# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Pan_troglodytes.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence                       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------                       -----------
    5.1e-74  249.9   0.0    6.3e-70  236.4   0.0    2.1  2  tr|H2R7C1|H2R7C1_PANTR          Pseudouridylate synthase 7 like 
    8.9e-74  249.1   0.0    2.3e-68  231.3   0.0    2.3  2  tr|A0A2I3SFI8|A0A2I3SFI8_PANTR  Uncharacterized protein OS=Pan t


Domain annotation for each sequence (and alignments):
>> tr|H2R7C1|H2R7C1_PANTR  Pseudouridylate synthase 7 like OS=Pan troglodytes OX=9598 GN=PUS7L PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.3   0.0   1.2e-05      0.14       6      36 ..     153     182 ..     149     213 .. 0.74
   2 !  236.4   0.0   5.5e-74   6.3e-70      40     416 .]     434     834 ..     423     834 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 1.2e-05
                    TruD   6 lyvtdtegigGrlrespeDFiVeEieefsge 36 
                             +++ d+ g+ G++++sp DFiV Ei e  g+
  tr|H2R7C1|H2R7C1_PANTR 153 CFFNDHVGFHGTIKSSPSDFIVIEIDEQ-GQ 182
                             6778999******************655.22 PP

  == domain 2  score: 236.4 bits;  conditional E-value: 5.5e-74
                    TruD  40 kegey..lvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..ei..kdvelevvgrarrkl 120
                             +eg++  + ++++k+n ++ +++  la +lg+  +++++aG+KDk+A+T+Q + +rkv+pe+l+++  ei  k++++ ++ + + +l
  tr|H2R7C1|H2R7C1_PANTR 434 QEGKViyTAFTLRKENLEMFEAIGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIekEIekKRMNVFNIRSVDDSL 520
                             45665448899*****************************************************9988444488999999******* PP

                    TruD 121 rlGdLaGNkFeirvrdv.aeee...eaakraeeileelkekggvPNyfGvQRFGsrrpv.thlvGkaivkgdleeAveayvgkpfee 202
                             rlG+L+GN+F+i++r++ ++ +   ++++r+ e +e++k+kg + Ny+G QRFG+ r v t  +G a++k+++ +A++ +++     
  tr|H2R7C1|H2R7C1_PANTR 521 RLGQLKGNHFDIVIRNLkKQINdsaNLRERIMEAIENVKKKG-FVNYYGPQRFGKGRKVhTDQIGLALLKNEMMKAIKLFLTPED-- 604
                             ****************85544444455566666666777766.************8875489******************98765.. PP

                    TruD 203 esedtreareavaetgdleealeelpkslryEramlkrLae...kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpl 286
                              ++ +++a++++ +t+d++  l+++p+    Era+l++L +   +++   +A  +lp+ ++ ++vhAy S ++N+++s Rle +   
  tr|H2R7C1|H2R7C1_PANTR 605 LDDPVNRAKKYFLQTEDAKGTLSLMPEFKVRERALLEALHRfgmTEEGCIQAWFSLPHSMRIFYVHAYTSKIWNEAVSYRLETY--G 689
                             45556799*********************************88888889999999***************************99..5 PP

                    TruD 287 depveGDvvifaeer...lpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklp 370
                              ++v+GD+v+ +e+    +  +++++lvte++  +          +v++p++G++ + ++ +vg+  +++l+++gl++  Fk+p+  
  tr|H2R7C1|H2R7C1_PANTR 690 ARVVQGDLVCLDEDIddeNFPNSKIHLVTEEEGSANMYA----IHQVVLPILGYNIQYPKNKVGQWYHDILSRDGLQTCRFKVPT-L 771
                             7**********9877666666777888877665544433....34799************************************8.9 PP

                    TruD 371 elsskGtrRaillrve.................dlelsaeede...ltleFsLpkGsYATvvlrEi 416
                             +l++ G +R+il +++                   ++ +   +   l+++F L+  +YATv l+Ei
  tr|H2R7C1|H2R7C1_PANTR 772 KLNVPGCYRQILKHPRnlsyqlmedhdidvktkGSHIGE---TalsLLISFDLDASCYATVCLKEI 834
                             *************9999999999*997766443223333...145599****************97 PP

>> tr|A0A2I3SFI8|A0A2I3SFI8_PANTR  Uncharacterized protein OS=Pan troglodytes OX=9598 GN=PUS7 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   6.1e-07     0.007       2      32 ..     114     144 ..     113     194 .. 0.87
   2 !  231.3   0.0     2e-72   2.3e-68      39     416 .]     258     648 ..     245     648 .. 0.93

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 6.1e-07
                            TruD   2 lgielyvtdtegigGrlrespeDFiVeEiee 32 
                                     +gi  +v++++g+ G l+e++ DF+V+Ei +
  tr|A0A2I3SFI8|A0A2I3SFI8_PANTR 114 VGITKFVSSHQGFSGILKERYSDFVVHEIGK 144
                                     89***************************54 PP

  == domain 2  score: 231.3 bits;  conditional E-value: 2e-72
                            TruD  39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgr 115
                                     +++g+y+ + + k+n dt+d+++ l++ l+++ + ++++GtKDkrA+T+Q i++ k+++++l++l   + + +l ++  
  tr|A0A2I3SFI8|A0A2I3SFI8_PANTR 258 KSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITVQEIAVLKITAQRLAHLnkCLMNFKLGNFSY 336
                                     678***********************************************************9996668********** PP

                            TruD 116 arrklrlGdLaGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAvea 194
                                     ++++l+lG+L+GN+F++++r+++ ++   +++++ +++lke g + Ny+G+QRFG++   t+ vG+ai+++ + e ++ 
  tr|A0A2I3SFI8|A0A2I3SFI8_PANTR 337 QKNPLKLGELQGNHFTVVLRNITGTD---DQVQQAMNSLKEIG-FINYYGMQRFGTTAVPTYQVGRAILQNSWTEVMDL 411
                                     *********************95444...59**********99.*******************************9999 PP

                            TruD 195 yvgkpfeeesedtreareavaetgdleealeelpkslryEramlkrLae.kpkdykkAlealpknLqrlFvhAyqSylF 272
                                     ++   + +e+    + re  a+t+d ++al++lp +  +E ++l+ L +   k++ +A+  +p+n + +++h+yqSy++
  tr|A0A2I3SFI8|A0A2I3SFI8_PANTR 412 ILKPRSGAEKGYLVKCREEWAKTKDPTAALRKLPVKRCVEGQLLRGLSKyGMKNIVSAFGIIPRNNRLMYIHSYQSYVW 490
                                     9999999******************************************77899************************* PP

                            TruD 273 NrvlseRlerglpldepveGDvvifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeier 351
                                     N+++s+R+e++    +pv+GD+v++   +         ++e+ v++++         v++pl+G+++  ++ + +e  r
  tr|A0A2I3SFI8|A0A2I3SFI8_PANTR 491 NNMVSKRIEDY-G-LKPVPGDLVLKGATA-------TYIEEDDVNNYS------IHDVVMPLPGFDVIYPKHKIQEAYR 554
                                     *********99.4.48*******999554.......667776666666......45799******************** PP

                            TruD 352 evleeegleledFklpklpelsskGtrRaillrve..............................dlelsaeedeltle 400
                                     e+l  ++l+ ++ + +k+ + s +G++R+i++r++                               ++ + + + l+++
  tr|A0A2I3SFI8|A0A2I3SFI8_PANTR 555 EMLTADNLDIDNMR-HKIRDYSLSGAYRKIIIRPQnvswevvayddpkiplfntdvdnlegktppVFASEGKYRALKMD 632
                                     *************9.5689****************************************9999875666666777**** PP

                            TruD 401 FsLpkGsYATvvlrEi 416
                                     FsLp+ +YAT+ +rE+
  tr|A0A2I3SFI8|A0A2I3SFI8_PANTR 633 FSLPPSTYATMAIREV 648
                                     **************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                        23008  (11942255 residues searched)
Passed MSV filter:                       838  (0.0364221); expected 460.2 (0.02)
Passed bias filter:                      389  (0.0169072); expected 460.2 (0.02)
Passed Vit filter:                        39  (0.00169506); expected 23.0 (0.001)
Passed Fwd filter:                         2  (8.69263e-05); expected 0.2 (1e-05)
Initial search space (Z):              23008  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.32u 0.02s 00:00:00.34 Elapsed: 00:00:00.12
# Mc/sec: 41399.82
//
[ok]