# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Anolis_carolinensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    9.4e-74  248.7   0.0    8.7e-69  232.4   0.0    2.4  2  tr|G1KQ00|G1KQ00_ANOCA  Pseudouridylate synthase 7 OS=Anolis 
    2.2e-70  237.6   0.0    5.7e-67  226.4   0.0    2.2  2  tr|G1KBG1|G1KBG1_ANOCA  Pseudouridylate synthase 7 like OS=An
  ------ inclusion threshold ------
       0.35    9.7   2.6       0.49    9.2   0.4    1.9  2  tr|H9GR00|H9GR00_ANOCA  Uncharacterized protein OS=Anolis car


Domain annotation for each sequence (and alignments):
>> tr|G1KQ00|G1KQ00_ANOCA  Pseudouridylate synthase 7 OS=Anolis carolinensis OX=28377 GN=PUS7 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.1   3.1e-06     0.019       2      32 ..     105     135 ..     104     152 .. 0.88
   2 !  232.4   0.0   1.4e-72   8.7e-69      39     416 .]     243     633 ..     231     633 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 3.1e-06
                    TruD   2 lgielyvtdtegigGrlrespeDFiVeEiee 32 
                             +gi  +v+  +g+ G l+e++ DF+V+Ei +
  tr|G1KQ00|G1KQ00_ANOCA 105 VGITKFVSTYKGFSGILKERYSDFVVHEIGK 135
                             899**************************54 PP

  == domain 2  score: 232.4 bits;  conditional E-value: 1.4e-72
                    TruD  39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlG 123
                             +++g+y+ + + k+n dt+d+++ l++ l+++ + ++++GtKDkrA+T+Q i++ ++++++l++l   + + +l ++  ++++l+lG
  tr|G1KQ00|G1KQ00_ANOCA 243 KSRGSYCHFVLYKENKDTMDAINMLSKFLRVKPNIFSYMGTKDKRAITVQEIAVLRITAQRLAHLnkCLMNFKLGNFSYKNHPLKLG 329
                             578***********************************************************9996668****************** PP

                    TruD 124 dLaGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedtrea 210
                             +L+GN+F++++r+++ ++   +++++ +++l+e g + Ny+G+QRFG++   t+ vG+ai++++++e v+ ++     +e+    + 
  tr|G1KQ00|G1KQ00_ANOCA 330 ELQGNHFTVVLRNITGTD---EQVQHAMQSLREIG-FINYYGMQRFGTTAIPTYQVGRAILQNNWNEVVDLILKPRPGAEKGYLVKC 412
                             *************95445...59**********99.***********************************99999999******** PP

                    TruD 211 reavaetgdleealeelpkslryEramlkrLae.kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvi 296
                             re  a+t+d ++al++lp +  +E ++l+ L +   k++ +A+  +p+n + +++h+yqSy++N+++s+R+e++    ++v+GD+v+
  tr|G1KQ00|G1KQ00_ANOCA 413 REEWAKTKDPAAALRKLPVKRCVEGQLLRGLSKyGLKNIVSAFGIIPRNNRLMYIHSYQSYVWNNMVSKRIEEY-G-LKAVPGDLVL 497
                             *********************************66799**********************************99.4.48*******9 PP

                    TruD 297 faeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRaill 383
                             +   +         ++e+++++++         +++pl+G+++  ++ + ge  +e+l+ ++l+ ++ k +k+ + s +G++R++++
  tr|G1KQ00|G1KQ00_ANOCA 498 KGGTA-------TYIEESEADNYT------IHDIVMPLPGFDVIYPKHKIGEAYKEILAADNLDINNMK-HKIRDYSLSGAYRKVII 570
                             99555.......888888888888......44689**********************************.5689************* PP

                    TruD 384 rve..............................dlelsaeedeltleFsLpkGsYATvvlrEi 416
                             r++                               l+++ + + l+++FsLp+ +YAT+ +rE+
  tr|G1KQ00|G1KQ00_ANOCA 571 RPQhvswelvayddpkiplfttdldkmegktpaVLATEGKYKALKMDFSLPPSTYATMAIREV 633
                             **************************99998764445555666******************96 PP

>> tr|G1KBG1|G1KBG1_ANOCA  Pseudouridylate synthase 7 like OS=Anolis carolinensis OX=28377 GN=PUS7L PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.0   0.0   9.3e-05      0.58       5      33 ..      14      42 ..      11      55 .. 0.85
   2 !  226.4   0.0   9.3e-71   5.7e-67      37     416 .]     292     693 ..     277     693 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 9.3e-05
                    TruD  5 elyvtdtegigGrlrespeDFiVeEieef 33
                            ++yv d+ g+ G +++ p DF+V+Ei+  
  tr|G1KBG1|G1KBG1_ANOCA 14 STYVNDHVGFWGCIKTFPSDFVVTEINMH 42
                            68************************543 PP

  == domain 2  score: 226.4 bits;  conditional E-value: 9.3e-71
                    TruD  37 eeakegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeeleklei....kdvelevvgrarrk 119
                             +++ke  y+ ++++k+n +tl++++ l+++lg+  +++++ G+KDk+AvT+Q + ++kv+p++l++l i    k++ l+++++ +++
  tr|G1KBG1|G1KBG1_ANOCA 292 NREKEEIYTAFTLQKENLETLEAISYLSSELGVLPSDFSYTGIKDKKAVTYQAMVVKKVTPKRLKELGIiiggKRLGLSNIHSVNQS 378
                             35677788***********************************************************777888************** PP

                    TruD 120 lrlGdLaGNkFeirvrdv.aeee....eaakraeeileelkekggvPNyfGvQRFGsrrpv.thlvGkaivkgdleeAveayvgkpf 200
                             lrlG+L+GN+F+i+vrd+  +++    ++++r+ e +e++k++g + Ny+G QRFG+ + + t  +G a++++++ +Av+ +++   
  tr|G1KBG1|G1KBG1_ANOCA 379 LRLGQLQGNHFAIIVRDLkLHSNdchgNLKERVYEAMEKVKKNG-FINYYGPQRFGQGQNIhTDQIGLALLNEEMVKAVKLFFTPED 464
                             *****************976666567667788888888888887.************88654889***************9998765 PP

                    TruD 201 eeesedtreareavaetgdleealeelpkslryEramlkrLae...kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlergl 284
                             +  ++ +++a++++ et+d++  l  lp+    Er++l++L +   +++   +   ++p+ ++ ++vhAy S ++N+++s R++ + 
  tr|G1KBG1|G1KBG1_ANOCA 465 S--DDPVNKAKKYFLETEDAKGTLAMLPDFKVRERMLLRALNRyglNHEGCIQGWLSIPHSMRIFYVHAYCSKIWNEAVSYRIKTY- 548
                             4..455679**********************************77777777777889***************************99. PP

                    TruD 285 pldepveGDvvifaeer..lpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpkl 369
                               +++v+GD+v+  e++     +d+++++t+++  +     +    +v++p+ G++++ +  +vge  +e l+++gl++ +F+lp+ 
  tr|G1KBG1|G1KBG1_ANOCA 549 -GTSVVTGDLVFSIEDNesCSPSDKVHVITSEEEMAN----KYTINQVIIPMAGYSVQYPTNKVGEWYHERLARDGLQMGHFRLPA- 629
                             .469*******99888754555556666655433333....334457999***********************************8. PP

                    TruD 370 pelsskGtrRaillrve.................dlelsaeede...ltleFsLpkGsYATvvlrEi 416
                              +l++ G +R+il  ++                  + +++   +   l ++F L++ +YATv l Ei
  tr|G1KBG1|G1KBG1_ANOCA 630 LQLNVPGCYRHILKYPHdlsysflenngkdltpgGDCFQD---SifsLSVSFWLDPSCYATVCLGEI 693
                             99***********999978888888887766554222333...25559**************99885 PP

>> tr|H9GR00|H9GR00_ANOCA  Uncharacterized protein OS=Anolis carolinensis OX=28377 GN=brinp3 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.1     0.048     3e+02     254     271 ..     167     184 ..     147     185 .. 0.84
   2 ?    9.2   0.4   7.9e-05      0.49     204     268 ..     228     292 ..     219     310 .. 0.89

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.048
                    TruD 254 alpknLqrlFvhAyqSyl 271
                              lp+ Lq+ Fv+A+ Sy+
  tr|H9GR00|H9GR00_ANOCA 167 ILPEYLQERFVQAALSYI 184
                             59**************97 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 7.9e-05
                    TruD 204 sedtreareavaetgdleealeelpkslryEramlkrLaekpkdykkAlealpknLqrlFvhAyq 268
                             se++++  + ++++++++  ++++p ++  + + + +L + + ++++  e+l++ +++lF++A +
  tr|H9GR00|H9GR00_ANOCA 228 SETWNTYNNEFEDSDEFKFFMKRMPMNYFLNTSAIMHLWTMDSNFQHRYEQLETSMKQLFLKAQR 292
                             6778888899999*************************************************965 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                        18528  (9796552 residues searched)
Passed MSV filter:                       774  (0.0417746); expected 370.6 (0.02)
Passed bias filter:                      344  (0.0185665); expected 370.6 (0.02)
Passed Vit filter:                        36  (0.00194301); expected 18.5 (0.001)
Passed Fwd filter:                         3  (0.000161917); expected 0.2 (1e-05)
Initial search space (Z):              18528  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.28u 0.01s 00:00:00.29 Elapsed: 00:00:00.09
# Mc/sec: 45281.84
//
[ok]