# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TruD.hmm.txt
# target sequence database: proteomes/Tetrahymena_thermophila.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TruD [M=416]
Accession: PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.3e-68 232.4 9.1 1.4e-65 222.4 5.8 2.7 2 tr|I7M0J5|I7M0J5_TETTS tRNA pseudouridine synthase D OS=Tetr
4.7e-36 125.1 4.6 5.4e-36 124.9 4.6 1.0 1 tr|I7MHN1|I7MHN1_TETTS tRNA pseudouridine synthase D OS=Tetr
------ inclusion threshold ------
0.086 12.2 0.1 0.086 12.2 0.1 1.5 2 tr|I7MKR3|I7MKR3_TETTS ABC transporter family protein OS=Tet
Domain annotation for each sequence (and alignments):
>> tr|I7M0J5|I7M0J5_TETTS tRNA pseudouridine synthase D OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 10.5 0.0 3.3e-05 0.29 2 34 .. 13 45 .. 12 68 .. 0.82
2 ! 222.4 5.8 1.5e-69 1.4e-65 38 416 .] 168 598 .. 133 598 .. 0.86
Alignments for each domain:
== domain 1 score: 10.5 bits; conditional E-value: 3.3e-05
TruD 2 lgielyvtdtegigGrlrespeDFiVeEieefs 34
+gi ++t+ +++ G ++ + +DFiV+E+++ +
tr|I7M0J5|I7M0J5_TETTS 13 VGITAFLTQGKPFKGIVKYRIQDFIVNEVTQEK 45
899**************************5442 PP
== domain 2 score: 222.4 bits; conditional E-value: 1.5e-69
TruD 38 eakegey....lvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisi.rkvepeelekl.....eikdvelevvg 114
+ak+g+ + + + k+++d ++++++++ l++ k+++ aG+KDkr++TtQlisi + +++e+ + + +++++++v
tr|I7M0J5|I7M0J5_TETTS 168 KAKRGKIdqkvYHCVLFKNGIDNFTAIQNISKYLRLPPKNINAAGIKDKRGITTQLISIaMSNTSAEILNQrfqnsRWNNMKVQNVK 254
333343333348999*******************************************95445555555444666688********* PP
TruD 115 rarrklrlGdLaGNkFeirvrdv.aeeeeaakraeeileelkekggvPNyfGvQRFGsrrpv.thlvGkaivkgdleeAveayvgkp 199
a +lr+GdL+GN+F + +r v e ++++ + +e+lk+ g + NyfG+QRFG++ ++ th++G i+k+++e+ ++++vg+
tr|I7M0J5|I7M0J5_TETTS 255 DATSQLRTGDLYGNRFSLAIRLVsY--E--EQEVIKAVEDLKKLG-FINYFGMQRFGTNNSIhTHEIGLLILKRQWEQVFDSIVGQE 336
**********************833..3..257888889999998.***********9987559*********************98 PP
TruD 200 feeesedtreareav.aetgdleealeelpkslryEramlkrLae..kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerg 283
+++ ++++ea++a+ +++ ++ al+++p ++++Er++l+ + + ++++ +A+ l++ ++l+ hAyqSy++N + s R++
tr|I7M0J5|I7M0J5_TETTS 337 TND--KRVNEAKKAFlKDKTQIRDALRDIPFKYKIERTLLQGYERvgMKNNFLQAICFLNRSTRNLYCHAYQSYIWNLLASYRIQTL 421
855..455566555427899***********************9988999***********************************87 PP
TruD 284 lpldepveGDvvifaeer..................lpdtdrlqlvteknveevkrl.iergr.afvtaplvGtetelaeg.evgei 349
++ v+GD+v +++e+ + ++++ q + + ++e ++ i++ + v +p++G + +++e + +++
tr|I7M0J5|I7M0J5_TETTS 422 --GNQLVKGDIVAKKRENflidveaeveeengqeeeQEEESKYQSIGDYEIEVIDDSnIDKYTlYDVLIPIIGGKLKIPENfNLNAY 506
..58***********999**************999888999999*******999864144444157999*********988356789 PP
TruD 350 erevleeegleledFk.lpklpelsskGtrRaillrve..........................dlelsaeedeltleFsLpkGsYA 409
++le++gl+++ F+ ++k e+ ++G +R ++++ e + e + + + l+l+F+L kGsYA
tr|I7M0J5|I7M0J5_TETTS 507 LTSILEKDGLDQQLFEkIQK--EFFVEGGYRFLICQAEdvqysinkyneknqdiltpyynvqqdHSEENGKYSALCLKFTLAKGSYA 591
99**************7877..*************************************997532222333344************* PP
TruD 410 TvvlrEi 416
T+++rE+
tr|I7M0J5|I7M0J5_TETTS 592 TMLIREL 598
*****95 PP
>> tr|I7MHN1|I7MHN1_TETTS tRNA pseudouridine synthase D OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 124.9 4.6 6e-40 5.4e-36 39 243 .. 23 233 .. 11 244 .] 0.82
Alignments for each domain:
== domain 1 score: 124.9 bits; conditional E-value: 6e-40
TruD 39 akegey....lvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisi.rkvepeelekl.....eikdvelevvgr 115
ak+g+ + + + k+++d ++++++++ l++ k+++ aG+K kr++Tt+lisi + +++e+ + + +++++++v
tr|I7MHN1|I7MHN1_TETTS 23 AKRGKIdqkvYNCVLFKNGIDNFTAIQNISKYLRLPPKNINAAGIKEKRGITTHLISIaMSNTSAEILNQrfqnsRWNKMKFQNVKD 109
4444333333788999*****************************************954455555554446666889********* PP
TruD 116 arrklrlGdLaGNkFeirvrdv.aeeeeaakraeeileelkekggvPNyfGvQRFGsrrpv.thlvGkaivkgdleeAveayvgkpf 200
a klr GdL+GN+F + ++ v e ++++ + +e+lk+ + + NyfG+QRFG++ ++ th++G i+k++ e+ ++++vg+ +
tr|I7MHN1|I7MHN1_TETTS 110 ATSKLRAGDLYGNRFSLAIKLVsY--E--EQEVIKAVEDLKKLR-FINYFGMQRFGTNNSIhTHEIGLLILKRQQEQVFDSIVGQET 191
*********************833..2..256888888999999.***********9987559*********************988 PP
TruD 201 eeesedtreareav.aetgdleealeelpkslryEramlkrLae 243
++ ++++ea++a+ +++ ++ al+ +p ++++Er++l+ + +
tr|I7MHN1|I7MHN1_TETTS 192 ND--KRVNEAKKAFlKDKTQIRDALRGIPFKYKIERTLLQGYER 233
55..455566555427899*********************9887 PP
>> tr|I7MKR3|I7MKR3_TETTS ABC transporter family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -4.0 0.2 0.82 7.4e+03 322 364 .. 716 757 .. 690 761 .. 0.50
2 ? 12.2 0.1 9.6e-06 0.086 2 72 .. 1045 1117 .. 1044 1120 .. 0.89
Alignments for each domain:
== domain 1 score: -4.0 bits; conditional E-value: 0.82
TruD 322 liergrafvtaplvGtetelaegevgeierevleeegleledF 364
li+ + + e ++ + +++ e+++l++++ + e+F
tr|I7MKR3|I7MKR3_TETTS 716 LIDTDKNKHIQQNQNKEITI-QASQSKAENSILSDQNKKEEEF 757
44444444444444444333.3344455555555555555544 PP
== domain 2 score: 12.2 bits; conditional E-value: 9.6e-06
TruD 2 lgielyvtdtegigGrlrespeDFiVeEieef.sge.eeakegeylvlrvekrnwdtldlvrelaralgisrk 72
+++++++t++e + ++ +e V+E+e ++e +++ +++y +++ ++n+d+ +++ +++++ +i+++
tr|I7MKR3|I7MKR3_TETTS 1045 INMDTFMTSSERAQSIIKLPKEKIEVSEVECQqQQEsSNSIKNSYQNYNLVQTNIDQDTVIIDISKQGNINNS 1117
79***************************8885444457777999**********************999876 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (416 nodes)
Target sequences: 26971 (16912921 residues searched)
Passed MSV filter: 2026 (0.0751177); expected 539.4 (0.02)
Passed bias filter: 227 (0.00841645); expected 539.4 (0.02)
Passed Vit filter: 14 (0.000519076); expected 27.0 (0.001)
Passed Fwd filter: 3 (0.000111231); expected 0.3 (1e-05)
Initial search space (Z): 26971 [actual number of targets]
Domain search space (domZ): 3 [number of targets reported over threshold]
# CPU time: 0.41u 0.02s 00:00:00.43 Elapsed: 00:00:00.21
# Mc/sec: 33503.69
//
[ok]