# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruB_N.hmm.txt
# target sequence database:        proteomes/Trichomonas_vaginalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruB_N  [M=149]
Accession:   PF01509.17
Description: TruB family pseudouridylate synthase (N terminal domain)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    4.8e-22   80.4   3.0    2.3e-13   52.2   0.0    4.0  3  tr|A2F410|A2F410_TRIVA  Pseudouridine syntase related protein
  ------ inclusion threshold ------
       0.42   12.4   0.1       0.42   12.4   0.1    3.7  4  tr|A2DJE2|A2DJE2_TRIVA  Uncharacterized protein OS=Trichomona
        1.2   10.9   2.3        9.7    8.0   0.0    2.2  2  tr|A2FHQ9|A2FHQ9_TRIVA  Uncharacterized protein OS=Trichomona


Domain annotation for each sequence (and alignments):
>> tr|A2F410|A2F410_TRIVA  Pseudouridine syntase related protein, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_4071
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   0.0   1.4e-17   2.3e-13       1      53 [.      77     129 ..      77     132 .. 0.96
   2 !   22.5   0.1   1.9e-08   0.00032      72     149 .]     130     192 ..     127     192 .. 0.90
   3 ?    1.3   0.1     0.068   1.1e+03     102     149 .]     296     343 ..     291     343 .. 0.90

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 1.4e-17
                             HHHTT-S-EEESS---TT-EEEEEEEEGGGGGGHHHCTTS-EEEEEEEEETEE CS
                  TruB_N   1 krllkakkvGhtGtLDplatGvLvvavgeaTklleylleadKeYeatirlgae 53 
                             kr+l++ k Gh+GtLDp++tG+L++++++aT + ++ ++a KeY+a++rl ++
  tr|A2F410|A2F410_TRIVA  77 KRILGVAKTGHSGTLDPKVTGCLIICIENATCIGKSQQNAGKEYVAVLRLFET 129
                             89**********************************************99765 PP

  == domain 2  score: 22.5 bits;  conditional E-value: 1.9e-08
                             --HHHHHHHHHHC-EEE---------------------------------EEEEEEEEEEEEEE..EEEEEEEESTTTTH CS
                  TruB_N  72 lteekleevlkkftGeieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveep..evelevecskGtYi 149
                             + +eklee++k +tG+++q pp++SAvk                  + r  ++y+ el+e++++   + ++v+c++GtYi
  tr|A2F410|A2F410_TRIVA 130 VPREKLEEAIKFLTGKLYQCPPAISAVK-----------------KQLRVRQVYSNELIEYDDEqkLAVMRVACEAGTYI 192
                             6789************************.................67899999*******9877668999*********8 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.068
                             --------------------EEEEEEEEEEEEEEEEEEEEEESTTTTH CS
                  TruB_N 102 GkrlyelaregeeverkkrkvtiyelelleveepevelevecskGtYi 149
                             G ++  ++ +ge++ ++  ++t +++++ + +      +v + +GtY+
  tr|A2F410|A2F410_TRIVA 296 GDQVVVITAKGEAIALAIATMTAQQMSVNQKDVAATLKRVIMDRGTYV 343
                             667777889999****************9999999999*********7 PP

>> tr|A2DJE2|A2DJE2_TRIVA  Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_136600 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1      0.49   8.1e+03      73     108 ..      66     101 ..      45     117 .. 0.71
   2 ?   -1.2   2.4      0.39   6.5e+03      30     107 ..     180     257 ..     173     268 .. 0.69
   3 ?   -2.0   0.1      0.71   1.2e+04      66      92 ..     423     448 ..     413     453 .. 0.72
   4 ?   12.4   0.1   2.5e-05      0.42      76     136 ..     493     553 ..     461     562 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.49
                             -HHHHHHHHHHC-EEE-------------------- CS
                  TruB_N  73 teekleevlkkftGeieqvppmySAvkvnGkrlyel 108
                             ++ kl++  ++f+++i+ +  + S +  + ++ly +
  tr|A2DJE2|A2DJE2_TRIVA  66 NKIKLDNKTERFQSKIKSIEIKLSHLTEEHQNLYFY 101
                             445567777888888888877777777777777655 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.39
                             GGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-.--TT--HHHHHHHHHHC-EEE------------------- CS
                  TruB_N  30 aTklleylleadKeYeatirlgaetdteDaegeileeekveklteekleevlkkftGeieqvppmySAvkvnGkrlye 107
                              Tkl++   ++ K  +++++   +t+++ ++ +i +e    + +++++++ +k++  e++ +  m+ + k + +r y+
  tr|A2DJE2|A2DJE2_TRIVA 180 DTKLMNEKIKELKDENTQLQKELRTKSQQKDIDIRTELADLSKKKKEVSNEMKDLIEEYKLQIKMFENEKNDRERRYQ 257
                             578888888888877777777777777777777766633444466667777777777777777777666666666665 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.71
                             -.--TT--HHHHHHHHHHC-EEE---- CS
                  TruB_N  66 eekveklteekleevlkkftGeieqvp 92 
                             e  +ek++++++e++ ++f+  ++++ 
  tr|A2DJE2|A2DJE2_TRIVA 423 E-MTEKIKKQRVENINNAFKAPQSKQK 448
                             3.3788999999999999988776655 PP

  == domain 4  score: 12.4 bits;  conditional E-value: 2.5e-05
                             HHHHHHHHC-EEE---------------------------------EEEEEEEEEEEEEEE CS
                  TruB_N  76 kleevlkkftGeieqvppmySAvkvnGkrlyelaregeeverkkrkvtiyelelleveepe 136
                             + ++ l+kf  e++    ++ A+k +G + y+l+ +++e++ k+ + ++ + e++e+++++
  tr|A2DJE2|A2DJE2_TRIVA 493 EAKDGLDKFLQELDAEREKVNAMKSEGSEYYNLVEKNKELKEKSEHFKVMNEEIIEMRKRK 553
                             45666777888888888889999*********************************99875 PP

>> tr|A2FHQ9|A2FHQ9_TRIVA  Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_005740 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0   0.00058       9.7      71     115 ..      24      70 ..       9      92 .. 0.73
   2 ?    1.7   1.1     0.051   8.5e+02      27      80 ..     107     161 ..     106     171 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00058
                             T--HHHHHHHH..HHC-EEE--------------------------- CS
                  TruB_N  71 klteekleevl..kkftGeieqvppmySAvkvnGkrlyelaregeev 115
                             +++ +++++++  ++ft +++ +  + S+  +nGk+ly+ +r+ + +
  tr|A2FHQ9|A2FHQ9_TRIVA  24 TFDIRDIKTIMkySRFTADQYVTLLKQSSSTINGKELYTCTRKANVT 70 
                             55566666666225789999999999***************996433 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.051
                             EGGGGGGHHHCTTS-EEEEEEEEETEEETTSBTTS-EEE-..--TT--HHHHHHH CS
                  TruB_N  27 vgeaTklleylleadKeYeatirlgaetdteDaegeilee.ekveklteekleev 80 
                             +++ T  +e+++++ K ++ + ++  e  +e++++e++++ ++ ++ +++++ + 
  tr|A2FHQ9|A2FHQ9_TRIVA 107 INDSTNKTEIFQDKCKVFQHENEIENENVSENSTKETTTNvTNENHNHSQDILTQ 161
                             677889999999999**********999999999999877544444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (149 nodes)
Target sequences:                        50190  (17055200 residues searched)
Passed MSV filter:                      1824  (0.0363419); expected 1003.8 (0.02)
Passed bias filter:                     1031  (0.0205419); expected 1003.8 (0.02)
Passed Vit filter:                        61  (0.00121538); expected 50.2 (0.001)
Passed Fwd filter:                         3  (5.97729e-05); expected 0.5 (1e-05)
Initial search space (Z):              50190  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.25u 0.01s 00:00:00.26 Elapsed: 00:00:00.11
# Mc/sec: 23102.04
//
[ok]