# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/UPF0020.hmm.txt # target sequence database: proteomes/Caenorhabditis_elegans.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: UPF0020 [M=197] Accession: PF01170.17 Description: Putative RNA methylase family UPF0020 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-32 112.9 0.0 6.9e-32 110.9 0.0 2.0 1 tr|Q21503|Q21503_CAEEL Uncharacterized protein OS=Caenorhabd 4.8e-08 33.1 0.0 1.6e-07 31.4 0.0 1.8 1 tr|Q9N4H1|Q9N4H1_CAEEL Uncharacterized protein OS=Caenorhabd 5.3e-08 32.9 0.1 1.7e-07 31.3 0.1 1.7 1 tr|Q18511|Q18511_CAEEL Uncharacterized protein OS=Caenorhabd 6e-05 23.0 0.0 0.00013 21.9 0.0 1.5 1 tr|Q94013|Q94013_CAEEL Uncharacterized protein OS=Caenorhabd ------ inclusion threshold ------ 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 sp|Q09522|DIM1_CAEEL Probable dimethyladenosine transferas Domain annotation for each sequence (and alignments): >> tr|Q21503|Q21503_CAEEL Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_M04B2.2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.9 0.0 1.7e-35 6.9e-32 8 193 .. 212 377 .. 206 380 .. 0.90 Alignments for each domain: == domain 1 score: 110.9 bits; conditional E-value: 1.7e-35 ---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHH CS UPF0020 8 gpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgare 94 gp+++++t+ ++++la++kpg+ ++D mCG+G+i+IE+a+ ++n + g D+ + ++ ++ + tr|Q21503|Q21503_CAEEL 212 GPTTMRSTMCHCMLQLADIKPGDIIVDAMCGGGSIPIEGAISWKNSL------------------------FLGGDNHEMAMSRCLQ 274 79*********************************************........................99************** PP H..HHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT..-EEEEEESSHHHHH.CC-- CS UPF0020 95 N..aekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgggrlvlltsenkalek.alee 178 N a++ +f ++da++L+l+++++d++vt++P+G+++gs+ +++ LY+ +l e krvlr+ggrlvl+t+++++le+ +l++ tr|Q21503|Q21503_CAEEL 275 NwsANSSSSRSNCDFLTWDATNLPLRDNSIDALVTDLPFGKKIGSTTDNRLLYPRLLAEWKRVLRKGGRLVLMTHDKRSLENsFLKD 361 *5455667778899**********9999****************************************************9724555 PP -.ESEEEEEEETTEEE CS UPF0020 179 r.alrkvkeknvklgl 193 r +++ + v++g+ tr|Q21503|Q21503_CAEEL 362 RsSWQTDASHVVNVGG 377 5677766666666665 PP >> tr|Q9N4H1|Q9N4H1_CAEEL Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_Y71F9AL.1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.4 0.0 4e-11 1.6e-07 4 142 .. 182 314 .. 180 326 .. 0.83 Alignments for each domain: == domain 1 score: 31.4 bits; conditional E-value: 4e-11 S-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHH CS UPF0020 4 RefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvq 90 R + g++++ ++L+ +la + pg+ lDP+ G+G++ + aa ga ++ ++a+++ r + +g +++ ++ tr|Q9N4H1|Q9N4H1_CAEEL 182 RCYIGNTTMDPELSFIQSNLAMISPGDIVLDPFVGTGGLILPAAEFGAFVIGTE------INYQTARAQGRSSRQGVGQRGESESIK 262 66788999*******************************************322......366788888899999999999999998 PP HHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHH CS UPF0020 91 gareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkale 142 + e ++ + + + + ++++d+iv++pPYG r ++ k+++ tr|Q9N4H1|Q9N4H1_CAEEL 263 ANFEQYKSESQFLGVLIADSSKHGIWSCNAKFDAIVADPPYGVREKARKTVK 314 766655555544555566666666777999**************99988875 PP >> tr|Q18511|Q18511_CAEEL Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=C38D4.9 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.3 0.1 4.1e-11 1.7e-07 74 134 .. 68 131 .. 24 139 .. 0.85 Alignments for each domain: == domain 1 score: 31.3 bits; conditional E-value: 4.1e-11 HHH--.EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--..STTS---EEEE------- CS UPF0020 74 raelk.lygsDldrrvvqgareNaekagvgdliefsqadaakLr..lkegevdvivtnpPYGer 134 +el+ + g+D+d ++++ + +N+e a+v+d+ e+ qad+ + + l++g +dv v npP+G + tr|Q18511|Q18511_CAEEL 68 MYELEtVLGVDIDDEALKICSRNLETAEVQDRCELLQADILDPEsdLPRGTFDVAVINPPFGTK 131 2444459*********************************9998888999************86 PP >> tr|Q94013|Q94013_CAEEL Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_T08G11.4 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 3.2e-08 0.00013 75 132 .. 411 475 .. 377 483 .. 0.79 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 3.2e-08 HH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--.......STTS---EEEE----- CS UPF0020 75 aelklygsDldrrvvqgareNaekagvgdliefsqadaakLr.......lkegevdvivtnpPYG 132 + ++++++D+d+ +++areNa+ +gv++ i+f +ad+ ++ + +vd++ pP+G tr|Q94013|Q94013_CAEEL 411 RGAHVIAIDMDPVRLKCARENARVYGVENYIDFICADFFDVAatwqadkKLAPKVDAVFLSPPWG 475 566799*********************************99988876543344899999999998 PP >> sp|Q09522|DIM1_CAEEL Probable dimethyladenosine transferase OS=Caenorhabditis elegans OX=6239 GN=E02H1.1 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 5.6e-05 0.22 76 134 .. 72 128 .. 41 141 .. 0.89 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 5.6e-05 H--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE------- CS UPF0020 76 elklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGer 134 +++ ++d+r+++ ++ + ++++ +++ d+ k++ + +dv v+n+PY ++ sp|Q09522|DIM1_CAEEL 72 AKTVIACEIDPRMIAEVKKRVMGTPLQNKLQVNGGDVMKMEWPF--FDVCVANLPYQIS 128 344999***********************************776..9*********765 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (197 nodes) Target sequences: 20008 (8229220 residues searched) Passed MSV filter: 526 (0.0262895); expected 400.2 (0.02) Passed bias filter: 400 (0.019992); expected 400.2 (0.02) Passed Vit filter: 44 (0.00219912); expected 20.0 (0.001) Passed Fwd filter: 6 (0.00029988); expected 0.2 (1e-05) Initial search space (Z): 20008 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.06 # Mc/sec: 27019.27 // [ok]