# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TruB_N.hmm.txt # target sequence database: proteomes/Pan_troglodytes.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TruB_N [M=149] Accession: PF01509.17 Description: TruB family pseudouridylate synthase (N terminal domain) Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-50 171.0 0.1 3.9e-50 170.4 0.1 1.2 1 tr|K7CFC2|K7CFC2_PANTR TRUB1 isoform 1 OS=Pan troglodyt 1.4e-27 97.3 0.0 1.9e-27 96.8 0.0 1.2 1 tr|H2QXY8|H2QXY8_PANTR TRUB2 isoform 1 OS=Pan troglodyt 1.1e-21 78.2 0.1 1.9e-18 67.6 0.1 3.5 1 tr|K7CJN9|K7CJN9_PANTR DKC1 isoform 1 OS=Pan troglodyte 2e-21 77.3 0.1 2.4e-18 67.3 0.1 3.4 1 tr|A0A2I3S0W4|A0A2I3S0W4_PANTR Uncharacterized protein OS=Pan t Domain annotation for each sequence (and alignments): >> tr|K7CFC2|K7CFC2_PANTR TRUB1 isoform 1 OS=Pan troglodytes OX=9598 GN=TRUB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 170.4 0.1 6.8e-54 3.9e-50 1 149 [] 106 255 .. 106 255 .. 0.98 Alignments for each domain: == domain 1 score: 170.4 bits; conditional E-value: 6.8e-54 HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EE CS TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGe 87 kr+ ++ k+Gh+GtLD +a GvLvv++g++Tk+l+++l+ +K+Y+a +lg++tdt D++g+++ee+ ++k+t+e++e +l+kftG+ tr|K7CFC2|K7CFC2_PANTR 106 KRKKQTLKIGHGGTLDSAARGVLVVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGKVTEEKPYDKITQEDIEGILQKFTGN 192 5677888***********************************************************99******************* PP E-------------------------------.--EEEEEEEEEEEEEEEEEEEEEESTTTTH CS TruB_N 88 ieqvppmySAvkvnGkrlyelaregeeverkk.rkvtiyelelleveepevelevecskGtYi 149 i+qvpp ySA+k++G+rl +l+++ge ve k+ r+vt+y+++l ++++p ++l+vec G+Yi tr|K7CFC2|K7CFC2_PANTR 193 IMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPaRPVTVYSISLQKFQPPFFTLDVECGGGFYI 255 *****************************8877*****************************8 PP >> tr|H2QXY8|H2QXY8_PANTR TRUB2 isoform 1 OS=Pan troglodytes OX=9598 GN=TRUB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.8 0.0 3.3e-31 1.9e-27 6 148 .. 88 232 .. 84 233 .. 0.96 Alignments for each domain: == domain 1 score: 96.8 bits; conditional E-value: 3.3e-31 -S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-..EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE-- CS TruB_N 6 akkvGhtGtLDplatGvLvvavgeaTklleyllead..KeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeieq 90 kvG ++ LD +a+GvLv++vg++++ll+ + +a+ K Y++ lg++td+ ++g+ +e+++++++t+ekl+++l+ ++G+ ++ tr|H2QXY8|H2QXY8_PANTR 88 HLKVGVGHRLDAQASGVLVLGVGHGCRLLTDMYNAHltKDYTVRGLLGKATDDFREDGRLVEKTTYDHVTREKLDRILAVIQGSHQK 174 569***************************99977666*************************99********************** PP -------------------------------EEEEEEEEEEEEEEEEEEEEEESTTTT CS TruB_N 91 vppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveepevelevecskGtY 148 myS+++ + +++ye+a +g ++k ++ i+ +++l + +pe+ lev+c + t+ tr|H2QXY8|H2QXY8_PANTR 175 ALVMYSNLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLYFAPPEFLLEVQCMHETQ 232 *****************************************************99885 PP >> tr|K7CJN9|K7CJN9_PANTR DKC1 isoform 1 OS=Pan troglodytes OX=9598 GN=DKC1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.6 0.1 3.3e-22 1.9e-18 1 149 [] 110 226 .. 110 226 .. 0.92 Alignments for each domain: == domain 1 score: 67.6 bits; conditional E-value: 3.3e-22 HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EE CS TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGe 87 +r+l+++k Gh+GtLDp++tG+L+v++++aT+l+++ ++a KeY+ +rl+ + + +l+++l+++tG+ tr|K7CJN9|K7CJN9_PANTR 110 RRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGT-----------------QLSRALETLTGA 179 89************************************************99876653.................5899******** PP E---------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS TruB_N 88 ieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149 + q+pp ++Avk r+ r tiye +++e++++ + v+c++GtYi tr|K7CJN9|K7CJN9_PANTR 180 LFQRPPLIAAVK-----------------RQLRVRTIYESKMIEYDPErrLGIFWVSCEAGTYI 226 ************.................89999999999999998876567799999999998 PP >> tr|A0A2I3S0W4|A0A2I3S0W4_PANTR Uncharacterized protein OS=Pan troglodytes OX=9598 GN=DKC1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.3 0.1 4.2e-22 2.4e-18 1 149 [] 191 307 .. 191 307 .. 0.92 Alignments for each domain: == domain 1 score: 67.3 bits; conditional E-value: 4.2e-22 HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHH CS TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteeklee 79 +r+l+++k Gh+GtLDp++tG+L+v++++aT+l+++ ++a KeY+ +rl+ + + +l++ tr|A0A2I3S0W4|A0A2I3S0W4_PANTR 191 RRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGT-----------------QLSR 252 89************************************************99876653.................5899 PP HHHHC-EEE---------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS TruB_N 80 vlkkftGeieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149 +l+++tG++ q+pp ++Avk r+ r tiye +++e++++ + v+c++GtYi tr|A0A2I3S0W4|A0A2I3S0W4_PANTR 253 ALETLTGALFQRPPLIAAVK-----------------RQLRVRTIYESKMIEYDPErrLGIFWVSCEAGTYI 307 ********************.................89999999999999998876567799999999998 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (149 nodes) Target sequences: 23008 (11942255 residues searched) Passed MSV filter: 671 (0.0291638); expected 460.2 (0.02) Passed bias filter: 481 (0.0209058); expected 460.2 (0.02) Passed Vit filter: 34 (0.00147775); expected 23.0 (0.001) Passed Fwd filter: 4 (0.000173853); expected 0.2 (1e-05) Initial search space (Z): 23008 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.07 # Mc/sec: 25419.94 // [ok]