# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Trichoplax_adhaerens.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    3.9e-72  242.7   0.0    3.8e-65  219.7   0.0    3.3  3  tr|B3RVM0|B3RVM0_TRIAD  Uncharacterized protein OS=Trichoplax
    1.6e-66  224.3   0.0    2.4e-66  223.7   0.0    1.2  1  tr|B3RRZ1|B3RRZ1_TRIAD  Uncharacterized protein OS=Trichoplax


Domain annotation for each sequence (and alignments):
>> tr|B3RVM0|B3RVM0_TRIAD  Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_23629 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   1.1e-07   0.00062       2      32 ..      61      91 ..      60     103 .. 0.87
   2 ?   -2.7   0.0      0.21   1.2e+03     211     247 ..     115     149 ..     102     161 .. 0.70
   3 !  219.7   0.0   6.6e-69   3.8e-65      39     416 .]     215     601 ..     202     601 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 1.1e-07
                    TruD  2 lgielyvtdtegigGrlrespeDFiVeEiee 32
                            +gi  y+++ ++i+G+++++  DFiV+Ei+ 
  tr|B3RVM0|B3RVM0_TRIAD 61 VGITEYISQLDPIQGSIKQRFADFIVHEINL 91
                            89***************************54 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.21
                    TruD 211 reavaetgdleealeelpkslryEramlkrLaekpkd 247
                              +++  + dle+ l+el +s +  ++++  L+e++ +
  tr|B3RVM0|B3RVM0_TRIAD 115 DNMI--STDLENRLQELSSSHSSKKSVIIDLKENESN 149
                             3333..7899999999999999999999999995433 PP

  == domain 3  score: 219.7 bits;  conditional E-value: 6.6e-69
                    TruD  39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeeleklei..kdvelevvgrarrklrlG 123
                             +++++y+ +r+ k+n+dt+++++ + + +g++ + +g+aGtKD+rA+TtQ i+  kv p++l++++   ++v+l ++  ++ +l+lG
  tr|B3RVM0|B3RVM0_TRIAD 215 NEHDKYCKFRLYKENIDTMNAINLICKFTGLKPSIFGYAGTKDRRAITTQEITAFKVLPSKLHHVNSvtHKVRLGNFTYSKDRLTLG 301
                             567899*******************************************************999954469***************** PP

                    TruD 124 dLaGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvgkpfeeesedtrea 210
                             dLaGN+F++++r+v+ +   ++++e+ +++lke+g + Ny+G+QRFG+    t+ +Gka++ g++++ +e ++ kp+ ++s +t ea
  tr|B3RVM0|B3RVM0_TRIAD 302 DLAGNHFTLTLRNVKGS---EEQIEKSMASLKETG-FINYYGLQRFGTSHIPTYQIGKALLLGNWRKSIE-LILKPTRTDSFRTMEA 383
                             *************8433...469**********99.********************************97.6779999********* PP

                    TruD 211 reavaetgdleealeelpkslryEramlkrLae.kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvvi 296
                             re+ ++++d ++al++l ++  +E  +lk L+e  +++   A+ ++p+n + l+v +yqS ++N v s+R+++     +pv GD+vi
  tr|B3RVM0|B3RVM0_TRIAD 384 REHWWQHRDPSAALRLLRSRRGIEYYLLKGLVEhGSTSPVTAIMKIPRNARLLYVYSYQSLIWNLVASRRIKEF-G-LKPVVGDLVI 468
                             *********************************3456689********************************98.4.48******** PP

                    TruD 297 faeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRaill 383
                              ++ r           ++ + +++         +++pl+G++++ ++ e+++  ++ ++ +g++ ++ +  + +e+s  G +R++++
  tr|B3RVM0|B3RVM0_TRIAD 469 SNSAR-----------QQDLPHYS------IHDIVLPLPGYNVMYPQHEANDWYHQQMKADGISIKNLENRH-KEFSLCGMYRKLVV 537
                             99655...........33333333......34689**********************************554.7************* PP

                    TruD 384 rve..............................dlelsaeede.ltleFsLpkGsYATvvlrEi 416
                             r++                              ++++ + ++  l+l+FsLp+ sYAT+ lrE+
  tr|B3RVM0|B3RVM0_TRIAD 538 RPKnlswstaryddftiplystdldqirqnkiiNNSVADGKNLaLLLSFSLPPSSYATMALREV 601
                             ****************************99987444444443359******************6 PP

>> tr|B3RRZ1|B3RRZ1_TRIAD  Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_22091 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.7   0.0   4.1e-70   2.4e-66      38     416 .]     203     629 ..     187     629 .. 0.86

  Alignments for each domain:
  == domain 1  score: 223.7 bits;  conditional E-value: 4.1e-70
                    TruD  38 eakegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl.....eikdvelevvgrarrk 119
                             ++++  yl + ++krn++tld+++++a+alg + +++++aG+KD rA+T+Q +++++v+p+++ ++     + ++++  + +  + +
  tr|B3RRZ1|B3RRZ1_TRIAD 203 NNDNPLYLKFILRKRNVETLDAIHKIAKALGCHLSDFSYAGIKDCRAITYQQVTVKNVKPQQMINAlqkikSQEHIQYGNYQFIHTP 289
                             34445569999***************************************************76666744444788889999999** PP

                    TruD 120 lrlGdLaGNkFeirvrdv.aeee........eaakraeeileelkekggvPNyfGvQRFGsr..rpvthlvGkaivkgdleeAveay 195
                             +rlG+L+GN+F+i +rd+  +++        ++ +++ + +ee+k++g + NyfG QRFG++    +++ +G a++++d + Ave +
  tr|B3RRZ1|B3RRZ1_TRIAD 290 IRLGQLKGNRFRILLRDIrLQDHdsslidiaDLHSQIIQSMEEVKKQG-FINYFGNQRFGKTisTVNSYDIGLAMLRRDEKMAVELI 375
                             ******************754447999988888888999999999988.***********96336799******************* PP

                    TruD 196 vgkpfeeese.dtreareavaetgdleealeelpkslryEramlkrLae...kpkdykkAlealpknLqrlFvhAyqSylFNrvlse 278
                             +++  e+ s+  t +a +++  +gdl + l+++p+  +    +lk+L +   + + y+kAl ++p+n++++++h+y S l+Nr+++ 
  tr|B3RRZ1|B3RRZ1_TRIAD 376 LSTVDEDISDnATMQALKYYHTSGDLVSTLKKIPSYKSRVYLILKALHRygqNIEGYRKALLNIPHNMRKIYIHSYCSLLWNRLVNY 462
                             **99988765157899999*9**************999888899999985556677******************************* PP

                    TruD 279 RlerglpldepveGDvvifaeer.lpdtdrlqlvteknveevkrl....ier.grafvtaplvGtetelaegevgeierevleeegl 359
                             R+e++    ++veGD+v+  + + +pd++++++++++++ ++  +    +++ +   v++pl+G++t  ++   g + +++l+++g+
  tr|B3RRZ1|B3RRZ1_TRIAD 463 RIEKY--GYNVVEGDLVLLGNVDnKPDSTDTDAINQDQLVKLVTKtdlaLNKyNIYDVVLPLLGSKTIYPSNTSGSVYKDMLANDGI 547
                             ***99..468*******998766689999999999988655433311113331445799**************************** PP

                    TruD 360 eledFklpklpelsskGtrRaillrve..........................dlelsaeedeltleFsLpkGsYATvvlrEi 416
                             + ++F  p + +++ kG++R+il  ++                          ++++ +++ +++le +L++GsYATv lrEi
  tr|B3RRZ1|B3RRZ1_TRIAD 548 NDSSFVNP-MLNIKIKGAYRKILSVPKdvnfslhilncqhlhddchdccsnilKNQTCNSRFHFKLEMTLNPGSYATVCLREI 629
                             *****977.79***********999999*****************9999876543434444458999999************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                        11518  (5222075 residues searched)
Passed MSV filter:                       497  (0.0431499); expected 230.4 (0.02)
Passed bias filter:                      221  (0.0191874); expected 230.4 (0.02)
Passed Vit filter:                        12  (0.00104185); expected 11.5 (0.001)
Passed Fwd filter:                         2  (0.000173641); expected 0.1 (1e-05)
Initial search space (Z):              11518  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.16u 0.01s 00:00:00.17 Elapsed: 00:00:00.07
# Mc/sec: 31034.05
//
[ok]