# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/UPF0020.hmm.txt # target sequence database: proteomes/Xenopus_tropicalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: UPF0020 [M=197] Accession: PF01170.17 Description: Putative RNA methylase family UPF0020 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-43 148.4 0.0 4.8e-43 147.6 0.0 1.4 1 tr|F7C781|F7C781_XENTR THUMP domain-containing 3 OS=Xen 3.1e-25 89.4 0.0 5.4e-24 85.4 0.0 2.2 1 tr|F6R2E5|F6R2E5_XENTR THUMP domain-containing 2 OS=Xen 8.2e-12 45.6 0.0 2.5e-11 44.1 0.0 1.7 1 tr|F7DXV8|F7DXV8_XENTR tRNA methyltransferase 11 homolo 3.6e-08 33.8 0.2 4e-07 30.3 0.2 2.1 1 tr|F7AIW5|F7AIW5_XENTR Methyltransferase-like 5 OS=Xeno 1.5e-05 25.2 0.0 3.4e-05 24.0 0.0 1.6 1 tr|F6YTE0|F6YTE0_XENTR Trimethylguanosine synthase 1 OS 0.00067 19.8 0.0 0.0012 19.0 0.0 1.3 1 tr|F7C1D7|F7C1D7_XENTR HemK methyltransferase family me 0.0052 16.9 0.0 0.15 12.1 0.0 2.3 2 tr|F7DZT0|F7DZT0_XENTR Uncharacterized protein OS=Xenop ------ inclusion threshold ------ 0.015 15.4 0.3 0.053 13.6 0.3 1.8 1 tr|B1H336|B1H336_XENTR LOC100145545 protein OS=Xenopus 0.17 12.0 0.0 0.28 11.3 0.0 1.4 1 tr|A0A1B8Y2Q5|A0A1B8Y2Q5_XENTR Uncharacterized protein (Fragmen Domain annotation for each sequence (and alignments): >> tr|F7C781|F7C781_XENTR THUMP domain-containing 3 OS=Xenopus tropicalis OX=8364 GN=thumpd3 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 147.6 0.0 1.8e-46 4.8e-43 2 195 .. 294 475 .. 292 477 .. 0.91 Alignments for each domain: == domain 1 score: 147.6 bits; conditional E-value: 1.8e-46 SSS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHH CS UPF0020 2 gyRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrv 88 ++++f gp++L++tLA++++rl++++p ++++DPmCG+G+i+IE+ + + ++++++ ++ +++++ tr|F7C781|F7C781_XENTR 294 NITHF-GPTTLRSTLAYGMLRLCDLQPSDVIIDPMCGTGAIPIEGVSEWPGSFF-------------LAGDNNKQAVNRTGSNIQSL 366 55555.5****************************************9999992.............34466777778888888999 PP HHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT...-EEEEEESSHHHHH CS UPF0020 89 vqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgg.grlvlltsenkalek 174 +++ ++ e+a + +i+++ +d+ +L+l++g+vdvivt++P+G+r+gskk++++LY+++lre++rv+r g gr+vllt+++k++ k tr|F7C781|F7C781_XENTR 367 LRKHQS-PESAPSNLRIDAVHWDISSLPLRDGSVDVIVTDMPFGKRMGSKKKNWDLYPACLREMSRVCRAGtGRAVLLTHDRKCFIK 452 999776.688999********************************************************999*************** PP CC---..ESEEEEEEETTEEEEE CS UPF0020 175 aleer..alrkvkeknvklglll 195 al+++ +rkv+ ++v++g+l+ tr|F7C781|F7C781_XENTR 453 ALAKAghLWRKVHTVWVNIGGLH 475 ****9989************998 PP >> tr|F6R2E5|F6R2E5_XENTR THUMP domain-containing 2 OS=Xenopus tropicalis OX=8364 GN=thumpd2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.4 0.0 2e-27 5.4e-24 3 168 .. 256 397 .. 255 421 .. 0.95 Alignments for each domain: == domain 1 score: 85.4 bits; conditional E-value: 2e-27 SS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHH CS UPF0020 3 yRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvv 89 +R++ ++ L++t A a+ +la+++ g lDPmCG Gtil+Eaa + + g+D++ + tr|F6R2E5|F6R2E5_XENTR 256 KRDYIRNTGLRSTTAWAMGTLAELHVGALVLDPMCGVGTILLEAAKEWPFGH------------------------FLGVDNNDLQL 318 689999****************************************999888........................89********* PP HHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----------HHHHHHHHHHHHHHHHHH-TT..-EEEEEES CS UPF0020 90 qgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYGerlgskkalekLYseflrelkrvlrgggrlvlltse 168 + a +N + ag+++ ie+ + + +L+ ++++d+++++ P+G++ +s k++++L + + re++rv+r gg +vll+s+ tr|F6R2E5|F6R2E5_XENTR 319 ESAVSNVKGAGLDGAIELLKGSVLDLPFVSESMDAVICDIPFGRKFTSSKNMKDLLPDIIREMQRVVRVGGAIVLLLSQ 397 ***************************8888**************************************9999998865 PP >> tr|F7DXV8|F7DXV8_XENTR tRNA methyltransferase 11 homolog OS=Xenopus tropicalis OX=8364 GN=trmt11 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.1 0.0 9.3e-15 2.5e-11 3 140 .. 194 324 .. 193 330 .. 0.82 Alignments for each domain: == domain 1 score: 44.1 bits; conditional E-value: 9.3e-15 SS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHH CS UPF0020 3 yRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvv 89 +R+f g++++ + L+ + + a++kp+++ +DP+ G+G++l+ a ga++ e ++ + + +++r ++k +g D + tr|F7DXV8|F7DXV8_XENTR 194 KRHFIGNTSMDAGLSFIMANHARVKPNDMVFDPFVGTGGLLVSSAHFGAYVC---GTEIDYNTVHGLGKATRMNQKWRGPDENI--- 274 79**************************************************...44566777788888888999999999875... PP HHHHHHHHHTT-GGGE.EEEE--GGG--.STTS---EEEE----------HHH CS UPF0020 90 qgareNaekagvgdli.efsqadaakLr.lkegevdvivtnpPYGerlgskka 140 r N++++g+++ ++ da k +k +d+i+t+pPYG+r ++ k+ tr|F7DXV8|F7DXV8_XENTR 275 ---RANLRQYGLEKYYlDVLLSDASKPVwRKAPLFDAIITDPPYGIRESTRKT 324 ...5799999999864134344444333356668*************888775 PP >> tr|F7AIW5|F7AIW5_XENTR Methyltransferase-like 5 OS=Xenopus tropicalis OX=8364 GN=mettl5 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 0.2 1.5e-10 4e-07 13 142 .. 32 141 .. 25 187 .. 0.76 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 1.5e-10 -HHHHHHHHHHTT--....TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHH CS UPF0020 13 ketLAaalvrlagwk....pgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareN 95 ++ +Aa++++ + ++++ +D CG G + I aa+lga g+D d+ +++ ++N tr|F7AIW5|F7AIW5_XENTR 32 RPHIAACMLYTIHNTfndiEDKVVADLGCGCGVLSIGAAMLGAGLC-------------------------LGLDVDEDALDIFKTN 93 6677777765544332222778888888999999999999999988.........................7*************** PP HHHTT-GGGEEEEE--GGG--..STTS---EEEE----------HHHHH CS UPF0020 96 aekagvgdliefsqadaakLr..lkegevdvivtnpPYGerlgskkale 142 e+ ++++ i++ q d+++L+ +++vd+++ npP+G + ++ ++ tr|F7AIW5|F7AIW5_XENTR 94 TEEFELTN-IDMIQFDICSLPpdCLSKSVDTVIMNPPFGTKHNKGMDMT 141 *****975.899999******997777************8765544433 PP >> tr|F6YTE0|F6YTE0_XENTR Trimethylguanosine synthase 1 OS=Xenopus tropicalis OX=8364 GN=tgs1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 0.0 1.3e-08 3.4e-05 71 132 .. 704 764 .. 672 818 .. 0.85 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 1.3e-08 HHHHHH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE----- CS UPF0020 71 eearaelklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtnpPYG 132 + a+a +++++D+d+ ++ ar+Nae +gv+d+ief d+ L ++ + d++ pP+G tr|F6YTE0|F6YTE0_XENTR 704 QFAKAGNRVIAVDIDPVKLDFARNNAEVYGVTDRIEFIRGDFMLLA-QDLKADAVFLSPPWG 764 4444555689*********************************999.8889**********9 PP >> tr|F7C1D7|F7C1D7_XENTR HemK methyltransferase family member 1 OS=Xenopus tropicalis OX=8364 GN=hemk1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.0 4.3e-07 0.0012 75 131 .. 142 202 .. 128 211 .. 0.89 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 4.3e-07 HH--EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--....STTS---EEEE---- CS UPF0020 75 aelklygsDldrrvvqgareNaekagvgdliefsqadaakLr....lkegevdvivtnpPY 131 +++++ ++D+ +++v+ +++Na + g++++i++ +d+ + + l+ g vdv+v+npPY tr|F7C1D7|F7C1D7_XENTR 142 PQARITAIDKTKAAVKLTEDNAVSLGLQNQIQVLLLDILADPpdplLMWGPVDVLVSNPPY 202 56779********************************9876678888999*********** PP >> tr|F7DZT0|F7DZT0_XENTR Uncharacterized protein OS=Xenopus tropicalis OX=8364 GN=loc100124841 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.1 0.0 5.7e-05 0.15 79 128 .. 75 121 .. 64 145 .. 0.84 2 ? 2.2 0.0 0.061 1.6e+02 77 126 .. 303 351 .. 295 375 .. 0.81 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 5.7e-05 EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE- CS UPF0020 79 lygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtn 128 + ++D+ ++ ++ +N + g + i+f qad+++L l+++++d i +n tr|F7DZT0|F7DZT0_XENTR 75 VTAVDFMQNFIE---KNQKDNGFRGNITFLQADVTNLDLPNESFDFIFSN 121 566666666665...688999***************************99 PP == domain 2 score: 2.2 bits; conditional E-value: 0.061 --EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEE CS UPF0020 77 lklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdviv 126 +++ g+Dl +++v+ a e a ++ l++f+ da+k +e+++dv+ tr|F7DZT0|F7DZT0_XENTR 303 VEVLGMDLSSNMVEIAMERAIIEKIP-LVQFEIGDATKRSFSEASFDVVY 351 5689************9998766554.68888888888777788888875 PP >> tr|B1H336|B1H336_XENTR LOC100145545 protein OS=Xenopus tropicalis OX=8364 GN=trmt2a PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.3 2e-05 0.053 7 83 .. 416 485 .. 413 501 .. 0.74 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2e-05 S---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEE CS UPF0020 7 ngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallganiapgllrefvlelkaeaeeearaelklygsD 83 + ++p e L +a+ a+++++++ lD CG+Gti I a +++++ + el +ea ++a+a+++l +D tr|B1H336|B1H336_XENTR 416 QVNTPAAEVLYSAIADWAQLDQNTTVLDVCCGTGTIGISLAKKVKKVVGI-------ELCQEAIADAKANAQLNNLD 485 5667777889999**************************99999999943.......34444444444444443333 PP >> tr|A0A1B8Y2Q5|A0A1B8Y2Q5_XENTR Uncharacterized protein (Fragment) OS=Xenopus tropicalis OX=8364 GN=XENTR_v90027386mg # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.00011 0.28 47 104 .. 98 155 .. 96 180 .. 0.88 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00011 HHHHTT--TTTT----SSHHHHHHHHHHHH--EEEEES-HHHHHHHHHHHHHTT-GGG CS UPF0020 47 allganiapgllrefvlelkaeaeeearaelklygsDldrrvvqgareNaekagvgdl 104 + ++++i p ++ ++++++ a e +++++ g+Dl ++++ + Nae+ + ++ tr|A0A1B8Y2Q5|A0A1B8Y2Q5_XENTR 98 CAMKESIRPSNMDRNKVNVNWPADEVVETQAPCKGLDLSHKMISPSPLNAENGQKQQP 155 789999******99999999999999999999*******************9887765 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (197 nodes) Target sequences: 24182 (11782085 residues searched) Passed MSV filter: 662 (0.0273757); expected 483.6 (0.02) Passed bias filter: 528 (0.0218344); expected 483.6 (0.02) Passed Vit filter: 59 (0.00243983); expected 24.2 (0.001) Passed Fwd filter: 9 (0.000372178); expected 0.2 (1e-05) Initial search space (Z): 24182 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.22u 0.01s 00:00:00.23 Elapsed: 00:00:00.11 # Mc/sec: 21100.64 // [ok]