# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/UPF0020.hmm.txt # target sequence database: proteomes/Thermococcus_kodakarensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: UPF0020 [M=197] Accession: PF01170.17 Description: Putative RNA methylase family UPF0020 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-40 136.2 0.0 1e-39 133.4 0.0 2.0 1 tr|Q5JEM0|Q5JEM0_THEKO Predicted N6-adenine-specific DNA met 2e-27 93.3 0.0 1.6e-26 90.3 0.0 2.0 1 tr|Q5JID5|Q5JID5_THEKO N2, N2-dimethylguanosine tRNA methylt 1.7e-14 51.1 0.0 7.6e-12 42.4 0.0 3.5 2 tr|Q5JEC3|Q5JEC3_THEKO Predicted DNA methylase OS=Thermococc 1.4e-11 41.6 0.1 2.2e-11 40.9 0.1 1.4 1 tr|Q5JDP7|Q5JDP7_THEKO Predicted DNA methylase OS=Thermococc 2.5e-05 21.2 0.0 0.00036 17.4 0.0 2.5 2 tr|Q5JE97|Q5JE97_THEKO Predicted endonuclease-methyltransfer 9.1e-05 19.3 0.0 0.00014 18.7 0.0 1.3 1 tr|Q5JDR0|Q5JDR0_THEKO SAM-dependent methyltransferase, UPF0 0.0003 17.6 0.0 0.00074 16.3 0.0 1.6 1 tr|Q5JG68|Q5JG68_THEKO SAM-dependent methyltransferase, UbiE 0.0004 17.2 0.1 0.012 12.4 0.0 2.7 2 tr|Q5JJ78|Q5JJ78_THEKO Probable tRNA/rRNA methyltransferase 0.0022 14.8 0.0 0.0054 13.5 0.0 1.6 1 tr|Q5JHF7|Q5JHF7_THEKO 23S rRNA (Uracil-5-)-methyltransferas 0.003 14.3 0.0 0.0043 13.9 0.0 1.4 1 tr|Q5JJF0|Q5JJF0_THEKO Ribosomal RNA small subunit methyltra 0.0031 14.3 0.0 0.0051 13.6 0.0 1.3 1 tr|Q5JIX8|Q5JIX8_THEKO N5-glutamine methyltransferase, HemK 0.0071 13.1 0.0 0.012 12.3 0.0 1.4 1 tr|Q5JH73|Q5JH73_THEKO Uncharacterized protein OS=Thermococc ------ inclusion threshold ------ 0.02 11.7 0.0 0.046 10.5 0.0 1.5 2 tr|Q5JHQ2|Q5JHQ2_THEKO SAM-dependent methyltransferase, UbiE 0.027 11.3 0.0 0.064 10.0 0.0 1.5 2 tr|Q5JEE1|Q5JEE1_THEKO Protein-L-isoaspartate O-methyltransf 0.03 11.1 0.0 0.051 10.3 0.0 1.4 1 tr|Q5JE68|Q5JE68_THEKO 23S rRNA (Uracil-5-)-methyltransferas Domain annotation for each sequence (and alignments): >> tr|Q5JEM0|Q5JEM0_THEKO Predicted N6-adenine-specific DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 133.4 0.0 6.6e-42 1e-39 1 195 [. 191 358 .. 191 360 .. 0.96 Alignments for each domain: == domain 1 score: 133.4 bits; conditional E-value: 6.6e-42 -SSS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HH CS UPF0020 1 RgyRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrr 87 R +R++++pa+Lk+++A al++la+ + g +++DP+CGsGtilIE al g + ++g+++ r+ tr|Q5JEM0|Q5JEM0_THEKO 191 RPWRVYDHPAHLKASIANALIELAEPN-GGSFIDPFCGSGTILIELALRGYKGR------------------------IIGLEKYRK 252 78***********************97.56899*****************9999........................9******** PP HHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT..-EEEEEESSHHHHH CS UPF0020 88 vvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgggrlvlltsenkalek 174 +++ga+ Na +agv d+ief q da+kL + ++vd v+n+PYG ++g+k ++ +LY +f +el++vl++ r v++t+e+ka+e+ tr|Q5JEM0|Q5JEM0_THEKO 253 HIRGAEMNALSAGVLDKIEFIQGDATKLSQYVESVDFAVSNLPYGLKIGRKSMIPRLYMAFFSELSKVLEK--RGVFITTEKKAIER 337 *****************************8889**************************************..************** PP CC---ESEEEEEEETTEEEEE CS UPF0020 175 aleeralrkvkeknvklglll 195 a+ ++ ++ ++ + + +g+l+ tr|Q5JEM0|Q5JEM0_THEKO 338 AILDNGFKIKHHRLIGHGGLM 358 *******99999988888876 PP >> tr|Q5JID5|Q5JID5_THEKO N2, N2-dimethylguanosine tRNA methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 90.3 0.0 1.1e-28 1.6e-26 3 171 .. 156 298 .. 154 324 .. 0.91 Alignments for each domain: == domain 1 score: 90.3 bits; conditional E-value: 1.1e-28 SS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHH CS UPF0020 3 yRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvv 89 R+f+ p +L +++++alv+l+++ ++ +lDP+ G G+ilIEa+llg +++ g+D+ +++v tr|Q5JID5|Q5JID5_THEKO 156 HRPFFRPISLHPRVSRALVNLTKA--TREILDPFMGAGGILIEAGLLGLRVY--------------------------GVDIRPEMV 214 79*******************965..678*********************99..........................********* PP HHHHHHHHHTT-GGGEEEEE--GGG--..STTS---EEEE----------HHHH.HHHHHHHHHHHHHH-TT..-EEEEEESSHH CS UPF0020 90 qgareNaekagvgdliefsqadaakLr..lkegevdvivtnpPYGerlgskkal.ekLYseflrelkrvlrgggrlvlltsenka 171 +ga++N++++gv d +++ da+ L+ +++++++++t+pPYG + + ++++ ++LY++ lr++ +vl+ ggrl+++++++ + tr|Q5JID5|Q5JID5_THEKO 215 EGAETNLKHYGVRDY-TLKLGDATRLEdlFPDKKFEAVATDPPYGTAATLAGRKrDELYRKALRSIYNVLEDGGRLAIAFPTDFN 298 ************996.688899****9987888**************999988879************************98755 PP >> tr|Q5JEC3|Q5JEC3_THEKO Predicted DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.0 0.29 44 140 163 .. 87 110 .. 84 121 .. 0.84 2 ! 42.4 0.0 5e-14 7.6e-12 12 170 .. 175 321 .. 166 324 .. 0.84 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.29 HHHHHHHHHHHHHHHH-TT..-EE CS UPF0020 140 alekLYseflrelkrvlrgggrlv 163 + +kL++++++e+k++++++g + tr|Q5JEC3|Q5JEC3_THEKO 87 SDWKLWRKLGSEIKKRFKEEGSAK 110 5699***************98765 PP == domain 2 score: 42.4 bits; conditional E-value: 5e-14 S-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHH.. CS UPF0020 12 LketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNa.. 96 + ++LA+ +v+l+++++g ++lDP+CG Gt+ E l+g +++ gsD d+ ++ a++N+ tr|Q5JEC3|Q5JEC3_THEKO 175 IPPRLARIMVNLTEVRKG-SFLDPFCGIGTVVQEFVLQGLTAY--------------------------GSDRDEGQIRDAKKNLtw 234 6789***********998.699******************999..........................***************944 PP ..HHTT-GGGEEEEE--GGG--.STTS---EEEE----..........------HHHHHHHHHHHHHHHHHH-TT..-EEEEEESSH CS UPF0020 97 ..ekagvgdliefsqadaakLr.lkegevdvivtnpPY..........GerlgskkalekLYseflrelkrvlrgggrlvlltsenk 170 ++ +++++ ++++ da+kL+ ++ +d+ivt+p Ge+++ +++l+++Y ++ ++++ vl+++g+ v++++++k tr|Q5JEC3|Q5JEC3_THEKO 235 lrKEFRLKNSAHLEVCDARKLKkCFRQRFDAIVTEPYLgkplkrhpsrGEAIKLANELDRFYYSVFESFADVLKRNGKVVFVFPAYK 321 4457889999************755669******975522223333335566666788999*********************99876 PP >> tr|Q5JDP7|Q5JDP7_THEKO Predicted DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.9 0.1 1.5e-13 2.2e-11 78 138 .. 72 129 .. 43 133 .. 0.92 Alignments for each domain: == domain 1 score: 40.9 bits; conditional E-value: 1.5e-13 -EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------H CS UPF0020 78 klygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgsk 138 ++y+++ d+++++ areNa++ gv+d+ief++ad+ ++ +vd+++ npP+G ++++ tr|Q5JDP7|Q5JDP7_THEKO 72 NVYAVERDKEALEIARENARSLGVEDKIEFVNADVSEFS-V--NVDTVIMNPPFGSQVKHA 129 489*********************************999.4..5***********998765 PP >> tr|Q5JE97|Q5JE97_THEKO Predicted endonuclease-methyltransferase fusion protein OS=Thermococcus kodakarensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 2.4e-06 0.00036 27 96 .. 385 451 .. 371 472 .. 0.72 2 ? 0.3 0.0 0.39 59 115 131 .. 582 596 .. 561 613 .. 0.76 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 2.4e-06 -TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SS.HHHHHHHHHHHH--EEEEES-HHHHHHHHHHH CS UPF0020 27 kpgepllDPmCGsGtilIEaallganiapgllrefvle.lkaeaeeearaelklygsDldrrvvqgareNa 96 +p+++ lDP CGsGt+l+ a ++a ++++ + a+++ + + +++g+Dl++ +v +ar N tr|Q5JE97|Q5JE97_THEKO 385 NPEKRVLDPACGSGTFLVLAI----KRAKEWGLRHWGTsADAQLRLLESITSNIVGIDLNPLAVLAARGNY 451 5899*************8554....4443333445554255555566667777***********9999985 PP == domain 2 score: 0.3 bits; conditional E-value: 0.39 --STTS---EEEE---- CS UPF0020 115 LrlkegevdvivtnpPY 131 L + g++d +++npP+ tr|Q5JE97|Q5JE97_THEKO 582 L--TIGNFDFVIGNPPW 596 3..45689********9 PP >> tr|Q5JDR0|Q5JDR0_THEKO SAM-dependent methyltransferase, UPF0020 family OS=Thermococcus kodakarensis (strain ATCC BAA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 9.4e-07 0.00014 68 153 .. 141 229 .. 103 238 .. 0.79 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 9.4e-07 HHHHHHHHH--EEEEES-HHHHHHHHHH..HHHTT-GGGEEEEE--GGG--..STTS---EEEE----------HHHHHHHHHHHHH CS UPF0020 68 eaeeearaelklygsDldrrvvqgareN..aekagvgdliefsqadaakLr..lkegevdvivtnpPYGerlgskkalekLYseflr 150 +a e+ ++ + ++ +++d++v++ ar N ++ g++i++ q da ++ k++++dvi+ +pP +l + e++Y+e+ r tr|Q5JDR0|Q5JDR0_THEKO 141 TAIEASKRGAYVITIEKDPNVIEIARINpwSRELFTGGKIQVIQGDAFEVVkkFKQASFDVIIHDPPR-FSLAGHLYSEEFYRELFR 226 55566666777999**************55577889***********9998666677**********3.344445555888888877 PP HHH CS UPF0020 151 elk 153 lk tr|Q5JDR0|Q5JDR0_THEKO 227 ILK 229 776 PP >> tr|Q5JG68|Q5JG68_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 4.8e-06 0.00074 75 129 .. 55 107 .. 46 146 .. 0.81 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 4.8e-06 HH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE-- CS UPF0020 75 aelklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnp 129 ++++ly++D +++++ a++ a++ g++ ++f++a+a +L+ +++ +d++v+ tr|Q5JG68|Q5JG68_THEKO 55 QDVELYAIDGSEKMLEMAKKRAKELGMD--VKFKVAEAESLPFPDDFFDTVVSSF 107 56679******************98887..56666667777777778*****965 PP >> tr|Q5JJ78|Q5JJ78_THEKO Probable tRNA/rRNA methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 0.34 52 64 91 .. 74 104 .. 52 127 .. 0.80 2 ! 12.4 0.0 7.8e-05 0.012 43 130 .. 232 298 .. 213 306 .. 0.79 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.34 S...HHHHHHHHHHHH--EEEEES-HHHHHH CS UPF0020 64 e...lkaeaeeearaelklygsDldrrvvqg 91 + +++++++++++ ++ g D+ r+v g tr|Q5JJ78|Q5JJ78_THEKO 74 NkelFRERIRKANEYRKNVLGYDKAYRMVYG 104 145567888888999999********99975 PP == domain 2 score: 12.4 bits; conditional E-value: 7.8e-05 HHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--....STTS---EE CS UPF0020 43 lIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNaekagvgdliefsqadaakLr....lkegevdvi 125 +I aa+ ga+ ++++D+ + +++ +eNa+ gv+d++++ + a + ++ +++d++ tr|Q5JJ78|Q5JJ78_THEKO 232 AIHAAVAGADE-------------------------VVAVDKSPWAINMVKENAKLNGVEDKMKYIVGSAFPVMeemiKRGEKFDIV 293 55555444444.........................58******************************999887777555669**** PP EE--- CS UPF0020 126 vtnpP 130 + +pP tr|Q5JJ78|Q5JJ78_THEKO 294 ILDPP 298 ****9 PP >> tr|Q5JHF7|Q5JHF7_THEKO 23S rRNA (Uracil-5-)-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.0 3.5e-05 0.0054 77 130 .. 300 350 .. 265 353 .. 0.86 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 3.5e-05 --EEEEES-HHHHHHHHHHHHHTT-GGGEEE.EE--GGG--STTS---EEEE--- CS UPF0020 77 lklygsDldrrvvqgareNaekagvgdlief.sqadaakLrlkegevdvivtnpP 130 k+ g+++++ +v+ a++Na+ gv+ + + +++d+ +L e+d++v +pP tr|Q5JHF7|Q5JHF7_THEKO 300 FKVEGIEINPFAVEMAKKNAQINGVDAEFRVgEDKDVNSLS----EYDTVVVDPP 350 56889********************9877662345555555....8********9 PP >> tr|Q5JJF0|Q5JJF0_THEKO Ribosomal RNA small subunit methyltransferase C OS=Thermococcus kodakarensis (strain ATCC BAA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 2.8e-05 0.0043 79 130 .. 81 130 .. 70 189 .. 0.80 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 2.8e-05 EEEEES-HHHHHHHHHHHHHTT-GGG.EEEEE--GGG--STTS---EEEE--- CS UPF0020 79 lygsDldrrvvqgareNaekagvgdl.iefsqadaakLrlkegevdvivtnpP 130 ++ D +rr+v a++N++ gv + + + + + e ++d+i+tnpP tr|Q5JJF0|Q5JJF0_THEKO 81 VVMTDVNRRAVSIAKKNLKINGVRNAeVRWGS-LYEPVA-GE-KFDSIITNPP 130 55689*****************9875155555.677777.55.8********* PP >> tr|Q5JIX8|Q5JIX8_THEKO N5-glutamine methyltransferase, HemK family OS=Thermococcus kodakarensis (strain ATCC BAA-918 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 0.0 3.3e-05 0.0051 78 132 .. 57 109 .. 44 115 .. 0.76 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 3.3e-05 -.EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----- CS UPF0020 78 k.lygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYG 132 + + g+D+++ +v+ areNa+ g+ + +ef+ d +++ +ge+dvi n PY tr|Q5JIX8|Q5JIX8_THEKO 57 RwVLGVDINPLAVELARENARINGIIN-VEFRLSD--LFENVSGEFDVITFNAPYL 109 3489***************98766654.3333333..33456699**********5 PP >> tr|Q5JH73|Q5JH73_THEKO Uncharacterized protein OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 0.0 8.1e-05 0.012 78 113 .. 107 141 .. 73 158 .. 0.77 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 8.1e-05 -EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GG CS UPF0020 78 klygsDldrrvvqgareNaekagvgdliefsqadaa 113 + yg+D+d+ ++ ar+Naek+gv+++ ef +ad tr|Q5JH73|Q5JH73_THEKO 107 RAYGIDIDPLKIEFARRNAEKYGVSNI-EFINADSL 141 389*********************975.45444544 PP >> tr|Q5JHQ2|Q5JHQ2_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.0003 0.046 78 125 .. 62 107 .. 55 109 .. 0.90 2 ? -3.7 0.0 6.7 1e+03 149 173 .. 125 149 .. 120 157 .. 0.71 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.0003 -EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EE CS UPF0020 78 klygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvi 125 +++g+D+ r ++++are a++ + ++ef + da++L+ +++++d + tr|Q5JHQ2|Q5JHQ2_THEKO 62 EVVGLDNSRFMLEKAREFAKE--KESRVEFIEGDARELPFENDSFDYV 107 589**************9996..6789************999999987 PP == domain 2 score: -3.7 bits; conditional E-value: 6.7 HHHHHHH-TT..-EEEEEESSHHHH CS UPF0020 149 lrelkrvlrgggrlvlltsenkale 173 +e +rvl+ gg+ +l +++ +al tr|Q5JHQ2|Q5JHQ2_THEKO 125 FKETARVLKPGGKFILQFTDLRALL 149 4666788888888888888777765 PP >> tr|Q5JEE1|Q5JEE1_THEKO Protein-L-isoaspartate O-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 2.7 4.1e+02 18 34 .. 67 83 .. 62 90 .. 0.74 2 ? 10.0 0.0 0.00042 0.064 75 126 .. 99 149 .. 89 152 .. 0.81 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2.7 HHHHHHTT--TTS-EEE CS UPF0020 18 aalvrlagwkpgepllD 34 a +++la++kpg l+ tr|Q5JEE1|Q5JEE1_THEKO 67 AIMLELADLKPGMNVLE 83 67999999999988776 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00042 HH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEE CS UPF0020 75 aelklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdviv 126 ++ +y ++ ++++v+ ar+N+e+agv++ + + ++ +++ +d i+ tr|Q5JEE1|Q5JEE1_THEKO 99 VKTDVYTIERIPELVEFARRNLERAGVKNVHVILGDGTKGFP-PKAPYDRII 149 4556999********************988777766777788.777888776 PP >> tr|Q5JE68|Q5JE68_THEKO 23S rRNA (Uracil-5-)-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.00033 0.051 74 130 .. 301 353 .. 279 366 .. 0.93 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00033 HHH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE--- CS UPF0020 74 raelklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpP 130 +++ ++ g++l++ +v+ a++Nae +v+ + ++ a+ + + ++d++v +pP tr|Q5JE68|Q5JE68_THEKO 301 KRRFQVEGIELNPFAVEIANKNAEINNVDATFKVGRAEETPIG----KYDTVVVDPP 353 5678899****************************99999776....89*******9 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (197 nodes) Target sequences: 2301 (637680 residues searched) Passed MSV filter: 93 (0.0404172); expected 46.0 (0.02) Passed bias filter: 86 (0.0373751); expected 46.0 (0.02) Passed Vit filter: 23 (0.00999565); expected 2.3 (0.001) Passed Fwd filter: 15 (0.0065189); expected 0.0 (1e-05) Initial search space (Z): 2301 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.02 # Mc/sec: 6281.15 // [ok]