# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TruD.hmm.txt
# target sequence database: proteomes/Mus_musculus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TruD [M=416]
Accession: PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.1e-73 248.7 0.0 1.4e-68 232.0 0.0 2.2 2 sp|Q8CE46|PUS7L_MOUSE Pseudouridylate synthase 7 homolog-lik
4.5e-73 246.8 0.0 4.4e-68 230.3 0.0 2.3 2 sp|Q91VU7|PUS7_MOUSE Pseudouridylate synthase 7 homolog OS=
Domain annotation for each sequence (and alignments):
>> sp|Q8CE46|PUS7L_MOUSE Pseudouridylate synthase 7 homolog-like protein OS=Mus musculus OX=10090 GN=Pus7l PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.7 0.0 1.1e-06 0.013 3 43 .. 12 53 .. 10 70 .. 0.73
2 ! 232.0 0.0 1.2e-72 1.4e-68 40 416 .] 298 697 .. 280 697 .. 0.89
Alignments for each domain:
== domain 1 score: 14.7 bits; conditional E-value: 1.1e-06
TruD 3 gielyvtdtegigGrlrespeDFiVeEieefsge.eeakege 43
+ +++ d+ g++G++++sp DFiV Ei e + ++a++g+
sp|Q8CE46|PUS7L_MOUSE 12 NSLCFINDHVGFQGSIKTSPSDFIVIEIDEQGQLvSKATDGS 53
5668999*********************77633224555554 PP
== domain 2 score: 232.0 bits; conditional E-value: 1.2e-72
TruD 40 kegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl....eikdvelevvgrarrklrlG 123
+ y+ ++++k+n +t +++ la +lg+ +++++aG+KDkrA+T+Q + ++kv+pe+l+++ e k++++ ++ + + lrlG
sp|Q8CE46|PUS7L_MOUSE 298 GKAVYTAFTLQKENLETFEAIGLLAVKLGVIPSDFSYAGLKDKRAITYQSMVVKKVTPERLKSIkeeiEKKRMNVFNIRSVGDCLRLG 385
34557999*****************************************************999884444889999999********* PP
TruD 124 dLaGNkFeirvrdv.aeeeeaakraeeileelkekg..gvPNyfGvQRFGsrrpv.thlvGkaivkgdleeAveayvgkpfeeesedt 207
+L+GN+Fei++r + + ++ a+ +e+ile++++ + g+ Ny+G QRFG+ + + t +G a++k+++ +A++ +++ ++ +
sp|Q8CE46|PUS7L_MOUSE 386 QLKGNHFEIIIRHLrNQLNDSANLTERILEAIENVKnkGFVNYYGPQRFGKGQKIqTDQIGLALLKNEMVKAIKLFLTPEDV--DDPV 471
*************98777777777777777777644447***********97654399******************987654..5556 PP
TruD 208 reareavaetgdleealeelpkslryEramlkrLae...kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveG 292
++a++++ +t+d++ l+++p+ Era+l++L + +++ +A ++p+ ++ +++hAy S ++N++ s Rl+++ p ++veG
sp|Q8CE46|PUS7L_MOUSE 472 NKAKQYFLRTEDAKGTLSLMPEFRVRERALLESLHRfgvTEEGCVRAWFSFPHSMRIFYIHAYSSRIWNEAASYRLAAYGP--KVVEG 557
79**********************************999999999*********************************987..9**** PP
TruD 293 Dvvifaeer..lpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtr 378
D+++ +e++ +++++lvt+++ + + +v++p++G++++ +e +vg+ +e l+++gl++ F++p+ +l++ G +
sp|Q8CE46|PUS7L_MOUSE 558 DLICSDEDAdkHFPSSKVHLVTKEEESAHT----YALHQVVLPVLGYNVQYPENQVGRWYQEALSRDGLQACRFRVPA-LKLNVPGCY 640
******998666667778888877666655....4456799************************************8.9******** PP
TruD 379 Raillrve...................dlelsaeedeltleFsLpkGsYATvvlrEi 416
R+i+ +++ + +++ ++l l+F L+ +YATv lrE+
sp|Q8CE46|PUS7L_MOUSE 641 RHIVKHPRnvshrlvhpdpateearveGPHSDDTASSLSLSFDLDASCYATVCLREM 697
****99999************9998885566778888******************96 PP
>> sp|Q91VU7|PUS7_MOUSE Pseudouridylate synthase 7 homolog OS=Mus musculus OX=10090 GN=Pus7 PE=2 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.2 0.0 1.6e-06 0.018 2 32 .. 113 143 .. 112 196 .. 0.88
2 ! 230.3 0.0 3.9e-72 4.4e-68 39 416 .] 251 641 .. 239 641 .. 0.94
Alignments for each domain:
== domain 1 score: 14.2 bits; conditional E-value: 1.6e-06
TruD 2 lgielyvtdtegigGrlrespeDFiVeEiee 32
+gi +v++++g+ G l+e++ DF+V+Ei +
sp|Q91VU7|PUS7_MOUSE 113 VGICKFVSSHHGFSGILKERYSDFVVHEIGK 143
8999*************************54 PP
== domain 2 score: 230.3 bits; conditional E-value: 3.9e-72
TruD 39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlGdL 125
+++g+y+ + + k+n dt+d+++ l++ l+++ + ++++GtKDkrA+T+Q i++ k+++++l++l + +++l ++ ++ +l+lG L
sp|Q91VU7|PUS7_MOUSE 251 KSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITVQEIAVLKISAQRLAHLnkCLMNLKLGNFSYQKTPLKLGAL 339
578***********************************************************9996668******************** PP
TruD 126 aGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedtreareav 214
+GN+F++++r+++ ++ +++++ +++l+e+g + Ny+G+QRFG++ t+ vG+ai+++ + e ++ ++ + +e+ + re
sp|Q91VU7|PUS7_MOUSE 340 QGNHFTVVLRNITGTD---EQVQQAMQSLRETG-FINYYGMQRFGTTAVPTYQVGRAILQNSWTEVMDLILKPRSGAEKGYLVKCREEW 424
***********95444...59**********99.*******************************99999999999************* PP
TruD 215 aetgdleealeelpkslryEramlkrLae.kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvifaeerl 302
a+t+d ++al++lp + +E ++l+ L + k++ +A+ +p+n + +++h+yqSy++N+++s+R+e++ +pv+GD+v++
sp|Q91VU7|PUS7_MOUSE 425 AKTKDPASALKKLPVKRCVEGQLLRGLSRyGMKNIVSAFGIIPRNNRLMYIHSYQSYVWNTMVSRRIEEY-G-LRPVPGDLVLKGATP- 510
****************************977899**********************************99.3.59*******999666. PP
TruD 303 pdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRaillrve..... 386
++e+ v++++ v++pl+G+++ ++ + +e re+l+ ++l+ ++ + ++ + s +G++R+i++r++
sp|Q91VU7|PUS7_MOUSE 511 ------TYIEEDDVDNYS------IHDVVMPLPGFDVIYPKHKISEAYREMLAADNLDIDNMRH-TIRDYSLSGAYRRIIIRPQsvswe 586
......789999999888......45799*********************************94.578********************* PP
TruD 387 .........................dlelsaeedeltleFsLpkGsYATvvlrEi 416
++ + + + l+++FsLp+ +YAT+ +rE+
sp|Q91VU7|PUS7_MOUSE 587 vvayddpkiplfntdvdnlegkpppVFASEGKYRALKMDFSLPPSTYATMAIREV 641
*******************9999986666667777******************96 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (416 nodes)
Target sequences: 22289 (11757923 residues searched)
Passed MSV filter: 809 (0.0362959); expected 445.8 (0.02)
Passed bias filter: 383 (0.0171834); expected 445.8 (0.02)
Passed Vit filter: 39 (0.00174974); expected 22.3 (0.001)
Passed Fwd filter: 2 (8.97304e-05); expected 0.2 (1e-05)
Initial search space (Z): 22289 [actual number of targets]
Domain search space (domZ): 2 [number of targets reported over threshold]
# CPU time: 0.32u 0.02s 00:00:00.34 Elapsed: 00:00:00.14
# Mc/sec: 34937.83
//
[ok]