# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence             Description
    ------- ------ -----    ------- ------ -----   ---- --  --------             -----------
      8e-76  254.0   0.7    7.2e-71  237.6   0.3    3.2  2  sp|Q08647|PUS7_YEAST  Multisubstrate pseudouridine synthase 7


Domain annotation for each sequence (and alignments):
>> sp|Q08647|PUS7_YEAST  Multisubstrate pseudouridine synthase 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.0   1.1e-05     0.068       3      33 ..      44      75 ..      42      89 .. 0.76
   2 !  237.6   0.3   1.2e-74   7.2e-71      42     416 .]     217     658 ..     194     658 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 1.1e-05
                  TruD  3 gielyvt.dtegigGrlrespeDFiVeEieef 33
                          gi l+++ + +g+ G++++++ DF+V+Ei + 
  sp|Q08647|PUS7_YEAST 44 GITLFLSpELPGFRGQIKQRYTDFLVNEIDQE 75
                          66666553679******************443 PP

  == domain 2  score: 237.6 bits;  conditional E-value: 1.2e-74
                  TruD  42 geylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlGdLaGN 128
                            +++ ++++k+n dt+++v+ +++ l++ ++ +++aGtKD+rAvT Q +si+k+  ++l++l  ++k++ + +   ++ +l+lGdL+GN
  sp|Q08647|PUS7_YEAST 217 KDFIHFTLHKENKDTMEAVNVITKLLRVPSRVIRYAGTKDRRAVTCQRVSISKIGLDRLNALnrTLKGMIIGNYNFSDASLNLGDLKGN 305
                           467999****************************************************99998899*********************** PP

                  TruD 129 kFeirvrdv.aeee..eaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedtreareav 214
                           +F +++rdv + ++  ++++ +++  ++l+e+g + NyfG+QRFG+    th++G++++  ++++A+e +++++ +  ++ ++ear++ 
  sp|Q08647|PUS7_YEAST 306 EFVVVIRDVtTGNSevSLEEIVSNGCKSLSENG-FINYFGMQRFGTFSISTHTIGRELLLSNWKKAAELILSDQDNVLPK-SKEARKIW 392
                           ********9543334455677788888899988.*********************************9999988766655.59****** PP

                  TruD 215 aetgdleealeelpkslryEramlkrLae.........kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDv 294
                           aet+d++ al+++p+++  E a+l +L +         ++++y  A+ ++p+nL+ ++vhAyqSy++N + s+R+e      + v GD+
  sp|Q08647|PUS7_YEAST 393 AETKDAALALKQMPRQCLAENALLYSLSNqrkeedgtySENAYYTAIMKIPRNLRTMYVHAYQSYVWNSIASKRIELH--GLKLVVGDL 479
                           *****************************9999999999999**********************************65..4589***** PP

                  TruD 295 vifaeer.................lpdtdrlqlvteknveevkrliergrafvtaplvGtetelae.gevgeierevleeegleledFk 365
                           vi+++e+                  ++  r ++vt++ ++     ++     v++p +G+++  ++ +e +++  ++l+ +++++ + +
  sp|Q08647|PUS7_YEAST 480 VIDTSEKsplisgiddedfdedvrEAQFIRAKAVTQEDID----SVKYTMEDVVLPSPGFDVLYPSnEELKQLYVDILKADNMDPFNMR 564
                           ****9999*****999998543333333333333333333....4555556799*******9876515678999********9997777 PP

                  TruD 366 lpklpelsskGtrRaillrve..............................................dlelsaeedeltleFsLpkGsY 408
                             k+ ++s +G++R ++ +++                                              d     e++ ++l+F+L    Y
  sp|Q08647|PUS7_YEAST 565 -RKVRDFSLAGSYRTVIQKPKsleyriihyddpsqqlvntdldilnntrakesgqkymkakldrympD--KGGEKTAVVLKFQLGTSAY 650
                           .5678****************9********************************99999988655321..233445599********** PP

                  TruD 409 ATvvlrEi 416
                           AT+ lrE+
  sp|Q08647|PUS7_YEAST 651 ATMALREL 658
                           ******95 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                         6049  (2936363 residues searched)
Passed MSV filter:                       230  (0.0380228); expected 121.0 (0.02)
Passed bias filter:                      125  (0.0206646); expected 121.0 (0.02)
Passed Vit filter:                        13  (0.00214912); expected 6.0 (0.001)
Passed Fwd filter:                         1  (0.000165317); expected 0.1 (1e-05)
Initial search space (Z):               6049  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.11u 0.00s 00:00:00.11 Elapsed: 00:00:00.05
# Mc/sec: 24430.54
//
[ok]