# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/WBS_methylT.hmm.txt
# target sequence database: proteomes/Amphimedon_queenslandica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: WBS_methylT [M=82]
Accession: PF12589.7
Description: Methyltransferase involved in Williams-Beuren syndrome
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.5e-22 81.4 4.0 2.4e-22 80.7 4.0 1.3 1 tr|A0A1X7VIY9|A0A1X7VIY9_AMPQE Uncharacterized protein OS=Amphi
------ inclusion threshold ------
0.039 15.9 3.0 0.039 15.9 3.0 5.6 7 tr|A0A1X7V6P6|A0A1X7V6P6_AMPQE Uncharacterized protein OS=Amphi
Domain annotation for each sequence (and alignments):
>> tr|A0A1X7VIY9|A0A1X7VIY9_AMPQE Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 80.7 4.0 1.1e-26 2.4e-22 1 82 [] 200 277 .. 200 277 .. 0.91
Alignments for each domain:
== domain 1 score: 80.7 bits; conditional E-value: 1.1e-26
WBS_methylT 1 LfaGkseqqqlpkglgedgeeeseeaeqvkyekrrrkrkkrkkkkkkavksreWilkKKerrrkkGkeVkrdSKYTGRk 79
Lf+G +++ +lpk+lg+++ ++ e++q+++ ++r+k k r++k+k +vksr+Wi++KKer++++GkeV++dSKYTGRk
tr|A0A1X7VIY9|A0A1X7VIY9_AMPQE 200 LFTG-GAPVALPKALGTEDLKS--EQNQISFVEARKKLK-RRGKDKVPVKSRDWIIAKKERKQRQGKEVRPDSKYTGRK 274
7999.89************765..46*******999988.577777799****************************** PP
WBS_methylT 80 Rka 82
Rk+
tr|A0A1X7VIY9|A0A1X7VIY9_AMPQE 275 RKP 277
*95 PP
>> tr|A0A1X7V6P6|A0A1X7V6P6_AMPQE Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 15.9 3.0 1.8e-06 0.039 19 81 .. 181 248 .. 164 249 .. 0.75
2 ? -0.4 0.2 0.22 4.8e+03 24 45 .. 282 311 .. 265 328 .. 0.54
3 ? 0.7 6.3 0.1 2.2e+03 8 59 .. 414 466 .. 408 472 .. 0.76
4 ? -4.0 0.2 2 4.3e+04 29 40 .. 539 550 .. 527 573 .. 0.57
5 ? -2.8 0.7 1.3 2.8e+04 7 20 .. 787 800 .. 775 824 .. 0.53
6 ? -2.0 0.4 0.71 1.5e+04 10 44 .. 904 938 .. 898 968 .. 0.70
7 ? -1.8 0.4 0.59 1.3e+04 24 41 .. 1013 1030 .. 995 1054 .. 0.52
Alignments for each domain:
== domain 1 score: 15.9 bits; conditional E-value: 1.8e-06
WBS_methylT 19 geeeseeaeqvkyekrrrkrkkr.....kkkkkkavksreWilkKKerrrkkGkeVkrdSKYTGRkRk 81
+++++ee+e+v++++++r ++ +++++++++ ++++ +K + +++k keVk +S + GRkR+
tr|A0A1X7V6P6|A0A1X7V6P6_AMPQE 181 ESDKEEEEEKVQIKEQERVIETIiidddNDDDDDDEEVKDYLKQKDDFEQRKMKEVKYTSPFRGRKRP 248
23344478999999999966665554334444455559*****************************7 PP
== domain 2 score: -0.4 bits; conditional E-value: 0.22
WBS_methylT 24 e......eaeqvkyekrrr..krkkrkkkk 45
+ +a+qv++ +++ kkrk +
tr|A0A1X7V6P6|A0A1X7V6P6_AMPQE 282 KettlkpSAKQVHVHVQENkeGTKKRKTVR 311
333444544455444444400344333333 PP
== domain 3 score: 0.7 bits; conditional E-value: 0.1
WBS_methylT 8 qqqlpkglgedgeeese.eaeqvkyekrrrkrkkrkkkkkkavksreWilkKK 59
+++ ++++ ++ +e++ +e+v++++r+++++k+ k +++ k+re + +K
tr|A0A1X7V6P6|A0A1X7V6P6_AMPQE 414 REEIEEAKEIKELSERQkVKERVDIKRREEMKQKEDMKLREEIKRREEVNEKE 466
4566666666655544447899********99999999999999999887775 PP
== domain 4 score: -4.0 bits; conditional E-value: 2
WBS_methylT 29 vkyekrrrkrkk 40
++ kr+++rk+
tr|A0A1X7V6P6|A0A1X7V6P6_AMPQE 539 IDEGKRTKRRKS 550
333333333332 PP
== domain 5 score: -2.8 bits; conditional E-value: 1.3
WBS_methylT 7 eqqqlpkglgedge 20
++++ g+g +g+
tr|A0A1X7V6P6|A0A1X7V6P6_AMPQE 787 KKKSSESGKGSSGT 800
23333344444443 PP
== domain 6 score: -2.0 bits; conditional E-value: 0.71
WBS_methylT 10 qlpkglgedgeeeseeaeqvkyekrrrkrkkrkkk 44
+l g+++++++++ +++ +++kr+ + +++kk+
tr|A0A1X7V6P6|A0A1X7V6P6_AMPQE 904 KLATGRKKQASATEPKKKLLDISKRKPPTSTEKKQ 938
55666666665555577888888888877776655 PP
== domain 7 score: -1.8 bits; conditional E-value: 0.59
WBS_methylT 24 eeaeqvkyekrrrkrkkr 41
++++ v + +++++++++
tr|A0A1X7V6P6|A0A1X7V6P6_AMPQE 1013 NNNSIVGIITKKEENDAK 1030
234444444444443333 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (82 nodes)
Target sequences: 43435 (14716620 residues searched)
Passed MSV filter: 3362 (0.077403); expected 868.7 (0.02)
Passed bias filter: 1125 (0.0259008); expected 868.7 (0.02)
Passed Vit filter: 102 (0.00234834); expected 43.4 (0.001)
Passed Fwd filter: 5 (0.000115115); expected 0.4 (1e-05)
Initial search space (Z): 43435 [actual number of targets]
Domain search space (domZ): 2 [number of targets reported over threshold]
# CPU time: 0.24u 0.01s 00:00:00.25 Elapsed: 00:00:00.12
# Mc/sec: 10056.36
//
[ok]