# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TruD.hmm.txt
# target sequence database: proteomes/Homo_sapiens.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TruD [M=416]
Accession: PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.4e-73 250.4 0.0 1.9e-69 236.8 0.0 2.2 2 sp|Q9H0K6|PUS7L_HUMAN Pseudouridylate synthase 7 homolog-l
3.7e-73 249.0 0.0 9.6e-68 231.2 0.0 2.3 2 sp|Q96PZ0|PUS7_HUMAN Pseudouridylate synthase 7 homolog O
1.1e-66 227.7 0.0 1.3e-66 227.4 0.0 1.1 1 tr|B3KUJ1|B3KUJ1_HUMAN Pseudouridylate synthase 7 homolog-l
2.3e-45 157.5 0.1 8.2e-40 139.2 0.0 2.2 2 tr|E7EUH7|E7EUH7_HUMAN Pseudouridylate synthase 7 homolog O
1.5e-32 115.3 0.3 1.6e-32 115.1 0.3 1.0 1 tr|F8VW99|F8VW99_HUMAN Pseudouridylate synthase 7 homolog-l
2e-32 114.8 0.5 2.2e-32 114.7 0.5 1.0 1 tr|F8VP66|F8VP66_HUMAN Pseudouridylate synthase 7 homolog-l
1.5e-14 56.0 0.0 4.6e-10 41.2 0.0 2.2 2 tr|F8VZA0|F8VZA0_HUMAN Pseudouridylate synthase 7 homolog-l
0.00039 21.6 0.0 0.12 13.4 0.0 2.1 2 tr|H0Y863|H0Y863_HUMAN Pseudouridylate synthase 7 homolog (
------ inclusion threshold ------
0.025 15.7 0.0 0.032 15.3 0.0 1.1 1 tr|F8VWC0|F8VWC0_HUMAN Pseudouridylate synthase 7 homolog-l
1.2 10.2 0.0 1.2 10.2 0.0 1.0 1 tr|M0R0M6|M0R0M6_HUMAN Zinc finger protein 417 (Fragment) O
2.2 9.3 3.9 17 6.4 0.4 2.3 2 sp|Q6ZMZ3-3|SYNE3_HUMAN Isoform 3 of Nesprin-3 OS=Homo sapie
Domain annotation for each sequence (and alignments):
>> sp|Q9H0K6|PUS7L_HUMAN Pseudouridylate synthase 7 homolog-like protein OS=Homo sapiens GN=PUS7L PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 11.5 0.0 5.6e-05 0.45 6 35 .. 15 43 .. 11 70 .. 0.73
2 ! 236.8 0.0 2.4e-73 1.9e-69 39 416 .] 295 696 .. 279 696 .. 0.86
Alignments for each domain:
== domain 1 score: 11.5 bits; conditional E-value: 5.6e-05
TruD 6 lyvtdtegigGrlrespeDFiVeEieefsg 35
+++ d+ g+ G++++sp DFiV Ei e g
sp|Q9H0K6|PUS7L_HUMAN 15 CFFNDHVGFHGTIKSSPSDFIVIEIDEQ-G 43
6778999******************655.2 PP
== domain 2 score: 236.8 bits; conditional E-value: 2.4e-73
TruD 39 akegey..lvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..ei..kdvelevvgrarrkl 120
+eg++ + ++++k+n ++ +++ la +lg+ +++++aG+KDk+A+T+Q + +rkv+pe+l+++ ei k++++ ++ + + +l
sp|Q9H0K6|PUS7L_HUMAN 295 CQEGKViyTAFTLRKENLEMFEAIGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIekEIekKRMNVFNIRSVDDSL 382
455665448899*****************************************************9988444488999999******* PP
TruD 121 rlGdLaGNkFeirvrdv.aeee...eaakraeeileelkekggvPNyfGvQRFGsrrpv.thlvGkaivkgdleeAveayvgkpfeee 203
rlG+L+GN+F+i++r++ ++ + ++++r+ e +e++k+kg + Ny+G QRFG+ r v t +G a++k+++ +A++ +++
sp|Q9H0K6|PUS7L_HUMAN 383 RLGQLKGNHFDIVIRNLkKQINdsaNLRERIMEAIENVKKKG-FVNYYGPQRFGKGRKVhTDQIGLALLKNEMMKAIKLFLTPED--L 467
****************85544444455566666666777766.************8875489******************98765..4 PP
TruD 204 sedtreareavaetgdleealeelpkslryEramlkrLae...kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglplde 288
++ +++a++++ +t+d++ l+++p+ Era+l++L + +++ +A +lp+ ++ ++vhAy S ++N+++s Rle + +
sp|Q9H0K6|PUS7L_HUMAN 468 DDPVNRAKKYFLQTEDAKGTLSLMPEFKVRERALLEALHRfgmTEEGCIQAWFSLPHSMRIFYVHAYTSKIWNEAVSYRLETY--GAR 553
5556799*********************************88888889999999***************************99..57* PP
TruD 289 pveGDvvifaeer...lpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpels 373
+v+GD+v+ +e+ + +++++lvte++ + +v++p++G++ + ++ +vg+ +++l+++gl++ Fk+p+ +l+
sp|Q9H0K6|PUS7L_HUMAN 554 VVQGDLVCLDEDIddeNFPNSKIHLVTEEEGSANMYA----IHQVVLPVLGYNIQYPKNKVGQWYHDILSRDGLQTCRFKVPT-LKLN 636
*********9877666666777888877665544433....34799************************************8.9*** PP
TruD 374 skGtrRaillrve.................dlelsaeedeltleFsLpkGsYATvvlrEi 416
G +R+il ++ +++++ +l+++F L+ +YATv l+Ei
sp|Q9H0K6|PUS7L_HUMAN 637 IPGCYRQILKHPCnlsyqlmedhdidvktkGSHIDETALSLLISFDLDASCYATVCLKEI 696
********9988889999***99887765544455555569*****************97 PP
>> sp|Q96PZ0|PUS7_HUMAN Pseudouridylate synthase 7 homolog OS=Homo sapiens GN=PUS7 PE=1 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.6 0.0 3.3e-06 0.027 2 32 .. 114 144 .. 113 194 .. 0.87
2 ! 231.2 0.0 1.2e-71 9.6e-68 39 416 .] 252 642 .. 240 642 .. 0.93
Alignments for each domain:
== domain 1 score: 15.6 bits; conditional E-value: 3.3e-06
TruD 2 lgielyvtdtegigGrlrespeDFiVeEiee 32
+gi +v++++g+ G l+e++ DF+V+Ei +
sp|Q96PZ0|PUS7_HUMAN 114 VGITKFVSSHQGFSGILKERYSDFVVHEIGK 144
89***************************54 PP
== domain 2 score: 231.2 bits; conditional E-value: 1.2e-71
TruD 39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlGdL 125
+++g+y+ + + k+n dt+d+++ l++ l+++ + ++++GtKDkrA+T+Q i++ k+++++l++l + + +l ++ ++++l+lG+L
sp|Q96PZ0|PUS7_HUMAN 252 KSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITVQEIAVLKITAQRLAHLnkCLMNFKLGNFSYQKNPLKLGEL 340
578***********************************************************9996668******************** PP
TruD 126 aGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedtreareav 214
+GN+F++++r+++ ++ +++++ +++lke g + Ny+G+QRFG++ t+ vG+ai+++ + e ++ ++ + +e+ + re
sp|Q96PZ0|PUS7_HUMAN 341 QGNHFTVVLRNITGTD---DQVQQAMNSLKEIG-FINYYGMQRFGTTAVPTYQVGRAILQNSWTEVMDLILKPRSGAEKGYLVKCREEW 425
***********95444...59**********99.*******************************99999999999************* PP
TruD 215 aetgdleealeelpkslryEramlkrLae.kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvifaeerl 302
a+t+d ++al++lp + +E ++l+ L + k++ +A+ +p+n + +++h+yqSy++N+++s+R+e++ +pv+GD+v++ +
sp|Q96PZ0|PUS7_HUMAN 426 AKTKDPTAALRKLPVKRCVEGQLLRGLSKyGMKNIVSAFGIIPRNNRLMYIHSYQSYVWNNMVSKRIEDY-G-LKPVPGDLVLKGATA- 511
*****************************77899**********************************99.4.48*******999554. PP
TruD 303 pdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRaillrve..... 386
++e+ v++++ v++pl+G+++ ++ + +e re+l ++l+ ++ + +k+ + s +G++R+i++r++
sp|Q96PZ0|PUS7_HUMAN 512 ------TYIEEDDVNNYS------IHDVVMPLPGFDVIYPKHKIQEAYREMLTADNLDIDNMR-HKIRDYSLSGAYRKIIIRPQnvswe 587
......667776666666......45799*********************************9.5689********************* PP
TruD 387 .........................dlelsaeedeltleFsLpkGsYATvvlrEi 416
++ + + + l+++FsLp+ +YAT+ +rE+
sp|Q96PZ0|PUS7_HUMAN 588 vvayddpkiplfntdvdnlegktppVFASEGKYRALKMDFSLPPSTYATMAIREV 642
*******************9999875666666777******************96 PP
>> tr|B3KUJ1|B3KUJ1_HUMAN Pseudouridylate synthase 7 homolog-like protein OS=Homo sapiens GN=PUS7L PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 227.4 0.0 1.6e-70 1.3e-66 59 416 .] 4 383 .. 1 383 [. 0.87
Alignments for each domain:
== domain 1 score: 227.4 bits; conditional E-value: 1.6e-70
TruD 59 lvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..ei..kdvelevvgrarrklrlGdLaGNkFeirvrdv.aee 140
++ la +lg+ +++++aG+KDk+A+T+Q + +rkv+pe+l+++ ei k++++ ++ + + +lrlG+L+GN+F+i++r++ ++
tr|B3KUJ1|B3KUJ1_HUMAN 4 AIGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIekEIekKRMNVFNIRSVDDSLRLGQLKGNHFDIVIRNLkKQI 90
67779999***********************************9988444488999999***********************85544 PP
TruD 141 e...eaakraeeileelkekggvPNyfGvQRFGsrrpv.thlvGkaivkgdleeAveayvgkpfeeesedtreareavaetgdleea 223
+ ++++r+ e +e++k+kg + Ny+G QRFG+ r v t +G a++k+++ +A++ +++ ++ +++a++++ +t+d++
tr|B3KUJ1|B3KUJ1_HUMAN 91 NdsaNLRERIMEAIENVKKKG-FVNYYGPQRFGKGRKVhTDQIGLALLKNEMMKAIKLFLTPED--LDDPVNRAKKYFLQTEDAKGT 174
444455566666666777766.************8875489******************98765..45556799************* PP
TruD 224 leelpkslryEramlkrLae...kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvifaeer...lpd 304
l+++p+ Era+l++L + +++ +A +lp+ ++ ++vhAy S ++N+++s Rle + ++v+GD+v+ +e+ +
tr|B3KUJ1|B3KUJ1_HUMAN 175 LSLMPEFKVRERALLEALHRfgmTEEGCIQAWFSLPHSMRIFYVHAYTSKIWNEAVSYRLETY--GARVVQGDLVCLDEDIddeNFP 259
********************88888889999999***************************99..57**********9877666666 PP
TruD 305 tdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRaillrve..... 386
+++++lvte++ + +v++p++G++ + ++ +vg+ +++l+++gl++ Fk+p+ +l+ G +R+il ++
tr|B3KUJ1|B3KUJ1_HUMAN 260 NSKIHLVTEEEGSANMYA----IHQVVLPVLGYNIQYPKNKVGQWYHDILSRDGLQTCRFKVPT-LKLNIPGCYRQILKHPCnlsyq 341
777888877665544433....34799************************************8.9***********9988889999 PP
TruD 387 ............dlelsaeedeltleFsLpkGsYATvvlrEi 416
+++++ +l+++F L+ +YATv l+Ei
tr|B3KUJ1|B3KUJ1_HUMAN 342 lmedhdidvktkGSHIDETALSLLISFDLDASCYATVCLKEI 383
***99887765544455555569*****************97 PP
>> tr|E7EUH7|E7EUH7_HUMAN Pseudouridylate synthase 7 homolog OS=Homo sapiens GN=PUS7 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.3 0.0 2e-06 0.016 2 33 .. 114 145 .. 113 196 .. 0.87
2 ! 139.2 0.0 1e-43 8.2e-40 39 230 .. 252 441 .. 240 445 .. 0.94
Alignments for each domain:
== domain 1 score: 16.3 bits; conditional E-value: 2e-06
TruD 2 lgielyvtdtegigGrlrespeDFiVeEieef 33
+gi +v++++g+ G l+e++ DF+V+Ei +
tr|E7EUH7|E7EUH7_HUMAN 114 VGITKFVSSHQGFSGILKERYSDFVVHEIGKD 145
89***************************554 PP
== domain 2 score: 139.2 bits; conditional E-value: 1e-43
TruD 39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlG 123
+++g+y+ + + k+n dt+d+++ l++ l+++ + ++++GtKDkrA+T+Q i++ k+++++l++l + + +l ++ ++++l+lG
tr|E7EUH7|E7EUH7_HUMAN 252 KSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITVQEIAVLKITAQRLAHLnkCLMNFKLGNFSYQKNPLKLG 338
578***********************************************************9996668****************** PP
TruD 124 dLaGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedtrea 210
+L+GN+F++++r+++ ++ +++++ +++lke g + Ny+G+QRFG++ t+ vG+ai+++ + e ++ ++ + +e+ +
tr|E7EUH7|E7EUH7_HUMAN 339 ELQGNHFTVVLRNITGTD---DQVQQAMNSLKEIG-FINYYGMQRFGTTAVPTYQVGRAILQNSWTEVMDLILKPRSGAEKGYLVKC 421
*************95444...59**********99.*******************************99999999999********* PP
TruD 211 reavaetgdleealeelpks 230
re a+t+d ++al++lp +
tr|E7EUH7|E7EUH7_HUMAN 422 REEWAKTKDPTAALRKLPVK 441
*****************976 PP
>> tr|F8VW99|F8VW99_HUMAN Pseudouridylate synthase 7 homolog-like protein (Fragment) OS=Homo sapiens GN=PUS7L PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 115.1 0.3 2e-36 1.6e-32 59 197 .. 4 150 .. 1 159 [. 0.85
Alignments for each domain:
== domain 1 score: 115.1 bits; conditional E-value: 2e-36
TruD 59 lvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..ei..kdvelevvgrarrklrlGdLaGNkFeirvrdv.aee 140
++ la +lg+ +++++aG+KDk+A+T+Q + +rkv+pe+l+++ ei k++++ ++ + + +lrlG+L+GN+F+i++r++ ++
tr|F8VW99|F8VW99_HUMAN 4 AIGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIekEIekKRMNVFNIRSVDDSLRLGQLKGNHFDIVIRNLkKQI 90
67789999***********************************9988444488999999***********************85544 PP
TruD 141 e...eaakraeeileelkekggvPNyfGvQRFGsrrpv.thlvGkaivkgdleeAveayvg 197
+ ++++r+ e +e++k+kg + Ny+G QRFG+ r v t +G a++k+++ +A++ +++
tr|F8VW99|F8VW99_HUMAN 91 NdsaNLRERIMEAIENVKKKG-FVNYYGPQRFGKGRKVhTDQIGLALLKNEMMKAIKLFLT 150
444455566666666777766.************8875489****************9986 PP
>> tr|F8VP66|F8VP66_HUMAN Pseudouridylate synthase 7 homolog-like protein (Fragment) OS=Homo sapiens GN=PUS7L PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 114.7 0.5 2.7e-36 2.2e-32 59 197 .. 4 150 .. 1 153 [. 0.86
Alignments for each domain:
== domain 1 score: 114.7 bits; conditional E-value: 2.7e-36
TruD 59 lvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..ei..kdvelevvgrarrklrlGdLaGNkFeirvrdv.aee 140
++ la +lg+ +++++aG+KDk+A+T+Q + +rkv+pe+l+++ ei k++++ ++ + + +lrlG+L+GN+F+i++r++ ++
tr|F8VP66|F8VP66_HUMAN 4 AIGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIekEIekKRMNVFNIRSVDDSLRLGQLKGNHFDIVIRNLkKQI 90
67789999***********************************9988444488999999***********************85544 PP
TruD 141 e...eaakraeeileelkekggvPNyfGvQRFGsrrpv.thlvGkaivkgdleeAveayvg 197
+ ++++r+ e +e++k+kg + Ny+G QRFG+ r v t +G a++k+++ +A++ +++
tr|F8VP66|F8VP66_HUMAN 91 NdsaNLRERIMEAIENVKKKG-FVNYYGPQRFGKGRKVhTDQIGLALLKNEMMKAIKLFLT 150
444455566666666777766.************8875489***************99886 PP
>> tr|F8VZA0|F8VZA0_HUMAN Pseudouridylate synthase 7 homolog-like protein OS=Homo sapiens GN=PUS7L PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 12.8 0.0 2.4e-05 0.19 6 35 .. 15 43 .. 11 70 .. 0.73
2 ! 41.2 0.0 5.7e-14 4.6e-10 39 104 .. 295 362 .. 279 365 .] 0.88
Alignments for each domain:
== domain 1 score: 12.8 bits; conditional E-value: 2.4e-05
TruD 6 lyvtdtegigGrlrespeDFiVeEieefsg 35
+++ d+ g+ G++++sp DFiV Ei e g
tr|F8VZA0|F8VZA0_HUMAN 15 CFFNDHVGFHGTIKSSPSDFIVIEIDEQ-G 43
6788999******************655.2 PP
== domain 2 score: 41.2 bits; conditional E-value: 5.7e-14
TruD 39 akegey..lvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekle 104
+eg++ + ++++k+n ++ +++ la +lg+ +++++aG+KDk+A+T+Q + +rkv+pe+l+++e
tr|F8VZA0|F8VZA0_HUMAN 295 CQEGKViyTAFTLRKENLEMFEAIGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIE 362
456665448899***************************************************99874 PP
>> tr|H0Y863|H0Y863_HUMAN Pseudouridylate synthase 7 homolog (Fragment) OS=Homo sapiens GN=PUS7 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 6.8 0.0 0.0016 13 16 33 .. 3 20 .. 1 65 [. 0.82
2 ! 13.4 0.0 1.5e-05 0.12 39 78 .. 93 132 .] 80 132 .] 0.89
Alignments for each domain:
== domain 1 score: 6.8 bits; conditional E-value: 0.0016
TruD 16 GrlrespeDFiVeEieef 33
G l+e++ DF+V+Ei +
tr|H0Y863|H0Y863_HUMAN 3 GILKERYSDFVVHEIGKD 20
89*************544 PP
== domain 2 score: 13.4 bits; conditional E-value: 1.5e-05
TruD 39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaG 78
+++g+y+ + + k+n dt+d+++ l++ l+++ + ++++G
tr|H0Y863|H0Y863_HUMAN 93 KSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMG 132
678*****************************99999988 PP
>> tr|F8VWC0|F8VWC0_HUMAN Pseudouridylate synthase 7 homolog-like protein (Fragment) OS=Homo sapiens GN=PUS7L PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 15.3 0.0 4e-06 0.032 6 36 .. 15 44 .. 11 70 .. 0.71
Alignments for each domain:
== domain 1 score: 15.3 bits; conditional E-value: 4e-06
TruD 6 lyvtdtegigGrlrespeDFiVeEieefsge 36
+++ d+ g+ G++++sp DFiV Ei e g+
tr|F8VWC0|F8VWC0_HUMAN 15 CFFNDHVGFHGTIKSSPSDFIVIEIDEQ-GQ 44
6788999******************655.22 PP
>> tr|M0R0M6|M0R0M6_HUMAN Zinc finger protein 417 (Fragment) OS=Homo sapiens GN=ZNF417 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.2 0.0 0.00014 1.2 76 102 .. 14 40 .. 5 49 .. 0.85
Alignments for each domain:
== domain 1 score: 10.2 bits; conditional E-value: 0.00014
TruD 76 faGtKDkrAvTtQlisirkvepeelek 102
++G KD +A +Q is+++ ++++ ++
tr|M0R0M6|M0R0M6_HUMAN 14 WCGSKDEEAPCKQRISVQRESQSRTPR 40
9****************8877766665 PP
>> sp|Q6ZMZ3-3|SYNE3_HUMAN Isoform 3 of Nesprin-3 OS=Homo sapiens GN=SYNE3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 6.4 0.4 0.0021 17 179 244 .. 293 360 .. 281 398 .. 0.76
2 ? 3.8 0.2 0.012 99 225 264 .. 530 569 .. 512 573 .. 0.86
Alignments for each domain:
== domain 1 score: 6.4 bits; conditional E-value: 0.0021
TruD 179 vGkaivkgdleeAveayvgkpfeeesedtreareavaetgdleealeelpkslryEramlkrLae...k 244
+G + + g+lee ++ + k +e+ ++ r ++ +g +e+ +++l +l+ r++l+rLa+ +
sp|Q6ZMZ3-3|SYNE3_HUMAN 293 LGAEKITGELEEM-RKVLEKLRALWEEEEERLRGLLRSRGAWEQQIKQLEAELSEFRMVLQRLAQeglQ 360
5666666777664.444445555556666889********************************94431 PP
== domain 2 score: 3.8 bits; conditional E-value: 0.012
TruD 225 eelpkslryEramlkrLaekpkdykkAlealpknLqrlFv 264
++l++sl ++ l++L ++kd+ +A+e l+++L +l v
sp|Q6ZMZ3-3|SYNE3_HUMAN 530 DLLHNSLLQRKSKLQSLLAQHKDFGAAFEPLQRKLLDLQV 569
6788999999999**********************99866 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (416 nodes)
Target sequences: 88473 (35070517 residues searched)
Passed MSV filter: 2972 (0.0335922); expected 1769.5 (0.02)
Passed bias filter: 1504 (0.0169995); expected 1769.5 (0.02)
Passed Vit filter: 150 (0.00169543); expected 88.5 (0.001)
Passed Fwd filter: 14 (0.00015824); expected 0.9 (1e-05)
Initial search space (Z): 88473 [actual number of targets]
Domain search space (domZ): 11 [number of targets reported over threshold]
# CPU time: 1.00u 0.03s 00:00:01.03 Elapsed: 00:00:00.30
# Mc/sec: 48631.12
//
[ok]