# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Amphimedon_queenslandica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence                       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------                       -----------
    2.6e-76  258.4   0.0    2.1e-73  248.8   0.0    2.3  2  tr|A0A1X7VCF1|A0A1X7VCF1_AMPQE  Uncharacterized protein OS=Amphi
    2.1e-55  189.5   0.0    5.7e-51  174.9   0.0    3.0  2  tr|A0A1X7U7D7|A0A1X7U7D7_AMPQE  Uncharacterized protein OS=Amphi


Domain annotation for each sequence (and alignments):
>> tr|A0A1X7VCF1|A0A1X7VCF1_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.0   0.00023         5       2      33 ..      49      81 ..      48      94 .. 0.79
   2 !  248.8   0.0   9.6e-78   2.1e-73      38     416 .]     182     584 ..     172     584 .. 0.90

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.00023
                            TruD  2 lgielyvtdt.egigGrlrespeDFiVeEieef 33
                                    +gi  yv ++   i   l++++ DFiV+Ei+ +
  tr|A0A1X7VCF1|A0A1X7VCF1_AMPQE 49 VGITEYVNKNgAQIFAILKQRYSDFIVNEISLA 81
                                    6788888754268999**************654 PP

  == domain 2  score: 248.8 bits;  conditional E-value: 9.6e-78
                            TruD  38 eakegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvg 114
                                     ++++g+y+ + + k+n+d+++++ +l++ l+++ + +++aGtKDkrA+T+Ql++ ++v p++l+++  +  ++++ ++ 
  tr|A0A1X7VCF1|A0A1X7VCF1_AMPQE 182 SKDKGDYIKFVLYKENRDSMQVITTLSKLLRVKCSVFQYAGTKDKRAITSQLVTAYRVLPSRLASIngANTNIKVGNIE 260
                                     6789***********************************************************99954448888999** PP

                            TruD 115 rarrklrlGdLaGNkFeirvrdv.aeee....eaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdl 188
                                       + +l+lGd +GN+F+i++rdv    +       ++++++l +lk+kg + NyfG+QRFG+    th +Gka+++ ++
  tr|A0A1X7VCF1|A0A1X7VCF1_AMPQE 261 YCKTPLKLGDTKGNHFTIILRDVkVPVDregeIGHHHVNSLLLSLKDKG-FINYFGMQRFGTSTIPTHAIGKALLHSEW 338
                                     **********************86433355643367999********98.***************************** PP

                            TruD 189 eeAveayvgkpfeeesedtreareavaetgdleealeelpkslry..EramlkrLae.kpkdykkAlealpknLqrlFv 264
                                     +eAv+ ++ kp e esed + +re++  t d++e l+++p + r   E ++l+ + +  +++  +Al+ lp+n + ++v
  tr|A0A1X7VCF1|A0A1X7VCF1_AMPQE 339 KEAVD-LILKPREGESEDFQVVREYYRSTSDINETLKLFPPHKRNstEYQLLRGMEKhGTTNLLAALSFLPRNARLMYV 416
                                     ****8.5779*****************************987654449********94456799*************** PP

                            TruD 265 hAyqSylFNrvlseRlerglpldepveGDvvifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelae 343
                                     h+yqSy++N+++s R++++     pv+GD+++++e      + + ++te+n ++++       + v++pl+G++++ + 
  tr|A0A1X7VCF1|A0A1X7VCF1_AMPQE 417 HSYQSYVWNQMVSFRFREYG--LVPVPGDLALQSET----VNGVLAITEENCHQYT------IFDVVLPLPGYSVQYPT 483
                                     *****************994..47*******99954....4888889998888887......6789************* PP

                            TruD 344 gevgeierevleeegleledFklpklpelsskGtrRaillrve.............................dlelsae 393
                                      +vge  +++l++++l+ ++ k +++++++  G++R+i+ +++                             +l +s  
  tr|A0A1X7VCF1|A0A1X7VCF1_AMPQE 484 NNVGEQYHRILANDNLTVDKLK-HRVKDFALPGSYRHIMAKPDnlewkllcyddvtvplhqsdldiledksfSLGTSGA 561
                                     **********************.4578****************************************987654455566 PP

                            TruD 394 edeltleFsLpkGsYATvvlrEi 416
                                     ++ l+l+FsLp+ +YAT+ lrE+
  tr|A0A1X7VCF1|A0A1X7VCF1_AMPQE 562 KRALKLSFSLPSSTYATMALREV 584
                                     667*******************6 PP

>> tr|A0A1X7U7D7|A0A1X7U7D7_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0     4e-05      0.87       3      33 ..      42      72 ..      40      84 .. 0.85
   2 !  174.9   0.0   2.6e-55   5.7e-51      42     416 .]     397     811 ..     385     811 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 4e-05
                            TruD  3 gielyvtdtegigGrlrespeDFiVeEieef 33
                                    g+e+ + + e + G l++ p DFiV+Ei + 
  tr|A0A1X7U7D7|A0A1X7U7D7_AMPQE 42 GMECAIHQGEKLKGVLKTIPADFIVTEIDKN 72
                                    899999**********************543 PP

  == domain 2  score: 174.9 bits;  conditional E-value: 2.6e-55
                            TruD  42 geylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekleikdvelevvgrarrkl 120
                                     + ++ + ++k+n +t   + +la+ l+++ +r+ faG KDk+A+T+Q ++ ++++ ++l+ ++i+++el ++     +l
  tr|A0A1X7U7D7|A0A1X7U7D7_AMPQE 397 NYFTSFSLKKENFETFLTMTKLADMLSVNPSRFAFAGSKDKKAITYQKMTAKNISMAKLAVVNIPGIELGSFEYVPCHL 475
                                     4458899************************************************************************ PP

                            TruD 121 rlGdLaGNkFeirvrdv.aeee....eaakraeeileelkekggvPNyfGvQRFGsrrpvth.....lvGkaivkgdle 189
                                     +lG+++GN+F+irvr++ + +     ++++ +e   ++l+ekg + NyfG+QRFG+     h     lvG +++ +d  
  tr|A0A1X7U7D7|A0A1X7U7D7_AMPQE 476 NLGEHQGNHFQIRVRNLeTITTngkdSLEDIIEVGCKSLEEKG-FINYFGIQRFGRL-IDDHpligpLVGYYMILDDPL 552
                                     ****************854444333333344444456777776.***********85.33333333389********** PP

                            TruD 190 eAveayvgkpfeeesedtreareavaetgdleealeelpkslryEramlkrLae...kpkdykkAlealpknLqrlFvh 265
                                     +A++++++    + + + +ea+e++++tgd++  ++++p+    E ++l++L +   ++   +k+l +lp++ +rl+++
  tr|A0A1X7U7D7|A0A1X7U7D7_AMPQE 553 NAIKVMFSPDL-TINLEAKEAKEYFTRTGDIDGTIHRMPEI-PRELMVLRNLSKygmSKFGCQKSLLSLPHQSRRLYIS 629
                                     *****998776.5566669********************86.88**********77666679***************** PP

                            TruD 266 AyqSylFNrvlseRlerglpldepveGDvvifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaeg 344
                                     +  S l+N++ s R++++   +epveGD+v+ a+++      +q++t++++ + +  ++     +++p+ G ++ l++ 
  tr|A0A1X7U7D7|A0A1X7U7D7_AMPQE 630 SLTSLLWNQMASYRIREY--GTEPVEGDLVLIANQT------VQAITSEHISSRQYSLK----DIVLPVCGHKSVLPNN 696
                                     ****************99..57***********777......77777777776664444....4789************ PP

                            TruD 345 evgeierevleeegleledFklpklpelsskGtrRaillrve..................................... 386
                                     +vg+  +e+l+  g++l +F+  +    +  G++R+++  ++                                     
  tr|A0A1X7U7D7|A0A1X7U7D7_AMPQE 697 RVGDRLKELLAALGISLLSFRSYR-YTNHLWGAYRKLISYPHdlrwrltkappftasippapgaaaalnasggpleeag 774
                                     *********************777.577899*****9988887888888999999999999999999999999999888 PP

                            TruD 387 .......dlelsaeede..ltleFsLpkGsYATvvlrEi 416
                                            d  +  e++   l+leF L++G+Y T+++ Ei
  tr|A0A1X7U7D7|A0A1X7U7D7_AMPQE 775 sggppqsD--VPPEDSMpcLELEFDLDPGTYVTTMMNEI 811
                                     88888443..43433334588899999999999988885 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                        43435  (14716620 residues searched)
Passed MSV filter:                      1565  (0.0360309); expected 868.7 (0.02)
Passed bias filter:                      858  (0.0197537); expected 868.7 (0.02)
Passed Vit filter:                        55  (0.00126626); expected 43.4 (0.001)
Passed Fwd filter:                         2  (4.60458e-05); expected 0.4 (1e-05)
Initial search space (Z):              43435  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.01s 00:00:00.41 Elapsed: 00:00:00.13
# Mc/sec: 47093.18
//
[ok]