# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TruB_N.hmm.txt
# target sequence database: proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TruB_N [M=149]
Accession: PF01509.17
Description: TruB family pseudouridylate synthase (N terminal domain)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.5e-41 140.7 0.1 1.2e-39 134.5 0.0 2.6 2 sp|P48567|PUS4_YEAST tRNA pseudouridine synthase 4 OS=Saccha
3.8e-20 71.2 9.7 1.6e-19 69.2 0.0 4.1 2 sp|P33322|CBF5_YEAST H/ACA ribonucleoprotein complex subunit
Domain annotation for each sequence (and alignments):
>> sp|P48567|PUS4_YEAST tRNA pseudouridine synthase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 134.5 0.0 4e-43 1.2e-39 3 131 .. 62 193 .. 57 202 .. 0.90
2 ? 3.3 0.0 0.011 33 130 149 .] 266 285 .. 239 285 .. 0.79
Alignments for each domain:
== domain 1 score: 134.5 bits; conditional E-value: 4e-43
HTT-S-EEESS---TT-EEEEEEEEGGGGG.GHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE-- CS
TruB_N 3 llkakkvGhtGtLDplatGvLvvavgeaTk.lleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeieq 90
+++ k+Gh+GtLDpla+GvLv+++g +Tk l++yl+ + K Ye ++ +g++t++ D egeil++++v++l+ ++l++v +kf G+++q
sp|P48567|PUS4_YEAST 62 KVSKVKMGHGGTLDPLASGVLVIGIGAGTKkLANYLSGTVKVYESEALFGVSTTSGDVEGEILSQNSVKHLNFDDLKTVEEKFVGQLKQ 150
344569***********************73667777888*************************99********************** PP
--------------------------..-----EEEEEEEEEE CS
TruB_N 91 vppmySAvkvnGkrlyelaregeeve..rkkrkvtiyelelle 131
+pp+y+A+k++Gk+l+e+areg+ + +++r+vtiy+l++++
sp|P48567|PUS4_YEAST 151 TPPIYAALKMDGKPLHEYAREGKPLPraIEPRQVTIYDLKVFS 193
**********************988733689********9976 PP
== domain 2 score: 3.3 bits; conditional E-value: 0.011
EEEEEEEEEEEEEESTTTTH CS
TruB_N 130 leveepevelevecskGtYi 149
+++ p++++++++s+GtYi
sp|P48567|PUS4_YEAST 266 DSYRAPKLHFKANVSSGTYI 285
567889*************8 PP
>> sp|P33322|CBF5_YEAST H/ACA ribonucleoprotein complex subunit CBF5 OS=Saccharomyces cerevisiae (strain ATCC 204508 /
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 69.2 0.0 5.4e-23 1.6e-19 1 149 [] 80 196 .. 80 196 .. 0.87
2 ? -5.9 6.2 2 6e+03 42 80 .. 384 420 .. 368 462 .. 0.57
Alignments for each domain:
== domain 1 score: 69.2 bits; conditional E-value: 5.4e-23
HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE- CS
TruB_N 1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeie 89
kr+l+ +k Gh+GtLDp++tG+L+v++++aT+l+++ + a KeY++ +rl+ + ++e +l + l+++tG++
sp|P33322|CBF5_YEAST 80 KRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHDALKDEK-----------------DLGRSLENLTGALF 151
89************************************************98876544.................57888999****** PP
--------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS
TruB_N 90 qvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149
q+pp +SAvk r+ r tiye +l+e++++ + ++c++GtY+
sp|P33322|CBF5_YEAST 152 QRPPLISAVK-----------------RQLRVRTIYESNLIEFDNKrnLGVFWASCEAGTYM 196
**********.................77788888888888887665556777888888885 PP
== domain 2 score: -5.9 bits; conditional E-value: 2
EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHH CS
TruB_N 42 KeYeatirlgaetdteDaegeileeekveklteekleev 80
KeY+ + ++t++ +++e+ ee +k +e++l +
sp|P33322|CBF5_YEAST 384 KEYVPLDNAEQSTSSSQETKETEEE--PKKAKEDSLIKE 420
6666555555555555544444444..233333333322 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (149 nodes)
Target sequences: 6049 (2936363 residues searched)
Passed MSV filter: 219 (0.0362043); expected 121.0 (0.02)
Passed bias filter: 141 (0.0233096); expected 121.0 (0.02)
Passed Vit filter: 15 (0.00247975); expected 6.0 (0.001)
Passed Fwd filter: 2 (0.000330633); expected 0.1 (1e-05)
Initial search space (Z): 6049 [actual number of targets]
Domain search space (domZ): 2 [number of targets reported over threshold]
# CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.02
# Mc/sec: 21875.90
//
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