# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TruD.hmm.txt
# target sequence database:        proteomes/Xenopus_tropicalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TruD  [M=416]
Accession:   PF01142.17
Description: tRNA pseudouridine synthase D (TruD)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    3.1e-73  247.4   0.0    6.1e-68  230.0   0.0    2.3  2  tr|F6SUC6|F6SUC6_XENTR  Pseudouridine synthase 7 OS=Xenopus t
    1.7e-72  245.0   0.1    1.4e-66  225.5   0.0    2.1  2  tr|A9JTM8|A9JTM8_XENTR  LOC100127797 protein OS=Xenopus tropi


Domain annotation for each sequence (and alignments):
>> tr|F6SUC6|F6SUC6_XENTR  Pseudouridine synthase 7 OS=Xenopus tropicalis OX=8364 GN=pus7 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   8.8e-07     0.011       2      32 ..     102     132 ..     101     148 .. 0.89
   2 !  230.0   0.0     5e-72   6.1e-68      39     416 .]     240     631 ..     229     631 .. 0.93

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 8.8e-07
                    TruD   2 lgielyvtdtegigGrlrespeDFiVeEiee 32 
                             +gi  +v+ +eg+ G l+e++ DF+V+Ei +
  tr|F6SUC6|F6SUC6_XENTR 102 VGITKFVSTHEGFSGILKERYSDFVVHEIGK 132
                             89**************************943 PP

  == domain 2  score: 230.0 bits;  conditional E-value: 5e-72
                    TruD  39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlG 123
                             + +g+y+ + + k+n dt+d+++ l++ l+i+ + ++++GtKDkrA+T+Q i++ k+++++l++l   + + +l ++  ++++l+lG
  tr|F6SUC6|F6SUC6_XENTR 240 KARGSYCHFVLYKENKDTMDAINVLSKFLRIKPNIFSYMGTKDKRAITVQEIAVLKITAQRLAHLnkCLMNFKLGNFSYQKNPLKLG 326
                             567***********************************************************9996668****************** PP

                    TruD 124 dLaGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvg.kpfeeesedtre 209
                             +L+GN+F++++r+v+    +++++ + + +l++ g + Ny+G+QRFG++   t+ vG+ai++ +++e v+ ++  +p e+e+    +
  tr|F6SUC6|F6SUC6_XENTR 327 ELQGNHFTVVLRNVTG---TSEQIVQAMTSLRDIG-FINYYGMQRFGTTAVPTYQVGRAILQSNWNEMVDLILKpRPGEAEKGYLVQ 409
                             *************943...3458888888999998.*********************************98885378889999999* PP

                    TruD 210 areavaetgdleealeelpkslryEramlkrLae.kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvv 295
                              re  a+t+d e+al++lp +  +E ++l+ L     k++ +A+  +p+n + +++h+yqSy++N+++s+R+e++    ++v+GD+v
  tr|F6SUC6|F6SUC6_XENTR 410 CREEWAKTKDPEAALRKLPVKRCVEGQLLRGLSMyGLKNIVSAFGIIPRNNRLMYIHSYQSYVWNNMVSKRIEEY-G-LKVVPGDLV 494
                             ********************************9966799**********************************99.4.48******* PP

                    TruD 296 ifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRail 382
                             ++ + +         v+e nv++++         +++pl+G+++  ++ +v +  +e+l+ ++l+ ++ + +++++ s +G++R+i+
  tr|F6SUC6|F6SUC6_XENTR 495 LKGDTA-------VPVEEGNVDSYT------INDIVMPLPGFDVIYPKHKVAAAYEEILAADNLDIKNMR-HRVKDYSLAGAYRKIV 567
                             999666.......899*****9999......456899********************************9.4578************ PP

                    TruD 383 lrve..............................dlelsaeedeltleFsLpkGsYATvvlrEi 416
                             +r++                              + +++ + + l++eFsLp+ +YAT+ +rE+
  tr|F6SUC6|F6SUC6_XENTR 568 IRPQdvswevvsyddpkiplvqtdldklegkalpEYKTEGKYRALKMEFSLPPSTYATMAIREV 631
                             *****************************999887777777788******************96 PP

>> tr|A9JTM8|A9JTM8_XENTR  LOC100127797 protein OS=Xenopus tropicalis OX=8364 GN=pus7l PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   1.5e-07    0.0018       3      36 ..      12      44 ..      10      84 .. 0.76
   2 !  225.5   0.0   1.2e-70   1.4e-66      36     416 .]     288     689 ..     271     689 .. 0.89

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 1.5e-07
                    TruD  3 gielyvtdtegigGrlrespeDFiVeEieefsge 36
                            g  +yv+d+ g+ G++++s+ DF+V+Ei ++sg+
  tr|A9JTM8|A9JTM8_XENTR 12 GSLCYVSDHRGFFGTIKNSSADFVVTEI-DVSGQ 44
                            6779************************.44433 PP

  == domain 2  score: 225.5 bits;  conditional E-value: 1.2e-70
                    TruD  36 eeeakegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl....eikdvelevvgrarr 118
                             e ++k++ y+ ++++k n +tl++++ l+  lg+  +++++aG+KDk+A+T+Q + ++kv+pe+l+++    e k++++++++  ++
  tr|A9JTM8|A9JTM8_XENTR 288 EDTEKQDVYTGFTLQKDNLETLEAISYLSCILGVLPSDFSYAGIKDKKAITYQAMVVKKVTPERLKQIdamsEKKGMKIKNIHPVNK 374
                             3456778899********************************************************99877767************* PP

                    TruD 119 klrlGdLaGNkFeirvrdv.aeee....eaakraeeileelkekggvPNyfGvQRFGsrrp.vthlvGkaivkgdleeAveayvgkp 199
                             +l+lG+L GN+F+i+vrd+  +++      ++r+ee + ++k+kg + Ny+G QRFG+ +   +h +G a++k+++e+Av  +++  
  tr|A9JTM8|A9JTM8_XENTR 375 HLQLGHLSGNHFNIIVRDIqNHSDdlsvYVQERIEEAVYNIKTKG-FLNYYGPQRFGKGQNcQSHDIGLALLKEEMERAVTLLLTPD 460
                             *******************54444566645789999999999988.************875278****************9999876 PP

                    TruD 200 feeesedtreareavaetgdleealeelpkslryEramlkrLae...kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerg 283
                             + e  + +++a++++ et d++  l ++p+    Er++l+++ +   +++   +A  +lp+  + +++hA+ S ++N++ s R+  +
  tr|A9JTM8|A9JTM8_XENTR 461 SCE--DPVNNAKQYFIETVDAKGTLALMPHYKIRERMVLRAINRygmNNEGCVRAWLSLPHSSRIFYIHAFCSKVWNEAASYRFTLY 545
                             644..44569*********************************98888899999*******************************77 PP

                    TruD 284 lpldepveGDvvifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklp 370
                                +++v+GD+v  +e++  +++ +++vt+++ e+ +  i+    +v++p++G++ + +  + g+  +e l+++gl+   F++++  
  tr|A9JTM8|A9JTM8_XENTR 546 --GTKVVQGDLVDCNESA-NENSLVHIVTAEEEESSAYTID----QVVLPMPGYSIKYPTNKIGQWYSETLAKAGLQSCAFRVSS-L 624
                             ..579*******999666.8999999999999999998887....599**********************************998.9 PP

                    TruD 371 elsskGtrRaillrve....................dlelsaeede.......ltleFsLpkGsYATvvlrEi 416
                             +l++ G +R+il  ++                    d                +++eF L++ +YATv lrE+
  tr|A9JTM8|A9JTM8_XENTR 625 QLNVPGCYRHILKYPHdlfykltfedqakgtenkiaD--------AgvslkpvFVVEFDLDSSCYATVCLREM 689
                             9**********999999*******9888776544322........1233444589****************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (416 nodes)
Target sequences:                        24182  (11782085 residues searched)
Passed MSV filter:                       873  (0.0361012); expected 483.6 (0.02)
Passed bias filter:                      406  (0.0167893); expected 483.6 (0.02)
Passed Vit filter:                        35  (0.00144736); expected 24.2 (0.001)
Passed Fwd filter:                         2  (8.27061e-05); expected 0.2 (1e-05)
Initial search space (Z):              24182  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.33u 0.01s 00:00:00.34 Elapsed: 00:00:00.10
# Mc/sec: 49013.47
//
[ok]