# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TruD.hmm.txt # target sequence database: proteomes/Xenopus_tropicalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TruD [M=416] Accession: PF01142.17 Description: tRNA pseudouridine synthase D (TruD) Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-73 247.4 0.0 6.1e-68 230.0 0.0 2.3 2 tr|F6SUC6|F6SUC6_XENTR Pseudouridine synthase 7 OS=Xenopus t 1.7e-72 245.0 0.1 1.4e-66 225.5 0.0 2.1 2 tr|A9JTM8|A9JTM8_XENTR LOC100127797 protein OS=Xenopus tropi Domain annotation for each sequence (and alignments): >> tr|F6SUC6|F6SUC6_XENTR Pseudouridine synthase 7 OS=Xenopus tropicalis OX=8364 GN=pus7 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 8.8e-07 0.011 2 32 .. 102 132 .. 101 148 .. 0.89 2 ! 230.0 0.0 5e-72 6.1e-68 39 416 .] 240 631 .. 229 631 .. 0.93 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 8.8e-07 TruD 2 lgielyvtdtegigGrlrespeDFiVeEiee 32 +gi +v+ +eg+ G l+e++ DF+V+Ei + tr|F6SUC6|F6SUC6_XENTR 102 VGITKFVSTHEGFSGILKERYSDFVVHEIGK 132 89**************************943 PP == domain 2 score: 230.0 bits; conditional E-value: 5e-72 TruD 39 akegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl..eikdvelevvgrarrklrlG 123 + +g+y+ + + k+n dt+d+++ l++ l+i+ + ++++GtKDkrA+T+Q i++ k+++++l++l + + +l ++ ++++l+lG tr|F6SUC6|F6SUC6_XENTR 240 KARGSYCHFVLYKENKDTMDAINVLSKFLRIKPNIFSYMGTKDKRAITVQEIAVLKITAQRLAHLnkCLMNFKLGNFSYQKNPLKLG 326 567***********************************************************9996668****************** PP TruD 124 dLaGNkFeirvrdvaeeeeaakraeeileelkekggvPNyfGvQRFGsrrpvthlvGkaivkgdleeAveayvg.kpfeeesedtre 209 +L+GN+F++++r+v+ +++++ + + +l++ g + Ny+G+QRFG++ t+ vG+ai++ +++e v+ ++ +p e+e+ + tr|F6SUC6|F6SUC6_XENTR 327 ELQGNHFTVVLRNVTG---TSEQIVQAMTSLRDIG-FINYYGMQRFGTTAVPTYQVGRAILQSNWNEMVDLILKpRPGEAEKGYLVQ 409 *************943...3458888888999998.*********************************98885378889999999* PP TruD 210 areavaetgdleealeelpkslryEramlkrLae.kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerglpldepveGDvv 295 re a+t+d e+al++lp + +E ++l+ L k++ +A+ +p+n + +++h+yqSy++N+++s+R+e++ ++v+GD+v tr|F6SUC6|F6SUC6_XENTR 410 CREEWAKTKDPEAALRKLPVKRCVEGQLLRGLSMyGLKNIVSAFGIIPRNNRLMYIHSYQSYVWNNMVSKRIEEY-G-LKVVPGDLV 494 ********************************9966799**********************************99.4.48******* PP TruD 296 ifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklpelsskGtrRail 382 ++ + + v+e nv++++ +++pl+G+++ ++ +v + +e+l+ ++l+ ++ + +++++ s +G++R+i+ tr|F6SUC6|F6SUC6_XENTR 495 LKGDTA-------VPVEEGNVDSYT------INDIVMPLPGFDVIYPKHKVAAAYEEILAADNLDIKNMR-HRVKDYSLAGAYRKIV 567 999666.......899*****9999......456899********************************9.4578************ PP TruD 383 lrve..............................dlelsaeedeltleFsLpkGsYATvvlrEi 416 +r++ + +++ + + l++eFsLp+ +YAT+ +rE+ tr|F6SUC6|F6SUC6_XENTR 568 IRPQdvswevvsyddpkiplvqtdldklegkalpEYKTEGKYRALKMEFSLPPSTYATMAIREV 631 *****************************999887777777788******************96 PP >> tr|A9JTM8|A9JTM8_XENTR LOC100127797 protein OS=Xenopus tropicalis OX=8364 GN=pus7l PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 1.5e-07 0.0018 3 36 .. 12 44 .. 10 84 .. 0.76 2 ! 225.5 0.0 1.2e-70 1.4e-66 36 416 .] 288 689 .. 271 689 .. 0.89 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 1.5e-07 TruD 3 gielyvtdtegigGrlrespeDFiVeEieefsge 36 g +yv+d+ g+ G++++s+ DF+V+Ei ++sg+ tr|A9JTM8|A9JTM8_XENTR 12 GSLCYVSDHRGFFGTIKNSSADFVVTEI-DVSGQ 44 6779************************.44433 PP == domain 2 score: 225.5 bits; conditional E-value: 1.2e-70 TruD 36 eeeakegeylvlrvekrnwdtldlvrelaralgisrkrvgfaGtKDkrAvTtQlisirkvepeelekl....eikdvelevvgrarr 118 e ++k++ y+ ++++k n +tl++++ l+ lg+ +++++aG+KDk+A+T+Q + ++kv+pe+l+++ e k++++++++ ++ tr|A9JTM8|A9JTM8_XENTR 288 EDTEKQDVYTGFTLQKDNLETLEAISYLSCILGVLPSDFSYAGIKDKKAITYQAMVVKKVTPERLKQIdamsEKKGMKIKNIHPVNK 374 3456778899********************************************************99877767************* PP TruD 119 klrlGdLaGNkFeirvrdv.aeee....eaakraeeileelkekggvPNyfGvQRFGsrrp.vthlvGkaivkgdleeAveayvgkp 199 +l+lG+L GN+F+i+vrd+ +++ ++r+ee + ++k+kg + Ny+G QRFG+ + +h +G a++k+++e+Av +++ tr|A9JTM8|A9JTM8_XENTR 375 HLQLGHLSGNHFNIIVRDIqNHSDdlsvYVQERIEEAVYNIKTKG-FLNYYGPQRFGKGQNcQSHDIGLALLKEEMERAVTLLLTPD 460 *******************54444566645789999999999988.************875278****************9999876 PP TruD 200 feeesedtreareavaetgdleealeelpkslryEramlkrLae...kpkdykkAlealpknLqrlFvhAyqSylFNrvlseRlerg 283 + e + +++a++++ et d++ l ++p+ Er++l+++ + +++ +A +lp+ + +++hA+ S ++N++ s R+ + tr|A9JTM8|A9JTM8_XENTR 461 SCE--DPVNNAKQYFIETVDAKGTLALMPHYKIRERMVLRAINRygmNNEGCVRAWLSLPHSSRIFYIHAFCSKVWNEAASYRFTLY 545 644..44569*********************************98888899999*******************************77 PP TruD 284 lpldepveGDvvifaeerlpdtdrlqlvteknveevkrliergrafvtaplvGtetelaegevgeierevleeegleledFklpklp 370 +++v+GD+v +e++ +++ +++vt+++ e+ + i+ +v++p++G++ + + + g+ +e l+++gl+ F++++ tr|A9JTM8|A9JTM8_XENTR 546 --GTKVVQGDLVDCNESA-NENSLVHIVTAEEEESSAYTID----QVVLPMPGYSIKYPTNKIGQWYSETLAKAGLQSCAFRVSS-L 624 ..579*******999666.8999999999999999998887....599**********************************998.9 PP TruD 371 elsskGtrRaillrve....................dlelsaeede.......ltleFsLpkGsYATvvlrEi 416 +l++ G +R+il ++ d +++eF L++ +YATv lrE+ tr|A9JTM8|A9JTM8_XENTR 625 QLNVPGCYRHILKYPHdlfykltfedqakgtenkiaD--------AgvslkpvFVVEFDLDSSCYATVCLREM 689 9**********999999*******9888776544322........1233444589****************96 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (416 nodes) Target sequences: 24182 (11782085 residues searched) Passed MSV filter: 873 (0.0361012); expected 483.6 (0.02) Passed bias filter: 406 (0.0167893); expected 483.6 (0.02) Passed Vit filter: 35 (0.00144736); expected 24.2 (0.001) Passed Fwd filter: 2 (8.27061e-05); expected 0.2 (1e-05) Initial search space (Z): 24182 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.01s 00:00:00.34 Elapsed: 00:00:00.10 # Mc/sec: 49013.47 // [ok]