# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/UPF0020.hmm.txt
# target sequence database:        proteomes/Caenorhabditis_elegans.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       UPF0020  [M=197]
Accession:   PF01170.17
Description: Putative RNA methylase family UPF0020
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.6e-32  112.9   0.0    6.9e-32  110.9   0.0    2.0  1  tr|Q21503|Q21503_CAEEL  Uncharacterized protein OS=Caenorhabd
    4.8e-08   33.1   0.0    1.6e-07   31.4   0.0    1.8  1  tr|Q9N4H1|Q9N4H1_CAEEL  Uncharacterized protein OS=Caenorhabd
    5.3e-08   32.9   0.1    1.7e-07   31.3   0.1    1.7  1  tr|Q18511|Q18511_CAEEL  Uncharacterized protein OS=Caenorhabd
      6e-05   23.0   0.0    0.00013   21.9   0.0    1.5  1  tr|Q94013|Q94013_CAEEL  Uncharacterized protein OS=Caenorhabd
  ------ inclusion threshold ------
       0.13   12.1   0.0       0.22   11.3   0.0    1.4  1  sp|Q09522|DIM1_CAEEL    Probable dimethyladenosine transferas


Domain annotation for each sequence (and alignments):
>> tr|Q21503|Q21503_CAEEL  Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_M04B2.2 PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.9   0.0   1.7e-35   6.9e-32       8     193 ..     212     377 ..     206     380 .. 0.90

  Alignments for each domain:
  == domain 1  score: 110.9 bits;  conditional E-value: 1.7e-35
                             ---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHH CS
                 UPF0020   8 gpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgare 94 
                             gp+++++t+  ++++la++kpg+ ++D mCG+G+i+IE+a+ ++n                          + g D+ + ++ ++ +
  tr|Q21503|Q21503_CAEEL 212 GPTTMRSTMCHCMLQLADIKPGDIIVDAMCGGGSIPIEGAISWKNSL------------------------FLGGDNHEMAMSRCLQ 274
                             79*********************************************........................99************** PP

                             H..HHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT..-EEEEEESSHHHHH.CC-- CS
                 UPF0020  95 N..aekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgggrlvlltsenkalek.alee 178
                             N  a++       +f ++da++L+l+++++d++vt++P+G+++gs+ +++ LY+ +l e krvlr+ggrlvl+t+++++le+ +l++
  tr|Q21503|Q21503_CAEEL 275 NwsANSSSSRSNCDFLTWDATNLPLRDNSIDALVTDLPFGKKIGSTTDNRLLYPRLLAEWKRVLRKGGRLVLMTHDKRSLENsFLKD 361
                             *5455667778899**********9999****************************************************9724555 PP

                             -.ESEEEEEEETTEEE CS
                 UPF0020 179 r.alrkvkeknvklgl 193
                             r +++   +  v++g+
  tr|Q21503|Q21503_CAEEL 362 RsSWQTDASHVVNVGG 377
                             5677766666666665 PP

>> tr|Q9N4H1|Q9N4H1_CAEEL  Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_Y71F9AL.1 PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.4   0.0     4e-11   1.6e-07       4     142 ..     182     314 ..     180     326 .. 0.83

  Alignments for each domain:
  == domain 1  score: 31.4 bits;  conditional E-value: 4e-11
                             S-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHH CS
                 UPF0020   4 RefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvq 90 
                             R + g++++ ++L+    +la + pg+  lDP+ G+G++ + aa  ga ++            ++a+++ r   + +g   +++ ++
  tr|Q9N4H1|Q9N4H1_CAEEL 182 RCYIGNTTMDPELSFIQSNLAMISPGDIVLDPFVGTGGLILPAAEFGAFVIGTE------INYQTARAQGRSSRQGVGQRGESESIK 262
                             66788999*******************************************322......366788888899999999999999998 PP

                             HHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHH CS
                 UPF0020  91 gareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkale 142
                             +  e  ++      + + +     +   ++++d+iv++pPYG r ++ k+++
  tr|Q9N4H1|Q9N4H1_CAEEL 263 ANFEQYKSESQFLGVLIADSSKHGIWSCNAKFDAIVADPPYGVREKARKTVK 314
                             766655555544555566666666777999**************99988875 PP

>> tr|Q18511|Q18511_CAEEL  Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=C38D4.9 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.3   0.1   4.1e-11   1.7e-07      74     134 ..      68     131 ..      24     139 .. 0.85

  Alignments for each domain:
  == domain 1  score: 31.3 bits;  conditional E-value: 4.1e-11
                             HHH--.EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--..STTS---EEEE------- CS
                 UPF0020  74 raelk.lygsDldrrvvqgareNaekagvgdliefsqadaakLr..lkegevdvivtnpPYGer 134
                              +el+ + g+D+d ++++ + +N+e a+v+d+ e+ qad+ + +  l++g +dv v npP+G +
  tr|Q18511|Q18511_CAEEL  68 MYELEtVLGVDIDDEALKICSRNLETAEVQDRCELLQADILDPEsdLPRGTFDVAVINPPFGTK 131
                             2444459*********************************9998888999************86 PP

>> tr|Q94013|Q94013_CAEEL  Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_T08G11.4 PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.0   3.2e-08   0.00013      75     132 ..     411     475 ..     377     483 .. 0.79

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 3.2e-08
                             HH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--.......STTS---EEEE----- CS
                 UPF0020  75 aelklygsDldrrvvqgareNaekagvgdliefsqadaakLr.......lkegevdvivtnpPYG 132
                             + ++++++D+d+  +++areNa+ +gv++ i+f +ad+ ++        +   +vd++   pP+G
  tr|Q94013|Q94013_CAEEL 411 RGAHVIAIDMDPVRLKCARENARVYGVENYIDFICADFFDVAatwqadkKLAPKVDAVFLSPPWG 475
                             566799*********************************99988876543344899999999998 PP

>> sp|Q09522|DIM1_CAEEL  Probable dimethyladenosine transferase OS=Caenorhabditis elegans OX=6239 GN=E02H1.1 PE=3 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   5.6e-05      0.22      76     134 ..      72     128 ..      41     141 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 5.6e-05
                           H--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE------- CS
               UPF0020  76 elklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGer 134
                              +++ ++d+r+++  ++    + ++++ +++  d+ k++ +   +dv v+n+PY ++
  sp|Q09522|DIM1_CAEEL  72 AKTVIACEIDPRMIAEVKKRVMGTPLQNKLQVNGGDVMKMEWPF--FDVCVANLPYQIS 128
                           344999***********************************776..9*********765 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (197 nodes)
Target sequences:                        20008  (8229220 residues searched)
Passed MSV filter:                       526  (0.0262895); expected 400.2 (0.02)
Passed bias filter:                      400  (0.019992); expected 400.2 (0.02)
Passed Vit filter:                        44  (0.00219912); expected 20.0 (0.001)
Passed Fwd filter:                         6  (0.00029988); expected 0.2 (1e-05)
Initial search space (Z):              20008  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.06
# Mc/sec: 27019.27
//
[ok]