# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Ornithorhynchus_anatinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    6.4e-71  239.6   0.0    1.7e-65  221.7   0.0    2.3  2  tr|F6ZPP1|F6ZPP1_ORNAN  Pseudouridylate synthase 7 OS=Ornitho
    4.4e-21   75.4   0.1    4.6e-21   75.4   0.1    1.0  1  tr|K7E6L7|K7E6L7_ORNAN  Uncharacterized protein OS=Ornithorhy
    4.1e-20   72.3   0.0    4.6e-20   72.1   0.0    1.0  1  tr|F6Z4V5|F6Z4V5_ORNAN  Uncharacterized protein OS=Ornithorhy


Domain annotation for each sequence (and alignments):
>> tr|F6ZPP1|F6ZPP1_ORNAN  Pseudouridylate synthase 7 OS=Ornithorhynchus anatinus OX=9258 GN=PUS7 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   8.9e-07    0.0064       2      33 ..     122     153 ..     121     203 .. 0.87
   2 !  221.7   0.0   2.4e-69   1.7e-65      39     416 .]     266     656 ..     253     656 .. 0.93

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 8.9e-07
                    TruD   2 lgielyvtdtegigGrlrespeDFiVeEieef 33 
                             +gi  +v++++g+ G l+e++ DF+V+Ei + 
  tr|F6ZPP1|F6ZPP1_ORNAN 122 VGITKFVSKHQGFSGILKERYSDFVVHEIGKD 153
                             89***************************554 PP

  == domain 2  score: 221.7 bits;  conditional E-value: 2.4e-69
                    TruD  39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlG 123
                             +++g+y+ + + k+n dt+d+++ l++ l++  + ++++GtKDkrA+T+Q i++ k+++++l++l   + + +l ++  ++ +l+lG
  tr|F6ZPP1|F6ZPP1_ORNAN 266 KSRGSYCHFVLYKENKDTMDAINVLSKFLRVTPNIFSYMGTKDKRAITVQEIAVLKITAQRLAHLnkCLMNFKLGNFSYQKSPLKLG 352
                             678***********************************************************9996668****************** PP

                    TruD 124 dLaGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedtrea 210
                             +L+GN+F++++r+++ +     ++++ + +l+e g + NyfG+QRFG++   t+ vG+ai+++ + e ++ ++     +e+    + 
  tr|F6ZPP1|F6ZPP1_ORNAN 353 ELQGNHFTVVLRNITGT---DGQVQQAMTSLREIG-FINYFGMQRFGTTAVPTYQVGRAILQNCWTEVMDLILKPRPGAEKGYLVKC 435
                             *************9433...469**********99.*******************************8888888888899999**** PP

                    TruD 211 reavaetgdleealeelpkslryEramlkrLae.kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvi 296
                             re  a+t+d ++al++lp +  +E ++l+ L +   k++ +A+  +p+n + +++h+yqSy++N+++s+R+e++    +pv+GD+v+
  tr|F6ZPP1|F6ZPP1_ORNAN 436 REEWAKTKDPAAALKKLPVKRCVEGQLLRGLSKyGLKNVVSAFGIIPRNNRLMYIHSYQSYVWNNMVSKRIEEY-G-LQPVPGDLVL 520
                             *********************************66799**********************************99.4.48*******9 PP

                    TruD 297 faeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRaill 383
                             +   +         ++e  v++++         v++pl+G+++  ++ + +e  +e+l+ + l+ ++ + +k+ + s +G++R+i++
  tr|F6ZPP1|F6ZPP1_ORNAN 521 KGATA-------IHIEEGDVDSYS------IHDVVMPLPGFDVIYPKHKISEAYKEMLAADSLDIDNMR-HKIRDYSLSGAYRKIII 593
                             99555.......888888888888......45799*********************************9.5689************* PP

                    TruD 384 rve..............................dlelsaeedeltleFsLpkGsYATvvlrEi 416
                             r++                               ++++ + + l++eFsLp+ +YAT+ +rE+
  tr|F6ZPP1|F6ZPP1_ORNAN 594 RPQnvsweviayddpriplfntdvdnlegkpppVFATEGKYRALKMEFSLPPSTYATMAIREV 656
                             ****************************999986666777788******************96 PP

>> tr|K7E6L7|K7E6L7_ORNAN  Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.4   0.1   6.3e-25   4.6e-21      92     201 ..       3     121 ..       1     137 [] 0.75

  Alignments for each domain:
  == domain 1  score: 75.4 bits;  conditional E-value: 6.3e-25
                    TruD  92 irkvepeelekl....eikdvelevvgrarrklrlGdLaGNkFeirvrdv.aeee....eaakraeeileelkekggvPNyfGvQRF 169
                             ++kv pe+l+++    e k++++ ++++ +++lrlG+L+GN+F+i+vrd+  +++    + ++++ e +e++k++g + Ny+G QRF
  tr|K7E6L7|K7E6L7_ORNAN   3 VKKVAPERLKEIrsavEKKGISIYNIHSVHQPLRLGQLTGNHFDITVRDLkRQTSdssaKPKESIVEAIENVKTRG-FINYYGPQRF 88 
                             6788899998886655669******************************954333444433445555555556555.********** PP

                    TruD 170 Gsrrpv.thlvGkaivkgdleeAveayvgkpfe 201
                             G+ ++v t  +G a++++++ +Av+ +++    
  tr|K7E6L7|K7E6L7_ORNAN  89 GQWQSVqTDQIGLALLNNEMVKAVKLFFTPEDL 121
                             **99764899***************99875443 PP

>> tr|F6Z4V5|F6Z4V5_ORNAN  Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 GN=PUS7L PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.1   0.0   6.3e-24   4.6e-20     243     416 .]       8     197 ..       1     197 [. 0.83

  Alignments for each domain:
  == domain 1  score: 72.1 bits;  conditional E-value: 6.3e-24
                    TruD 243 e...kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvifaeer...lpdtdrlqlvteknveevkrli 323
                             +   +++   +   ++p+ ++ ++vhAy S ++N++ s Rle +    ++veGD+v  +e+    lp +dr++++++++ ++     
  tr|F6Z4V5|F6Z4V5_ORNAN   8 RygvTEEGCTRGWLSIPHSMRIFYVHAYCSKIWNEAASFRLETYG--SKVVEGDLVSSEEKGrehLPLSDRVHVISAEEEAANVY-- 90 
                             444466677788889***************************995..69********9988877777777777776554433332.. PP

                    TruD 324 ergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRaillrve................dlelsaee 394
                                  +v++p+vG +   ++ +vg+  re l ++gl++  F++++  +l+  G +R+il  ++                +++ls+e 
  tr|F6Z4V5|F6Z4V5_ORNAN  91 --AIHQVVLPMVGHSIVYPKNKVGQWYRERLGRDGLQTCRFRVSA-LQLNIPGCYRQILKYPRnvsyhlpedgdvdgrmEASLSDEP 174
                             ..334799**********************************998.99**********99999999*********996644444444 PP

                    TruD 395 de.ltleFsLpkGsYATvvlrEi 416
                             +  l ++F L+  +YATv lrEi
  tr|F6Z4V5|F6Z4V5_ORNAN 175 SAsLHISFDLDASCYATVCLREI 197
                             3369******************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                        21677  (8259262 residues searched)
Passed MSV filter:                       725  (0.0334456); expected 433.5 (0.02)
Passed bias filter:                      378  (0.0174378); expected 433.5 (0.02)
Passed Vit filter:                        23  (0.00106103); expected 21.7 (0.001)
Passed Fwd filter:                         3  (0.000138396); expected 0.2 (1e-05)
Initial search space (Z):              21677  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.22u 0.01s 00:00:00.23 Elapsed: 00:00:00.09
# Mc/sec: 38176.14
//
[ok]