# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/WBS_methylT.hmm.txt
# target sequence database:        proteomes/Strongylocentrotus_purpuratus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       WBS_methylT  [M=82]
Accession:   PF12589.7
Description: Methyltransferase involved in Williams-Beuren syndrome
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    4.4e-18   66.5   6.9    7.1e-18   65.8   6.9    1.3  1  tr|W4Z511|W4Z511_STRPU  Uncharacterized protein OS=Strongyloc
  ------ inclusion threshold ------
        1.6   10.2   3.8       0.75   11.2   0.2    2.3  2  tr|W4XD29|W4XD29_STRPU  Uncharacterized protein OS=Strongyloc


Domain annotation for each sequence (and alignments):
>> tr|W4Z511|W4Z511_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.8   6.9     5e-22   7.1e-18       1      81 [.     203     279 ..     203     280 .. 0.86

  Alignments for each domain:
  == domain 1  score: 65.8 bits;  conditional E-value: 5e-22
             WBS_methylT   1 LfaGkseqqqlpkglgedgeeeseeaeqvkyekrrrkrkkrkkkkkkavksreWilkKKerrrkkGk.eVkrdSKYTGRkRk 81 
                             LfaG  ++ +lpk+lg+ ++      +q ++++ r + ++ k+k  + +ksreWi +KKerrr++Gk eV++dSKYTGRkR 
  tr|W4Z511|W4Z511_STRPU 203 LFAG-VSNPTLPKALGTGNQRGVA--TQASFTDSRMRYRNMKGK--SVKKSREWIKEKKERRRRQGKgEVRPDSKYTGRKRS 279
                             8999.89999*******9976655..888888888877755555..4568*******************************6 PP

>> tr|W4XD29|W4XD29_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.2   5.2e-05      0.75      37      71 ..     303     337 ..     275     339 .. 0.62
   2 ?   -2.4   0.3      0.92   1.3e+04      18      41 ..     353     378 ..     345     384 .. 0.56

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 5.2e-05
             WBS_methylT  37 krkkrkkkkkkavk.....sreWilkKKerrrkkGkeVkr 71 
                             + +   ++     +     sr+W +++Ke+ +++G ++k+
  tr|W4XD29|W4XD29_STRPU 303 RGQGDGGD-----TegkpdSRDWSFAQKELLKHQGIDIKE 337
                             22222222.....123356****************99986 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.92
             WBS_methylT  18 dgeeese..eaeqvkyekrrrkrkkr 41 
                             ++ee ++  e+++ +ye++ +  +k+
  tr|W4XD29|W4XD29_STRPU 353 EKEEVDQllEQQRLDYESKLQALQKQ 378
                             22233335677777777776655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (82 nodes)
Target sequences:                        28594  (14266044 residues searched)
Passed MSV filter:                      3043  (0.106421); expected 571.9 (0.02)
Passed bias filter:                      836  (0.0292369); expected 571.9 (0.02)
Passed Vit filter:                       131  (0.00458138); expected 28.6 (0.001)
Passed Fwd filter:                        11  (0.000384696); expected 0.3 (1e-05)
Initial search space (Z):              28594  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.28u 0.01s 00:00:00.29 Elapsed: 00:00:00.10
# Mc/sec: 11698.16
//
[ok]