# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/UPF0020.hmm.txt
# target sequence database: proteomes/Ornithorhynchus_anatinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: UPF0020 [M=197]
Accession: PF01170.17
Description: Putative RNA methylase family UPF0020
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
3.4e-46 157.7 0.0 5e-46 157.1 0.0 1.2 1 tr|F6WCE9|F6WCE9_ORNAN THUMP domain containing 3 OS=Ornithor
1.8e-14 54.2 0.9 1.5e-13 51.2 0.9 2.2 1 tr|F6ZAJ2|F6ZAJ2_ORNAN Uncharacterized protein OS=Ornithorhy
1.8e-10 41.1 0.0 3.9e-10 40.0 0.0 1.5 1 tr|F7AMQ3|F7AMQ3_ORNAN tRNA methyltransferase 11 homolog OS=
8.9e-08 32.3 0.1 7.9e-07 29.2 0.1 2.1 1 tr|F6R9A4|F6R9A4_ORNAN Methyltransferase like 5 OS=Ornithorh
2.2e-05 24.5 0.0 8.6e-05 22.6 0.0 1.8 1 tr|F6YXL2|F6YXL2_ORNAN Trimethylguanosine synthase 1 OS=Orni
0.0078 16.2 0.0 0.018 15.0 0.0 1.7 2 tr|F7CZD8|F7CZD8_ORNAN 2-methoxy-6-polyprenyl-1,4-benzoquino
------ inclusion threshold ------
0.015 15.3 0.0 0.37 10.7 0.0 2.2 2 tr|F7DN36|F7DN36_ORNAN Uncharacterized protein OS=Ornithorhy
Domain annotation for each sequence (and alignments):
>> tr|F6WCE9|F6WCE9_ORNAN THUMP domain containing 3 OS=Ornithorhynchus anatinus OX=9258 GN=THUMPD3 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 157.1 0.0 1.6e-49 5e-46 7 196 .. 218 397 .. 212 398 .. 0.96
Alignments for each domain:
== domain 1 score: 157.1 bits; conditional E-value: 1.6e-49
S---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHH CS
UPF0020 7 ngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgar 93
+gp++L++tLA++++rl+ + g++++DPmCGsG+i IE+ + n+++++ ++++ + ++s ++++++++
tr|F6WCE9|F6WCE9_ORNAN 218 FGPTTLRSTLAYGMLRLCSPQLGDVIVDPMCGSGAISIEGICEWPNCYHIAG-------------DNNPLAVKRASSNIWSLMTRNS 291
67**********************************************7666.............88899999************** PP
HHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT...-EEEEEESSHHHHHCC--- CS
UPF0020 94 eNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgg.grlvlltsenkalekaleer 179
++ +k ++g ++ q+d+++L+l++++vd+iv+++P+G+r+gs k++++LY+ +l+e++rv++ g gr+vllt+++k++ kal+++
tr|F6WCE9|F6WCE9_ORNAN 292 TKERKPTIGLPVDSIQWDICNLPLRTSSVDIIVSDMPFGKRIGSRKKNWDLYPFCLQEMSRVCKPGtGRAVLLTQDRKCFIKALSKM 378
***********************999**************************************999******************** PP
..ESEEEEEEETTEEEEEE CS
UPF0020 180 ..alrkvkeknvklglllk 196
+rkv+ +v++g+l++
tr|F6WCE9|F6WCE9_ORNAN 379 cdVWRKVQTAWVNIGGLHA 397
*9*************9985 PP
>> tr|F6ZAJ2|F6ZAJ2_ORNAN Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 51.2 0.9 4.8e-17 1.5e-13 4 109 .. 270 351 .. 268 358 .. 0.94
Alignments for each domain:
== domain 1 score: 51.2 bits; conditional E-value: 4.8e-17
S-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHH CS
UPF0020 4 RefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvq 90
R + + a L++t+A a+ la++++g+ lDPmCG Gtil+Eaa + ++ g D+ ++ +q
tr|F6ZAJ2|F6ZAJ2_ORNAN 270 RTYIKTAGLRSTIAWAMASLAEINAGSLVLDPMCGLGTILLEAAKEWPDAN------------------------YLGTDISNSQLQ 332
888999******************************************999........................79********** PP
HHHHHHHHTT-GGGEEEEE CS
UPF0020 91 gareNaekagvgdliefsq 109
ar+N ++ag+ d+ie+ +
tr|F6ZAJ2|F6ZAJ2_ORNAN 333 VARDNVNAAGLMDKIELLK 351
**************99765 PP
>> tr|F7AMQ3|F7AMQ3_ORNAN tRNA methyltransferase 11 homolog OS=Ornithorhynchus anatinus OX=9258 GN=TRMT11 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 40.0 0.0 1.3e-13 3.9e-10 3 140 .. 191 321 .. 190 333 .. 0.86
Alignments for each domain:
== domain 1 score: 40.0 bits; conditional E-value: 1.3e-13
SS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHH CS
UPF0020 3 yRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvv 89
+R+f g++++ + LA + + ++k++++ +DP+ G+G++l+ a ga++ + ++ + + +++r+++k +g D +
tr|F7AMQ3|F7AMQ3_ORNAN 191 KRHFIGNTSMDAGLAFIMTNHGRVKENDVVFDPFVGTGGLLVASAHFGAYVC---GTDIDYNTVHGLGKATRRNQKWRGPDENI--- 271
79**************************************************...5667888888999999999*******876... PP
HHHHHHHHHTT-GGG.EEEEE--GGG--.STTS---EEEE----------HHH CS
UPF0020 90 qgareNaekagvgdl.iefsqadaakLr.lkegevdvivtnpPYGerlgskka 140
r N++++g+++ ++ + da k +k +++i+t+pPYG+r ++ k+
tr|F7AMQ3|F7AMQ3_ORNAN 272 ---RANLRQYGLEKYyLDVLVSDASKPSwRKGMFFNTILTDPPYGIRESTRKT 321
...57999999998624566667766664355589************887765 PP
>> tr|F6R9A4|F6R9A4_ORNAN Methyltransferase like 5 OS=Ornithorhynchus anatinus OX=9258 GN=METTL5 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 29.2 0.1 2.6e-10 7.9e-07 28 139 .. 51 137 .. 25 175 .. 0.75
Alignments for each domain:
== domain 1 score: 29.2 bits; conditional E-value: 2.6e-10
TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG CS
UPF0020 28 pgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNaekagvgdliefsqadaak 114
++++ +D CG G + I a+lga +g+D+d+ +++ +N e+ ++++ i++ q ++++
tr|F6R9A4|F6R9A4_ORNAN 51 EDKVVADLGCGCGVLSIGSAMLGAGLC-------------------------VGFDIDEDALEIFSRNVEEFELTN-IDMIQSNVCS 111
455666666777777777777777666.........................8********************986.788888**** PP
--.STTS---EEEE----------HH CS
UPF0020 115 Lr.lkegevdvivtnpPYGerlgskk 139
L+ ++++++d+++ npP+G + ++
tr|F6R9A4|F6R9A4_ORNAN 112 LPdRMSKSFDTVIMNPPFGTKHNKGM 137
**99999************8766554 PP
>> tr|F6YXL2|F6YXL2_ORNAN Trimethylguanosine synthase 1 OS=Ornithorhynchus anatinus OX=9258 GN=TGS1 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.6 0.0 2.8e-08 8.6e-05 33 132 .. 620 692 .. 615 694 .. 0.86
Alignments for each domain:
== domain 1 score: 22.6 bits; conditional E-value: 2.8e-08
EETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STT CS
UPF0020 33 lDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNaekagvgdliefsqadaakLrlke 119
+D +CG G+ +I al g++++ ++D+d+ ++ ar+Na+ +gv+d+ e+ + d+ L ++
tr|F6YXL2|F6YXL2_ORNAN 620 VDAFCGVGGNAIQFALAGKRVI--------------------------AIDIDPVKIDLARNNAQVYGVADRLELICGDFLLLA-PN 679
5666666666666666666666..........................9********************************999.99 PP
S---EEEE----- CS
UPF0020 120 gevdvivtnpPYG 132
+ dv+ pP+G
tr|F6YXL2|F6YXL2_ORNAN 680 LKADVVFLSPPWG 692
9***********9 PP
>> tr|F7CZD8|F7CZD8_ORNAN 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Ornithorhynchus anatinus O
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.0 0.0 5.7e-06 0.018 26 124 .. 104 213 .. 97 243 .. 0.66
2 ? -4.0 0.0 3.8 1.2e+04 167 186 .. 293 312 .. 291 318 .. 0.77
Alignments for each domain:
== domain 1 score: 15.0 bits; conditional E-value: 5.7e-06
--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SS........HHHHHHHHHH.......HH--EEEEES-HHHHHHHHHHHH CS
UPF0020 26 wkpgepllDPmCGsGtilIEaallganiapgllrefvle........lkaeaeeear.......aelklygsDldrrvvqgareNae 97
+pg++llD G+G i+ ++ ++ re+ + ++ + +++ D+++++++ ++e+a+
tr|F7CZD8|F7CZD8_ORNAN 104 PHPGTQLLDVAGGTGDIAFRFINYIRSQQRQQQREKLKAqqnlswaeI----AKSYQgvahdplGGSQVVVCDINKEMLKVGKEKAQ 186
556666666666666665443333333332333332222554433332....22222322233334458999*************** PP
HTT-GGGEEEEE--GGG--STTS---E CS
UPF0020 98 kagvgdliefsqadaakLrlkegevdv 124
g g+ ++++ da +L+ +++++dv
tr|F7CZD8|F7CZD8_ORNAN 187 TLGYGKGLAWVVGDAEELPFDDDKFDV 213
*******************88778886 PP
== domain 2 score: -4.0 bits; conditional E-value: 3.8
ESSHHHHHCC---ESEEEEE CS
UPF0020 167 senkalekaleeralrkvke 186
++++++++++e++ +rkv+
tr|F7CZD8|F7CZD8_ORNAN 293 PAQEEFKEMIEDAGFRKVTY 312
67788999999999998875 PP
>> tr|F7DN36|F7DN36_ORNAN Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.7 0.0 0.00012 0.37 92 154 .. 150 215 .. 148 241 .. 0.86
2 ? 2.1 0.0 0.054 1.7e+02 113 154 .. 337 381 .. 318 409 .. 0.74
Alignments for each domain:
== domain 1 score: 10.7 bits; conditional E-value: 0.00012
HHHHHHHTT-GGGEEEEE--GGG--...STTS---EEEE----------HHHHHHHHHHHHHHHHH CS
UPF0020 92 areNaekagvgdliefsqadaakLr...lkegevdvivtnpPYGerlgskkalekLYseflrelkr 154
ar+ ++ + +++++++++++ ++ ++++ + +i+++ P+ e+l + +++++LY++++++l +
tr|F7DN36|F7DN36_ORNAN 150 ARKEVKSWEEQEQWDVEDMKVSGVHwgyEETKTFLAILGEAPFSEKLRTCHQNRHLYRAIAERLRE 215
667777777788889999999999999988889***************************999877 PP
== domain 2 score: 2.1 bits; conditional E-value: 0.054
GG--...STTS---EEEE----------HHHHHHHHHHHHHHHHH CS
UPF0020 113 akLr...lkegevdvivtnpPYGerlgskkalekLYseflrelkr 154
a ++ ++++ + i+++ P+ e+l + +++ + Y++++++l
tr|F7DN36|F7DN36_ORNAN 337 AGVHwgyEETKTFLGILGEAPFSEKLRTCHQNSQVYRAIAERLRA 381
55555555566788899*********************9988765 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (197 nodes)
Target sequences: 21677 (8259262 residues searched)
Passed MSV filter: 554 (0.025557); expected 433.5 (0.02)
Passed bias filter: 452 (0.0208516); expected 433.5 (0.02)
Passed Vit filter: 39 (0.00179914); expected 21.7 (0.001)
Passed Fwd filter: 7 (0.000322923); expected 0.2 (1e-05)
Initial search space (Z): 21677 [actual number of targets]
Domain search space (domZ): 7 [number of targets reported over threshold]
# CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.06
# Mc/sec: 27117.91
//
[ok]