# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/UPF0020.hmm.txt
# target sequence database:        proteomes/Anolis_carolinensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       UPF0020  [M=197]
Accession:   PF01170.17
Description: Putative RNA methylase family UPF0020
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.5e-42  145.6   0.0    4.9e-42  143.9   0.0    1.8  1  tr|H9GLQ7|H9GLQ7_ANOCA  THUMP domain containing 3 OS=Anolis c
    7.8e-25   87.8   0.0    2.5e-24   86.1   0.0    1.8  1  tr|G1K8K6|G1K8K6_ANOCA  THUMP domain containing 2 OS=Anolis c
    6.9e-13   48.8   0.0    1.7e-12   47.5   0.0    1.6  1  tr|G1KAB8|G1KAB8_ANOCA  tRNA methyltransferase 11 homolog OS=
    1.3e-06   28.3   0.0    5.4e-06   26.3   0.0    2.0  1  tr|H9GPY3|H9GPY3_ANOCA  Trimethylguanosine synthase 1 OS=Anol
    1.1e-05   25.3   0.1    2.7e-05   24.0   0.1    1.8  1  tr|H9GNU1|H9GNU1_ANOCA  Methyltransferase like 5 OS=Anolis ca
    0.00036   20.3   0.0     0.0013   18.5   0.0    1.8  1  tr|R4GAD1|R4GAD1_ANOCA  HemK methyltransferase family member 
     0.0025   17.6   0.0     0.0059   16.4   0.0    1.7  1  tr|H9G6W9|H9G6W9_ANOCA  2-methoxy-6-polyprenyl-1,4-benzoquino
  ------ inclusion threshold ------
      0.013   15.2   0.4      0.066   12.9   0.4    2.0  1  tr|H9GDC5|H9GDC5_ANOCA  tRNA methyltransferase 2 homolog A OS


Domain annotation for each sequence (and alignments):
>> tr|H9GLQ7|H9GLQ7_ANOCA  THUMP domain containing 3 OS=Anolis carolinensis OX=28377 GN=THUMPD3 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.9   0.0   2.1e-45   4.9e-42       2     196 ..     305     500 ..     303     501 .. 0.92

  Alignments for each domain:
  == domain 1  score: 143.9 bits;  conditional E-value: 2.1e-45
                             SSS-SS---SS-HHHHHHHH............HHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH CS
                 UPF0020   2 gyRefngpapLketLAaalv............rlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearae 76 
                             ++++f gp++L++tLA++++            rl++ +p + ++DPmCG+G+i+IE+a  + n+++++              +++++
  tr|H9GLQ7|H9GLQ7_ANOCA 305 NITHF-GPTTLRSTLAYGMLrylcyvtkkqqrRLCDPQPADIIIDPMCGTGAIPIEGAAEWPNCYHIAG-------------DNNPQ 377
                             55555.5************944444444444448*******************************7666.............88999 PP

                             --EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT...-E CS
                 UPF0020  77 lklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgg.grl 162
                             +  + ++++++++++ r++ ++   g+ i+  q+d ++L+l++g+vdvivt++P+G+r+gskk++++LY+++l e+ r++r + gr+
  tr|H9GLQ7|H9GLQ7_ANOCA 378 AVKRTANNISSLLKQIRSKESSISAGKPIDSIQWDSCSLPLRTGSVDVIVTDMPFGKRIGSKKKNWDLYPSCLMEMGRICRPKtGRA 464
                             9999*****************************************************************************999*** PP

                             EEEEESSHHHHHCC---..ESEEEEEEETTEEEEEE CS
                 UPF0020 163 vlltsenkalekaleer..alrkvkeknvklglllk 196
                             vllt+++k+++kal+++   +rk +  +v++g+l++
  tr|H9GLQ7|H9GLQ7_ANOCA 465 VLLTQDRKCFAKALSKMghLWRKSHTIWVNVGGLHA 500
                             *****************989************9985 PP

>> tr|G1K8K6|G1K8K6_ANOCA  THUMP domain containing 2 OS=Anolis carolinensis OX=28377 GN=THUMPD2 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.1   0.0   1.1e-27   2.5e-24      10     195 ..     251     414 ..     243     416 .. 0.87

  Alignments for each domain:
  == domain 1  score: 86.1 bits;  conditional E-value: 1.1e-27
                             -SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHH CS
                 UPF0020  10 apLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNa 96 
                               L++t+A a+v la++k+g   lDP CG Gtil+Eaa+ + ++                           g D+  + +qga +N 
  tr|G1K8K6|G1K8K6_ANOCA 251 IGLRSTIAWAMVSLAEIKAGAFVLDPTCGLGTILLEAAMEWPDVN------------------------YLGTDISDAQLQGAYTNI 313
                             579*****************************************9........................79**************** PP

                             HHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT..-EEEEEESS..HHHHHCC---.E CS
                 UPF0020  97 ekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgggrlvlltsen..kalekaleer.a 180
                             ++a++ d+i++ +a +++L+l+++++dv++++ P+G++ + +k++e L + + +el+rvl+ gg lvll+s +  ++l++ +++  +
  tr|G1K8K6|G1K8K6_ANOCA 314 KAANLMDKIQLLKASVTALPLPSESIDVVLADIPFGKKFKITKDME-LLPDVFQELERVLCAGGTLVLLLSRElyMCLAHGINSGpE 399
                             *****************************************99986.6688889***************998622444554544466 PP

                             SEEEEEEETTEEEEE CS
                 UPF0020 181 lrkvkeknvklglll 195
                             +++  ++ v  ++++
  tr|G1K8K6|G1K8K6_ANOCA 400 SENHISVEVANDCTQ 414
                             666666777766665 PP

>> tr|G1KAB8|G1KAB8_ANOCA  tRNA methyltransferase 11 homolog OS=Anolis carolinensis OX=28377 GN=TRMT11 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.5   0.0   7.2e-16   1.7e-12       3     141 ..     202     333 ..     201     358 .. 0.83

  Alignments for each domain:
  == domain 1  score: 47.5 bits;  conditional E-value: 7.2e-16
                             SS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHH CS
                 UPF0020   3 yRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvv 89 
                             +R+f g++++ + LA  + +  ++kp+++ +DP+ G+G++lI  a  ga++      +  +   + + ++ r+++k +g D +    
  tr|G1KAB8|G1KAB8_ANOCA 202 KRHFIGNTSMDACLAFIMANHGRVKPNDVVFDPFIGTGGLLIASAHFGAYVF---GTDIDYSTVHGLGKASRKNQKWRGPDENI--- 282
                             79**************************************************...566778888888899999999*****876... PP

                             HHHHHHHHHTT-GGGE..EEEE--GGG--STTS---EEEE----------HHHH CS
                 UPF0020  90 qgareNaekagvgdli..efsqadaakLrlkegevdvivtnpPYGerlgskkal 141
                                r N++++g+++    +f++   + + +k +++d+i+t+pPYG+r  + ++ 
  tr|G1KAB8|G1KAB8_ANOCA 283 ---RANLRQYGLEKHYldAFVSDASRPIWRKGAQFDAIITDPPYGIREATRRTG 333
                             ...57*******986532455555566667778************986666554 PP

>> tr|H9GPY3|H9GPY3_ANOCA  Trimethylguanosine synthase 1 OS=Anolis carolinensis OX=28377 GN=TGS1 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   0.0   2.3e-09   5.4e-06      30     132 ..     784     859 ..     767     868 .. 0.87

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 2.3e-09
                             S-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG-- CS
                 UPF0020  30 epllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNaekagvgdliefsqadaakLr 116
                             + ++D +CG G+  I  al g++++                          ++D+d+  ++ a +Nae +gv+d+ief + d+ kL 
  tr|H9GPY3|H9GPY3_ANOCA 784 DIIVDAFCGVGGNSIQFALAGKRVI--------------------------AIDIDPVKIRLAHNNAEVYGVADQIEFICGDFMKLA 844
                             5677777777777777777777777..........................9*********************************** PP

                             STTS---EEEE----- CS
                 UPF0020 117 lkegevdvivtnpPYG 132
                              ++ + d++   pP+G
  tr|H9GPY3|H9GPY3_ANOCA 845 -SSLKGDIVFLSPPWG 859
                             .88899*********9 PP

>> tr|H9GNU1|H9GNU1_ANOCA  Methyltransferase like 5 OS=Anolis carolinensis OX=28377 GN=METTL5 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.0   0.1   1.2e-08   2.7e-05      79     155 ..      77     148 ..      27     186 .. 0.77

  Alignments for each domain:
  == domain 1  score: 24.0 bits;  conditional E-value: 1.2e-08
                             EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--.STTS---EEEE----------HHHHHHHHHHHHHHHHHH CS
                 UPF0020  79 lygsDldrrvvqgareNaekagvgdliefsqadaakLr.lkegevdvivtnpPYGerlgskkalekLYseflrelkrv 155
                              +g+D+d  +++   +Nae+ ++++ i++ q ++++L+ ++ + +d+++ npP+G + ++  ++     +fl+++ ++
  tr|H9GNU1|H9GNU1_ANOCA  77 CVGFDIDLDALDVFSKNAEEFELTN-IDMIQCNVCSLPdKMPKIFDTVIMNPPFGTKHNKGMDM-----AFLKTALQM 148
                             589*******************986.777888******867779***********875554443.....344444443 PP

>> tr|R4GAD1|R4GAD1_ANOCA  HemK methyltransferase family member 1 OS=Anolis carolinensis OX=28377 GN=HEMK1 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0   5.6e-07    0.0013      76     131 ..     203     262 ..     178     265 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 5.6e-07
                             H--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--....STTS---EEEE---- CS
                 UPF0020  76 elklygsDldrrvvqgareNaekagvgdliefsqadaakLr....lkegevdvivtnpPY 131
                             + k++++D+ +++v+ ++eNae+ ++++++++   ++ +      l+ g vd+i++npPY
  tr|R4GAD1|R4GAD1_ANOCA 203 HSKVIAIDKLEAAVNLTKENAERLNLQERVSVLHHEVSSSSwkylLPWGLVDTIISNPPY 262
                             56799*************************9988888776666777899*********** PP

>> tr|H9G6W9|H9G6W9_ANOCA  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Anolis carolinensis OX=283
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   2.5e-06    0.0059      26     124 ..      86     195 ..      79     228 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 2.5e-06
                             --TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SS...........HHHHHHHHHHHH--EEEEES-HHHHHHHHHHHHHTT- CS
                 UPF0020  26 wkpgepllDPmCGsGtilIEaallganiapgllrefvle...........lkaeaeeearaelklygsDldrrvvqgareNaekagv 101
                               pg++llD   G+G i+      +++    ++r++              l +e e++     +++  D++ ++++ ++++a++ g 
  tr|H9G6W9|H9G6W9_ANOCA  86 PYPGTQLLDVAGGTGDIAFRFLNSVRSHREHQVRQKLRShqnlswqeitkLYQEEEQQSLGGSHVVVCDINTEMLKVGKQKAQHLGY 172
                             55666666666777766654333333333333333333256666665432222222222244449999******************* PP

                             GGGEEEEE--GGG--STTS---E CS
                 UPF0020 102 gdliefsqadaakLrlkegevdv 124
                             ++  ++++ +a +L+ +++++d+
  tr|H9G6W9|H9G6W9_ANOCA 173 SEGLSWVVGNAEELPFNDNNFDI 195
                             ***************66667775 PP

>> tr|H9GDC5|H9GDC5_ANOCA  tRNA methyltransferase 2 homolog A OS=Anolis carolinensis OX=28377 GN=TRMT2A PE=3 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.4   2.9e-05     0.066      14      81 ..     430     498 ..     421     524 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.9e-05
                             HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SS.HHHHHHHHHHHH--EEE CS
                 UPF0020  14 etLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvle.lkaeaeeearaelklyg 81 
                             e L +a+   a++ p+++ lD  CG+Gti I  a  +++++ + l ++++e +k +a+ +  +++++y+
  tr|H9GDC5|H9GDC5_ANOCA 430 EVLYSAIQDWAQVGPETTVLDVCCGTGTIGITLAKKVKKVIGIELCQEAVEdAKVNAQLNDLNNVEFYC 498
                             6677899999*********************99999999995544333333344444444445555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (197 nodes)
Target sequences:                        18528  (9796552 residues searched)
Passed MSV filter:                       479  (0.0258528); expected 370.6 (0.02)
Passed bias filter:                      367  (0.0198079); expected 370.6 (0.02)
Passed Vit filter:                        30  (0.00161917); expected 18.5 (0.001)
Passed Fwd filter:                         8  (0.000431779); expected 0.2 (1e-05)
Initial search space (Z):              18528  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.07
# Mc/sec: 27570.30
//
[ok]