# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Nematostella_vectensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    4.2e-72  243.7   0.0    6.4e-68  229.9   0.0    2.3  2  tr|A7T011|A7T011_NEMVE  Predicted protein (Fragment) OS=Nemat
    1.7e-18   67.1   0.0      2e-18   66.9   0.0    1.0  1  tr|A7SX02|A7SX02_NEMVE  Predicted protein (Fragment) OS=Nemat
    8.4e-06   25.3   0.1    0.00015   21.2   0.0    2.3  2  tr|A7SWX0|A7SWX0_NEMVE  Predicted protein (Fragment) OS=Nemat
  ------ inclusion threshold ------
      0.036   13.3   0.0      0.055   12.7   0.0    1.2  1  tr|A7SSD7|A7SSD7_NEMVE  Predicted protein OS=Nematostella vec


Domain annotation for each sequence (and alignments):
>> tr|A7T011|A7T011_NEMVE  Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g139787 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.0   1.9e-05      0.11       2      31 ..       4      33 ..       3      76 .. 0.89
   2 !  229.9   0.0     1e-71   6.4e-68      43     416 .]     143     531 ..     129     531 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 1.9e-05
                    TruD  2 lgielyvtdtegigGrlrespeDFiVeEie 31
                            +gi  +++++eg++G l++++ DFiV E +
  tr|A7T011|A7T011_NEMVE  4 VGITEFIAKHEGFQGVLKQRYVDFIVYERN 33
                            8999***********************984 PP

  == domain 2  score: 229.9 bits;  conditional E-value: 1e-71
                    TruD  43 eylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlGdLaG 127
                             +++ + + k+n dt+++++ la+ l+++   +g+aGtKD+r+vT+Q +s +kv +e+l+ l  ++++++l ++   ++klrlGdL G
  tr|A7T011|A7T011_NEMVE 143 DHCKFVLFKENKDTMEAISLLAKLLHVKPGVFGYAGTKDRRGVTVQEVSGYKVLAERLQGLnnTLRGLRLGNFEYCKEKLRLGDLSG 229
                             56778899***************************************************998899********************** PP

                    TruD 128 NkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedtreareav 214
                             N+F i++r+v+    +++ +e+ + +lk+ g + NyfG+QRFG+    th +G+a++  +++eAv+ ++ +p e +++d ++a e+ 
  tr|A7T011|A7T011_NEMVE 230 NHFVITLRNVS---GNCEVIERAMTSLKDVG-FINYFGLQRFGTSCVPTHHIGRALILSQWSEAVD-LILNPREGKPKDFNKALEYW 311
                             *********83...45779**********98.*********************************8.5779**************** PP

                    TruD 215 aetgdleealeelpkslryEramlkrLae.kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvifaee 300
                             + tgd++ al++l ++  +E  +l+  ++  ++d  +Al+ +p+n + ++vhAyqSy++N+++s+R++++     pveGD+v+  + 
  tr|A7T011|A7T011_NEMVE 312 KSTGDAKGALSRLARKKCIESYLLQGFVNqGSQDLVGALQMIPRNTRLMYVHAYQSYIWNNMVSHRIREYG--LVPVEGDLVVSGHT 396
                             **************************99946789**********************************994..47*******99966 PP

                    TruD 301 rlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRaillrve. 386
                             +         v++ + ++++   +     v++p++G++++ +  +v++  re+++ +g++ ++ + +++++ s +G++R+i+++++ 
  tr|A7T011|A7T011_NEMVE 397 Q---------VRTLSHDDIS-SQKYSIHDVVMPVPGYDVTYPGKDVRDWYRELMAVDGVDIDKMR-HRVKDYSLSGAYRPIIIKPQh 472
                             5.........5555555555.2334455799*********************************9.4578***************** PP

                    TruD 387 ...........................dlelsaeede....ltleFsLpkGsYATvvlrEi 416
                                                        d  + ae+d+    l++e +Lp+ +YAT+ lrE+
  tr|A7T011|A7T011_NEMVE 473 tswkfihyndvtaplaltdldrlegrtD--IPAETDGqylaLQIELTLPSSCYATMALREV 531
                             ***********************99653..444444445669999***************6 PP

>> tr|A7SX02|A7SX02_NEMVE  Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g136095 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.9   0.0   3.2e-22     2e-18     213     382 ..       2     172 ..       1     178 [. 0.85

  Alignments for each domain:
  == domain 1  score: 66.9 bits;  conditional E-value: 3.2e-22
                    TruD 213 avaetgdleealeelpkslryEramlkrLaekpkd...ykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvi 296
                             +++etgd+   l ++p   + Er +lk+L ++++d     +Al +lp   + l+ h+y S ++N++ s+R++ +   +++ +GD+v+
  tr|A7SX02|A7SX02_NEMVE   2 YYEETGDIPGTLARMPPGQTRERLILKALHRHGRDkygCTQALLSLPYSARLLYAHSYTSLAWNHAASARVRLYG-STRVAAGDLVY 87 
                             6899***************************7777555899*******************************995.59********* PP

                    TruD 297 faeer...lp.dtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrR 379
                             +++++   +p d+ ++ +v+e+ +       +   a v++pl+G+++  +e +  +  +  l+++ l++edF+l k  +ls  G++R
  tr|A7SX02|A7SX02_NEMVE  88 DSQSAssqTPiDKCAVRVVSEDDAG----SGKYSMADVVLPLPGYSVIYPENKIADSYQGTLNSDRLRAEDFRLRK-LGLSLPGAYR 169
                             **88865322022222223332222....34677899*************************************99.9********* PP

                    TruD 380 ail 382
                             +++
  tr|A7SX02|A7SX02_NEMVE 170 KLV 172
                             986 PP

>> tr|A7SWX0|A7SWX0_NEMVE  Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g218766 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0     0.023   1.4e+02      21      36 ..      22      36 ..      20      68 .. 0.73
   2 !   21.2   0.0   2.4e-08   0.00015     132     188 ..     399     460 .]     397     460 .] 0.63

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.023
                    TruD 21 speDFiVeEieefsge 36
                            speDFiV+E+ e  ge
  tr|A7SWX0|A7SWX0_NEMVE 22 SPEDFIVTELDEN-GE 36
                            89********554.33 PP

  == domain 2  score: 21.2 bits;  conditional E-value: 2.4e-08
                    TruD 132 irvrdv.aeee...eaakraeeileelkekggvPNyfGvQRFGsr..rpvthlvGkaivkgdl 188
                             i+vr+v + ++     ++ ++  +++++++ g+ NyfG QRFG++    +   vG a+++gd+
  tr|A7SWX0|A7SWX0_NEMVE 399 IKVRGVqPLASssqGITELVKTAVSNVSRH-GFVNYFGPQRFGQEdnSVNASDVGLAMLQGDV 460
                             788887332221112333344444455554.6***********8622568889*******995 PP

>> tr|A7SSD7|A7SSD7_NEMVE  Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g247105 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   8.9e-06     0.055     288     376 ..       6      93 ..       2     109 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 8.9e-06
                    TruD 288 epveGDvvifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelss 374
                             ++v+ D+v++++ ++ ++dr  +v++   +ev++li+ ++  +++  v  +   ++g+ ++ e+e+ e+ g++l+d k  k++ l+s
  tr|A7SSD7|A7SSD7_NEMVE   6 QTVDYDFVLDSNIHVIQPDRGVRVRRWLSHEVEQLIDLFEERPCLWDVSNKEYYQKGNRQRAEEEIAEQMGITLNDVKS-KIKSLRS 91 
                             6788899****9999*************************************************************994.4677777 PP

                    TruD 375 kG 376
                             + 
  tr|A7SSD7|A7SSD7_NEMVE  92 QL 93 
                             64 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                        24428  (8257945 residues searched)
Passed MSV filter:                       759  (0.0310709); expected 488.6 (0.02)
Passed bias filter:                      411  (0.016825); expected 488.6 (0.02)
Passed Vit filter:                        31  (0.00126904); expected 24.4 (0.001)
Passed Fwd filter:                         4  (0.000163747); expected 0.2 (1e-05)
Initial search space (Z):              24428  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.23u 0.01s 00:00:00.24 Elapsed: 00:00:00.10
# Mc/sec: 34353.05
//
[ok]