# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TruB_N.hmm.txt
# target sequence database: proteomes/Tetrahymena_thermophila.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TruB_N [M=149]
Accession: PF01509.17
Description: TruB family pseudouridylate synthase (N terminal domain)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
5.9e-21 76.0 1.1 5e-18 66.5 1.1 3.2 1 tr|Q234Z5|Q234Z5_TETTS tRNA pseudouridine synthase OS=Tetrah
------ inclusion threshold ------
0.088 13.7 0.0 0.11 13.5 0.0 1.1 1 tr|Q22LR1|Q22LR1_TETTS Transmembrane protein, putative OS=Te
0.095 13.6 1.7 0.33 11.9 0.1 1.9 2 tr|Q24I92|Q24I92_TETTS Uncharacterized protein OS=Tetrahymen
0.68 10.9 3.0 21 6.0 0.1 3.9 3 tr|Q23WR6|Q23WR6_TETTS SLEI family protein OS=Tetrahymena th
0.92 10.4 5.3 8.3 7.3 3.1 3.0 2 tr|Q22BD7|Q22BD7_TETTS Tetratricopeptide repeat protein OS=T
Domain annotation for each sequence (and alignments):
>> tr|Q234Z5|Q234Z5_TETTS tRNA pseudouridine synthase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_000
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 66.5 1.1 9.4e-22 5e-18 3 149 .] 106 220 .. 104 220 .. 0.86
Alignments for each domain:
== domain 1 score: 66.5 bits; conditional E-value: 9.4e-22
HTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE- CS
TruB_N 3 llkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeie 89
++k++k Gh+GtLDp++tG+L+v++++aT+l++ ++a KeY+ +rl+ + ++e kl ++l+++tG +
tr|Q234Z5|Q234Z5_TETTS 106 ITKMEKTGHSGTLDPKVTGCLIVCLNRATRLVKAQQSAGKEYVGIVRLHNDIESE-----------------LKLAKALQQLTGPLF 175
7899********************************************9765543.................35899********** PP
--------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS
TruB_N 90 qvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149
q pp +SAvk r+ r tiye +l+e++++ + ++c++GtY+
tr|Q234Z5|Q234Z5_TETTS 176 QKPPLISAVK-----------------RELRVRTIYESKLIEYNPEkkMGIIWMSCEAGTYV 220
**********.................77788888888888887665455677888888886 PP
>> tr|Q22LR1|Q22LR1_TETTS Transmembrane protein, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.5 0.0 2e-05 0.11 16 79 .. 32 95 .. 31 107 .. 0.88
Alignments for each domain:
== domain 1 score: 13.5 bits; conditional E-value: 2e-05
-TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHH CS
TruB_N 16 DplatGvLvvavgeaTklleylleadKeYeatirlgaetdteDaegeileeekveklteeklee 79
D + G+Lv v+ T + ++e +++Y+++++l ++t D e + + e k++ ++ +++++
tr|Q22LR1|Q22LR1_TETTS 32 DSKQDGCLVTYVDFSTIDVLAMNECSQSYKFKFTLTFPSQTLDLETDCIYEGKNQIFSLDEVKN 95
66778*******************************************9885566667666664 PP
>> tr|Q24I92|Q24I92_TETTS Uncharacterized protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0103568
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.9 0.1 6.2e-05 0.33 63 118 .. 23 79 .. 8 95 .. 0.83
2 ? 1.3 0.3 0.11 5.9e+02 32 74 .. 97 140 .. 90 145 .] 0.65
Alignments for each domain:
== domain 1 score: 11.9 bits; conditional E-value: 6.2e-05
EEE-..--TT--HHHHHHHHHHC-EEE------------------------------ CS
TruB_N 63 ilee.ekveklteekleevlkkftGeieqvppmySAvkvnGkrlyelaregeeverk 118
il++ ++++++ +++++++++eie +++S+++ nG l +++ g +++r
tr|Q24I92|Q24I92_TETTS 23 ILSKyVPQYNISNTEYHSAIDTIKSEIESNQSIVSNLQSNGIALSQYMTGGSTLSRD 79
444455578999*************************************99998775 PP
== domain 2 score: 1.3 bits; conditional E-value: 0.11
GGHHHCTTS-EEEEEEEEETEE.ETTSBTTS-EEE-.--TT--H CS
TruB_N 32 klleylleadKeYeatirlgae.tdteDaegeileeekveklte 74
++++++++++K t+ + + +t D++++i +++k ++ +
tr|Q24I92|Q24I92_TETTS 97 RIIQIMEKNEKDSFQTMDMSHQfVNTLDQQQTISQKNKQFNFRQ 140
67777777777666666665442678888888877755555555 PP
>> tr|Q23WR6|Q23WR6_TETTS SLEI family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00778410 PE
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.1 0.0 1.3 6.9e+03 73 99 .. 870 896 .. 866 913 .. 0.89
2 ? 2.2 0.1 0.059 3.2e+02 73 99 .. 1941 1967 .. 1929 1974 .. 0.89
3 ? 6.0 0.1 0.0039 21 73 133 .. 2005 2065 .. 1981 2079 .. 0.89
Alignments for each domain:
== domain 1 score: -2.1 bits; conditional E-value: 1.3
-HHHHHHHHHHC-EEE----------- CS
TruB_N 73 teekleevlkkftGeieqvppmySAvk 99
+++++++++++++ ++e p ySA+
tr|Q23WR6|Q23WR6_TETTS 870 EKKMISQAIESYKKAFEINPKYYSAIG 896
57889********************95 PP
== domain 2 score: 2.2 bits; conditional E-value: 0.059
-HHHHHHHHHHC-EEE----------- CS
TruB_N 73 teekleevlkkftGeieqvppmySAvk 99
++k+ee++++++ +ie p ySA+k
tr|Q23WR6|Q23WR6_TETTS 1941 ANKKFEEAIESYKKAIEINPKCYSAIK 1967
57899*********************9 PP
== domain 3 score: 6.0 bits; conditional E-value: 0.0039
-HHHHHHHHHHC-EEE---------------------------------EEEEEEEEEEEE CS
TruB_N 73 teekleevlkkftGeieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleve 133
+++++e++++++ +ieq p SA G+ + ++ ++++e k+ +i+ ++++++
tr|Q23WR6|Q23WR6_TETTS 2005 RQNMIDEAISNYQKAIEQDPKYKSAYIQLGNSYLDKVQYDQAIECYKKALEIDPNDVIAYN 2065
5789************************************************999988876 PP
>> tr|Q22BD7|Q22BD7_TETTS Tetratricopeptide repeat protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 1.5 0.0 0.099 5.3e+02 40 78 .. 384 419 .. 377 435 .. 0.80
2 ? 7.3 3.1 0.0015 8.3 30 85 .. 581 636 .. 577 642 .. 0.91
Alignments for each domain:
== domain 1 score: 1.5 bits; conditional E-value: 0.099
S-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHH CS
TruB_N 40 adKeYeatirlgaetdteDaegeileeekveklteekle 78
+ KeYe+ +l ++ + D +g+ +e+e ++ ++k++
tr|Q22BD7|Q22BD7_TETTS 384 DLKEYETAKKLFLASLKLDDNGRLIERE---HIYNAKVK 419
569**********************984...55555554 PP
== domain 2 score: 7.3 bits; conditional E-value: 0.0015
GGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC- CS
TruB_N 30 aTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkft 85
kl ++ +e+dK+Y+ +l +e ++++++ + ++e++++kl++e+++e+++ ++
tr|Q22BD7|Q22BD7_TETTS 581 ISKLQKHQQEMDKNYDDLKKLFQEFEKKEQQPKEVQESEYDKLKKEEINEIAEIYQ 636
5799999****************************9989***********998766 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (149 nodes)
Target sequences: 26971 (16912921 residues searched)
Passed MSV filter: 2475 (0.0917652); expected 539.4 (0.02)
Passed bias filter: 894 (0.0331467); expected 539.4 (0.02)
Passed Vit filter: 73 (0.00270661); expected 27.0 (0.001)
Passed Fwd filter: 10 (0.000370769); expected 0.3 (1e-05)
Initial search space (Z): 26971 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.37u 0.02s 00:00:00.39 Elapsed: 00:00:00.14
# Mc/sec: 18000.18
//
[ok]