# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TruB_N.hmm.txt # target sequence database: proteomes/Monodelphis_domestica.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TruB_N [M=149] Accession: PF01509.17 Description: TruB family pseudouridylate synthase (N terminal domain) Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-51 175.0 0.2 2.4e-51 174.2 0.2 1.4 1 tr|F6SH34|F6SH34_MONDO TruB pseudouridine synthase family me 5.3e-26 92.0 0.1 7.4e-26 91.5 0.1 1.2 1 tr|F6WW62|F6WW62_MONDO Uncharacterized protein OS=Monodelphi 5.7e-21 75.7 4.2 3.2e-19 70.0 0.1 3.6 2 tr|F7EDM7|F7EDM7_MONDO Dyskerin pseudouridine synthase 1 OS= Domain annotation for each sequence (and alignments): >> tr|F6SH34|F6SH34_MONDO TruB pseudouridine synthase family member 1 OS=Monodelphis domestica OX=13616 GN=TRUB1 PE=3 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 174.2 0.2 3.5e-55 2.4e-51 1 149 [] 119 268 .. 119 268 .. 0.97 Alignments for each domain: == domain 1 score: 174.2 bits; conditional E-value: 3.5e-55 HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EE CS TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGe 87 kr+ +a k+Gh+GtLD +atGvLvv++g++Tk+l+++l+ +K+Y+at +lg++tdt D++g+i+ee+ ++++++e++e +l+kftG+ tr|F6SH34|F6SH34_MONDO 119 KRKKQALKIGHGGTLDSAATGVLVVGIGKGTKMLTSMLSGSKKYIATGELGKATDTLDSTGKITEEKPYDQIKQEDIEGILQKFTGN 205 5667788***********************************************************99******************* PP E-------------------------------.--EEEEEEEEEEEEEEEEEEEEEESTTTTH CS TruB_N 88 ieqvppmySAvkvnGkrlyelaregeeverkk.rkvtiyelelleveepevelevecskGtYi 149 i+qvpp ySA+k++G+rl +l+++ge ve k+ r+vt+y+l+l ++++p ++l+vec G+Yi tr|F6SH34|F6SH34_MONDO 206 IMQVPPLYSALKKDGQRLSTLMKKGEVVEAKPaRPVTVYSLSLQKFQPPLFTLDVECGGGFYI 268 *****************************8877*****************************8 PP >> tr|F6WW62|F6WW62_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 91.5 0.1 1e-29 7.4e-26 6 147 .. 88 231 .. 82 233 .. 0.96 Alignments for each domain: == domain 1 score: 91.5 bits; conditional E-value: 1e-29 -S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-..EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE-- CS TruB_N 6 akkvGhtGtLDplatGvLvvavgeaTklleyllead..KeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeieq 90 kvG ++ LD +++GvLv++vg++ kll+ +++a+ K Y++ lg++td+ eg+ +e+++++++t+ekl+++l+ ++G+ ++ tr|F6WW62|F6WW62_MONDO 88 SVKVGVGHRLDVKSSGVLVLGVGRGNKLLTDIHNAHltKDYTVRGLLGKATDDFTDEGRLIEKTTYDHITQEKLSRILAVIQGSHQK 174 45******************************987666*************************99********************** PP -------------------------------EEEEEEEEEEEEEEEEEEEEEESTTT CS TruB_N 91 vppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveepevelevecskGt 147 m+S+++ + +++ye+a +g + k ++ i+ +++l++ +pe+ le++c + t tr|F6WW62|F6WW62_MONDO 175 ALVMHSNLNLKTQEAYEMAVKGLIRPMCKTPMLITGIRCLQFAPPEFLLEIQCMHET 231 *****************************************************9987 PP >> tr|F7EDM7|F7EDM7_MONDO Dyskerin pseudouridine synthase 1 OS=Monodelphis domestica OX=13616 GN=DKC1 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.0 0.1 4.5e-23 3.2e-19 1 149 [] 110 226 .. 110 226 .. 0.93 2 ? -4.4 1.0 3 2.1e+04 54 81 .. 479 492 .. 466 502 .. 0.46 Alignments for each domain: == domain 1 score: 70.0 bits; conditional E-value: 4.5e-23 HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EE CS TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGe 87 +r+l+++k Gh+GtLDp++tG+L+v++++aT+l+++ ++a KeY+ +irl+ + ++e +l+++l+++tG+ tr|F7EDM7|F7EDM7_MONDO 110 RRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGVIRLHNAIESEV-----------------QLSRALETLTGA 179 89************************************************99877653.................6899******** PP E---------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS TruB_N 88 ieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149 + q+pp ++Avk r+ r tiye ++le++++ + v+c++GtYi tr|F7EDM7|F7EDM7_MONDO 180 LFQRPPLIAAVK-----------------RQLRVRTIYESKMLEYDPEkrLGIFWVSCEAGTYI 226 ************.................8999999*******9988765678999******98 PP == domain 2 score: -4.4 bits; conditional E-value: 3 ETTSBTTS-EEE-.--TT--HHHHHHHH CS TruB_N 54 tdteDaegeileeekveklteekleevl 81 +++D+e e+ e+ + tr|F7EDM7|F7EDM7_MONDO 479 EEQDDSEEEVEEK--------------M 492 2233333333332..............2 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (149 nodes) Target sequences: 21272 (11266248 residues searched) Passed MSV filter: 752 (0.0353516); expected 425.4 (0.02) Passed bias filter: 459 (0.0215777); expected 425.4 (0.02) Passed Vit filter: 25 (0.00117525); expected 21.3 (0.001) Passed Fwd filter: 4 (0.000188041); expected 0.2 (1e-05) Initial search space (Z): 21272 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.16u 0.01s 00:00:00.17 Elapsed: 00:00:00.08 # Mc/sec: 20983.39 // [ok]