# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/UPF0020.hmm.txt
# target sequence database: proteomes/Macaca_mulatta.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: UPF0020 [M=197]
Accession: PF01170.17
Description: Putative RNA methylase family UPF0020
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7.4e-50 169.6 0.0 1.2e-49 168.9 0.0 1.3 1 tr|H9FSL6|H9FSL6_MACMU THUMP domain containing 3 OS=Mac
1.9e-26 93.2 0.0 6.6e-26 91.5 0.0 1.9 1 tr|F7H715|F7H715_MACMU THUMP domain containing 2 OS=Mac
7.3e-12 45.6 0.0 1.6e-11 44.5 0.0 1.5 1 tr|F6ZLG8|F6ZLG8_MACMU tRNA guanosine-2'-O-methyltransf
9.3e-08 32.2 0.2 9.1e-07 29.0 0.2 2.1 1 tr|F6V6X0|F6V6X0_MACMU Methyltransferase like 5 OS=Maca
1.6e-05 25.0 0.0 5e-05 23.3 0.0 1.8 1 tr|F7G2A0|F7G2A0_MACMU Trimethylguanosine synthase 1 OS
0.00015 21.8 0.0 0.0003 20.8 0.0 1.4 1 tr|A0A1D5RD03|A0A1D5RD03_MACMU HemK methyltransferase family me
------ inclusion threshold ------
0.16 11.9 0.4 3 7.7 0.4 2.2 1 tr|H9FSY6|H9FSY6_MACMU tRNA (Uracil-5-)-methyltransfera
0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 tr|A0A1D5Q9E6|A0A1D5Q9E6_MACMU Uncharacterized protein OS=Macac
Domain annotation for each sequence (and alignments):
>> tr|H9FSL6|H9FSL6_MACMU THUMP domain containing 3 OS=Macaca mulatta OX=9544 GN=THUMPD3 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 168.9 0.0 4.6e-53 1.2e-49 2 195 .. 294 476 .. 292 478 .. 0.95
Alignments for each domain:
== domain 1 score: 168.9 bits; conditional E-value: 4.6e-53
SSS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHH CS
UPF0020 2 gyRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrv 88
++++f gp++L++tLA++++rl++ p + ++DPmCG+G+i+IE+a+ ++++ +++ ++++ + ++++++++++
tr|H9FSL6|H9FSL6_MACMU 294 NITHF-GPTTLRSTLAYGMLRLCDPLPYDIIVDPMCGTGAIPIEGATEWTDCFHIAG-------------DNNPLAVNRAANNIASL 366
55555.5**********************************************7665.............8999999********** PP
HHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT...-EEEEEESSHHHHH CS
UPF0020 89 vqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgg.grlvlltsenkalek 174
+++++ + k +g i+++q+d+++L+l++g+vd+ivt++P+G+r+gskk++++LY+++lre++rv+ gr+vllt+++k+++k
tr|H9FSL6|H9FSL6_MACMU 367 LTKSQIKEGKPSWGLPIDAVQWDICNLPLRTGSVDIIVTDLPFGKRMGSKKRNWNLYPACLREMSRVCTPTtGRAVLLTQDTKCFTK 453
********************************************************************9988*************** PP
CC---..ESEEEEEEETTEEEEE CS
UPF0020 175 aleer..alrkvkeknvklglll 195
al+ + +rkv ++v++g+l+
tr|H9FSL6|H9FSL6_MACMU 454 ALSGMrhVWRKVDTVWVNVGGLR 476
***99899************987 PP
>> tr|F7H715|F7H715_MACMU THUMP domain containing 2 OS=Macaca mulatta OX=9544 GN=THUMPD2 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 91.5 0.0 2.5e-29 6.6e-26 4 170 .. 274 412 .. 272 433 .. 0.92
Alignments for each domain:
== domain 1 score: 91.5 bits; conditional E-value: 2.5e-29
S-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHH CS
UPF0020 4 RefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvq 90
R + + a L++t+A a+ la++k+g lDPmCG Gtil+Eaa + +++ +g+D + +
tr|F7H715|F7H715_MACMU 274 RAYIKTAGLRSTIAWAMASLADIKAGAFVLDPMCGLGTILLEAAKEWPDVY------------------------YVGADVSDSQLL 336
788899*********************************************........................79********** PP
HHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT..-EEEEEESSH CS
UPF0020 91 gareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgggrlvlltsenk 170
g+ +N+++ag++d+ie+ + + +L+l++++vd+i+++ P+G++ + k+++ ++l+e++rvl+ gg +vll+se+
tr|F7H715|F7H715_MACMU 337 GTWDNLKAAGLEDKIELLKVSVIELPLPSESVDIIISDIPFGKKFKLGKDIK----SILQEMERVLHVGGTIVLLLSEDH 412
**********************************************999986....5799999999999*****999864 PP
>> tr|F6ZLG8|F6ZLG8_MACMU tRNA guanosine-2'-O-methyltransferase TRM11 homolog OS=Macaca mulatta OX=9544 GN=TRMT11 PE=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 44.5 0.0 6e-15 1.6e-11 3 140 .. 190 320 .. 189 325 .. 0.85
Alignments for each domain:
== domain 1 score: 44.5 bits; conditional E-value: 6e-15
SS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHH CS
UPF0020 3 yRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvv 89
+R+f g++++ + L+ + + ++k+++ +DP+ G+G++lI a ga+++ + ++ + + +++r+++k +g D +
tr|F6ZLG8|F6ZLG8_MACMU 190 KRHFIGNTSMDAGLSFIMANHGKVKENDIVFDPFVGTGGLLIASAHFGAYVY---GTDIDYNTVHGLGKATRKNQKWRGPDENI--- 270
79**************************************************...56678888888999999999******876... PP
HHHHHHHHHTT-GGG.EEEEE--GGG--.STTS---EEEE----------HHH CS
UPF0020 90 qgareNaekagvgdl.iefsqadaakLr.lkegevdvivtnpPYGerlgskka 140
r N++++g+++ ++ + da k +k +d+i+t+pPYG+r ++ ++
tr|F6ZLG8|F6ZLG8_MACMU 271 ---RANLRQYGLEKYyLDVLVSDASKPSwRKGTYFDAIITDPPYGIRESTRRT 320
...5799999999852455666666655435559*************888775 PP
>> tr|F6V6X0|F6V6X0_MACMU Methyltransferase like 5 OS=Macaca mulatta OX=9544 GN=METTL5 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 29.0 0.2 3.4e-10 9.1e-07 13 142 .. 32 140 .. 25 174 .. 0.77
Alignments for each domain:
== domain 1 score: 29.0 bits; conditional E-value: 3.4e-10
-HHHHHHHHHHTT--....TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHH CS
UPF0020 13 ketLAaalvrlagwk....pgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareN 95
++ +Aa++++ + ++++++D CG G + I a+lga +g+D+d+ +++ ++N
tr|F6V6X0|F6V6X0_MACMU 32 RPHIAACMLYTIHNTyddiENKVIADLGCGCGVLSIGTAMLGAGLC-------------------------VGFDIDEDALEIFNRN 93
6667777766554441111445788888888888888888888777.........................8*************** PP
HHHTT-GGGEEEEE--GGG--.STTS---EEEE----------HHHHH CS
UPF0020 96 aekagvgdliefsqadaakLr.lkegevdvivtnpPYGerlgskkale 142
e+ ++++ i+++q d++ L ++++++d+++ npP+G + ++ ++
tr|F6V6X0|F6V6X0_MACMU 94 VEEFELTN-IDMVQCDVCLLSnRMSKSFDTVIMNPPFGTKNNKGTDMA 140
*****986.788888*****998999************9877666554 PP
>> tr|F7G2A0|F7G2A0_MACMU Trimethylguanosine synthase 1 OS=Macaca mulatta OX=9544 GN=TGS1 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 23.3 0.0 1.9e-08 5e-05 48 132 .. 712 769 .. 678 817 .. 0.83
Alignments for each domain:
== domain 1 score: 23.3 bits; conditional E-value: 1.9e-08
HHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----- CS
UPF0020 48 llganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYG 132
l g +++++D+d+ ++ ar+Nae +g++d+ief + d+ L + + dv+ pP+G
tr|F7G2A0|F7G2A0_MACMU 712 LTGM--------------------------RVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLLA-ACLKADVVFLSPPWG 769
4444..........................4669********************************999.77789*********9 PP
>> tr|A0A1D5RD03|A0A1D5RD03_MACMU HemK methyltransferase family member 1 OS=Macaca mulatta OX=9544 GN=HEMK1 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.8 0.0 1.1e-07 0.0003 77 131 .. 227 285 .. 217 294 .. 0.90
Alignments for each domain:
== domain 1 score: 20.8 bits; conditional E-value: 1.1e-07
--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--....STTS---EEEE---- CS
UPF0020 77 lklygsDldrrvvqgareNaekagvgdliefsqadaakLr....lkegevdvivtnpPY 131
+++++D+ ++++ + eNa++ +++d+i + +d+++ r l+ g vd++++npPY
tr|A0A1D5RD03|A0A1D5RD03_MACMU 227 SRVIAVDKGEAAISLTHENAQRLQLQDRIWIIHLDMTSERswthLPWGPVDLVISNPPY 285
4599********************************998877778899*********** PP
>> tr|H9FSY6|H9FSY6_MACMU tRNA (Uracil-5-)-methyltransferase homolog A OS=Macaca mulatta OX=9544 GN=TRMT2A PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 7.7 0.4 0.0011 3 14 101 .. 418 479 .. 409 512 .. 0.66
Alignments for each domain:
== domain 1 score: 7.7 bits; conditional E-value: 0.0011
HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHHHHTT CS
UPF0020 14 etLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNaekag 100
e L ++ a++++g++ lD CG+Gti + a +++++ g++l +++v+ ar Na+ +
tr|H9FSY6|H9FSY6_MACMU 418 EVLYTVIQDWAQLDAGSTVLDVCCGTGTIGLALARKVKRVI--------------------------GVELCPEAVEDARVNAQDNE 478
55556667778889999999999999999776665555555..........................55555555555555555544 PP
- CS
UPF0020 101 v 101
+
tr|H9FSY6|H9FSY6_MACMU 479 L 479
4 PP
>> tr|A0A1D5Q9E6|A0A1D5Q9E6_MACMU Uncharacterized protein OS=Macaca mulatta OX=9544 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.7 0.0 0.00014 0.37 98 136 .. 76 104 .. 50 115 .. 0.67
Alignments for each domain:
== domain 1 score: 10.7 bits; conditional E-value: 0.00014
HTT-GGGEEEEE--GGG--STTS---EEEE--------- CS
UPF0020 98 kagvgdliefsqadaakLrlkegevdvivtnpPYGerlg 136
+ ++ ++ +++ +++d+++ npP+G + +
tr|A0A1D5Q9E6|A0A1D5Q9E6_MACMU 76 EFEL--------TNIDMVQ--CDSFDTVIMNPPFGTKNN 104
3333........3333333..459***********8755 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (197 nodes)
Target sequences: 21211 (10888574 residues searched)
Passed MSV filter: 560 (0.0264014); expected 424.2 (0.02)
Passed bias filter: 442 (0.0208382); expected 424.2 (0.02)
Passed Vit filter: 45 (0.00212154); expected 21.2 (0.001)
Passed Fwd filter: 8 (0.000377163); expected 0.2 (1e-05)
Initial search space (Z): 21211 [actual number of targets]
Domain search space (domZ): 8 [number of targets reported over threshold]
# CPU time: 0.20u 0.01s 00:00:00.21 Elapsed: 00:00:00.09
# Mc/sec: 23833.88
//
[ok]