# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Branchiostoma_floridae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    2.4e-69  234.8   0.0      1e-63  216.3   0.0    3.1  3  tr|C3YAS5|C3YAS5_BRAFL  Uncharacterized protein OS=Branchiost
    1.7e-61  209.0   0.0    2.3e-53  182.2   0.0    3.3  3  tr|C3YUB6|C3YUB6_BRAFL  Uncharacterized protein OS=Branchiost
      2e-34  119.8   0.0    3.3e-34  119.1   0.0    1.4  1  tr|C3Z9T3|C3Z9T3_BRAFL  Uncharacterized protein (Fragment) OS
    9.3e-07   28.7   0.2    0.00082   19.0   0.0    2.4  2  tr|C3Z9T6|C3Z9T6_BRAFL  Uncharacterized protein OS=Branchiost
  ------ inclusion threshold ------
      0.011   15.2   0.9        4.1    6.8   0.0    3.1  3  tr|C3YGK9|C3YGK9_BRAFL  Uncharacterized protein (Fragment) OS
       0.14   11.6   0.7        0.2   11.1   0.7    1.1  1  tr|C3Y4L8|C3Y4L8_BRAFL  Uncharacterized protein OS=Branchiost


Domain annotation for each sequence (and alignments):
>> tr|C3YAS5|C3YAS5_BRAFL  Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_82453 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.2   0.0    0.0025        12       2      32 ..      25      55 ..      24      70 .. 0.87
   2 !  216.3   0.0   2.1e-67     1e-63      44     391 ..     420     770 ..     392     781 .. 0.88
   3 !    9.5   0.0   0.00013       0.6     391     416 .]     834     859 ..     806     859 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0025
                    TruD  2 lgielyvtdtegigGrlrespeDFiVeEiee 32
                             gi ++++++ ++ G+++  peDF V Ei +
  tr|C3YAS5|C3YAS5_BRAFL 25 CGITCHLSSHLPFRGNIKVFPEDFKVIEIDN 55
                            5899999999*******************54 PP

  == domain 2  score: 216.3 bits;  conditional E-value: 2.1e-67
                    TruD  44 ylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl....eikdvelevvgrarrklrlGdLa 126
                             y+ +++ krn +tld++++lar ++ + +++++aG+KDkrAvT Q ++ r+v+p++l+++    +++dv++e++   +++l+lG+La
  tr|C3YAS5|C3YAS5_BRAFL 420 YTGFTLCKRNLETLDVIQRLARCVSAHPSDFSYAGVKDKRAVTWQAMAARGVTPDSLRSAsahpSLRDVQMEKFLLRQQPLHLGNLA 506
                             5778999**************************************************999999999********************* PP

                    TruD 127 GNkFeirvrdv..aeee......eaakraeeileelkekggvPNyfGvQRFGsr..rpvthlvGkaivkgdleeAveayvgkpfeee 203
                             GN F++ +rdv  ++        ++++ + + ++++ke+g + NyfG+QRFGs   ++    vG+a++kgd+++Av++++     + 
  tr|C3YAS5|C3YAS5_BRAFL 507 GNVFKVLLRDVrlCQ-GdtrdrrQLEAVVGAAMDSVKETG-FINYFGLQRFGSAdsKSFAPHVGRALLKGDMSAAVRCLLHPDPAD- 590
                             **********97433.247666666677888899999988.***********9722445557****************99765544. PP

                    TruD 204 sedtreareavaetgdleealeelpkslryEramlkrLaekpkd...ykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpld 287
                              + +++a++++++tgd+   l+++p + + E  +lk+L ++++d     kA+ ++p+ ++ lFvh+y S ++Nr++s+R++ +   +
  tr|C3YAS5|C3YAS5_BRAFL 591 -DPVNAAKAYYMRTGDIPGTLSRMPAHKTRECLLLKALHRHGNDlegCTKAFLNVPHAMRALFVHSYCSLVWNRMVSHRIRTY--GR 674
                             .445699*********************************88885556789999***************************99..57 PP

                    TruD 288 epveGDvvifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelss 374
                             ++veGD+v++++     +++++++t++ v++ +  i+     v++pl+G + + ++ +vge   + l+e+g+e+++F++ +  +l+ 
  tr|C3YAS5|C3YAS5_BRAFL 675 RAVEGDLVLETDAG---NRKVKTLTQTDVDQGNYSIH----DVVLPLLGNSIQYPSNRVGEEYARALQEDGMERSSFRMRA-LKLNI 753
                             ***********888...88999999999999997775....599**********************************997.9**** PP

                    TruD 375 kGtrRaillrvedlels 391
                              G++R++  r++dl+ +
  tr|C3YAS5|C3YAS5_BRAFL 754 PGDYRHVTARPKDLAWE 770
                             **********9987655 PP

  == domain 3  score: 9.5 bits;  conditional E-value: 0.00013
                    TruD 391 saeedeltleFsLpkGsYATvvlrEi 416
                             + ++ ++  +F+L++ +YAT++lrE+
  tr|C3YAS5|C3YAS5_BRAFL 834 HGDSFHVRTRFALDPSCYATMFLREV 859
                             344445899****************6 PP

>> tr|C3YUB6|C3YUB6_BRAFL  Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_79734 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0   4.9e-07    0.0023       2      31 ..      96     125 ..      95     139 .. 0.87
   2 !    5.3   0.0    0.0024        12      43      73 ..     237     267 ..     222     269 .. 0.88
   3 !  182.2   0.0   4.9e-57   2.3e-53     112     416 .]     282     587 ..     270     587 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 4.9e-07
                    TruD   2 lgielyvtdtegigGrlrespeDFiVeEie 31 
                             +gi  y++++eg+ G +++++ DF+V+E+ 
  tr|C3YUB6|C3YUB6_BRAFL  96 VGITEYISKHEGFSGIIKQRYSDFLVREVD 125
                             89**************************93 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0024
                    TruD  43 eylvlrvekrnwdtldlvrelaralgisrkr 73 
                             +y+ + + k+n dt+d+++ la +l+i  +r
  tr|C3YUB6|C3YUB6_BRAFL 237 DYCHFVLYKENLDTMDAINMLAMNLRIAAER 267
                             78999**********************9988 PP

  == domain 3  score: 182.2 bits;  conditional E-value: 4.9e-57
                    TruD 112 vvgrarrklrlGdLaGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgk 198
                             ++  ++++l+lG L GN+F+i++r+++ ++   +++e+ + +l+++g + NyfG+QRFG++   +h vG+a+++ ++eeA+e ++  
  tr|C3YUB6|C3YUB6_BRAFL 282 NFRYTEQPLKLGLLSGNHFTIVLRNCTGSP---EQIEAGMTSLRDNG-FINYFGMQRFGTTSVPSHHVGRALLHSKWEEAIELILKP 364
                             5677899******************85455...59**********98.*********************************977654 PP

                    TruD 199 pf.eeesedtreareavaetgdleealeelpksl...ryEramlkrLaekpkdykkAlealpknLqrlFvhAyqSylFNrvlseRle 281
                                e+++  + + r++ ++t+d++ ale +p++    ++E  +l+ L++++kd  +Al+++p+n + ++vh+yqS+++N+++s+Rl+
  tr|C3YUB6|C3YUB6_BRAFL 365 REgEHQEGAVSACRDFWWKTRDAKGALEMMPRRNmskDIEGRLLEGLVKNGKDLVGALSNIPRNTRLMYVHSYQSFIWNNIVSRRLQ 451
                             3313344467888******************9752224699********************************************** PP

                    TruD 282 rglpldepveGDvvifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpk 368
                             ++    +p+ GD+v++++e+ +++++ +++te+ + +++         v+ pl+G+++  ++ +++e  re+l+ ++l++++ + + 
  tr|C3YUB6|C3YUB6_BRAFL 452 EY--GYQPIVGDLVLEEKEDGAQRSEAKVLTEEDMGNYT------IHDVVFPLFGYDVIYPKHKAEEWYREMLSVDQLDMDNIRHK- 529
                             99..469**********9998899999999988887777......45799********************************9943. PP

                    TruD 369 lpelsskGtrRaillrve..........dlelsaeedeltleFsLpkGsYATvvlrEi 416
                             ++ +    +++  l+ ++           ++ + + + l++eF+Lp+ +YAT+ lrEi
  tr|C3YUB6|C3YUB6_BRAFL 530 VKSVMCYDDVKIPLMLTDkdvldgkeapLASSEGKMKALKVEFTLPPSTYATMALREI 587
                             45555555555444444478999998763344555566*******************7 PP

>> tr|C3Z9T3|C3Z9T3_BRAFL  Uncharacterized protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=Hsd11b1H PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.1   0.0     7e-38   3.3e-34     177     416 .]       1     258 [.       1     258 [. 0.91

  Alignments for each domain:
  == domain 1  score: 119.1 bits;  conditional E-value: 7e-38
                    TruD 177 hlvGkaivkgdleeAveayvgkpfeeesedtreareavaetgdleealeelpksl...ryEramlkrLaekpkdykkAlealpknLq 260
                             h + +a+++ ++eeA+e ++      ++  + + r++ ++t+d++ ale +p++    ++E  +l+ L++++kd  +Al+++p+n +
  tr|C3Z9T3|C3Z9T3_BRAFL   1 HFLHRALLHSKWEEAIELILKPREGGTEGAVSACRDYWWKTRDAKGALEMMPRRNmskDIEGRLLEGLVKNGKDLVGALSNIPRNTR 87 
                             667799***********99999999999999*********************9752224699************************* PP

                    TruD 261 rlFvhAyqSylFNrvlseRlerglpldepveGDvvifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevg 347
                              ++vh+yqS+++N+++s+Rl+++  + +p++GD+v++++e+       +++te+ + +++         v+ pl+G+++  ++ +++
  tr|C3Z9T3|C3Z9T3_BRAFL  88 LMYVHSYQSFIWNNIVSRRLQEY-GF-QPIAGDLVLEEREA-------KVLTEEDLGNYT------IHDVVFPLFGYDVIYPKHKAE 159
                             *********************99.44.8*******999776.......888888888777......45799**************** PP

                    TruD 348 eierevleeegleledFklpklpelsskGtrRaillrve...............................dlelsaeedeltleFsL 403
                             e  re+l+ ++l++++ + +k+++ s +G++R+i+++++                                ++ + + + l++eF+L
  tr|C3Z9T3|C3Z9T3_BRAFL 160 EWYREMLSVDQLDMDNIR-HKVKDYSLSGAYRKIIVKPTnckwqvcykvqscriplmltdkdvldgkeapLASSEGKMKALKVEFTL 245
                             *****************9.5579***************9*************************9998763344555566******* PP

                    TruD 404 pkGsYATvvlrEi 416
                             p+ +YAT+ lrEi
  tr|C3Z9T3|C3Z9T3_BRAFL 246 PPSTYATMALREI 258
                             ************7 PP

>> tr|C3Z9T6|C3Z9T6_BRAFL  Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_81246 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.0   1.7e-07   0.00082       2      33 ..      93     123 ..      92     138 .. 0.86
   2 !    7.5   0.0   0.00052       2.5      41      73 ..     232     264 ..     205     266 .. 0.85

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 1.7e-07
                    TruD   2 lgielyvtdtegigGrlrespeDFiVeEieef 33 
                             +gi  y++++eg+ G +++++ DF+V+E+  +
  tr|C3Z9T6|C3Z9T6_BRAFL  93 VGITEYISKHEGFSGIIKQRYSDFLVREVD-V 123
                             89**************************93.3 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.00052
                    TruD  41 egeylvlrvekrnwdtldlvrelaralgisrkr 73 
                             + +y+ + + k+n dt+d+++ la +l+i  +r
  tr|C3Z9T6|C3Z9T6_BRAFL 232 RPDYCHFVLYKENLDTMDAINMLAMNLRIAAER 264
                             467999***********************9988 PP

>> tr|C3YGK9|C3YGK9_BRAFL  Uncharacterized protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_79351 PE=4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0   0.00086       4.1     154     178 ..     104     127 ..      86     133 .. 0.82
   2 ?    2.4   0.0     0.018        85     154     175 ..     331     351 ..     311     359 .. 0.78
   3 ?    2.4   0.0     0.018        85     154     175 ..     629     649 ..     609     657 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.00086
                    TruD 154 lkekggvPNyfGvQRFGsrrpvthl 178
                             l + g +P  f +QR+G +r +t+ 
  tr|C3YGK9|C3YGK9_BRAFL 104 LPADG-LPDSFEWQRYGYVRYITKA 127
                             45545.****************984 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.018
                    TruD 154 lkekggvPNyfGvQRFGsrrpv 175
                             l + g +P  f +QR+G +r +
  tr|C3YGK9|C3YGK9_BRAFL 331 LPADG-LPCSFEWQRYGYVRYT 351
                             45545.9***********9964 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.018
                    TruD 154 lkekggvPNyfGvQRFGsrrpv 175
                             l + g +P  f +QR+G +r +
  tr|C3YGK9|C3YGK9_BRAFL 629 LPADG-LPCSFEWQRYGYVRYT 649
                             45545.9***********9964 PP

>> tr|C3Y4L8|C3Y4L8_BRAFL  Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_73889 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.7   4.2e-05       0.2     195     310 ..     435     553 ..     432     581 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 4.2e-05
                    TruD 195 yvgkpfeeesedtreareavae..tgdleea.leelpkslryEramlkrLae....kpkdykkAlealpknLqrlFvhAyqSylFNr 274
                             y+  p+++  e+ r+ rea ++  ++d++ a l+++ k +r  +++++ + +    +++++ +A e+++++   +F + +qS++F r
  tr|C3Y4L8|C3Y4L8_BRAFL 435 YLHSPTPTSVEEARKHREAWQQelSRDIQVAfLQTMVKLFRDVKEYVSTVNHrrylNKDKFLAAQEDVDQP---FFREVCQSHMFKR 518
                             88889999999999999998665678988654788889999999999999887777777777777777765...789********** PP

                    TruD 275 vlseRlerglpldepveGDvvifaeerlpdtdrlql 310
                             +l++R++++ ++ +++e+ + ++ ee+ ++  + ++
  tr|C3Y4L8|C3Y4L8_BRAFL 519 FLQDRMDQKRDYYSIMEETMQWQGEEK-AEIPDNKI 553
                             ************999999999998877.33333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                        28542  (13248087 residues searched)
Passed MSV filter:                       958  (0.0335646); expected 570.8 (0.02)
Passed bias filter:                      466  (0.0163268); expected 570.8 (0.02)
Passed Vit filter:                        37  (0.00129634); expected 28.5 (0.001)
Passed Fwd filter:                         6  (0.000210217); expected 0.3 (1e-05)
Initial search space (Z):              28542  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.39u 0.01s 00:00:00.40 Elapsed: 00:00:00.12
# Mc/sec: 45926.70
//
[ok]