# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TruB_N.hmm.txt
# target sequence database: proteomes/Nematostella_vectensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TruB_N [M=149]
Accession: PF01509.17
Description: TruB family pseudouridylate synthase (N terminal domain)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2e-51 174.7 0.5 2.4e-51 174.4 0.5 1.1 1 tr|A7T9C1|A7T9C1_NEMVE Predicted protein (Fragment) OS=Nemat
1.7e-23 84.1 0.3 2.3e-20 73.9 0.3 3.1 1 tr|A7RTE5|A7RTE5_NEMVE Predicted protein (Fragment) OS=Nemat
------ inclusion threshold ------
0.069 14.0 0.5 0.17 12.7 0.1 1.8 2 tr|A7SID0|A7SID0_NEMVE Predicted protein OS=Nematostella vec
0.12 13.2 0.5 10 6.9 0.1 2.1 2 tr|A7SRI2|A7SRI2_NEMVE Predicted protein OS=Nematostella vec
2.4 9.0 6.8 0.3 11.9 2.7 1.6 2 tr|A7SA54|A7SA54_NEMVE Predicted protein OS=Nematostella vec
Domain annotation for each sequence (and alignments):
>> tr|A7T9C1|A7T9C1_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g5335 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 174.4 0.5 5e-55 2.4e-51 8 149 .] 2 143 .. 1 143 [. 0.99
Alignments for each domain:
== domain 1 score: 174.4 bits; conditional E-value: 5e-55
-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE------ CS
TruB_N 8 kvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeieqvppm 94
kvGh+GtLDpla+G+L++++g++Tk ++ ++ + KeY+ t+++g +t ++D e e+ ++ +++++t+e ++++ ++f G+i+q+pp+
tr|A7T9C1|A7T9C1_NEMVE 2 KVGHAGTLDPLASGLLIICTGKQTKNISEYQGQVKEYTGTFTIGSTTPSYDLETEVNQTFSTTHITKELIHKTTEQFIGSIQQQPPI 88
9**********************************************************779************************* PP
---------------------------EEEEEEEEEEEEEEEEEEEEEESTTTTH CS
TruB_N 95 ySAvkvnGkrlyelaregeeverkkrkvtiyelelleveepevelevecskGtYi 149
+SA+k++Gkrlyelar+ge++e+++r++ti+e+e++++++ +++++v cskGtYi
tr|A7T9C1|A7T9C1_NEMVE 89 FSALKKDGKRLYELARKGETTEIPTREITISEFEITSIDRLKIDFRVVCSKGTYI 143
******************************************************9 PP
>> tr|A7RTE5|A7RTE5_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g92827 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 73.9 0.3 4.6e-24 2.3e-20 1 149 [] 82 198 .. 82 198 .. 0.93
Alignments for each domain:
== domain 1 score: 73.9 bits; conditional E-value: 4.6e-24
HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EE CS
TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGe 87
+r+l+++k Gh+GtLDp++tG+L+v++++aT+l+++ + a KeY++ +rl+ + + + ++l ++++++tG+
tr|A7RTE5|A7RTE5_NEMVE 82 RRILRVEKTGHSGTLDPKVTGCLIVCIDKATRLVKSQQGAGKEYVCIVRLHNAIEGQ-----------------AELAKTIETLTGA 151
89************************************************9887654.................3588999****** PP
E---------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS
TruB_N 88 ieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149
+ q+pp +SAvk r+ r tiye +lle++++ + v+c++GtYi
tr|A7RTE5|A7RTE5_NEMVE 152 LFQRPPLISAVK-----------------RQLRIRTIYESKLLEYDDErhLGVFWVSCEAGTYI 198
************.................999*************9886677899********8 PP
>> tr|A7SID0|A7SID0_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g212735 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.8 0.0 2 9.9e+03 58 84 .. 144 171 .. 122 182 .. 0.50
2 ? 12.7 0.1 3.5e-05 0.17 20 76 .. 229 284 .. 226 300 .. 0.82
Alignments for each domain:
== domain 1 score: -2.8 bits; conditional E-value: 2
BTTS-EEE-..--TT--HHHHHHHHHHC CS
TruB_N 58 Daegeilee.ekveklteekleevlkkf 84
D + + ++ +++ ++e+++ v++++
tr|A7SID0|A7SID0_NEMVE 144 DCDFSVAASeLTAAVHEKEDMQGVVASL 171
3333333221112222334444444444 PP
== domain 2 score: 12.7 bits; conditional E-value: 3.5e-05
EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHH CS
TruB_N 20 tGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteek 76
+G+ + ++a k++e + +++K +++++l ++ +t+D+e e+l+e+ +e+ ++k
tr|A7SID0|A7SID0_NEMVE 229 KGLVALQAENAAKIAELMDSTSKLADVNAELVEAANTKDEEIEMLREQ-LEHARKKK 284
799999**************************************9883.55544433 PP
>> tr|A7SRI2|A7SRI2_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g128867 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 6.9 0.1 0.0021 10 40 66 .. 9 35 .. 4 55 .. 0.76
2 ? 5.5 0.1 0.0055 27 40 61 .. 55 76 .. 39 81 .. 0.86
Alignments for each domain:
== domain 1 score: 6.9 bits; conditional E-value: 0.0021
S-EEEEEEEEETEEETTSBTTS-EEE- CS
TruB_N 40 adKeYeatirlgaetdteDaegeilee 66
+++eY++ +r g +t t+D + + +
tr|A7SRI2|A7SRI2_NEMVE 9 EHREYDTDMRHGHSTPTYDIDMRHGHD 35
579****************98876554 PP
== domain 2 score: 5.5 bits; conditional E-value: 0.0055
S-EEEEEEEEETEEETTSBTTS CS
TruB_N 40 adKeYeatirlgaetdteDaeg 61
+++eY++ +r g +t t+D +
tr|A7SRI2|A7SRI2_NEMVE 55 EHREYDTDMRHGHSTPTYDIDM 76
579****************875 PP
>> tr|A7SA54|A7SA54_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g232931 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.6 0.1 1.8 8.7e+03 64 80 .. 18 34 .. 4 50 .. 0.52
2 ? 11.9 2.7 6.2e-05 0.3 29 109 .. 97 180 .. 95 201 .. 0.74
Alignments for each domain:
== domain 1 score: -2.6 bits; conditional E-value: 1.8
EE-.--TT--HHHHHHH CS
TruB_N 64 leeekveklteekleev 80
l+++ e+++++++++
tr|A7SA54|A7SA54_NEMVE 18 LRRQLQEEVNKASIQSR 34
33333344444444433 PP
== domain 2 score: 11.9 bits; conditional E-value: 6.2e-05
GGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-....--TT--HHHHHHHHHHC-EEE--------------------- CS
TruB_N 29 eaTklleylleadKeYeatirlgaetdteDaegeilee...ekveklteekleevlkkftGeieqvppmySAvkvnGkrlyela 109
++Tkll++l+ K+ +a+ + + + +D++ i + + e+ +++kl+e+l+ + + +q m S ++ ++l ++
tr|A7SA54|A7SA54_NEMVE 97 STTKLLRHLQGRVKQLRAQNESMRSDSLNDSQTSIYSDsvdNLDETAKTKKLQEALQVSEQRAQQNSAMLSQKMMEMTKLQKML 180
68*********************************9874422233335556777777777777777777777777766666654 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (149 nodes)
Target sequences: 24428 (8257945 residues searched)
Passed MSV filter: 685 (0.0280416); expected 488.6 (0.02)
Passed bias filter: 471 (0.0192812); expected 488.6 (0.02)
Passed Vit filter: 34 (0.00139185); expected 24.4 (0.001)
Passed Fwd filter: 5 (0.000204683); expected 0.2 (1e-05)
Initial search space (Z): 24428 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.12u 0.01s 00:00:00.13 Elapsed: 00:00:00.06
# Mc/sec: 20507.23
//
[ok]