTLDVECGGGFYI 255 *****************************8877*****************************8 PP >> tr|F7BVF3|F7BVF3_MACMU TruB pseudouridine synthase family member 2 OS=Macaca mulatta OX=9544 GN=TRUB2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 97.7 0.0 1.7e-31 9.2e-28 6 148 .. 88 232 .. 84 233 .. 0.96 Alignments for each domain: == domain 1 score: 97.7 bits; conditional E-value: 1.7e-31 -S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-..EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE-- CS TruB_N 6 akkvGhtGtLDplatGvLvvavgeaTklleyllead..KeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeieq 90 kvG ++ LD a+GvLv++vg++++ll+ + +a+ K Y++ lg++td+ ++g+ +e+++++++t+ekl+++l++++G+ ++ tr|F7BVF3|F7BVF3_MACMU 88 HLKVGMGHRLDVRASGVLVLGVGHGCRLLTDMYNAHltKDYTVRGLLGKATDDFCEDGRLVEKTTYDHVTREKLDRILAMIQGSHQK 174 569***************************99977666*************************99********************** PP -------------------------------EEEEEEEEEEEEEEEEEEEEEESTTTT CS TruB_N 91 vppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveepevelevecskGtY 148 myS+++ + +++ye+a +g ++k ++ i+ +++l++ +pe+ lev+c + t+ tr|F7BVF3|F7BVF3_MACMU 175 ALVMYSNLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLHFAPPEFLLEVQCMHETQ 232 *****************************************************99885 PP >> tr|F6W1E4|F6W1E4_MACMU Uncharacterized protein OS=Macaca mulatta OX=9544 GN=DKC1 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.6 0.1 3.4e-22 1.8e-18 1 149 [] 112 228 .. 112 228 .. 0.92 Alignments for each domain: == domain 1 score: 67.6 bits; conditional E-value: 3.4e-22 HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EE CS TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGe 87 +r+l+++k Gh+GtLDp++tG+L+v++++aT+l+++ ++a KeY+ +rl+ + + +l+++l+++tG+ tr|F6W1E4|F6W1E4_MACMU 112 RRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGT-----------------QLSRALETLTGA 181 89************************************************99876653.................5899******** PP E---------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS TruB_N 88 ieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149 + q+pp ++Avk r+ r tiye +++e++++ + v+c++GtYi tr|F6W1E4|F6W1E4_MACMU 182 LFQRPPLIAAVK-----------------RQLRVRTIYESKMIEYDPErrLGIFWVSCEAGTYI 228 ************.................89999999999999998876567799999999998 PP >> tr|F6V0R2|F6V0R2_MACMU Transforming acidic coiled-coil containing protein 3 OS=Macaca mulatta OX=9544 GN=TACC3 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 1.8 0.00013 0.71 59 130 .. 710 778 .. 696 798 .. 0.82 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00013 TTS-EEE-.--TT--HHHHHHHHHHC-EEE---------------------------------EEEEEEEEE CS TruB_N 59 aegeileeekveklteekleevlkkftGeieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelell 130 +++e++e + +ee+l+++++++ +i+q y A+k + ++ +la e+++ r+k + ++ +l+ tr|F6V0R2|F6V0R2_MACMU 710 KQKEVIEG---YRKNEESLKKCVEDYLAKITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEVLALQAS 778 55555554...467899***************************************9999999999888764 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (149 nodes) Target sequences: 21211 (10888574 residues searched) Passed MSV filter: 639 (0.0301259); expected 424.2 (0.02) Passed bias filter: 460 (0.0216869); expected 424.2 (0.02) Passed Vit filter: 32 (0.00150865); expected 21.2 (0.001) Passed Fwd filter: 4 (0.000188581); expected 0.2 (1e-05) Initial search space (Z): 21211 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.07 # Mc/sec: 23177.11 // [ok]