# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/UPF0020.hmm.txt
# target sequence database:        proteomes/Thermococcus_kodakarensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       UPF0020  [M=197]
Accession:   PF01170.17
Description: Putative RNA methylase family UPF0020
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.4e-40  136.2   0.0      1e-39  133.4   0.0    2.0  1  tr|Q5JEM0|Q5JEM0_THEKO  Predicted N6-adenine-specific DNA met
      2e-27   93.3   0.0    1.6e-26   90.3   0.0    2.0  1  tr|Q5JID5|Q5JID5_THEKO  N2, N2-dimethylguanosine tRNA methylt
    1.7e-14   51.1   0.0    7.6e-12   42.4   0.0    3.5  2  tr|Q5JEC3|Q5JEC3_THEKO  Predicted DNA methylase OS=Thermococc
    1.4e-11   41.6   0.1    2.2e-11   40.9   0.1    1.4  1  tr|Q5JDP7|Q5JDP7_THEKO  Predicted DNA methylase OS=Thermococc
    2.5e-05   21.2   0.0    0.00036   17.4   0.0    2.5  2  tr|Q5JE97|Q5JE97_THEKO  Predicted endonuclease-methyltransfer
    9.1e-05   19.3   0.0    0.00014   18.7   0.0    1.3  1  tr|Q5JDR0|Q5JDR0_THEKO  SAM-dependent methyltransferase, UPF0
     0.0003   17.6   0.0    0.00074   16.3   0.0    1.6  1  tr|Q5JG68|Q5JG68_THEKO  SAM-dependent methyltransferase, UbiE
     0.0004   17.2   0.1      0.012   12.4   0.0    2.7  2  tr|Q5JJ78|Q5JJ78_THEKO  Probable tRNA/rRNA methyltransferase 
     0.0022   14.8   0.0     0.0054   13.5   0.0    1.6  1  tr|Q5JHF7|Q5JHF7_THEKO  23S rRNA (Uracil-5-)-methyltransferas
      0.003   14.3   0.0     0.0043   13.9   0.0    1.4  1  tr|Q5JJF0|Q5JJF0_THEKO  Ribosomal RNA small subunit methyltra
     0.0031   14.3   0.0     0.0051   13.6   0.0    1.3  1  tr|Q5JIX8|Q5JIX8_THEKO  N5-glutamine methyltransferase, HemK 
     0.0071   13.1   0.0      0.012   12.3   0.0    1.4  1  tr|Q5JH73|Q5JH73_THEKO  Uncharacterized protein OS=Thermococc
  ------ inclusion threshold ------
       0.02   11.7   0.0      0.046   10.5   0.0    1.5  2  tr|Q5JHQ2|Q5JHQ2_THEKO  SAM-dependent methyltransferase, UbiE
      0.027   11.3   0.0      0.064   10.0   0.0    1.5  2  tr|Q5JEE1|Q5JEE1_THEKO  Protein-L-isoaspartate O-methyltransf
       0.03   11.1   0.0      0.051   10.3   0.0    1.4  1  tr|Q5JE68|Q5JE68_THEKO  23S rRNA (Uracil-5-)-methyltransferas


Domain annotation for each sequence (and alignments):
>> tr|Q5JEM0|Q5JEM0_THEKO  Predicted N6-adenine-specific DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  133.4   0.0   6.6e-42     1e-39       1     195 [.     191     358 ..     191     360 .. 0.96

  Alignments for each domain:
  == domain 1  score: 133.4 bits;  conditional E-value: 6.6e-42
                             -SSS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HH CS
                 UPF0020   1 RgyRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrr 87 
                             R +R++++pa+Lk+++A al++la+ + g +++DP+CGsGtilIE al g +                          ++g+++ r+
  tr|Q5JEM0|Q5JEM0_THEKO 191 RPWRVYDHPAHLKASIANALIELAEPN-GGSFIDPFCGSGTILIELALRGYKGR------------------------IIGLEKYRK 252
                             78***********************97.56899*****************9999........................9******** PP

                             HHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT..-EEEEEESSHHHHH CS
                 UPF0020  88 vvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgggrlvlltsenkalek 174
                             +++ga+ Na +agv d+ief q da+kL +  ++vd  v+n+PYG ++g+k ++ +LY +f +el++vl++  r v++t+e+ka+e+
  tr|Q5JEM0|Q5JEM0_THEKO 253 HIRGAEMNALSAGVLDKIEFIQGDATKLSQYVESVDFAVSNLPYGLKIGRKSMIPRLYMAFFSELSKVLEK--RGVFITTEKKAIER 337
                             *****************************8889**************************************..************** PP

                             CC---ESEEEEEEETTEEEEE CS
                 UPF0020 175 aleeralrkvkeknvklglll 195
                             a+ ++ ++ ++ + + +g+l+
  tr|Q5JEM0|Q5JEM0_THEKO 338 AILDNGFKIKHHRLIGHGGLM 358
                             *******99999988888876 PP

>> tr|Q5JID5|Q5JID5_THEKO  N2, N2-dimethylguanosine tRNA methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.3   0.0   1.1e-28   1.6e-26       3     171 ..     156     298 ..     154     324 .. 0.91

  Alignments for each domain:
  == domain 1  score: 90.3 bits;  conditional E-value: 1.1e-28
                             SS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHH CS
                 UPF0020   3 yRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvv 89 
                              R+f+ p +L +++++alv+l+++  ++ +lDP+ G G+ilIEa+llg +++                          g+D+ +++v
  tr|Q5JID5|Q5JID5_THEKO 156 HRPFFRPISLHPRVSRALVNLTKA--TREILDPFMGAGGILIEAGLLGLRVY--------------------------GVDIRPEMV 214
                             79*******************965..678*********************99..........................********* PP

                             HHHHHHHHHTT-GGGEEEEE--GGG--..STTS---EEEE----------HHHH.HHHHHHHHHHHHHH-TT..-EEEEEESSHH CS
                 UPF0020  90 qgareNaekagvgdliefsqadaakLr..lkegevdvivtnpPYGerlgskkal.ekLYseflrelkrvlrgggrlvlltsenka 171
                             +ga++N++++gv d  +++  da+ L+   +++++++++t+pPYG + + ++++ ++LY++ lr++ +vl+ ggrl+++++++ +
  tr|Q5JID5|Q5JID5_THEKO 215 EGAETNLKHYGVRDY-TLKLGDATRLEdlFPDKKFEAVATDPPYGTAATLAGRKrDELYRKALRSIYNVLEDGGRLAIAFPTDFN 298
                             ************996.688899****9987888**************999988879************************98755 PP

>> tr|Q5JEC3|Q5JEC3_THEKO  Predicted DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.29        44     140     163 ..      87     110 ..      84     121 .. 0.84
   2 !   42.4   0.0     5e-14   7.6e-12      12     170 ..     175     321 ..     166     324 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.29
                             HHHHHHHHHHHHHHHH-TT..-EE CS
                 UPF0020 140 alekLYseflrelkrvlrgggrlv 163
                             + +kL++++++e+k++++++g + 
  tr|Q5JEC3|Q5JEC3_THEKO  87 SDWKLWRKLGSEIKKRFKEEGSAK 110
                             5699***************98765 PP

  == domain 2  score: 42.4 bits;  conditional E-value: 5e-14
                             S-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHH.. CS
                 UPF0020  12 LketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNa.. 96 
                             + ++LA+ +v+l+++++g ++lDP+CG Gt+  E  l+g +++                          gsD d+  ++ a++N+  
  tr|Q5JEC3|Q5JEC3_THEKO 175 IPPRLARIMVNLTEVRKG-SFLDPFCGIGTVVQEFVLQGLTAY--------------------------GSDRDEGQIRDAKKNLtw 234
                             6789***********998.699******************999..........................***************944 PP

                             ..HHTT-GGGEEEEE--GGG--.STTS---EEEE----..........------HHHHHHHHHHHHHHHHHH-TT..-EEEEEESSH CS
                 UPF0020  97 ..ekagvgdliefsqadaakLr.lkegevdvivtnpPY..........GerlgskkalekLYseflrelkrvlrgggrlvlltsenk 170
                               ++ +++++ ++++ da+kL+   ++ +d+ivt+p            Ge+++ +++l+++Y ++ ++++ vl+++g+ v++++++k
  tr|Q5JEC3|Q5JEC3_THEKO 235 lrKEFRLKNSAHLEVCDARKLKkCFRQRFDAIVTEPYLgkplkrhpsrGEAIKLANELDRFYYSVFESFADVLKRNGKVVFVFPAYK 321
                             4457889999************755669******975522223333335566666788999*********************99876 PP

>> tr|Q5JDP7|Q5JDP7_THEKO  Predicted DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.9   0.1   1.5e-13   2.2e-11      78     138 ..      72     129 ..      43     133 .. 0.92

  Alignments for each domain:
  == domain 1  score: 40.9 bits;  conditional E-value: 1.5e-13
                             -EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------H CS
                 UPF0020  78 klygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgsk 138
                             ++y+++ d+++++ areNa++ gv+d+ief++ad+ ++     +vd+++ npP+G  ++++
  tr|Q5JDP7|Q5JDP7_THEKO  72 NVYAVERDKEALEIARENARSLGVEDKIEFVNADVSEFS-V--NVDTVIMNPPFGSQVKHA 129
                             489*********************************999.4..5***********998765 PP

>> tr|Q5JE97|Q5JE97_THEKO  Predicted endonuclease-methyltransferase fusion protein OS=Thermococcus kodakarensis (strain 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   2.4e-06   0.00036      27      96 ..     385     451 ..     371     472 .. 0.72
   2 ?    0.3   0.0      0.39        59     115     131 ..     582     596 ..     561     613 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 2.4e-06
                             -TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SS.HHHHHHHHHHHH--EEEEES-HHHHHHHHHHH CS
                 UPF0020  27 kpgepllDPmCGsGtilIEaallganiapgllrefvle.lkaeaeeearaelklygsDldrrvvqgareNa 96 
                             +p+++ lDP CGsGt+l+ a     ++a     ++++  + a+++  +  + +++g+Dl++ +v +ar N 
  tr|Q5JE97|Q5JE97_THEKO 385 NPEKRVLDPACGSGTFLVLAI----KRAKEWGLRHWGTsADAQLRLLESITSNIVGIDLNPLAVLAARGNY 451
                             5899*************8554....4443333445554255555566667777***********9999985 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.39
                             --STTS---EEEE---- CS
                 UPF0020 115 LrlkegevdvivtnpPY 131
                             L  + g++d +++npP+
  tr|Q5JE97|Q5JE97_THEKO 582 L--TIGNFDFVIGNPPW 596
                             3..45689********9 PP

>> tr|Q5JDR0|Q5JDR0_THEKO  SAM-dependent methyltransferase, UPF0020 family OS=Thermococcus kodakarensis (strain ATCC BAA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   9.4e-07   0.00014      68     153 ..     141     229 ..     103     238 .. 0.79

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 9.4e-07
                             HHHHHHHHH--EEEEES-HHHHHHHHHH..HHHTT-GGGEEEEE--GGG--..STTS---EEEE----------HHHHHHHHHHHHH CS
                 UPF0020  68 eaeeearaelklygsDldrrvvqgareN..aekagvgdliefsqadaakLr..lkegevdvivtnpPYGerlgskkalekLYseflr 150
                             +a e+ ++ + ++ +++d++v++ ar N   ++   g++i++ q da ++    k++++dvi+ +pP   +l  +   e++Y+e+ r
  tr|Q5JDR0|Q5JDR0_THEKO 141 TAIEASKRGAYVITIEKDPNVIEIARINpwSRELFTGGKIQVIQGDAFEVVkkFKQASFDVIIHDPPR-FSLAGHLYSEEFYRELFR 226
                             55566666777999**************55577889***********9998666677**********3.344445555888888877 PP

                             HHH CS
                 UPF0020 151 elk 153
                              lk
  tr|Q5JDR0|Q5JDR0_THEKO 227 ILK 229
                             776 PP

>> tr|Q5JG68|Q5JG68_THEKO  SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   4.8e-06   0.00074      75     129 ..      55     107 ..      46     146 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 4.8e-06
                             HH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE-- CS
                 UPF0020  75 aelklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnp 129
                             ++++ly++D  +++++ a++ a++ g++  ++f++a+a +L+ +++ +d++v+  
  tr|Q5JG68|Q5JG68_THEKO  55 QDVELYAIDGSEKMLEMAKKRAKELGMD--VKFKVAEAESLPFPDDFFDTVVSSF 107
                             56679******************98887..56666667777777778*****965 PP

>> tr|Q5JJ78|Q5JJ78_THEKO  Probable tRNA/rRNA methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.34        52      64      91 ..      74     104 ..      52     127 .. 0.80
   2 !   12.4   0.0   7.8e-05     0.012      43     130 ..     232     298 ..     213     306 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.34
                             S...HHHHHHHHHHHH--EEEEES-HHHHHH CS
                 UPF0020  64 e...lkaeaeeearaelklygsDldrrvvqg 91 
                             +    +++++++++++ ++ g D+  r+v g
  tr|Q5JJ78|Q5JJ78_THEKO  74 NkelFRERIRKANEYRKNVLGYDKAYRMVYG 104
                             145567888888999999********99975 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 7.8e-05
                             HHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--....STTS---EE CS
                 UPF0020  43 lIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNaekagvgdliefsqadaakLr....lkegevdvi 125
                             +I aa+ ga+                          ++++D+ + +++  +eNa+  gv+d++++ +  a  +     ++ +++d++
  tr|Q5JJ78|Q5JJ78_THEKO 232 AIHAAVAGADE-------------------------VVAVDKSPWAINMVKENAKLNGVEDKMKYIVGSAFPVMeemiKRGEKFDIV 293
                             55555444444.........................58******************************999887777555669**** PP

                             EE--- CS
                 UPF0020 126 vtnpP 130
                             + +pP
  tr|Q5JJ78|Q5JJ78_THEKO 294 ILDPP 298
                             ****9 PP

>> tr|Q5JHF7|Q5JHF7_THEKO  23S rRNA (Uracil-5-)-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   3.5e-05    0.0054      77     130 ..     300     350 ..     265     353 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 3.5e-05
                             --EEEEES-HHHHHHHHHHHHHTT-GGGEEE.EE--GGG--STTS---EEEE--- CS
                 UPF0020  77 lklygsDldrrvvqgareNaekagvgdlief.sqadaakLrlkegevdvivtnpP 130
                              k+ g+++++ +v+ a++Na+  gv+ +  + +++d+ +L     e+d++v +pP
  tr|Q5JHF7|Q5JHF7_THEKO 300 FKVEGIEINPFAVEMAKKNAQINGVDAEFRVgEDKDVNSLS----EYDTVVVDPP 350
                             56889********************9877662345555555....8********9 PP

>> tr|Q5JJF0|Q5JJF0_THEKO  Ribosomal RNA small subunit methyltransferase C OS=Thermococcus kodakarensis (strain ATCC BAA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0   2.8e-05    0.0043      79     130 ..      81     130 ..      70     189 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 2.8e-05
                             EEEEES-HHHHHHHHHHHHHTT-GGG.EEEEE--GGG--STTS---EEEE--- CS
                 UPF0020  79 lygsDldrrvvqgareNaekagvgdl.iefsqadaakLrlkegevdvivtnpP 130
                             ++  D +rr+v  a++N++  gv +  + + +     +   e ++d+i+tnpP
  tr|Q5JJF0|Q5JJF0_THEKO  81 VVMTDVNRRAVSIAKKNLKINGVRNAeVRWGS-LYEPVA-GE-KFDSIITNPP 130
                             55689*****************9875155555.677777.55.8********* PP

>> tr|Q5JIX8|Q5JIX8_THEKO  N5-glutamine methyltransferase, HemK family OS=Thermococcus kodakarensis (strain ATCC BAA-918
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   0.0   3.3e-05    0.0051      78     132 ..      57     109 ..      44     115 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.3e-05
                             -.EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----- CS
                 UPF0020  78 k.lygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYG 132
                             + + g+D+++ +v+ areNa+  g+ + +ef+  d   +++ +ge+dvi  n PY 
  tr|Q5JIX8|Q5JIX8_THEKO  57 RwVLGVDINPLAVELARENARINGIIN-VEFRLSD--LFENVSGEFDVITFNAPYL 109
                             3489***************98766654.3333333..33456699**********5 PP

>> tr|Q5JH73|Q5JH73_THEKO  Uncharacterized protein OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.0   8.1e-05     0.012      78     113 ..     107     141 ..      73     158 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 8.1e-05
                             -EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GG CS
                 UPF0020  78 klygsDldrrvvqgareNaekagvgdliefsqadaa 113
                             + yg+D+d+  ++ ar+Naek+gv+++ ef +ad  
  tr|Q5JH73|Q5JH73_THEKO 107 RAYGIDIDPLKIEFARRNAEKYGVSNI-EFINADSL 141
                             389*********************975.45444544 PP

>> tr|Q5JHQ2|Q5JHQ2_THEKO  SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0    0.0003     0.046      78     125 ..      62     107 ..      55     109 .. 0.90
   2 ?   -3.7   0.0       6.7     1e+03     149     173 ..     125     149 ..     120     157 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.0003
                             -EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EE CS
                 UPF0020  78 klygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvi 125
                             +++g+D+ r ++++are a++   + ++ef + da++L+ +++++d +
  tr|Q5JHQ2|Q5JHQ2_THEKO  62 EVVGLDNSRFMLEKAREFAKE--KESRVEFIEGDARELPFENDSFDYV 107
                             589**************9996..6789************999999987 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 6.7
                             HHHHHHH-TT..-EEEEEESSHHHH CS
                 UPF0020 149 lrelkrvlrgggrlvlltsenkale 173
                              +e +rvl+ gg+ +l +++ +al 
  tr|Q5JHQ2|Q5JHQ2_THEKO 125 FKETARVLKPGGKFILQFTDLRALL 149
                             4666788888888888888777765 PP

>> tr|Q5JEE1|Q5JEE1_THEKO  Protein-L-isoaspartate O-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       2.7   4.1e+02      18      34 ..      67      83 ..      62      90 .. 0.74
   2 ?   10.0   0.0   0.00042     0.064      75     126 ..      99     149 ..      89     152 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 2.7
                            HHHHHHTT--TTS-EEE CS
                 UPF0020 18 aalvrlagwkpgepllD 34
                            a +++la++kpg   l+
  tr|Q5JEE1|Q5JEE1_THEKO 67 AIMLELADLKPGMNVLE 83
                            67999999999988776 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00042
                             HH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEE CS
                 UPF0020  75 aelklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdviv 126
                             ++  +y ++ ++++v+ ar+N+e+agv++   +     + ++ +++ +d i+
  tr|Q5JEE1|Q5JEE1_THEKO  99 VKTDVYTIERIPELVEFARRNLERAGVKNVHVILGDGTKGFP-PKAPYDRII 149
                             4556999********************988777766777788.777888776 PP

>> tr|Q5JE68|Q5JE68_THEKO  23S rRNA (Uracil-5-)-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   0.00033     0.051      74     130 ..     301     353 ..     279     366 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00033
                             HHH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE--- CS
                 UPF0020  74 raelklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpP 130
                             +++ ++ g++l++ +v+ a++Nae  +v+ + ++  a+ + +     ++d++v +pP
  tr|Q5JE68|Q5JE68_THEKO 301 KRRFQVEGIELNPFAVEIANKNAEINNVDATFKVGRAEETPIG----KYDTVVVDPP 353
                             5678899****************************99999776....89*******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (197 nodes)
Target sequences:                         2301  (637680 residues searched)
Passed MSV filter:                        93  (0.0404172); expected 46.0 (0.02)
Passed bias filter:                       86  (0.0373751); expected 46.0 (0.02)
Passed Vit filter:                        23  (0.00999565); expected 2.3 (0.001)
Passed Fwd filter:                        15  (0.0065189); expected 0.0 (1e-05)
Initial search space (Z):               2301  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.02
# Mc/sec: 6281.15
//
[ok]