# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Trichomonas_vaginalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.3e-67  230.0   2.3    1.4e-62  213.4   0.9    3.2  2  tr|A2EJH2|A2EJH2_TRIVA  Uncharacterized protein OS=Trichomona
    2.5e-66  225.7   8.4    6.5e-62  211.1   7.0    3.5  2  tr|A2FUM2|A2FUM2_TRIVA  Uncharacterized protein OS=Trichomona


Domain annotation for each sequence (and alignments):
>> tr|A2EJH2|A2EJH2_TRIVA  Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_050450 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.0     3e-06     0.074       2      32 ..       9      39 ..       8      52 .. 0.86
   2 !  213.4   0.9   5.5e-67   1.4e-62      44     416 .]     115     501 ..      94     501 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 3e-06
                    TruD  2 lgielyvtdtegigGrlrespeDFiVeEiee 32
                            +gi  y  d  g++G +++++ DF V+Ei +
  tr|A2EJH2|A2EJH2_TRIVA  9 VGITEYNNDFAGMNGIIKHRYSDFHVHEIDQ 39
                            899**************************43 PP

  == domain 2  score: 213.4 bits;  conditional E-value: 5.5e-67
                    TruD  44 y.lvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl.ei.kdvelevvgrarrklrlGdLaG 127
                             + + + + k+n ++++ +++l+++l+i+++++g+aG KDkrA+TtQ+++ir+v  ++le+l ++ ++++   + +a ++++lGdL G
  tr|A2EJH2|A2EJH2_TRIVA 115 MvISMVICKENTNQQESISKLSKKLNIKKNQIGIAGNKDKRAITTQVMTIRDVGINSLEQLaNLtDKIKCGMFYQAMNPVNLGDLNG 201
                             33668899********************************************999999998744599******************** PP

                    TruD 128 NkFeirvrdv.aeee......eaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedt 207
                             N+F++++r++    +      e+++ ++  +e+l+ekg + NyfG+QRFG++ + th++G ai+++++++ ++ ++  p e ++ed+
  tr|A2EJH2|A2EJH2_TRIVA 202 NHFTLVLRNLtI--PgcetveELREGLKIRMEALSEKG-FINYFGMQRFGTTAMSTHTIGIAILRKEWQKVID-MIMSPIEGNQEDV 284
                             *********743..334455567777777888899887.******************************9765.7889********* PP

                    TruD 208 reareavaetgdleealeelpkslryEramlkrLaekpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDv 294
                             ++a++++++t+d+e+a+ ++pk+  +E+++l + ++  k+  + +++++++ + l+ hAyqSy++N++ s+R++r     ++v+GD+
  tr|A2EJH2|A2EJH2_TRIVA 285 NKAKTIYMKTHDAEKAYALMPKHAATEKSILAAAKKGIKNPFELFKVIDRRQRLLYCHAYQSYVWNHCASARVKRS-G-FKVVPGDI 369
                             **************************************************************************99.4.48****** PP

                    TruD 295 vifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRai 381
                             v ++++         +v++ n  +++     +++++ +p  G+         +   +e+l+++g+e+++F+++k  el+  G++R++
  tr|A2EJH2|A2EJH2_TRIVA 370 VEENRNY-------VTVKAGNESKYS----PFDIVIPLPADGC--------ISPDAEELLKKDGIEQSMFSAQK--ELGLVGDYRKL 435
                             *777444.......555555544444....5555555544444........3344579***************9..*********** PP

                    TruD 382 llrve................................dlelsaeede.......ltleFsLpkGsYATvvlrEi 416
                             + +++                                +                +++eFsL + +YAT+ +rE+
  tr|A2EJH2|A2EJH2_TRIVA 436 FAQPTdisfdiiehddndaelidsdidklegrtnkgnH--------VpggkfksAVVEFSLGPSQYATMCMREL 501
                             ***999******************99998777654321........1222334599****************95 PP

>> tr|A2FUM2|A2FUM2_TRIVA  Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_350960 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.8   0.0   3.4e-05      0.85       2      34 ..      10      39 ..       9      51 .. 0.84
   2 !  211.1   7.0   2.6e-66   6.5e-62      43     416 .]     115     488 ..      94     488 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 3.4e-05
                    TruD  2 lgielyvtdtegigGrlrespeDFiVeEieefs 34
                            +g   ++ +++g++G +++++ DF V+Ei   +
  tr|A2FUM2|A2FUM2_TRIVA 10 VGCTRFANESSGFDGIIKHKYSDFHVHEI---D 39
                            78889999*********************...3 PP

  == domain 2  score: 211.1 bits;  conditional E-value: 2.6e-66
                    TruD  43 eylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlGdLaG 127
                             e + +++ k+n+++++++ ++  +l+i ++++gfaG KDkrA TtQ++++r+v  +++ k   ++++v+  ++ +   +l+lGdL G
  tr|A2FUM2|A2FUM2_TRIVA 115 EITRFTLFKENVNQQEAMAKILARLNITQNQLGFAGNKDKRAATTQYVTVRDVPLQKVVKSlsNLDKVTCGEFCHVTSPLKLGDLSG 201
                             44778899********************************************999997766699*********************** PP

                    TruD 128 NkFeirvrdv.aeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedtrearea 213
                             N+F+i +r++       +k+++e ++++++ g + Ny+G+QRFG+  + th++G  i++g++++Av+a + +p e e+++++ea+ a
  tr|A2FUM2|A2FUM2_TRIVA 202 NRFTIAIRGLkI--G--QKELDEKIKSIQKSG-FINYYGMQRFGTGETATHKIGILIIQGKYDAAVDA-IMNPVEGEEQRIHEAKIA 282
                             *********833..2..468999999999988.*********************************98.679*************** PP

                    TruD 214 vaetgdleealeelpkslryEramlkrLaekpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvifaee 300
                             + ++ dl++a+e+lp+s   Er+++++  +++k+y + ++a++++ ++++vhAyqSy++N++ s+R e+g+   +++e D+v ++ +
  tr|A2FUM2|A2FUM2_TRIVA 283 F-QRSDLDKAMELLPHSAVAERKIVEAAHDTNKKY-EMFKAVDRRQRMMYVHAYQSYIWNKCASKRAEKGF---KVLETDTVEYKGK 364
                             *.9************************99966666.56********************************5...689*****99955 PP

                    TruD 301 rlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRaillrve. 386
                               +++++ +++++  +  ++     g+    ++    +++ ++g + e+ r++ +e+g+++e  k+ ++ +  +   +++       
  tr|A2FUM2|A2FUM2_TRIVA 365 I-KEPTKKSVLQDVVIPLCE-----GDTKDKMI---LDMMKEDGVTTEMFRKIAKEYGINTEYRKFMAFAKDIEYSIVKHDN---Pd 439
                             4.455555555444444444.....33322222...2566678888888888888888877644433322211111121111...02 PP

                    TruD 387 ...................dlelsaeedeltleFsLpkGsYATvvlrEi 416
                                                  ++ +++++++++FsL +G YAT++lrE+
  tr|A2FUM2|A2FUM2_TRIVA 440 vqlinndvellnnpklsrvAKNTGNKNSSAVISFSLGSGEYATMFLREL 488
                             22334457788888898775556677778******************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                        50190  (17055200 residues searched)
Passed MSV filter:                      1987  (0.0395896); expected 1003.8 (0.02)
Passed bias filter:                      738  (0.0147041); expected 1003.8 (0.02)
Passed Vit filter:                        35  (0.00069735); expected 50.2 (0.001)
Passed Fwd filter:                         2  (3.98486e-05); expected 0.5 (1e-05)
Initial search space (Z):              50190  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.02s 00:00:00.49 Elapsed: 00:00:00.21
# Mc/sec: 33785.54
//
[ok]