# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/WD40.hmm.txt # target sequence database: proteomes/Homo_sapiens.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: WD40 [M=38] Accession: PF00400.32 Description: WD domain, G-beta repeat Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-69 230.8 18.3 5.7e-09 38.7 0.1 8.1 8 tr|G5EA46|G5EA46_HUMAN Dynein assembly factor with WDR rep 1.6e-69 230.3 18.3 6e-09 38.6 0.1 8.1 8 sp|Q8N136|DAW1_HUMAN Dynein assembly factor with WDR rep 3.2e-67 223.0 25.2 1.1e-08 37.7 0.1 9.0 8 sp|Q9NVX2|NLE1_HUMAN Notchless protein homolog 1 OS=Homo 2e-65 217.4 91.4 6.4e-05 25.8 0.2 27.4 18 tr|J3KNC1|J3KNC1_HUMAN Echinoderm microtubule-associated p 4.7e-65 216.2 91.4 6.6e-05 25.8 0.2 27.5 18 sp|Q05BV3|EMAL5_HUMAN Echinoderm microtubule-associated p 5.3e-65 216.0 91.4 6.6e-05 25.8 0.2 27.5 18 sp|Q05BV3-5|EMAL5_HUMAN Isoform 5 of Echinoderm microtubule 1.9e-64 214.2 86.3 0.00023 24.1 0.0 28.0 20 sp|Q6ZMW3|EMAL6_HUMAN Echinoderm microtubule-associated p 1.2e-63 211.7 22.6 2.2e-10 43.2 0.1 7.2 7 sp|Q8NBT0-2|POC1A_HUMAN Isoform 2 of POC1 centriolar protei 3.8e-63 210.1 22.6 2.6e-10 42.9 0.1 7.3 7 sp|Q8NBT0|POC1A_HUMAN POC1 centriolar protein homolog A O 6.4e-63 209.4 13.1 3.2e-08 36.3 0.2 7.3 7 sp|Q8TC44|POC1B_HUMAN POC1 centriolar protein homolog B O 1.8e-62 208.0 17.8 5.4e-08 35.6 0.3 7.7 7 sp|P43034|LIS1_HUMAN Platelet-activating factor acetylhy 4.1e-62 206.9 43.1 5.4e-08 35.6 0.2 13.5 11 sp|O14727-2|APAF_HUMAN Isoform 2 of Apoptotic protease-act 4.5e-62 206.7 43.1 5.5e-08 35.6 0.2 13.5 11 sp|O14727|APAF_HUMAN Apoptotic protease-activating facto 5.7e-62 206.4 19.9 2.5e-09 39.8 0.2 7.2 7 sp|P61964|WDR5_HUMAN WD repeat-containing protein 5 OS=H 1e-61 205.6 40.7 5.2e-08 35.6 0.2 12.5 11 sp|O14727-3|APAF_HUMAN Isoform 3 of Apoptotic protease-act 1.1e-61 205.5 40.7 5.3e-08 35.6 0.2 12.5 11 sp|O14727-4|APAF_HUMAN Isoform 4 of Apoptotic protease-act 7.6e-60 199.7 78.1 0.00021 24.2 0.0 26.4 19 sp|Q6ZMW3-2|EMAL6_HUMAN Isoform 2 of Echinoderm microtubule 7.4e-59 196.5 17.7 2.3e-08 36.7 0.1 7.3 7 sp|Q86VZ2|WDR5B_HUMAN WD repeat-containing protein 5B OS= 1.2e-56 189.5 11.3 6.3e-10 41.7 0.1 6.7 6 sp|Q15542|TAF5_HUMAN Transcription initiation factor TFI 2.8e-56 188.4 20.4 2.6e-08 36.6 0.2 11.1 10 sp|Q9UNX4|WDR3_HUMAN WD repeat-containing protein 3 OS=H 6.5e-55 184.1 18.0 2.2e-10 43.1 0.1 6.5 6 sp|Q8NBT0-3|POC1A_HUMAN Isoform 3 of POC1 centriolar protei 4.7e-54 181.3 13.1 2.9e-08 36.4 0.2 6.3 6 sp|Q8TC44-2|POC1B_HUMAN Isoform 2 of POC1 centriolar protei 8.1e-54 180.6 32.9 1.2e-06 31.3 0.2 11.9 11 sp|Q12788|TBL3_HUMAN Transducin beta-like protein 3 OS=H 1.5e-53 179.7 24.9 2.7e-09 39.7 0.0 7.1 7 sp|Q5JTN6|WDR38_HUMAN WD repeat-containing protein 38 OS= 4.1e-53 178.4 36.8 5e-08 35.7 0.2 11.6 10 tr|C9JLV4|C9JLV4_HUMAN Apoptotic protease-activating facto 4.4e-53 178.3 36.8 5.1e-08 35.7 0.2 11.6 10 sp|O14727-5|APAF_HUMAN Isoform 5 of Apoptotic protease-act 6.5e-53 177.7 6.2 2.7e-09 39.7 0.0 7.3 6 sp|O75529|TAF5L_HUMAN TAF5-like RNA polymerase II p300/CB 8.6e-53 177.3 25.9 1.3e-09 40.6 0.2 8.5 8 sp|O60907-2|TBL1X_HUMAN Isoform 2 of F-box-like/WD repeat-c 1.9e-52 176.3 25.3 1.7e-09 40.3 0.2 8.5 8 sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD repeat-containing pro 2.1e-52 176.1 25.9 1.5e-09 40.5 0.2 8.5 8 sp|O60907|TBL1X_HUMAN F-box-like/WD repeat-containing pro 2.3e-52 176.0 29.5 1e-06 31.6 0.2 10.9 10 tr|J3KNP2|J3KNP2_HUMAN Transducin beta-like protein 3 (Fra 1.4e-50 170.4 6.7 4.6e-06 29.5 0.0 7.1 7 sp|Q96DI7|SNR40_HUMAN U5 small nuclear ribonucleoprotein 8e-50 167.9 55.9 8.6e-05 25.4 0.0 17.9 13 sp|Q05BV3-2|EMAL5_HUMAN Isoform 2 of Echinoderm microtubule 2.3e-49 166.5 32.4 9.1e-07 31.7 0.1 7.7 7 tr|B7Z2C8|B7Z2C8_HUMAN F-box/WD repeat-containing protein 3.5e-49 165.9 25.4 1.6e-08 37.2 0.1 8.4 7 sp|Q9BQ87|TBL1Y_HUMAN F-box-like/WD repeat-containing pro 3.5e-49 165.9 25.3 3.6e-08 36.1 0.2 7.1 7 sp|P63244|GBLP_HUMAN Guanine nucleotide-binding protein 5.4e-49 165.3 32.4 1e-06 31.5 0.1 7.7 7 sp|Q969H0-4|FBXW7_HUMAN Isoform 4 of F-box/WD repeat-contai 5.5e-49 165.3 6.5 3.1e-11 45.8 0.2 6.6 6 sp|Q9BVA0|KTNB1_HUMAN Katanin p80 WD40 repeat-containing 8e-49 164.8 32.4 1.1e-06 31.4 0.1 7.8 7 sp|Q969H0-3|FBXW7_HUMAN Isoform 3 of F-box/WD repeat-contai 8.6e-49 164.7 32.4 1.1e-06 31.4 0.1 7.8 7 sp|Q969H0-2|FBXW7_HUMAN Isoform 2 of F-box/WD repeat-contai 2.3e-48 163.3 32.4 1.3e-06 31.2 0.1 7.8 7 sp|Q969H0|FBXW7_HUMAN F-box/WD repeat-containing protein 9.5e-47 158.2 31.7 3.6e-10 42.5 0.6 7.4 7 sp|O76071|CIAO1_HUMAN Probable cytosolic iron-sulfur prot 4.4e-46 156.1 10.4 5.6e-06 29.2 0.0 7.4 7 tr|B4DQJ1|B4DQJ1_HUMAN U5 small nuclear ribonucleoprotein 4.4e-46 156.1 14.3 5.1e-09 38.8 0.1 6.3 6 tr|C9JBF9|C9JBF9_HUMAN Dynein assembly factor with WDR rep 4.5e-46 156.1 14.3 5.1e-09 38.8 0.1 6.2 6 sp|Q8N136-2|DAW1_HUMAN Isoform 2 of Dynein assembly factor 2e-45 154.1 34.1 6.9e-06 28.9 0.2 15.1 13 tr|B4E0B6|B4E0B6_HUMAN Phosphatidylinositol 3,4,5-trisphos 3.9e-44 150.0 21.4 7.6e-08 35.1 0.0 7.1 7 sp|P62873|GBB1_HUMAN Guanine nucleotide-binding protein 5.8e-44 149.4 19.1 3.2e-06 30.0 0.0 7.4 7 tr|B8ZZF2|B8ZZF2_HUMAN WD repeat, SAM and U-box domain-con 7.7e-44 149.0 33.0 3.6e-05 26.6 0.1 10.8 10 sp|O75083|WDR1_HUMAN WD repeat-containing protein 1 OS=H 1.4e-43 148.1 19.1 3.7e-06 29.8 0.0 7.4 7 sp|Q8N9V3|WSDU1_HUMAN WD repeat, SAM and U-box domain-con 2.3e-43 147.5 4.3 6.4e-12 48.0 0.2 5.1 5 tr|H3BPK1|H3BPK1_HUMAN Katanin p80 WD40 repeat-containing 1.5e-42 144.9 20.8 6.6e-06 29.0 0.0 7.1 7 tr|E7EP32|E7EP32_HUMAN Guanine nucleotide-binding protein 2.6e-42 144.2 7.2 5.8e-10 41.8 0.1 5.7 5 sp|Q15542-2|TAF5_HUMAN Isoform Short of Transcription init 3.4e-42 143.8 21.1 1.4e-06 31.1 0.0 7.1 7 sp|Q9HAV0|GBB4_HUMAN Guanine nucleotide-binding protein 5e-42 143.3 20.8 8e-06 28.7 0.0 7.2 7 sp|P62879|GBB2_HUMAN Guanine nucleotide-binding protein 6.5e-42 142.9 7.0 1.2e-07 34.4 0.1 6.4 6 tr|B4E3L0|B4E3L0_HUMAN WD40 repeat-containing protein SMU1 1.6e-41 141.7 17.2 0.00011 25.1 0.1 8.4 8 sp|Q86TI4|WDR86_HUMAN WD repeat-containing protein 86 OS= 4e-41 140.4 17.8 7.9e-08 35.0 0.1 7.4 7 sp|O43172-2|PRP4_HUMAN Isoform 2 of U4/U6 small nuclear ri 4.1e-41 140.4 17.8 8e-08 35.0 0.1 7.4 7 sp|O43172|PRP4_HUMAN U4/U6 small nuclear ribonucleoprote 4.2e-41 140.4 21.1 9.4e-09 38.0 0.0 7.1 7 sp|Q9GZS3|WDR61_HUMAN WD repeat-containing protein 61 OS= 4.2e-41 140.3 22.0 1.2e-07 34.5 0.0 7.5 6 tr|K7EN33|K7EN33_HUMAN Notchless protein homolog 1 (Fragme 4.4e-41 140.3 34.7 2e-06 30.6 0.1 7.3 7 sp|Q6ZMY6-2|WDR88_HUMAN Isoform 2 of WD repeat-containing p 6.1e-41 139.8 22.6 3.2e-07 33.1 0.1 7.1 7 sp|P16520|GBB3_HUMAN Guanine nucleotide-binding protein 8e-41 139.5 21.0 2.9e-08 36.4 0.2 6.1 6 tr|J3KPE3|J3KPE3_HUMAN Guanine nucleotide-binding protein 1e-40 139.1 34.7 2.2e-06 30.5 0.1 7.3 7 sp|Q6ZMY6|WDR88_HUMAN WD repeat-containing protein 88 OS= 2e-40 138.2 2.9 6.3e-12 48.0 0.2 5.1 5 tr|H3BPD8|H3BPD8_HUMAN Katanin p80 WD40 repeat-containing 3.4e-40 137.5 8.9 2.1e-07 33.7 0.1 6.7 6 sp|Q2TAY7|SMU1_HUMAN WD40 repeat-containing protein SMU1 8.3e-40 136.2 21.3 9.7e-09 37.9 0.6 7.3 7 sp|O43660-2|PLRG1_HUMAN Isoform 2 of Pleiotropic regulator 8.4e-40 136.2 39.6 3.1e-05 26.8 0.2 18.6 14 tr|G3V5X7|G3V5X7_HUMAN Phosphatidylinositol 3,4,5-trisphos 9.8e-40 136.0 21.3 9.9e-09 37.9 0.6 7.3 7 tr|A8MW61|A8MW61_HUMAN Pleiotropic regulator 1 OS=Homo sap 9.8e-40 136.0 21.3 9.9e-09 37.9 0.6 7.3 7 sp|O43660|PLRG1_HUMAN Pleiotropic regulator 1 OS=Homo sap 9.8e-40 136.0 17.0 0.00015 24.6 0.1 8.7 8 sp|Q86TI4-1|WDR86_HUMAN Isoform 1 of WD repeat-containing p 1e-39 135.9 7.6 5.9e-08 35.4 0.1 8.1 6 sp|P35606|COPB2_HUMAN Coatomer subunit beta' OS=Homo sapi 1.5e-39 135.4 17.9 1.6e-06 31.0 0.2 7.8 6 sp|P53621|COPA_HUMAN Coatomer subunit alpha OS=Homo sapi 1.6e-39 135.3 17.9 1.6e-06 30.9 0.2 7.8 6 sp|P53621-2|COPA_HUMAN Isoform 2 of Coatomer subunit alpha 1.7e-39 135.3 38.2 3.2e-05 26.8 0.2 17.9 13 sp|Q99973-2|TEP1_HUMAN Isoform 2 of Telomerase protein com 1.8e-39 135.2 17.9 3e-06 30.1 0.2 7.6 7 sp|Q9UKB1-2|FBW1B_HUMAN Isoform A of F-box/WD repeat-contai 1.8e-39 135.2 36.3 2.3e-05 27.3 0.2 17.2 13 tr|G3V2A4|G3V2A4_HUMAN Phosphatidylinositol 3,4,5-trisphos 1.9e-39 135.1 17.9 3e-06 30.1 0.2 7.6 7 tr|B4DH70|B4DH70_HUMAN F-box/WD repeat-containing protein 1.9e-39 135.1 39.6 3.3e-05 26.8 0.2 18.5 13 sp|Q99973|TEP1_HUMAN Telomerase protein component 1 OS=H 2.4e-39 134.8 17.9 3.2e-06 30.0 0.2 7.8 7 sp|Q9UKB1|FBW1B_HUMAN F-box/WD repeat-containing protein 2.5e-39 134.7 17.9 3.1e-06 30.0 0.2 7.6 7 sp|Q9UKB1-3|FBW1B_HUMAN Isoform B of F-box/WD repeat-contai 2.5e-39 134.7 19.9 3.9e-08 36.0 0.6 6.1 6 tr|D6RAC2|D6RAC2_HUMAN Guanine nucleotide-binding protein 2.6e-39 134.7 17.0 7.8e-08 35.1 0.0 6.0 6 tr|I3L3N5|I3L3N5_HUMAN Platelet-activating factor acetylhy 3e-39 134.5 18.6 1e-05 28.3 0.2 7.6 7 tr|Q68DS0|Q68DS0_HUMAN F-box/WD repeat-containing protein 3.4e-39 134.3 18.6 1.1e-05 28.3 0.2 7.6 7 sp|Q9Y297-2|FBW1A_HUMAN Isoform 2 of F-box/WD repeat-contai 5.6e-39 133.6 18.6 1.1e-05 28.2 0.2 7.6 7 sp|Q9Y297|FBW1A_HUMAN F-box/WD repeat-containing protein 9.6e-39 132.9 21.5 3.2e-07 33.1 0.1 7.1 7 tr|E9PCP0|E9PCP0_HUMAN Guanine nucleotide-binding protein 1.3e-38 132.5 18.5 5.3e-07 32.4 0.1 7.7 7 sp|Q9NYS7|WSB2_HUMAN WD repeat and SOCS box-containing p 1.4e-38 132.4 19.4 8.9e-09 38.0 0.0 7.1 7 tr|H0YN81|H0YN81_HUMAN WD repeat-containing protein 61 (Fr 1.4e-38 132.4 18.5 5.3e-07 32.4 0.1 7.7 7 tr|F5H280|F5H280_HUMAN WD repeat and SOCS box-containing p 2.4e-38 131.6 18.8 5.5e-07 32.4 0.1 7.7 7 tr|B4DIE6|B4DIE6_HUMAN WD repeat and SOCS box-containing p 4.3e-38 130.8 25.4 0.03 17.4 0.0 12.6 11 sp|O60336-2|MABP1_HUMAN Isoform 2 of Mitogen-activated prot 5e-38 130.6 17.6 7.6e-08 35.1 0.0 5.8 5 tr|B4DF38|B4DF38_HUMAN Platelet-activating factor acetylhy 5.4e-38 130.5 29.0 2.6e-05 27.1 0.1 8.5 8 sp|O75083-3|WDR1_HUMAN Isoform 2 of WD repeat-containing p 2.1e-37 128.6 15.1 2.4e-09 39.9 0.4 7.1 6 tr|F5GYK2|F5GYK2_HUMAN Striatin-4 OS=Homo sapiens GN=STRN4 3.5e-37 128.0 24.7 0.038 17.1 0.0 12.7 11 sp|O60336|MABP1_HUMAN Mitogen-activated protein kinase-bi 4.2e-37 127.7 13.8 1.9e-05 27.5 0.0 7.5 7 tr|E5RIM3|E5RIM3_HUMAN Phospholipase A-2-activating protei 4.8e-37 127.5 25.2 0.038 17.1 0.0 12.7 11 sp|O60336-6|MABP1_HUMAN Isoform 6 of Mitogen-activated prot 5.9e-37 127.2 17.6 2.3e-08 36.7 0.2 5.3 5 tr|D6RHH4|D6RHH4_HUMAN Guanine nucleotide-binding protein 6e-37 127.2 21.3 4.9e-06 29.4 0.2 7.2 7 sp|O14775-2|GBB5_HUMAN Isoform 2 of Guanine nucleotide-bin 8.5e-37 126.7 15.1 2.9e-09 39.6 0.4 7.0 6 sp|Q9NRL3|STRN4_HUMAN Striatin-4 OS=Homo sapiens GN=STRN4 9.1e-37 126.6 15.1 2.9e-09 39.6 0.4 7.0 6 tr|F8VYA6|F8VYA6_HUMAN Striatin-4 OS=Homo sapiens GN=STRN4 1.3e-36 126.1 6.3 5.7e-08 35.5 0.1 7.7 5 tr|B4DZI8|B4DZI8_HUMAN Coatomer protein complex, subunit b 1.4e-36 126.0 4.1 2.8e-07 33.3 0.0 6.6 6 sp|O43815-2|STRN_HUMAN Isoform 2 of Striatin OS=Homo sapie 1.9e-36 125.7 21.6 5.7e-06 29.2 0.2 7.3 7 sp|O14775|GBB5_HUMAN Guanine nucleotide-binding protein 2.2e-36 125.4 4.1 3.1e-07 33.2 0.0 6.6 6 sp|O43815|STRN_HUMAN Striatin OS=Homo sapiens GN=STRN PE 2.9e-36 125.0 13.8 2.6e-05 27.1 0.0 7.8 7 sp|Q9Y263|PLAP_HUMAN Phospholipase A-2-activating protei 1e-35 123.3 39.0 0.00069 22.6 0.2 19.7 15 sp|Q96KV7|WDR90_HUMAN WD repeat-containing protein 90 OS= 1e-35 123.3 39.0 0.00069 22.6 0.2 19.7 15 tr|F8VUX9|F8VUX9_HUMAN WD repeat-containing protein 90 OS= 1.4e-35 122.9 16.1 4.8e-06 29.4 0.0 6.1 6 tr|B3KPU1|B3KPU1_HUMAN Guanine nucleotide-binding protein 1.4e-35 122.9 20.1 1.9e-05 27.5 0.4 8.7 7 sp|Q6RI45-5|BRWD3_HUMAN Isoform 5 of Bromodomain and WD rep 1.6e-35 122.7 18.8 3.6e-06 29.8 0.2 6.2 6 sp|O14775-3|GBB5_HUMAN Isoform 3 of Guanine nucleotide-bin 2.6e-35 122.0 21.4 3.4e-08 36.2 0.2 6.1 5 tr|D6R9L0|D6R9L0_HUMAN Guanine nucleotide-binding protein 3.2e-35 121.7 11.9 1.6e-05 27.8 0.0 7.4 7 sp|O60508|PRP17_HUMAN Pre-mRNA-processing factor 17 OS=Ho 3.9e-35 121.4 13.2 9.7e-05 25.3 0.5 8.8 8 sp|Q9NSI6-3|BRWD1_HUMAN Isoform C of Bromodomain and WD rep 4.1e-35 121.4 17.2 3.5e-07 33.0 0.1 7.3 6 sp|Q9Y6I7|WSB1_HUMAN WD repeat and SOCS box-containing p 4.4e-35 121.3 8.0 0.00031 23.7 0.0 8.1 8 sp|Q9BVC4-5|LST8_HUMAN Isoform 4 of Target of rapamycin co 5.1e-35 121.1 13.2 0.0001 25.2 0.5 8.8 8 sp|Q9NSI6-2|BRWD1_HUMAN Isoform B of Bromodomain and WD rep 6.2e-35 120.8 7.7 0.00031 23.7 0.0 8.1 8 sp|Q9BVC4|LST8_HUMAN Target of rapamycin complex subunit 6.4e-35 120.8 13.2 0.0001 25.2 0.5 8.8 8 sp|Q9NSI6|BRWD1_HUMAN Bromodomain and WD repeat-containin 7.6e-35 120.6 20.3 2.9e-05 26.9 0.4 8.8 7 sp|Q6RI45-2|BRWD3_HUMAN Isoform 2 of Bromodomain and WD rep 9.6e-35 120.2 9.2 5.4e-06 29.2 0.0 6.1 6 tr|H0YAU9|H0YAU9_HUMAN Phospholipase A-2-activating protei 1e-34 120.1 23.1 2.4e-08 36.7 0.2 5.8 5 tr|D6R9Z1|D6R9Z1_HUMAN Guanine nucleotide-binding protein 1.1e-34 120.1 11.6 2e-07 33.7 0.0 7.2 6 sp|Q9UMS4|PRP19_HUMAN Pre-mRNA-processing factor 19 OS=Ho 1.3e-34 119.9 20.1 2.5e-05 27.1 0.4 8.7 7 sp|Q6RI45|BRWD3_HUMAN Bromodomain and WD repeat-containin 1.3e-34 119.8 9.2 5.4e-09 38.7 0.0 5.1 5 tr|H0YL19|H0YL19_HUMAN WD repeat-containing protein 61 OS= 1.9e-34 119.3 13.1 1.5e-07 34.2 0.1 7.0 6 sp|Q13033-2|STRN3_HUMAN Isoform Alpha of Striatin-3 OS=Homo 2.8e-34 118.8 21.5 5e-08 35.7 0.6 6.3 6 tr|D6REE5|D6REE5_HUMAN Guanine nucleotide-binding protein 2.8e-34 118.7 9.6 1.9e-07 33.8 0.1 5.2 5 sp|Q9Y6I7-2|WSB1_HUMAN Isoform 2 of WD repeat and SOCS box 3.8e-34 118.3 0.2 3.2e-09 39.5 0.0 6.3 6 sp|Q9Y3F4|STRAP_HUMAN Serine-threonine kinase receptor-as 4e-34 118.3 12.6 3.6e-06 29.8 0.0 7.3 7 sp|Q676U5-5|A16L1_HUMAN Isoform 5 of Autophagy-related prot 4e-34 118.3 13.1 1.7e-07 34.0 0.1 7.1 6 sp|Q13033|STRN3_HUMAN Striatin-3 OS=Homo sapiens GN=STRN3 8e-34 117.3 9.0 1.1e-08 37.7 0.2 4.2 4 tr|B4DIH4|B4DIH4_HUMAN POC1 centriolar protein homolog B O 1.9e-33 116.1 3.5 2.5e-06 30.3 0.1 8.0 6 sp|P57737|CORO7_HUMAN Coronin-7 OS=Homo sapiens GN=CORO7 2.5e-33 115.7 24.1 2.9e-08 36.4 0.2 6.0 5 tr|H0Y8W2|H0Y8W2_HUMAN Guanine nucleotide-binding protein 3.8e-33 115.2 32.3 0.00014 24.7 0.5 7.3 7 sp|Q9GZL7|WDR12_HUMAN Ribosome biogenesis protein WDR12 O 4e-33 115.1 12.6 5.1e-06 29.3 0.0 7.4 7 sp|Q676U5-2|A16L1_HUMAN Isoform 2 of Autophagy-related prot 4.8e-33 114.9 29.9 5.7e-06 29.2 0.1 7.1 6 tr|B4DYB5|B4DYB5_HUMAN Sperm-associated antigen 16 protein 5.2e-33 114.7 12.6 5.3e-06 29.3 0.0 7.4 7 sp|Q676U5|A16L1_HUMAN Autophagy-related protein 16-1 OS=H 5.5e-33 114.7 3.5 2.9e-06 30.1 0.1 7.9 6 sp|P57737-3|CORO7_HUMAN Isoform 3 of Coronin-7 OS=Homo sapi 5.6e-33 114.6 11.3 2e-05 27.4 0.3 7.5 7 tr|H0YI78|H0YI78_HUMAN Kinesin-like protein KIF21A (Fragme 6.1e-33 114.5 12.6 5.5e-06 29.2 0.0 7.5 7 tr|E7EVC7|E7EVC7_HUMAN Autophagy-related protein 16-1 OS=H 7.1e-33 114.3 13.7 0.00016 24.6 0.1 8.6 7 sp|Q8WWQ0|PHIP_HUMAN PH-interacting protein OS=Homo sapi 7.1e-33 114.3 31.9 0.0003 23.7 1.8 12.2 10 sp|Q6IA86|ELP2_HUMAN Elongator complex protein 2 OS=Homo 8e-33 114.1 8.9 2.1e-08 36.9 0.2 4.3 4 tr|Q8IU52|Q8IU52_HUMAN POC1 centriolar protein homolog B O 9e-33 114.0 1.3 4.9e-08 35.7 0.2 4.1 4 sp|Q9NVX2-2|NLE1_HUMAN Isoform 2 of Notchless protein homo 9.8e-33 113.9 27.3 0.00027 23.9 1.8 11.8 9 sp|Q6IA86-2|ELP2_HUMAN Isoform 2 of Elongator complex prot 1.1e-32 113.8 17.3 1.7e-08 37.1 0.2 4.2 4 tr|D6RFX4|D6RFX4_HUMAN Guanine nucleotide-binding protein 1.3e-32 113.5 1.0 3.3e-09 39.4 0.0 6.4 6 tr|B4DNJ6|B4DNJ6_HUMAN Serine-threonine kinase receptor-as 1.4e-32 113.4 10.6 8.4e-05 25.5 0.1 7.1 7 sp|Q9BRX9|WDR83_HUMAN WD repeat domain-containing protein 1.8e-32 113.0 29.9 6.9e-06 28.9 0.1 7.0 6 sp|Q8N0X2|SPG16_HUMAN Sperm-associated antigen 16 protein 2.7e-32 112.5 11.5 0.038 17.1 0.0 11.1 8 sp|Q8N1V2-2|WDR16_HUMAN Isoform 2 of WD repeat-containing p 2.8e-32 112.4 23.1 0.024 17.7 0.0 12.7 11 sp|O43379|WDR62_HUMAN WD repeat-containing protein 62 OS= 2.9e-32 112.4 23.1 0.024 17.7 0.0 12.7 11 sp|O43379-4|WDR62_HUMAN Isoform 4 of WD repeat-containing p 3.2e-32 112.2 12.9 0.037 17.1 0.0 11.3 8 sp|Q8N1V2|WDR16_HUMAN WD repeat-containing protein 16 OS= 3.3e-32 112.2 2.1 1e-05 28.3 0.0 6.4 6 sp|Q05048|CSTF1_HUMAN Cleavage stimulation factor subunit 5.4e-32 111.5 29.2 0.00029 23.8 1.8 12.1 9 sp|Q6IA86-3|ELP2_HUMAN Isoform 3 of Elongator complex prot 5.9e-32 111.4 8.2 1.2e-09 40.8 0.2 7.4 6 tr|Q96Q25|Q96Q25_HUMAN KM-PA-2 protein OS=Homo sapiens GN= 7.5e-32 111.1 7.0 1.5e-09 40.5 0.2 7.5 6 sp|Q14137|BOP1_HUMAN Ribosome biogenesis protein BOP1 OS 1.1e-31 110.5 31.0 0.0003 23.7 1.8 11.9 9 sp|Q6IA86-5|ELP2_HUMAN Isoform 5 of Elongator complex prot 1.5e-31 110.1 11.3 3.2e-05 26.8 0.3 7.5 7 tr|H0YHT2|H0YHT2_HUMAN Kinesin-like protein KIF21A (Fragme 3e-31 109.2 24.6 7.5e-08 35.1 0.8 7.7 7 sp|Q6Q0C0-2|TRAF7_HUMAN Isoform 2 of E3 ubiquitin-protein l 3e-31 109.2 14.5 9.1e-06 28.5 0.0 7.4 6 sp|Q9C0J8|WDR33_HUMAN pre-mRNA 3' end processing protein 3.7e-31 108.9 30.1 4.2e-05 26.4 0.0 11.7 8 sp|Q05BV3-4|EMAL5_HUMAN Isoform 4 of Echinoderm microtubule 3.7e-31 108.9 8.0 4.2e-07 32.8 0.3 9.0 6 sp|A2RRH5|WDR27_HUMAN WD repeat-containing protein 27 OS= 4.4e-31 108.6 7.9 4.3e-07 32.7 0.3 8.9 6 tr|F2Z2U5|F2Z2U5_HUMAN WD repeat-containing protein 27 OS= 7e-31 108.0 33.0 0.00033 23.6 1.8 12.4 9 sp|Q6IA86-6|ELP2_HUMAN Isoform 6 of Elongator complex prot 7.9e-31 107.8 4.9 0.003 20.5 0.0 7.6 7 tr|H0YED0|H0YED0_HUMAN Kinesin-like protein KIF21B (Fragme 8e-31 107.8 39.4 2.8e-06 30.1 0.3 10.8 7 tr|E7ESC9|E7ESC9_HUMAN WD repeat-containing protein 17 OS= 8.1e-31 107.8 24.6 8.7e-08 34.9 0.8 7.8 7 sp|Q6Q0C0|TRAF7_HUMAN E3 ubiquitin-protein ligase TRAF7 O 1.1e-30 107.3 40.1 2.8e-06 30.2 0.3 10.9 7 sp|Q8IZU2-2|WDR17_HUMAN Isoform 2 of WD repeat-containing p 1.9e-30 106.6 15.5 0.034 17.2 0.0 10.8 9 sp|O60336-3|MABP1_HUMAN Isoform 3 of Mitogen-activated prot 2e-30 106.6 15.5 0.034 17.2 0.0 10.8 9 tr|C9JL14|C9JL14_HUMAN Mitogen-activated protein kinase-bi 4.7e-30 105.4 41.9 2.8e-06 30.1 0.3 10.9 7 tr|E7EP77|E7EP77_HUMAN Uncharacterized protein OS=Homo sap 5.3e-30 105.2 30.5 2e-07 33.8 0.1 12.1 7 sp|Q15269|PWP2_HUMAN Periodic tryptophan protein 2 homol 5.7e-30 105.1 41.9 2.9e-06 30.1 0.3 10.9 7 sp|Q8IZU2|WDR17_HUMAN WD repeat-containing protein 17 OS= 6.8e-30 104.9 11.3 5.8e-05 26.0 0.3 7.7 7 sp|Q7Z4S6-6|KI21A_HUMAN Isoform 6 of Kinesin-like protein K 7.1e-30 104.8 11.3 5.8e-05 26.0 0.3 7.7 7 sp|Q7Z4S6-3|KI21A_HUMAN Isoform 3 of Kinesin-like protein K 7.4e-30 104.8 11.3 5.9e-05 26.0 0.3 7.7 7 sp|Q7Z4S6-5|KI21A_HUMAN Isoform 5 of Kinesin-like protein K 8.3e-30 104.6 11.3 6e-05 25.9 0.3 7.7 7 sp|Q7Z4S6-2|KI21A_HUMAN Isoform 2 of Kinesin-like protein K 8.8e-30 104.5 11.3 6e-05 25.9 0.3 7.7 7 tr|F8WCP6|F8WCP6_HUMAN Kinesin-like protein KIF21A OS=Homo 8.8e-30 104.5 11.3 6e-05 25.9 0.3 7.7 7 sp|Q7Z4S6|KI21A_HUMAN Kinesin-like protein KIF21A OS=Homo 8.9e-30 104.5 11.3 6e-05 25.9 0.3 7.7 7 sp|Q7Z4S6-4|KI21A_HUMAN Isoform 4 of Kinesin-like protein K 2e-29 103.4 11.8 0.00044 23.2 0.1 8.0 7 tr|C9JG97|C9JG97_HUMAN Angio-associated migratory cell pro 2.5e-29 103.1 20.7 0.002 21.1 0.3 9.7 7 sp|Q9HC35-2|EMAL4_HUMAN Isoform 2 of Echinoderm microtubule 2.6e-29 103.0 11.8 0.00046 23.1 0.1 8.1 7 sp|Q13685|AAMP_HUMAN Angio-associated migratory cell pro 2.7e-29 103.0 11.8 0.00046 23.1 0.1 8.1 7 tr|C9JEH3|C9JEH3_HUMAN Angio-associated migratory cell pro 3.2e-29 102.7 11.2 0.0001 25.2 0.0 5.2 5 tr|C9JXA5|C9JXA5_HUMAN Guanine nucleotide-binding protein 4.4e-29 102.3 19.1 0.043 16.9 0.3 11.0 9 tr|F8WC21|F8WC21_HUMAN Mitogen-activated protein kinase-bi 4.8e-29 102.2 20.7 0.0021 21.0 0.3 9.6 7 sp|Q9HC35|EMAL4_HUMAN Echinoderm microtubule-associated p 5.3e-29 102.0 20.7 0.0021 21.0 0.3 9.6 7 tr|B5MBZ0|B5MBZ0_HUMAN Echinoderm microtubule-associated p 5.4e-29 102.0 30.3 1.3e-07 34.4 3.6 8.3 6 sp|P54198-2|HIRA_HUMAN Isoform Short of Protein HIRA OS=Ho 6.9e-29 101.7 16.3 2.5e-08 36.6 0.2 5.0 4 tr|H0YAM7|H0YAM7_HUMAN Guanine nucleotide-binding protein 9.2e-29 101.3 11.9 2.2e-07 33.6 0.1 5.2 5 tr|F5H0S8|F5H0S8_HUMAN Guanine nucleotide-binding protein 1.5e-28 100.7 28.7 0.00027 23.9 1.8 11.3 9 sp|Q6IA86-7|ELP2_HUMAN Isoform 7 of Elongator complex prot 1.7e-28 100.5 22.9 4.4e-06 29.5 0.1 5.6 5 sp|Q8N0X2-2|SPG16_HUMAN Isoform 2 of Sperm-associated antig 2.2e-28 100.1 8.4 0.00024 24.0 0.1 6.8 6 sp|Q8TAF3|WDR48_HUMAN WD repeat-containing protein 48 OS= 2.7e-28 99.8 15.8 0.00029 23.8 0.4 7.2 7 sp|O43818|U3IP2_HUMAN U3 small nucleolar RNA-interacting 2.8e-28 99.8 4.8 0.0073 19.3 0.0 7.8 7 sp|O75037-2|KI21B_HUMAN Isoform 2 of Kinesin-like protein K 2.9e-28 99.7 4.8 0.0073 19.3 0.0 7.8 7 sp|O75037|KI21B_HUMAN Kinesin-like protein KIF21B OS=Homo 7.5e-28 98.4 2.7 4.2e-06 29.6 0.1 6.4 5 tr|H0Y8P4|H0Y8P4_HUMAN U3 small nucleolar RNA-associated p 7.6e-28 98.4 2.9 3.9e-06 29.7 0.1 6.2 5 sp|Q8TED0|UTP15_HUMAN U3 small nucleolar RNA-associated p 8e-28 98.3 8.5 0.032 17.3 0.0 9.6 7 sp|Q8N1V2-3|WDR16_HUMAN Isoform 3 of WD repeat-containing p 8.4e-28 98.3 5.0 1.9e-05 27.5 0.0 6.3 6 sp|Q9UM11-3|FZR_HUMAN Isoform 3 of Fizzy-related protein 9.3e-28 98.1 2.0 0.00025 24.0 0.0 6.2 6 tr|H3BSZ4|H3BSZ4_HUMAN Target of rapamycin complex subunit 1.1e-27 97.9 9.4 4.6e-07 32.6 0.3 9.0 6 sp|A2RRH5-4|WDR27_HUMAN Isoform 4 of WD repeat-containing p 1.1e-27 97.8 2.8 3.7e-06 29.7 0.1 5.7 5 tr|B4DXK8|B4DXK8_HUMAN U3 small nucleolar RNA-associated p 1.2e-27 97.7 6.6 0.00023 24.1 0.0 6.1 6 sp|Q9BVC4-3|LST8_HUMAN Isoform 2 of Target of rapamycin co 1.4e-27 97.5 5.7 3.6e-07 33.0 0.3 7.7 5 sp|A2RRH5-2|WDR27_HUMAN Isoform 2 of WD repeat-containing p 1.5e-27 97.5 12.4 3.2e-05 26.8 0.0 7.3 7 tr|H0YG45|H0YG45_HUMAN Autophagy-related protein 16-2 (Fra 1.7e-27 97.3 1.5 1.4e-05 27.9 0.0 6.3 5 tr|Q5SRN1|Q5SRN1_HUMAN Pre-mRNA-processing factor 17 OS=Ho 2.9e-27 96.6 3.5 3.5e-09 39.3 0.0 3.9 3 tr|H3BQA8|H3BQA8_HUMAN WD repeat-containing protein 61 (Fr 2.9e-27 96.6 10.4 4.1e-05 26.5 0.0 6.2 5 sp|Q9H7D7-2|WDR26_HUMAN Isoform 2 of WD repeat-containing p 3.2e-27 96.4 15.3 1.8e-08 37.1 0.2 5.3 5 tr|H0YAF8|H0YAF8_HUMAN Guanine nucleotide-binding protein 3.3e-27 96.4 10.2 0.00015 24.7 0.1 6.5 5 tr|B4DJF1|B4DJF1_HUMAN WD repeat-containing protein 86 OS= 3.6e-27 96.3 10.5 4.2e-05 26.4 0.0 6.2 5 sp|Q9H7D7|WDR26_HUMAN WD repeat-containing protein 26 OS= 4.2e-27 96.0 12.4 3.8e-05 26.6 0.0 7.4 7 tr|H0YF72|H0YF72_HUMAN Autophagy-related protein 16-2 (Fra 4.4e-27 96.0 4.8 0.0072 19.3 0.0 7.8 7 sp|O75037-3|KI21B_HUMAN Isoform 3 of Kinesin-like protein K 4.7e-27 95.9 4.8 0.0073 19.3 0.0 7.8 7 sp|O75037-4|KI21B_HUMAN Isoform 4 of Kinesin-like protein K 7.2e-27 95.3 1.7 0.00025 24.0 0.0 8.0 6 sp|P57737-4|CORO7_HUMAN Isoform 4 of Coronin-7 OS=Homo sapi 7.7e-27 95.2 17.6 0.011 18.7 0.3 9.7 8 sp|Q6IA86-4|ELP2_HUMAN Isoform 4 of Elongator complex prot 9e-27 95.0 35.8 1.7e-07 34.0 3.6 8.8 6 sp|P54198|HIRA_HUMAN Protein HIRA OS=Homo sapiens GN=HIR 9.6e-27 94.9 6.6 2.4e-05 27.2 0.0 6.5 6 sp|Q9UM11-2|FZR_HUMAN Isoform 2 of Fizzy-related protein 1e-26 94.9 6.6 2.4e-05 27.2 0.0 6.5 6 sp|Q9UM11|FZR_HUMAN Fizzy-related protein homolog OS=Ho 1.4e-26 94.4 12.4 4.5e-05 26.3 0.0 7.4 7 sp|Q8NAA4-2|A16L2_HUMAN Isoform 2 of Autophagy-related prot 1.4e-26 94.4 5.1 1.1e-08 37.7 0.2 3.3 3 tr|E9PD14|E9PD14_HUMAN Guanine nucleotide-binding protein 1.5e-26 94.3 5.1 1.1e-08 37.8 0.2 3.1 3 tr|D6RAU2|D6RAU2_HUMAN Guanine nucleotide-binding protein 2e-26 93.9 0.0 2e-09 40.1 0.0 4.4 4 tr|B0AZV0|B0AZV0_HUMAN Serine-threonine kinase receptor-as 2.4e-26 93.6 6.6 8.9e-08 34.9 0.1 6.2 5 tr|E9PF19|E9PF19_HUMAN Transducin beta-like protein 2 OS=H 2.5e-26 93.6 14.1 1.5e-05 27.8 0.4 5.5 5 sp|Q8N9V3-2|WSDU1_HUMAN Isoform 2 of WD repeat, SAM and U-b 3e-26 93.3 11.3 1.7e-08 37.2 0.6 4.1 4 tr|D6RBD0|D6RBD0_HUMAN Guanine nucleotide-binding protein 3.2e-26 93.3 21.4 1.3e-05 28.0 0.4 7.2 6 sp|Q12834|CDC20_HUMAN Cell division cycle protein 20 homo 3.3e-26 93.2 14.7 1.4e-06 31.1 0.0 5.6 5 sp|Q09028-4|RBBP4_HUMAN Isoform 4 of Histone-binding protei 3.7e-26 93.1 14.5 0.00013 24.9 0.0 7.7 6 sp|O94967-2|WDR47_HUMAN Isoform 2 of WD repeat-containing p 4.1e-26 92.9 15.3 5.3e-05 26.1 0.0 6.4 6 sp|O00628|PEX7_HUMAN Peroxisomal targeting signal 2 rece 4.4e-26 92.8 6.5 1e-07 34.7 0.1 6.2 5 sp|Q9Y4P3|TBL2_HUMAN Transducin beta-like protein 2 OS=H 4.5e-26 92.8 14.7 1.5e-06 31.0 0.0 5.6 5 sp|Q09028-3|RBBP4_HUMAN Isoform 3 of Histone-binding protei 4.6e-26 92.7 24.7 2.6e-06 30.2 0.4 6.9 6 sp|Q9Y2I8|WDR37_HUMAN WD repeat-containing protein 37 OS= 4.7e-26 92.7 14.5 0.00014 24.8 0.0 7.7 6 sp|O94967|WDR47_HUMAN WD repeat-containing protein 47 OS= 4.8e-26 92.7 14.5 0.00014 24.8 0.0 7.7 6 sp|O94967-3|WDR47_HUMAN Isoform 3 of WD repeat-containing p 5.1e-26 92.6 14.5 0.00014 24.8 0.0 7.6 6 sp|O94967-4|WDR47_HUMAN Isoform 4 of WD repeat-containing p 5.2e-26 92.6 38.8 0.015 18.3 0.5 11.4 10 sp|O95834|EMAL2_HUMAN Echinoderm microtubule-associated p 5.4e-26 92.5 1.9 6.6e-08 35.3 0.1 3.1 3 tr|J3KTB3|J3KTB3_HUMAN WD repeat and SOCS box-containing p 5.6e-26 92.5 14.7 1.6e-06 30.9 0.0 5.6 5 sp|Q09028-2|RBBP4_HUMAN Isoform 2 of Histone-binding protei 5.7e-26 92.5 14.7 1.6e-06 30.9 0.0 5.6 5 sp|Q09028|RBBP4_HUMAN Histone-binding protein RBBP4 OS=Ho 6e-26 92.4 12.3 5.7e-05 26.0 0.0 7.4 7 sp|Q8NAA4|A16L2_HUMAN Autophagy-related protein 16-2 OS=H 1e-25 91.7 6.7 0.00024 24.0 0.1 6.8 6 sp|Q8TAF3-3|WDR48_HUMAN Isoform 3 of WD repeat-containing p 1.3e-25 91.3 14.9 8.4e-06 28.6 0.0 5.6 5 tr|E9PC52|E9PC52_HUMAN Histone-binding protein RBBP7 OS=Ho 1.5e-25 91.1 14.9 8.7e-06 28.6 0.0 5.6 5 sp|Q16576|RBBP7_HUMAN Histone-binding protein RBBP7 OS=Ho 2.3e-25 90.6 1.1 2.3e-05 27.3 1.6 6.2 4 sp|Q13347|EIF3I_HUMAN Eukaryotic translation initiation f 2.5e-25 90.5 13.6 0.00045 23.2 0.1 7.5 6 sp|Q5JSH3-3|WDR44_HUMAN Isoform 3 of WD repeat-containing p 3.4e-25 90.0 37.9 0.019 18.0 0.5 11.3 9 sp|O95834-2|EMAL2_HUMAN Isoform 2 of Echinoderm microtubule 4.9e-25 89.5 13.5 7.4e-05 25.6 0.3 7.0 5 sp|Q96J01|THOC3_HUMAN THO complex subunit 3 OS=Homo sapie 5.9e-25 89.3 26.5 1.3e-07 34.4 3.6 7.5 5 tr|L7N2F8|L7N2F8_HUMAN Protein HIRA OS=Homo sapiens GN=HIR 6e-25 89.2 16.7 9.9e-06 28.4 0.0 6.0 5 sp|Q16576-2|RBBP7_HUMAN Isoform 2 of Histone-binding protei 6.2e-25 89.2 37.6 0.021 17.9 0.5 11.3 8 sp|O95834-3|EMAL2_HUMAN Isoform 3 of Echinoderm microtubule 6.5e-25 89.1 5.6 1.4e-05 28.0 0.0 6.5 5 sp|Q8NA23-2|WDR31_HUMAN Isoform 2 of WD repeat-containing p 6.6e-25 89.1 5.6 1.4e-05 28.0 0.0 6.5 5 sp|Q8NA23|WDR31_HUMAN WD repeat-containing protein 31 OS= 7.5e-25 88.9 11.3 6.7e-05 25.8 0.3 6.2 5 tr|Q6NZ53|Q6NZ53_HUMAN THO complex subunit 3 OS=Homo sapie 9.4e-25 88.6 8.5 0.00098 22.1 0.1 7.5 5 tr|H7BY83|H7BY83_HUMAN WD repeat-containing protein 44 (Fr 1.5e-24 88.0 37.5 0.0004 23.3 0.2 10.2 7 tr|G3V195|G3V195_HUMAN Echinoderm microtubule associated p 1.8e-24 87.7 41.9 0.0021 21.1 0.6 11.0 8 tr|F8W717|F8W717_HUMAN Echinoderm microtubule-associated p 2e-24 87.6 1.7 7.4e-05 25.6 0.0 6.2 5 sp|Q6UXN9|WDR82_HUMAN WD repeat-containing protein 82 OS= 2.1e-24 87.5 41.9 0.0021 21.0 0.6 11.0 8 sp|O00423|EMAL1_HUMAN Echinoderm microtubule-associated p 2.2e-24 87.4 8.3 0.0011 21.9 0.1 7.4 5 sp|Q5JSH3|WDR44_HUMAN WD repeat-containing protein 44 OS= 2.7e-24 87.1 41.9 0.0022 21.0 0.6 11.0 8 sp|O00423-3|EMAL1_HUMAN Isoform 3 of Echinoderm microtubule 4.2e-24 86.5 14.2 7.1e-05 25.7 0.5 6.2 5 tr|F5GZ90|F5GZ90_HUMAN Denticleless protein homolog OS=Hom 5.9e-24 86.1 14.2 7.6e-05 25.6 0.5 6.2 5 sp|Q9NZJ0|DTL_HUMAN Denticleless protein homolog OS=Hom 7.8e-24 85.7 14.4 2.7e-05 27.0 0.1 7.0 6 sp|Q676U5-4|A16L1_HUMAN Isoform 4 of Autophagy-related prot 8.3e-24 85.6 10.0 8.8e-05 25.4 0.0 5.3 5 tr|C9JIS1|C9JIS1_HUMAN Guanine nucleotide-binding protein 1.6e-23 84.7 36.4 0.00056 22.9 0.2 10.1 7 sp|Q32P44|EMAL3_HUMAN Echinoderm microtubule-associated p 1.6e-23 84.7 36.4 0.00056 22.9 0.2 10.1 7 tr|B7WPE2|B7WPE2_HUMAN Echinoderm microtubule associated p 2.4e-23 84.1 4.5 0.00021 24.2 0.1 5.9 5 sp|Q8TAF3-4|WDR48_HUMAN Isoform 4 of WD repeat-containing p 2.7e-23 84.0 8.2 5.6e-07 32.3 0.0 4.2 4 tr|H0YF10|H0YF10_HUMAN Histone-binding protein RBBP4 (Frag 2.8e-23 83.9 11.7 1.4e-05 27.9 0.0 6.4 5 tr|H0Y9R3|H0Y9R3_HUMAN WD repeat-containing protein 26 (Fr 3.1e-23 83.8 30.8 1.6e-07 34.1 3.6 7.9 5 tr|F5H4M2|F5H4M2_HUMAN Protein HIRA OS=Homo sapiens GN=HIR 4.3e-23 83.4 10.9 8e-05 25.5 0.0 5.2 5 tr|F5H100|F5H100_HUMAN Guanine nucleotide-binding protein 4.4e-23 83.3 8.6 0.0014 21.6 0.0 8.6 7 sp|Q8IV35|WDR49_HUMAN WD repeat-containing protein 49 OS= 5.3e-23 83.1 3.8 7e-06 28.9 0.5 6.7 6 sp|Q5TAQ9|DCAF8_HUMAN DDB1- and CUL4-associated factor 8 7e-23 82.7 1.4 0.0002 24.3 0.1 5.1 5 tr|H3BN58|H3BN58_HUMAN Target of rapamycin complex subunit 1.4e-22 81.8 16.7 0.00019 24.3 0.5 7.3 7 sp|Q8TEB1-3|DCA11_HUMAN Isoform 3 of DDB1- and CUL4-associa 1.5e-22 81.7 13.4 1.8e-08 37.1 0.2 5.0 3 tr|D6RFZ9|D6RFZ9_HUMAN Guanine nucleotide-binding protein 1.5e-22 81.7 10.4 3.4e-05 26.7 0.0 6.4 6 tr|H0YG67|H0YG67_HUMAN Autophagy-related protein 16-2 (Fra 1.5e-22 81.6 12.5 5.8e-06 29.1 0.5 6.4 5 sp|Q13112|CAF1B_HUMAN Chromatin assembly factor 1 subunit 1.6e-22 81.6 4.9 0.13 15.4 0.0 7.1 6 sp|Q8NHY2-3|RFWD2_HUMAN Isoform 3 of E3 ubiquitin-protein l 2.2e-22 81.1 11.1 0.0017 21.3 0.0 6.5 5 sp|Q9NV06|DCA13_HUMAN DDB1- and CUL4-associated factor 13 2.6e-22 80.9 3.8 9.2e-06 28.5 0.5 6.7 6 tr|G3V3G9|G3V3G9_HUMAN DDB1- and CUL4-associated factor 8 3e-22 80.7 4.9 0.15 15.2 0.0 7.4 6 tr|H0Y339|H0Y339_HUMAN E3 ubiquitin-protein ligase RFWD2 ( 3.1e-22 80.6 8.2 9.5e-10 41.1 0.4 4.2 3 tr|M0QZM0|M0QZM0_HUMAN Striatin-4 (Fragment) OS=Homo sapie 3.2e-22 80.6 7.4 0.00023 24.1 0.0 6.2 6 tr|H0Y4R9|H0Y4R9_HUMAN Bromodomain and WD repeat-containin 3.8e-22 80.4 6.5 2.8e-09 39.6 0.1 5.0 4 tr|M0R317|M0R317_HUMAN Striatin-4 (Fragment) OS=Homo sapie 4.9e-22 80.0 16.7 0.00024 24.0 0.5 7.3 7 sp|Q8TEB1-2|DCA11_HUMAN Isoform 2 of DDB1- and CUL4-associa 7.4e-22 79.4 16.7 0.00025 24.0 0.5 7.3 6 sp|Q8TEB1|DCA11_HUMAN DDB1- and CUL4-associated factor 11 7.5e-22 79.4 6.1 1e-05 28.3 0.1 6.6 4 sp|Q8N5D0-4|WDTC1_HUMAN Isoform 4 of WD and tetratricopepti 7.7e-22 79.4 6.1 1e-05 28.3 0.1 6.6 4 sp|Q8N5D0|WDTC1_HUMAN WD and tetratricopeptide repeats pr 7.8e-22 79.4 7.1 0.0011 21.9 0.1 7.4 5 sp|Q5JSH3-2|WDR44_HUMAN Isoform 2 of WD repeat-containing p 9.2e-22 79.1 12.7 2.4e-06 30.4 0.1 6.3 5 sp|Q13216|ERCC8_HUMAN DNA excision repair protein ERCC-8 9.9e-22 79.0 4.5 0.2 14.8 0.0 7.6 6 sp|Q8NHY2-4|RFWD2_HUMAN Isoform 4 of E3 ubiquitin-protein l 1e-21 79.0 4.5 0.2 14.8 0.0 7.6 6 sp|Q8NHY2-2|RFWD2_HUMAN Isoform 2 of E3 ubiquitin-protein l 1.1e-21 78.9 2.6 0.00015 24.7 0.0 6.2 5 sp|O43684-2|BUB3_HUMAN Isoform 2 of Mitotic checkpoint pro 1.2e-21 78.8 2.6 0.00015 24.7 0.0 6.2 5 sp|O43684|BUB3_HUMAN Mitotic checkpoint protein BUB3 OS= 1.3e-21 78.7 4.5 0.21 14.7 0.0 7.6 6 sp|Q8NHY2|RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2 O 1.4e-21 78.5 9.4 1.2e-05 28.1 0.5 4.1 3 tr|H0YA24|H0YA24_HUMAN Pleiotropic regulator 1 (Fragment) 1.5e-21 78.5 33.2 0.00013 24.8 0.3 11.8 7 sp|Q8TEQ6|GEMI5_HUMAN Gem-associated protein 5 OS=Homo sa 2e-21 78.0 1.1 0.00019 24.4 0.1 5.0 4 tr|H3BPT1|H3BPT1_HUMAN Target of rapamycin complex subunit 2.3e-21 77.9 1.9 0.00023 24.1 0.0 6.1 4 sp|P57737-2|CORO7_HUMAN Isoform 2 of Coronin-7 OS=Homo sapi 2.7e-21 77.7 0.9 0.00022 24.2 0.1 5.0 4 sp|Q9BVC4-4|LST8_HUMAN Isoform 3 of Target of rapamycin co 2.8e-21 77.6 8.8 5.7e-06 29.2 0.3 6.5 5 tr|H0YEF1|H0YEF1_HUMAN Jouberin (Fragment) OS=Homo sapiens 2.9e-21 77.5 31.0 0.11 15.6 0.1 10.5 8 tr|K7EIK7|K7EIK7_HUMAN Echinoderm microtubule-associated p 3.3e-21 77.4 3.1 3.9e-07 32.8 0.0 3.1 3 tr|H0YEU5|H0YEU5_HUMAN Histone-binding protein RBBP4 (Frag 3.3e-21 77.4 3.1 4.2e-07 32.8 0.0 3.3 3 tr|B4DRT0|B4DRT0_HUMAN Histone-binding protein RBBP4 OS=Ho 3.4e-21 77.3 13.5 0.006 19.6 0.0 6.9 6 sp|O43379-2|WDR62_HUMAN Isoform 2 of WD repeat-containing p 3.6e-21 77.2 7.4 0.0013 21.7 0.0 7.8 7 tr|E7EQK3|E7EQK3_HUMAN WD repeat-containing protein 49 OS= 4.2e-21 77.1 7.4 0.0014 21.6 0.0 7.8 7 tr|H0Y8A5|H0Y8A5_HUMAN WD repeat-containing protein 49 (Fr 4.5e-21 77.0 7.5 4.4e-07 32.7 0.0 4.1 3 tr|H0YCT5|H0YCT5_HUMAN Histone-binding protein RBBP4 (Frag 5e-21 76.8 6.8 0.00041 23.3 0.0 6.4 6 tr|H0Y500|H0Y500_HUMAN Bromodomain and WD repeat-containin 5.2e-21 76.8 8.2 7.3e-06 28.8 0.3 6.4 5 tr|H0Y343|H0Y343_HUMAN Jouberin (Fragment) OS=Homo sapiens 6.2e-21 76.5 18.8 0.029 17.4 0.3 7.4 7 tr|B4DE62|B4DE62_HUMAN Transducin-like enhancer protein 2 6.7e-21 76.4 7.2 8.2e-07 31.8 0.0 4.6 4 tr|H0YDK2|H0YDK2_HUMAN Histone-binding protein RBBP4 (Frag 7.7e-21 76.2 0.2 0.013 18.6 0.0 8.7 6 sp|Q96MT7|WDR52_HUMAN WD repeat-containing protein 52 OS= 7.9e-21 76.2 18.9 0.00061 22.7 0.1 7.5 5 sp|Q9Y4E6-2|WDR7_HUMAN Isoform 2 of WD repeat-containing p 8.3e-21 76.1 10.9 4.9e-05 26.2 0.6 7.2 5 sp|O95170|CDRT1_HUMAN CMT1A duplicated region transcript 9e-21 76.0 10.8 8e-05 25.5 0.0 5.2 5 tr|F5H8J8|F5H8J8_HUMAN Guanine nucleotide-binding protein 9.2e-21 76.0 10.3 1.7e-06 30.8 1.2 6.5 4 sp|Q96P53|WDFY2_HUMAN WD repeat and FYVE domain-containin 9.2e-21 76.0 18.9 0.00062 22.7 0.1 7.5 5 sp|Q9Y4E6|WDR7_HUMAN WD repeat-containing protein 7 OS=H 1.3e-20 75.5 24.8 0.00056 22.9 0.2 8.4 6 tr|G3V1D0|G3V1D0_HUMAN Echinoderm microtubule associated p 1.3e-20 75.5 15.5 2.1e-06 30.6 0.1 5.8 4 tr|H0Y811|H0Y811_HUMAN Sperm-associated antigen 16 protein 1.4e-20 75.4 6.8 0.00049 23.0 0.0 6.4 6 tr|H0Y5I9|H0Y5I9_HUMAN Bromodomain and WD repeat-containin 1.6e-20 75.2 24.8 0.00057 22.8 0.2 8.4 6 tr|H0Y3M3|H0Y3M3_HUMAN Echinoderm microtubule-associated p 1.6e-20 75.2 9.2 4.3e-08 35.9 0.3 4.7 4 tr|K7EIR0|K7EIR0_HUMAN WD repeat-containing protein 18 OS= 1.7e-20 75.2 24.8 0.00058 22.8 0.2 8.4 6 sp|Q32P44-2|EMAL3_HUMAN Isoform 2 of Echinoderm microtubule 1.8e-20 75.0 9.6 0.0024 20.8 0.1 7.3 6 tr|H3BS99|H3BS99_HUMAN Zinc finger protein 106 (Fragment) 2.2e-20 74.8 9.2 4.6e-08 35.8 0.3 4.7 4 sp|Q9BV38|WDR18_HUMAN WD repeat-containing protein 18 OS= 2.9e-20 74.4 2.6 0.0061 19.6 0.1 7.3 6 sp|Q9H2Y7|ZN106_HUMAN Zinc finger protein 106 OS=Homo sap 3e-20 74.3 11.5 3.8e-07 32.9 0.1 5.6 4 tr|F5GXB6|F5GXB6_HUMAN WD repeat and SOCS box-containing p 4.1e-20 73.9 6.8 0.0006 22.8 0.0 6.5 6 tr|H0Y463|H0Y463_HUMAN Bromodomain and WD repeat-containin 4.3e-20 73.9 0.7 3.8e-06 29.7 0.0 3.6 3 sp|Q676U5-3|A16L1_HUMAN Isoform 3 of Autophagy-related prot 6.8e-20 73.2 2.6 0.00019 24.4 0.0 5.4 5 tr|H0Y4A7|H0Y4A7_HUMAN Bromodomain and WD repeat-containin 8.2e-20 73.0 2.2 1.5e-07 34.1 0.1 3.3 3 tr|B4DFS1|B4DFS1_HUMAN WD repeat and SOCS box-containing p 8.4e-20 72.9 8.9 0.0033 20.4 0.1 7.2 6 tr|E9PE29|E9PE29_HUMAN Zinc finger protein 106 OS=Homo sap 9.3e-20 72.8 0.0 2.9e-09 39.6 0.0 2.1 2 tr|F8VX21|F8VX21_HUMAN POC1 centriolar protein homolog B O 9.7e-20 72.7 8.3 1.3e-05 28.1 0.3 6.3 5 sp|Q8N157-2|AHI1_HUMAN Isoform 2 of Jouberin OS=Homo sapie 1e-19 72.7 11.0 7.2e-05 25.7 0.6 7.1 5 sp|Q5XX13-4|FBW10_HUMAN Isoform 4 of F-box/WD repeat-contai 1e-19 72.6 11.0 7.2e-05 25.7 0.6 7.1 5 sp|Q5XX13|FBW10_HUMAN F-box/WD repeat-containing protein 1.1e-19 72.6 11.0 7.3e-05 25.7 0.6 7.1 5 sp|Q5XX13-2|FBW10_HUMAN Isoform 2 of F-box/WD repeat-contai 1.2e-19 72.4 2.7 0.029 17.4 0.0 6.9 6 sp|A6NGE4|DC8L1_HUMAN DDB1- and CUL4-associated factor 8- 1.3e-19 72.3 3.5 1.8e-07 33.9 0.1 3.8 3 tr|B4DPV6|B4DPV6_HUMAN WD repeat and SOCS box-containing p 1.4e-19 72.2 16.3 1.9e-06 30.7 0.1 6.3 4 tr|B3KPW7|B3KPW7_HUMAN DNA excision repair protein ERCC-8 1.5e-19 72.1 6.0 0.00028 23.8 0.0 4.2 4 tr|C9JC24|C9JC24_HUMAN WD repeat-containing protein 48 (Fr 1.7e-19 72.0 13.4 2.7e-08 36.5 0.0 9.1 6 sp|Q8NI36|WDR36_HUMAN WD repeat-containing protein 36 OS= 2e-19 71.8 8.3 5.5e-05 26.0 0.1 4.6 4 sp|Q9BQ67|GRWD1_HUMAN Glutamate-rich WD repeat-containing 2e-19 71.8 8.7 7.8e-07 31.9 0.0 4.3 4 tr|C9J8B4|C9J8B4_HUMAN pre-mRNA 3' end-processing protein 2e-19 71.7 11.9 6.7e-05 25.8 0.2 4.1 3 tr|H0Y8R5|H0Y8R5_HUMAN Guanine nucleotide-binding protein 2.1e-19 71.7 14.1 0.00014 24.7 0.6 6.5 5 sp|Q8IWB7|WDFY1_HUMAN WD repeat and FYVE domain-containin 2.1e-19 71.7 18.8 0.049 16.7 0.3 7.5 7 sp|Q04725-2|TLE2_HUMAN Isoform 2 of Transducin-like enhanc 2.4e-19 71.5 14.5 2.3e-06 30.4 0.1 7.8 6 sp|Q8IWA0|WDR75_HUMAN WD repeat-containing protein 75 OS= 2.6e-19 71.4 27.1 0.0035 20.3 0.1 7.0 6 sp|P55735|SEC13_HUMAN Protein SEC13 homolog OS=Homo sapie 2.8e-19 71.3 3.0 0.00012 25.0 0.0 5.2 5 tr|J3QT28|J3QT28_HUMAN Mitotic checkpoint protein BUB3 (Fr 2.9e-19 71.2 8.7 1.5e-05 27.9 0.3 6.3 5 sp|Q8N157|AHI1_HUMAN Jouberin OS=Homo sapiens GN=AHI1 PE 2.9e-19 71.2 5.6 1.5e-05 27.9 0.4 5.6 4 tr|G8JLN6|G8JLN6_HUMAN Jouberin OS=Homo sapiens GN=AHI1 PE 3.6e-19 71.0 0.8 0.00014 24.8 0.1 4.2 4 tr|H3BR25|H3BR25_HUMAN Target of rapamycin complex subunit 4.4e-19 70.6 18.1 0.035 17.2 0.8 7.3 7 tr|B3KQ29|B3KQ29_HUMAN Transducin-like enhancer protein 4 5.2e-19 70.4 7.1 1.8e-06 30.8 0.0 4.1 3 tr|F5H103|F5H103_HUMAN Proteasomal ATPase-associated facto 5.6e-19 70.3 10.0 9.6e-07 31.6 0.1 5.8 4 sp|O75717|WDHD1_HUMAN WD repeat and HMG-box DNA-binding p 6e-19 70.2 26.0 0.0033 20.4 0.1 7.0 6 sp|P55735-2|SEC13_HUMAN Isoform 2 of Protein SEC13 homolog 6.2e-19 70.2 4.1 1.4e-07 34.3 0.1 3.5 3 sp|Q9Y6I7-4|WSB1_HUMAN Isoform 4 of WD repeat and SOCS box 6.5e-19 70.1 7.1 1.9e-06 30.7 0.0 4.1 3 tr|F5H3I1|F5H3I1_HUMAN Proteasomal ATPase-associated facto 7e-19 70.0 18.4 0.03 17.4 1.3 7.3 7 tr|H0YNI7|H0YNI7_HUMAN Transducin-like enhancer protein 3 7.3e-19 70.0 4.9 7.2e-08 35.2 0.1 3.6 3 tr|C9JYB3|C9JYB3_HUMAN WD repeat and HMG-box DNA-binding p 8e-19 69.8 27.3 0.0042 20.1 0.1 7.0 6 tr|B4DXJ1|B4DXJ1_HUMAN Protein SEC13 homolog OS=Homo sapie 9e-19 69.7 18.8 0.06 16.4 0.3 7.5 7 sp|Q04725|TLE2_HUMAN Transducin-like enhancer protein 2 9.3e-19 69.6 18.8 0.061 16.4 0.3 7.5 7 tr|K7EMK7|K7EMK7_HUMAN Transducin-like enhancer protein 2 1.1e-18 69.4 19.8 0.0029 20.6 0.1 6.4 6 tr|A8MXL6|A8MXL6_HUMAN Protein SEC13 homolog OS=Homo sapie 1.4e-18 69.1 1.0 0.0032 20.4 0.0 6.3 5 sp|Q9BYB4|GNB1L_HUMAN Guanine nucleotide-binding protein 1.4e-18 69.1 12.3 3.4e-06 29.9 0.0 6.2 3 sp|Q9BRP4-2|PAAF1_HUMAN Isoform 2 of Proteasomal ATPase-ass 1.6e-18 68.9 17.0 0.0021 21.1 0.1 10.8 4 sp|Q9NNW5|WDR6_HUMAN WD repeat-containing protein 6 OS=H 1.7e-18 68.8 5.2 8.3e-05 25.5 0.0 6.6 6 sp|Q7Z5U6|WDR53_HUMAN WD repeat-containing protein 53 OS= 1.8e-18 68.7 12.3 3.6e-06 29.8 0.0 6.2 3 sp|Q9BRP4|PAAF1_HUMAN Proteasomal ATPase-associated facto 1.8e-18 68.7 12.3 3.6e-06 29.8 0.0 6.2 3 tr|F5H0C4|F5H0C4_HUMAN Proteasomal ATPase-associated facto 2.1e-18 68.5 0.2 0.026 17.6 0.0 8.2 5 sp|Q96MT7-2|WDR52_HUMAN Isoform 2 of WD repeat-containing p 2.4e-18 68.3 5.4 0.0049 19.9 0.0 5.6 5 sp|O43379-3|WDR62_HUMAN Isoform 3 of WD repeat-containing p 2.7e-18 68.1 11.5 2.3e-06 30.4 0.0 4.1 4 tr|Q5JP02|Q5JP02_HUMAN Histone-binding protein RBBP7 (Frag 2.9e-18 68.1 9.5 0.0041 20.1 0.1 5.9 5 tr|G3V4J7|G3V4J7_HUMAN DDB1- and CUL4-associated factor 5 2.9e-18 68.1 9.5 0.0041 20.1 0.1 5.9 5 sp|Q96JK2|DCAF5_HUMAN DDB1- and CUL4-associated factor 5 3.1e-18 68.0 3.2 0.034 17.2 0.0 7.0 5 sp|P0C7V8|DC8L2_HUMAN DDB1- and CUL4-associated factor 8- 3.9e-18 67.7 4.9 0.0057 19.7 0.0 4.7 4 tr|D6RHX7|D6RHX7_HUMAN Mitogen-activated protein kinase-bi 4.7e-18 67.4 3.2 0.001 22.1 0.0 5.6 5 sp|Q8IV35-2|WDR49_HUMAN Isoform 2 of WD repeat-containing p 4.7e-18 67.4 9.5 0.00047 23.1 0.1 5.3 4 sp|Q9NWT1|PK1IP_HUMAN p21-activated protein kinase-intera 5.2e-18 67.3 1.4 0.02 17.9 0.2 8.5 5 sp|Q96MR6|WDR65_HUMAN WD repeat-containing protein 65 OS= 6.7e-18 66.9 11.4 0.027 17.5 0.1 9.6 6 tr|F8W0U9|F8W0U9_HUMAN NACHT and WD repeat domain-containi 7.3e-18 66.8 7.4 0.00029 23.7 0.1 4.2 4 tr|H7C5J5|H7C5J5_HUMAN Guanine nucleotide-binding protein 9.2e-18 66.5 3.3 0.00014 24.8 0.2 5.1 3 tr|H3BRY3|H3BRY3_HUMAN Coronin OS=Homo sapiens GN=CORO1A P 9.6e-18 66.4 5.2 0.002 21.1 0.0 4.4 4 tr|H0YMF9|H0YMF9_HUMAN WD repeat-containing protein 61 OS= 1.1e-17 66.2 3.4 1.2e-06 31.3 0.1 3.7 3 tr|B4DGZ9|B4DGZ9_HUMAN DNA excision repair protein ERCC-8 1.6e-17 65.8 20.8 0.002 21.1 0.1 10.8 4 tr|E9PDU5|E9PDU5_HUMAN WD repeat-containing protein 6 OS=H 1.8e-17 65.6 9.9 4e-08 36.0 0.3 3.8 3 tr|U3KQC1|U3KQC1_HUMAN WD repeat-containing protein 18 (Fr 2e-17 65.5 12.4 4.3e-05 26.4 0.0 5.1 4 tr|C0H5X6|C0H5X6_HUMAN PEX7 protein OS=Homo sapiens GN=PEX 2.2e-17 65.3 2.1 0.014 18.5 0.0 7.2 5 sp|Q9H6Y2|WDR55_HUMAN WD repeat-containing protein 55 OS= 2.3e-17 65.2 11.6 0.001 22.0 0.1 6.9 5 sp|Q9BUR4|WAP53_HUMAN Telomerase Cajal body protein 1 OS= 2.4e-17 65.2 1.2 0.00019 24.4 0.0 5.1 3 tr|B3KSY4|B3KSY4_HUMAN Coronin OS=Homo sapiens GN=CORO7 PE 2.9e-17 64.9 3.5 0.00017 24.5 0.2 5.1 3 sp|P31146|COR1A_HUMAN Coronin-1A OS=Homo sapiens GN=CORO1 3.1e-17 64.8 14.4 0.024 17.7 0.1 10.2 5 tr|E9PBV1|E9PBV1_HUMAN NACHT and WD repeat domain-containi 3.4e-17 64.7 13.8 0.025 17.6 0.1 10.1 5 tr|C9J2Y8|C9J2Y8_HUMAN NACHT and WD repeat domain-containi 3.8e-17 64.5 3.3 2.6e-05 27.1 0.0 4.5 3 tr|B4DTL1|B4DTL1_HUMAN WD repeat and SOCS box-containing p 3.9e-17 64.5 18.1 0.07 16.2 0.8 7.5 7 sp|Q04727-2|TLE4_HUMAN Isoform 2 of Transducin-like enhanc 4.1e-17 64.4 18.1 0.07 16.2 0.8 7.4 7 tr|G8JLG4|G8JLG4_HUMAN Transducin-like enhancer protein 4 4.2e-17 64.4 9.0 0.053 16.6 0.1 7.5 6 sp|Q58WW2|DCAF6_HUMAN DDB1- and CUL4-associated factor 6 4.4e-17 64.3 4.8 7.5e-06 28.8 0.0 4.9 3 tr|G5E996|G5E996_HUMAN WD repeat domain 31, isoform CRA_c 4.7e-17 64.2 5.3 0.00038 23.4 0.2 5.1 3 tr|J3KSS5|J3KSS5_HUMAN Coronin OS=Homo sapiens GN=CORO6 PE 4.7e-17 64.2 5.3 0.00038 23.4 0.2 5.1 3 sp|Q6QEF8|CORO6_HUMAN Coronin-6 OS=Homo sapiens GN=CORO6 5.1e-17 64.1 9.1 0.054 16.6 0.1 7.6 6 sp|Q58WW2-2|DCAF6_HUMAN Isoform 2 of DDB1- and CUL4-associa 6.2e-17 63.9 18.1 0.075 16.1 0.8 7.5 7 tr|F8W6T6|F8W6T6_HUMAN Transducin-like enhancer protein 4 6.4e-17 63.8 3.0 7.3e-05 25.7 0.2 3.7 3 tr|H3BRJ0|H3BRJ0_HUMAN Coronin (Fragment) OS=Homo sapiens 8.1e-17 63.5 18.1 0.078 16.1 0.8 7.5 7 sp|Q04727|TLE4_HUMAN Transducin-like enhancer protein 4 9.8e-17 63.2 0.8 0.0022 21.0 0.0 6.2 5 tr|G3V201|G3V201_HUMAN HCG1985539, isoform CRA_e OS=Homo s 1e-16 63.2 9.1 0.059 16.5 0.1 7.5 6 sp|Q58WW2-3|DCAF6_HUMAN Isoform 3 of DDB1- and CUL4-associa 1e-16 63.2 14.1 0.028 17.5 0.1 10.0 5 sp|Q149M9|NWD1_HUMAN NACHT and WD repeat domain-containi 1.1e-16 63.1 1.0 2.1e-05 27.4 0.0 3.8 3 tr|B4DGB8|B4DGB8_HUMAN WD repeat and SOCS box-containing p 1.1e-16 63.1 6.2 1.4e-06 31.1 0.0 5.7 4 tr|H0Y9I6|H0Y9I6_HUMAN Intraflagellar transport protein 12 1.1e-16 63.1 10.3 3.5e-05 26.7 0.1 5.0 4 tr|Q4VXH1|Q4VXH1_HUMAN F-box/WD repeat-containing protein 1.1e-16 63.1 18.1 0.082 16.0 0.8 7.5 7 sp|Q04727-3|TLE4_HUMAN Isoform 3 of Transducin-like enhanc 1.2e-16 63.0 18.1 0.082 16.0 0.8 7.5 7 tr|F8W9R0|F8W9R0_HUMAN Transducin-like enhancer protein 4 1.2e-16 63.0 6.2 0.01 18.9 0.2 8.8 4 sp|Q96MR6-2|WDR65_HUMAN Isoform 2 of WD repeat-containing p 1.5e-16 62.7 12.0 6.8e-05 25.8 0.6 6.1 4 sp|Q5XX13-3|FBW10_HUMAN Isoform 3 of F-box/WD repeat-contai 1.5e-16 62.6 3.7 2.6e-05 27.1 0.0 4.5 3 sp|Q9Y6I7-3|WSB1_HUMAN Isoform 3 of WD repeat and SOCS box 1.8e-16 62.4 6.1 0.0013 21.7 0.0 5.5 5 tr|H0YL98|H0YL98_HUMAN DDB1- and CUL4-associated factor 11 2.1e-16 62.2 8.7 0.001 22.1 0.1 6.3 4 sp|Q5JSH3-4|WDR44_HUMAN Isoform 4 of WD repeat-containing p 2.5e-16 61.9 1.6 7.4e-05 25.6 0.0 3.1 3 tr|F8VSE4|F8VSE4_HUMAN WD repeat domain-containing protein 2.7e-16 61.8 8.3 6.8e-05 25.7 0.3 8.2 4 sp|Q8TBY9-2|WDR66_HUMAN Isoform 2 of WD repeat-containing p 3.1e-16 61.7 19.0 0.073 16.2 1.3 7.5 7 tr|F5H7D6|F5H7D6_HUMAN Transducin-like enhancer protein 3 3.6e-16 61.4 5.9 3.8e-05 26.5 0.2 6.9 4 sp|Q92466|DDB2_HUMAN DNA damage-binding protein 2 OS=Hom 3.7e-16 61.4 19.0 0.075 16.1 1.3 7.5 7 tr|H0YNT2|H0YNT2_HUMAN Transducin-like enhancer protein 3 3.8e-16 61.4 3.7 4.9e-05 26.2 0.0 3.2 3 tr|F6X3N5|F6X3N5_HUMAN Guanine nucleotide-binding protein 3.8e-16 61.4 12.5 1.1e-05 28.2 0.0 8.0 6 sp|Q9HBG6|IF122_HUMAN Intraflagellar transport protein 12 3.9e-16 61.3 12.5 1.1e-05 28.2 0.0 8.0 6 sp|Q9HBG6-2|IF122_HUMAN Isoform 2 of Intraflagellar transpo 4.8e-16 61.1 1.4 0.0002 24.3 0.2 4.1 3 tr|D6R997|D6R997_HUMAN Coatomer subunit beta' (Fragment) O 5.3e-16 60.9 10.8 0.00094 22.1 0.1 6.8 5 tr|E9PMG4|E9PMG4_HUMAN Telomerase Cajal body protein 1 OS= 5.9e-16 60.8 2.8 4.6e-05 26.3 0.1 3.8 3 tr|H0YIE8|H0YIE8_HUMAN WD repeat domain-containing protein 6.1e-16 60.7 19.0 0.081 16.0 1.3 7.5 7 sp|Q04726-2|TLE3_HUMAN Isoform 2 of Transducin-like enhanc 6.3e-16 60.7 19.0 0.081 16.0 1.3 7.5 7 tr|F8W964|F8W964_HUMAN Transducin-like enhancer protein 3 6.4e-16 60.7 19.0 0.081 16.0 1.3 7.5 7 tr|F8W8S3|F8W8S3_HUMAN Transducin-like enhancer protein 3 6.4e-16 60.6 19.0 0.081 16.0 1.3 7.5 7 sp|Q04726-3|TLE3_HUMAN Isoform 3 of Transducin-like enhanc 6.6e-16 60.6 1.1 9e-09 38.0 0.6 2.4 2 tr|D6R909|D6R909_HUMAN Guanine nucleotide-binding protein 6.7e-16 60.6 19.0 0.082 16.0 1.3 7.5 7 tr|Q6PI57|Q6PI57_HUMAN TLE3 protein OS=Homo sapiens GN=TLE 6.7e-16 60.6 19.0 0.082 16.0 1.3 7.5 7 sp|Q04726-5|TLE3_HUMAN Isoform 5 of Transducin-like enhanc 7e-16 60.5 19.0 0.082 16.0 1.3 7.5 7 sp|Q04726-4|TLE3_HUMAN Isoform 4 of Transducin-like enhanc 7e-16 60.5 19.0 0.082 16.0 1.3 7.5 7 sp|Q04726|TLE3_HUMAN Transducin-like enhancer protein 3 7.1e-16 60.5 19.0 0.082 16.0 1.3 7.5 7 tr|H0YKT5|H0YKT5_HUMAN Transducin-like enhancer protein 3 7.4e-16 60.5 19.0 0.083 16.0 1.3 7.5 7 tr|H0YKN8|H0YKN8_HUMAN Transducin-like enhancer protein 3 7.7e-16 60.4 19.0 0.083 16.0 1.3 7.5 7 tr|H0YL70|H0YL70_HUMAN Transducin-like enhancer protein 3 7.8e-16 60.4 18.2 0.078 16.1 0.8 7.5 7 sp|Q04724|TLE1_HUMAN Transducin-like enhancer protein 1 7.9e-16 60.4 4.2 0.00015 24.7 0.1 4.2 4 tr|C9JTS3|C9JTS3_HUMAN Angio-associated migratory cell pro 8.4e-16 60.3 9.8 1e-05 28.3 0.0 7.8 5 sp|Q9HBG6-3|IF122_HUMAN Isoform 3 of Intraflagellar transpo 9.9e-16 60.1 2.7 9.4e-08 34.8 0.1 3.4 3 sp|P43034-2|LIS1_HUMAN Isoform 2 of Platelet-activating fa 1e-15 60.0 6.6 0.00038 23.4 0.2 4.4 3 sp|Q6QEF8-5|CORO6_HUMAN Isoform 5 of Coronin-6 OS=Homo sapi 1.1e-15 60.0 6.9 0.00034 23.5 0.2 4.2 3 tr|J3QLV6|J3QLV6_HUMAN Coronin OS=Homo sapiens GN=CORO6 PE 1.2e-15 59.8 3.2 0.024 17.7 0.0 9.0 4 sp|B1ANS9|WDR64_HUMAN WD repeat-containing protein 64 OS= 1.3e-15 59.7 7.7 0.0013 21.7 0.0 5.8 4 sp|Q9HAD4|WDR41_HUMAN WD repeat-containing protein 41 OS= 1.4e-15 59.6 8.2 8.6e-05 25.4 0.3 8.1 4 sp|Q8TBY9|WDR66_HUMAN WD repeat-containing protein 66 OS= 1.6e-15 59.4 0.2 2.4e-05 27.2 0.0 3.9 3 tr|H0YFG0|H0YFG0_HUMAN Autophagy-related protein 16-2 (Fra 1.7e-15 59.3 8.1 0.0011 22.0 0.0 5.4 4 tr|H0YAA3|H0YAA3_HUMAN WD repeat-containing protein 41 (Fr 1.7e-15 59.3 16.3 6.4e-05 25.8 0.6 6.4 4 tr|H0Y626|H0Y626_HUMAN Uncharacterized protein OS=Homo sap 2.1e-15 59.1 0.4 3.6e-07 33.0 0.0 2.2 2 tr|F5H3E9|F5H3E9_HUMAN Proteasomal ATPase-associated facto 2.5e-15 58.8 1.1 1.3e-06 31.2 0.1 4.7 3 tr|I3L167|I3L167_HUMAN Coronin OS=Homo sapiens GN=CORO7-PA 2.5e-15 58.8 13.3 1.2e-05 28.2 0.0 8.0 6 sp|Q9HBG6-5|IF122_HUMAN Isoform 5 of Intraflagellar transpo 2.5e-15 58.8 14.7 0.00015 24.6 0.3 5.6 4 sp|Q6PJI9-2|WDR59_HUMAN Isoform 2 of WD repeat-containing p 2.6e-15 58.7 1.7 0.00066 22.6 0.1 5.1 3 sp|Q92828|COR2A_HUMAN Coronin-2A OS=Homo sapiens GN=CORO2 2.9e-15 58.6 10.7 7.7e-05 25.6 0.0 6.1 4 sp|Q53HC9|TSSC1_HUMAN Protein TSSC1 OS=Homo sapiens GN=TS 3e-15 58.5 12.1 0.046 16.8 0.1 6.9 5 sp|Q9NW82|WDR70_HUMAN WD repeat-containing protein 70 OS= 3.4e-15 58.4 15.6 0.00011 25.1 0.1 6.5 4 sp|Q9UKT8|FBXW2_HUMAN F-box/WD repeat-containing protein 3.4e-15 58.3 0.3 0.0001 25.2 0.0 4.3 4 tr|B4DDM6|B4DDM6_HUMAN Mitotic checkpoint protein BUB3 OS= 3.5e-15 58.3 1.0 1.8e-05 27.6 0.0 4.2 3 tr|D6RD66|D6RD66_HUMAN WD repeat-containing protein 1 (Fra 3.6e-15 58.3 12.3 1.8e-05 27.6 0.2 6.4 5 sp|Q96S15-2|WDR24_HUMAN Isoform 2 of WD repeat-containing p 3.6e-15 58.3 2.8 0.00018 24.4 0.3 4.0 3 tr|H7C3Y7|H7C3Y7_HUMAN Neurobeachin-like protein 2 (Fragme 3.6e-15 58.3 15.3 0.58 13.3 0.0 10.6 5 sp|Q969X6-3|CIR1A_HUMAN Isoform 3 of Cirhin OS=Homo sapiens 5.1e-15 57.8 11.4 0.52 13.5 0.0 9.5 5 sp|Q969X6-2|CIR1A_HUMAN Isoform 2 of Cirhin OS=Homo sapiens 5.5e-15 57.7 13.8 0.67 13.1 0.0 10.4 4 tr|H3BSH7|H3BSH7_HUMAN Cirhin (Fragment) OS=Homo sapiens G 5.6e-15 57.7 10.6 1.1e-05 28.3 0.0 7.8 5 tr|E7EQF4|E7EQF4_HUMAN Intraflagellar transport protein 12 5.7e-15 57.7 13.3 0.086 15.9 2.0 6.6 6 sp|Q5XUX1-3|FBXW9_HUMAN Isoform 3 of F-box/WD repeat-contai 6.4e-15 57.5 12.3 8.4e-05 25.5 0.0 6.5 4 tr|A8MUM1|A8MUM1_HUMAN Protein TSSC1 OS=Homo sapiens GN=TS 6.9e-15 57.4 1.3 0.011 18.8 0.0 4.1 3 tr|H7C0R2|H7C0R2_HUMAN Angio-associated migratory cell pro 6.9e-15 57.4 13.2 0.09 15.9 2.0 6.6 6 sp|Q5XUX1-2|FBXW9_HUMAN Isoform 2 of F-box/WD repeat-contai 7.5e-15 57.3 0.6 6.4e-05 25.8 0.0 5.3 4 sp|Q86W42-3|THOC6_HUMAN Isoform 3 of THO complex subunit 6 7.8e-15 57.2 1.2 0.0015 21.5 0.0 4.6 4 sp|Q96KV7-10|WDR90_HUMAN Isoform 2 of WD repeat-containing p 7.9e-15 57.2 7.7 2.2e-06 30.5 0.0 5.4 2 sp|Q9BRP4-3|PAAF1_HUMAN Isoform 3 of Proteasomal ATPase-ass 8.3e-15 57.1 13.2 0.093 15.8 2.0 6.6 6 sp|Q5XUX1|FBXW9_HUMAN F-box/WD repeat-containing protein 9.5e-15 56.9 0.6 7.9e-05 25.6 0.0 5.6 4 sp|Q86W42|THOC6_HUMAN THO complex subunit 6 homolog OS=Ho 1e-14 56.8 0.2 7.3e-05 25.7 0.1 3.2 3 tr|H3BM50|H3BM50_HUMAN Target of rapamycin complex subunit 1.1e-14 56.8 26.0 0.071 16.2 1.9 7.7 6 sp|Q92636|FAN_HUMAN Protein FAN OS=Homo sapiens GN=NSMA 1.2e-14 56.6 15.4 0.65 13.2 0.0 10.4 5 sp|Q969X6|CIR1A_HUMAN Cirhin OS=Homo sapiens GN=CIRH1A PE 1.3e-14 56.6 0.1 3e-06 30.0 0.0 3.0 2 tr|C9JWF1|C9JWF1_HUMAN WD repeat-containing protein 31 (Fr 1.3e-14 56.5 5.9 0.0002 24.3 0.2 4.1 3 tr|E7EW44|E7EW44_HUMAN Coronin OS=Homo sapiens GN=CORO1B P 1.4e-14 56.4 26.0 0.074 16.1 1.9 7.7 6 sp|Q92636-2|FAN_HUMAN Isoform 2 of Protein FAN OS=Homo sa 1.5e-14 56.3 0.2 9.3e-05 25.3 0.1 3.4 3 tr|H3BPU5|H3BPU5_HUMAN Target of rapamycin complex subunit 1.7e-14 56.2 12.5 0.0087 19.1 0.0 5.0 4 tr|Q5JP01|Q5JP01_HUMAN Histone-binding protein RBBP7 (Frag 1.8e-14 56.0 0.2 3.3e-07 33.1 0.1 3.5 3 tr|I3L426|I3L426_HUMAN Coronin (Fragment) OS=Homo sapiens 1.9e-14 56.0 6.8 0.00019 24.3 0.2 4.1 3 tr|F5H390|F5H390_HUMAN Coronin OS=Homo sapiens GN=CORO1B P 2e-14 55.9 0.1 0.0017 21.3 0.0 5.8 4 sp|Q96KV7-7|WDR90_HUMAN Isoform 4 of WD repeat-containing p 2.1e-14 55.8 31.7 0.00076 22.4 1.9 6.6 5 sp|Q96EE3|SEH1_HUMAN Nucleoporin SEH1 OS=Homo sapiens GN 2.2e-14 55.8 1.3 7.1e-05 25.7 0.0 5.7 4 sp|Q86W42-2|THOC6_HUMAN Isoform 2 of THO complex subunit 6 2.4e-14 55.7 8.6 0.025 17.6 0.1 9.2 4 sp|Q149M9-3|NWD1_HUMAN Isoform 3 of NACHT and WD repeat do 3.2e-14 55.3 13.3 0.057 16.5 0.3 5.8 5 sp|Q04725-3|TLE2_HUMAN Isoform 3 of Transducin-like enhanc 3.5e-14 55.2 9.5 2.2e-05 27.3 0.2 6.2 4 sp|Q96S15|WDR24_HUMAN WD repeat-containing protein 24 OS= 3.5e-14 55.1 3.0 0.0032 20.4 0.2 3.6 3 sp|O60336-5|MABP1_HUMAN Isoform 5 of Mitogen-activated prot 3.6e-14 55.1 6.2 0.00011 25.1 0.3 3.4 3 tr|J3QRV4|J3QRV4_HUMAN Coronin (Fragment) OS=Homo sapiens 3.7e-14 55.1 15.4 0.42 13.8 0.5 8.1 6 tr|G3V3F1|G3V3F1_HUMAN Neural cell expressed, developmenta 3.8e-14 55.0 9.2 0.00079 22.4 0.0 6.5 4 tr|E9PKB8|E9PKB8_HUMAN WD repeat-containing protein KIAA18 3.8e-14 55.0 9.2 0.00079 22.4 0.0 6.5 4 sp|A6NE52-2|K1875_HUMAN Isoform 2 of WD repeat-containing p 4.7e-14 54.7 2.8 0.00049 23.0 0.3 4.4 3 sp|Q6ZNJ1-3|NBEL2_HUMAN Isoform 3 of Neurobeachin-like prot 4.8e-14 54.7 32.4 0.002 21.1 0.0 11.3 6 sp|Q8TDJ6|DMXL2_HUMAN DmX-like protein 2 OS=Homo sapiens 4.9e-14 54.7 32.4 0.002 21.1 0.0 11.3 6 sp|Q8TDJ6-3|DMXL2_HUMAN Isoform 3 of DmX-like protein 2 OS= 4.9e-14 54.7 2.8 0.0005 23.0 0.3 4.4 3 sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo 4.9e-14 54.7 4.9 0.00036 23.5 0.3 4.8 3 tr|H0Y764|H0Y764_HUMAN Neurobeachin-like protein 2 (Fragme 4.9e-14 54.7 8.1 0.00017 24.5 0.6 4.5 3 sp|Q9ULV4|COR1C_HUMAN Coronin-1C OS=Homo sapiens GN=CORO1 5.2e-14 54.6 7.6 0.0048 19.9 0.1 5.8 3 sp|Q6RI45-4|BRWD3_HUMAN Isoform 4 of Bromodomain and WD rep 5.2e-14 54.6 8.1 0.00017 24.5 0.6 4.5 3 sp|Q9ULV4-2|COR1C_HUMAN Isoform 2 of Coronin-1C OS=Homo sap 5.4e-14 54.6 0.6 4.3e-05 26.4 0.0 3.2 3 tr|J3QSX4|J3QSX4_HUMAN Mitotic checkpoint protein BUB3 OS= 5.8e-14 54.5 0.4 1.1e-06 31.4 0.0 3.5 3 sp|Q9C0J8-3|WDR33_HUMAN Isoform 3 of pre-mRNA 3' end proces 6.4e-14 54.3 7.8 0.00019 24.3 0.6 4.5 3 sp|Q9ULV4-3|COR1C_HUMAN Isoform 3 of Coronin-1C OS=Homo sap 7.6e-14 54.1 15.9 0.085 16.0 0.1 7.6 6 tr|C9JRL6|C9JRL6_HUMAN Echinoderm microtubule-associated p 8e-14 54.0 0.1 4.8e-06 29.4 0.0 2.1 2 tr|J3KRG6|J3KRG6_HUMAN WD repeat and SOCS box-containing p 9e-14 53.9 4.8 3.1e-05 26.9 0.2 6.0 3 sp|Q92466-4|DDB2_HUMAN Isoform D3 of DNA damage-binding pr 9.4e-14 53.8 3.9 0.4 13.8 0.1 6.6 5 sp|Q96EX3|WDR34_HUMAN WD repeat-containing protein 34 OS= 1.1e-13 53.6 2.4 5e-05 26.2 0.0 3.2 3 tr|F6UT28|F6UT28_HUMAN Guanine nucleotide-binding protein 1.2e-13 53.5 12.5 0.017 18.2 0.3 4.5 4 tr|K7EJR7|K7EJR7_HUMAN Transducin-like enhancer protein 2 1.3e-13 53.3 5.0 0.00046 23.1 0.3 4.7 3 sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like prot 1.3e-13 53.3 0.3 8.2e-07 31.8 0.0 2.4 2 tr|F5H5D4|F5H5D4_HUMAN Proteasomal ATPase-associated facto 1.6e-13 53.1 0.3 2.2e-05 27.3 0.1 2.9 2 tr|Q9NSS8|Q9NSS8_HUMAN Putative uncharacterized protein DK 1.6e-13 53.0 10.6 0.0029 20.6 0.8 6.2 5 sp|Q5QP82-2|DCA10_HUMAN Isoform 2 of DDB1- and CUL4-associa 1.7e-13 53.0 32.9 0.00094 22.2 1.9 6.6 5 sp|Q96EE3-1|SEH1_HUMAN Isoform B of Nucleoporin SEH1 OS=Ho 1.7e-13 52.9 17.5 0.42 13.8 0.5 8.1 6 sp|Q8NHV4|NEDD1_HUMAN Protein NEDD1 OS=Homo sapiens GN=NE 1.8e-13 52.9 8.2 0.0004 23.3 0.2 4.7 3 sp|Q9BR76|COR1B_HUMAN Coronin-1B OS=Homo sapiens GN=CORO1 1.9e-13 52.8 27.1 0.0016 21.5 0.0 10.0 5 sp|Q8TDJ6-2|DMXL2_HUMAN Isoform 2 of DmX-like protein 2 OS= 2.4e-13 52.5 10.6 0.0032 20.5 0.8 6.3 5 sp|Q5QP82|DCA10_HUMAN DDB1- and CUL4-associated factor 10 2.9e-13 52.3 4.4 0.0011 22.0 0.1 4.0 3 tr|Q8TBB7|Q8TBB7_HUMAN DDB1- and CUL4-associated factor 5 2.9e-13 52.2 2.5 0.022 17.8 0.0 4.4 3 tr|D6R9Q1|D6R9Q1_HUMAN Peptidylprolyl isomerase domain and 3.5e-13 52.0 7.1 1.6e-05 27.7 0.0 7.0 4 sp|Q562E7-2|WDR81_HUMAN Isoform 2 of WD repeat-containing p 3.9e-13 51.8 23.7 0.024 17.7 0.0 11.9 5 sp|Q9Y485|DMXL1_HUMAN DmX-like protein 1 OS=Homo sapiens 4.1e-13 51.8 10.6 0.0027 20.7 0.1 6.2 4 sp|Q64LD2|WDR25_HUMAN WD repeat-containing protein 25 OS= 4.3e-13 51.7 7.1 1.7e-05 27.7 0.0 7.0 4 sp|Q562E7-6|WDR81_HUMAN Isoform 6 of WD repeat-containing p 4.8e-13 51.5 0.0 4.6e-07 32.6 0.0 3.2 2 tr|D6RBT6|D6RBT6_HUMAN Coatomer subunit beta' (Fragment) O 4.9e-13 51.5 0.2 0.13 15.4 0.0 6.1 4 tr|H0YI59|H0YI59_HUMAN WD repeat-containing protein 90 (Fr 5.3e-13 51.4 0.6 0.019 18.0 0.1 4.5 3 sp|Q9UQ03-2|COR2B_HUMAN Isoform 2 of Coronin-2B OS=Homo sap 5.5e-13 51.4 7.1 1.7e-05 27.6 0.0 7.0 4 sp|Q562E7-5|WDR81_HUMAN Isoform 5 of WD repeat-containing p 5.6e-13 51.4 0.6 0.019 18.0 0.1 4.5 3 sp|Q9UQ03|COR2B_HUMAN Coronin-2B OS=Homo sapiens GN=CORO2 5.8e-13 51.3 5.1 0.023 17.7 0.1 4.9 4 sp|Q96JK2-2|DCAF5_HUMAN Isoform 2 of DDB1- and CUL4-associa 7.6e-13 50.9 10.2 1.3e-05 28.1 0.0 7.3 4 tr|B7Z6V3|B7Z6V3_HUMAN WD repeat-containing protein 81 OS= 8.3e-13 50.8 2.4 0.46 13.6 0.1 4.7 4 tr|H3BRD4|H3BRD4_HUMAN Zinc finger protein 106 (Fragment) 8.9e-13 50.7 24.7 0.024 17.7 0.0 11.8 5 tr|F5H269|F5H269_HUMAN DmX-like protein 1 OS=Homo sapiens 9.9e-13 50.6 10.4 1.3e-05 28.0 0.0 7.2 4 tr|E9PDG3|E9PDG3_HUMAN WD repeat-containing protein 81 OS= 1e-12 50.5 5.0 0.044 16.9 0.2 4.8 4 sp|O95170-2|CDRT1_HUMAN Isoform 2 of CMT1A duplicated regio 1.1e-12 50.4 1.9 0.00037 23.4 0.0 4.7 4 sp|Q8NFH4|NUP37_HUMAN Nucleoporin Nup37 OS=Homo sapiens G 1.3e-12 50.2 3.4 0.0007 22.5 0.0 6.2 3 tr|H0YLM8|H0YLM8_HUMAN DmX-like protein 2 (Fragment) OS=Ho 1.4e-12 50.1 6.6 2.2e-05 27.3 0.0 6.9 4 sp|Q562E7-3|WDR81_HUMAN Isoform 3 of WD repeat-containing p 1.7e-12 49.8 2.4 0.031 17.3 0.3 5.9 4 sp|O60336-4|MABP1_HUMAN Isoform 4 of Mitogen-activated prot 1.7e-12 49.8 9.5 5.6e-05 26.0 0.6 4.8 3 tr|C9JJ54|C9JJ54_HUMAN WD repeat and FYVE domain-containin 1.8e-12 49.7 0.7 4.7e-06 29.4 1.6 2.7 2 tr|Q5TFK1|Q5TFK1_HUMAN Eukaryotic translation initiation f 2.1e-12 49.5 7.4 0.019 18.0 0.0 6.6 4 tr|C9J1X0|C9J1X0_HUMAN Uncharacterized protein OS=Homo sap 2.5e-12 49.3 4.5 0.0011 21.9 0.0 4.9 3 tr|B4DT55|B4DT55_HUMAN WD repeat-containing protein 41 OS= 2.5e-12 49.3 9.2 0.0017 21.3 0.0 6.3 4 sp|A6NE52|K1875_HUMAN WD repeat-containing protein KIAA18 2.6e-12 49.2 0.4 0.0034 20.4 0.0 3.6 3 tr|H7C3R4|H7C3R4_HUMAN WD repeat-containing protein 62 (Fr 2.8e-12 49.1 0.3 4.8e-08 35.7 0.1 2.8 2 tr|C9JVF0|C9JVF0_HUMAN Transducin beta-like protein 2 OS=H 2.9e-12 49.1 7.4 0.02 18.0 0.0 6.6 4 sp|A4D1P6|WDR91_HUMAN WD repeat-containing protein 91 OS= 3.1e-12 49.0 2.3 2.5e-05 27.1 0.4 4.6 3 sp|Q969U6|FBXW5_HUMAN F-box/WD repeat-containing protein 3.2e-12 49.0 6.2 0.00049 23.0 0.0 8.2 3 sp|Q9P2S5|WRP73_HUMAN WD repeat-containing protein WRAP73 4e-12 48.6 23.2 0.00029 23.7 0.3 6.5 4 sp|Q6PJI9|WDR59_HUMAN WD repeat-containing protein 59 OS= 5.4e-12 48.2 0.1 1.4e-05 28.0 0.0 2.3 2 tr|H3BT67|H3BT67_HUMAN Katanin p80 WD40 repeat-containing 5.4e-12 48.2 3.1 0.00086 22.3 0.2 5.3 2 tr|B3KR43|B3KR43_HUMAN WD repeat-containing protein 20 OS= 5.9e-12 48.1 4.6 0.0017 21.3 0.0 5.8 3 sp|Q96MX6|WDR92_HUMAN WD repeat-containing protein 92 OS= 6e-12 48.1 15.3 0.24 14.5 0.1 8.3 5 tr|H0YN02|H0YN02_HUMAN WD repeat-containing protein 72 (Fr 6.3e-12 48.0 0.5 8.6e-05 25.4 0.1 2.3 2 tr|D6RF23|D6RF23_HUMAN Guanine nucleotide-binding protein 6.5e-12 48.0 16.1 0.0001 25.2 0.2 6.0 3 sp|Q99570|PI3R4_HUMAN Phosphoinositide 3-kinase regulator 6.7e-12 47.9 1.5 0.0026 20.8 0.2 4.7 3 tr|G5E9A7|G5E9A7_HUMAN Dystrophia myotonica WD repeat-cont 6.8e-12 47.9 17.2 0.0025 20.8 0.2 5.7 4 sp|P78406|RAE1L_HUMAN mRNA export factor OS=Homo sapiens 7.8e-12 47.7 1.5 0.0027 20.7 0.2 4.7 3 sp|Q09019|DMWD_HUMAN Dystrophia myotonica WD repeat-cont 9.1e-12 47.5 11.8 0.37 14.0 0.1 8.0 4 sp|Q3MJ13|WDR72_HUMAN WD repeat-containing protein 72 OS= 9.9e-12 47.4 11.8 0.37 13.9 0.1 7.9 4 tr|H0YKE0|H0YKE0_HUMAN WD repeat-containing protein 72 OS= 1e-11 47.4 3.8 0.02 18.0 0.0 6.8 3 sp|B1ANS9-2|WDR64_HUMAN Isoform 2 of WD repeat-containing p 1.1e-11 47.3 7.3 0.21 14.7 0.0 6.6 5 sp|Q58WW2-4|DCAF6_HUMAN Isoform 4 of DDB1- and CUL4-associa 1.2e-11 47.2 1.2 1.1e-05 28.3 0.1 2.6 2 tr|C9JGR9|C9JGR9_HUMAN WD repeat-containing protein 37 (Fr 1.3e-11 47.0 2.9 0.025 17.6 0.1 5.7 5 tr|F2Z305|F2Z305_HUMAN DDB1- and CUL4-associated factor 6 1.4e-11 47.0 3.2 2.1e-05 27.4 0.1 3.7 3 tr|M0QX71|M0QX71_HUMAN Glutamate-rich WD repeat-containing 1.4e-11 47.0 19.9 0.00028 23.8 0.2 7.0 4 sp|O15143|ARC1B_HUMAN Actin-related protein 2/3 complex s 1.4e-11 46.9 2.9 5.2e-05 26.1 0.0 6.4 3 sp|Q562E7|WDR81_HUMAN WD repeat-containing protein 81 OS= 1.5e-11 46.8 3.1 0.00099 22.1 0.2 5.2 2 sp|Q8TBZ3-4|WDR20_HUMAN Isoform 4 of WD repeat-containing p 1.5e-11 46.8 2.8 3e-05 26.9 0.1 3.1 3 tr|H0YLU1|H0YLU1_HUMAN Guanine nucleotide-binding protein 1.6e-11 46.7 3.1 0.001 22.0 0.2 5.2 2 sp|Q8TBZ3-5|WDR20_HUMAN Isoform 5 of WD repeat-containing p 1.6e-11 46.7 0.0 0.11 15.6 0.0 4.0 3 tr|I3L4T9|I3L4T9_HUMAN Cirhin (Fragment) OS=Homo sapiens G 1.7e-11 46.6 17.1 0.0031 20.5 0.2 5.8 4 tr|E9PQ57|E9PQ57_HUMAN mRNA export factor OS=Homo sapiens 1.8e-11 46.6 14.6 0.019 18.0 0.1 6.0 4 sp|P57775|FBXW4_HUMAN F-box/WD repeat-containing protein 1.8e-11 46.6 3.1 0.001 22.0 0.2 5.2 2 sp|Q8TBZ3-6|WDR20_HUMAN Isoform 6 of WD repeat-containing p 1.8e-11 46.6 8.2 0.022 17.8 0.1 6.0 3 tr|B4DJV5|B4DJV5_HUMAN Periodic tryptophan protein 1 homol 1.9e-11 46.5 15.4 0.00036 23.5 0.5 6.2 3 sp|Q86Y33-2|CD20B_HUMAN Isoform 2 of Cell division cycle pr 2e-11 46.5 12.2 0.36 14.0 0.1 7.8 4 tr|H0YLX4|H0YLX4_HUMAN WD repeat-containing protein 72 OS= 2.1e-11 46.4 2.5 0.074 16.1 0.0 4.5 3 tr|F5H7P7|F5H7P7_HUMAN Peptidylprolyl isomerase domain and 2.2e-11 46.3 1.2 0.00019 24.3 0.1 3.5 3 sp|Q9NZJ0-2|DTL_HUMAN Isoform 2 of Denticleless protein h 2.2e-11 46.3 17.9 0.002 21.1 1.8 6.9 4 sp|Q15061|WDR43_HUMAN WD repeat-containing protein 43 OS= 2.2e-11 46.3 1.3 3.8e-05 26.6 0.2 2.4 2 tr|H3BU76|H3BU76_HUMAN Coronin (Fragment) OS=Homo sapiens 2.4e-11 46.2 1.2 1.4e-05 27.9 0.1 2.5 2 tr|E7EQ49|E7EQ49_HUMAN WD repeat-containing protein 37 OS= 2.7e-11 46.0 2.5 0.078 16.1 0.0 4.5 3 sp|Q96BP3|PPWD1_HUMAN Peptidylprolyl isomerase domain and 2.8e-11 45.9 9.7 0.026 17.6 0.1 6.7 3 sp|Q13610|PWP1_HUMAN Periodic tryptophan protein 1 homol 2.9e-11 45.9 2.4 0.00074 22.5 0.2 4.4 2 tr|B3KPG5|B3KPG5_HUMAN WD repeat-containing protein 20 OS= 2.9e-11 45.9 3.4 0.0012 21.8 0.6 3.9 3 tr|K7EML4|K7EML4_HUMAN WD repeat-containing protein 18 (Fr 3.5e-11 45.7 3.1 0.0012 21.8 0.2 5.2 2 sp|Q8TBZ3-7|WDR20_HUMAN Isoform 7 of WD repeat-containing p 3.5e-11 45.7 0.0 3.3e-10 42.6 0.0 2.1 1 tr|H0YH33|H0YH33_HUMAN Serine-threonine kinase receptor-as 3.6e-11 45.6 3.5 0.0012 21.9 0.2 5.2 2 sp|Q8TBZ3|WDR20_HUMAN WD repeat-containing protein 20 OS= 3.8e-11 45.5 2.5 0.0042 20.1 0.1 3.6 3 tr|K7EQT1|K7EQT1_HUMAN Fizzy-related protein homolog OS=Ho 3.9e-11 45.5 3.5 0.0012 21.8 0.2 5.3 2 sp|Q8TBZ3-2|WDR20_HUMAN Isoform 2 of WD repeat-containing p 4e-11 45.5 3.6 8.4e-07 31.8 0.1 3.9 2 tr|C9JW18|C9JW18_HUMAN WD repeat and HMG-box DNA-binding p 4.1e-11 45.4 2.2 3.1e-05 26.8 0.5 2.6 2 tr|F8VSA4|F8VSA4_HUMAN Coronin (Fragment) OS=Homo sapiens 4.2e-11 45.4 2.2 3.1e-05 26.8 0.5 2.6 2 tr|F8VRE9|F8VRE9_HUMAN Coronin (Fragment) OS=Homo sapiens 4.6e-11 45.3 1.3 6e-05 25.9 0.2 2.6 2 tr|H3BSL1|H3BSL1_HUMAN Coronin (Fragment) OS=Homo sapiens 4.9e-11 45.2 2.2 3.3e-05 26.7 0.5 2.6 2 tr|F8VTT6|F8VTT6_HUMAN Coronin (Fragment) OS=Homo sapiens 5e-11 45.2 3.9 2.3e-05 27.2 0.0 3.7 3 tr|C9JVR6|C9JVR6_HUMAN Protein TSSC1 (Fragment) OS=Homo sa 5.3e-11 45.1 6.0 0.049 16.7 0.3 4.3 3 tr|G3V2V3|G3V2V3_HUMAN Protein NEDD1 (Fragment) OS=Homo sa 5.4e-11 45.1 12.7 0.00032 23.6 0.5 5.4 3 sp|Q86Y33-3|CD20B_HUMAN Isoform 3 of Cell division cycle pr 5.6e-11 45.0 12.4 0.039 17.0 0.1 5.8 3 sp|Q96FK6|WDR89_HUMAN WD repeat-containing protein 89 OS= 5.8e-11 45.0 1.0 0.00011 25.1 0.0 3.4 2 tr|D6REC9|D6REC9_HUMAN THO complex subunit 3 OS=Homo sapie 6.1e-11 44.9 2.2 3.7e-05 26.6 0.5 2.6 2 tr|F8VVB7|F8VVB7_HUMAN Coronin (Fragment) OS=Homo sapiens 6.3e-11 44.8 9.3 0.00022 24.1 1.9 3.3 3 tr|C9JEE7|C9JEE7_HUMAN WD repeat-containing protein 43 (Fr 7.3e-11 44.6 16.0 0.00036 23.5 0.5 6.2 3 sp|Q86Y33|CD20B_HUMAN Cell division cycle protein 20 homo 7.6e-11 44.6 0.1 0.006 19.6 0.0 5.2 3 sp|Q9HCU5|PREB_HUMAN Prolactin regulatory element-bindin 8.5e-11 44.4 11.3 1.5 12.0 0.0 7.6 4 sp|Q9P2H3|IFT80_HUMAN Intraflagellar transport protein 80 8.8e-11 44.4 16.7 0.00075 22.5 0.5 6.1 3 sp|Q92747|ARC1A_HUMAN Actin-related protein 2/3 complex s 9.7e-11 44.3 1.5 4.4e-05 26.4 0.0 3.3 2 tr|C9JZN1|C9JZN1_HUMAN Guanine nucleotide-binding protein 1.4e-10 43.8 2.3 0.023 17.7 0.1 4.5 3 tr|D6RIW8|D6RIW8_HUMAN WD repeat-containing protein 70 OS= 1.5e-10 43.7 9.6 6.2e-05 25.9 0.0 5.1 3 sp|O75530-2|EED_HUMAN Isoform 2 of Polycomb protein EED O 1.6e-10 43.6 1.3 9e-06 28.5 0.1 4.9 2 sp|Q8N5D0-5|WDTC1_HUMAN Isoform 5 of WD and tetratricopepti 1.6e-10 43.6 1.3 9e-06 28.5 0.1 4.9 2 sp|Q8N5D0-3|WDTC1_HUMAN Isoform 3 of WD and tetratricopepti 1.8e-10 43.4 1.8 5.3e-06 29.3 0.2 4.6 3 tr|H0YJS1|H0YJS1_HUMAN Echinoderm microtubule-associated p 1.8e-10 43.4 5.8 0.77 12.9 0.3 6.0 5 sp|Q8NFP9-2|NBEA_HUMAN Isoform 2 of Neurobeachin OS=Homo s 1.9e-10 43.3 0.4 4e-05 26.5 0.1 2.9 2 tr|B4DU75|B4DU75_HUMAN U3 small nucleolar RNA-associated p 2e-10 43.3 7.3 0.0081 19.2 0.1 5.6 4 sp|Q9H1Z4|WDR13_HUMAN WD repeat-containing protein 13 OS= 2.3e-10 43.1 0.9 0.31 14.2 0.0 6.7 3 tr|A5PKZ0|A5PKZ0_HUMAN IFT172 protein OS=Homo sapiens GN=I 2.4e-10 43.0 14.7 0.00051 23.0 0.5 4.6 3 tr|E9PF58|E9PF58_HUMAN Actin-related protein 2/3 complex s 2.6e-10 42.9 8.9 0.33 14.1 0.3 8.6 4 tr|D6R922|D6R922_HUMAN WD repeat-containing protein 36 OS= 2.9e-10 42.8 8.3 0.048 16.8 0.3 4.3 3 tr|G3V4L2|G3V4L2_HUMAN Protein NEDD1 (Fragment) OS=Homo sa 3.3e-10 42.6 2.4 2e-05 27.4 0.0 3.6 2 tr|J3KT03|J3KT03_HUMAN WD repeat and SOCS box-containing p 3.4e-10 42.5 5.9 0.95 12.6 0.1 6.6 4 tr|C9JPK3|C9JPK3_HUMAN Syntaxin-binding protein 5-like OS= 3.6e-10 42.4 0.2 0.01 18.9 0.0 3.5 2 tr|H3BTU6|H3BTU6_HUMAN Coronin (Fragment) OS=Homo sapiens 3.9e-10 42.4 0.1 3.4e-07 33.0 0.1 2.4 2 tr|H0Y9E1|H0Y9E1_HUMAN Intraflagellar transport protein 12 4.1e-10 42.3 11.4 5.8e-05 26.0 0.0 5.1 3 sp|O75530|EED_HUMAN Polycomb protein EED OS=Homo sapien 4.1e-10 42.3 2.0 5.4 10.3 0.1 6.8 5 sp|Q00005-6|2ABB_HUMAN Isoform 6 of Serine/threonine-prote 4.5e-10 42.2 1.5 0.0019 21.2 0.6 3.2 3 tr|F8W7Q3|F8W7Q3_HUMAN WD repeat-containing protein 48 OS= 5.3e-10 41.9 1.0 0.0094 19.0 0.5 3.6 2 tr|C9JAJ5|C9JAJ5_HUMAN Putative uncharacterized protein LO 5.3e-10 41.9 6.3 0.00061 22.7 0.0 3.6 2 tr|E7EVM5|E7EVM5_HUMAN DDB1- and CUL4-associated factor 13 5.3e-10 41.9 1.0 0.0094 19.0 0.5 3.6 2 sp|Q86TI4-2|WDR86_HUMAN Isoform 2 of WD repeat-containing p 5.5e-10 41.9 17.4 0.0019 21.2 2.0 6.2 3 sp|Q15291|RBBP5_HUMAN Retinoblastoma-binding protein 5 OS 6.1e-10 41.7 7.7 2.7 11.2 0.2 6.4 5 sp|Q8NHV4-2|NEDD1_HUMAN Isoform 2 of Protein NEDD1 OS=Homo 6.4e-10 41.7 4.1 9.3e-06 28.5 0.1 5.4 2 sp|Q8N5D0-6|WDTC1_HUMAN Isoform 6 of WD and tetratricopepti 6.5e-10 41.6 4.1 9.3e-06 28.5 0.1 5.4 2 sp|Q8N5D0-2|WDTC1_HUMAN Isoform 2 of WD and tetratricopepti 7e-10 41.5 18.4 0.0017 21.3 2.0 6.2 5 sp|Q15291-2|RBBP5_HUMAN Isoform 2 of Retinoblastoma-binding 7.1e-10 41.5 5.7 1.1 12.4 0.1 6.5 4 tr|C9JQS3|C9JQS3_HUMAN Syntaxin-binding protein 5-like (Fr 7.2e-10 41.5 4.0 0.0015 21.5 0.7 4.6 2 tr|H7BZA0|H7BZA0_HUMAN Neurobeachin-like protein 1 (Fragme 7.4e-10 41.5 22.5 0.0076 19.3 0.2 6.4 5 sp|Q12770-4|SCAP_HUMAN Isoform 4 of Sterol regulatory elem 7.8e-10 41.4 1.8 0.0077 19.3 0.1 3.1 2 tr|H0YGZ5|H0YGZ5_HUMAN Pre-mRNA-processing factor 19 (Frag 7.9e-10 41.4 4.4 5.6 10.2 0.1 6.8 5 sp|Q00005-2|2ABB_HUMAN Isoform 2 of Serine/threonine-prote 8.5e-10 41.3 22.5 0.0078 19.2 0.2 6.4 5 sp|Q12770-2|SCAP_HUMAN Isoform 2 of Sterol regulatory elem 8.6e-10 41.3 3.3 5.5 10.2 0.1 6.8 5 sp|Q00005|2ABB_HUMAN Serine/threonine-protein phosphatas 9.3e-10 41.2 3.5 5.1e-05 26.2 0.0 4.2 2 sp|O75530-3|EED_HUMAN Isoform 3 of Polycomb protein EED O 1.1e-09 40.9 0.9 0.53 13.5 0.0 5.8 4 sp|Q6RFH5|WDR74_HUMAN WD repeat-containing protein 74 OS= 1.3e-09 40.7 5.7 1.2 12.3 0.3 5.9 5 sp|Q8NFP9-3|NBEA_HUMAN Isoform 3 of Neurobeachin OS=Homo s 1.5e-09 40.5 11.0 0.2 14.8 0.1 7.6 4 tr|F5H7J5|F5H7J5_HUMAN Regulatory-associated protein of mT 1.5e-09 40.5 0.7 0.49 13.5 0.0 5.3 4 sp|Q6RFH5-2|WDR74_HUMAN Isoform 2 of WD repeat-containing p 1.6e-09 40.4 0.2 4.3e-09 39.0 0.2 1.8 1 tr|Q6ZW40|Q6ZW40_HUMAN POC1 centriolar protein homolog B O 1.9e-09 40.1 22.5 0.009 19.0 0.2 6.4 4 tr|F8W921|F8W921_HUMAN Sterol regulatory element-binding p 2.1e-09 40.0 0.0 3.5e-09 39.3 0.0 1.4 1 tr|H0YLA1|H0YLA1_HUMAN WD repeat-containing protein 61 (Fr 2.1e-09 40.0 3.4 6.5 10.0 0.1 6.8 5 sp|Q00005-4|2ABB_HUMAN Isoform 4 of Serine/threonine-prote 2.2e-09 40.0 0.1 3.4e-05 26.7 0.0 2.9 2 tr|C9JBE7|C9JBE7_HUMAN WD repeat-containing protein 53 OS= 2.2e-09 39.9 0.1 3.4e-05 26.7 0.0 2.9 2 tr|C9JJZ8|C9JJZ8_HUMAN WD repeat-containing protein 53 OS= 2.3e-09 39.9 16.7 8e-05 25.5 0.1 6.1 4 sp|Q9BQA1|MEP50_HUMAN Methylosome protein 50 OS=Homo sapi 2.3e-09 39.9 3.4 6.6 10.0 0.1 6.8 5 sp|Q00005-5|2ABB_HUMAN Isoform 5 of Serine/threonine-prote 2.4e-09 39.9 5.1 0.99 12.6 0.3 6.8 3 sp|Q9HBG6-4|IF122_HUMAN Isoform 4 of Intraflagellar transpo 2.7e-09 39.7 3.6 15 8.9 0.1 6.7 5 sp|P63151|2ABA_HUMAN Serine/threonine-protein phosphatas 3.2e-09 39.4 0.5 0.13 15.4 0.0 4.2 3 tr|J3KSI1|J3KSI1_HUMAN Cirhin (Fragment) OS=Homo sapiens G 3.3e-09 39.4 3.4 0.0007 22.5 0.6 3.5 3 tr|U3KQQ3|U3KQQ3_HUMAN WD repeat-containing protein 18 (Fr 3.3e-09 39.4 4.0 5.6 10.2 0.1 6.8 5 sp|Q00005-3|2ABB_HUMAN Isoform 3 of Serine/threonine-prote 3.6e-09 39.3 11.0 0.23 14.6 0.1 7.6 4 sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mT 4e-09 39.1 9.3 0.0011 21.9 0.2 3.8 3 tr|E9PPG9|E9PPG9_HUMAN mRNA export factor OS=Homo sapiens 4.1e-09 39.1 3.4 7.2 9.8 0.1 6.8 5 sp|Q00005-7|2ABB_HUMAN Isoform 7 of Serine/threonine-prote 4.4e-09 39.0 1.1 0.11 15.6 0.1 4.9 3 sp|Q8WUA4|TF3C2_HUMAN General transcription factor 3C pol 4.5e-09 39.0 6.4 0.1 15.7 0.0 5.2 3 sp|Q64LD2-2|WDR25_HUMAN Isoform 2 of WD repeat-containing p 4.6e-09 39.0 11.0 0.0019 21.2 0.1 5.6 2 tr|H3BLT2|H3BLT2_HUMAN WD repeat- and FYVE domain-containi 4.9e-09 38.9 0.2 0.0062 19.6 0.0 4.2 4 tr|G3V1J0|G3V1J0_HUMAN WD repeat domain 55, isoform CRA_b 5e-09 38.9 17.3 6.4e-05 25.8 0.1 6.1 3 tr|H0Y711|H0Y711_HUMAN Methylosome protein 50 (Fragment) O 5.2e-09 38.8 0.9 0.42 13.8 0.0 5.6 4 tr|E9PS41|E9PS41_HUMAN WD repeat-containing protein 74 OS= 5.6e-09 38.7 4.6 15 8.8 0.1 6.7 5 sp|P63151-2|2ABA_HUMAN Isoform 2 of Serine/threonine-prote 5.7e-09 38.7 0.0 0.005 19.9 0.0 4.5 2 tr|B5MC98|B5MC98_HUMAN Prolactin regulatory element-bindin 6.1e-09 38.6 0.7 2.1e-07 33.7 0.1 2.5 1 tr|I3L2Y6|I3L2Y6_HUMAN Coronin (Fragment) OS=Homo sapiens 6.3e-09 38.5 0.7 0.11 15.6 0.0 3.1 3 tr|C9IZR2|C9IZR2_HUMAN Intraflagellar transport protein 80 6.7e-09 38.4 11.8 0.95 12.6 0.1 7.3 4 tr|C9K0E4|C9K0E4_HUMAN Syntaxin-binding protein 5-like OS= 6.9e-09 38.4 1.6 0.05 16.7 0.0 5.1 3 tr|C9JYH8|C9JYH8_HUMAN WD repeat domain 45, isoform CRA_e 7.8e-09 38.2 22.5 0.012 18.7 0.2 6.4 4 sp|Q12770|SCAP_HUMAN Sterol regulatory element-binding p 8.1e-09 38.2 1.7 0.72 13.0 0.0 4.7 3 tr|H0Y978|H0Y978_HUMAN Intraflagellar transport protein 12 8.1e-09 38.2 11.8 0.98 12.6 0.1 7.3 4 tr|C9JCY1|C9JCY1_HUMAN Syntaxin-binding protein 5-like OS= 8.5e-09 38.1 0.2 0.043 16.9 0.0 4.2 3 tr|A6NM71|A6NM71_HUMAN WD repeat domain phosphoinositide-i 8.8e-09 38.1 2.0 2.4 11.4 0.2 5.9 4 tr|H0YAC6|H0YAC6_HUMAN Lipopolysaccharide-responsive and b 9.8e-09 37.9 0.9 0.014 18.5 0.1 2.2 2 tr|F8VV53|F8VV53_HUMAN Coronin (Fragment) OS=Homo sapiens 1.1e-08 37.8 1.5 0.057 16.5 0.0 5.2 3 sp|Q9Y484|WIPI4_HUMAN WD repeat domain phosphoinositide-i 1.1e-08 37.8 0.2 2.4e-08 36.7 0.2 1.6 1 tr|F8WDI9|F8WDI9_HUMAN Transducin beta-like protein 2 OS=H 1.2e-08 37.7 2.0 0.45 13.7 0.1 4.3 4 tr|B4DZ46|B4DZ46_HUMAN F-box/WD repeat-containing protein 1.2e-08 37.7 1.5 0.058 16.5 0.0 5.1 3 sp|Q9Y484-3|WIPI4_HUMAN Isoform 3 of WD repeat domain phosp 1.2e-08 37.6 19.9 0.00089 22.2 0.9 5.1 3 tr|K7ELV2|K7ELV2_HUMAN Nucleoporin SEH1 (Fragment) OS=Homo 1.3e-08 37.6 1.5 0.06 16.4 0.0 5.2 3 sp|Q9Y484-2|WIPI4_HUMAN Isoform 2 of WD repeat domain phosp 1.3e-08 37.5 13.8 2.8e-05 27.0 1.9 4.4 3 tr|H0YJX1|H0YJX1_HUMAN Echinoderm microtubule-associated p 1.6e-08 37.2 12.3 0.0004 23.3 0.9 4.1 3 tr|K7ENI5|K7ENI5_HUMAN Nucleoporin SEH1 (Fragment) OS=Homo 1.7e-08 37.2 5.1 0.013 18.5 0.2 3.3 3 tr|H3BR95|H3BR95_HUMAN WD repeat-containing protein 59 (Fr 1.7e-08 37.1 1.5 0.0017 21.3 0.7 2.7 2 tr|F8W9K4|F8W9K4_HUMAN WD repeat-containing protein 48 OS= 1.9e-08 37.0 1.8 0.0013 21.7 0.0 5.0 2 sp|Q96MX6-2|WDR92_HUMAN Isoform 2 of WD repeat-containing p 1.9e-08 37.0 1.3 0.075 16.1 0.0 3.2 3 tr|J3KTR0|J3KTR0_HUMAN Cirhin (Fragment) OS=Homo sapiens G 2.1e-08 36.9 7.9 0.018 18.1 0.1 4.5 3 tr|G3V4B8|G3V4B8_HUMAN WD repeat-containing protein 89 (Fr 2.3e-08 36.7 0.0 0.036 17.1 0.0 3.1 2 tr|D6RBG7|D6RBG7_HUMAN Coatomer subunit beta' (Fragment) O 2.4e-08 36.7 12.0 1.1 12.4 0.1 7.1 4 tr|E9PFI2|E9PFI2_HUMAN Syntaxin-binding protein 5-like OS= 2.4e-08 36.7 5.2 3.4 10.9 0.1 6.9 3 tr|B4DEY9|B4DEY9_HUMAN Intraflagellar transport protein 12 2.6e-08 36.6 0.3 7.3e-05 25.7 0.0 2.4 2 tr|H0YEI6|H0YEI6_HUMAN WD and tetratricopeptide repeats pr 2.8e-08 36.5 11.9 1.2 12.4 0.1 7.1 4 sp|Q9Y2K9|STB5L_HUMAN Syntaxin-binding protein 5-like OS= 3.1e-08 36.3 0.5 0.025 17.6 0.0 3.1 2 tr|D6RH33|D6RH33_HUMAN WD repeat-containing protein 41 (Fr 3.3e-08 36.3 0.3 0.035 17.2 0.0 3.5 2 tr|D6RBY6|D6RBY6_HUMAN WD repeat-containing protein 41 (Fr 3.4e-08 36.2 2.2 0.00015 24.7 0.0 4.0 2 tr|J3KTP2|J3KTP2_HUMAN WD repeat-containing protein WRAP73 3.4e-08 36.2 0.3 0.034 17.2 0.0 3.4 2 tr|B4DHS8|B4DHS8_HUMAN WD repeat-containing protein 41 OS= 3.5e-08 36.2 0.3 0.00042 23.2 0.0 2.5 2 tr|B4E2L4|B4E2L4_HUMAN WD repeat-containing protein 41 OS= 3.8e-08 36.1 0.0 0.025 17.6 0.0 2.9 2 tr|D6RB94|D6RB94_HUMAN WD repeat-containing protein 41 OS= 3.9e-08 36.0 0.8 4.9e-05 26.2 0.2 3.1 2 tr|C9J4Z7|C9J4Z7_HUMAN Actin-related protein 2/3 complex s 3.9e-08 36.0 0.0 3.8 10.7 0.0 6.3 3 sp|Q9Y5J1|UTP18_HUMAN U3 small nucleolar RNA-associated p 3.9e-08 36.0 0.4 2.1 11.6 0.0 3.6 3 sp|Q9BYB4-2|GNB1L_HUMAN Isoform 2 of Guanine nucleotide-bin 4e-08 36.0 0.1 0.025 17.6 0.0 2.9 2 tr|D6R9E7|D6R9E7_HUMAN WD repeat-containing protein 41 (Fr 4.1e-08 35.9 0.8 5.1e-05 26.2 0.2 3.1 2 tr|C9JEY1|C9JEY1_HUMAN Actin-related protein 2/3 complex s 4.3e-08 35.9 1.4 0.076 16.1 0.2 3.5 2 tr|B4E3S0|B4E3S0_HUMAN Coronin OS=Homo sapiens GN=CORO1C P 4.3e-08 35.9 0.5 0.0019 21.2 0.2 2.7 2 tr|D6R9F7|D6R9F7_HUMAN Mitogen-activated protein kinase-bi 4.6e-08 35.8 2.3 0.022 17.8 0.4 2.8 2 tr|K7EMB8|K7EMB8_HUMAN WD repeat-containing protein 7 (Fra 4.7e-08 35.8 3.1 0.0066 19.5 0.7 4.7 2 sp|Q6ZS30-1|NBEL1_HUMAN Isoform 1 of Neurobeachin-like prot 4.9e-08 35.7 1.7 1.1 12.5 0.4 5.6 2 sp|Q5VTH9|WDR78_HUMAN WD repeat-containing protein 78 OS= 5e-08 35.7 0.5 0.038 17.0 0.0 3.5 2 tr|D6RE66|D6RE66_HUMAN WD repeat-containing protein 41 (Fr 5e-08 35.7 3.9 0.00045 23.2 0.2 3.4 2 tr|F5H0F7|F5H0F7_HUMAN Proteasomal ATPase-associated facto 5.1e-08 35.7 0.0 0.027 17.5 0.0 2.8 2 tr|B4DK73|B4DK73_HUMAN WD repeat-containing protein 41 OS= 5.1e-08 35.6 0.4 2.1e-07 33.7 0.1 2.1 1 tr|I3L1M1|I3L1M1_HUMAN Coronin (Fragment) OS=Homo sapiens 5.5e-08 35.5 3.1 0.0069 19.4 0.7 4.6 2 sp|Q6ZS30|NBEL1_HUMAN Neurobeachin-like protein 1 OS=Homo 5.6e-08 35.5 1.2 5.3e-05 26.1 0.2 3.2 2 tr|C9J6C8|C9J6C8_HUMAN Actin-related protein 2/3 complex s 5.6e-08 35.5 1.2 5.3e-05 26.1 0.2 3.2 2 tr|C9JFG9|C9JFG9_HUMAN Actin-related protein 2/3 complex s 5.6e-08 35.5 1.2 5.3e-05 26.1 0.2 3.2 2 tr|C9JQM8|C9JQM8_HUMAN Actin-related protein 2/3 complex s 6e-08 35.4 8.0 0.1 15.7 0.3 6.6 3 sp|Q5T5C0|STXB5_HUMAN Syntaxin-binding protein 5 OS=Homo 7.1e-08 35.2 1.0 2.7e-05 27.0 0.5 2.6 2 tr|F8W1H8|F8W1H8_HUMAN Coronin (Fragment) OS=Homo sapiens 7.5e-08 35.1 0.0 0.079 16.1 0.0 3.1 2 tr|H3BPD7|H3BPD7_HUMAN Cirhin (Fragment) OS=Homo sapiens G 7.6e-08 35.1 0.1 4.8e-05 26.2 0.0 3.4 2 sp|Q562E7-4|WDR81_HUMAN Isoform 4 of WD repeat-containing p 8.2e-08 35.0 29.1 0.0083 19.1 0.1 8.6 4 sp|Q15751|HERC1_HUMAN Probable E3 ubiquitin-protein ligas 8.3e-08 35.0 9.1 1.4 12.2 0.0 5.3 4 tr|H0YJY3|H0YJY3_HUMAN Echinoderm microtubule-associated p 8.6e-08 34.9 0.4 3.1e-07 33.2 0.1 2.1 1 tr|I3NI06|I3NI06_HUMAN Coronin (Fragment) OS=Homo sapiens 9e-08 34.9 6.8 0.46 13.6 0.2 4.2 4 tr|G3V4I9|G3V4I9_HUMAN Protein NEDD1 (Fragment) OS=Homo sa 9.1e-08 34.8 13.5 0.012 18.6 1.7 5.6 3 sp|Q9UI46|DNAI1_HUMAN Dynein intermediate chain 1, axonem 1e-07 34.7 0.4 3.6e-07 33.0 0.1 2.1 1 tr|I3L1G9|I3L1G9_HUMAN Coronin OS=Homo sapiens GN=CORO7 PE 1.1e-07 34.6 14.5 0.0065 19.5 0.2 4.8 4 sp|Q12770-3|SCAP_HUMAN Isoform 3 of Sterol regulatory elem 1.1e-07 34.6 0.6 3e-05 26.9 0.5 2.6 2 tr|F8VUX3|F8VUX3_HUMAN Coronin OS=Homo sapiens GN=CORO1C P 1.1e-07 34.6 15.7 0.07 16.2 0.2 5.3 3 tr|B4DLQ7|B4DLQ7_HUMAN Actin-related protein 2/3 complex s 1.2e-07 34.5 1.9 0.02 17.9 0.3 4.9 3 tr|Q3B794|Q3B794_HUMAN STXBP5 protein OS=Homo sapiens GN=S 1.2e-07 34.4 2.7 0.77 12.9 0.2 4.5 3 tr|E5RFG6|E5RFG6_HUMAN TBC1 domain family member 31 (Fragm 1.4e-07 34.3 9.6 0.097 15.8 0.3 6.6 3 sp|Q5T5C0-3|STXB5_HUMAN Isoform 3 of Syntaxin-binding prote 1.6e-07 34.1 9.6 0.098 15.8 0.3 6.6 3 sp|Q5T5C0-2|STXB5_HUMAN Isoform 2 of Syntaxin-binding prote 1.6e-07 34.0 0.1 0.063 16.4 0.1 2.2 2 tr|E7ERC8|E7ERC8_HUMAN Protein SEC13 homolog (Fragment) OS 1.7e-07 34.0 3.0 3.7e-05 26.6 0.2 3.0 2 tr|H7C0S9|H7C0S9_HUMAN WD repeat domain-containing protein 1.8e-07 33.9 2.0 4.9 10.4 0.2 6.1 3 sp|P50851-2|LRBA_HUMAN Isoform 2 of Lipopolysaccharide-res 1.8e-07 33.9 2.0 4.9 10.4 0.2 6.1 3 tr|F5H1X8|F5H1X8_HUMAN Lipopolysaccharide-responsive and b 1.8e-07 33.9 5.3 28 8.0 0.1 6.3 5 sp|Q66LE6|2ABD_HUMAN Serine/threonine-protein phosphatas 1.8e-07 33.9 2.0 4.9 10.4 0.2 6.1 3 sp|P50851|LRBA_HUMAN Lipopolysaccharide-responsive and b 1.8e-07 33.9 0.9 0.0035 20.3 0.1 3.0 2 tr|G3V3S1|G3V3S1_HUMAN DDB1- and CUL4-associated factor 5 2e-07 33.8 3.7 0.0076 19.3 0.1 3.6 2 tr|Q5SVS2|Q5SVS2_HUMAN F-box/WD repeat-containing protein 2.1e-07 33.7 0.6 1.1 12.5 0.0 6.2 3 sp|Q9UG01-2|IF172_HUMAN Isoform 2 of Intraflagellar transpo 2.2e-07 33.7 2.5 19 8.5 0.0 5.6 4 sp|Q96KV7-3|WDR90_HUMAN Isoform 3 of WD repeat-containing p 2.2e-07 33.7 2.5 19 8.5 0.0 5.6 4 sp|Q96KV7-5|WDR90_HUMAN Isoform 5 of WD repeat-containing p 2.4e-07 33.5 0.4 0.00078 22.4 0.0 3.8 2 tr|Q8ND98|Q8ND98_HUMAN Putative uncharacterized protein DK 2.6e-07 33.4 0.0 0.0015 21.5 0.0 2.2 2 tr|D6RHJ5|D6RHJ5_HUMAN Guanine nucleotide-binding protein 2.6e-07 33.4 4.4 0.0045 20.0 0.1 3.9 2 sp|Q6RI45-3|BRWD3_HUMAN Isoform 3 of Bromodomain and WD rep 2.7e-07 33.4 4.9 8.5 9.6 0.1 6.0 4 sp|Q9Y2T4|2ABG_HUMAN Serine/threonine-protein phosphatas 2.7e-07 33.3 2.7 8.5 9.6 0.1 6.0 4 sp|Q9Y2T4-2|2ABG_HUMAN Isoform 2 of Serine/threonine-prote 3.4e-07 33.0 0.2 1.4e-05 27.9 0.0 2.0 2 tr|G3V221|G3V221_HUMAN Mitogen-activated protein kinase or 3.5e-07 33.0 2.8 8.3 9.7 0.1 6.0 4 sp|Q9Y2T4-4|2ABG_HUMAN Isoform 4 of Serine/threonine-prote 3.6e-07 33.0 0.6 2.9 11.1 0.1 4.2 3 tr|C9JQN1|C9JQN1_HUMAN WD repeat-containing protein 53 (Fr 3.6e-07 33.0 7.5 4.4e-05 26.4 0.0 4.0 2 tr|E9PJK2|E9PJK2_HUMAN Polycomb protein EED OS=Homo sapien 3.7e-07 32.9 0.2 5.6e-07 32.3 0.2 1.3 1 tr|H0YNW7|H0YNW7_HUMAN Guanine nucleotide-binding protein 3.8e-07 32.9 0.0 0.39 13.9 0.0 3.1 2 tr|D6RCL6|D6RCL6_HUMAN Coatomer subunit beta' (Fragment) O 3.9e-07 32.8 7.4 0.021 17.9 0.1 5.8 2 sp|Q8NFH3|NUP43_HUMAN Nucleoporin Nup43 OS=Homo sapiens G 4e-07 32.8 7.6 3 11.1 0.1 6.8 3 sp|Q9H808-2|TLE6_HUMAN Isoform 2 of Transducin-like enhanc 4e-07 32.8 14.6 0.72 13.0 0.4 4.4 4 tr|K7EP88|K7EP88_HUMAN Nucleoporin SEH1 (Fragment) OS=Homo 4.2e-07 32.8 0.6 1.3 12.3 0.0 6.2 2 sp|Q9UG01|IF172_HUMAN Intraflagellar transport protein 17 4.3e-07 32.7 9.0 0.089 15.9 0.1 4.8 2 sp|Q9UKT8-2|FBXW2_HUMAN Isoform 2 of F-box/WD repeat-contai 4.4e-07 32.7 0.5 0.023 17.8 0.0 2.5 2 tr|D6RD43|D6RD43_HUMAN Peptidylprolyl isomerase domain and 4.7e-07 32.6 1.2 39 7.5 0.0 6.7 3 tr|F5GZ56|F5GZ56_HUMAN Intraflagellar transport protein 17 4.7e-07 32.6 6.0 0.059 16.5 0.1 4.6 3 tr|K7EKG3|K7EKG3_HUMAN Echinoderm microtubule-associated p 4.7e-07 32.6 0.7 1.9e-05 27.5 0.2 2.1 2 tr|C9JTT6|C9JTT6_HUMAN Actin-related protein 2/3 complex s 5.2e-07 32.4 12.2 0.0058 19.7 0.1 5.7 2 sp|Q6ZS81|WDFY4_HUMAN WD repeat- and FYVE domain-containi 5.3e-07 32.4 0.2 9.1e-07 31.7 0.2 1.4 1 tr|Q96F32|Q96F32_HUMAN GNB5 protein OS=Homo sapiens GN=GNB 5.6e-07 32.4 0.6 3.1e-05 26.8 0.2 2.4 2 tr|H3BNA2|H3BNA2_HUMAN Coronin (Fragment) OS=Homo sapiens 6.1e-07 32.2 8.2 0.042 16.9 0.1 4.0 2 tr|K7EII6|K7EII6_HUMAN Echinoderm microtubule-associated p 6.3e-07 32.2 3.7 8.1 9.7 0.1 6.0 4 sp|Q9Y2T4-3|2ABG_HUMAN Isoform 3 of Serine/threonine-prote 6.3e-07 32.2 1.0 2.4e-06 30.3 0.5 2.2 1 sp|Q5TAQ9-2|DCAF8_HUMAN Isoform 2 of DDB1- and CUL4-associa 6.4e-07 32.2 0.7 9.7e-05 25.3 0.2 2.7 2 tr|F5H0D2|F5H0D2_HUMAN Coronin OS=Homo sapiens GN=CORO1B P 6.6e-07 32.1 11.3 0.12 15.5 0.0 6.1 4 sp|Q99698|LYST_HUMAN Lysosomal-trafficking regulator OS= 6.9e-07 32.1 0.2 0.01 18.9 0.0 2.3 2 tr|H7C4N7|H7C4N7_HUMAN WD repeat domain phosphoinositide-i 7.6e-07 31.9 3.5 0.65 13.2 0.7 3.2 3 tr|H0Y8I2|H0Y8I2_HUMAN Intraflagellar transport protein 12 7.7e-07 31.9 10.6 63 6.9 0.3 7.4 3 sp|Q8N3Y1-2|FBXW8_HUMAN Isoform 2 of F-box/WD repeat-contai 7.8e-07 31.9 5.6 1.2 12.3 0.0 5.3 2 sp|Q9P2H3-2|IFT80_HUMAN Isoform 2 of Intraflagellar transpo 8.2e-07 31.8 6.6 0.054 16.6 0.1 5.1 2 sp|Q6ZQQ6|WDR87_HUMAN WD repeat-containing protein 87 OS= 8.4e-07 31.8 6.6 0.055 16.6 0.1 5.2 2 tr|E7ESW6|E7ESW6_HUMAN WD repeat-containing protein 87 OS= 8.4e-07 31.8 6.6 0.055 16.6 0.1 5.2 2 sp|Q6ZQQ6-2|WDR87_HUMAN Isoform 2 of WD repeat-containing p 8.9e-07 31.7 0.5 0.077 16.1 0.0 3.8 2 sp|A4D1P6-2|WDR91_HUMAN Isoform 2 of WD repeat-containing p 9.3e-07 31.7 10.8 0.0057 19.7 0.1 4.9 2 sp|Q6ZS81-4|WDFY4_HUMAN Isoform 4 of WD repeat- and FYVE do 9.4e-07 31.6 0.1 0.0063 19.5 0.1 2.2 2 tr|H3BTV8|H3BTV8_HUMAN Katanin p80 WD40 repeat-containing 9.9e-07 31.6 0.7 3.1e-05 26.8 0.2 2.2 1 tr|C9JBJ7|C9JBJ7_HUMAN Actin-related protein 2/3 complex s 1.1e-06 31.5 1.0 3.5e-05 26.7 0.2 2.5 1 tr|C9K057|C9K057_HUMAN Actin-related protein 2/3 complex s 1.1e-06 31.4 0.6 0.34 14.1 0.0 4.1 2 sp|P57081-2|WDR4_HUMAN Isoform 2 of tRNA (guanine-N(7)-)-m 1.1e-06 31.4 10.2 0.0064 19.5 0.1 4.2 3 tr|Q5SVS3|Q5SVS3_HUMAN F-box/WD repeat-containing protein 1.2e-06 31.3 0.6 0.34 14.1 0.0 4.1 2 sp|P57081|WDR4_HUMAN tRNA (guanine-N(7)-)-methyltransfer 1.2e-06 31.3 0.2 1.3 12.2 0.0 4.0 3 tr|C9JSB1|C9JSB1_HUMAN Intraflagellar transport protein 80 1.2e-06 31.3 0.1 1.2e-05 28.2 0.0 1.9 1 tr|F5H2L7|F5H2L7_HUMAN WD repeat and SOCS box-containing p 1.2e-06 31.3 6.4 0.00064 22.7 1.0 4.4 3 sp|Q9C0C7-6|AMRA1_HUMAN Isoform 6 of Activating molecule in 1.4e-06 31.1 2.3 0.00042 23.2 0.1 3.7 2 tr|F8VUB6|F8VUB6_HUMAN Aladin (Fragment) OS=Homo sapiens G 1.5e-06 31.0 9.3 0.52 13.5 0.3 6.4 3 tr|F5H050|F5H050_HUMAN Cytoplasmic dynein 1 intermediate c 1.6e-06 30.9 9.3 0.52 13.5 0.3 6.4 3 sp|O14576-3|DC1I1_HUMAN Isoform 3 of Cytoplasmic dynein 1 i 1.8e-06 30.8 5.1 0.69 13.1 0.2 6.7 2 tr|E9PBK6|E9PBK6_HUMAN WD repeat-containing protein 6 OS=H 1.8e-06 30.7 10.5 73 6.7 0.3 7.3 3 sp|Q8N3Y1|FBXW8_HUMAN F-box/WD repeat-containing protein 1.8e-06 30.7 9.8 0.05 16.7 0.5 5.3 2 tr|E7EMZ0|E7EMZ0_HUMAN DmX-like protein 1 (Fragment) OS=Ho 1.9e-06 30.7 9.3 0.54 13.4 0.3 6.3 3 tr|G5E9K1|G5E9K1_HUMAN Cytoplasmic dynein 1 intermediate c 1.9e-06 30.7 9.3 0.54 13.4 0.3 6.3 3 sp|O14576-2|DC1I1_HUMAN Isoform 2 of Cytoplasmic dynein 1 i 1.9e-06 30.6 2.7 0.082 16.0 1.6 4.4 2 sp|Q5VW00|DC122_HUMAN DDB1- and CUL4-associated factor 12 2e-06 30.6 1.5 0.0038 20.2 0.0 3.3 2 sp|Q9H6Y2-2|WDR55_HUMAN Isoform 2 of WD repeat-containing p 2.1e-06 30.5 8.3 0.0014 21.6 0.2 4.5 3 tr|B4DP38|B4DP38_HUMAN Methylosome protein 50 OS=Homo sapi 2.2e-06 30.5 4.7 0.00061 22.7 0.1 4.8 2 tr|H3BU82|H3BU82_HUMAN Aladin (Fragment) OS=Homo sapiens G 2.3e-06 30.4 9.3 0.56 13.4 0.3 6.3 3 sp|O14576|DC1I1_HUMAN Cytoplasmic dynein 1 intermediate c 2.3e-06 30.4 2.7 0.0034 20.4 0.3 3.6 2 sp|Q8NA75|DC4L2_HUMAN DDB1- and CUL4-associated factor 4- 2.3e-06 30.4 7.6 4.1 10.6 0.1 6.7 2 sp|Q9H808|TLE6_HUMAN Transducin-like enhancer protein 6 2.3e-06 30.4 0.9 2.7 11.2 0.1 4.2 2 tr|C9JDR5|C9JDR5_HUMAN WD repeat-containing protein 53 (Fr 2.9e-06 30.1 8.3 0.00076 22.4 0.1 5.2 3 tr|F8VZ44|F8VZ44_HUMAN Aladin OS=Homo sapiens GN=AAAS PE=2 3e-06 30.0 1.5 0.00035 23.5 0.2 2.2 2 tr|H0Y9P0|H0Y9P0_HUMAN Guanine nucleotide-binding protein 3.8e-06 29.7 2.6 0.044 16.9 0.1 4.2 3 tr|H0Y4Q6|H0Y4Q6_HUMAN General transcription factor 3C pol 4.7e-06 29.4 0.9 1.5e-05 27.9 0.4 2.2 1 sp|Q969U6-2|FBXW5_HUMAN Isoform 2 of F-box/WD repeat-contai 5.3e-06 29.3 1.0 6.3e-06 29.0 0.5 1.4 1 tr|U3KQK3|U3KQK3_HUMAN WD repeat-containing protein 18 (Fr 7.1e-06 28.9 11.5 0.68 13.1 0.6 6.9 4 sp|Q13409-6|DC1I2_HUMAN Isoform 2F of Cytoplasmic dynein 1 7.2e-06 28.8 11.5 0.68 13.1 0.6 6.9 4 sp|Q13409-3|DC1I2_HUMAN Isoform 2C of Cytoplasmic dynein 1 8.5e-06 28.6 11.5 0.71 13.0 0.6 6.9 4 tr|B7ZA04|B7ZA04_HUMAN Cytoplasmic dynein 1 intermediate c 8.8e-06 28.6 11.5 0.71 13.0 0.6 6.9 4 sp|Q13409-2|DC1I2_HUMAN Isoform 2B of Cytoplasmic dynein 1 9.3e-06 28.5 11.5 0.72 13.0 0.6 6.9 4 sp|Q13409-5|DC1I2_HUMAN Isoform 2E of Cytoplasmic dynein 1 9.3e-06 28.5 11.5 0.72 13.0 0.6 6.9 4 tr|F8W8S0|F8W8S0_HUMAN Cytoplasmic dynein 1 intermediate c 9.4e-06 28.5 11.5 0.72 13.0 0.6 6.9 4 sp|Q13409|DC1I2_HUMAN Cytoplasmic dynein 1 intermediate c 9.8e-06 28.4 0.1 2.2e-05 27.3 0.0 1.6 1 tr|B1AKQ8|B1AKQ8_HUMAN Guanine nucleotide-binding protein 1.2e-05 28.2 0.0 0.0031 20.5 0.0 2.2 2 tr|K7ERC0|K7ERC0_HUMAN WD repeat-containing protein 16 (Fr 1.2e-05 28.1 1.6 0.2 14.8 0.2 2.2 2 tr|J3KTF7|J3KTF7_HUMAN CMT1A duplicated region transcript 1.3e-05 28.0 6.0 0.024 17.7 0.4 3.9 3 tr|K7EKU5|K7EKU5_HUMAN Echinoderm microtubule-associated p 1.5e-05 27.9 0.7 1.5e-05 27.9 0.7 1.9 1 tr|K7EPH1|K7EPH1_HUMAN WD repeat-containing protein 88 OS= 1.5e-05 27.8 11.0 0.00053 22.9 2.0 3.2 2 tr|H0YJK4|H0YJK4_HUMAN Echinoderm microtubule-associated p 1.8e-05 27.6 1.6 0.24 14.5 0.2 2.3 2 tr|J3QLS4|J3QLS4_HUMAN CMT1A duplicated region transcript 1.8e-05 27.6 5.0 0.00053 22.9 0.2 3.1 2 tr|B0QZ36|B0QZ36_HUMAN mRNA export factor (Fragment) OS=Ho 1.8e-05 27.6 1.4 0.56 13.4 0.0 5.0 2 sp|Q15334|L2GL1_HUMAN Lethal(2) giant larvae protein homo 1.9e-05 27.5 5.0 0.37 13.9 0.1 4.9 3 sp|Q9BTV6|DPH7_HUMAN Diphthamide biosynthesis protein 7 2e-05 27.4 0.1 0.49 13.6 0.2 4.0 2 tr|J3KSR7|J3KSR7_HUMAN U3 small nucleolar RNA-associated p 2e-05 27.4 9.2 0.17 15.0 1.0 4.6 3 sp|P61962|DCAF7_HUMAN DDB1- and CUL4-associated factor 7 2.1e-05 27.3 5.3 4.5 10.5 0.2 6.0 3 sp|Q96DN5-3|TBC31_HUMAN Isoform 3 of TBC1 domain family mem 2.3e-05 27.2 6.2 7.3 9.8 0.2 6.6 3 sp|Q9BZH6|WDR11_HUMAN WD repeat-containing protein 11 OS= 2.4e-05 27.2 9.6 0.0011 22.0 0.1 5.3 2 sp|Q9NRG9|AAAS_HUMAN Aladin OS=Homo sapiens GN=AAAS PE=1 2.4e-05 27.2 11.1 5.7 10.2 0.3 7.0 3 tr|Q5T321|Q5T321_HUMAN Neurobeachin OS=Homo sapiens GN=NBE 2.5e-05 27.1 4.0 0.0011 22.0 0.4 3.5 2 tr|F5H8E6|F5H8E6_HUMAN WD repeat-containing protein 20 OS= 2.5e-05 27.1 2.2 0.029 17.4 0.1 3.9 2 tr|B3KRG7|B3KRG7_HUMAN DENN domain-containing protein 3 OS 2.6e-05 27.1 0.1 0.3 14.2 0.0 2.3 2 tr|D6RAF7|D6RAF7_HUMAN Intraflagellar transport protein 12 2.6e-05 27.1 5.5 0.00098 22.1 0.1 4.4 2 sp|Q9NRG9-2|AAAS_HUMAN Isoform 2 of Aladin OS=Homo sapiens 2.6e-05 27.1 1.6 0.2 14.8 0.0 4.7 2 tr|J3QRV5|J3QRV5_HUMAN Lethal(2) giant larvae protein homo 2.6e-05 27.1 1.6 0.2 14.8 0.0 4.7 2 sp|Q6P1M3|L2GL2_HUMAN Lethal(2) giant larvae protein homo 2.6e-05 27.1 5.3 4.6 10.5 0.2 6.0 3 sp|Q96DN5-2|TBC31_HUMAN Isoform 2 of TBC1 domain family mem 2.7e-05 27.0 1.6 0.2 14.8 0.0 4.6 2 sp|Q6P1M3-2|L2GL2_HUMAN Isoform A of Lethal(2) giant larvae 2.7e-05 27.0 0.0 0.023 17.8 0.0 2.1 2 tr|J3KSE6|J3KSE6_HUMAN Cirhin (Fragment) OS=Homo sapiens G 2.7e-05 27.0 11.2 5.7 10.2 0.3 7.0 3 sp|Q8NFP9|NBEA_HUMAN Neurobeachin OS=Homo sapiens GN=NBE 2.7e-05 27.0 11.2 5.7 10.2 0.3 7.0 3 tr|F5GXV7|F5GXV7_HUMAN Neurobeachin OS=Homo sapiens GN=NBE 3.4e-05 26.7 1.6 0.00024 24.0 0.2 2.3 1 tr|H0YGB1|H0YGB1_HUMAN Proteasomal ATPase-associated facto 3.5e-05 26.7 0.1 9.4e-05 25.3 0.0 1.7 1 tr|C9IZ29|C9IZ29_HUMAN WD repeat-containing protein 49 (Fr 3.5e-05 26.7 4.1 0.81 12.9 0.0 5.2 3 sp|Q5VTH9-3|WDR78_HUMAN Isoform 3 of WD repeat-containing p 3.7e-05 26.6 1.6 19 8.6 0.0 5.1 3 tr|H0Y6L4|H0Y6L4_HUMAN WD repeat-containing protein 64 (Fr 3.7e-05 26.6 11.7 0.15 15.2 0.3 5.4 2 sp|Q8IZQ1-2|WDFY3_HUMAN Isoform 2 of WD repeat and FYVE dom 3.7e-05 26.6 8.3 1.9 11.7 0.0 5.4 2 tr|H3BRJ5|H3BRJ5_HUMAN Uncharacterized protein OS=Homo sap 3.8e-05 26.5 11.7 0.15 15.2 0.3 5.4 2 sp|Q8IZQ1|WDFY3_HUMAN WD repeat and FYVE domain-containin 3.9e-05 26.5 0.1 3.6 10.8 0.0 3.3 3 tr|J3QRG0|J3QRG0_HUMAN U3 small nucleolar RNA-associated p 4.2e-05 26.4 2.4 14 9.0 0.0 5.7 2 tr|F8WB94|F8WB94_HUMAN WD repeat-containing protein 35 OS= 4.2e-05 26.4 1.6 1.1 12.4 0.0 5.9 1 tr|D6RCR1|D6RCR1_HUMAN Uncharacterized protein OS=Homo sap 4.2e-05 26.4 0.2 7.3e-05 25.7 0.1 1.5 1 tr|H0Y9T1|H0Y9T1_HUMAN THO complex subunit 3 (Fragment) OS 4.3e-05 26.4 4.1 0.84 12.8 0.0 5.2 3 tr|H0YDI6|H0YDI6_HUMAN WD repeat-containing protein 78 (Fr 4.3e-05 26.4 2.8 2.8 11.2 0.2 5.2 2 tr|E7ESI5|E7ESI5_HUMAN TBC1 domain family member 31 OS=Hom 4.4e-05 26.4 1.9 0.019 18.0 0.4 3.2 2 tr|G3V2M9|G3V2M9_HUMAN Protein NEDD1 (Fragment) OS=Homo sa 4.6e-05 26.3 1.3 0.082 16.0 1.6 4.0 2 sp|Q5VU92|DC121_HUMAN DDB1- and CUL4-associated factor 12 4.7e-05 26.3 3.4 0.0012 21.8 1.7 2.5 2 tr|H0Y6V0|H0Y6V0_HUMAN Dynein intermediate chain 1, axonem 5.5e-05 26.1 0.3 0.18 14.9 0.0 3.0 2 sp|P57081-3|WDR4_HUMAN Isoform 3 of tRNA (guanine-N(7)-)-m 5.5e-05 26.0 0.3 0.00022 24.1 0.0 2.1 1 tr|D6RJA5|D6RJA5_HUMAN WD repeat-containing protein 41 (Fr 5.6e-05 26.0 5.8 5 10.4 0.2 6.0 3 sp|Q96DN5|TBC31_HUMAN TBC1 domain family member 31 OS=Hom 6.2e-05 25.9 2.4 0.33 14.1 0.5 3.4 2 sp|Q13216-2|ERCC8_HUMAN Isoform 2 of DNA excision repair pr 6.3e-05 25.9 1.0 0.41 13.8 0.3 3.3 2 tr|J3QR85|J3QR85_HUMAN U3 small nucleolar RNA-associated p 6.3e-05 25.9 6.1 10 9.3 0.0 6.2 3 sp|Q8NEZ3-2|WDR19_HUMAN Isoform 2 of WD repeat-containing p 6.3e-05 25.9 6.1 10 9.3 0.0 6.2 3 tr|D6R9P6|D6R9P6_HUMAN WD repeat domain 19, isoform CRA_a 6.5e-05 25.8 0.0 0.3 14.2 0.0 3.1 2 tr|D6RBZ7|D6RBZ7_HUMAN Coatomer subunit beta' (Fragment) O 6.5e-05 25.8 10.3 0.0011 21.9 1.0 4.8 2 sp|Q9C0C7-4|AMRA1_HUMAN Isoform 4 of Activating molecule in 7e-05 25.7 0.4 1.1 12.5 0.0 3.5 2 sp|Q8WV16-4|DCAF4_HUMAN Isoform 4 of DDB1- and CUL4-associa 7e-05 25.7 10.3 0.0011 21.9 1.0 4.8 2 sp|Q9C0C7-2|AMRA1_HUMAN Isoform 2 of Activating molecule in 7.4e-05 25.6 0.0 0.82 12.8 0.0 2.9 2 tr|Q86SY2|Q86SY2_HUMAN DDB1- and CUL4-associated factor 4 7.4e-05 25.6 0.0 21 8.4 0.0 4.2 3 sp|Q9Y4P8-2|WIPI2_HUMAN Isoform 2 of WD repeat domain phosp 7.7e-05 25.6 10.3 0.0012 21.9 1.0 4.8 2 sp|Q9C0C7-3|AMRA1_HUMAN Isoform 3 of Activating molecule in 7.8e-05 25.6 10.1 0.0012 21.8 1.0 4.8 2 sp|Q9C0C7-5|AMRA1_HUMAN Isoform 5 of Activating molecule in 8.3e-05 25.5 0.0 21 8.4 0.0 4.2 3 sp|Q9Y4P8-4|WIPI2_HUMAN Isoform 4 of WD repeat domain phosp 8.3e-05 25.5 0.4 2.2 11.5 0.1 2.9 2 sp|Q8TAF3-5|WDR48_HUMAN Isoform 5 of WD repeat-containing p 8.3e-05 25.5 0.0 18 8.6 0.0 3.8 3 sp|Q9Y4P8-3|WIPI2_HUMAN Isoform 3 of WD repeat domain phosp 8.6e-05 25.4 0.4 1.2 12.3 0.0 3.6 2 sp|Q8WV16-3|DCAF4_HUMAN Isoform 3 of DDB1- and CUL4-associa 8.6e-05 25.4 10.3 0.0012 21.8 1.0 4.7 2 sp|Q9C0C7|AMRA1_HUMAN Activating molecule in BECN1-regula 8.6e-05 25.4 1.2 19 8.5 0.0 5.4 2 sp|Q9P2L0-2|WDR35_HUMAN Isoform 2 of WD repeat-containing p 8.7e-05 25.4 0.0 0.035 17.2 0.0 3.8 1 tr|H0Y6G3|H0Y6G3_HUMAN WD repeat-containing protein 46 (Fr 9e-05 25.4 1.2 19 8.5 0.0 5.4 2 sp|Q9P2L0|WDR35_HUMAN WD repeat-containing protein 35 OS= 9.1e-05 25.4 2.0 2.7e+02 4.9 0.0 6.4 3 sp|O94979-5|SC31A_HUMAN Isoform 5 of Protein transport prot 9.9e-05 25.2 0.5 0.094 15.8 0.1 3.3 2 tr|H0YF49|H0YF49_HUMAN E3 ubiquitin-protein ligase RFWD2 ( 0.0001 25.2 0.0 0.00012 25.0 0.0 1.1 1 tr|J3KSQ3|J3KSQ3_HUMAN WD repeat and SOCS box-containing p 0.0001 25.2 0.7 0.012 18.6 0.1 3.4 1 sp|Q6P2E9|EDC4_HUMAN Enhancer of mRNA-decapping protein 0.00011 25.2 0.1 0.42 13.8 0.0 2.6 2 tr|H7C4Y4|H7C4Y4_HUMAN WD repeat-containing protein 49 (Fr 0.00011 25.1 0.1 0.2 14.8 0.0 2.3 2 tr|H0YAG9|H0YAG9_HUMAN Intraflagellar transport protein 12 0.00013 24.9 0.0 22 8.3 0.0 3.9 3 sp|Q9Y4P8-6|WIPI2_HUMAN Isoform 6 of WD repeat domain phosp 0.00013 24.9 0.0 21 8.4 0.0 3.9 3 sp|Q9Y4P8-5|WIPI2_HUMAN Isoform 5 of WD repeat domain phosp 0.00013 24.9 0.3 1.4 12.1 0.0 3.5 2 sp|Q8WV16|DCAF4_HUMAN DDB1- and CUL4-associated factor 4 0.00014 24.8 10.7 0.00037 23.4 0.1 4.1 1 tr|H0YAE4|H0YAE4_HUMAN WD repeat-containing protein 17 (Fr 0.00014 24.8 2.7 0.12 15.5 0.2 2.6 2 tr|G3V2S2|G3V2S2_HUMAN Protein NEDD1 OS=Homo sapiens GN=NE 0.00014 24.7 0.6 0.042 16.9 0.0 3.6 1 tr|H0Y329|H0Y329_HUMAN WD repeat domain phosphoinositide-i 0.00014 24.7 0.0 22 8.3 0.0 3.9 3 sp|Q9Y4P8|WIPI2_HUMAN WD repeat domain phosphoinositide-i 0.00014 24.7 0.3 1.4 12.1 0.0 3.4 2 sp|Q8WV16-5|DCAF4_HUMAN Isoform 5 of DDB1- and CUL4-associa 0.00019 24.4 0.1 0.00031 23.7 0.1 1.4 1 tr|Q5JNZ6|Q5JNZ6_HUMAN Histone-binding protein RBBP7 (Frag 0.0002 24.2 1.1 0.22 14.6 0.1 4.1 2 sp|A2RUS2-2|DEND3_HUMAN Isoform 2 of DENN domain-containing 0.00021 24.2 0.5 0.046 16.8 0.3 3.0 2 tr|D6RFM8|D6RFM8_HUMAN WD repeat-containing protein 36 (Fr 0.00023 24.1 0.5 0.93 12.7 0.0 3.7 2 tr|H3BRM8|H3BRM8_HUMAN Cirhin (Fragment) OS=Homo sapiens G 0.00023 24.1 1.1 0.23 14.6 0.1 4.1 1 sp|A2RUS2|DEND3_HUMAN DENN domain-containing protein 3 OS 0.00024 24.0 9.4 0.0022 21.0 1.3 3.4 2 tr|G3V3N9|G3V3N9_HUMAN Echinoderm microtubule-associated p 0.00025 24.0 1.1 0.23 14.6 0.1 4.1 1 tr|H0YAY3|H0YAY3_HUMAN DENN domain-containing protein 3 (F 0.00025 24.0 3.2 45 7.3 0.0 5.7 2 tr|Q5T0D5|Q5T0D5_HUMAN WD repeat-containing protein WRAP73 0.00028 23.8 0.1 0.71 13.0 0.0 2.3 2 tr|I3L2E7|I3L2E7_HUMAN Target of rapamycin complex subunit 0.00029 23.8 8.7 0.23 14.6 3.5 2.5 2 tr|K7EPZ5|K7EPZ5_HUMAN Nucleoporin SEH1 (Fragment) OS=Homo 0.00029 23.8 1.1 0.25 14.5 0.1 4.1 1 tr|E9PF32|E9PF32_HUMAN DENN domain-containing protein 3 OS 0.0003 23.7 0.1 0.044 16.9 0.2 2.2 2 tr|C9JBU3|C9JBU3_HUMAN WD repeat-containing protein 82 (Fr 0.00031 23.7 0.0 0.38 13.9 0.0 2.4 2 tr|H0Y9E5|H0Y9E5_HUMAN Intraflagellar transport protein 12 0.00033 23.6 2.8 4.3 10.6 0.2 5.0 2 tr|E7EWW7|E7EWW7_HUMAN TBC1 domain family member 31 OS=Hom 0.00036 23.5 2.8 4.4 10.5 0.2 5.0 2 tr|E7ERK7|E7ERK7_HUMAN TBC1 domain family member 31 OS=Hom 0.00037 23.4 1.5 0.0017 21.3 1.5 2.1 1 tr|G3V500|G3V500_HUMAN Echinoderm microtubule-associated p 0.00038 23.4 11.4 2.8 11.2 0.0 6.1 3 tr|Q4G115|Q4G115_HUMAN DNAI2 protein OS=Homo sapiens GN=DN 0.0004 23.3 0.5 3.2 11.0 0.1 2.2 2 tr|H0YAA2|H0YAA2_HUMAN Pleiotropic regulator 1 (Fragment) 0.0004 23.3 0.5 0.00087 22.2 0.5 1.6 1 tr|D6RGZ2|D6RGZ2_HUMAN THO complex subunit 3 OS=Homo sapie 0.00048 23.1 0.7 4.7 10.4 0.1 3.5 2 tr|E5RFR9|E5RFR9_HUMAN Serine/threonine-protein phosphatas 0.00048 23.1 0.1 0.73 13.0 0.0 2.3 2 tr|H3BR38|H3BR38_HUMAN Target of rapamycin complex subunit 0.00053 22.9 3.5 0.081 16.0 0.0 5.1 1 sp|O15213|WDR46_HUMAN WD repeat-containing protein 46 OS= 0.00056 22.9 0.0 0.00077 22.4 0.0 1.2 1 tr|D6RGK8|D6RGK8_HUMAN Guanine nucleotide-binding protein 0.00056 22.9 0.0 7 9.9 0.0 3.3 2 sp|Q92466-2|DDB2_HUMAN Isoform D1 of DNA damage-binding pr 0.00072 22.5 0.6 1.9 11.7 0.0 3.1 2 tr|F8VTY2|F8VTY2_HUMAN Nucleoporin Nup37 (Fragment) OS=Hom 0.00076 22.4 0.6 0.1 15.7 0.0 3.2 1 tr|H7C3C8|H7C3C8_HUMAN Neurobeachin-like protein 1 (Fragme 0.00077 22.4 0.4 1.9 11.7 0.0 4.0 2 tr|E9PDB0|E9PDB0_HUMAN Uncharacterized protein OS=Homo sap 0.00079 22.4 0.1 0.0067 19.5 0.0 2.6 1 tr|C9K020|C9K020_HUMAN WD repeat-containing protein 6 (Fra 0.00091 22.2 0.4 0.002 21.1 0.4 1.6 1 tr|H7C355|H7C355_HUMAN Echinoderm microtubule-associated p 0.00095 22.1 0.1 0.0014 21.6 0.1 1.3 1 tr|K7ERF4|K7ERF4_HUMAN Coronin (Fragment) OS=Homo sapiens 0.00099 22.1 9.5 0.15 15.1 0.5 4.1 3 tr|C9JNT2|C9JNT2_HUMAN DNA excision repair protein ERCC-8 0.0012 21.8 0.1 15 8.9 0.0 3.6 2 sp|Q3SXM0|DC4L1_HUMAN DDB1- and CUL4-associated factor 4- 0.0013 21.7 2.3 35 7.7 0.0 5.9 1 sp|Q8NEZ3|WDR19_HUMAN WD repeat-containing protein 19 OS= 0.0013 21.7 3.2 0.0042 20.1 0.8 3.2 1 tr|B9TWZ6|B9TWZ6_HUMAN Mediator complex subunit MED16 vari 0.0014 21.6 11.5 0.43 13.7 0.0 5.9 2 tr|B4DGE3|B4DGE3_HUMAN Protein transport protein Sec31B OS 0.0015 21.5 2.7 5.7 10.2 1.0 4.4 2 sp|Q5T6F0|DCA12_HUMAN DDB1- and CUL4-associated factor 12 0.0015 21.5 0.4 0.27 14.4 0.1 2.9 2 sp|Q9C0J8-2|WDR33_HUMAN Isoform 2 of pre-mRNA 3' end proces 0.0016 21.4 0.0 2.6 11.3 0.0 2.2 2 tr|H0YAG6|H0YAG6_HUMAN Intraflagellar transport protein 12 0.0017 21.4 1.1 0.0017 21.4 1.1 2.0 1 tr|F2Z2B5|F2Z2B5_HUMAN Echinoderm microtubule-associated p 0.0017 21.3 0.7 15 8.9 0.0 4.5 2 tr|G8JLI5|G8JLI5_HUMAN WD repeat domain phosphoinositide-i 0.0018 21.3 11.7 0.43 13.7 0.0 5.8 2 sp|Q9NQW1-2|SC31B_HUMAN Isoform 2 of Protein transport prot 0.0018 21.2 2.8 0.0055 19.7 0.8 3.0 1 tr|U3KQ43|U3KQ43_HUMAN Mediator of RNA polymerase II trans 0.0018 21.2 2.8 0.0055 19.7 0.8 3.0 1 sp|Q9Y2X0-5|MED16_HUMAN Isoform 5 of Mediator of RNA polyme 0.0019 21.2 1.3 3.3 10.9 0.1 4.2 2 tr|H7C3C0|H7C3C0_HUMAN Intraflagellar transport 122 homolo 0.0019 21.2 11.7 0.43 13.7 0.0 5.8 2 tr|E9PKR7|E9PKR7_HUMAN Protein transport protein Sec31B OS 0.0021 21.1 0.5 0.0096 18.9 0.5 2.0 1 tr|K7EQR0|K7EQR0_HUMAN Echinoderm microtubule-associated p 0.0021 21.0 0.3 1.1e+02 6.2 0.0 4.4 2 tr|H0Y9T9|H0Y9T9_HUMAN Protein transport protein Sec31A (F 0.0021 21.0 1.9 0.23 14.6 0.0 2.7 2 tr|H0YDT9|H0YDT9_HUMAN Dynein intermediate chain 1, axonem 0.0023 20.9 1.7 5.3e+02 4.0 0.0 6.3 2 tr|D6RHZ5|D6RHZ5_HUMAN Protein transport protein Sec31A OS 0.0023 20.9 1.9 0.94 12.6 0.1 3.3 2 sp|Q9H6U6-6|BCAS3_HUMAN Isoform 6 of Breast carcinoma-ampli 0.0025 20.8 1.9 0.97 12.6 0.1 3.3 2 tr|K7ESE9|K7ESE9_HUMAN Breast carcinoma-amplified sequence 0.0026 20.8 17.4 3.5 10.8 4.1 6.2 2 sp|Q8IWG1-2|WDR63_HUMAN Isoform 2 of WD repeat-containing p 0.0029 20.6 2.9 0.0073 19.3 0.8 2.9 1 sp|Q9Y2X0-2|MED16_HUMAN Isoform 2 of Mediator of RNA polyme 0.003 20.6 1.7 2.1 11.6 0.1 3.9 2 sp|Q8WVS4|WDR60_HUMAN WD repeat-containing protein 60 OS= 0.003 20.5 0.1 46 7.3 0.0 3.9 2 tr|F5H6G7|F5H6G7_HUMAN Nucleolar protein 10 OS=Homo sapien 0.003 20.5 0.0 42 7.4 0.0 3.9 2 sp|Q9BSC4|NOL10_HUMAN Nucleolar protein 10 OS=Homo sapien 0.0031 20.5 2.9 0.0075 19.3 0.8 2.9 1 sp|Q9Y2X0-3|MED16_HUMAN Isoform 3 of Mediator of RNA polyme 0.0032 20.5 0.0 0.0051 19.8 0.0 1.3 1 tr|K7EJ50|K7EJ50_HUMAN Telomerase Cajal body protein 1 (Fr 0.0033 20.4 2.9 0.0077 19.3 0.8 2.9 1 sp|Q9Y2X0|MED16_HUMAN Mediator of RNA polymerase II trans 0.0034 20.4 0.4 0.018 18.1 0.2 1.9 1 tr|C9J355|C9J355_HUMAN WD repeat-containing protein 82 (Fr 0.0035 20.3 0.8 0.0035 20.3 0.8 2.7 1 tr|K7EKS6|K7EKS6_HUMAN Mediator of RNA polymerase II trans 0.0037 20.2 17.5 4.1 10.6 4.2 6.2 2 sp|Q8IWG1|WDR63_HUMAN WD repeat-containing protein 63 OS= 0.0038 20.2 1.7 0.012 18.7 0.5 2.4 1 tr|K7ERY9|K7ERY9_HUMAN Echinoderm microtubule-associated p 0.0039 20.2 0.0 0.056 16.5 0.0 2.7 1 tr|B4DWR9|B4DWR9_HUMAN Peptidylprolyl isomerase domain and 0.0039 20.2 2.6 0.015 18.3 0.0 2.9 1 tr|E5RHM4|E5RHM4_HUMAN DDB1- and CUL4-associated factor 13 0.004 20.1 2.2 0.019 18.0 0.2 2.5 1 tr|K7ELI8|K7ELI8_HUMAN Echinoderm microtubule-associated p 0.0041 20.1 0.5 0.25 14.5 0.0 4.3 1 sp|O15040|TCPR2_HUMAN Tectonin beta-propeller repeat-cont 0.0042 20.1 10.9 4.7 10.4 0.0 6.1 2 sp|Q9GZS0|DNAI2_HUMAN Dynein intermediate chain 2, axonem 0.0042 20.1 0.0 0.0086 19.1 0.0 1.5 1 tr|H0Y8N5|H0Y8N5_HUMAN Peptidylprolyl isomerase domain and 0.0042 20.1 1.8 0.033 17.3 0.1 3.2 1 sp|A2RUS2-3|DEND3_HUMAN Isoform 3 of DENN domain-containing 0.0045 20.0 1.1 9.6 9.5 0.0 3.7 2 tr|C9J471|C9J471_HUMAN WD repeat domain phosphoinositide-i 0.005 19.8 1.6 0.013 18.5 0.1 2.4 1 tr|H7C3X9|H7C3X9_HUMAN General transcription factor 3C pol 0.0054 19.8 10.5 5.2 10.3 0.0 6.1 2 tr|J3QRG2|J3QRG2_HUMAN Dynein intermediate chain 2, axonem 0.0063 19.5 2.3 1.3 12.2 0.1 3.2 2 sp|Q9H6U6-2|BCAS3_HUMAN Isoform 1 of Breast carcinoma-ampli 0.0064 19.5 2.3 1.4 12.1 0.1 3.3 2 sp|Q9H6U6-3|BCAS3_HUMAN Isoform 3 of Breast carcinoma-ampli 0.0064 19.5 0.8 0.0064 19.5 0.8 3.5 1 sp|Q9Y2X0-4|MED16_HUMAN Isoform 4 of Mediator of RNA polyme 0.0065 19.5 2.3 1.4 12.1 0.1 3.2 2 sp|Q9H6U6-7|BCAS3_HUMAN Isoform 5 of Breast carcinoma-ampli 0.0065 19.5 0.7 0.85 12.8 0.0 3.6 1 tr|G3V3D6|G3V3D6_HUMAN DDB1- and CUL4-associated factor 4 0.0065 19.5 2.3 1.4 12.1 0.1 3.2 2 sp|Q9H6U6|BCAS3_HUMAN Breast carcinoma-amplified sequence 0.0066 19.5 2.3 1.4 12.1 0.1 3.2 2 sp|Q9H6U6-8|BCAS3_HUMAN Isoform 4 of Breast carcinoma-ampli 0.0069 19.4 0.3 0.018 18.1 0.3 1.8 1 tr|Q5TAQ8|Q5TAQ8_HUMAN DDB1- and CUL4-associated factor 8 0.0078 19.2 1.1 0.042 16.9 1.0 2.2 1 tr|B4E039|B4E039_HUMAN DDB1- and CUL4-associated factor 7 0.0089 19.1 1.9 22 8.3 0.0 4.0 2 tr|Q5TBW1|Q5TBW1_HUMAN WD repeat-containing protein WRAP73 0.009 19.0 11.1 0.66 13.1 0.0 5.6 2 sp|Q9NQW1-4|SC31B_HUMAN Isoform 4 of Protein transport prot 0.0092 19.0 5.1 2 11.6 0.0 4.9 2 sp|Q9NQW1-5|SC31B_HUMAN Isoform 5 of Protein transport prot 0.0097 18.9 5.1 2 11.6 0.0 4.9 2 sp|Q9NQW1|SC31B_HUMAN Protein transport protein Sec31B OS 0.0099 18.9 2.2 0.22 14.6 0.0 4.4 1 sp|O15040-2|TCPR2_HUMAN Isoform 2 of Tectonin beta-propelle ------ inclusion threshold ------ 0.01 18.9 0.1 0.013 18.5 0.1 1.2 1 tr|H0YM76|H0YM76_HUMAN WD repeat-containing protein 61 OS= 0.011 18.8 0.0 0.015 18.3 0.0 1.3 1 tr|H0YFZ7|H0YFZ7_HUMAN Autophagy-related protein 16-2 (Fra 0.012 18.7 0.0 3.7 10.8 0.0 2.1 2 tr|H7C5M3|H7C5M3_HUMAN Intraflagellar transport protein 80 0.012 18.7 5.0 0.11 15.6 0.1 4.4 1 sp|Q9UFC0|LRWD1_HUMAN Leucine-rich repeat and WD repeat-c 0.012 18.6 0.0 0.018 18.1 0.0 1.3 1 tr|C9JD14|C9JD14_HUMAN Guanine nucleotide-binding protein 0.014 18.4 0.2 0.46 13.6 0.1 2.2 1 tr|F8WE20|F8WE20_HUMAN WD repeat-containing protein 75 OS= 0.016 18.2 0.9 1.2 12.3 0.0 3.5 1 sp|Q8WV16-2|DCAF4_HUMAN Isoform 2 of DDB1- and CUL4-associa 0.017 18.2 0.3 3.1 11.0 0.1 4.0 1 tr|E9PDG2|E9PDG2_HUMAN Intraflagellar transport protein 12 0.017 18.2 0.8 18 8.6 0.0 4.0 1 tr|B9A049|B9A049_HUMAN WD repeat-containing protein 54 OS= 0.021 17.9 0.0 7.3 9.8 0.0 2.1 2 tr|C9JUJ1|C9JUJ1_HUMAN Intraflagellar transport protein 80 0.022 17.8 0.2 0.59 13.3 0.1 2.2 1 tr|F8WC81|F8WC81_HUMAN WD repeat-containing protein 75 OS= 0.022 17.8 0.4 7.3 9.8 0.0 3.4 1 sp|Q92466-5|DDB2_HUMAN Isoform D4 of DNA damage-binding pr 0.025 17.7 0.6 14 8.9 0.1 3.3 2 tr|H0YA17|H0YA17_HUMAN Lipopolysaccharide-responsive and b 0.028 17.5 0.7 0.033 17.2 0.0 1.6 1 tr|H7C5P3|H7C5P3_HUMAN Intraflagellar transport protein 80 0.029 17.4 0.6 2.1 11.6 0.0 2.9 1 tr|H3BNC5|H3BNC5_HUMAN Intraflagellar transport protein 14 0.03 17.4 0.2 0.12 15.5 0.2 1.8 1 tr|E5RG45|E5RG45_HUMAN TBC1 domain family member 31 (Fragm 0.031 17.4 0.1 15 8.8 0.0 3.4 2 sp|Q9BSC4-3|NOL10_HUMAN Isoform 3 of Nucleolar protein 10 O 0.032 17.3 0.1 32 7.8 0.0 3.4 2 tr|C9J5L0|C9J5L0_HUMAN WD repeat domain phosphoinositide-i 0.033 17.3 0.5 0.36 14.0 0.0 2.2 1 tr|H3BQ74|H3BQ74_HUMAN Target of rapamycin complex subunit 0.034 17.2 7.0 28 8.0 0.0 5.0 2 sp|Q9H967|WDR76_HUMAN WD repeat-containing protein 76 OS= 0.034 17.2 0.5 0.034 17.2 0.5 2.4 1 tr|K7ER35|K7ER35_HUMAN Elongator complex protein 2 OS=Homo 0.035 17.2 0.0 3.2 11.0 0.0 2.3 2 tr|J3QLD6|J3QLD6_HUMAN U3 small nucleolar RNA-associated p 0.037 17.1 0.4 1.2e+02 6.0 0.0 4.3 2 sp|Q5MNZ9-2|WIPI1_HUMAN Isoform 2 of WD repeat domain phosp 0.038 17.1 11.3 4.6 10.5 0.0 5.5 2 sp|Q9GZS0-2|DNAI2_HUMAN Isoform 2 of Dynein intermediate ch 0.038 17.1 0.4 1.3e+02 5.9 0.0 4.3 2 sp|Q5MNZ9|WIPI1_HUMAN WD repeat domain phosphoinositide-i 0.039 17.0 0.3 34 7.7 0.0 2.3 2 tr|D6RCF7|D6RCF7_HUMAN WD repeat-containing protein 19 OS= 0.04 17.0 0.0 0.073 16.2 0.0 1.4 1 tr|K7EIM1|K7EIM1_HUMAN Echinoderm microtubule-associated p 0.04 17.0 0.3 35 7.7 0.0 2.3 2 tr|D6RBA0|D6RBA0_HUMAN WD repeat-containing protein 19 OS= 0.046 16.8 0.7 0.15 15.2 0.3 2.2 1 tr|K7EJH7|K7EJH7_HUMAN Breast carcinoma-amplified sequence 0.049 16.7 0.5 0.049 16.7 0.5 2.4 1 tr|F5GYE9|F5GYE9_HUMAN Elongator complex protein 2 OS=Homo 0.049 16.7 0.3 93 6.3 0.0 3.8 2 tr|K7EK57|K7EK57_HUMAN WD repeat domain phosphoinositide-i 0.054 16.6 0.9 0.15 15.2 0.1 2.2 1 tr|K7EML5|K7EML5_HUMAN Breast carcinoma-amplified sequence 0.059 16.5 0.0 15 8.8 0.0 2.8 2 tr|H0YCY3|H0YCY3_HUMAN TBC1 domain family member 31 (Fragm 0.065 16.3 0.1 3.9 10.7 0.0 2.3 1 tr|D6RGJ8|D6RGJ8_HUMAN WD repeat-containing protein 55 OS= 0.073 16.2 0.1 58 7.0 0.0 3.1 2 tr|D6RE64|D6RE64_HUMAN Protein transport protein Sec31A (F 0.075 16.1 0.1 58 7.0 0.0 3.1 2 tr|D6RCQ9|D6RCQ9_HUMAN Protein transport protein Sec31A (F 0.076 16.1 0.0 0.15 15.1 0.0 1.5 1 tr|A3KFI9|A3KFI9_HUMAN Cleavage stimulation factor subunit 0.076 16.1 1.3 0.093 15.8 0.4 1.6 1 tr|K7EL23|K7EL23_HUMAN Echinoderm microtubule-associated p 0.078 16.1 0.1 22 8.3 0.0 3.4 1 tr|H7C1Z3|H7C1Z3_HUMAN Nucleolar protein 10 (Fragment) OS= 0.081 16.0 0.0 0.11 15.6 0.0 1.2 1 tr|F8W7Y5|F8W7Y5_HUMAN WD repeat-containing protein 48 OS= 0.083 16.0 0.0 92 6.4 0.0 3.6 2 tr|G5EA37|G5EA37_HUMAN WD repeat domain phosphoinositide-i 0.086 15.9 1.1 0.11 15.6 0.1 1.7 1 tr|H7C0C5|H7C0C5_HUMAN THO complex subunit 3 (Fragment) OS 0.086 15.9 0.0 0.1 15.7 0.0 1.3 1 tr|F8VZB3|F8VZB3_HUMAN Protein POC1B-GALNT4 OS=Homo sapien 0.088 15.9 1.1 0.26 14.4 0.6 2.0 1 tr|Q5TDQ5|Q5TDQ5_HUMAN Peroxisomal targeting signal 2 rece 0.09 15.9 0.9 33 7.8 1.0 3.9 1 sp|Q6P1M3-3|L2GL2_HUMAN Isoform B of Lethal(2) giant larvae 0.1 15.7 0.0 0.16 15.1 0.0 1.3 1 tr|F8W6P2|F8W6P2_HUMAN WD repeat-containing protein 48 OS= 0.11 15.5 0.2 2.8 11.2 0.0 3.5 1 sp|Q96RY7|IF140_HUMAN Intraflagellar transport protein 14 0.12 15.5 0.1 0.14 15.3 0.1 1.1 1 tr|E5RI27|E5RI27_HUMAN TBC1 domain family member 31 (Fragm 0.13 15.3 0.0 0.14 15.3 0.0 1.3 1 tr|F8VV91|F8VV91_HUMAN POC1 centriolar protein homolog B O 0.14 15.3 1.9 19 8.5 0.2 4.4 1 sp|Q9NXC5-2|MIO_HUMAN Isoform 2 of WD repeat-containing p 0.14 15.3 0.1 0.29 14.3 0.1 1.6 1 tr|F5GY56|F5GY56_HUMAN Pre-mRNA-processing factor 19 (Frag 0.15 15.2 0.1 0.63 13.2 0.0 2.1 1 tr|K7EKB0|K7EKB0_HUMAN Breast carcinoma-amplified sequence 0.17 15.0 1.0 31 7.8 0.0 4.0 1 sp|Q9NRJ4-2|TULP4_HUMAN Isoform 2 of Tubby-related protein 0.17 15.0 1.6 1.5 12.0 0.4 3.2 1 tr|H7BXC4|H7BXC4_HUMAN Syntaxin binding protein 5 (Tomosyn 0.21 14.7 0.1 0.47 13.6 0.0 1.6 1 tr|F5GX79|F5GX79_HUMAN Elongator complex protein 2 (Fragme 0.24 14.5 3.5 55 7.1 0.1 3.7 2 sp|Q6P4I2|WDR73_HUMAN WD repeat-containing protein 73 OS= 0.24 14.5 1.0 2.3e+02 5.1 0.0 3.2 2 tr|D6RE75|D6RE75_HUMAN WD repeat-containing protein 19 (Fr 0.3 14.2 0.1 1.3 12.2 0.0 2.0 1 tr|I3L3A5|I3L3A5_HUMAN WD repeat domain phosphoinositide-i 0.31 14.2 0.0 0.7 13.1 0.0 1.6 1 sp|O75529-2|TAF5L_HUMAN Isoform 2 of TAF5-like RNA polymera 0.36 14.0 0.1 0.83 12.8 0.1 1.6 1 tr|H0YLI3|H0YLI3_HUMAN Transducin-like enhancer protein 3 0.37 13.9 0.1 2.6 11.2 0.0 2.4 1 tr|D6RAP6|D6RAP6_HUMAN Anaphase-promoting complex subunit 0.37 13.9 0.0 0.95 12.6 0.0 1.7 1 tr|G3V2K8|G3V2K8_HUMAN WD repeat-containing protein 25 OS= 0.38 13.9 3.8 29 8.0 0.0 4.3 1 sp|Q9H977|WDR54_HUMAN WD repeat-containing protein 54 OS= 0.4 13.8 0.0 1 12.5 0.0 1.7 1 tr|G3V367|G3V367_HUMAN WD repeat-containing protein 25 OS= 0.41 13.8 0.0 0.81 12.9 0.0 1.5 1 tr|K7ERR2|K7ERR2_HUMAN Echinoderm microtubule-associated p 0.44 13.7 0.1 7.6 9.8 0.1 2.4 1 tr|C9J627|C9J627_HUMAN Intraflagellar transport protein 80 0.48 13.6 0.1 1.2 12.4 0.1 1.7 1 tr|H7C4E4|H7C4E4_HUMAN Transducin-like enhancer protein 4 0.5 13.5 7.7 4.7 10.4 0.7 4.5 2 tr|B4E2F0|B4E2F0_HUMAN Nucleoporin Nup43 OS=Homo sapiens G 0.52 13.5 0.1 41 7.5 0.0 3.3 1 tr|C9J0A8|C9J0A8_HUMAN WD repeat domain phosphoinositide-i 0.56 13.4 0.3 2.9 11.1 0.2 2.2 1 tr|C9JTV2|C9JTV2_HUMAN WD repeat-containing protein mio (F 0.61 13.2 0.0 1.1 12.4 0.0 1.5 1 tr|H0YN92|H0YN92_HUMAN DDB1- and CUL4-associated factor 11 0.64 13.2 0.1 1.9e+02 5.4 0.2 4.3 1 tr|Q5TA04|Q5TA04_HUMAN WD repeat-containing protein 96 OS= 0.66 13.1 0.0 1.3e+02 5.9 0.0 2.6 2 tr|F5GXJ6|F5GXJ6_HUMAN Serine/threonine-protein phosphatas 0.7 13.1 0.0 1.3 12.2 0.0 1.4 1 sp|Q9NV06-2|DCA13_HUMAN Isoform 2 of DDB1- and CUL4-associa 0.72 13.0 0.0 2.4 11.4 0.0 1.9 1 sp|Q8WUA4-2|TF3C2_HUMAN Isoform 2 of General transcription 0.83 12.8 0.0 38 7.6 0.0 3.0 1 sp|Q9BSC4-2|NOL10_HUMAN Isoform 2 of Nucleolar protein 10 O 0.89 12.7 6.2 16 8.7 0.1 3.3 2 tr|H0YL77|H0YL77_HUMAN Uncharacterized protein (Fragment) 1 12.6 1.1 15 8.8 0.0 2.9 1 tr|M0R0E3|M0R0E3_HUMAN SH3KBP1-binding protein 1 (Fragment 1 12.5 0.0 2.2 11.5 0.0 1.6 1 tr|K7ERN7|K7ERN7_HUMAN Notchless protein homolog 1 OS=Homo 1.1 12.4 1.3 14 8.9 0.0 2.9 1 tr|M0QYB1|M0QYB1_HUMAN SH3KBP1-binding protein 1 (Fragment 1.8 11.7 8.1 3.9 10.7 0.3 4.1 2 sp|Q5MNZ6|WIPI3_HUMAN WD repeat domain phosphoinositide-i 2 11.6 6.0 14 8.9 0.5 3.6 1 tr|H0Y4P4|H0Y4P4_HUMAN EF-hand calcium-binding domain-cont Domain annotation for each sequence (and alignments): >> tr|G5EA46|G5EA46_HUMAN Dynein assembly factor with WDR repeat domains 1 OS=Homo sapiens GN=DAW1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 8.5e-06 0.00069 4 38 .] 70 105 .. 67 105 .. 0.92 2 ! 26.9 0.0 3.8e-07 3.1e-05 2 38 .] 110 148 .. 109 148 .. 0.92 3 ! 38.7 0.1 7.1e-11 5.7e-09 1 38 [] 152 190 .. 152 190 .. 0.95 4 ! 29.6 0.1 5.2e-08 4.2e-06 2 38 .] 195 232 .. 194 232 .. 0.90 5 ! 26.3 0.5 5.6e-07 4.6e-05 2 38 .] 237 274 .. 236 274 .. 0.92 6 ! 24.3 0.1 2.3e-06 0.00019 1 37 [. 278 315 .. 278 316 .. 0.92 7 ! 33.6 0.0 2.7e-09 2.2e-07 2 38 .] 321 358 .. 320 358 .. 0.95 8 ! 35.7 0.1 6.1e-10 5e-08 1 37 [. 362 399 .. 362 400 .] 0.94 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 8.5e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l++H + t +a +++g+ +++Gs+D+t+++Wd tr|G5EA46|G5EA46_HUMAN 70 FKVLKAHiLPLTNVALNKSGSCFITGSYDRTCKLWD 105 57899**8889************************9 PP == domain 2 score: 26.9 bits; conditional E-value: 3.8e-07 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 + l tl+GH + v+++a ++p+g+ +a+Gs D+t+++W+ tr|G5EA46|G5EA46_HUMAN 110 EELNTLEGHrNVVYAIAfNNPYGDKIATGSFDKTCKLWS 148 6789*****7769*************************5 PP == domain 3 score: 38.7 bits; conditional E-value: 7.1e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c +t++GH + +l+f+p ++++a+Gs+D t ++Wd tr|G5EA46|G5EA46_HUMAN 152 GKCYHTFRGHtAEIVCLSFNPQSTLVATGSMDTTAKLWD 190 79********76699***********************9 PP == domain 4 score: 29.6 bits; conditional E-value: 5.2e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + ++tl+GHs + sl+f+ +g+ +++Gs D+tv +Wd tr|G5EA46|G5EA46_HUMAN 195 EEVYTLRGHSAeIISLSFNTSGDRIITGSFDHTVVVWD 232 7899*****44588***********************9 PP == domain 5 score: 26.3 bits; conditional E-value: 5.6e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +l GH ++s +f+ d +++++Gs+D+t+++Wd tr|G5EA46|G5EA46_HUMAN 237 RKVNILIGHcAEISSASFNWDCSLILTGSMDKTCKLWD 274 678899***666*************************9 PP == domain 6 score: 24.3 bits; conditional E-value: 2.3e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+c+ tltGH + + + +f+ g+++a++s Dgt ri+ tr|G5EA46|G5EA46_HUMAN 278 GKCVATLTGHdDEILDSCFDYTGKLIATASADGTARIF 315 79********555*9999******************97 PP == domain 7 score: 33.6 bits; conditional E-value: 2.7e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ +l+GH + ++ ++f+p g+ l++Gs D+t riWd tr|G5EA46|G5EA46_HUMAN 321 KCIAKLEGHeGEISKISFNPQGNHLLTGSSDKTARIWD 358 89*******888****************99*******9 PP == domain 8 score: 35.7 bits; conditional E-value: 6.1e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 gqcl++l+GH + + s+af+ g+ +++Gs+D+t+riW tr|G5EA46|G5EA46_HUMAN 362 GQCLQVLEGHtDEIFSCAFNYKGNIVITGSKDNTCRIW 399 79********666************************* PP >> sp|Q8N136|DAW1_HUMAN Dynein assembly factor with WDR repeat domains 1 OS=Homo sapiens GN=DAW1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.0 9e-06 0.00073 4 38 .] 85 120 .. 82 120 .. 0.92 2 ! 26.8 0.0 4e-07 3.2e-05 2 38 .] 125 163 .. 124 163 .. 0.92 3 ! 38.6 0.1 7.4e-11 6e-09 1 38 [] 167 205 .. 167 205 .. 0.95 4 ! 29.5 0.1 5.5e-08 4.5e-06 2 38 .] 210 247 .. 209 247 .. 0.90 5 ! 26.2 0.5 5.9e-07 4.8e-05 2 38 .] 252 289 .. 251 289 .. 0.92 6 ! 24.3 0.1 2.5e-06 0.0002 1 37 [. 293 330 .. 293 331 .. 0.92 7 ! 33.6 0.0 2.8e-09 2.3e-07 2 38 .] 336 373 .. 335 373 .. 0.95 8 ! 35.6 0.1 6.5e-10 5.2e-08 1 37 [. 377 414 .. 377 415 .] 0.94 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 9e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l++H + t +a +++g+ +++Gs+D+t+++Wd sp|Q8N136|DAW1_HUMAN 85 FKVLKAHiLPLTNVALNKSGSCFITGSYDRTCKLWD 120 57899**8889************************9 PP == domain 2 score: 26.8 bits; conditional E-value: 4e-07 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 + l tl+GH + v+++a ++p+g+ +a+Gs D+t+++W+ sp|Q8N136|DAW1_HUMAN 125 EELNTLEGHrNVVYAIAfNNPYGDKIATGSFDKTCKLWS 163 6789*****7769*************************5 PP == domain 3 score: 38.6 bits; conditional E-value: 7.4e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c +t++GH + +l+f+p ++++a+Gs+D t ++Wd sp|Q8N136|DAW1_HUMAN 167 GKCYHTFRGHtAEIVCLSFNPQSTLVATGSMDTTAKLWD 205 79********76699***********************9 PP == domain 4 score: 29.5 bits; conditional E-value: 5.5e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + ++tl+GHs + sl+f+ +g+ +++Gs D+tv +Wd sp|Q8N136|DAW1_HUMAN 210 EEVYTLRGHSAeIISLSFNTSGDRIITGSFDHTVVVWD 247 7899*****44588***********************9 PP == domain 5 score: 26.2 bits; conditional E-value: 5.9e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +l GH ++s +f+ d +++++Gs+D+t+++Wd sp|Q8N136|DAW1_HUMAN 252 RKVNILIGHcAEISSASFNWDCSLILTGSMDKTCKLWD 289 678899***666*************************9 PP == domain 6 score: 24.3 bits; conditional E-value: 2.5e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+c+ tltGH + + + +f+ g+++a++s Dgt ri+ sp|Q8N136|DAW1_HUMAN 293 GKCVATLTGHdDEILDSCFDYTGKLIATASADGTARIF 330 79********555*9999******************97 PP == domain 7 score: 33.6 bits; conditional E-value: 2.8e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ +l+GH + ++ ++f+p g+ l++Gs D+t riWd sp|Q8N136|DAW1_HUMAN 336 KCIAKLEGHeGEISKISFNPQGNHLLTGSSDKTARIWD 373 89*******888****************99*******9 PP == domain 8 score: 35.6 bits; conditional E-value: 6.5e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 gqcl++l+GH + + s+af+ g+ +++Gs+D+t+riW sp|Q8N136|DAW1_HUMAN 377 GQCLQVLEGHtDEIFSCAFNYKGNIVITGSKDNTCRIW 414 79********666************************* PP >> sp|Q9NVX2|NLE1_HUMAN Notchless protein homolog 1 OS=Homo sapiens GN=NLE1 PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.7 0.1 1.4e-10 1.1e-08 2 38 .] 105 142 .. 104 142 .. 0.91 2 ! 28.6 0.8 1e-07 8.4e-06 5 38 .] 150 184 .. 146 184 .. 0.91 3 ! 29.2 0.2 6.8e-08 5.5e-06 3 38 .] 191 232 .. 189 232 .. 0.85 4 ! 31.0 0.2 1.8e-08 1.5e-06 1 37 [. 236 272 .. 236 273 .. 0.90 5 ? 10.5 0.1 0.057 4.6 4 38 .] 280 357 .. 277 357 .. 0.85 6 ! 29.3 0.0 6.4e-08 5.2e-06 2 38 .] 363 400 .. 362 400 .. 0.91 7 ! 33.9 0.2 2.3e-09 1.9e-07 1 38 [] 404 442 .. 404 442 .. 0.94 8 ! 33.6 0.0 2.8e-09 2.3e-07 6 37 .. 451 483 .. 446 484 .. 0.90 Alignments for each domain: == domain 1 score: 37.7 bits; conditional E-value: 1.4e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ +l+GH v s+afsp g++lasGs D tvr+Wd sp|Q9NVX2|NLE1_HUMAN 105 RCTSSLEGHsEAVISVAFSPTGKYLASGSGDTTVRFWD 142 6999*****54488**************99*******9 PP == domain 2 score: 28.6 bits; conditional E-value: 1e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t++GH +v s+++spdg+ lasG+++g + +Wd sp|Q9NVX2|NLE1_HUMAN 150 FTCKGHrHWVLSISWSPDGRKLASGCKNGQILLWD 184 5789**777*************************9 PP == domain 3 score: 29.2 bits; conditional E-value: 6.8e-08 EEEEEESS.SSEEEEE.....EETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtsla.....fspdgawlasGsdDgtvriWd 38 rtl GH +++t+l+ +p+ +++as+s+Dg+vriWd sp|Q9NVX2|NLE1_HUMAN 191 VGRTLAGHsKWITGLSweplhANPECRYVASSSKDGSVRIWD 232 56899***999****9777777777777*************9 PP == domain 4 score: 31.0 bits; conditional E-value: 1.8e-08 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+c r+ltGH +svt+l++ dg + s+s D+t+++W sp|Q9NVX2|NLE1_HUMAN 236 GRCERILTGHtQSVTCLRWGGDGLL-YSASQDRTIKVW 272 6899******999****88888877.89********** PP == domain 5 score: 10.5 bits; conditional E-value: 0.057 EEEEESS.SSEEEEEEETTSSE..........................................EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw..........................................lasGsdDgtvriWd 38 rtl GH +v+ +a s d a+ l+sGsdD t+ +W+ sp|Q9NVX2|NLE1_HUMAN 280 CRTLQGHgHWVNTMALSTDYALrtgafepaeasvnpqdlqgslqelkeralsrynlvrgqgperLVSGSDDFTLFLWS 357 578999944599999888888888888888888999999999999999999999999999999999***********5 PP == domain 6 score: 29.3 bits; conditional E-value: 6.4e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+ tGH+ ++ + fspd++ +as+s D+++++Wd sp|Q9NVX2|NLE1_HUMAN 363 KPLTRMTGHQAlINQVLFSPDSRIVASASFDKSIKLWD 400 6778889**6679***************99*******9 PP == domain 7 score: 33.9 bits; conditional E-value: 2.3e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+ l +l+GH v+ +a+s d+++l+sGs D t+++Wd sp|Q9NVX2|NLE1_HUMAN 404 GKYLASLRGHvAAVYQIAWSADSRLLVSGSSDSTLKVWD 442 577999****999****************99*******9 PP == domain 8 score: 33.6 bits; conditional E-value: 2.8e-09 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH + v+++++spdg+ +asG++D+ +riW sp|Q9NVX2|NLE1_HUMAN 451 DLPGHaDEVYAVDWSPDGQRVASGGKDKCLRIW 483 488**777************************* PP >> tr|J3KNC1|J3KNC1_HUMAN Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens GN=EML5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.0 0.0039 0.32 4 38 .] 54 91 .. 51 91 .. 0.90 2 ? 8.7 0.4 0.2 17 8 38 .] 105 136 .. 96 136 .. 0.77 3 ? 11.0 0.0 0.039 3.2 9 38 .] 235 263 .. 226 263 .. 0.67 4 ! 24.6 0.0 1.9e-06 0.00016 3 38 .] 316 353 .. 314 353 .. 0.86 5 ? 10.1 0.0 0.076 6.2 10 34 .. 403 432 .. 397 435 .. 0.84 6 ? 4.2 0.0 5.5 4.5e+02 2 25 .. 446 466 .. 442 468 .. 0.82 7 ! 23.0 1.9 6.2e-06 0.0005 3 38 .] 555 592 .. 553 592 .. 0.87 8 ! 23.8 0.1 3.5e-06 0.00029 2 38 .] 718 757 .. 717 757 .. 0.92 9 ! 20.2 0.3 4.8e-05 0.0039 2 38 .] 762 802 .. 761 802 .. 0.86 10 ? 8.7 0.0 0.21 17 4 38 .] 858 891 .. 856 891 .. 0.77 11 ! 20.5 0.0 4e-05 0.0032 8 38 .] 956 988 .. 950 988 .. 0.89 12 ? 5.4 0.1 2.3 1.8e+02 14 33 .. 1006 1025 .. 1004 1028 .. 0.88 13 ? 10.7 0.2 0.049 4 6 37 .. 1195 1228 .. 1190 1229 .. 0.86 14 ? 9.1 0.1 0.15 12 10 37 .. 1430 1460 .. 1420 1461 .. 0.76 15 ! 25.8 0.2 7.9e-07 6.4e-05 8 38 .] 1652 1684 .. 1646 1684 .. 0.89 16 ? 8.6 0.0 0.23 18 13 34 .. 1742 1763 .. 1728 1767 .. 0.83 17 ? 5.3 0.1 2.4 2e+02 5 31 .. 1843 1871 .. 1840 1879 .. 0.77 18 ! 13.7 0.7 0.0055 0.45 7 38 .] 1892 1925 .. 1887 1925 .. 0.78 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.0039 EEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++ ++GH +++ sla +p+ ++a+G ++ + + iWd tr|J3KNC1|J3KNC1_HUMAN 54 QKFYRGHsDDIISLALHPERVLVATGqvGKEPYICIWD 91 6779***66688**************999********9 PP == domain 2 score: 8.7 bits; conditional E-value: 0.2 ESSSSEEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlas.G..sdDgtvriWd 38 +H ++ +laf+ dg+ l+s G s ++ v +Wd tr|J3KNC1|J3KNC1_HUMAN 105 HTH-GIACLAFDLDGQRLVSvGldS-KNAVCVWD 136 356.7************99625645.*******9 PP == domain 3 score: 11.0 bits; conditional E-value: 0.039 SS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +H ++ s+ + +a+G++Dg +r+Wd tr|J3KNC1|J3KNC1_HUMAN 235 AHaAGIFSM--N----AceegFATGGRDGCIRLWD 263 555556666..2....2234479***********9 PP == domain 4 score: 24.6 bits; conditional E-value: 1.9e-06 EEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 + + GH + ++la++p +++ ++GsdD++vriW+ tr|J3KNC1|J3KNC1_HUMAN 316 PFLIMQGHcEGeLWALAVHPTKPLAVTGSDDRSVRIWS 353 566778**7336*************************5 PP == domain 5 score: 10.1 bits; conditional E-value: 0.076 S.SS....EEEEEEETTSSEEEEEETTSEE CS WD40 10 H.ss....vtslafspdgawlasGsdDgtv 34 H ++ ++ l++spdg++la G+ D +v tr|J3KNC1|J3KNC1_HUMAN 403 HiKDrkeaIHELKYSPDGTYLAVGCNDSSV 432 66556667999*************999987 PP == domain 6 score: 4.2 bits; conditional E-value: 5.5 EEEEEEESSSSEEEEEEETTSSEE CS WD40 2 qclrtltGHssvtslafspdgawl 25 +cl++l+ ++t+l++s+d+++l tr|J3KNC1|J3KNC1_HUMAN 446 ECLGSLS---FITHLDWSSDSRYL 466 5666666...8**********996 PP == domain 7 score: 23.0 bits; conditional E-value: 6.2e-06 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriWd 38 + r++ GH +vt +++s+d +w++s G+ D++v W+ tr|J3KNC1|J3KNC1_HUMAN 555 KFRKYIGHsAHVTNVRWSHDYQWVISiGGADHSVFQWK 592 578999**777************9755888*******5 PP == domain 8 score: 23.8 bits; conditional E-value: 3.5e-06 EEEEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 +++r + GH +++ +l +p ++++a+G ++D++++iWd tr|J3KNC1|J3KNC1_HUMAN 718 NTQRFYLGHdDDILCLTIHPLKDYVATGqvGRDPSIHIWD 757 5688899**888****************9999*******9 PP == domain 9 score: 20.2 bits; conditional E-value: 4.8e-05 EEEEEEESS.SS.EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ss.vtslafspdgawlasG..sdDgtvriWd 38 ++l +l+GH + v++++fs dg+ las +d +tv +Wd tr|J3KNC1|J3KNC1_HUMAN 762 KPLSILKGHhQYgVSAVDFSADGKRLASVgiDDSHTVVLWD 802 6899*****6448*************9752659*******9 PP == domain 10 score: 8.7 bits; conditional E-value: 0.21 EEEEESS.SSEEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw...lasGsdDgtvriWd 38 ++t ++H ++v s+ +a+ +++G++Dg v +Wd tr|J3KNC1|J3KNC1_HUMAN 858 VKTVKAHdGPVFSM-----HALekgFVTGGKDGIVALWD 891 68899997779777.....333444679**********9 PP == domain 11 score: 20.5 bits; conditional E-value: 4e-05 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 GH + v++la++p+ + a+ sdD+t+riWd tr|J3KNC1|J3KNC1_HUMAN 956 QGHmeGEVWGLATHPYLPICATVSDDKTLRIWD 988 6999555**************99*********9 PP == domain 12 score: 5.4 bits; conditional E-value: 2.3 EEEEEETTSSEEEEEETTSE CS WD40 14 tslafspdgawlasGsdDgt 33 ++++fspdg+ la G Dg+ tr|J3KNC1|J3KNC1_HUMAN 1006 RCCCFSPDGKALAVGLNDGS 1025 599**********9977997 PP == domain 13 score: 10.7 bits; conditional E-value: 0.049 EEESS.SSEEEEEEETTSSEEEE.EETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlas.GsdDgtvriW 37 + +H ++vt +++ d ++l++ G+ D ++++W tr|J3KNC1|J3KNC1_HUMAN 1195 RYVAHsTHVTNVRWTYDDSMLVTlGGTDMSLMVW 1228 57799777*************988767******* PP == domain 14 score: 9.1 bits; conditional E-value: 0.15 S.SSEEEEEEETTSSEEEEEE.T.TSEEEEE CS WD40 10 H.ssvtslafspdgawlasGs.d.DgtvriW 37 H ++v+s++fs g++l+s + d +t+ iW tr|J3KNC1|J3KNC1_HUMAN 1430 HsKGVCSVSFSATGKLLLSVGlDpEHTITIW 1460 7788************997663579999999 PP == domain 15 score: 25.8 bits; conditional E-value: 7.9e-07 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 GH +++++la++p+ ++++s+ +Dgtvr+Wd tr|J3KNC1|J3KNC1_HUMAN 1652 NGHvdGPIWGLATHPSRDFFLSAAEDGTVRLWD 1684 69*9556*************************9 PP == domain 16 score: 8.6 bits; conditional E-value: 0.23 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 +++++fspd+++la Gs ++v tr|J3KNC1|J3KNC1_HUMAN 1742 IHDIRFSPDSRYLAVGSSENSV 1763 99**************866655 PP == domain 17 score: 5.3 bits; conditional E-value: 2.4 EEEESS..SS.EEEEEEETTSSEEEEEETT CS WD40 5 rtltGH..ss.vtslafspdgawlasGsdD 31 ++++ H + v++ ++s++g l++G+ D tr|J3KNC1|J3KNC1_HUMAN 1843 GIWSRHaeKAdVNCACVSHSGISLVTGD-D 1871 56677866336***************98.4 PP == domain 18 score: 13.7 bits; conditional E-value: 0.0055 EESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawla.sGsdDgtvriWd 38 + GHs+ vt ++f + + ++ +G+dD+++ +W+ tr|J3KNC1|J3KNC1_HUMAN 1892 FLGHSPhVTNIRFTSGDRHVVsAGGDDCSLFVWK 1925 559*667*****7777777663779********6 PP >> sp|Q05BV3|EMAL5_HUMAN Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens GN=EML5 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.0 0.004 0.33 4 38 .] 54 91 .. 51 91 .. 0.90 2 ? 8.7 0.4 0.21 17 8 38 .] 105 136 .. 96 136 .. 0.77 3 ? 11.0 0.0 0.04 3.2 9 38 .] 235 263 .. 226 263 .. 0.67 4 ! 24.6 0.0 2e-06 0.00016 3 38 .] 316 353 .. 314 353 .. 0.86 5 ? 10.0 0.0 0.078 6.3 10 34 .. 403 432 .. 397 435 .. 0.84 6 ? 4.2 0.0 5.6 4.6e+02 2 25 .. 446 466 .. 442 468 .. 0.82 7 ! 23.0 1.9 6.3e-06 0.00051 3 38 .] 555 592 .. 553 592 .. 0.87 8 ! 23.7 0.1 3.6e-06 0.00029 2 38 .] 718 757 .. 717 757 .. 0.92 9 ! 20.2 0.3 4.9e-05 0.004 2 38 .] 762 802 .. 761 802 .. 0.86 10 ? 8.7 0.0 0.21 17 4 38 .] 896 929 .. 894 929 .. 0.77 11 ! 20.4 0.0 4e-05 0.0033 8 38 .] 994 1026 .. 988 1026 .. 0.89 12 ? 5.4 0.1 2.3 1.9e+02 14 33 .. 1044 1063 .. 1042 1066 .. 0.88 13 ? 10.6 0.2 0.05 4.1 6 37 .. 1233 1266 .. 1228 1267 .. 0.86 14 ? 9.1 0.1 0.15 12 10 37 .. 1468 1498 .. 1458 1499 .. 0.76 15 ! 25.8 0.2 8.1e-07 6.6e-05 8 38 .] 1690 1722 .. 1684 1722 .. 0.89 16 ? 8.5 0.0 0.23 19 13 34 .. 1780 1801 .. 1766 1805 .. 0.83 17 ? 5.3 0.1 2.5 2e+02 5 31 .. 1881 1909 .. 1878 1917 .. 0.77 18 ! 13.6 0.7 0.0056 0.46 7 38 .] 1930 1963 .. 1925 1963 .. 0.78 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.004 EEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++ ++GH +++ sla +p+ ++a+G ++ + + iWd sp|Q05BV3|EMAL5_HUMAN 54 QKFYRGHsDDIISLALHPERVLVATGqvGKEPYICIWD 91 6779***66688**************999********9 PP == domain 2 score: 8.7 bits; conditional E-value: 0.21 ESSSSEEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlas.G..sdDgtvriWd 38 +H ++ +laf+ dg+ l+s G s ++ v +Wd sp|Q05BV3|EMAL5_HUMAN 105 HTH-GIACLAFDLDGQRLVSvGldS-KNAVCVWD 136 356.7************99625645.*******9 PP == domain 3 score: 11.0 bits; conditional E-value: 0.04 SS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +H ++ s+ + +a+G++Dg +r+Wd sp|Q05BV3|EMAL5_HUMAN 235 AHaAGIFSM--N----AceegFATGGRDGCIRLWD 263 555556666..2....2234479***********9 PP == domain 4 score: 24.6 bits; conditional E-value: 2e-06 EEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 + + GH + ++la++p +++ ++GsdD++vriW+ sp|Q05BV3|EMAL5_HUMAN 316 PFLIMQGHcEGeLWALAVHPTKPLAVTGSDDRSVRIWS 353 566778**7336*************************5 PP == domain 5 score: 10.0 bits; conditional E-value: 0.078 S.SS....EEEEEEETTSSEEEEEETTSEE CS WD40 10 H.ss....vtslafspdgawlasGsdDgtv 34 H ++ ++ l++spdg++la G+ D +v sp|Q05BV3|EMAL5_HUMAN 403 HiKDrkeaIHELKYSPDGTYLAVGCNDSSV 432 66556667999*************999987 PP == domain 6 score: 4.2 bits; conditional E-value: 5.6 EEEEEEESSSSEEEEEEETTSSEE CS WD40 2 qclrtltGHssvtslafspdgawl 25 +cl++l+ ++t+l++s+d+++l sp|Q05BV3|EMAL5_HUMAN 446 ECLGSLS---FITHLDWSSDSRYL 466 5666666...8**********996 PP == domain 7 score: 23.0 bits; conditional E-value: 6.3e-06 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriWd 38 + r++ GH +vt +++s+d +w++s G+ D++v W+ sp|Q05BV3|EMAL5_HUMAN 555 KFRKYIGHsAHVTNVRWSHDYQWVISiGGADHSVFQWK 592 578999**777************9755888*******5 PP == domain 8 score: 23.7 bits; conditional E-value: 3.6e-06 EEEEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 +++r + GH +++ +l +p ++++a+G ++D++++iWd sp|Q05BV3|EMAL5_HUMAN 718 NTQRFYLGHdDDILCLTIHPLKDYVATGqvGRDPSIHIWD 757 5688899**888****************9999*******9 PP == domain 9 score: 20.2 bits; conditional E-value: 4.9e-05 EEEEEEESS.SS.EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ss.vtslafspdgawlasG..sdDgtvriWd 38 ++l +l+GH + v++++fs dg+ las +d +tv +Wd sp|Q05BV3|EMAL5_HUMAN 762 KPLSILKGHhQYgVSAVDFSADGKRLASVgiDDSHTVVLWD 802 6899*****6448*************9752659*******9 PP == domain 10 score: 8.7 bits; conditional E-value: 0.21 EEEEESS.SSEEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw...lasGsdDgtvriWd 38 ++t ++H ++v s+ +a+ +++G++Dg v +Wd sp|Q05BV3|EMAL5_HUMAN 896 VKTVKAHdGPVFSM-----HALekgFVTGGKDGIVALWD 929 68899997779777.....333444679**********9 PP == domain 11 score: 20.4 bits; conditional E-value: 4e-05 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 GH + v++la++p+ + a+ sdD+t+riWd sp|Q05BV3|EMAL5_HUMAN 994 QGHmeGEVWGLATHPYLPICATVSDDKTLRIWD 1026 6999555**************99*********9 PP == domain 12 score: 5.4 bits; conditional E-value: 2.3 EEEEEETTSSEEEEEETTSE CS WD40 14 tslafspdgawlasGsdDgt 33 ++++fspdg+ la G Dg+ sp|Q05BV3|EMAL5_HUMAN 1044 RCCCFSPDGKALAVGLNDGS 1063 599**********9977997 PP == domain 13 score: 10.6 bits; conditional E-value: 0.05 EEESS.SSEEEEEEETTSSEEEE.EETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlas.GsdDgtvriW 37 + +H ++vt +++ d ++l++ G+ D ++++W sp|Q05BV3|EMAL5_HUMAN 1233 RYVAHsTHVTNVRWTYDDSMLVTlGGTDMSLMVW 1266 57799777*************988767******* PP == domain 14 score: 9.1 bits; conditional E-value: 0.15 S.SSEEEEEEETTSSEEEEEE.T.TSEEEEE CS WD40 10 H.ssvtslafspdgawlasGs.d.DgtvriW 37 H ++v+s++fs g++l+s + d +t+ iW sp|Q05BV3|EMAL5_HUMAN 1468 HsKGVCSVSFSATGKLLLSVGlDpEHTITIW 1498 7788************997663579999999 PP == domain 15 score: 25.8 bits; conditional E-value: 8.1e-07 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 GH +++++la++p+ ++++s+ +Dgtvr+Wd sp|Q05BV3|EMAL5_HUMAN 1690 NGHvdGPIWGLATHPSRDFFLSAAEDGTVRLWD 1722 69*9556*************************9 PP == domain 16 score: 8.5 bits; conditional E-value: 0.23 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 +++++fspd+++la Gs ++v sp|Q05BV3|EMAL5_HUMAN 1780 IHDIRFSPDSRYLAVGSSENSV 1801 99**************866655 PP == domain 17 score: 5.3 bits; conditional E-value: 2.5 EEEESS..SS.EEEEEEETTSSEEEEEETT CS WD40 5 rtltGH..ss.vtslafspdgawlasGsdD 31 ++++ H + v++ ++s++g l++G+ D sp|Q05BV3|EMAL5_HUMAN 1881 GIWSRHaeKAdVNCACVSHSGISLVTGD-D 1909 56677866336***************98.4 PP == domain 18 score: 13.6 bits; conditional E-value: 0.0056 EESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawla.sGsdDgtvriWd 38 + GHs+ vt ++f + + ++ +G+dD+++ +W+ sp|Q05BV3|EMAL5_HUMAN 1930 FLGHSPhVTNIRFTSGDRHVVsAGGDDCSLFVWK 1963 559*667*****7777777663779********6 PP >> sp|Q05BV3-5|EMAL5_HUMAN Isoform 5 of Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens GN=EML5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.0 0.0041 0.33 4 38 .] 54 91 .. 51 91 .. 0.90 2 ? 8.7 0.4 0.21 17 8 38 .] 105 136 .. 96 136 .. 0.77 3 ? 10.9 0.0 0.04 3.3 9 38 .] 235 263 .. 226 263 .. 0.67 4 ! 24.6 0.0 2e-06 0.00016 3 38 .] 316 353 .. 314 353 .. 0.86 5 ? 10.0 0.0 0.078 6.3 10 34 .. 403 432 .. 397 435 .. 0.84 6 ? 4.1 0.0 5.6 4.6e+02 2 25 .. 446 466 .. 442 468 .. 0.82 7 ! 23.0 1.9 6.3e-06 0.00051 3 38 .] 555 592 .. 553 592 .. 0.87 8 ! 23.7 0.1 3.6e-06 0.00029 2 38 .] 718 757 .. 717 757 .. 0.92 9 ! 20.2 0.3 4.9e-05 0.004 2 38 .] 762 802 .. 761 802 .. 0.86 10 ? 8.6 0.0 0.21 17 4 38 .] 896 929 .. 894 929 .. 0.77 11 ! 20.4 0.0 4.1e-05 0.0033 8 38 .] 994 1026 .. 988 1026 .. 0.89 12 ? 5.4 0.1 2.3 1.9e+02 14 33 .. 1044 1063 .. 1042 1066 .. 0.88 13 ? 10.6 0.2 0.051 4.1 6 37 .. 1233 1266 .. 1228 1267 .. 0.86 14 ? 9.1 0.1 0.15 13 10 37 .. 1476 1506 .. 1466 1507 .. 0.76 15 ! 25.8 0.2 8.2e-07 6.6e-05 8 38 .] 1698 1730 .. 1692 1730 .. 0.89 16 ? 8.5 0.0 0.23 19 13 34 .. 1788 1809 .. 1774 1813 .. 0.83 17 ? 5.3 0.1 2.5 2e+02 5 31 .. 1889 1917 .. 1886 1925 .. 0.77 18 ! 13.6 0.7 0.0057 0.46 7 38 .] 1938 1971 .. 1933 1971 .. 0.78 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.0041 EEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++ ++GH +++ sla +p+ ++a+G ++ + + iWd sp|Q05BV3-5|EMAL5_HUMAN 54 QKFYRGHsDDIISLALHPERVLVATGqvGKEPYICIWD 91 6779***66688**************999********9 PP == domain 2 score: 8.7 bits; conditional E-value: 0.21 ESSSSEEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlas.G..sdDgtvriWd 38 +H ++ +laf+ dg+ l+s G s ++ v +Wd sp|Q05BV3-5|EMAL5_HUMAN 105 HTH-GIACLAFDLDGQRLVSvGldS-KNAVCVWD 136 356.7************99625645.*******9 PP == domain 3 score: 10.9 bits; conditional E-value: 0.04 SS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +H ++ s+ + +a+G++Dg +r+Wd sp|Q05BV3-5|EMAL5_HUMAN 235 AHaAGIFSM--N----AceegFATGGRDGCIRLWD 263 555556666..2....2234479***********9 PP == domain 4 score: 24.6 bits; conditional E-value: 2e-06 EEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 + + GH + ++la++p +++ ++GsdD++vriW+ sp|Q05BV3-5|EMAL5_HUMAN 316 PFLIMQGHcEGeLWALAVHPTKPLAVTGSDDRSVRIWS 353 566778**7336*************************5 PP == domain 5 score: 10.0 bits; conditional E-value: 0.078 S.SS....EEEEEEETTSSEEEEEETTSEE CS WD40 10 H.ss....vtslafspdgawlasGsdDgtv 34 H ++ ++ l++spdg++la G+ D +v sp|Q05BV3-5|EMAL5_HUMAN 403 HiKDrkeaIHELKYSPDGTYLAVGCNDSSV 432 66556667999*************999987 PP == domain 6 score: 4.1 bits; conditional E-value: 5.6 EEEEEEESSSSEEEEEEETTSSEE CS WD40 2 qclrtltGHssvtslafspdgawl 25 +cl++l+ ++t+l++s+d+++l sp|Q05BV3-5|EMAL5_HUMAN 446 ECLGSLS---FITHLDWSSDSRYL 466 5666666...8**********996 PP == domain 7 score: 23.0 bits; conditional E-value: 6.3e-06 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriWd 38 + r++ GH +vt +++s+d +w++s G+ D++v W+ sp|Q05BV3-5|EMAL5_HUMAN 555 KFRKYIGHsAHVTNVRWSHDYQWVISiGGADHSVFQWK 592 578999**777************9755888*******5 PP == domain 8 score: 23.7 bits; conditional E-value: 3.6e-06 EEEEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 +++r + GH +++ +l +p ++++a+G ++D++++iWd sp|Q05BV3-5|EMAL5_HUMAN 718 NTQRFYLGHdDDILCLTIHPLKDYVATGqvGRDPSIHIWD 757 5688899**888****************9999*******9 PP == domain 9 score: 20.2 bits; conditional E-value: 4.9e-05 EEEEEEESS.SS.EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ss.vtslafspdgawlasG..sdDgtvriWd 38 ++l +l+GH + v++++fs dg+ las +d +tv +Wd sp|Q05BV3-5|EMAL5_HUMAN 762 KPLSILKGHhQYgVSAVDFSADGKRLASVgiDDSHTVVLWD 802 6899*****6448*************9752659*******9 PP == domain 10 score: 8.6 bits; conditional E-value: 0.21 EEEEESS.SSEEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw...lasGsdDgtvriWd 38 ++t ++H ++v s+ +a+ +++G++Dg v +Wd sp|Q05BV3-5|EMAL5_HUMAN 896 VKTVKAHdGPVFSM-----HALekgFVTGGKDGIVALWD 929 68899997779777.....333444679**********9 PP == domain 11 score: 20.4 bits; conditional E-value: 4.1e-05 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 GH + v++la++p+ + a+ sdD+t+riWd sp|Q05BV3-5|EMAL5_HUMAN 994 QGHmeGEVWGLATHPYLPICATVSDDKTLRIWD 1026 6999555**************99*********9 PP == domain 12 score: 5.4 bits; conditional E-value: 2.3 EEEEEETTSSEEEEEETTSE CS WD40 14 tslafspdgawlasGsdDgt 33 ++++fspdg+ la G Dg+ sp|Q05BV3-5|EMAL5_HUMAN 1044 RCCCFSPDGKALAVGLNDGS 1063 599**********9977997 PP == domain 13 score: 10.6 bits; conditional E-value: 0.051 EEESS.SSEEEEEEETTSSEEEE.EETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlas.GsdDgtvriW 37 + +H ++vt +++ d ++l++ G+ D ++++W sp|Q05BV3-5|EMAL5_HUMAN 1233 RYVAHsTHVTNVRWTYDDSMLVTlGGTDMSLMVW 1266 57799777*************988767******* PP == domain 14 score: 9.1 bits; conditional E-value: 0.15 S.SSEEEEEEETTSSEEEEEE.T.TSEEEEE CS WD40 10 H.ssvtslafspdgawlasGs.d.DgtvriW 37 H ++v+s++fs g++l+s + d +t+ iW sp|Q05BV3-5|EMAL5_HUMAN 1476 HsKGVCSVSFSATGKLLLSVGlDpEHTITIW 1506 7788************997663579999999 PP == domain 15 score: 25.8 bits; conditional E-value: 8.2e-07 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 GH +++++la++p+ ++++s+ +Dgtvr+Wd sp|Q05BV3-5|EMAL5_HUMAN 1698 NGHvdGPIWGLATHPSRDFFLSAAEDGTVRLWD 1730 69*9556*************************9 PP == domain 16 score: 8.5 bits; conditional E-value: 0.23 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 +++++fspd+++la Gs ++v sp|Q05BV3-5|EMAL5_HUMAN 1788 IHDIRFSPDSRYLAVGSSENSV 1809 99**************866655 PP == domain 17 score: 5.3 bits; conditional E-value: 2.5 EEEESS..SS.EEEEEEETTSSEEEEEETT CS WD40 5 rtltGH..ss.vtslafspdgawlasGsdD 31 ++++ H + v++ ++s++g l++G+ D sp|Q05BV3-5|EMAL5_HUMAN 1889 GIWSRHaeKAdVNCACVSHSGISLVTGD-D 1917 56677866336***************98.4 PP == domain 18 score: 13.6 bits; conditional E-value: 0.0057 EESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawla.sGsdDgtvriWd 38 + GHs+ vt ++f + + ++ +G+dD+++ +W+ sp|Q05BV3-5|EMAL5_HUMAN 1938 FLGHSPhVTNIRFTSGDRHVVsAGGDDCSLFVWK 1971 559*667*****7777777663779********6 PP >> sp|Q6ZMW3|EMAL6_HUMAN Echinoderm microtubule-associated protein-like 6 OS=Homo sapiens GN=EML6 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 0.00061 0.049 4 38 .] 54 91 .. 51 91 .. 0.88 2 ! 16.3 0.3 0.00082 0.067 7 38 .] 104 136 .. 96 136 .. 0.80 3 ? 7.9 0.2 0.37 30 2 37 .. 141 177 .. 140 178 .. 0.82 4 ? 11.0 0.0 0.039 3.2 9 38 .] 235 263 .. 226 263 .. 0.66 5 ! 24.1 0.0 2.8e-06 0.00023 2 38 .] 315 353 .. 314 353 .. 0.89 6 ? 7.3 0.0 0.58 47 13 34 .. 369 390 .. 358 392 .. 0.87 7 ? 10.3 0.0 0.062 5.1 10 32 .. 403 430 .. 397 430 .. 0.85 8 ! 21.6 1.9 1.7e-05 0.0014 3 37 .. 555 591 .. 553 592 .. 0.87 9 ! 15.1 0.1 0.002 0.16 4 38 .] 720 757 .. 715 757 .. 0.89 10 ? 9.4 0.3 0.12 10 2 32 .. 762 795 .. 761 802 .. 0.75 11 ? 11.1 0.0 0.036 2.9 4 38 .] 896 929 .. 894 929 .. 0.76 12 ! 12.9 0.0 0.0094 0.76 8 37 .. 994 1025 .. 988 1026 .. 0.87 13 ? 5.4 0.1 2.2 1.8e+02 14 35 .. 1044 1065 .. 1043 1068 .. 0.87 14 ? 3.4 0.1 9.6 7.8e+02 3 31 .. 1183 1213 .. 1181 1216 .. 0.79 15 ! 13.3 0.3 0.0071 0.57 5 37 .. 1232 1266 .. 1229 1267 .. 0.81 16 ? 4.3 0.1 5.2 4.2e+02 9 37 .. 1460 1491 .. 1450 1492 .. 0.77 17 ! 24.0 0.2 3.1e-06 0.00025 8 38 .] 1683 1715 .. 1678 1715 .. 0.90 18 ? 3.9 0.0 6.7 5.4e+02 9 32 .. 1728 1750 .. 1720 1754 .. 0.81 19 ? 6.4 0.0 1.1 91 13 34 .. 1773 1794 .. 1759 1798 .. 0.85 20 ! 20.7 0.6 3.4e-05 0.0028 7 37 .. 1923 1955 .. 1917 1956 .. 0.86 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 0.00061 EEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++ + GH +++ sla +pd++++a+G ++ + + iWd sp|Q6ZMW3|EMAL6_HUMAN 54 QKFFLGHnDDIISLALHPDKTLVATGqvGKEPYICIWD 91 56678**66688**************999********9 PP == domain 2 score: 16.3 bits; conditional E-value: 0.00082 EESSSSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 7 ltGHssvtslafspdgawlasG..sdDgtvriWd 38 +H +v +laf++dg+ las + ++tv iWd sp|Q6ZMW3|EMAL6_HUMAN 104 VHTH-GVACLAFDSDGQRLASVglDAKNTVCIWD 136 4566.8*************9752546*******9 PP == domain 3 score: 7.9 bits; conditional E-value: 0.37 EEEEEEESSSS.EEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgaw.lasGsdDgtvriW 37 ++l + tGHs+ + +++++p+++ ++s++ +++++W sp|Q6ZMW3|EMAL6_HUMAN 141 KLLASATGHSDrIFDISWDPYQPNrVVSCG-VKHIKFW 177 6777889**556************988999.7777777 PP == domain 4 score: 11.0 bits; conditional E-value: 0.039 SS.SSEEEEEEETTSSE.....EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw.....lasGsdDgtvriWd 38 +H ++ s+ + +a+G++Dg +r+Wd sp|Q6ZMW3|EMAL6_HUMAN 235 AHsAGIFSM-------YaceegFATGGRDGCIRLWD 263 454446666.......333455799**********9 PP == domain 5 score: 24.1 bits; conditional E-value: 2.8e-06 EEEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 +++ +l GH + ++la +p +++ ++GsdD++vr+W+ sp|Q6ZMW3|EMAL6_HUMAN 315 KPMLILQGHcEGeLWALALHPKKPLAVTGSDDRSVRLWS 353 578899***7336*************************5 PP == domain 6 score: 7.3 bits; conditional E-value: 0.58 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 v+s+afspdg+ la G++Dg+ sp|Q6ZMW3|EMAL6_HUMAN 369 VRSVAFSPDGSQLALGMKDGSF 390 99**********9889999985 PP == domain 7 score: 10.3 bits; conditional E-value: 0.062 S.SS....EEEEEEETTSSEEEEEETTS CS WD40 10 H.ss....vtslafspdgawlasGsdDg 32 H ++ ++ ++fspdg++la Gs Dg sp|Q6ZMW3|EMAL6_HUMAN 403 HiKDrkevIHEMKFSPDGSYLAVGSNDG 430 666667767999*************997 PP == domain 8 score: 21.6 bits; conditional E-value: 1.7e-05 EEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla.sGsdDgtvriW 37 + r++ GH +vt +++s+d +w++ +G+ D++v W sp|Q6ZMW3|EMAL6_HUMAN 555 KFRKYVGHsAHVTNVRWSHDFQWVLsTGGADHSVFQW 591 578999**777************7648999******9 PP == domain 9 score: 15.1 bits; conditional E-value: 0.002 EEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 +r + GH +++ sl +p ++++a+G ++D +++Wd sp|Q6ZMW3|EMAL6_HUMAN 720 QRLYLGHdDDILSLTIHPVKDYVATGqvGRDAAIHVWD 757 45577**888****************9999*******9 PP == domain 10 score: 9.4 bits; conditional E-value: 0.12 EEEEEEESS.SS.EEEEEEETTSSEEEEEE.TTS CS WD40 2 qclrtltGH.ss.vtslafspdgawlasGs.dDg 32 +cl l+G+ + v++l+fs dg+ l+s + dD sp|Q6ZMW3|EMAL6_HUMAN 762 KCLSLLKGQhQRgVCALDFSADGKCLVSVGlDDF 795 6888899885336*************97553554 PP == domain 11 score: 11.1 bits; conditional E-value: 0.036 EEEEESS.SSE...EEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssv...tslafspdgawlasGsdDgtvriWd 38 l+t ++H ++v ++l d+ ++ +G++Dg v +Wd sp|Q6ZMW3|EMAL6_HUMAN 896 LKTVKAHdGPVfamYAL----DKGFV-TGGKDGIVELWD 929 78999997778333555....66665.8**********9 PP == domain 12 score: 12.9 bits; conditional E-value: 0.0094 ESS..SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriW 37 GH + v++la +p + a+ sdD+t+riW sp|Q6ZMW3|EMAL6_HUMAN 994 QGHmeGEVWGLAAHPLLPICATVSDDKTLRIW 1025 6999555************9999********* PP == domain 13 score: 5.4 bits; conditional E-value: 2.2 EEEEEETTSSEEEEEETTSEEE CS WD40 14 tslafspdgawlasGsdDgtvr 35 +++afspdg+ la G Dg+ sp|Q6ZMW3|EMAL6_HUMAN 1044 RCCAFSPDGKALAVGLNDGSFL 1065 59************97799865 PP == domain 14 score: 3.4 bits; conditional E-value: 9.6 EEEEEESSSSEEEEE...EETTSSEEEEEETT CS WD40 3 clrtltGHssvtsla...fspdgawlasGsdD 31 c +++ +Hs++t++ +d ++la+G+ D sp|Q6ZMW3|EMAL6_HUMAN 1183 CEGIWPAHSDITDVNaasLTKDCSLLATGD-D 1213 778899**8877776666999999999987.6 PP == domain 15 score: 13.3 bits; conditional E-value: 0.0071 EEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawla.sGsdDgtvriW 37 +++ GH +vt +++ ++ + l+ G+ D ++iW sp|Q6ZMW3|EMAL6_HUMAN 1232 KKYVGHsAHVTNVRWLHNDSVLLtVGGADTALMIW 1266 5789**777****977777776526899******* PP == domain 16 score: 4.3 bits; conditional E-value: 5.2 SS.SSEEEEEEETTSSEEEEEET..TSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsd..DgtvriW 37 H ++v+ + fs g++l+s + +t+ +W sp|Q6ZMW3|EMAL6_HUMAN 1460 FHsKGVNYINFSATGKLLVSVGVdpEHTITVW 1491 69888*************98775478888888 PP == domain 17 score: 24.0 bits; conditional E-value: 3.1e-06 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 +GH + +++la++p++++++s+s Dgt riWd sp|Q6ZMW3|EMAL6_HUMAN 1683 DGHmeGEIWGLATHPSKDLFISASNDGTARIWD 1715 69*9555*************************9 PP == domain 18 score: 3.9 bits; conditional E-value: 6.7 SSSSEEEEEEETTSSEEEEEETTS CS WD40 9 GHssvtslafspdgawlasGsdDg 32 GH ++ a+spdg ++a G+++g sp|Q6ZMW3|EMAL6_HUMAN 1728 GH-AARCAAYSPDGEMVAIGMKNG 1750 78.5699***********999776 PP == domain 19 score: 6.4 bits; conditional E-value: 1.1 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 + +++ spd+++la Gs +tv sp|Q6ZMW3|EMAL6_HUMAN 1773 IQDIRISPDNRFLAVGSSEHTV 1794 89999***********889988 PP == domain 20 score: 20.7 bits; conditional E-value: 3.4e-05 EESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawla.sGsdDgtvriW 37 + GH +vt ++fs d ++++ +G+dD++v +W sp|Q6ZMW3|EMAL6_HUMAN 1923 YFGHsAHVTNIRFSYDDKYVVsTGGDDCSVFVW 1955 4499777************875899******** PP >> sp|Q8NBT0-2|POC1A_HUMAN Isoform 2 of POC1 centriolar protein homolog A OS=Homo sapiens GN=POC1A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.7 0.1 2.2e-08 1.8e-06 4 37 .. 12 46 .. 9 47 .. 0.93 2 ! 43.2 0.1 2.7e-12 2.2e-10 6 37 .. 56 88 .. 51 89 .. 0.91 3 ! 26.5 0.5 5e-07 4.1e-05 5 37 .. 97 130 .. 94 130 .. 0.93 4 ! 39.1 0.2 4.9e-11 4e-09 3 38 .] 137 173 .. 135 173 .. 0.94 5 ! 35.0 0.2 1e-09 8.2e-08 2 38 .] 178 215 .. 177 215 .. 0.94 6 ! 24.2 0.1 2.6e-06 0.00021 3 36 .. 221 255 .. 219 257 .. 0.87 7 ! 24.8 0.0 1.6e-06 0.00013 1 38 [] 261 299 .. 261 299 .. 0.92 Alignments for each domain: == domain 1 score: 30.7 bits; conditional E-value: 2.2e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 r+++GH + vt+++fs + + lasGs+D +++W sp|Q8NBT0-2|POC1A_HUMAN 12 ERHFKGHrDAVTCVDFSINTKQLASGSMDSCLMVW 46 69*****888************************* PP == domain 2 score: 43.2 bits; conditional E-value: 2.7e-12 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriW 37 +tGH++ vt++ fsp+g++lasGs+D+tvriW sp|Q8NBT0-2|POC1A_HUMAN 56 RFTGHKDaVTCVNFSPSGHLLASGSRDKTVRIW 88 589**555************************* PP == domain 3 score: 26.5 bits; conditional E-value: 5e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++++H v+s+ f++dg+ ++++sdD+tv++W sp|Q8NBT0-2|POC1A_HUMAN 97 TVFRAHtATVRSVHFCSDGQSFVTASDDKTVKVW 130 579***777************************* PP == domain 4 score: 39.1 bits; conditional E-value: 4.9e-11 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l+ H ++v++ +fspdg++++s+sdD+tv++Wd sp|Q8NBT0-2|POC1A_HUMAN 137 FLFSLSQHiNWVRCAKFSPDGRLIVSASDDKTVKLWD 173 67899*******************************9 PP == domain 5 score: 35.0 bits; conditional E-value: 1e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c++++ H ++vt ++f+p+g+ +a++++D+tv++Wd sp|Q8NBT0-2|POC1A_HUMAN 178 ECVHSYCEHgGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215 8********777*************99999*******9 PP == domain 6 score: 24.2 bits; conditional E-value: 2.6e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +l+++ H v++l+f+p+g++l+++s D t++i sp|Q8NBT0-2|POC1A_HUMAN 221 LLQHYQLHsAAVNGLSFHPSGNYLITASSDSTLKI 255 68899999555**************9988*****9 PP == domain 7 score: 24.8 bits; conditional E-value: 1.6e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l+tl GH ++ t +afs+ g ++asG+ D v++W+ sp|Q8NBT0-2|POC1A_HUMAN 261 GRLLYTLHGHqGPATTVAFSRTGEYFASGGSDEQVMVWK 299 57899*****8889***************88*******6 PP >> sp|Q8NBT0|POC1A_HUMAN POC1 centriolar protein homolog A OS=Homo sapiens GN=POC1A PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.5 0.1 2.6e-08 2.1e-06 4 37 .. 12 46 .. 9 47 .. 0.93 2 ! 42.9 0.1 3.2e-12 2.6e-10 6 37 .. 56 88 .. 51 89 .. 0.91 3 ! 26.2 0.5 6e-07 4.8e-05 5 37 .. 97 130 .. 94 130 .. 0.93 4 ! 38.9 0.2 5.8e-11 4.7e-09 3 38 .] 137 173 .. 135 173 .. 0.94 5 ! 34.8 0.2 1.2e-09 9.7e-08 2 38 .] 178 215 .. 177 215 .. 0.94 6 ! 24.0 0.1 3e-06 0.00024 3 36 .. 221 255 .. 219 257 .. 0.87 7 ! 24.6 0.0 1.9e-06 0.00016 1 38 [] 261 299 .. 261 299 .. 0.92 Alignments for each domain: == domain 1 score: 30.5 bits; conditional E-value: 2.6e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 r+++GH + vt+++fs + + lasGs+D +++W sp|Q8NBT0|POC1A_HUMAN 12 ERHFKGHrDAVTCVDFSINTKQLASGSMDSCLMVW 46 69*****888************************* PP == domain 2 score: 42.9 bits; conditional E-value: 3.2e-12 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriW 37 +tGH++ vt++ fsp+g++lasGs+D+tvriW sp|Q8NBT0|POC1A_HUMAN 56 RFTGHKDaVTCVNFSPSGHLLASGSRDKTVRIW 88 589**555************************* PP == domain 3 score: 26.2 bits; conditional E-value: 6e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++++H v+s+ f++dg+ ++++sdD+tv++W sp|Q8NBT0|POC1A_HUMAN 97 TVFRAHtATVRSVHFCSDGQSFVTASDDKTVKVW 130 579***777************************* PP == domain 4 score: 38.9 bits; conditional E-value: 5.8e-11 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l+ H ++v++ +fspdg++++s+sdD+tv++Wd sp|Q8NBT0|POC1A_HUMAN 137 FLFSLSQHiNWVRCAKFSPDGRLIVSASDDKTVKLWD 173 67899*******************************9 PP == domain 5 score: 34.8 bits; conditional E-value: 1.2e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c++++ H ++vt ++f+p+g+ +a++++D+tv++Wd sp|Q8NBT0|POC1A_HUMAN 178 ECVHSYCEHgGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215 8********777*************99999*******9 PP == domain 6 score: 24.0 bits; conditional E-value: 3e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +l+++ H v++l+f+p+g++l+++s D t++i sp|Q8NBT0|POC1A_HUMAN 221 LLQHYQLHsAAVNGLSFHPSGNYLITASSDSTLKI 255 68899999555**************9988*****9 PP == domain 7 score: 24.6 bits; conditional E-value: 1.9e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l+tl GH ++ t +afs+ g ++asG+ D v++W+ sp|Q8NBT0|POC1A_HUMAN 261 GRLLYTLHGHqGPATTVAFSRTGEYFASGGSDEQVMVWK 299 57899*****8889***************88*******6 PP >> sp|Q8TC44|POC1B_HUMAN POC1 centriolar protein homolog B OS=Homo sapiens GN=POC1B PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.5 0.0 2.3e-07 1.9e-05 6 38 .] 13 46 .. 8 46 .. 0.91 2 ! 35.9 0.0 5.2e-10 4.2e-08 7 37 .. 56 87 .. 52 87 .. 0.92 3 ! 33.7 0.0 2.7e-09 2.2e-07 5 38 .] 96 130 .. 92 130 .. 0.92 4 ! 36.3 0.2 4e-10 3.2e-08 5 38 .] 138 172 .. 134 172 .. 0.85 5 ! 21.3 0.3 2.2e-05 0.0018 13 38 .] 189 214 .. 176 214 .. 0.73 6 ! 32.7 0.2 5.5e-09 4.4e-07 2 36 .. 219 254 .. 218 256 .. 0.90 7 ! 25.0 0.0 1.5e-06 0.00012 2 37 .. 261 297 .. 260 298 .. 0.93 Alignments for each domain: == domain 1 score: 27.5 bits; conditional E-value: 2.3e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++GH +tsl+ sp+g+ la++s+D +++W+ sp|Q8TC44|POC1B_HUMAN 13 YFKGHkAAITSLDLSPNGKQLATASWDTFLMLWN 46 589**666*************************8 PP == domain 2 score: 35.9 bits; conditional E-value: 5.2e-10 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 + GH++ vts++fsp+g++las+s+D+tvr+W sp|Q8TC44|POC1B_HUMAN 56 YVGHKDvVTSVQFSPHGNLLASASRDRTVRLW 87 67**9966************************ PP == domain 3 score: 33.7 bits; conditional E-value: 2.7e-09 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++H +v+s++fs dg++la++s+D+++++W+ sp|Q8TC44|POC1B_HUMAN 96 SEFKAHtAPVRSVDFSADGQFLATASEDKSIKVWS 130 6799**888*************************5 PP == domain 4 score: 36.3 bits; conditional E-value: 4e-10 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l H +v++ +fspdg++++s+s+D+t++iWd sp|Q8TC44|POC1B_HUMAN 138 YSLYRHtHWVRCAKFSPDGRLIVSCSEDKTIKIWD 172 555556336*************************9 PP == domain 5 score: 21.3 bits; conditional E-value: 2.2e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + ++f+p+g+ +as++ D+tv++Wd sp|Q8TC44|POC1B_HUMAN 189 ANFVDFNPSGTCIASAGSDQTVKVWD 214 36688********97655*******9 PP == domain 6 score: 32.7 bits; conditional E-value: 5.5e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++l+++ H ++v++++f+p+g++l+++s Dgt++i sp|Q8TC44|POC1B_HUMAN 219 KLLQHYQVHsGGVNCISFHPSGNYLITASSDGTLKI 254 6899*****666**************9988*****9 PP == domain 7 score: 25.0 bits; conditional E-value: 1.5e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++tl GH ++v ++fs+ g ++asG+ D v +W sp|Q8TC44|POC1B_HUMAN 261 RLIYTLQGHtGPVFTVSFSKGGELFASGGADTQVLLW 297 6899*****888************************* PP >> sp|P43034|LIS1_HUMAN Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens GN=PAFAH1B1 PE=1 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 1.2e-05 0.00094 7 38 .] 104 136 .. 100 136 .. 0.94 2 ! 35.6 0.3 6.6e-10 5.4e-08 4 38 .] 143 178 .. 140 178 .. 0.93 3 ! 32.6 0.1 5.7e-09 4.6e-07 2 37 .. 183 219 .. 182 220 .. 0.93 4 ! 30.0 0.1 3.9e-08 3.1e-06 2 37 .. 225 261 .. 224 262 .. 0.96 5 ! 24.9 0.0 1.5e-06 0.00012 2 38 .] 267 324 .. 266 324 .. 0.92 6 ! 35.3 0.6 8e-10 6.5e-08 2 38 .] 329 366 .. 328 366 .. 0.96 7 ! 33.7 0.0 2.6e-09 2.1e-07 2 37 .. 371 407 .. 370 408 .. 0.93 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 1.2e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+GH s+vt + f+p + ++s+s+D t+++Wd sp|P43034|LIS1_HUMAN 104 LSGHrSPVTRVIFHPVFSVMVSASEDATIKVWD 136 89**999*************************9 PP == domain 2 score: 35.6 bits; conditional E-value: 6.6e-10 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH +sv +++f+++g++las+s D t+++Wd sp|P43034|LIS1_HUMAN 143 ERTLKGHtDSVQDISFDHSGKLLASCSADMTIKLWD 178 689****888*************************9 PP == domain 3 score: 32.6 bits; conditional E-value: 5.7e-09 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +c+rt GH++ v+s+a p+g+ ++s+s+D+t+++W sp|P43034|LIS1_HUMAN 183 ECIRTMHGHDHnVSSVAIMPNGDHIVSASRDKTIKMW 219 8********556************************* PP == domain 4 score: 30.0 bits; conditional E-value: 3.9e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++t+tGH +v+ ++ ++dg+++as+s D+tvr+W sp|P43034|LIS1_HUMAN 225 YCVKTFTGHrEWVRMVRPNQDGTLIASCSNDQTVRVW 261 69*******999************************* PP == domain 5 score: 24.9 bits; conditional E-value: 1.5e-06 EEEEEEESSSS.EEEEEEETTSSE....................EEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgaw....................lasGsdDgtvriWd 38 +c +l+ H + v ++++ p++++ l+sGs+D+t+++Wd sp|P43034|LIS1_HUMAN 267 ECKAELREHEHvVECISWAPESSYssiseatgsetkksgkpgpfLLSGSRDKTIKMWD 324 688999***8867*************999999999999999999899**********9 PP == domain 6 score: 35.3 bits; conditional E-value: 8e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 cl tl GH ++v+++ f++ g++++s+ dD+t+r+Wd sp|P43034|LIS1_HUMAN 329 MCLMTLVGHdNWVRGVLFHSGGKFILSCADDKTLRVWD 366 69*******999*************************9 PP == domain 7 score: 33.7 bits; conditional E-value: 2.6e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +c++tl +H +vtsl+f++ +++++Gs D+tv++W sp|P43034|LIS1_HUMAN 371 RCMKTLNAHeHFVTSLDFHKTAPYVVTGSVDQTVKVW 407 79*******666************************* PP >> sp|O14727-2|APAF_HUMAN Isoform 2 of Apoptotic protease-activating factor 1 OS=Homo sapiens GN=APAF1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0049 0.39 8 37 .. 601 631 .. 594 632 .. 0.86 2 ! 30.4 0.0 3e-08 2.4e-06 2 38 .] 637 674 .. 636 674 .. 0.91 3 ! 22.8 0.8 7.2e-06 0.00058 1 38 [] 678 718 .. 678 718 .. 0.82 4 ! 35.6 0.2 6.7e-10 5.4e-08 3 38 .] 724 760 .. 722 760 .. 0.91 5 ? 6.8 0.1 0.83 67 7 38 .] 825 857 .. 820 857 .. 0.87 6 ! 28.7 0.6 1e-07 8.1e-06 4 37 .. 864 898 .. 861 899 .. 0.92 7 ? 12.8 0.1 0.01 0.82 9 38 .] 990 1020 .. 981 1020 .. 0.89 8 ? 10.6 0.1 0.05 4.1 7 38 .] 1029 1060 .. 1024 1060 .. 0.85 9 ! 13.1 0.6 0.0081 0.66 4 38 .] 1067 1102 .. 1064 1102 .. 0.86 10 ! 31.3 0.1 1.5e-08 1.2e-06 3 38 .] 1108 1144 .. 1107 1144 .. 0.94 11 ! 16.5 0.1 0.00069 0.056 9 38 .] 1164 1192 .. 1156 1192 .. 0.86 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0049 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 + H + v++ +fs dg+ +as++ D+t+ ++ sp|O14727-2|APAF_HUMAN 601 RPHtDAVYHACFSEDGQRIASCGADKTLQVF 631 569566****************99***9886 PP == domain 2 score: 30.4 bits; conditional E-value: 3e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l ++++H + v ++afs d +++a++s D++v+iW+ sp|O14727-2|APAF_HUMAN 637 EKLLEIKAHeDEVLCCAFSTDDRFIATCSVDKKVKIWN 674 6677889**777*************************8 PP == domain 3 score: 22.8 bits; conditional E-value: 7.2e-06 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 g++++t++ H v+++ f +++ la+Gs D+ +++Wd sp|O14727-2|APAF_HUMAN 678 GELVHTYDEHsEQVNCCHFTNSSHHllLATGSSDCFLKLWD 718 6799******555****977777774468**99*******9 PP == domain 4 score: 35.6 bits; conditional E-value: 6.7e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c t GH +sv++++fspd ++las+s Dgt+++Wd sp|O14727-2|APAF_HUMAN 724 CRNTMFGHtNSVNHCRFSPDDKLLASCSADGTLKLWD 760 566666**999*************************9 PP == domain 5 score: 6.8 bits; conditional E-value: 0.83 EESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 tGH s + ++fsp +++ + + s v +W+ sp|O14727-2|APAF_HUMAN 825 HTGHhSTIQYCDFSPQNHLAVVAlS-QYCVELWN 857 3599888************888878.*******8 PP == domain 6 score: 28.7 bits; conditional E-value: 1e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + ++GH s+v+++ fspdg+ ++++sdD+t+r+W sp|O14727-2|APAF_HUMAN 864 VADCRGHlSWVHGVMFSPDGSSFLTSSDDQTIRLW 898 66789****************************** PP == domain 7 score: 12.8 bits; conditional E-value: 0.01 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H + v++++f d + l+s+sdD + +W+ sp|O14727-2|APAF_HUMAN 990 QHkKTVWHIQFTADEKTLISSSDDAEIQVWN 1020 59788*************************8 PP == domain 8 score: 10.6 bits; conditional E-value: 0.05 EESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 l+GH v +++ +++++l + s Dgtv++W+ sp|O14727-2|APAF_HUMAN 1029 LRGHqETVKDFRLLKNSRLL--SwSFDGTVKVWN 1060 79**766****999999998..5566*******8 PP == domain 9 score: 13.1 bits; conditional E-value: 0.0081 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + H + v s++ s+d + ++s s D+t +iW+ sp|O14727-2|APAF_HUMAN 1067 EKDFVCHqGTVLSCDISHDATKFSSTSADKTAKIWS 1102 5668899666*************98899*******5 PP == domain 10 score: 31.3 bits; conditional E-value: 1.5e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++l+GH ++v++ afs d+++la+G+d+g +riW+ sp|O14727-2|APAF_HUMAN 1108 PLHELRGHnGCVRCSAFSVDSTLLATGDDNGEIRIWN 1144 69******655*************************8 PP == domain 11 score: 16.5 bits; conditional E-value: 0.00069 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H ++vt+l+fspdg++l+s g ++ W+ sp|O14727-2|APAF_HUMAN 1164 THgGWVTDLCFSPDGKMLIS-A-GGYIKWWN 1192 58777*************95.6.88888887 PP >> sp|O14727|APAF_HUMAN Apoptotic protease-activating factor 1 OS=Homo sapiens GN=APAF1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.0 0.0049 0.4 8 37 .. 612 642 .. 605 643 .. 0.86 2 ! 30.3 0.0 3e-08 2.4e-06 2 38 .] 648 685 .. 647 685 .. 0.91 3 ! 22.8 0.8 7.3e-06 0.00059 1 38 [] 689 729 .. 689 729 .. 0.82 4 ! 35.6 0.2 6.7e-10 5.5e-08 3 38 .] 735 771 .. 733 771 .. 0.91 5 ? 6.8 0.1 0.84 68 7 38 .] 836 868 .. 831 868 .. 0.87 6 ! 28.7 0.6 1e-07 8.2e-06 4 37 .. 875 909 .. 872 910 .. 0.92 7 ? 12.8 0.1 0.01 0.83 9 38 .] 1001 1031 .. 992 1031 .. 0.89 8 ? 10.6 0.1 0.051 4.1 7 38 .] 1040 1071 .. 1035 1071 .. 0.85 9 ! 13.1 0.6 0.0082 0.66 4 38 .] 1078 1113 .. 1075 1113 .. 0.86 10 ! 31.3 0.1 1.5e-08 1.2e-06 3 38 .] 1119 1155 .. 1118 1155 .. 0.94 11 ! 16.5 0.1 0.0007 0.056 9 38 .] 1175 1203 .. 1167 1203 .. 0.86 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.0049 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 + H + v++ +fs dg+ +as++ D+t+ ++ sp|O14727|APAF_HUMAN 612 RPHtDAVYHACFSEDGQRIASCGADKTLQVF 642 569566****************99***9886 PP == domain 2 score: 30.3 bits; conditional E-value: 3e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l ++++H + v ++afs d +++a++s D++v+iW+ sp|O14727|APAF_HUMAN 648 EKLLEIKAHeDEVLCCAFSTDDRFIATCSVDKKVKIWN 685 6677889**777*************************8 PP == domain 3 score: 22.8 bits; conditional E-value: 7.3e-06 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 g++++t++ H v+++ f +++ la+Gs D+ +++Wd sp|O14727|APAF_HUMAN 689 GELVHTYDEHsEQVNCCHFTNSSHHllLATGSSDCFLKLWD 729 6799******555****977777774468**99*******9 PP == domain 4 score: 35.6 bits; conditional E-value: 6.7e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c t GH +sv++++fspd ++las+s Dgt+++Wd sp|O14727|APAF_HUMAN 735 CRNTMFGHtNSVNHCRFSPDDKLLASCSADGTLKLWD 771 566666**999*************************9 PP == domain 5 score: 6.8 bits; conditional E-value: 0.84 EESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 tGH s + ++fsp +++ + + s v +W+ sp|O14727|APAF_HUMAN 836 HTGHhSTIQYCDFSPQNHLAVVAlS-QYCVELWN 868 3599888************888878.*******8 PP == domain 6 score: 28.7 bits; conditional E-value: 1e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + ++GH s+v+++ fspdg+ ++++sdD+t+r+W sp|O14727|APAF_HUMAN 875 VADCRGHlSWVHGVMFSPDGSSFLTSSDDQTIRLW 909 66789****************************** PP == domain 7 score: 12.8 bits; conditional E-value: 0.01 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H + v++++f d + l+s+sdD + +W+ sp|O14727|APAF_HUMAN 1001 QHkKTVWHIQFTADEKTLISSSDDAEIQVWN 1031 59788*************************8 PP == domain 8 score: 10.6 bits; conditional E-value: 0.051 EESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 l+GH v +++ +++++l + s Dgtv++W+ sp|O14727|APAF_HUMAN 1040 LRGHqETVKDFRLLKNSRLL--SwSFDGTVKVWN 1071 79**766****999999998..5566*******8 PP == domain 9 score: 13.1 bits; conditional E-value: 0.0082 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + H + v s++ s+d + ++s s D+t +iW+ sp|O14727|APAF_HUMAN 1078 EKDFVCHqGTVLSCDISHDATKFSSTSADKTAKIWS 1113 5668899666*************98899*******5 PP == domain 10 score: 31.3 bits; conditional E-value: 1.5e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++l+GH ++v++ afs d+++la+G+d+g +riW+ sp|O14727|APAF_HUMAN 1119 PLHELRGHnGCVRCSAFSVDSTLLATGDDNGEIRIWN 1155 69******655*************************8 PP == domain 11 score: 16.5 bits; conditional E-value: 0.0007 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H ++vt+l+fspdg++l+s g ++ W+ sp|O14727|APAF_HUMAN 1175 THgGWVTDLCFSPDGKMLIS-A-GGYIKWWN 1203 58777*************95.6.88888887 PP >> sp|P61964|WDR5_HUMAN WD repeat-containing protein 5 OS=Homo sapiens GN=WDR5 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.2 0.0 4.3e-10 3.5e-08 5 37 .. 39 72 .. 35 72 .. 0.93 2 ! 36.0 0.6 4.8e-10 3.9e-08 3 38 .] 79 115 .. 77 115 .. 0.91 3 ! 39.8 0.2 3.1e-11 2.5e-09 1 38 [] 119 157 .. 119 157 .. 0.96 4 ! 36.8 0.3 2.8e-10 2.3e-08 1 38 [] 161 199 .. 161 199 .. 0.95 5 ! 25.2 0.0 1.3e-06 0.0001 1 38 [] 203 242 .. 203 242 .. 0.92 6 ! 25.1 0.1 1.3e-06 0.00011 1 38 [] 246 287 .. 246 287 .. 0.79 7 ! 16.5 0.0 0.00072 0.058 3 38 .] 293 331 .. 291 331 .. 0.79 Alignments for each domain: == domain 1 score: 36.2 bits; conditional E-value: 4.3e-10 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 tl GH + v+s++fsp+g wlas+s D+ ++iW sp|P61964|WDR5_HUMAN 39 FTLAGHtKAVSSVKFSPNGEWLASSSADKLIKIW 72 5788**999************************* PP == domain 2 score: 36.0 bits; conditional E-value: 4.8e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +t++GH +++++a+s+d+++l+s+sdD+t++iWd sp|P61964|WDR5_HUMAN 79 FEKTISGHkLGISDVAWSSDSNLLVSASDDKTLKIWD 115 568999**766*************************9 PP == domain 3 score: 39.8 bits; conditional E-value: 3.1e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+cl+tl+GH + v ++ f+p +++++sGs D +vriWd sp|P61964|WDR5_HUMAN 119 GKCLKTLKGHsNYVFCCNFNPQSNLIVSGSFDESVRIWD 157 79********777*************************9 PP == domain 4 score: 36.8 bits; conditional E-value: 2.8e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+cl+tl +H ++v+++ f++dg++++s+s+Dg +riWd sp|P61964|WDR5_HUMAN 161 GKCLKTLPAHsDPVSAVHFNRDGSLIVSSSYDGLCRIWD 199 79********666*************************9 PP == domain 5 score: 25.2 bits; conditional E-value: 1.3e-06 TEEEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 gqcl+tl ++ v+ ++fsp+g+++++++ D+t+++Wd sp|P61964|WDR5_HUMAN 203 GQCLKTLIDDdNPpVSFVKFSPNGKYILAATLDNTLKLWD 242 799***99776678**************9999*******9 PP == domain 6 score: 25.1 bits; conditional E-value: 1.3e-06 TEEEEEEESS.SS...EEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss...vtsla...fspdgawlasGsdDgtvriWd 38 g+cl+t+tGH + + g+w++sGs+D+ v+iW+ sp|P61964|WDR5_HUMAN 246 GKCLKTYTGHkNEkycI---FanfSVTGGKWIVSGSEDNLVYIWN 287 79********7666663...333355666***************8 PP == domain 7 score: 16.5 bits; conditional E-value: 0.00072 EEEEEESSSS..E.EEEEEETTSSEEEEEE..TTSEEEEEE CS WD40 3 clrtltGHss..v.tslafspdgawlasGs..dDgtvriWd 38 +++l GH++ + t++ +p + +as+ D+t+++W+ sp|P61964|WDR5_HUMAN 293 IVQKLQGHTDvvIsTAC--HPTENIIASAAleNDKTIKLWK 331 578899**886445666..*******9986445*******6 PP >> sp|O14727-3|APAF_HUMAN Isoform 3 of Apoptotic protease-activating factor 1 OS=Homo sapiens GN=APAF1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0047 0.38 8 37 .. 601 631 .. 594 632 .. 0.86 2 ! 30.4 0.0 2.8e-08 2.3e-06 2 38 .] 637 674 .. 636 674 .. 0.91 3 ! 22.9 0.8 6.9e-06 0.00056 1 38 [] 678 718 .. 678 718 .. 0.82 4 ! 35.6 0.2 6.4e-10 5.2e-08 3 38 .] 724 760 .. 722 760 .. 0.91 5 ? 7.5 0.0 0.48 39 13 38 .] 790 814 .. 781 814 .. 0.91 6 ! 28.7 0.6 9.6e-08 7.8e-06 4 37 .. 821 855 .. 818 856 .. 0.92 7 ! 12.9 0.1 0.0098 0.79 9 38 .] 947 977 .. 938 977 .. 0.89 8 ? 10.7 0.1 0.048 3.9 7 38 .] 986 1017 .. 981 1017 .. 0.85 9 ! 13.2 0.6 0.0078 0.63 4 38 .] 1024 1059 .. 1021 1059 .. 0.86 10 ! 31.3 0.1 1.5e-08 1.2e-06 3 38 .] 1065 1101 .. 1064 1101 .. 0.94 11 ! 16.6 0.1 0.00066 0.054 9 38 .] 1121 1149 .. 1113 1149 .. 0.86 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0047 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 + H + v++ +fs dg+ +as++ D+t+ ++ sp|O14727-3|APAF_HUMAN 601 RPHtDAVYHACFSEDGQRIASCGADKTLQVF 631 569566****************99***9886 PP == domain 2 score: 30.4 bits; conditional E-value: 2.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l ++++H + v ++afs d +++a++s D++v+iW+ sp|O14727-3|APAF_HUMAN 637 EKLLEIKAHeDEVLCCAFSTDDRFIATCSVDKKVKIWN 674 6677889**777*************************8 PP == domain 3 score: 22.9 bits; conditional E-value: 6.9e-06 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 g++++t++ H v+++ f +++ la+Gs D+ +++Wd sp|O14727-3|APAF_HUMAN 678 GELVHTYDEHsEQVNCCHFTNSSHHllLATGSSDCFLKLWD 718 6799******555****977777774468**99*******9 PP == domain 4 score: 35.6 bits; conditional E-value: 6.4e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c t GH +sv++++fspd ++las+s Dgt+++Wd sp|O14727-3|APAF_HUMAN 724 CRNTMFGHtNSVNHCRFSPDDKLLASCSADGTLKLWD 760 566666**999*************************9 PP == domain 5 score: 7.5 bits; conditional E-value: 0.48 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v ++++s dga ++ + ++++ +W+ sp|O14727-3|APAF_HUMAN 790 VKCCSWSADGARIMVAA-KNKIFLWN 814 68***********9999.*******8 PP == domain 6 score: 28.7 bits; conditional E-value: 9.6e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + ++GH s+v+++ fspdg+ ++++sdD+t+r+W sp|O14727-3|APAF_HUMAN 821 VADCRGHlSWVHGVMFSPDGSSFLTSSDDQTIRLW 855 66789****************************** PP == domain 7 score: 12.9 bits; conditional E-value: 0.0098 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H + v++++f d + l+s+sdD + +W+ sp|O14727-3|APAF_HUMAN 947 QHkKTVWHIQFTADEKTLISSSDDAEIQVWN 977 59788*************************8 PP == domain 8 score: 10.7 bits; conditional E-value: 0.048 EESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 l+GH v +++ +++++l + s Dgtv++W+ sp|O14727-3|APAF_HUMAN 986 LRGHqETVKDFRLLKNSRLL--SwSFDGTVKVWN 1017 79**766****999999998..5566*******8 PP == domain 9 score: 13.2 bits; conditional E-value: 0.0078 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + H + v s++ s+d + ++s s D+t +iW+ sp|O14727-3|APAF_HUMAN 1024 EKDFVCHqGTVLSCDISHDATKFSSTSADKTAKIWS 1059 5668899666*************98899*******5 PP == domain 10 score: 31.3 bits; conditional E-value: 1.5e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++l+GH ++v++ afs d+++la+G+d+g +riW+ sp|O14727-3|APAF_HUMAN 1065 PLHELRGHnGCVRCSAFSVDSTLLATGDDNGEIRIWN 1101 69******655*************************8 PP == domain 11 score: 16.6 bits; conditional E-value: 0.00066 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H ++vt+l+fspdg++l+s g ++ W+ sp|O14727-3|APAF_HUMAN 1121 THgGWVTDLCFSPDGKMLIS-A-GGYIKWWN 1149 58777*************95.6.88888887 PP >> sp|O14727-4|APAF_HUMAN Isoform 4 of Apoptotic protease-activating factor 1 OS=Homo sapiens GN=APAF1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0047 0.38 8 37 .. 612 642 .. 605 643 .. 0.86 2 ! 30.4 0.0 2.9e-08 2.3e-06 2 38 .] 648 685 .. 647 685 .. 0.91 3 ! 22.8 0.8 7e-06 0.00056 1 38 [] 689 729 .. 689 729 .. 0.82 4 ! 35.6 0.2 6.5e-10 5.3e-08 3 38 .] 735 771 .. 733 771 .. 0.91 5 ? 7.5 0.0 0.49 39 13 38 .] 801 825 .. 792 825 .. 0.91 6 ! 28.7 0.6 9.7e-08 7.8e-06 4 37 .. 832 866 .. 829 867 .. 0.92 7 ! 12.9 0.1 0.0099 0.8 9 38 .] 958 988 .. 949 988 .. 0.89 8 ? 10.7 0.1 0.049 4 7 38 .] 997 1028 .. 992 1028 .. 0.85 9 ! 13.2 0.6 0.0079 0.64 4 38 .] 1035 1070 .. 1032 1070 .. 0.86 10 ! 31.3 0.1 1.5e-08 1.2e-06 3 38 .] 1076 1112 .. 1075 1112 .. 0.94 11 ! 16.6 0.1 0.00067 0.054 9 38 .] 1132 1160 .. 1124 1160 .. 0.86 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0047 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 + H + v++ +fs dg+ +as++ D+t+ ++ sp|O14727-4|APAF_HUMAN 612 RPHtDAVYHACFSEDGQRIASCGADKTLQVF 642 569566****************99***9886 PP == domain 2 score: 30.4 bits; conditional E-value: 2.9e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l ++++H + v ++afs d +++a++s D++v+iW+ sp|O14727-4|APAF_HUMAN 648 EKLLEIKAHeDEVLCCAFSTDDRFIATCSVDKKVKIWN 685 6677889**777*************************8 PP == domain 3 score: 22.8 bits; conditional E-value: 7e-06 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 g++++t++ H v+++ f +++ la+Gs D+ +++Wd sp|O14727-4|APAF_HUMAN 689 GELVHTYDEHsEQVNCCHFTNSSHHllLATGSSDCFLKLWD 729 6799******555****977777774468**99*******9 PP == domain 4 score: 35.6 bits; conditional E-value: 6.5e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c t GH +sv++++fspd ++las+s Dgt+++Wd sp|O14727-4|APAF_HUMAN 735 CRNTMFGHtNSVNHCRFSPDDKLLASCSADGTLKLWD 771 566666**999*************************9 PP == domain 5 score: 7.5 bits; conditional E-value: 0.49 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v ++++s dga ++ + ++++ +W+ sp|O14727-4|APAF_HUMAN 801 VKCCSWSADGARIMVAA-KNKIFLWN 825 68***********9999.*******8 PP == domain 6 score: 28.7 bits; conditional E-value: 9.7e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + ++GH s+v+++ fspdg+ ++++sdD+t+r+W sp|O14727-4|APAF_HUMAN 832 VADCRGHlSWVHGVMFSPDGSSFLTSSDDQTIRLW 866 66789****************************** PP == domain 7 score: 12.9 bits; conditional E-value: 0.0099 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H + v++++f d + l+s+sdD + +W+ sp|O14727-4|APAF_HUMAN 958 QHkKTVWHIQFTADEKTLISSSDDAEIQVWN 988 59788*************************8 PP == domain 8 score: 10.7 bits; conditional E-value: 0.049 EESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 l+GH v +++ +++++l + s Dgtv++W+ sp|O14727-4|APAF_HUMAN 997 LRGHqETVKDFRLLKNSRLL--SwSFDGTVKVWN 1028 79**766****999999998..5566*******8 PP == domain 9 score: 13.2 bits; conditional E-value: 0.0079 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + H + v s++ s+d + ++s s D+t +iW+ sp|O14727-4|APAF_HUMAN 1035 EKDFVCHqGTVLSCDISHDATKFSSTSADKTAKIWS 1070 5668899666*************98899*******5 PP == domain 10 score: 31.3 bits; conditional E-value: 1.5e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++l+GH ++v++ afs d+++la+G+d+g +riW+ sp|O14727-4|APAF_HUMAN 1076 PLHELRGHnGCVRCSAFSVDSTLLATGDDNGEIRIWN 1112 69******655*************************8 PP == domain 11 score: 16.6 bits; conditional E-value: 0.00067 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H ++vt+l+fspdg++l+s g ++ W+ sp|O14727-4|APAF_HUMAN 1132 THgGWVTDLCFSPDGKMLIS-A-GGYIKWWN 1160 58777*************95.6.88888887 PP >> sp|Q6ZMW3-2|EMAL6_HUMAN Isoform 2 of Echinoderm microtubule-associated protein-like 6 OS=Homo sapiens GN=EML6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.0 0.00058 0.047 4 38 .] 54 91 .. 51 91 .. 0.88 2 ! 16.4 0.3 0.00078 0.064 7 38 .] 104 136 .. 96 136 .. 0.80 3 ? 8.0 0.2 0.35 29 2 37 .. 141 177 .. 140 178 .. 0.82 4 ? 11.0 0.0 0.038 3 9 38 .] 235 263 .. 226 263 .. 0.66 5 ! 24.2 0.0 2.7e-06 0.00021 2 38 .] 315 353 .. 314 353 .. 0.89 6 ? 7.3 0.0 0.56 45 13 34 .. 369 390 .. 358 392 .. 0.87 7 ? 10.4 0.0 0.06 4.8 10 32 .. 403 430 .. 397 430 .. 0.85 8 ! 21.7 1.9 1.7e-05 0.0013 3 37 .. 555 591 .. 553 592 .. 0.87 9 ! 15.1 0.1 0.0019 0.15 4 38 .] 720 757 .. 715 757 .. 0.89 10 ? 9.5 0.3 0.12 9.5 2 32 .. 762 795 .. 761 802 .. 0.75 11 ? 11.2 0.0 0.034 2.8 4 38 .] 896 929 .. 894 929 .. 0.76 12 ! 13.0 0.0 0.009 0.73 8 37 .. 994 1025 .. 988 1026 .. 0.87 13 ? 5.5 0.1 2.1 1.7e+02 14 35 .. 1044 1065 .. 1043 1068 .. 0.87 14 ? 3.5 0.1 9.2 7.4e+02 3 31 .. 1183 1213 .. 1181 1216 .. 0.79 15 ! 13.4 0.3 0.0067 0.54 5 37 .. 1232 1266 .. 1229 1267 .. 0.81 16 ? 4.3 0.1 5 4e+02 9 37 .. 1460 1491 .. 1450 1492 .. 0.77 17 ! 24.0 0.2 3e-06 0.00024 8 38 .] 1683 1715 .. 1678 1715 .. 0.90 18 ? 4.0 0.0 6.4 5.2e+02 9 32 .. 1728 1750 .. 1720 1754 .. 0.81 19 ? 6.4 0.0 1.1 87 13 34 .. 1773 1794 .. 1759 1798 .. 0.85 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 0.00058 EEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++ + GH +++ sla +pd++++a+G ++ + + iWd sp|Q6ZMW3-2|EMAL6_HUMAN 54 QKFFLGHnDDIISLALHPDKTLVATGqvGKEPYICIWD 91 56678**66688**************999********9 PP == domain 2 score: 16.4 bits; conditional E-value: 0.00078 EESSSSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 7 ltGHssvtslafspdgawlasG..sdDgtvriWd 38 +H +v +laf++dg+ las + ++tv iWd sp|Q6ZMW3-2|EMAL6_HUMAN 104 VHTH-GVACLAFDSDGQRLASVglDAKNTVCIWD 136 4566.8*************9752546*******9 PP == domain 3 score: 8.0 bits; conditional E-value: 0.35 EEEEEEESSSS.EEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgaw.lasGsdDgtvriW 37 ++l + tGHs+ + +++++p+++ ++s++ +++++W sp|Q6ZMW3-2|EMAL6_HUMAN 141 KLLASATGHSDrIFDISWDPYQPNrVVSCG-VKHIKFW 177 6777889**556************988999.7777777 PP == domain 4 score: 11.0 bits; conditional E-value: 0.038 SS.SSEEEEEEETTSSE.....EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw.....lasGsdDgtvriWd 38 +H ++ s+ + +a+G++Dg +r+Wd sp|Q6ZMW3-2|EMAL6_HUMAN 235 AHsAGIFSM-------YaceegFATGGRDGCIRLWD 263 454446666.......333455799**********9 PP == domain 5 score: 24.2 bits; conditional E-value: 2.7e-06 EEEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 +++ +l GH + ++la +p +++ ++GsdD++vr+W+ sp|Q6ZMW3-2|EMAL6_HUMAN 315 KPMLILQGHcEGeLWALALHPKKPLAVTGSDDRSVRLWS 353 578899***7336*************************5 PP == domain 6 score: 7.3 bits; conditional E-value: 0.56 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 v+s+afspdg+ la G++Dg+ sp|Q6ZMW3-2|EMAL6_HUMAN 369 VRSVAFSPDGSQLALGMKDGSF 390 99**********9889999985 PP == domain 7 score: 10.4 bits; conditional E-value: 0.06 S.SS....EEEEEEETTSSEEEEEETTS CS WD40 10 H.ss....vtslafspdgawlasGsdDg 32 H ++ ++ ++fspdg++la Gs Dg sp|Q6ZMW3-2|EMAL6_HUMAN 403 HiKDrkevIHEMKFSPDGSYLAVGSNDG 430 666667767999*************997 PP == domain 8 score: 21.7 bits; conditional E-value: 1.7e-05 EEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla.sGsdDgtvriW 37 + r++ GH +vt +++s+d +w++ +G+ D++v W sp|Q6ZMW3-2|EMAL6_HUMAN 555 KFRKYVGHsAHVTNVRWSHDFQWVLsTGGADHSVFQW 591 578999**777************7648999******9 PP == domain 9 score: 15.1 bits; conditional E-value: 0.0019 EEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 +r + GH +++ sl +p ++++a+G ++D +++Wd sp|Q6ZMW3-2|EMAL6_HUMAN 720 QRLYLGHdDDILSLTIHPVKDYVATGqvGRDAAIHVWD 757 45577**888****************9999*******9 PP == domain 10 score: 9.5 bits; conditional E-value: 0.12 EEEEEEESS.SS.EEEEEEETTSSEEEEEE.TTS CS WD40 2 qclrtltGH.ss.vtslafspdgawlasGs.dDg 32 +cl l+G+ + v++l+fs dg+ l+s + dD sp|Q6ZMW3-2|EMAL6_HUMAN 762 KCLSLLKGQhQRgVCALDFSADGKCLVSVGlDDF 795 6888899885336*************97553554 PP == domain 11 score: 11.2 bits; conditional E-value: 0.034 EEEEESS.SSE...EEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssv...tslafspdgawlasGsdDgtvriWd 38 l+t ++H ++v ++l d+ ++ +G++Dg v +Wd sp|Q6ZMW3-2|EMAL6_HUMAN 896 LKTVKAHdGPVfamYAL----DKGFV-TGGKDGIVELWD 929 78999997778333555....66665.8**********9 PP == domain 12 score: 13.0 bits; conditional E-value: 0.009 ESS..SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriW 37 GH + v++la +p + a+ sdD+t+riW sp|Q6ZMW3-2|EMAL6_HUMAN 994 QGHmeGEVWGLAAHPLLPICATVSDDKTLRIW 1025 6999555************9999********* PP == domain 13 score: 5.5 bits; conditional E-value: 2.1 EEEEEETTSSEEEEEETTSEEE CS WD40 14 tslafspdgawlasGsdDgtvr 35 +++afspdg+ la G Dg+ sp|Q6ZMW3-2|EMAL6_HUMAN 1044 RCCAFSPDGKALAVGLNDGSFL 1065 59************97799865 PP == domain 14 score: 3.5 bits; conditional E-value: 9.2 EEEEEESSSSEEEEE...EETTSSEEEEEETT CS WD40 3 clrtltGHssvtsla...fspdgawlasGsdD 31 c +++ +Hs++t++ +d ++la+G+ D sp|Q6ZMW3-2|EMAL6_HUMAN 1183 CEGIWPAHSDITDVNaasLTKDCSLLATGD-D 1213 778899**8877776666999999999987.6 PP == domain 15 score: 13.4 bits; conditional E-value: 0.0067 EEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawla.sGsdDgtvriW 37 +++ GH +vt +++ ++ + l+ G+ D ++iW sp|Q6ZMW3-2|EMAL6_HUMAN 1232 KKYVGHsAHVTNVRWLHNDSVLLtVGGADTALMIW 1266 5789**777****977777776526899******* PP == domain 16 score: 4.3 bits; conditional E-value: 5 SS.SSEEEEEEETTSSEEEEEET..TSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsd..DgtvriW 37 H ++v+ + fs g++l+s + +t+ +W sp|Q6ZMW3-2|EMAL6_HUMAN 1460 FHsKGVNYINFSATGKLLVSVGVdpEHTITVW 1491 69888*************98775478888888 PP == domain 17 score: 24.0 bits; conditional E-value: 3e-06 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 +GH + +++la++p++++++s+s Dgt riWd sp|Q6ZMW3-2|EMAL6_HUMAN 1683 DGHmeGEIWGLATHPSKDLFISASNDGTARIWD 1715 69*9555*************************9 PP == domain 18 score: 4.0 bits; conditional E-value: 6.4 SSSSEEEEEEETTSSEEEEEETTS CS WD40 9 GHssvtslafspdgawlasGsdDg 32 GH ++ a+spdg ++a G+++g sp|Q6ZMW3-2|EMAL6_HUMAN 1728 GH-AARCAAYSPDGEMVAIGMKNG 1750 78.5699***********999776 PP == domain 19 score: 6.4 bits; conditional E-value: 1.1 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 + +++ spd+++la Gs +tv sp|Q6ZMW3-2|EMAL6_HUMAN 1773 IQDIRISPDNRFLAVGSSEHTV 1794 89999***********889988 PP >> sp|Q86VZ2|WDR5B_HUMAN WD repeat-containing protein 5B OS=Homo sapiens GN=WDR5B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.9 0.1 9.9e-09 8e-07 6 37 .. 36 68 .. 32 68 .. 0.91 2 ! 32.1 0.2 8.1e-09 6.5e-07 2 38 .] 74 111 .. 73 111 .. 0.89 3 ! 36.7 0.1 2.8e-10 2.3e-08 1 37 [. 115 152 .. 115 153 .. 0.95 4 ! 35.8 1.0 5.8e-10 4.7e-08 1 38 [] 157 195 .. 157 195 .. 0.95 5 ! 25.3 0.0 1.2e-06 9.4e-05 1 38 [] 199 238 .. 199 238 .. 0.92 6 ! 24.5 0.1 2e-06 0.00016 1 38 [] 242 283 .. 242 283 .. 0.79 7 ! 16.9 0.0 0.00053 0.043 3 37 .. 289 326 .. 287 327 .. 0.84 Alignments for each domain: == domain 1 score: 31.9 bits; conditional E-value: 9.9e-09 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 tl GH v+s++fsp+g wlas+s D+ + iW sp|Q86VZ2|WDR5B_HUMAN 36 TLVGHtEAVSSVKFSPNGEWLASSSADRLIIIW 68 678**777************************* PP == domain 2 score: 32.1 bits; conditional E-value: 8.1e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +tl GH ++++a+s+d++ l+s+sdD+t+++Wd sp|Q86VZ2|WDR5B_HUMAN 74 KYEKTLYGHnLEISDVAWSSDSSRLVSASDDKTLKLWD 111 5668999**444*************************9 PP == domain 3 score: 36.7 bits; conditional E-value: 2.8e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+cl+tl+GH + v ++ f+p +++++sGs D tv+iW sp|Q86VZ2|WDR5B_HUMAN 115 GKCLKTLKGHsNYVFCCNFNPPSNLIISGSFDETVKIW 152 79********777************************* PP == domain 4 score: 35.8 bits; conditional E-value: 5.8e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+cl+tl++H ++v+++ f+ +g++++sGs+Dg +riWd sp|Q86VZ2|WDR5B_HUMAN 157 GKCLKTLSAHsDPVSAVHFNCSGSLIVSGSYDGLCRIWD 195 79********666*************************9 PP == domain 5 score: 25.3 bits; conditional E-value: 1.2e-06 TEEEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 gqcl+tl ++ v+ ++fsp+g+++++++ D+t+++Wd sp|Q86VZ2|WDR5B_HUMAN 199 GQCLKTLVDDdNPpVSFVKFSPNGKYILTATLDNTLKLWD 238 79999998776668****************99*******9 PP == domain 6 score: 24.5 bits; conditional E-value: 2e-06 TEEEEEEESS.SS...EEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss...vtsla...fspdgawlasGsdDgtvriWd 38 g+cl+t+tGH + + g+w++sGs+D+ v+iW+ sp|Q86VZ2|WDR5B_HUMAN 242 GRCLKTYTGHkNEkycI---FanfSVTGGKWIVSGSEDNLVYIWN 283 68********7666663...333355666***************8 PP == domain 7 score: 16.9 bits; conditional E-value: 0.00053 EEEEEESSSS.EEEEEEETTSSEEEEEE..TTSEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGs..dDgtvriW 37 +++l GH++ v s a +p +++as+ D+t+++W sp|Q86VZ2|WDR5B_HUMAN 289 IVQKLQGHTDvVISAACHPTENLIASAAleNDKTIKLW 326 57889***88657999********9986445******* PP >> sp|Q15542|TAF5_HUMAN Transcription initiation factor TFIID subunit 5 OS=Homo sapiens GN=TAF5 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 0.1 0.006 0.49 11 38 .] 471 498 .. 461 498 .. 0.81 2 ! 34.0 0.0 2e-09 1.6e-07 3 38 .] 535 571 .. 533 571 .. 0.92 3 ! 23.1 0.2 5.9e-06 0.00048 2 37 .. 576 612 .. 575 612 .. 0.91 4 ! 41.5 0.0 8.9e-12 7.2e-10 2 38 .] 618 655 .. 617 655 .. 0.97 5 ! 41.7 0.1 7.8e-12 6.3e-10 1 38 [] 659 697 .. 659 697 .. 0.95 6 ! 37.8 0.0 1.3e-10 1.1e-08 4 38 .] 704 739 .. 701 739 .. 0.92 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 0.006 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++ t++++ +d++++a G D tvr+W+ sp|Q15542|TAF5_HUMAN 471 QGLTAVDVTDDSSLIAGGFADSTVRVWS 498 56899*********986668*******5 PP == domain 2 score: 34.0 bits; conditional E-value: 2e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++l GH ++v++ +fspd ++l+s+s+Dgtvr+W+ sp|Q15542|TAF5_HUMAN 535 ELKILYGHsGPVYGASFSPDRNYLLSSSEDGTVRLWS 571 689999**777*************************5 PP == domain 3 score: 23.1 bits; conditional E-value: 5.9e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +cl ++GH+ v++ +fsp+g +++sG+ D+ r+W sp|Q15542|TAF5_HUMAN 576 TCLVGYKGHNYpVWDTQFSPYGYYFVSGGHDRVARLW 612 588889***556****************99******* PP == domain 4 score: 41.5 bits; conditional E-value: 8.9e-12 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+lr++ GH +v++ +f+p+++++a+Gs D+tvr+Wd sp|Q15542|TAF5_HUMAN 618 QPLRIFAGHlADVNCTRFHPNSNYVATGSADRTVRLWD 655 89***********************************9 PP == domain 5 score: 41.7 bits; conditional E-value: 7.8e-12 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c+r++tGH ++++sl fsp+g++la+G Dg v +Wd sp|Q15542|TAF5_HUMAN 659 GNCVRIFTGHkGPIHSLTFSPNGRFLATGATDGRVLLWD 697 79********777****************88*******9 PP == domain 6 score: 37.8 bits; conditional E-value: 1.3e-10 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++l+GH + v+sl+fs+dg lasGs+D+tvr+Wd sp|Q15542|TAF5_HUMAN 704 VGELKGHtDTVCSLRFSRDGEILASGSMDNTVRLWD 739 5789***666*************************9 PP >> sp|Q9UNX4|WDR3_HUMAN WD repeat-containing protein 3 OS=Homo sapiens GN=WDR3 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.0 2.7e-05 0.0022 11 37 .. 66 92 .. 55 93 .. 0.83 2 ! 18.2 0.1 0.0002 0.016 6 38 .] 102 135 .. 97 135 .. 0.90 3 ! 16.0 0.0 0.0011 0.085 4 38 .] 142 177 .. 139 177 .. 0.89 4 ! 14.7 0.0 0.0026 0.21 2 38 .] 182 219 .. 181 219 .. 0.84 5 ! 13.2 0.1 0.0076 0.61 6 38 .] 410 442 .. 402 442 .. 0.89 6 ! 20.9 0.1 2.9e-05 0.0023 2 38 .] 487 524 .. 486 524 .. 0.91 7 ? 11.6 0.0 0.025 2 12 37 .. 551 576 .. 541 576 .. 0.87 8 ! 25.9 0.1 7.6e-07 6.2e-05 6 37 .. 586 618 .. 581 618 .. 0.90 9 ! 14.2 0.3 0.0038 0.31 2 38 .] 624 661 .. 623 661 .. 0.91 10 ! 36.6 0.2 3.2e-10 2.6e-08 2 37 .. 666 702 .. 665 703 .. 0.92 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 2.7e-05 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 + vt+l+ spdg la G +Dg++ri+ sp|Q9UNX4|WDR3_HUMAN 66 QEVTCLCPSPDGLHLAVGYEDGSIRIF 92 34************************7 PP == domain 2 score: 18.2 bits; conditional E-value: 0.0002 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t+ GH +t l++++ g lasGs+D + +Wd sp|Q9UNX4|WDR3_HUMAN 102 TFNGHkAAITTLKYDQLGGRLASGSKDTDIIVWD 135 799**666****99999999*************9 PP == domain 3 score: 16.0 bits; conditional E-value: 0.0011 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 l+ l+GH++ +t f +++++l+++++D v+ Wd sp|Q9UNX4|WDR3_HUMAN 142 LYRLKGHKDaITQALFLREKNLLVTSGKDTMVKWWD 177 66799**555*9999********************9 PP == domain 4 score: 14.7 bits; conditional E-value: 0.0026 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +t GH + v++l ++ + l++G D +r+Wd sp|Q9UNX4|WDR3_HUMAN 182 HCFKTMVGHrTEVWGLVLLSEEKRLITGASDSELRVWD 219 5889999**999****97777777789955*******9 PP == domain 5 score: 13.2 bits; conditional E-value: 0.0076 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t+ GH s+v+ l+fs+d+ ++s+ +++iW+ sp|Q9UNX4|WDR3_HUMAN 410 TIGGHrSDVRTLSFSSDNIAVLSAA-ADSIKIWN 442 467*******************999.*******8 PP == domain 6 score: 20.9 bits; conditional E-value: 2.9e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l t+++H + +s++ spd++ +++G+ D++v++Wd sp|Q9UNX4|WDR3_HUMAN 487 NLLETIDAHdGALWSMSLSPDQRGFVTGGADKSVKFWD 524 6788999**666*************************9 PP == domain 7 score: 11.6 bits; conditional E-value: 0.025 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +v ++++sp++++la + D+tv+i+ sp|Q9UNX4|WDR3_HUMAN 551 DVLCVSYSPNQKLLAVSLLDCTVKIF 576 599***********98877*****96 PP == domain 8 score: 25.9 bits; conditional E-value: 7.6e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l GH +v +++ s+dga++a+Gs D++v+iW sp|Q9UNX4|WDR3_HUMAN 586 SLYGHkLPVICMDISHDGALIATGSADRNVKIW 618 678**77788*********************** PP == domain 9 score: 14.2 bits; conditional E-value: 0.0038 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c ++l +H +sv l+f p +++++++++D++++ Wd sp|Q9UNX4|WDR3_HUMAN 624 DCHKSLFAHdDSVMYLQFVPKSHLFFTAGKDHKIKQWD 661 67788889*777*************************9 PP == domain 10 score: 36.6 bits; conditional E-value: 3.2e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++tl+GH + +++la+sp+g++++s+s D+++r+W sp|Q9UNX4|WDR3_HUMAN 666 EHIQTLEGHhQEIWCLAVSPSGDYVVSSSHDKSLRLW 702 5789*****888**************9999******* PP >> sp|Q8NBT0-3|POC1A_HUMAN Isoform 3 of POC1 centriolar protein homolog A OS=Homo sapiens GN=POC1A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.1 0.1 2.8e-12 2.2e-10 6 37 .. 18 50 .. 13 51 .. 0.91 2 ! 26.4 0.5 5.2e-07 4.2e-05 5 37 .. 59 92 .. 56 92 .. 0.93 3 ! 39.1 0.2 5.1e-11 4.1e-09 3 38 .] 99 135 .. 97 135 .. 0.94 4 ! 34.9 0.2 1e-09 8.5e-08 2 38 .] 140 177 .. 139 177 .. 0.94 5 ! 24.2 0.1 2.6e-06 0.00021 3 36 .. 183 217 .. 181 219 .. 0.87 6 ! 24.8 0.0 1.7e-06 0.00014 1 38 [] 223 261 .. 223 261 .. 0.92 Alignments for each domain: == domain 1 score: 43.1 bits; conditional E-value: 2.8e-12 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriW 37 +tGH++ vt++ fsp+g++lasGs+D+tvriW sp|Q8NBT0-3|POC1A_HUMAN 18 RFTGHKDaVTCVNFSPSGHLLASGSRDKTVRIW 50 589**555************************* PP == domain 2 score: 26.4 bits; conditional E-value: 5.2e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++++H v+s+ f++dg+ ++++sdD+tv++W sp|Q8NBT0-3|POC1A_HUMAN 59 TVFRAHtATVRSVHFCSDGQSFVTASDDKTVKVW 92 579***777************************* PP == domain 3 score: 39.1 bits; conditional E-value: 5.1e-11 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l+ H ++v++ +fspdg++++s+sdD+tv++Wd sp|Q8NBT0-3|POC1A_HUMAN 99 FLFSLSQHiNWVRCAKFSPDGRLIVSASDDKTVKLWD 135 67899*******************************9 PP == domain 4 score: 34.9 bits; conditional E-value: 1e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c++++ H ++vt ++f+p+g+ +a++++D+tv++Wd sp|Q8NBT0-3|POC1A_HUMAN 140 ECVHSYCEHgGFVTYVDFHPSGTCIAAAGMDNTVKVWD 177 8********777*************99999*******9 PP == domain 5 score: 24.2 bits; conditional E-value: 2.6e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +l+++ H v++l+f+p+g++l+++s D t++i sp|Q8NBT0-3|POC1A_HUMAN 183 LLQHYQLHsAAVNGLSFHPSGNYLITASSDSTLKI 217 68899999555**************9988*****9 PP == domain 6 score: 24.8 bits; conditional E-value: 1.7e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l+tl GH ++ t +afs+ g ++asG+ D v++W+ sp|Q8NBT0-3|POC1A_HUMAN 223 GRLLYTLHGHqGPATTVAFSRTGEYFASGGSDEQVMVWK 261 57899*****8889***************88*******6 PP >> sp|Q8TC44-2|POC1B_HUMAN Isoform 2 of POC1 centriolar protein homolog B OS=Homo sapiens GN=POC1B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.1 0.0 4.6e-10 3.8e-08 7 37 .. 14 45 .. 10 45 .. 0.92 2 ! 33.8 0.0 2.4e-09 1.9e-07 5 38 .] 54 88 .. 50 88 .. 0.92 3 ! 36.4 0.2 3.5e-10 2.9e-08 5 38 .] 96 130 .. 92 130 .. 0.85 4 ! 21.4 0.3 2e-05 0.0016 13 38 .] 147 172 .. 134 172 .. 0.73 5 ! 32.8 0.2 4.8e-09 3.9e-07 2 36 .. 177 212 .. 176 214 .. 0.90 6 ! 25.1 0.0 1.3e-06 0.00011 2 37 .. 219 255 .. 218 256 .. 0.93 Alignments for each domain: == domain 1 score: 36.1 bits; conditional E-value: 4.6e-10 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 + GH++ vts++fsp+g++las+s+D+tvr+W sp|Q8TC44-2|POC1B_HUMAN 14 YVGHKDvVTSVQFSPHGNLLASASRDRTVRLW 45 67**9966************************ PP == domain 2 score: 33.8 bits; conditional E-value: 2.4e-09 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++H +v+s++fs dg++la++s+D+++++W+ sp|Q8TC44-2|POC1B_HUMAN 54 SEFKAHtAPVRSVDFSADGQFLATASEDKSIKVWS 88 6799**888*************************5 PP == domain 3 score: 36.4 bits; conditional E-value: 3.5e-10 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l H +v++ +fspdg++++s+s+D+t++iWd sp|Q8TC44-2|POC1B_HUMAN 96 YSLYRHtHWVRCAKFSPDGRLIVSCSEDKTIKIWD 130 555556336*************************9 PP == domain 4 score: 21.4 bits; conditional E-value: 2e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + ++f+p+g+ +as++ D+tv++Wd sp|Q8TC44-2|POC1B_HUMAN 147 ANFVDFNPSGTCIASAGSDQTVKVWD 172 36688********97655*******9 PP == domain 5 score: 32.8 bits; conditional E-value: 4.8e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++l+++ H ++v++++f+p+g++l+++s Dgt++i sp|Q8TC44-2|POC1B_HUMAN 177 KLLQHYQVHsGGVNCISFHPSGNYLITASSDGTLKI 212 6899*****666**************9988*****9 PP == domain 6 score: 25.1 bits; conditional E-value: 1.3e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++tl GH ++v ++fs+ g ++asG+ D v +W sp|Q8TC44-2|POC1B_HUMAN 219 RLIYTLQGHtGPVFTVSFSKGGELFASGGADTQVLLW 255 6899*****888************************* PP >> sp|Q12788|TBL3_HUMAN Transducin beta-like protein 3 OS=Homo sapiens GN=TBL3 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 6.8 5.5e+02 5 29 .. 59 85 .. 55 105 .. 0.79 2 ! 21.5 0.0 1.9e-05 0.0015 10 38 .] 108 137 .. 98 137 .. 0.91 3 ? 10.9 0.2 0.042 3.4 5 38 .] 140 181 .. 138 181 .. 0.67 4 ! 31.3 0.2 1.5e-08 1.2e-06 2 38 .] 186 223 .. 185 223 .. 0.96 5 ? 6.0 0.0 1.4 1.2e+02 24 37 .. 261 274 .. 248 275 .. 0.76 6 ! 13.5 0.4 0.0061 0.49 5 37 .. 370 403 .. 366 404 .. 0.77 7 ! 14.9 0.6 0.0023 0.19 3 37 .. 413 449 .. 412 449 .. 0.65 8 ! 25.1 0.0 1.4e-06 0.00011 4 37 .. 472 506 .. 469 506 .. 0.92 9 ! 29.7 0.1 4.8e-08 3.9e-06 2 37 .. 512 548 .. 511 548 .. 0.95 10 ! 24.4 0.1 2.2e-06 0.00018 2 37 .. 554 590 .. 553 591 .. 0.82 11 ! 13.2 0.5 0.0077 0.62 2 38 .] 596 633 .. 595 633 .. 0.89 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.8 EEEESS..SSEEEEEEETTSSEEEEEE CS WD40 5 rtltGH..ssvtslafspdgawlasGs 29 r+l+ ++t+++ spd+ l+++s sp|Q12788|TBL3_HUMAN 59 RSLEQEdqEDITAFDLSPDNEVLVTAS 85 5555333245**************988 PP == domain 2 score: 21.5 bits; conditional E-value: 1.9e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +v +af+p +++la+G+ Dg vr+Wd sp|Q12788|TBL3_HUMAN 108 HtAPVATMAFDPTSTLLATGGCDGAVRVWD 137 656689999***********88*******9 PP == domain 3 score: 10.9 bits; conditional E-value: 0.042 EEEESS.SS.....EEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 5 rtltGH.ss.....vtslafspdgawla..sGsdDgtvriWd 38 r++ +H + v+ +af+pd + l+ s+ D +r+W+ sp|Q12788|TBL3_HUMAN 140 RHYGTHhFRgspgvVHLVAFHPDPTRLLlfSSATDAAIRVWS 181 5565554113357567777*******64447666*******5 PP == domain 4 score: 31.3 bits; conditional E-value: 1.5e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl +lt+H s vtslafs dg+ ++s+++D+ + iWd sp|Q12788|TBL3_HUMAN 186 SCLAVLTAHySAVTSLAFSADGHTMLSSGRDKICIIWD 223 79*******999*************99999*******9 PP == domain 5 score: 6.0 bits; conditional E-value: 1.4 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 ++++++d gt+r+W sp|Q12788|TBL3_HUMAN 261 YFLTAGDQGTLRVW 274 4456777******* PP == domain 6 score: 13.5 bits; conditional E-value: 0.0061 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriW 37 ++l GH++ v +l++ + g ++as+ +D++vriW sp|Q12788|TBL3_HUMAN 370 QILHGHTDiVLALDVFRKGWLFASCAKDQSVRIW 403 5788**66479996555544478999******** PP == domain 7 score: 14.9 bits; conditional E-value: 0.0023 EEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 c+ +GH sv ++ ++l++Gs D+tv++W sp|Q12788|TBL3_HUMAN 413 CVAQGSGHtHSVGTVCcSRLKESFLVTGSQDCTVKLW 449 56666899545633331333444489*********** PP == domain 8 score: 25.1 bits; conditional E-value: 1.4e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++t + H ++++s+a p+ ++la+Gs D+t ++W sp|Q12788|TBL3_HUMAN 472 QTTQRCHdKDINSVAIAPNDKLLATGSQDRTAKLW 506 667789*999************************* PP == domain 9 score: 29.7 bits; conditional E-value: 4.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 q+l++++GH + ++++fsp + la++s Dgt+++W sp|Q12788|TBL3_HUMAN 512 QLLGVFSGHrRGLWCVQFSPMDQVLATASADGTIKLW 548 7899*****888************************* PP == domain 10 score: 24.4 bits; conditional E-value: 2.2e-06 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 +cl+t++GH sv +a +s+ ++l+sGs Dg v++W sp|Q12788|TBL3_HUMAN 554 SCLKTFEGHdASVLKVAfVSRGTQLLSSGS-DGLVKLW 590 7********888*****5555555566788.******* PP == domain 11 score: 13.2 bits; conditional E-value: 0.0077 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+rtl++H + v++l s+ + ++G D v +W+ sp|Q12788|TBL3_HUMAN 596 ECVRTLDAHeDKVWGLHCSRLDDHALTGASDSRVILWK 633 7********666****99999999999*55*******6 PP >> sp|Q5JTN6|WDR38_HUMAN WD repeat-containing protein 38 OS=Homo sapiens GN=WDR38 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.0 1.3e-05 0.0011 5 37 .. 15 48 .. 12 49 .. 0.86 2 ! 33.1 0.4 3.9e-09 3.2e-07 1 38 [] 53 91 .. 53 91 .. 0.93 3 ! 39.7 0.0 3.3e-11 2.7e-09 2 38 .] 96 133 .. 95 133 .. 0.96 4 ! 27.6 0.8 2.3e-07 1.8e-05 2 38 .] 138 175 .. 137 175 .. 0.94 5 ! 28.7 0.8 9.8e-08 8e-06 7 38 .] 188 219 .. 183 219 .. 0.89 6 ! 30.5 0.1 2.6e-08 2.1e-06 3 38 .] 225 261 .. 223 261 .. 0.93 7 ? 11.6 0.0 0.026 2.1 1 33 [. 265 298 .. 265 298 .. 0.75 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.3e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + + H + v+s afspdg++l++Gs+Dg v+ W sp|Q5JTN6|WDR38_HUMAN 15 KFFGQHgGEVNSSAFSPDGQMLLTGSEDGCVYGW 48 567789666*********************9877 PP == domain 2 score: 33.1 bits; conditional E-value: 3.9e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq+l+ l GH ++v ++fspdg+++as+s D+tvr+Wd sp|Q5JTN6|WDR38_HUMAN 53 GQLLWRLGGHtGPVKFCRFSPDGHLFASASCDCTVRLWD 91 688999****888*9999*********9988*******9 PP == domain 3 score: 39.7 bits; conditional E-value: 3.3e-11 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +clr+l+GH sv ++fspd++ lasG++D+ v++Wd sp|Q5JTN6|WDR38_HUMAN 96 KCLRVLKGHqRSVETVSFSPDSRQLASGGWDKRVMLWD 133 8********777*************************9 PP == domain 4 score: 27.6 bits; conditional E-value: 2.3e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q lr l GH +s+ s +fsp + la+Gs+D tv+iWd sp|Q5JTN6|WDR38_HUMAN 138 QMLRLLVGHrDSIQSSDFSPTVNCLATGSWDSTVHIWD 175 7788899**999*************************9 PP == domain 5 score: 28.7 bits; conditional E-value: 9.8e-08 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+GH ++++l++s +g + asGs+D+t++iW+ sp|Q5JTN6|WDR38_HUMAN 188 LEGHsANISCLCYSASGLL-ASGSWDKTIHIWK 219 89**655************.79**********6 PP == domain 6 score: 30.5 bits; conditional E-value: 2.6e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l l+GH ++v s+afspd wlas+++ + v++Wd sp|Q5JTN6|WDR38_HUMAN 225 LLIQLKGHvTWVKSIAFSPDELWLASAGYSRMVKVWD 261 56779***999**************9999*******9 PP == domain 7 score: 11.6 bits; conditional E-value: 0.026 TEEEEEEESSSSEEEEE....EETTSSEEEEEETTSE CS WD40 1 gqclrtltGHssvtsla....fspdgawlasGsdDgt 33 g+cl tl+G v ++a f pdg+ l+sG D+t sp|Q5JTN6|WDR38_HUMAN 265 GKCLETLKG---VLDVAhtcaFTPDGKILVSGAADQT 298 578888886...444444444***********98986 PP >> tr|C9JLV4|C9JLV4_HUMAN Apoptotic protease-activating factor 1 OS=Homo sapiens GN=APAF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0045 0.37 8 37 .. 612 642 .. 605 643 .. 0.86 2 ! 30.5 0.0 2.8e-08 2.2e-06 2 38 .] 648 685 .. 647 685 .. 0.91 3 ! 22.9 0.8 6.7e-06 0.00054 1 38 [] 689 729 .. 689 729 .. 0.82 4 ! 35.7 0.2 6.2e-10 5e-08 3 38 .] 735 771 .. 733 771 .. 0.91 5 ? 7.6 0.0 0.47 38 13 38 .] 801 825 .. 792 825 .. 0.91 6 ! 28.8 0.6 9.3e-08 7.5e-06 4 37 .. 832 866 .. 829 867 .. 0.92 7 ! 12.9 0.1 0.0095 0.77 9 38 .] 958 988 .. 949 988 .. 0.89 8 ? 10.7 0.1 0.047 3.8 7 38 .] 997 1028 .. 992 1028 .. 0.85 9 ! 14.6 0.5 0.0028 0.22 4 38 .] 1035 1070 .. 1032 1070 .. 0.87 10 ! 16.6 0.1 0.00064 0.052 9 38 .] 1090 1118 .. 1082 1118 .. 0.86 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0045 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 + H + v++ +fs dg+ +as++ D+t+ ++ tr|C9JLV4|C9JLV4_HUMAN 612 RPHtDAVYHACFSEDGQRIASCGADKTLQVF 642 569566****************99***9886 PP == domain 2 score: 30.5 bits; conditional E-value: 2.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l ++++H + v ++afs d +++a++s D++v+iW+ tr|C9JLV4|C9JLV4_HUMAN 648 EKLLEIKAHeDEVLCCAFSTDDRFIATCSVDKKVKIWN 685 6677889**777*************************8 PP == domain 3 score: 22.9 bits; conditional E-value: 6.7e-06 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 g++++t++ H v+++ f +++ la+Gs D+ +++Wd tr|C9JLV4|C9JLV4_HUMAN 689 GELVHTYDEHsEQVNCCHFTNSSHHllLATGSSDCFLKLWD 729 6799******555****977777774468**99*******9 PP == domain 4 score: 35.7 bits; conditional E-value: 6.2e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c t GH +sv++++fspd ++las+s Dgt+++Wd tr|C9JLV4|C9JLV4_HUMAN 735 CRNTMFGHtNSVNHCRFSPDDKLLASCSADGTLKLWD 771 566666**999*************************9 PP == domain 5 score: 7.6 bits; conditional E-value: 0.47 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v ++++s dga ++ + ++++ +W+ tr|C9JLV4|C9JLV4_HUMAN 801 VKCCSWSADGARIMVAA-KNKIFLWN 825 68***********9999.*******8 PP == domain 6 score: 28.8 bits; conditional E-value: 9.3e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + ++GH s+v+++ fspdg+ ++++sdD+t+r+W tr|C9JLV4|C9JLV4_HUMAN 832 VADCRGHlSWVHGVMFSPDGSSFLTSSDDQTIRLW 866 66789****************************** PP == domain 7 score: 12.9 bits; conditional E-value: 0.0095 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H + v++++f d + l+s+sdD + +W+ tr|C9JLV4|C9JLV4_HUMAN 958 QHkKTVWHIQFTADEKTLISSSDDAEIQVWN 988 59788*************************8 PP == domain 8 score: 10.7 bits; conditional E-value: 0.047 EESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 l+GH v +++ +++++l + s Dgtv++W+ tr|C9JLV4|C9JLV4_HUMAN 997 LRGHqETVKDFRLLKNSRLL--SwSFDGTVKVWN 1028 79**766****999999998..5566*******8 PP == domain 9 score: 14.6 bits; conditional E-value: 0.0028 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + H + v s++ s+d + ++s s D+t +iW+ tr|C9JLV4|C9JLV4_HUMAN 1035 EKDFVCHqGTVLSCDISHDATKFSSTSADKTAKIWN 1070 5668899666*************98899*******8 PP == domain 10 score: 16.6 bits; conditional E-value: 0.00064 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H ++vt+l+fspdg++l+s g ++ W+ tr|C9JLV4|C9JLV4_HUMAN 1090 THgGWVTDLCFSPDGKMLIS-A-GGYIKWWN 1118 58777*************95.6.88888887 PP >> sp|O14727-5|APAF_HUMAN Isoform 5 of Apoptotic protease-activating factor 1 OS=Homo sapiens GN=APAF1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0046 0.37 8 37 .. 620 650 .. 613 651 .. 0.86 2 ! 30.4 0.0 2.8e-08 2.3e-06 2 38 .] 656 693 .. 655 693 .. 0.91 3 ! 22.9 0.8 6.7e-06 0.00055 1 38 [] 697 737 .. 697 737 .. 0.82 4 ! 35.7 0.2 6.3e-10 5.1e-08 3 38 .] 743 779 .. 741 779 .. 0.91 5 ? 7.6 0.0 0.47 38 13 38 .] 809 833 .. 800 833 .. 0.91 6 ! 28.8 0.6 9.4e-08 7.6e-06 4 37 .. 840 874 .. 837 875 .. 0.92 7 ! 12.9 0.1 0.0095 0.77 9 38 .] 966 996 .. 957 996 .. 0.89 8 ? 10.7 0.1 0.047 3.8 7 38 .] 1005 1036 .. 1000 1036 .. 0.85 9 ! 14.6 0.5 0.0028 0.23 4 38 .] 1043 1078 .. 1040 1078 .. 0.87 10 ! 16.6 0.1 0.00065 0.053 9 38 .] 1098 1126 .. 1090 1126 .. 0.86 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0046 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 + H + v++ +fs dg+ +as++ D+t+ ++ sp|O14727-5|APAF_HUMAN 620 RPHtDAVYHACFSEDGQRIASCGADKTLQVF 650 569566****************99***9886 PP == domain 2 score: 30.4 bits; conditional E-value: 2.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l ++++H + v ++afs d +++a++s D++v+iW+ sp|O14727-5|APAF_HUMAN 656 EKLLEIKAHeDEVLCCAFSTDDRFIATCSVDKKVKIWN 693 6677889**777*************************8 PP == domain 3 score: 22.9 bits; conditional E-value: 6.7e-06 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 g++++t++ H v+++ f +++ la+Gs D+ +++Wd sp|O14727-5|APAF_HUMAN 697 GELVHTYDEHsEQVNCCHFTNSSHHllLATGSSDCFLKLWD 737 6799******555****977777774468**99*******9 PP == domain 4 score: 35.7 bits; conditional E-value: 6.3e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c t GH +sv++++fspd ++las+s Dgt+++Wd sp|O14727-5|APAF_HUMAN 743 CRNTMFGHtNSVNHCRFSPDDKLLASCSADGTLKLWD 779 566666**999*************************9 PP == domain 5 score: 7.6 bits; conditional E-value: 0.47 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v ++++s dga ++ + ++++ +W+ sp|O14727-5|APAF_HUMAN 809 VKCCSWSADGARIMVAA-KNKIFLWN 833 68***********9999.*******8 PP == domain 6 score: 28.8 bits; conditional E-value: 9.4e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + ++GH s+v+++ fspdg+ ++++sdD+t+r+W sp|O14727-5|APAF_HUMAN 840 VADCRGHlSWVHGVMFSPDGSSFLTSSDDQTIRLW 874 66789****************************** PP == domain 7 score: 12.9 bits; conditional E-value: 0.0095 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H + v++++f d + l+s+sdD + +W+ sp|O14727-5|APAF_HUMAN 966 QHkKTVWHIQFTADEKTLISSSDDAEIQVWN 996 59788*************************8 PP == domain 8 score: 10.7 bits; conditional E-value: 0.047 EESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 l+GH v +++ +++++l + s Dgtv++W+ sp|O14727-5|APAF_HUMAN 1005 LRGHqETVKDFRLLKNSRLL--SwSFDGTVKVWN 1036 79**766****999999998..5566*******8 PP == domain 9 score: 14.6 bits; conditional E-value: 0.0028 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + H + v s++ s+d + ++s s D+t +iW+ sp|O14727-5|APAF_HUMAN 1043 EKDFVCHqGTVLSCDISHDATKFSSTSADKTAKIWN 1078 5668899666*************98899*******8 PP == domain 10 score: 16.6 bits; conditional E-value: 0.00065 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H ++vt+l+fspdg++l+s g ++ W+ sp|O14727-5|APAF_HUMAN 1098 THgGWVTDLCFSPDGKMLIS-A-GGYIKWWN 1126 58777*************95.6.88888887 PP >> sp|O75529|TAF5L_HUMAN TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 0.019 1.5 18 38 .] 276 296 .. 252 296 .. 0.84 2 ! 20.3 0.0 4.4e-05 0.0035 2 38 .] 333 370 .. 332 370 .. 0.93 3 ! 26.3 0.1 5.6e-07 4.6e-05 7 38 .] 380 412 .. 374 412 .. 0.89 4 ! 39.7 0.0 3.3e-11 2.7e-09 3 38 .] 418 454 .. 416 454 .. 0.96 5 ! 36.3 0.0 3.9e-10 3.1e-08 2 38 .] 459 496 .. 458 496 .. 0.94 6 ! 36.9 0.1 2.6e-10 2.1e-08 4 38 .] 503 538 .. 500 538 .. 0.91 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.019 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 spd+++la+G d+ +++W+ sp|O75529|TAF5L_HUMAN 276 ISPDSKLLAAGFDNSCIKLWS 296 7**********99*******5 PP == domain 2 score: 20.3 bits; conditional E-value: 4.4e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++l+GH ++v+s +f d++ l+s+s+D ++r Wd sp|O75529|TAF5L_HUMAN 333 TEMKILRGHcGPVYSTRFLADSSGLLSCSEDMSIRYWD 370 56899****888*************************9 PP == domain 3 score: 26.3 bits; conditional E-value: 5.6e-07 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH +v++l+ sp++ ++asGs D+t r+W+ sp|O75529|TAF5L_HUMAN 380 YQGHaYPVWDLDISPYSLYFASGSHDRTARLWS 412 78**777****************99*******5 PP == domain 4 score: 39.7 bits; conditional E-value: 3.3e-11 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +lr++ GH +v +++f+p++++la+Gs D+tvr+W+ sp|O75529|TAF5L_HUMAN 418 PLRIYAGHlADVDCVKFHPNSNYLATGSTDKTVRLWS 454 799*********************************5 PP == domain 5 score: 36.3 bits; conditional E-value: 3.9e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r +tGH ++v slafsp+g++las+++D+ +++Wd sp|O75529|TAF5L_HUMAN 459 NSVRLFTGHrGPVLSLAFSPNGKYLASAGEDQRLKLWD 496 67899****999*************************9 PP == domain 6 score: 36.9 bits; conditional E-value: 2.6e-10 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH +++tsl fspd+ ++as+s+D++vr+Wd sp|O75529|TAF5L_HUMAN 503 YKELRGHtDNITSLTFSPDSGLIASASMDNSVRVWD 538 5789***766*************************9 PP >> sp|O60907-2|TBL1X_HUMAN Isoform 2 of F-box-like/WD repeat-containing protein TBL1X OS=Homo sapiens GN=TBL1X # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.1 2.2e-06 0.00018 5 38 .] 175 209 .. 172 209 .. 0.91 2 ! 27.3 0.3 2.8e-07 2.3e-05 3 37 .. 226 264 .. 222 265 .. 0.82 3 ! 20.5 0.1 3.8e-05 0.0031 4 38 .] 271 306 .. 268 306 .. 0.89 4 ? 4.3 0.0 5.2 4.2e+02 7 36 .. 316 345 .. 310 345 .. 0.75 5 ! 37.6 0.0 1.5e-10 1.2e-08 2 38 .] 352 389 .. 351 389 .. 0.95 6 ! 24.3 0.1 2.3e-06 0.00019 2 38 .] 394 440 .. 393 440 .. 0.91 7 ! 40.6 0.2 1.7e-11 1.3e-09 1 38 [] 444 482 .. 444 482 .. 0.96 8 ? 11.5 0.3 0.027 2.2 1 36 [. 486 521 .. 486 523 .. 0.92 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 2.2e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH s v +a++p +++lasGs D t riW+ sp|O60907-2|TBL1X_HUMAN 175 TVLRGHeSEVFICAWNPVSDLLASGSGDSTARIWN 209 579***88898889***********99*******8 PP == domain 2 score: 27.3 bits; conditional E-value: 2.8e-07 EEEEEESS.SS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ss....vtslafspdgawlasGsdDgtvriW 37 c+r+ GH + vtsl+++ +g++la+Gs+Dg riW sp|O60907-2|TBL1X_HUMAN 226 CIRE-GGHdVPsnkdVTSLDWNTNGTLLATGSYDGFARIW 264 5555.4997224567************************* PP == domain 3 score: 20.5 bits; conditional E-value: 3.8e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl H +++ +l++++ g++++s++ D+t iWd sp|O60907-2|TBL1X_HUMAN 271 ASTLGQHkGPIFALKWNRKGNYILSAGVDKTTIIWD 306 5689999777**************9999*******9 PP == domain 4 score: 4.3 bits; conditional E-value: 5.2 EESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvri 36 + H + +++++ + ++ as+s D +++ sp|O60907-2|TBL1X_HUMAN 316 FPFHsAPALDVDWQNNTTF-ASCSTDMCIHV 345 5667444569999999999.78888*99875 PP == domain 5 score: 37.6 bits; conditional E-value: 1.5e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++t+ GH + v++++++p+g +las+sdD t++iW+ sp|O60907-2|TBL1X_HUMAN 352 RPVKTFQGHtNEVNAIKWDPSGMLLASCSDDMTLKIWS 389 5899*****999*************************5 PP == domain 6 score: 24.3 bits; conditional E-value: 2.3e-06 EEEEEEESS.SSEEEEEEETTSSE.........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.........lasGsdDgtvriWd 38 c++ l +H + ++ +++sp g+ las+s D tvr+Wd sp|O60907-2|TBL1X_HUMAN 394 VCIHDLQAHnKEIYTIKWSPTGPAtsnpnsnimLASASFDSTVRLWD 440 69*******888*****9999999999999988999999*******9 PP == domain 7 score: 40.6 bits; conditional E-value: 1.7e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g c++tlt H +v+s+afspdg++lasGs D+ v+iW+ sp|O60907-2|TBL1X_HUMAN 444 GVCTHTLTKHqEPVYSVAFSPDGKYLASGSFDKCVHIWN 482 579*******888*************************8 PP == domain 8 score: 11.5 bits; conditional E-value: 0.027 TEEEEEEESSSSEEEEEEETTSSEE.EEEETTSEEEE CS WD40 1 gqclrtltGHssvtslafspdgawl.asGsdDgtvri 36 g+++++++G +++ ++++ g+ + as+s Dg+v + sp|O60907-2|TBL1X_HUMAN 486 GNLVHSYRGTGGIFEVCWNARGDKVgASAS-DGSVCV 521 6899******99************988899.***987 PP >> sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD repeat-containing protein TBL1XR1 OS=Homo sapiens GN=TBL1XR1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 0.1 3.1e-06 0.00025 6 38 .] 164 197 .. 160 197 .. 0.91 2 ! 23.7 0.1 3.7e-06 0.0003 11 37 .. 226 252 .. 211 253 .. 0.83 3 ! 20.6 0.1 3.5e-05 0.0028 4 38 .] 259 294 .. 256 294 .. 0.89 4 ? 5.8 0.1 1.7 1.4e+02 7 36 .. 304 333 .. 298 334 .. 0.77 5 ! 39.4 0.1 4e-11 3.3e-09 2 38 .] 340 377 .. 339 377 .. 0.95 6 ! 25.0 0.1 1.5e-06 0.00012 2 38 .] 382 428 .. 381 428 .. 0.90 7 ! 40.3 0.2 2.1e-11 1.7e-09 3 38 .] 434 470 .. 432 470 .. 0.95 8 ? 10.5 0.3 0.054 4.4 2 36 .. 475 509 .. 474 511 .. 0.91 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 3.1e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH s v +a++p +++lasGs D t riW+ sp|Q9BZK7|TBL1R_HUMAN 164 VLRGHeSEVFICAWNPVSDLLASGSGDSTARIWN 197 689**88898889***********99*******8 PP == domain 2 score: 23.7 bits; conditional E-value: 3.7e-06 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 ++vtsl+++++g++la+Gs+Dg riW sp|Q9BZK7|TBL1R_HUMAN 226 KDVTSLDWNSEGTLLATGSYDGFARIW 252 56************************* PP == domain 3 score: 20.6 bits; conditional E-value: 3.5e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl H +++ +l++++ g++++s++ D+t iWd sp|Q9BZK7|TBL1R_HUMAN 259 ASTLGQHkGPIFALKWNKKGNFILSAGVDKTTIIWD 294 5689999777**************9999*******9 PP == domain 4 score: 5.8 bits; conditional E-value: 1.7 EESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvri 36 + H + ++++++++++ as+s D +++ sp|Q9BZK7|TBL1R_HUMAN 304 FPFHsAPALDVDWQSNNTF-ASCSTDMCIHV 333 56674445699********.68888*99876 PP == domain 5 score: 39.4 bits; conditional E-value: 4e-11 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++t+ GH + v++++++p g++las+sdD t++iW+ sp|Q9BZK7|TBL1R_HUMAN 340 RPIKTFQGHtNEVNAIKWDPTGNLLASCSDDMTLKIWS 377 5899*****999*************************5 PP == domain 6 score: 25.0 bits; conditional E-value: 1.5e-06 EEEEEEESS.SSEEEEEEETTSSE.........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.........lasGsdDgtvriWd 38 +c++ l +H + ++ +++sp g+ las+s D tvr+Wd sp|Q9BZK7|TBL1R_HUMAN 382 NCVHDLQAHnKEIYTIKWSPTGPGtnnpnanlmLASASFDSTVRLWD 428 79*******888*****8888888888888888899999*******9 PP == domain 7 score: 40.3 bits; conditional E-value: 2.1e-11 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c++tlt H +v+s+afspdg++lasGs D+ v+iW+ sp|Q9BZK7|TBL1R_HUMAN 434 CIHTLTKHqEPVYSVAFSPDGRYLASGSFDKCVHIWN 470 9*******888*************************8 PP == domain 8 score: 10.5 bits; conditional E-value: 0.054 EEEEEEESSSSEEEEEEETTSSEE.EEEETTSEEEE CS WD40 2 qclrtltGHssvtslafspdgawl.asGsdDgtvri 36 ++++++G +++ ++++ g+ + as+s Dg+v + sp|Q9BZK7|TBL1R_HUMAN 475 ALVHSYRGTGGIFEVCWNAAGDKVgASAS-DGSVCV 509 579******99************988899.***987 PP >> sp|O60907|TBL1X_HUMAN F-box-like/WD repeat-containing protein TBL1X OS=Homo sapiens GN=TBL1X PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.1 2.4e-06 0.0002 5 38 .] 226 260 .. 223 260 .. 0.91 2 ! 27.1 0.3 3.2e-07 2.6e-05 3 37 .. 277 315 .. 273 316 .. 0.82 3 ! 20.3 0.1 4.3e-05 0.0035 4 38 .] 322 357 .. 319 357 .. 0.89 4 ? 4.1 0.0 5.8 4.7e+02 7 36 .. 367 396 .. 361 396 .. 0.75 5 ! 37.5 0.0 1.6e-10 1.3e-08 2 38 .] 403 440 .. 402 440 .. 0.95 6 ! 24.2 0.1 2.7e-06 0.00022 2 38 .] 445 491 .. 444 491 .. 0.91 7 ! 40.5 0.2 1.9e-11 1.5e-09 1 38 [] 495 533 .. 495 533 .. 0.96 8 ? 11.3 0.3 0.03 2.5 1 36 [. 537 572 .. 537 574 .. 0.92 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 2.4e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH s v +a++p +++lasGs D t riW+ sp|O60907|TBL1X_HUMAN 226 TVLRGHeSEVFICAWNPVSDLLASGSGDSTARIWN 260 579***88898889***********99*******8 PP == domain 2 score: 27.1 bits; conditional E-value: 3.2e-07 EEEEEESS.SS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ss....vtslafspdgawlasGsdDgtvriW 37 c+r+ GH + vtsl+++ +g++la+Gs+Dg riW sp|O60907|TBL1X_HUMAN 277 CIRE-GGHdVPsnkdVTSLDWNTNGTLLATGSYDGFARIW 315 5555.4997224567************************* PP == domain 3 score: 20.3 bits; conditional E-value: 4.3e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl H +++ +l++++ g++++s++ D+t iWd sp|O60907|TBL1X_HUMAN 322 ASTLGQHkGPIFALKWNRKGNYILSAGVDKTTIIWD 357 5689999777**************9999*******9 PP == domain 4 score: 4.1 bits; conditional E-value: 5.8 EESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvri 36 + H + +++++ + ++ as+s D +++ sp|O60907|TBL1X_HUMAN 367 FPFHsAPALDVDWQNNTTF-ASCSTDMCIHV 396 5667444569999999999.78888*99875 PP == domain 5 score: 37.5 bits; conditional E-value: 1.6e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++t+ GH + v++++++p+g +las+sdD t++iW+ sp|O60907|TBL1X_HUMAN 403 RPVKTFQGHtNEVNAIKWDPSGMLLASCSDDMTLKIWS 440 5899*****999*************************5 PP == domain 6 score: 24.2 bits; conditional E-value: 2.7e-06 EEEEEEESS.SSEEEEEEETTSSE.........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.........lasGsdDgtvriWd 38 c++ l +H + ++ +++sp g+ las+s D tvr+Wd sp|O60907|TBL1X_HUMAN 445 VCIHDLQAHnKEIYTIKWSPTGPAtsnpnsnimLASASFDSTVRLWD 491 69*******888*****9999999999999988999999*******9 PP == domain 7 score: 40.5 bits; conditional E-value: 1.9e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g c++tlt H +v+s+afspdg++lasGs D+ v+iW+ sp|O60907|TBL1X_HUMAN 495 GVCTHTLTKHqEPVYSVAFSPDGKYLASGSFDKCVHIWN 533 579*******888*************************8 PP == domain 8 score: 11.3 bits; conditional E-value: 0.03 TEEEEEEESSSSEEEEEEETTSSEE.EEEETTSEEEE CS WD40 1 gqclrtltGHssvtslafspdgawl.asGsdDgtvri 36 g+++++++G +++ ++++ g+ + as+s Dg+v + sp|O60907|TBL1X_HUMAN 537 GNLVHSYRGTGGIFEVCWNARGDKVgASAS-DGSVCV 572 6899******99************988899.***987 PP >> tr|J3KNP2|J3KNP2_HUMAN Transducin beta-like protein 3 (Fragment) OS=Homo sapiens GN=TBL3 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.1 1.7e-05 0.0014 10 38 .] 16 45 .. 9 45 .. 0.91 2 ? 11.1 0.2 0.035 2.8 5 38 .] 48 89 .. 46 89 .. 0.67 3 ! 31.6 0.2 1.2e-08 1e-06 2 38 .] 94 131 .. 93 131 .. 0.96 4 ? 6.3 0.0 1.2 98 24 37 .. 169 182 .. 156 183 .. 0.76 5 ! 13.8 0.4 0.0051 0.41 5 37 .. 278 311 .. 274 312 .. 0.77 6 ? 10.6 0.0 0.051 4.1 23 37 .. 324 338 .. 321 338 .. 0.92 7 ! 25.3 0.0 1.2e-06 9.4e-05 4 37 .. 361 395 .. 358 395 .. 0.92 8 ! 29.9 0.1 4.1e-08 3.3e-06 2 37 .. 401 437 .. 400 437 .. 0.95 9 ! 24.7 0.1 1.9e-06 0.00015 2 37 .. 443 479 .. 442 480 .. 0.82 10 ! 13.5 0.5 0.0064 0.52 2 38 .] 485 522 .. 484 522 .. 0.89 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.7e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +v +af+p +++la+G+ Dg vr+Wd tr|J3KNP2|J3KNP2_HUMAN 16 HtAPVATMAFDPTSTLLATGGCDGAVRVWD 45 65669999************88*******9 PP == domain 2 score: 11.1 bits; conditional E-value: 0.035 EEEESS.SS.....EEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 5 rtltGH.ss.....vtslafspdgawla..sGsdDgtvriWd 38 r++ +H + v+ +af+pd + l+ s+ D +r+W+ tr|J3KNP2|J3KNP2_HUMAN 48 RHYGTHhFRgspgvVHLVAFHPDPTRLLlfSSATDAAIRVWS 89 5565554113357567777*******64447666*******5 PP == domain 3 score: 31.6 bits; conditional E-value: 1.2e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl +lt+H s vtslafs dg+ ++s+++D+ + iWd tr|J3KNP2|J3KNP2_HUMAN 94 SCLAVLTAHySAVTSLAFSADGHTMLSSGRDKICIIWD 131 79*******999*************99999*******9 PP == domain 4 score: 6.3 bits; conditional E-value: 1.2 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 ++++++d gt+r+W tr|J3KNP2|J3KNP2_HUMAN 169 YFLTAGDQGTLRVW 182 4456777******* PP == domain 5 score: 13.8 bits; conditional E-value: 0.0051 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriW 37 ++l GH++ v +l++ + g ++as+ +D++vriW tr|J3KNP2|J3KNP2_HUMAN 278 QILHGHTDiVLALDVFRKGWLFASCAKDQSVRIW 311 5788**66479996555544478999******** PP == domain 6 score: 10.6 bits; conditional E-value: 0.051 SEEEEEETTSEEEEE CS WD40 23 awlasGsdDgtvriW 37 ++l++Gs D+tv++W tr|J3KNP2|J3KNP2_HUMAN 324 SFLVTGSQDCTVKLW 338 5799*********** PP == domain 7 score: 25.3 bits; conditional E-value: 1.2e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++t + H ++++s+a p+ ++la+Gs D+t ++W tr|J3KNP2|J3KNP2_HUMAN 361 QTTQRCHdKDINSVAIAPNDKLLATGSQDRTAKLW 395 667789*999************************* PP == domain 8 score: 29.9 bits; conditional E-value: 4.1e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 q+l++++GH + ++++fsp + la++s Dgt+++W tr|J3KNP2|J3KNP2_HUMAN 401 QLLGVFSGHrRGLWCVQFSPMDQVLATASADGTIKLW 437 7899*****888************************* PP == domain 9 score: 24.7 bits; conditional E-value: 1.9e-06 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 +cl+t++GH sv +a +s+ ++l+sGs Dg v++W tr|J3KNP2|J3KNP2_HUMAN 443 SCLKTFEGHdASVLKVAfVSRGTQLLSSGS-DGLVKLW 479 7********888*****5555555566788.******* PP == domain 10 score: 13.5 bits; conditional E-value: 0.0064 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+rtl++H + v++l s+ + ++G D v +W+ tr|J3KNP2|J3KNP2_HUMAN 485 ECVRTLDAHeDKVWGLHCSRLDDHALTGASDSRVILWK 522 7********666****99999999999*55*******6 PP >> sp|Q96DI7|SNR40_HUMAN U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens GN=SNRNP40 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.5 0.0 5.7e-08 4.6e-06 4 38 .] 59 94 .. 56 94 .. 0.90 2 ! 22.1 0.1 1.2e-05 0.00099 5 38 .] 103 137 .. 99 137 .. 0.90 3 ! 27.2 0.0 3e-07 2.4e-05 3 38 .] 143 180 .. 141 180 .. 0.85 4 ! 14.6 0.1 0.0029 0.23 13 38 .] 196 221 .. 186 221 .. 0.87 5 ! 29.3 0.0 6.5e-08 5.3e-06 2 38 .] 226 263 .. 224 263 .. 0.90 6 ! 24.9 0.1 1.5e-06 0.00012 2 38 .] 272 313 .. 271 313 .. 0.85 7 ! 20.0 0.0 5.4e-05 0.0044 3 34 .. 319 351 .. 317 353 .. 0.87 Alignments for each domain: == domain 1 score: 29.5 bits; conditional E-value: 5.7e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + l+GH + v++++f+p+g+ las++ D+ + +W+ sp|Q96DI7|SNR40_HUMAN 59 IMLLSGHeGEVYCCKFHPNGSTLASAGFDRLILLWN 94 56689**888**************9988*******8 PP == domain 2 score: 22.1 bits; conditional E-value: 1.2e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl+GH + v l ++ dg++l+s+s D+tv +Wd sp|Q96DI7|SNR40_HUMAN 103 ATLKGHsGAVMELHYNTDGSMLFSASTDKTVAVWD 137 699***555****************99*******9 PP == domain 3 score: 27.2 bits; conditional E-value: 3e-07 EEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ l+GH s+v+s+ + g+ l+ +GsdDgtv++Wd sp|Q96DI7|SNR40_HUMAN 143 RVKRLKGHtSFVNSCYPARRGPQLVcTGSDDGTVKLWD 180 57889***888****9888888876489*********9 PP == domain 4 score: 14.6 bits; conditional E-value: 0.0029 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v ++ f++ ++ ++sG+ D+ +++Wd sp|Q96DI7|SNR40_HUMAN 196 VLAVTFNDTSDQIISGGIDNDIKVWD 221 88999********************9 PP == domain 5 score: 29.3 bits; conditional E-value: 6.5e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++t +GH +svt+l+ s++g++l+s +D+tvr+Wd sp|Q96DI7|SNR40_HUMAN 226 KLTYTMRGHaDSVTGLSLSSEGSYLLSNAMDNTVRVWD 263 5678889**988**************8778*******9 PP == domain 6 score: 24.9 bits; conditional E-value: 1.5e-06 EEEEEEESS..SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH..ss...vtslafspdgawlasGsdDgtvriWd 38 +c++++ G ++ +++spdg+ +a+Gs D+ v++Wd sp|Q96DI7|SNR40_HUMAN 272 RCVKIFQGNvhNFeknLLRCSWSPDGSKIAAGSADRFVYVWD 313 799999988544466777888********************9 PP == domain 7 score: 20.0 bits; conditional E-value: 5.4e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtv 34 l++l GH +s++ +af+pd + ++s+s D+ + sp|Q96DI7|SNR40_HUMAN 319 ILYKLPGHaGSINEVAFHPDEPIIISASSDKRL 351 578899**999*************999779987 PP >> sp|Q05BV3-2|EMAL5_HUMAN Isoform 2 of Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens GN=EML5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 0.0022 0.18 4 38 .] 54 91 .. 51 91 .. 0.90 2 ? 9.5 0.4 0.11 9.2 8 38 .] 105 136 .. 96 136 .. 0.77 3 ? 11.8 0.0 0.022 1.8 9 38 .] 235 263 .. 226 263 .. 0.67 4 ! 25.4 0.0 1.1e-06 8.6e-05 3 38 .] 316 353 .. 314 353 .. 0.86 5 ? 10.9 0.0 0.042 3.4 10 34 .. 403 432 .. 397 435 .. 0.84 6 ? 5.0 0.0 3.1 2.5e+02 2 25 .. 446 466 .. 442 469 .. 0.83 7 ? 3.5 0.4 8.9 7.2e+02 11 37 .. 519 545 .. 495 546 .. 0.76 8 ! 23.8 1.9 3.4e-06 0.00028 3 38 .] 555 592 .. 553 592 .. 0.87 9 ! 24.6 0.1 2e-06 0.00016 2 38 .] 718 757 .. 717 757 .. 0.92 10 ! 21.0 0.3 2.6e-05 0.0021 2 38 .] 762 802 .. 761 802 .. 0.86 11 ? 9.5 0.0 0.12 9.4 4 38 .] 896 929 .. 894 929 .. 0.77 12 ! 21.3 0.0 2.2e-05 0.0018 8 38 .] 994 1026 .. 988 1026 .. 0.89 13 ? 6.2 0.1 1.3 1e+02 14 33 .. 1044 1063 .. 1042 1066 .. 0.88 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 0.0022 EEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++ ++GH +++ sla +p+ ++a+G ++ + + iWd sp|Q05BV3-2|EMAL5_HUMAN 54 QKFYRGHsDDIISLALHPERVLVATGqvGKEPYICIWD 91 6779***66688**************999********9 PP == domain 2 score: 9.5 bits; conditional E-value: 0.11 ESSSSEEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlas.G..sdDgtvriWd 38 +H ++ +laf+ dg+ l+s G s ++ v +Wd sp|Q05BV3-2|EMAL5_HUMAN 105 HTH-GIACLAFDLDGQRLVSvGldS-KNAVCVWD 136 356.7************99625645.*******9 PP == domain 3 score: 11.8 bits; conditional E-value: 0.022 SS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +H ++ s+ + +a+G++Dg +r+Wd sp|Q05BV3-2|EMAL5_HUMAN 235 AHaAGIFSM--N----AceegFATGGRDGCIRLWD 263 555556666..2....2234479***********9 PP == domain 4 score: 25.4 bits; conditional E-value: 1.1e-06 EEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 + + GH + ++la++p +++ ++GsdD++vriW+ sp|Q05BV3-2|EMAL5_HUMAN 316 PFLIMQGHcEGeLWALAVHPTKPLAVTGSDDRSVRIWS 353 566778**7336*************************5 PP == domain 5 score: 10.9 bits; conditional E-value: 0.042 S.SS....EEEEEEETTSSEEEEEETTSEE CS WD40 10 H.ss....vtslafspdgawlasGsdDgtv 34 H ++ ++ l++spdg++la G+ D +v sp|Q05BV3-2|EMAL5_HUMAN 403 HiKDrkeaIHELKYSPDGTYLAVGCNDSSV 432 66556667999*************999987 PP == domain 6 score: 5.0 bits; conditional E-value: 3.1 EEEEEEESSSSEEEEEEETTSSEE CS WD40 2 qclrtltGHssvtslafspdgawl 25 +cl++l+ ++t+l++s+d+++l sp|Q05BV3-2|EMAL5_HUMAN 446 ECLGSLS---FITHLDWSSDSRYL 466 5666666...8**********996 PP == domain 7 score: 3.5 bits; conditional E-value: 8.9 SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 11 ssvtslafspdgaw....lasGsdDgtvriW 37 ++++s+ dg++ l++++d g ++++ sp|Q05BV3-2|EMAL5_HUMAN 519 NDINSV----DGNYigqvLVTADDYGIIKLF 545 357777....5555555489**99****996 PP == domain 8 score: 23.8 bits; conditional E-value: 3.4e-06 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriWd 38 + r++ GH +vt +++s+d +w++s G+ D++v W+ sp|Q05BV3-2|EMAL5_HUMAN 555 KFRKYIGHsAHVTNVRWSHDYQWVISiGGADHSVFQWK 592 578999**777************9755888*******5 PP == domain 9 score: 24.6 bits; conditional E-value: 2e-06 EEEEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 +++r + GH +++ +l +p ++++a+G ++D++++iWd sp|Q05BV3-2|EMAL5_HUMAN 718 NTQRFYLGHdDDILCLTIHPLKDYVATGqvGRDPSIHIWD 757 5688899**888****************9999*******9 PP == domain 10 score: 21.0 bits; conditional E-value: 2.6e-05 EEEEEEESS.SS.EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ss.vtslafspdgawlasG..sdDgtvriWd 38 ++l +l+GH + v++++fs dg+ las +d +tv +Wd sp|Q05BV3-2|EMAL5_HUMAN 762 KPLSILKGHhQYgVSAVDFSADGKRLASVgiDDSHTVVLWD 802 6899*****6448*************9752659*******9 PP == domain 11 score: 9.5 bits; conditional E-value: 0.12 EEEEESS.SSEEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw...lasGsdDgtvriWd 38 ++t ++H ++v s+ +a+ +++G++Dg v +Wd sp|Q05BV3-2|EMAL5_HUMAN 896 VKTVKAHdGPVFSM-----HALekgFVTGGKDGIVALWD 929 68899997779777.....333444679**********9 PP == domain 12 score: 21.3 bits; conditional E-value: 2.2e-05 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 GH + v++la++p+ + a+ sdD+t+riWd sp|Q05BV3-2|EMAL5_HUMAN 994 QGHmeGEVWGLATHPYLPICATVSDDKTLRIWD 1026 6999555**************99*********9 PP == domain 13 score: 6.2 bits; conditional E-value: 1.3 EEEEEETTSSEEEEEETTSE CS WD40 14 tslafspdgawlasGsdDgt 33 ++++fspdg+ la G Dg+ sp|Q05BV3-2|EMAL5_HUMAN 1044 RCCCFSPDGKALAVGLNDGS 1063 599**********9977997 PP >> tr|B7Z2C8|B7Z2C8_HUMAN F-box/WD repeat-containing protein 7 OS=Homo sapiens GN=FBXW7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.4 2.5e-07 2e-05 5 38 .] 198 231 .. 194 231 .. 0.83 2 ! 22.9 0.7 6.6e-06 0.00054 1 38 [] 235 271 .. 235 271 .. 0.78 3 ! 26.7 0.5 4.2e-07 3.4e-05 1 38 [] 275 311 .. 275 311 .. 0.87 4 ! 25.3 0.1 1.2e-06 9.3e-05 1 38 [] 315 351 .. 315 351 .. 0.95 5 ! 30.9 0.6 1.9e-08 1.6e-06 2 38 .] 356 391 .. 355 391 .. 0.94 6 ! 21.4 0.3 2.1e-05 0.0017 1 38 [] 395 431 .. 395 431 .. 0.76 7 ! 31.7 0.1 1.1e-08 9.1e-07 1 38 [] 435 474 .. 435 474 .. 0.88 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 2.5e-07 EEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 ++l+GH ++ +t+l + g+ ++sGsdD+t+++W+ tr|B7Z2C8|B7Z2C8_HUMAN 198 KVLKGHdDHvITCL--QFCGNRIVSGSDDNTLKVWS 231 689***66677***..66777799***********5 PP == domain 2 score: 22.9 bits; conditional E-value: 6.6e-06 TEEEEEEESS.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssv.tslafspdgawlasGsdDgtvriWd 38 g+clrtl GH ++v +s+ +d+ ++sGs D+t+++W+ tr|B7Z2C8|B7Z2C8_HUMAN 235 GKCLRTLVGHtGGVwSSQ--MRDNI-IISGSTDRTLKVWN 271 79********888*4444..33333.679**********8 PP == domain 3 score: 26.7 bits; conditional E-value: 4.2e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g+c++tl GH s v+++ ++ ++sGs+D t+r+Wd tr|B7Z2C8|B7Z2C8_HUMAN 275 GECIHTLYGHtSTVRCM------HLhekrVVSGSRDATLRVWD 311 69********777****......55555589***********9 PP == domain 4 score: 25.3 bits; conditional E-value: 1.2e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqcl++l GH v+++ + dg+ ++sG +D v++Wd tr|B7Z2C8|B7Z2C8_HUMAN 315 GQCLHVLMGHvAAVRCV--QYDGRRVVSGAYDFMVKVWD 351 79********999****..889999****99*******9 PP == domain 5 score: 30.9 bits; conditional E-value: 1.9e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl+tl GH + v+sl + dg ++sGs D ++r+Wd tr|B7Z2C8|B7Z2C8_HUMAN 356 TCLHTLQGHtNRVYSL--QFDGIHVVSGSLDTSIRVWD 391 7********999****..889999*************9 PP == domain 6 score: 21.4 bits; conditional E-value: 2.1e-05 TEEEEEEESSSSEE...EEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHssvt...slafspdgawlasGsdDgtvriWd 38 g+c++tltGH+s t l + l+sG D tv+iWd tr|B7Z2C8|B7Z2C8_HUMAN 395 GNCIHTLTGHQSLTsgmEL----KDNILVSGNADSTVKIWD 431 79********888543322....3333899*88*******9 PP == domain 7 score: 31.7 bits; conditional E-value: 1.1e-08 TEEEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 gqcl+tl G ++ vt+l + ++++++++sdDgtv++Wd tr|B7Z2C8|B7Z2C8_HUMAN 435 GQCLQTLQGPnKHqsaVTCL--QFNKNFVITSSDDGTVKLWD 474 79*****977655667****..8899***************9 PP >> sp|Q9BQ87|TBL1Y_HUMAN F-box-like/WD repeat-containing protein TBL1Y OS=Homo sapiens GN=TBL1Y PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.1 1.7e-06 0.00014 5 38 .] 173 207 .. 169 207 .. 0.90 2 ! 23.4 0.3 4.8e-06 0.00039 3 37 .. 224 262 .. 220 263 .. 0.81 3 ! 20.5 0.1 3.8e-05 0.0031 4 38 .] 269 304 .. 266 304 .. 0.89 4 ! 37.2 0.1 2e-10 1.6e-08 3 38 .] 351 387 .. 349 387 .. 0.95 5 ! 24.1 0.1 2.7e-06 0.00022 3 38 .] 393 438 .. 391 438 .. 0.92 6 ! 36.6 0.1 3.2e-10 2.6e-08 2 38 .] 443 480 .. 442 480 .. 0.94 7 ? 9.8 0.4 0.092 7.4 1 36 [. 484 519 .. 484 521 .. 0.91 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 1.7e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH s v +a++p +++lasGs D t riW+ sp|Q9BQ87|TBL1Y_HUMAN 173 TVLRGHeSEVFICAWNPVSDLLASGSGDSTARIWN 207 579***88898889***********99*******8 PP == domain 2 score: 23.4 bits; conditional E-value: 4.8e-06 EEEEEESS.SS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ss....vtslafspdgawlasGsdDgtvriW 37 c+r+ GH + vtsl++++dg++la Gs+Dg riW sp|Q9BQ87|TBL1Y_HUMAN 224 CIRE-GGHdVPsnkdVTSLDWNSDGTLLAMGSYDGFARIW 262 5555.4997224567*************99********** PP == domain 3 score: 20.5 bits; conditional E-value: 3.8e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl H +++ +l++++ g++++s++ D+t iWd sp|Q9BQ87|TBL1Y_HUMAN 269 ASTLGQHkGPIFALKWNKKGNYVLSAGVDKTTIIWD 304 5689999777**************9999*******9 PP == domain 4 score: 37.2 bits; conditional E-value: 2e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++t+ GH + v++++++p+g +las+sdD t++iW+ sp|Q9BQ87|TBL1Y_HUMAN 351 PVKTFQGHtNEVNAIKWDPSGMLLASCSDDMTLKIWS 387 799*****999*************************5 PP == domain 5 score: 24.1 bits; conditional E-value: 2.7e-06 EEEEEESS.SSEEEEEEETTSSE.........EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.........lasGsdDgtvriWd 38 c++ l +H + ++ +++sp g+ las+s D tvr+Wd sp|Q9BQ87|TBL1Y_HUMAN 393 CVHDLQAHsKEIYTIKWSPTGPAtsnpnssimLASASFDSTVRLWD 438 9*******888*****9999999999999999999999*******9 PP == domain 6 score: 36.6 bits; conditional E-value: 3.2e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c++tl H +v+s+afspdg++lasGs D+ v+iW+ sp|Q9BQ87|TBL1Y_HUMAN 443 VCTHTLMKHqEPVYSVAFSPDGKYLASGSFDKYVHIWN 480 799**999*888*************************8 PP == domain 7 score: 9.8 bits; conditional E-value: 0.092 TEEEEEEESSSSEEEEEEETTSSEE.EEEETTSEEEE CS WD40 1 gqclrtltGHssvtslafspdgawl.asGsdDgtvri 36 g++++++ G +++ ++++ g+ + as+s Dg+v + sp|Q9BQ87|TBL1Y_HUMAN 484 GSLVHSYQGTGGIFEVCWNARGDKVgASAS-DGSVCV 519 5789******99************988899.***987 PP >> sp|P63244|GBLP_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 0.00016 0.013 4 38 .] 8 44 .. 5 44 .. 0.87 2 ! 35.7 0.6 6e-10 4.9e-08 3 38 .] 55 91 .. 53 91 .. 0.93 3 ! 36.1 0.2 4.5e-10 3.6e-08 3 38 .] 97 133 .. 95 133 .. 0.93 4 ! 24.3 1.0 2.4e-06 0.00019 9 38 .] 146 178 .. 136 178 .. 0.83 5 ! 23.9 0.2 3.1e-06 0.00025 7 38 .] 188 220 .. 182 220 .. 0.86 6 ! 22.8 0.1 7.4e-06 0.0006 2 38 .] 225 260 .. 224 260 .. 0.87 7 ! 18.4 0.0 0.00018 0.015 13 37 .. 286 310 .. 273 311 .. 0.90 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 0.00016 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s+s+D+t+ +W+ sp|P63244|GBLP_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRDKTIIMWK 44 5799***666****99888888899***********6 PP == domain 2 score: 35.7 bits; conditional E-value: 6e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd sp|P63244|GBLP_HUMAN 55 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 91 7899****667************99***********9 PP == domain 3 score: 36.1 bits; conditional E-value: 4.5e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ sp|P63244|GBLP_HUMAN 97 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133 678899******************************8 PP == domain 4 score: 24.3 bits; conditional E-value: 2.4e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ sp|P63244|GBLP_HUMAN 146 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 178 79666*************989***********8 PP == domain 5 score: 23.9 bits; conditional E-value: 3.1e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd sp|P63244|GBLP_HUMAN 188 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 220 3499666*************************9 PP == domain 6 score: 22.8 bits; conditional E-value: 7.4e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+tl+G + +++l+fsp+ wl++++ ++++iWd sp|P63244|GBLP_HUMAN 225 KHLYTLDGG-DiINALCFSPNRYWLCAAT-GPSIKIWD 260 778888887.448************9888.*******9 PP == domain 7 score: 18.4 bits; conditional E-value: 0.00018 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 tsla+s dg+ l++G D+ vr+W sp|P63244|GBLP_HUMAN 286 CTSLAWSADGQTLFAGYTDNLVRVW 310 59**************88******* PP >> sp|Q969H0-4|FBXW7_HUMAN Isoform 4 of F-box/WD repeat-containing protein 7 OS=Homo sapiens GN=FBXW7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 0.4 2.8e-07 2.3e-05 5 38 .] 256 289 .. 252 289 .. 0.83 2 ! 22.7 0.7 7.5e-06 0.00061 1 38 [] 293 329 .. 293 329 .. 0.78 3 ! 26.5 0.5 4.7e-07 3.8e-05 1 38 [] 333 369 .. 333 369 .. 0.87 4 ! 25.1 0.1 1.3e-06 0.00011 1 38 [] 373 409 .. 373 409 .. 0.95 5 ! 30.8 0.6 2.2e-08 1.8e-06 2 38 .] 414 449 .. 413 449 .. 0.94 6 ! 21.2 0.3 2.3e-05 0.0019 1 38 [] 453 489 .. 453 489 .. 0.76 7 ! 31.5 0.1 1.3e-08 1e-06 1 38 [] 493 532 .. 493 532 .. 0.88 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 2.8e-07 EEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 ++l+GH ++ +t+l + g+ ++sGsdD+t+++W+ sp|Q969H0-4|FBXW7_HUMAN 256 KVLKGHdDHvITCL--QFCGNRIVSGSDDNTLKVWS 289 689***66677***..66777799***********5 PP == domain 2 score: 22.7 bits; conditional E-value: 7.5e-06 TEEEEEEESS.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssv.tslafspdgawlasGsdDgtvriWd 38 g+clrtl GH ++v +s+ +d+ ++sGs D+t+++W+ sp|Q969H0-4|FBXW7_HUMAN 293 GKCLRTLVGHtGGVwSSQ--MRDNI-IISGSTDRTLKVWN 329 79********888*4444..33333.679**********8 PP == domain 3 score: 26.5 bits; conditional E-value: 4.7e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g+c++tl GH s v+++ ++ ++sGs+D t+r+Wd sp|Q969H0-4|FBXW7_HUMAN 333 GECIHTLYGHtSTVRCM------HLhekrVVSGSRDATLRVWD 369 69********777****......55555589***********9 PP == domain 4 score: 25.1 bits; conditional E-value: 1.3e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqcl++l GH v+++ + dg+ ++sG +D v++Wd sp|Q969H0-4|FBXW7_HUMAN 373 GQCLHVLMGHvAAVRCV--QYDGRRVVSGAYDFMVKVWD 409 79********999****..889999****99*******9 PP == domain 5 score: 30.8 bits; conditional E-value: 2.2e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl+tl GH + v+sl + dg ++sGs D ++r+Wd sp|Q969H0-4|FBXW7_HUMAN 414 TCLHTLQGHtNRVYSL--QFDGIHVVSGSLDTSIRVWD 449 7********999****..889999*************9 PP == domain 6 score: 21.2 bits; conditional E-value: 2.3e-05 TEEEEEEESSSSEE...EEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHssvt...slafspdgawlasGsdDgtvriWd 38 g+c++tltGH+s t l + l+sG D tv+iWd sp|Q969H0-4|FBXW7_HUMAN 453 GNCIHTLTGHQSLTsgmEL----KDNILVSGNADSTVKIWD 489 79********888543322....3333899*88*******9 PP == domain 7 score: 31.5 bits; conditional E-value: 1.3e-08 TEEEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 gqcl+tl G ++ vt+l + ++++++++sdDgtv++Wd sp|Q969H0-4|FBXW7_HUMAN 493 GQCLQTLQGPnKHqsaVTCL--QFNKNFVITSSDDGTVKLWD 532 79*****977655667****..8899***************9 PP >> sp|Q9BVA0|KTNB1_HUMAN Katanin p80 WD40 repeat-containing subunit B1 OS=Homo sapiens GN=KATNB1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.1 0.0026 0.21 4 38 .] 13 49 .. 10 49 .. 0.88 2 ! 24.3 0.0 2.4e-06 0.00019 2 38 .] 54 91 .. 53 91 .. 0.93 3 ! 36.3 0.0 3.8e-10 3.1e-08 3 38 .] 97 133 .. 95 133 .. 0.93 4 ! 45.8 0.2 3.8e-13 3.1e-11 3 38 .] 139 175 .. 137 175 .. 0.93 5 ! 31.0 0.0 1.9e-08 1.5e-06 2 38 .] 180 217 .. 179 217 .. 0.92 6 ? 10.7 0.0 0.048 3.9 7 37 .. 227 257 .. 221 259 .. 0.82 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 0.0026 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 l+++ +H s+v+sl +g++la+G+dD+ v +W+ sp|Q9BVA0|KTNB1_HUMAN 13 LQEIVAHaSNVSSLVlGKASGRLLATGGDDCRVNLWS 49 5667799888*999999999****************5 PP == domain 2 score: 24.3 bits; conditional E-value: 2.4e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ +ltGH s+v s++ + ++++Gs g++r+Wd sp|Q9BVA0|KTNB1_HUMAN 54 NCIMSLTGHtSPVESVRLNTPEELIVAGSQSGSIRVWD 91 79*******999****98888888999**********9 PP == domain 3 score: 36.3 bits; conditional E-value: 3.8e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 lrtl GH +++sl+f+p+g ++asGs D ++++Wd sp|Q9BVA0|KTNB1_HUMAN 97 ILRTLMGHkANICSLDFHPYGEFVASGSQDTNIKLWD 133 689999**666*************************9 PP == domain 4 score: 45.8 bits; conditional E-value: 3.8e-13 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c+ ++GH + v++l+fspdg+wlas+ dD+tv++Wd sp|Q9BVA0|KTNB1_HUMAN 139 CVFRYRGHsQAVRCLRFSPDGKWLASAADDHTVKLWD 175 8889****666****************9********9 PP == domain 5 score: 31.0 bits; conditional E-value: 1.9e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + ++ GH ++v+ + f+p+ +lasGs D+t+r+Wd sp|Q9BVA0|KTNB1_HUMAN 180 KMMSEFPGHtGPVNVVEFHPNEYLLASGSSDRTIRFWD 217 567889***888****************99*******9 PP == domain 6 score: 10.7 bits; conditional E-value: 0.048 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++G ++v+s+ f+pdg l sG+ ++r++ sp|Q9BVA0|KTNB1_HUMAN 227 IEGEpGPVRSVLFNPDGCCLYSGC-QDSLRVY 257 5667677*****************.8888875 PP >> sp|Q969H0-3|FBXW7_HUMAN Isoform 3 of F-box/WD repeat-containing protein 7 OS=Homo sapiens GN=FBXW7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.2 0.4 3e-07 2.4e-05 5 38 .] 288 321 .. 284 321 .. 0.83 2 ! 22.6 0.7 8.1e-06 0.00065 1 38 [] 325 361 .. 325 361 .. 0.78 3 ! 26.4 0.5 5.1e-07 4.1e-05 1 38 [] 365 401 .. 365 401 .. 0.87 4 ! 25.1 0.1 1.4e-06 0.00011 1 38 [] 405 441 .. 405 441 .. 0.95 5 ! 30.7 0.6 2.4e-08 1.9e-06 2 38 .] 446 481 .. 445 481 .. 0.94 6 ! 21.1 0.3 2.5e-05 0.002 1 38 [] 485 521 .. 485 521 .. 0.76 7 ! 31.4 0.1 1.4e-08 1.1e-06 1 38 [] 525 564 .. 525 564 .. 0.88 Alignments for each domain: == domain 1 score: 27.2 bits; conditional E-value: 3e-07 EEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 ++l+GH ++ +t+l + g+ ++sGsdD+t+++W+ sp|Q969H0-3|FBXW7_HUMAN 288 KVLKGHdDHvITCL--QFCGNRIVSGSDDNTLKVWS 321 689***66677***..66777799***********5 PP == domain 2 score: 22.6 bits; conditional E-value: 8.1e-06 TEEEEEEESS.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssv.tslafspdgawlasGsdDgtvriWd 38 g+clrtl GH ++v +s+ +d+ ++sGs D+t+++W+ sp|Q969H0-3|FBXW7_HUMAN 325 GKCLRTLVGHtGGVwSSQ--MRDNI-IISGSTDRTLKVWN 361 79********888*4444..33333.679**********8 PP == domain 3 score: 26.4 bits; conditional E-value: 5.1e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g+c++tl GH s v+++ ++ ++sGs+D t+r+Wd sp|Q969H0-3|FBXW7_HUMAN 365 GECIHTLYGHtSTVRCM------HLhekrVVSGSRDATLRVWD 401 69********777****......55555589***********9 PP == domain 4 score: 25.1 bits; conditional E-value: 1.4e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqcl++l GH v+++ + dg+ ++sG +D v++Wd sp|Q969H0-3|FBXW7_HUMAN 405 GQCLHVLMGHvAAVRCV--QYDGRRVVSGAYDFMVKVWD 441 79********999****..889999****99*******9 PP == domain 5 score: 30.7 bits; conditional E-value: 2.4e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl+tl GH + v+sl + dg ++sGs D ++r+Wd sp|Q969H0-3|FBXW7_HUMAN 446 TCLHTLQGHtNRVYSL--QFDGIHVVSGSLDTSIRVWD 481 7********999****..889999*************9 PP == domain 6 score: 21.1 bits; conditional E-value: 2.5e-05 TEEEEEEESSSSEE...EEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHssvt...slafspdgawlasGsdDgtvriWd 38 g+c++tltGH+s t l + l+sG D tv+iWd sp|Q969H0-3|FBXW7_HUMAN 485 GNCIHTLTGHQSLTsgmEL----KDNILVSGNADSTVKIWD 521 79********888543322....3333899*88*******9 PP == domain 7 score: 31.4 bits; conditional E-value: 1.4e-08 TEEEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 gqcl+tl G ++ vt+l + ++++++++sdDgtv++Wd sp|Q969H0-3|FBXW7_HUMAN 525 GQCLQTLQGPnKHqsaVTCL--QFNKNFVITSSDDGTVKLWD 564 79*****977655667****..8899***************9 PP >> sp|Q969H0-2|FBXW7_HUMAN Isoform 2 of F-box/WD repeat-containing protein 7 OS=Homo sapiens GN=FBXW7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.1 0.4 3.1e-07 2.5e-05 5 38 .] 294 327 .. 290 327 .. 0.83 2 ! 22.6 0.7 8.2e-06 0.00066 1 38 [] 331 367 .. 331 367 .. 0.78 3 ! 26.4 0.5 5.1e-07 4.2e-05 1 38 [] 371 407 .. 371 407 .. 0.87 4 ! 25.0 0.1 1.4e-06 0.00012 1 38 [] 411 447 .. 411 447 .. 0.95 5 ! 30.7 0.6 2.4e-08 1.9e-06 2 38 .] 452 487 .. 451 487 .. 0.94 6 ! 21.1 0.3 2.5e-05 0.0021 1 38 [] 491 527 .. 491 527 .. 0.76 7 ! 31.4 0.1 1.4e-08 1.1e-06 1 38 [] 531 570 .. 531 570 .. 0.88 Alignments for each domain: == domain 1 score: 27.1 bits; conditional E-value: 3.1e-07 EEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 ++l+GH ++ +t+l + g+ ++sGsdD+t+++W+ sp|Q969H0-2|FBXW7_HUMAN 294 KVLKGHdDHvITCL--QFCGNRIVSGSDDNTLKVWS 327 689***66677***..66777799***********5 PP == domain 2 score: 22.6 bits; conditional E-value: 8.2e-06 TEEEEEEESS.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssv.tslafspdgawlasGsdDgtvriWd 38 g+clrtl GH ++v +s+ +d+ ++sGs D+t+++W+ sp|Q969H0-2|FBXW7_HUMAN 331 GKCLRTLVGHtGGVwSSQ--MRDNI-IISGSTDRTLKVWN 367 79********888*4444..33333.679**********8 PP == domain 3 score: 26.4 bits; conditional E-value: 5.1e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g+c++tl GH s v+++ ++ ++sGs+D t+r+Wd sp|Q969H0-2|FBXW7_HUMAN 371 GECIHTLYGHtSTVRCM------HLhekrVVSGSRDATLRVWD 407 69********777****......55555589***********9 PP == domain 4 score: 25.0 bits; conditional E-value: 1.4e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqcl++l GH v+++ + dg+ ++sG +D v++Wd sp|Q969H0-2|FBXW7_HUMAN 411 GQCLHVLMGHvAAVRCV--QYDGRRVVSGAYDFMVKVWD 447 79********999****..889999****99*******9 PP == domain 5 score: 30.7 bits; conditional E-value: 2.4e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl+tl GH + v+sl + dg ++sGs D ++r+Wd sp|Q969H0-2|FBXW7_HUMAN 452 TCLHTLQGHtNRVYSL--QFDGIHVVSGSLDTSIRVWD 487 7********999****..889999*************9 PP == domain 6 score: 21.1 bits; conditional E-value: 2.5e-05 TEEEEEEESSSSEE...EEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHssvt...slafspdgawlasGsdDgtvriWd 38 g+c++tltGH+s t l + l+sG D tv+iWd sp|Q969H0-2|FBXW7_HUMAN 491 GNCIHTLTGHQSLTsgmEL----KDNILVSGNADSTVKIWD 527 79********888543322....3333899*88*******9 PP == domain 7 score: 31.4 bits; conditional E-value: 1.4e-08 TEEEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 gqcl+tl G ++ vt+l + ++++++++sdDgtv++Wd sp|Q969H0-2|FBXW7_HUMAN 531 GQCLQTLQGPnKHqsaVTCL--QFNKNFVITSSDDGTVKLWD 570 79*****977655667****..8899***************9 PP >> sp|Q969H0|FBXW7_HUMAN F-box/WD repeat-containing protein 7 OS=Homo sapiens GN=FBXW7 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.4 3.5e-07 2.9e-05 5 38 .] 374 407 .. 370 407 .. 0.83 2 ! 22.4 0.7 9.4e-06 0.00077 1 38 [] 411 447 .. 411 447 .. 0.78 3 ! 26.2 0.5 5.9e-07 4.8e-05 1 38 [] 451 487 .. 451 487 .. 0.87 4 ! 24.8 0.1 1.6e-06 0.00013 1 38 [] 491 527 .. 491 527 .. 0.95 5 ! 30.5 0.6 2.8e-08 2.2e-06 2 38 .] 532 567 .. 531 567 .. 0.94 6 ! 20.9 0.3 2.9e-05 0.0024 1 38 [] 571 607 .. 571 607 .. 0.76 7 ! 31.2 0.1 1.6e-08 1.3e-06 1 38 [] 611 650 .. 611 650 .. 0.88 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 3.5e-07 EEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 ++l+GH ++ +t+l + g+ ++sGsdD+t+++W+ sp|Q969H0|FBXW7_HUMAN 374 KVLKGHdDHvITCL--QFCGNRIVSGSDDNTLKVWS 407 689***66677***..66777799***********5 PP == domain 2 score: 22.4 bits; conditional E-value: 9.4e-06 TEEEEEEESS.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssv.tslafspdgawlasGsdDgtvriWd 38 g+clrtl GH ++v +s+ +d+ ++sGs D+t+++W+ sp|Q969H0|FBXW7_HUMAN 411 GKCLRTLVGHtGGVwSSQ--MRDNI-IISGSTDRTLKVWN 447 79********888*4444..33333.679**********8 PP == domain 3 score: 26.2 bits; conditional E-value: 5.9e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g+c++tl GH s v+++ ++ ++sGs+D t+r+Wd sp|Q969H0|FBXW7_HUMAN 451 GECIHTLYGHtSTVRCM------HLhekrVVSGSRDATLRVWD 487 69********777****......55555589***********9 PP == domain 4 score: 24.8 bits; conditional E-value: 1.6e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqcl++l GH v+++ + dg+ ++sG +D v++Wd sp|Q969H0|FBXW7_HUMAN 491 GQCLHVLMGHvAAVRCV--QYDGRRVVSGAYDFMVKVWD 527 79********999****..889999****99*******9 PP == domain 5 score: 30.5 bits; conditional E-value: 2.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl+tl GH + v+sl + dg ++sGs D ++r+Wd sp|Q969H0|FBXW7_HUMAN 532 TCLHTLQGHtNRVYSL--QFDGIHVVSGSLDTSIRVWD 567 7********999****..889999*************9 PP == domain 6 score: 20.9 bits; conditional E-value: 2.9e-05 TEEEEEEESSSSEE...EEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHssvt...slafspdgawlasGsdDgtvriWd 38 g+c++tltGH+s t l + l+sG D tv+iWd sp|Q969H0|FBXW7_HUMAN 571 GNCIHTLTGHQSLTsgmEL----KDNILVSGNADSTVKIWD 607 79********888543322....3333899*88*******9 PP == domain 7 score: 31.2 bits; conditional E-value: 1.6e-08 TEEEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 gqcl+tl G ++ vt+l + ++++++++sdDgtv++Wd sp|Q969H0|FBXW7_HUMAN 611 GQCLQTLQGPnKHqsaVTCL--QFNKNFVITSSDDGTVKLWD 650 79*****977655667****..8899***************9 PP >> sp|O76071|CIAO1_HUMAN Probable cytosolic iron-sulfur protein assembly protein CIAO1 OS=Homo sapiens GN=CIAO1 PE=1 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.1 2.3e-05 0.0018 7 37 .. 11 43 .. 6 43 .. 0.84 2 ! 22.2 0.5 1.1e-05 0.00091 4 38 .] 53 89 .. 50 89 .. 0.85 3 ! 37.0 0.1 2.3e-10 1.9e-08 2 37 .. 96 132 .. 95 133 .. 0.96 4 ! 24.4 0.1 2.2e-06 0.00018 2 37 .. 141 177 .. 140 178 .. 0.95 5 ! 42.5 0.6 4.4e-12 3.6e-10 2 37 .. 185 221 .. 184 222 .. 0.94 6 ? 8.5 0.4 0.24 19 1 37 [. 241 279 .. 241 280 .. 0.75 7 ! 22.6 0.1 8.5e-06 0.00069 6 38 .] 293 332 .. 288 332 .. 0.69 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 2.3e-05 EESS.SS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ss.vtslafspdgawlasGsdDgtvriW 37 +H +s + la++p g++las++ D+ +riW sp|O76071|CIAO1_HUMAN 11 VPAHpDSrCWFLAWNPAGTLLASCGGDRRIRIW 43 56897445999***********9877******* PP == domain 2 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+ GH v+ +a+sp g++las+s D t iW+ sp|O76071|CIAO1_HUMAN 53 KSVLSeGHqRTVRKVAWSPCGNYLASASFDATTCIWK 89 556655**555****************99*******6 PP == domain 3 score: 37.0 bits; conditional E-value: 2.3e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +c++tl+GH + v s+a+ p+g++la++s+D++v +W sp|O76071|CIAO1_HUMAN 96 ECVTTLEGHeNEVKSVAWAPSGNLLATCSRDKSVWVW 132 8********999************************* PP == domain 4 score: 24.4 bits; conditional E-value: 2.2e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +c+ +l H ++v ++ ++p++ +las+s+D tv+++ sp|O76071|CIAO1_HUMAN 141 ECVSVLNSHtQDVKHVVWHPSQELLASASYDDTVKLY 177 799******999***********************98 PP == domain 5 score: 42.5 bits; conditional E-value: 4.4e-12 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c tl+GH s v+slaf+p+g+ las+sdD+tvriW sp|O76071|CIAO1_HUMAN 185 VCCATLEGHeSTVWSLAFDPSGQRLASCSDDRTVRIW 221 6889*****888************************* PP == domain 6 score: 8.5 bits; conditional E-value: 0.24 TEEEEEEESS.SS.EEEEEEETTSSE......EEEE.ETTSEEEEE CS WD40 1 gqclrtltGH.ss.vtslafspdgaw......lasG.sdDgtvriW 37 ++c+ tl+G s ++++ aw la++ + D +r++ sp|O76071|CIAO1_HUMAN 241 WKCICTLSGFhSRtIYDI------AWcqltgaLATAcG-DDAIRVF 279 68999**9775558****......77666666775516.9999996 PP == domain 7 score: 22.6 bits; conditional E-value: 8.5e-06 EEE.....SS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 6 tlt.....GH.ssvtslafspdgawl.asGsdDgtvriWd 38 +lt +H ++v+++a++p + l as+sdDg v +W+ sp|O76071|CIAO1_HUMAN 293 SLTahlhqAHsQDVNCVAWNPKEPGLlASCSDDGEVAFWK 332 5551111256555****9999999962699********95 PP >> tr|B4DQJ1|B4DQJ1_HUMAN U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens GN=SNRNP40 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 0.0 6.9e-08 5.6e-06 4 38 .] 59 94 .. 56 94 .. 0.90 2 ! 21.8 0.1 1.5e-05 0.0012 5 38 .] 103 137 .. 99 137 .. 0.90 3 ! 26.9 0.0 3.6e-07 2.9e-05 3 38 .] 143 180 .. 141 180 .. 0.85 4 ! 14.3 0.1 0.0034 0.28 13 38 .] 196 221 .. 186 221 .. 0.87 5 ! 29.0 0.0 7.8e-08 6.4e-06 2 38 .] 226 263 .. 224 263 .. 0.90 6 ! 24.7 0.1 1.8e-06 0.00015 2 38 .] 272 313 .. 271 313 .. 0.85 7 ? 10.5 0.0 0.057 4.6 3 24 .. 319 341 .. 317 361 .. 0.85 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 6.9e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + l+GH + v++++f+p+g+ las++ D+ + +W+ tr|B4DQJ1|B4DQJ1_HUMAN 59 IMLLSGHeGEVYCCKFHPNGSTLASAGFDRLILLWN 94 56689**888**************9988*******8 PP == domain 2 score: 21.8 bits; conditional E-value: 1.5e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl+GH + v l ++ dg++l+s+s D+tv +Wd tr|B4DQJ1|B4DQJ1_HUMAN 103 ATLKGHsGAVMELHYNTDGSMLFSASTDKTVAVWD 137 699***555****************99*******9 PP == domain 3 score: 26.9 bits; conditional E-value: 3.6e-07 EEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ l+GH s+v+s+ + g+ l+ +GsdDgtv++Wd tr|B4DQJ1|B4DQJ1_HUMAN 143 RVKRLKGHtSFVNSCYPARRGPQLVcTGSDDGTVKLWD 180 57889***888****9888888876489*********9 PP == domain 4 score: 14.3 bits; conditional E-value: 0.0034 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v ++ f++ ++ ++sG+ D+ +++Wd tr|B4DQJ1|B4DQJ1_HUMAN 196 VLAVTFNDTSDQIISGGIDNDIKVWD 221 88999********************9 PP == domain 5 score: 29.0 bits; conditional E-value: 7.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++t +GH +svt+l+ s++g++l+s +D+tvr+Wd tr|B4DQJ1|B4DQJ1_HUMAN 226 KLTYTMRGHaDSVTGLSLSSEGSYLLSNAMDNTVRVWD 263 5678889**988**************8778*******9 PP == domain 6 score: 24.7 bits; conditional E-value: 1.8e-06 EEEEEEESS..SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH..ss...vtslafspdgawlasGsdDgtvriWd 38 +c++++ G ++ +++spdg+ +a+Gs D+ v++Wd tr|B4DQJ1|B4DQJ1_HUMAN 272 RCVKIFQGNvhNFeknLLRCSWSPDGSKIAAGSADRFVYVWD 313 799999988544466777888********************9 PP == domain 7 score: 10.5 bits; conditional E-value: 0.057 EEEEEESS.SSEEEEEEETTSSE CS WD40 3 clrtltGH.ssvtslafspdgaw 24 l++l GH +s++ +af+pd + tr|B4DQJ1|B4DQJ1_HUMAN 319 ILYKLPGHaGSINEVAFHPDEPI 341 578899**999*********887 PP >> tr|C9JBF9|C9JBF9_HUMAN Dynein assembly factor with WDR repeat domains 1 OS=Homo sapiens GN=DAW1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 7.7e-06 0.00062 4 38 .] 85 120 .. 82 120 .. 0.92 2 ! 27.0 0.0 3.4e-07 2.7e-05 2 38 .] 125 163 .. 124 163 .. 0.92 3 ! 38.8 0.1 6.3e-11 5.1e-09 1 38 [] 167 205 .. 167 205 .. 0.95 4 ! 29.7 0.1 4.7e-08 3.8e-06 2 38 .] 210 247 .. 209 247 .. 0.90 5 ! 26.5 0.5 5e-07 4.1e-05 2 38 .] 252 289 .. 251 289 .. 0.92 6 ! 16.9 0.2 0.00053 0.043 1 32 [. 293 326 .. 293 329 .. 0.84 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 7.7e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l++H + t +a +++g+ +++Gs+D+t+++Wd tr|C9JBF9|C9JBF9_HUMAN 85 FKVLKAHiLPLTNVALNKSGSCFITGSYDRTCKLWD 120 57899**8889************************9 PP == domain 2 score: 27.0 bits; conditional E-value: 3.4e-07 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 + l tl+GH + v+++a ++p+g+ +a+Gs D+t+++W+ tr|C9JBF9|C9JBF9_HUMAN 125 EELNTLEGHrNVVYAIAfNNPYGDKIATGSFDKTCKLWS 163 6789*****7769*************************5 PP == domain 3 score: 38.8 bits; conditional E-value: 6.3e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c +t++GH + +l+f+p ++++a+Gs+D t ++Wd tr|C9JBF9|C9JBF9_HUMAN 167 GKCYHTFRGHtAEIVCLSFNPQSTLVATGSMDTTAKLWD 205 79********76699***********************9 PP == domain 4 score: 29.7 bits; conditional E-value: 4.7e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + ++tl+GHs + sl+f+ +g+ +++Gs D+tv +Wd tr|C9JBF9|C9JBF9_HUMAN 210 EEVYTLRGHSAeIISLSFNTSGDRIITGSFDHTVVVWD 247 7899*****44588***********************9 PP == domain 5 score: 26.5 bits; conditional E-value: 5e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +l GH ++s +f+ d +++++Gs+D+t+++Wd tr|C9JBF9|C9JBF9_HUMAN 252 RKVNILIGHcAEISSASFNWDCSLILTGSMDKTCKLWD 289 678899***666*************************9 PP == domain 6 score: 16.9 bits; conditional E-value: 0.00053 TEEEEEEESS.SSEEEEEEETTSSEEEEEE.TTS CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGs.dDg 32 g+c+ tltGH + + + +f+ g+++a++s dDg tr|C9JBF9|C9JBF9_HUMAN 293 GKCVATLTGHdDEILDSCFDYTGKLIATASaDDG 326 79********555*9999*********9983455 PP >> sp|Q8N136-2|DAW1_HUMAN Isoform 2 of Dynein assembly factor with WDR repeat domains 1 OS=Homo sapiens GN=DAW1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 7.7e-06 0.00062 4 38 .] 85 120 .. 82 120 .. 0.92 2 ! 27.0 0.0 3.4e-07 2.7e-05 2 38 .] 125 163 .. 124 163 .. 0.92 3 ! 38.8 0.1 6.3e-11 5.1e-09 1 38 [] 167 205 .. 167 205 .. 0.95 4 ! 29.7 0.1 4.7e-08 3.8e-06 2 38 .] 210 247 .. 209 247 .. 0.90 5 ! 26.5 0.5 5e-07 4.1e-05 2 38 .] 252 289 .. 251 289 .. 0.92 6 ! 16.9 0.2 0.00053 0.043 1 32 [. 293 326 .. 293 329 .. 0.84 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 7.7e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l++H + t +a +++g+ +++Gs+D+t+++Wd sp|Q8N136-2|DAW1_HUMAN 85 FKVLKAHiLPLTNVALNKSGSCFITGSYDRTCKLWD 120 57899**8889************************9 PP == domain 2 score: 27.0 bits; conditional E-value: 3.4e-07 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 + l tl+GH + v+++a ++p+g+ +a+Gs D+t+++W+ sp|Q8N136-2|DAW1_HUMAN 125 EELNTLEGHrNVVYAIAfNNPYGDKIATGSFDKTCKLWS 163 6789*****7769*************************5 PP == domain 3 score: 38.8 bits; conditional E-value: 6.3e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c +t++GH + +l+f+p ++++a+Gs+D t ++Wd sp|Q8N136-2|DAW1_HUMAN 167 GKCYHTFRGHtAEIVCLSFNPQSTLVATGSMDTTAKLWD 205 79********76699***********************9 PP == domain 4 score: 29.7 bits; conditional E-value: 4.7e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + ++tl+GHs + sl+f+ +g+ +++Gs D+tv +Wd sp|Q8N136-2|DAW1_HUMAN 210 EEVYTLRGHSAeIISLSFNTSGDRIITGSFDHTVVVWD 247 7899*****44588***********************9 PP == domain 5 score: 26.5 bits; conditional E-value: 5e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +l GH ++s +f+ d +++++Gs+D+t+++Wd sp|Q8N136-2|DAW1_HUMAN 252 RKVNILIGHcAEISSASFNWDCSLILTGSMDKTCKLWD 289 678899***666*************************9 PP == domain 6 score: 16.9 bits; conditional E-value: 0.00053 TEEEEEEESS.SSEEEEEEETTSSEEEEEE.TTS CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGs.dDg 32 g+c+ tltGH + + + +f+ g+++a++s dDg sp|Q8N136-2|DAW1_HUMAN 293 GKCVATLTGHdDEILDSCFDYTGKLIATASaDDG 326 79********555*9999*********9983455 PP >> tr|B4E0B6|B4E0B6_HUMAN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphata # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 1.9 1.5e+02 14 36 .. 18 40 .. 5 42 .. 0.88 2 ? 7.4 0.1 0.52 42 8 38 .] 54 83 .. 46 83 .. 0.82 3 ! 13.9 0.1 0.0046 0.38 8 38 .] 94 125 .. 87 125 .. 0.85 4 ! 14.5 0.0 0.003 0.24 10 36 .. 135 164 .. 129 166 .. 0.81 5 ? 8.6 0.0 0.21 17 7 38 .] 218 250 .. 212 250 .. 0.76 6 ? 6.0 0.0 1.4 1.2e+02 7 32 .. 256 288 .. 252 293 .. 0.71 7 ? 5.6 0.0 2 1.6e+02 15 37 .. 359 375 .. 344 375 .. 0.83 8 ! 28.9 0.2 8.5e-08 6.9e-06 3 38 .] 391 427 .. 389 427 .. 0.95 9 ! 17.4 3.4 0.00038 0.031 4 38 .] 437 472 .. 435 472 .. 0.86 10 ! 14.9 0.0 0.0022 0.18 2 38 .] 477 512 .. 476 512 .. 0.72 11 ? 5.5 0.0 2.1 1.7e+02 4 37 .. 518 561 .. 515 562 .. 0.80 12 ! 21.2 0.0 2.3e-05 0.0019 4 37 .. 569 603 .. 566 604 .. 0.91 13 ? 7.9 0.0 0.38 31 12 37 .. 620 645 .. 612 646 .. 0.79 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 1.9 EEEEEETTSSEEEEEETTSEEEE CS WD40 14 tslafspdgawlasGsdDgtvri 36 t++afs +g+ a G+ +gtv++ tr|B4E0B6|B4E0B6_HUMAN 18 TAVAFSTNGQRAAVGTANGTVYL 40 89**********9**99***986 PP == domain 2 score: 7.4 bits; conditional E-value: 0.52 ESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriWd 38 +G ++++++ f +d ++++++ Dg + +Wd tr|B4E0B6|B4E0B6_HUMAN 54 SGCDGISACLFLSDDTLFLTAF-DGLLELWD 83 55556888889999999999**.*******9 PP == domain 3 score: 13.9 bits; conditional E-value: 0.0046 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 ++H+ +t+++ spd ++la+ + g +++Wd tr|B4E0B6|B4E0B6_HUMAN 94 KAHQYqITGCCLSPDCRLLATVCLGGCLKLWD 125 689446**************9999*******9 PP == domain 4 score: 14.5 bits; conditional E-value: 0.003 S...SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 10 H...ssvtslafspdgawlasGsdDgtvri 36 H +s +++af+p+g+ +a+Gs+ g++ + tr|B4E0B6|B4E0B6_HUMAN 135 HtypKSLNCVAFHPEGQVIATGSWAGSISF 164 4334569****************9888865 PP == domain 5 score: 8.6 bits; conditional E-value: 0.21 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +H ++v + f + g l+++++Dg+v +W+ tr|B4E0B6|B4E0B6_HUMAN 218 FPAHhGFVAAALFLHAGCQLLTAGEDGKVQVWS 250 6778677865557777777889999*******5 PP == domain 6 score: 6.0 bits; conditional E-value: 1.4 EESS.SS.....EEEEEEETTSSEEEEEET.TS CS WD40 7 ltGH.ss.....vtslafspdgawlasGsd.Dg 32 +GH +s s+a spdg+ +a G + Dg tr|B4E0B6|B4E0B6_HUMAN 256 PRGHlGSlslspALSVALSPDGDRVAVGYRaDG 288 57888775544434888*********9964255 PP == domain 7 score: 5.6 bits; conditional E-value: 2 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 s + +las+s+D tv +W tr|B4E0B6|B4E0B6_HUMAN 359 S------QELLASASEDFTVQLW 375 3......4889************ PP == domain 8 score: 28.9 bits; conditional E-value: 8.5e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++l+GH ++v++++fs dg la+G++D+++ Wd tr|B4E0B6|B4E0B6_HUMAN 391 CGTELRGHeGPVSCCSFSTDGGSLATGGRDRSLLCWD 427 7789****999*************************9 PP == domain 9 score: 17.4 bits; conditional E-value: 0.00038 EEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ H ++vt++a+ +d+ +++++s Dg+v +Wd tr|B4E0B6|B4E0B6_HUMAN 437 IHSFPaCHrDWVTGCAWTKDNLLISCSS-DGSVGLWD 472 67776589889************97666.*******9 PP == domain 10 score: 14.9 bits; conditional E-value: 0.0022 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q l+ + GH s v+++ ++s s+Dgt+++Wd tr|B4E0B6|B4E0B6_HUMAN 477 QRLGQFLGHqSAVSAV--AAVEEHVVSVSRDGTLKVWD 512 6678899**7777777..222333778899*******9 PP == domain 11 score: 5.5 bits; conditional E-value: 2.1 EEEEESS.SSEEEEE........EETTSSEEE.EEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla........fspdgawla.sGsdDgtvriW 37 l+++ +H ++++++a +p + +l+ + + Dg r+W tr|B4E0B6|B4E0B6_HUMAN 518 LTSIPAHsGPISHCAaamepraaGQPGSELLVvTVGLDGATRLW 561 677889*777*666669******99999998635577******* PP == domain 12 score: 21.2 bits; conditional E-value: 2.3e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++tl GH ++v++ a+s + +++++s+Dg+vr+W tr|B4E0B6|B4E0B6_HUMAN 569 THTLLGHsGPVRAAAVSETSGLMLTASEDGSVRLW 603 68999**777************************* PP == domain 13 score: 7.9 bits; conditional E-value: 0.38 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 vt++a+ pdg++ +sG g + +W tr|B4E0B6|B4E0B6_HUMAN 620 AVTAVAWAPDGSMAVSGNQAGELILW 645 39***********9999766666666 PP >> sp|P62873|GBB1_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 OS=Homo sapiens GN=GNB1 PE=1 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.6 0.0 1.9e-06 0.00016 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 13.3 0.1 0.0072 0.58 12 38 .] 99 125 .. 86 125 .. 0.86 3 ! 18.8 0.2 0.00013 0.011 5 38 .] 137 170 .. 133 170 .. 0.90 4 ! 24.8 0.1 1.7e-06 0.00014 1 38 [] 174 212 .. 174 212 .. 0.94 5 ! 35.1 0.0 9.3e-10 7.6e-08 2 38 .] 217 254 .. 216 254 .. 0.95 6 ! 24.0 0.2 2.9e-06 0.00024 3 38 .] 260 298 .. 258 298 .. 0.85 7 ! 20.3 0.5 4.5e-05 0.0037 6 38 .] 307 340 .] 304 340 .] 0.93 Alignments for each domain: == domain 1 score: 24.6 bits; conditional E-value: 1.9e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd sp|P62873|GBB1_HUMAN 48 RRTLRGHlAKIYAMHWGTDSRLLVSASQDGKLIIWD 83 689****999*************************9 PP == domain 2 score: 13.3 bits; conditional E-value: 0.0072 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ sp|P62873|GBB1_HUMAN 99 WVMTCAYAPSGNYVACGGLDNICSIYN 125 488889*******************97 PP == domain 3 score: 18.8 bits; conditional E-value: 0.00013 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + ++++f +d++ ++s++ D t+ +Wd sp|P62873|GBB1_HUMAN 137 RELAGHtGYLSCCRFLDDNQIVTSSG-DTTCALWD 170 7899**666*************9989.*******9 PP == domain 4 score: 24.8 bits; conditional E-value: 1.7e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq+++t+tGH ++v sl+ pd ++++sG D + ++Wd sp|P62873|GBB1_HUMAN 174 GQQTTTFTGHtGDVMSLSLAPDTRLFVSGACDASAKLWD 212 68899*****888****************77*******9 PP == domain 5 score: 35.1 bits; conditional E-value: 9.3e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +t+tGH s++++++f p+g+ +a+GsdD t+r++d sp|P62873|GBB1_HUMAN 217 MCRQTFTGHeSDINAICFFPNGNAFATGSDDATCRLFD 254 5899*****999************************98 PP == domain 6 score: 24.0 bits; conditional E-value: 2.9e-06 EEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 l t++ H + +ts++fs++g++l++G dD ++ +Wd sp|P62873|GBB1_HUMAN 260 ELMTYS-HdNIicgITSVSFSKSGRLLLAGYDDFNCNVWD 298 577775.85336669************************9 PP == domain 7 score: 20.3 bits; conditional E-value: 4.5e-05 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH + v++l + +dg +a+Gs+D ++iW+ sp|P62873|GBB1_HUMAN 307 VLAGHdNRVSCLGVTDDGMAVATGSWDSFLKIWN 340 688**888*************************8 PP >> tr|B8ZZF2|B8ZZF2_HUMAN WD repeat, SAM and U-box domain-containing protein 1 OS=Homo sapiens GN=WDSUB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.2 8.6e-05 0.0069 2 37 .. 3 37 .. 2 38 .. 0.82 2 ! 27.6 0.4 2.1e-07 1.7e-05 7 38 .] 50 82 .. 44 82 .. 0.87 3 ! 22.5 0.0 9e-06 0.00073 12 38 .] 99 125 .. 86 125 .. 0.82 4 ? 12.9 0.3 0.01 0.81 15 38 .] 144 167 .. 131 167 .. 0.86 5 ! 16.3 0.1 0.00083 0.067 3 37 .. 172 217 .. 170 217 .. 0.83 6 ! 29.0 0.1 8.1e-08 6.6e-06 5 38 .] 233 267 .. 229 267 .. 0.92 7 ! 30.0 0.0 4e-08 3.2e-06 2 37 .. 272 308 .. 271 309 .. 0.91 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 8.6e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++tl H ++v+++afs ++la++s D+t+r++ tr|B8ZZF2|B8ZZF2_HUMAN 3 KLIHTLADHgDDVNCCAFSF--SLLATCSLDKTIRLY 37 5799*****888****6533..3589*********98 PP == domain 2 score: 27.6 bits; conditional E-value: 2.1e-07 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 l+ H+ v++++fsp+g+ las+s Dgt +W+ tr|B8ZZF2|B8ZZF2_HUMAN 50 LKFHTYaVHCCCFSPSGHILASCSTDGTTVLWN 82 6778335*************************8 PP == domain 3 score: 22.5 bits; conditional E-value: 9e-06 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v+ ++fspd++ lasG Dgtv +W+ tr|B8ZZF2|B8ZZF2_HUMAN 99 PVRVCQFSPDSTCLASGAADGTVVLWN 125 575555***********99*******8 PP == domain 4 score: 12.9 bits; conditional E-value: 0.01 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++afsp+g+++++Gs g + +Wd tr|B8ZZF2|B8ZZF2_HUMAN 144 ACAFSPNGSFFVTGSSCGDLTVWD 167 688***********8899999998 PP == domain 5 score: 16.3 bits; conditional E-value: 0.00083 EEEEEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 c ++ ++H ++t+++fs+ las++ D+ v+iW tr|B8ZZF2|B8ZZF2_HUMAN 172 CPHSEKAHdLGITCCDFSSQPVSdgeqglqffrLASCGQDCQVKIW 217 77777899555****86666666889999*9999************ PP == domain 6 score: 29.0 bits; conditional E-value: 8.1e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl+GH +v ++afs+dg++l+sGs D++v ++d tr|B8ZZF2|B8ZZF2_HUMAN 233 STLSGHcAPVLACAFSHDGQMLVSGSVDKSVIVYD 267 789***888***********************998 PP == domain 7 score: 30.0 bits; conditional E-value: 4e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 + l+tlt H+ vt +af p+ +la+Gs+D+tv iW tr|B8ZZF2|B8ZZF2_HUMAN 272 NILHTLTQHTRyVTTCAFAPNTLLLATGSMDKTVNIW 308 679******445************************* PP >> sp|O75083|WDR1_HUMAN WD repeat-containing protein 1 OS=Homo sapiens GN=WDR1 PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.027 2.2 7 38 .] 54 86 .. 50 86 .. 0.81 2 ? 11.3 0.0 0.032 2.6 3 32 .. 138 169 .. 136 173 .. 0.82 3 ! 25.9 0.0 7.5e-07 6.1e-05 7 38 .] 185 217 .. 179 217 .. 0.86 4 ! 24.9 1.2 1.6e-06 0.00013 8 38 .] 231 262 .. 223 262 .. 0.90 5 ! 22.4 1.4 9.7e-06 0.00079 2 38 .] 311 350 .. 310 350 .. 0.91 6 ? 11.4 0.1 0.03 2.4 8 35 .. 362 389 .. 356 390 .. 0.89 7 ? 11.0 0.0 0.04 3.2 16 37 .. 451 472 .. 437 473 .. 0.88 8 ? 9.6 0.0 0.1 8.5 11 32 .. 490 511 .. 481 517 .. 0.80 9 ! 26.6 0.1 4.4e-07 3.6e-05 6 37 .. 527 559 .. 523 560 .. 0.89 10 ? 8.4 0.5 0.25 20 9 37 .. 573 602 .. 566 603 .. 0.82 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.027 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 +t H + v ++ p+g ++asG+ g++riWd sp|O75083|WDR1_HUMAN 54 YTEHAHqVVVAKYAPSGFYIASGDVSGKLRIWD 86 66663346566799******************9 PP == domain 2 score: 11.3 bits; conditional E-value: 0.032 EEEEEESSSS.EEEEEEETTSSE.EEEEETTS CS WD40 3 clrtltGHss.vtslafspdgaw.lasGsdDg 32 ++++tGH+ ++s++ ++ ++ la+GsdD+ sp|O75083|WDR1_HUMAN 138 SVGEITGHNKvINSVDIKQSRPYrLATGSDDN 169 67889***6647***9999999999****886 PP == domain 3 score: 25.9 bits; conditional E-value: 7.5e-07 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 + Hs v++++fspdg+ +a++s Dg ++i+d sp|O75083|WDR1_HUMAN 185 IGDHSRfVNCVRFSPDGNRFATASADGQIYIYD 217 5579445************************98 PP == domain 4 score: 24.9 bits; conditional E-value: 1.6e-06 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++H ++++++++spd++ l+s+s D+t +iWd sp|O75083|WDR1_HUMAN 231 KAHdGGIYAISWSPDSTHLLSASGDKTSKIWD 262 589777*************99988*******9 PP == domain 5 score: 22.4 bits; conditional E-value: 9.7e-06 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 ++l++++GH +s+ +l ++++g + sGs Dg++ Wd sp|O75083|WDR1_HUMAN 311 KPLHVIKGHsKSIQCLTVHKNGGKsyIYSGSHDGHINYWD 350 79*******999*****88888887799**99*******9 PP == domain 6 score: 11.4 bits; conditional E-value: 0.03 ESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvr 35 +GH + v+ + ++ +g+++ s+s+D tvr sp|O75083|WDR1_HUMAN 362 KGHtNQVSRMTVDESGQLI-SCSMDDTVR 389 7**988************8.6888***98 PP == domain 7 score: 11.0 bits; conditional E-value: 0.04 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +a++p g+ +a G+ Dg+vr++ sp|O75083|WDR1_HUMAN 451 VAVHPGGDTVAIGGVDGNVRLY 472 457*****************98 PP == domain 8 score: 9.6 bits; conditional E-value: 0.1 SSEEEEEEETTSSEEEEEETTS CS WD40 11 ssvtslafspdgawlasGsdDg 32 ++vt++a+s+dga+la ++ + sp|O75083|WDR1_HUMAN 490 GPVTDVAYSHDGAFLAVCDASK 511 45*************9986555 PP == domain 9 score: 26.6 bits; conditional E-value: 4.4e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++ GH + +la+spd+ +asG++D v++W sp|O75083|WDR1_HUMAN 527 VFYGHhAKIVCLAWSPDNEHFASGGMDMMVYVW 559 6789966699*********************** PP == domain 10 score: 8.4 bits; conditional E-value: 0.25 SS..SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH..ssvtslafspdgawlasGsdDgtvriW 37 +H +v+sla+ ++++++++++ D +v+ W sp|O75083|WDR1_HUMAN 573 AHrlHHVSSLAWLDEHTLVTTSH-DASVKEW 602 555446************99989.****977 PP >> sp|Q8N9V3|WSDU1_HUMAN WD repeat, SAM and U-box domain-containing protein 1 OS=Homo sapiens GN=WDSUB1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.2 9.8e-05 0.008 2 37 .. 3 37 .. 2 38 .. 0.82 2 ! 27.5 0.4 2.4e-07 2e-05 7 38 .] 50 82 .. 44 82 .. 0.87 3 ! 22.3 0.0 1e-05 0.00083 12 38 .] 99 125 .. 86 125 .. 0.82 4 ? 12.7 0.3 0.011 0.92 15 38 .] 144 167 .. 131 167 .. 0.86 5 ! 16.1 0.1 0.00095 0.077 3 37 .. 172 217 .. 170 217 .. 0.83 6 ! 28.8 0.1 9.3e-08 7.5e-06 5 38 .] 233 267 .. 229 267 .. 0.92 7 ! 29.8 0.0 4.5e-08 3.7e-06 2 37 .. 272 308 .. 271 309 .. 0.91 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 9.8e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++tl H ++v+++afs ++la++s D+t+r++ sp|Q8N9V3|WSDU1_HUMAN 3 KLIHTLADHgDDVNCCAFSF--SLLATCSLDKTIRLY 37 5799*****888****6533..3589*********98 PP == domain 2 score: 27.5 bits; conditional E-value: 2.4e-07 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 l+ H+ v++++fsp+g+ las+s Dgt +W+ sp|Q8N9V3|WSDU1_HUMAN 50 LKFHTYaVHCCCFSPSGHILASCSTDGTTVLWN 82 6778335*************************8 PP == domain 3 score: 22.3 bits; conditional E-value: 1e-05 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v+ ++fspd++ lasG Dgtv +W+ sp|Q8N9V3|WSDU1_HUMAN 99 PVRVCQFSPDSTCLASGAADGTVVLWN 125 575555***********99*******8 PP == domain 4 score: 12.7 bits; conditional E-value: 0.011 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++afsp+g+++++Gs g + +Wd sp|Q8N9V3|WSDU1_HUMAN 144 ACAFSPNGSFFVTGSSCGDLTVWD 167 688***********8899999998 PP == domain 5 score: 16.1 bits; conditional E-value: 0.00095 EEEEEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 c ++ ++H ++t+++fs+ las++ D+ v+iW sp|Q8N9V3|WSDU1_HUMAN 172 CPHSEKAHdLGITCCDFSSQPVSdgeqglqffrLASCGQDCQVKIW 217 77777899555****86666666889999*9999************ PP == domain 6 score: 28.8 bits; conditional E-value: 9.3e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl+GH +v ++afs+dg++l+sGs D++v ++d sp|Q8N9V3|WSDU1_HUMAN 233 STLSGHcAPVLACAFSHDGQMLVSGSVDKSVIVYD 267 789***888***********************998 PP == domain 7 score: 29.8 bits; conditional E-value: 4.5e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 + l+tlt H+ vt +af p+ +la+Gs+D+tv iW sp|Q8N9V3|WSDU1_HUMAN 272 NILHTLTQHTRyVTTCAFAPNTLLLATGSMDKTVNIW 308 679******445************************* PP >> tr|H3BPK1|H3BPK1_HUMAN Katanin p80 WD40 repeat-containing subunit B1 (Fragment) OS=Homo sapiens GN=KATNB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.1 0.00054 0.044 4 38 .] 13 49 .. 10 49 .. 0.88 2 ! 26.5 0.0 4.9e-07 4e-05 2 38 .] 54 91 .. 53 91 .. 0.93 3 ! 38.5 0.0 7.9e-11 6.4e-09 3 38 .] 97 133 .. 95 133 .. 0.93 4 ! 48.0 0.2 7.9e-14 6.4e-12 3 38 .] 139 175 .. 137 175 .. 0.93 5 ! 15.6 0.0 0.0014 0.11 2 31 .. 180 210 .] 179 210 .] 0.88 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 0.00054 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 l+++ +H s+v+sl +g++la+G+dD+ v +W+ tr|H3BPK1|H3BPK1_HUMAN 13 LQEIVAHaSNVSSLVlGKASGRLLATGGDDCRVNLWS 49 6667799888*999999999****************5 PP == domain 2 score: 26.5 bits; conditional E-value: 4.9e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ +ltGH s+v s++ + ++++Gs g++r+Wd tr|H3BPK1|H3BPK1_HUMAN 54 NCIMSLTGHtSPVESVRLNTPEELIVAGSQSGSIRVWD 91 79*******999****98888888999**********9 PP == domain 3 score: 38.5 bits; conditional E-value: 7.9e-11 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 lrtl GH +++sl+f+p+g ++asGs D ++++Wd tr|H3BPK1|H3BPK1_HUMAN 97 ILRTLMGHkANICSLDFHPYGEFVASGSQDTNIKLWD 133 689999**666*************************9 PP == domain 4 score: 48.0 bits; conditional E-value: 7.9e-14 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c+ ++GH + v++l+fspdg+wlas+ dD+tv++Wd tr|H3BPK1|H3BPK1_HUMAN 139 CVFRYRGHsQAVRCLRFSPDGKWLASAADDHTVKLWD 175 8899****666****************9********9 PP == domain 5 score: 15.6 bits; conditional E-value: 0.0014 EEEEEEESS.SSEEEEEEETTSSEEEEEETT CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdD 31 + + ++ GH ++v+ + f+p+ +lasGs D tr|H3BPK1|H3BPK1_HUMAN 180 KMMSEFPGHtGPVNVVEFHPNEYLLASGSSD 210 567889***888****************866 PP >> tr|E7EP32|E7EP32_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Homo sapiens GN=GNB2 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 0.0 1.6e-06 0.00013 4 38 .] 4 39 .. 1 39 [. 0.94 2 ? 12.5 0.1 0.013 1 12 37 .. 55 80 .. 42 81 .. 0.85 3 ! 20.1 0.2 5.2e-05 0.0042 4 38 .] 92 126 .. 89 126 .. 0.90 4 ! 24.0 0.1 3e-06 0.00024 7 38 .] 136 168 .. 130 168 .. 0.87 5 ! 29.0 0.0 8.1e-08 6.6e-06 3 38 .] 174 210 .. 172 210 .. 0.96 6 ! 24.2 0.1 2.6e-06 0.00021 10 38 .] 222 254 .. 215 254 .. 0.84 7 ! 20.7 0.6 3.3e-05 0.0027 5 38 .] 262 296 .] 258 296 .] 0.92 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 1.6e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd tr|E7EP32|E7EP32_HUMAN 4 RRTLRGHlAKIYAMHWGTDSRLLVSASQDGKLIIWD 39 689****999*************************9 PP == domain 2 score: 12.5 bits; conditional E-value: 0.013 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +v +a+ p+g+++a+G+ D+ + i+ tr|E7EP32|E7EP32_HUMAN 55 WVMTCAYAPSGNFVACGGLDNICSIY 80 488889*****************998 PP == domain 3 score: 20.1 bits; conditional E-value: 5.2e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + ++++f +d++ ++s++ D t+ +Wd tr|E7EP32|E7EP32_HUMAN 92 SRELPGHtGYLSCCRFLDDNQIITSSG-DTTCALWD 126 57899**666*************9999.*******9 PP == domain 4 score: 24.0 bits; conditional E-value: 3e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH ++v sl+ pdg+ ++sG D ++++Wd tr|E7EP32|E7EP32_HUMAN 136 FAGHsGDVMSLSLAPDGRTFVSGACDASIKLWD 168 78**777****************77*******9 PP == domain 5 score: 29.0 bits; conditional E-value: 8.1e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +t+ GH s+++++af p+g +++GsdD t+r++d tr|E7EP32|E7EP32_HUMAN 174 CRQTFIGHeSDINAVAFFPNGYAFTTGSDDATCRLFD 210 889*****999************************98 PP == domain 6 score: 24.2 bits; conditional E-value: 2.6e-06 S.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ss...vtslafspdgawlasGsdDgtvriWd 38 H + +ts+afs++g++l++G dD ++ iWd tr|E7EP32|E7EP32_HUMAN 222 HdNIicgITSVAFSRSGRLLLAGYDDFNCNIWD 254 74336669************************9 PP == domain 7 score: 20.7 bits; conditional E-value: 3.3e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l GH + v++l + +dg +a+Gs+D ++iW+ tr|E7EP32|E7EP32_HUMAN 262 GVLAGHdNRVSCLGVTDDGMAVATGSWDSFLKIWN 296 5788**888*************************8 PP >> sp|Q15542-2|TAF5_HUMAN Isoform Short of Transcription initiation factor TFIID subunit 5 OS=Homo sapiens GN=TAF5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.1 0.0055 0.45 11 38 .] 471 498 .. 461 498 .. 0.81 2 ? 8.8 0.0 0.19 15 3 24 .. 535 557 .. 533 561 .. 0.85 3 ! 41.6 0.0 8.2e-12 6.6e-10 2 38 .] 563 600 .. 562 600 .. 0.97 4 ! 41.8 0.1 7.2e-12 5.8e-10 1 38 [] 604 642 .. 604 642 .. 0.95 5 ! 37.9 0.0 1.2e-10 1e-08 4 38 .] 649 684 .. 646 684 .. 0.92 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.0055 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++ t++++ +d++++a G D tvr+W+ sp|Q15542-2|TAF5_HUMAN 471 QGLTAVDVTDDSSLIAGGFADSTVRVWS 498 56899*********986668*******5 PP == domain 2 score: 8.8 bits; conditional E-value: 0.19 EEEEEESS.SSEEEEEEETTSSE CS WD40 3 clrtltGH.ssvtslafspdgaw 24 l++l GH ++v++ +fspd w sp|Q15542-2|TAF5_HUMAN 535 ELKILYGHsGPVYGASFSPDRLW 557 689999**777*********999 PP == domain 3 score: 41.6 bits; conditional E-value: 8.2e-12 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+lr++ GH +v++ +f+p+++++a+Gs D+tvr+Wd sp|Q15542-2|TAF5_HUMAN 563 QPLRIFAGHlADVNCTRFHPNSNYVATGSADRTVRLWD 600 89***********************************9 PP == domain 4 score: 41.8 bits; conditional E-value: 7.2e-12 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c+r++tGH ++++sl fsp+g++la+G Dg v +Wd sp|Q15542-2|TAF5_HUMAN 604 GNCVRIFTGHkGPIHSLTFSPNGRFLATGATDGRVLLWD 642 79********777****************88*******9 PP == domain 5 score: 37.9 bits; conditional E-value: 1.2e-10 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++l+GH + v+sl+fs+dg lasGs+D+tvr+Wd sp|Q15542-2|TAF5_HUMAN 649 VGELKGHtDTVCSLRFSRDGEILASGSMDNTVRLWD 684 5789***666*************************9 PP >> sp|Q9HAV0|GBB4_HUMAN Guanine nucleotide-binding protein subunit beta-4 OS=Homo sapiens GN=GNB4 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.0 2.9e-06 0.00023 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 13.1 0.0 0.0085 0.69 12 38 .] 99 125 .. 89 125 .. 0.88 3 ! 19.9 0.2 5.8e-05 0.0047 4 38 .] 136 170 .. 133 170 .. 0.90 4 ! 22.2 0.1 1.1e-05 0.00091 2 38 .] 175 212 .. 174 212 .. 0.92 5 ! 31.1 0.0 1.8e-08 1.4e-06 3 38 .] 218 254 .. 216 254 .. 0.95 6 ! 23.1 0.1 5.7e-06 0.00046 9 38 .] 265 298 .. 259 298 .. 0.85 7 ! 21.0 0.6 2.6e-05 0.0021 5 38 .] 306 340 .] 302 340 .] 0.92 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 2.9e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd sp|Q9HAV0|GBB4_HUMAN 48 RRTLRGHlAKIYAMHWGYDSRLLVSASQDGKLIIWD 83 689****999*************************9 PP == domain 2 score: 13.1 bits; conditional E-value: 0.0085 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ sp|Q9HAV0|GBB4_HUMAN 99 WVMTCAYAPSGNYVACGGLDNICSIYN 125 487889*******************97 PP == domain 3 score: 19.9 bits; conditional E-value: 5.8e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + ++++f +d++ ++s++ D t+ +Wd sp|Q9HAV0|GBB4_HUMAN 136 SRELPGHtGYLSCCRFLDDSQIVTSSG-DTTCALWD 170 57899**666*************9989.*******9 PP == domain 4 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+++t+tGH ++v sl+ spd + ++sG D + ++Wd sp|Q9HAV0|GBB4_HUMAN 175 QQTTTFTGHsGDVMSLSLSPDMRTFVSGACDASSKLWD 212 67889****777****************77*******9 PP == domain 5 score: 31.1 bits; conditional E-value: 1.8e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +++tGH s++++++f p+g +a+GsdD t+r++d sp|Q9HAV0|GBB4_HUMAN 218 CRQSFTGHvSDINAVSFFPNGYAFATGSDDATCRLFD 254 889********************************98 PP == domain 6 score: 23.1 bits; conditional E-value: 5.7e-06 SS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ss...vtslafspdgawlasGsdDgtvriWd 38 H + +ts+afs++g++l++G dD ++ +Wd sp|Q9HAV0|GBB4_HUMAN 265 SHdNIicgITSVAFSKSGRLLLAGYDDFNCNVWD 298 574336669************************9 PP == domain 7 score: 21.0 bits; conditional E-value: 2.6e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l GH + v++l + +dg +a+Gs+D +riW+ sp|Q9HAV0|GBB4_HUMAN 306 GVLAGHdNRVSCLGVTDDGMAVATGSWDSFLRIWN 340 5788**888*************************8 PP >> sp|P62879|GBB2_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Homo sapiens GN=GNB2 PE=1 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.6 0.0 1.9e-06 0.00016 4 38 .] 48 83 .. 45 83 .. 0.94 2 ? 12.3 0.1 0.015 1.2 12 37 .. 99 124 .. 86 125 .. 0.85 3 ! 19.8 0.2 6.4e-05 0.0052 4 38 .] 136 170 .. 133 170 .. 0.90 4 ! 23.7 0.1 3.7e-06 0.0003 7 38 .] 180 212 .. 174 212 .. 0.87 5 ! 28.7 0.0 9.9e-08 8e-06 3 38 .] 218 254 .. 216 254 .. 0.96 6 ! 23.9 0.1 3.2e-06 0.00026 10 38 .] 266 298 .. 259 298 .. 0.84 7 ! 20.4 0.6 4.1e-05 0.0033 5 38 .] 306 340 .] 302 340 .] 0.92 Alignments for each domain: == domain 1 score: 24.6 bits; conditional E-value: 1.9e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd sp|P62879|GBB2_HUMAN 48 RRTLRGHlAKIYAMHWGTDSRLLVSASQDGKLIIWD 83 689****999*************************9 PP == domain 2 score: 12.3 bits; conditional E-value: 0.015 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +v +a+ p+g+++a+G+ D+ + i+ sp|P62879|GBB2_HUMAN 99 WVMTCAYAPSGNFVACGGLDNICSIY 124 488889*****************998 PP == domain 3 score: 19.8 bits; conditional E-value: 6.4e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + ++++f +d++ ++s++ D t+ +Wd sp|P62879|GBB2_HUMAN 136 SRELPGHtGYLSCCRFLDDNQIITSSG-DTTCALWD 170 57899**666*************9999.*******9 PP == domain 4 score: 23.7 bits; conditional E-value: 3.7e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH ++v sl+ pdg+ ++sG D ++++Wd sp|P62879|GBB2_HUMAN 180 FAGHsGDVMSLSLAPDGRTFVSGACDASIKLWD 212 78**777****************77*******9 PP == domain 5 score: 28.7 bits; conditional E-value: 9.9e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +t+ GH s+++++af p+g +++GsdD t+r++d sp|P62879|GBB2_HUMAN 218 CRQTFIGHeSDINAVAFFPNGYAFTTGSDDATCRLFD 254 8899****999************************98 PP == domain 6 score: 23.9 bits; conditional E-value: 3.2e-06 S.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ss...vtslafspdgawlasGsdDgtvriWd 38 H + +ts+afs++g++l++G dD ++ iWd sp|P62879|GBB2_HUMAN 266 HdNIicgITSVAFSRSGRLLLAGYDDFNCNIWD 298 74336669************************9 PP == domain 7 score: 20.4 bits; conditional E-value: 4.1e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l GH + v++l + +dg +a+Gs+D ++iW+ sp|P62879|GBB2_HUMAN 306 GVLAGHdNRVSCLGVTDDGMAVATGSWDSFLKIWN 340 5788**888*************************8 PP >> tr|B4E3L0|B4E3L0_HUMAN WD40 repeat-containing protein SMU1 OS=Homo sapiens GN=SMU1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 0.0 3.2e-08 2.6e-06 5 38 .] 46 81 .. 42 81 .. 0.85 2 ! 22.1 0.0 1.2e-05 0.00099 13 38 .] 106 131 .. 91 131 .. 0.88 3 ! 28.5 0.1 1.1e-07 9.1e-06 1 36 [. 135 172 .. 135 173 .. 0.93 4 ! 34.4 0.1 1.5e-09 1.2e-07 1 38 [] 178 216 .. 178 216 .. 0.92 5 ? 6.3 0.1 1.2 94 3 34 .. 270 305 .. 268 309 .. 0.66 6 ! 19.8 0.0 6.5e-05 0.0053 1 38 [] 313 351 .. 313 351 .. 0.93 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 3.2e-08 EEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 r+++ G+ s+v + +fspdg++l++Gs Dg + +W+ tr|B4E3L0|B4E3L0_HUMAN 46 RHIKfGQkSHVECARFSPDGQYLVTGSVDGFIEVWN 81 5555577666*************************8 PP == domain 2 score: 22.1 bits; conditional E-value: 1.2e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v +++fs+d +la+G Dg++++W+ tr|B4E3L0|B4E3L0_HUMAN 106 VLCMCFSRDTEMLATGAQDGKIKVWK 131 99***********************6 PP == domain 3 score: 28.5 bits; conditional E-value: 1.1e-07 TEEEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 1 gqclrtlt.GH.ssvtslafspdgawlasGsdDgtvri 36 gqclr ++ +H ++vt+l+fs+d++ ++s+s D+t+ri tr|B4E3L0|B4E3L0_HUMAN 135 GQCLRRFErAHsKGVTCLSFSKDSSQILSASFDQTIRI 172 79*****55**999****************99*****9 PP == domain 4 score: 34.4 bits; conditional E-value: 1.5e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l++++GH s+v+ f +dg++++s+s Dgtv+iW+ tr|B4E3L0|B4E3L0_HUMAN 178 GKTLKEFRGHsSFVNEATFTQDGHYIISASSDGTVKIWN 216 6889******777*************99988*******8 PP == domain 5 score: 6.3 bits; conditional E-value: 1.2 EEEEEE.SS.SS...EEEEEEETTSSEEEEEETTSEE CS WD40 3 clrtlt.GH.ss...vtslafspdgawlasGsdDgtv 34 +r+++ G + v ++a sp g w+ + ++D + tr|B4E3L0|B4E3L0_HUMAN 270 IVRSFSsGKrEGgdfV-CCALSPRGEWIYCVGEDFVL 305 5666653333113447.999********987888665 PP == domain 6 score: 19.8 bits; conditional E-value: 6.5e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++ rtlt H ++v ++a +p+++++a+ s+Dg +++W+ tr|B4E3L0|B4E3L0_HUMAN 313 GKLERTLTVHeKDVIGIAHHPHQNLIATYSEDGLLKLWK 351 57789********99***********9989********6 PP >> sp|Q86TI4|WDR86_HUMAN WD repeat-containing protein 86 OS=Homo sapiens GN=WDR86 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.1 1.3e-06 0.00011 3 38 .] 7 43 .. 5 43 .. 0.91 2 ! 14.0 0.0 0.0042 0.34 1 38 [] 47 83 .. 47 83 .. 0.83 3 ! 23.1 0.0 5.9e-06 0.00048 1 38 [] 87 123 .. 87 123 .. 0.75 4 ! 17.1 0.0 0.00047 0.038 2 37 .. 128 178 .. 127 179 .. 0.79 5 ! 18.4 0.5 0.00018 0.014 2 38 .] 184 221 .. 183 221 .. 0.91 6 ! 16.7 0.0 0.00059 0.048 1 37 [. 225 260 .. 225 260 .. 0.78 7 ? 9.5 0.0 0.12 9.5 1 31 [. 265 294 .. 265 301 .. 0.71 8 ! 23.1 0.1 5.8e-06 0.00047 2 38 .] 306 341 .. 305 341 .. 0.87 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 1.3e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 lr++ H ++++ l+ spdg+ l++Gs+Dgt r+W+ sp|Q86TI4|WDR86_HUMAN 7 ALRVCADHrGGINWLSLSPDGQRLLTGSEDGTARLWS 43 5788889*999*************************5 PP == domain 2 score: 14.0 bits; conditional E-value: 0.0042 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqc l GH s vt ++ ++ a+ ++s D+t+r Wd sp|Q86TI4|WDR86_HUMAN 47 GQCCALLQGHeSYVTFCQLEDEAAF--TCSADCTIRRWD 83 6888899***888*98867777777..7999*******9 PP == domain 3 score: 23.1 bits; conditional E-value: 5.9e-06 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 gqcl++++GH+s v+ + + ++ +s+s+D+t r+W+ sp|Q86TI4|WDR86_HUMAN 87 GQCLQVYRGHTSiVNRILVANNQL--FSSSYDRTARVWS 123 79********55479994433333..46888*******5 PP == domain 4 score: 17.1 bits; conditional E-value: 0.00047 EEEEEEESS.SSEEEEEEETTSSE................EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw................lasGsdDgtvriW 37 q r+++GH ++v la + +w l++Gs Dgt ++W sp|Q86TI4|WDR86_HUMAN 128 QMSREFRGHrNCVLTLA--YSAPWdlpstpcaeeaaagglLVTGSTDGTAKVW 178 67899****99999994..23444667777788888888789*********** PP == domain 5 score: 18.4 bits; conditional E-value: 0.00018 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +tl+GH + v +l + g+ ++Gs D t+r Wd sp|Q86TI4|WDR86_HUMAN 184 CCHQTLRGHtGAVLCLVLDTPGHTAFTGSTDATIRAWD 221 68899****777*****999999999***********9 PP == domain 6 score: 16.7 bits; conditional E-value: 0.00059 TEEEEEEESS.SS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ss......vtslafspdgawlasGsdDgtvriW 37 g++lr+++ H +s v+ l + sGs D+tv+ W sp|Q86TI4|WDR86_HUMAN 225 GEQLRVFREHrGSviclelVNRL--------VYSGSADRTVKCW 260 5789******9885444444444........88*********** PP == domain 7 score: 9.5 bits; conditional E-value: 0.12 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETT CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdD 31 g+c+rt+t+H +v++l ++ l++Gs D sp|Q86TI4|WDR86_HUMAN 265 GECVRTFTAHrRNVSAL------KYhagtLFTGSGD 294 69********877****......5533333477656 PP == domain 8 score: 23.1 bits; conditional E-value: 5.8e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ r+++GH++ ++++ + +g+ l ++s Dg +r+Wd sp|Q86TI4|WDR86_HUMAN 306 ELRRVFRGHTFiINCI--QVHGQVLYTASHDGALRLWD 341 67799****6648***..889999999999*******9 PP >> sp|O43172-2|PRP4_HUMAN Isoform 2 of U4/U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens GN=PRPF4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.3 0.01 0.85 13 38 .] 233 258 .. 214 258 .. 0.78 2 ! 25.0 0.2 1.5e-06 0.00012 2 38 .] 263 308 .. 262 308 .. 0.92 3 ! 16.3 0.2 0.00082 0.066 3 38 .] 314 350 .. 312 350 .. 0.79 4 ? 11.0 0.0 0.039 3.2 5 38 .] 358 392 .. 354 392 .. 0.80 5 ! 35.0 0.1 9.8e-10 7.9e-08 1 38 [] 396 434 .. 396 434 .. 0.96 6 ! 17.8 0.0 0.00027 0.022 2 37 .. 439 476 .. 438 477 .. 0.83 7 ! 30.0 0.0 3.7e-08 3e-06 1 37 [. 481 518 .. 481 519 .. 0.94 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.01 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++ + fsp++++la++++ g +++W+ sp|O43172-2|PRP4_HUMAN 233 ISYCHFSPNSKMLATACWSGLCKLWS 258 54455********************5 PP == domain 2 score: 25.0 bits; conditional E-value: 1.5e-06 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 ++l+tl+GH ++v ++ f+p ++ las+ Dg+v++W+ sp|O43172-2|PRP4_HUMAN 263 NLLHTLRGHnTNVGAIVFHPKSTVsldpkdvnLASCAADGSVKLWS 308 789******766******************99****99*******5 PP == domain 3 score: 16.3 bits; conditional E-value: 0.00082 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++GH v + ++p+g++l +++ D++ r+Wd sp|O43172-2|PRP4_HUMAN 314 PVADIEGHtVRVARVMWHPSGRFLgTTCY-DRSWRLWD 350 5666789944466777*******966667.*******9 PP == domain 4 score: 11.0 bits; conditional E-value: 0.039 EEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 + +GH +v+++af++dg++ a +G+ D r+Wd sp|O43172-2|PRP4_HUMAN 358 LHQEGHsMGVYDIAFHQDGSL-AgTGGLDAFGRVWD 392 4558**555************.54889999999998 PP == domain 5 score: 35.0 bits; conditional E-value: 9.8e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c+ l+GH + ++++ fsp+g +a+Gs D+t+++Wd sp|O43172-2|PRP4_HUMAN 396 GRCIMFLEGHlKEIYGINFSPNGYHIATGSGDNTCKVWD 434 68999************************99*******9 PP == domain 6 score: 17.8 bits; conditional E-value: 0.00027 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 +c++t+ +H + vt+++ + +g++l++G +D+t +iW sp|O43172-2|PRP4_HUMAN 439 RCVYTIPAHqNLVTGVKfEPIHGNFLLTGAYDNTAKIW 476 79*******555****95555666689**99******* PP == domain 7 score: 30.0 bits; conditional E-value: 3.7e-08 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++l+tl GH + v +l+ s+dg+++a++s+D+t ++W sp|O43172-2|PRP4_HUMAN 481 WSPLKTLAGHeGKVMGLDISSDGQLIATCSYDRTFKLW 518 6799******777************************* PP >> sp|O43172|PRP4_HUMAN U4/U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens GN=PRPF4 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.3 0.01 0.85 13 38 .] 234 259 .. 215 259 .. 0.78 2 ! 25.0 0.2 1.5e-06 0.00012 2 38 .] 264 309 .. 263 309 .. 0.92 3 ! 16.3 0.2 0.00082 0.066 3 38 .] 315 351 .. 313 351 .. 0.79 4 ? 11.0 0.0 0.039 3.2 5 38 .] 359 393 .. 355 393 .. 0.80 5 ! 35.0 0.1 9.8e-10 8e-08 1 38 [] 397 435 .. 397 435 .. 0.96 6 ! 17.8 0.0 0.00027 0.022 2 37 .. 440 477 .. 439 478 .. 0.83 7 ! 30.0 0.0 3.7e-08 3e-06 1 37 [. 482 519 .. 482 520 .. 0.94 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.01 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++ + fsp++++la++++ g +++W+ sp|O43172|PRP4_HUMAN 234 ISYCHFSPNSKMLATACWSGLCKLWS 259 54455********************5 PP == domain 2 score: 25.0 bits; conditional E-value: 1.5e-06 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 ++l+tl+GH ++v ++ f+p ++ las+ Dg+v++W+ sp|O43172|PRP4_HUMAN 264 NLLHTLRGHnTNVGAIVFHPKSTVsldpkdvnLASCAADGSVKLWS 309 789******766******************99****99*******5 PP == domain 3 score: 16.3 bits; conditional E-value: 0.00082 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++GH v + ++p+g++l +++ D++ r+Wd sp|O43172|PRP4_HUMAN 315 PVADIEGHtVRVARVMWHPSGRFLgTTCY-DRSWRLWD 351 5666789944466777*******966667.*******9 PP == domain 4 score: 11.0 bits; conditional E-value: 0.039 EEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 + +GH +v+++af++dg++ a +G+ D r+Wd sp|O43172|PRP4_HUMAN 359 LHQEGHsMGVYDIAFHQDGSL-AgTGGLDAFGRVWD 393 4558**555************.54889999999998 PP == domain 5 score: 35.0 bits; conditional E-value: 9.8e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c+ l+GH + ++++ fsp+g +a+Gs D+t+++Wd sp|O43172|PRP4_HUMAN 397 GRCIMFLEGHlKEIYGINFSPNGYHIATGSGDNTCKVWD 435 68999************************99*******9 PP == domain 6 score: 17.8 bits; conditional E-value: 0.00027 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 +c++t+ +H + vt+++ + +g++l++G +D+t +iW sp|O43172|PRP4_HUMAN 440 RCVYTIPAHqNLVTGVKfEPIHGNFLLTGAYDNTAKIW 477 79*******555****95555666689**99******* PP == domain 7 score: 30.0 bits; conditional E-value: 3.7e-08 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++l+tl GH + v +l+ s+dg+++a++s+D+t ++W sp|O43172|PRP4_HUMAN 482 WSPLKTLAGHeGKVMGLDISSDGQLIATCSYDRTFKLW 519 6799******777************************* PP >> sp|Q9GZS3|WDR61_HUMAN WD repeat-containing protein 61 OS=Homo sapiens GN=WDR61 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.1 0.0093 0.76 9 38 .] 14 48 .. 6 48 .. 0.79 2 ! 19.0 0.4 0.00011 0.0092 3 38 .] 56 92 .. 54 92 .. 0.91 3 ? 9.9 0.0 0.089 7.2 14 29 .. 110 125 .. 96 131 .. 0.81 4 ! 20.1 0.0 5.1e-05 0.0041 11 38 .] 149 176 .. 138 176 .. 0.84 5 ! 38.0 0.0 1.2e-10 9.4e-09 1 38 [] 180 218 .. 180 218 .. 0.96 6 ! 30.7 1.5 2.3e-08 1.9e-06 5 38 .] 226 260 .. 222 260 .. 0.92 7 ! 18.9 0.7 0.00012 0.0098 2 38 .] 265 302 .. 264 302 .. 0.92 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0093 SS.SSEEEEEEETTSSE..........EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..........lasGsdDgtvriWd 38 +H + ++s+a w +++Gs D v++W+ sp|Q9GZS3|WDR61_HUMAN 14 AHdDAIWSVA------WgtnkkensetVVTGSLDDLVKVWK 48 89555****5......5555555999999***********6 PP == domain 2 score: 19.0 bits; conditional E-value: 0.00011 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++l+GH +v s++ s+ + as+s D ++r+Wd sp|Q9GZS3|WDR61_HUMAN 56 LQWSLEGHqLGVVSVDISHTLPIAASSSLDAHIRLWD 92 6899****76699**********99999********9 PP == domain 3 score: 9.9 bits; conditional E-value: 0.089 EEEEEETTSSEEEEEE CS WD40 14 tslafspdgawlasGs 29 + lafspd+++la+G+ sp|Q9GZS3|WDR61_HUMAN 110 WTLAFSPDSQYLATGT 125 7899**********95 PP == domain 4 score: 20.1 bits; conditional E-value: 5.1e-05 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 +++ s+a+spdg++lasG Dg + i+d sp|Q9GZS3|WDR61_HUMAN 149 KFILSIAYSPDGKYLASGAIDGIINIFD 176 5799**********************98 PP == domain 5 score: 38.0 bits; conditional E-value: 1.2e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l+tl+GH +++sl fspd+++l+++sdDg ++i+d sp|Q9GZS3|WDR61_HUMAN 180 GKLLHTLEGHaMPIRSLTFSPDSQLLVTASDDGYIKIYD 218 689*******888*************************8 PP == domain 6 score: 30.7 bits; conditional E-value: 2.3e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tl+GH s+v +af+pd + ++s+s D++v++Wd sp|Q9GZS3|WDR61_HUMAN 226 GTLSGHaSWVLNVAFCPDDTHFVSSSSDKSVKVWD 260 79****999*************99877*******9 PP == domain 7 score: 18.9 bits; conditional E-value: 0.00012 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c++t+ H + v++++++ +g+ ++s +dD+ ++i+d sp|Q9GZS3|WDR61_HUMAN 265 TCVHTFFDHqDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302 79***999*666**************9999******98 PP >> tr|K7EN33|K7EN33_HUMAN Notchless protein homolog 1 (Fragment) OS=Homo sapiens GN=NLE1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 0.5 0.26 21 28 38 .] 2 12 .. 2 12 .. 0.91 2 ! 31.9 0.2 9.7e-09 7.9e-07 1 37 [. 16 52 .. 16 53 .. 0.90 3 ? 11.3 0.3 0.03 2.4 4 38 .] 60 137 .. 57 137 .. 0.86 4 ! 30.2 0.0 3.4e-08 2.7e-06 2 38 .] 143 180 .. 142 180 .. 0.91 5 ! 33.7 0.1 2.6e-09 2.1e-07 4 38 .] 226 261 .. 223 261 .. 0.94 6 ! 34.5 0.0 1.5e-09 1.2e-07 6 37 .. 270 302 .. 265 303 .. 0.90 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.26 EETTSEEEEEE CS WD40 28 GsdDgtvriWd 38 +s+Dg+vriWd tr|K7EN33|K7EN33_HUMAN 2 SSKDGSVRIWD 12 589*******9 PP == domain 2 score: 31.9 bits; conditional E-value: 9.7e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+c r+ltGH +svt+l++ dg + s+s D+t+++W tr|K7EN33|K7EN33_HUMAN 16 GRCERILTGHtQSVTCLRWGGDGLL-YSASQDRTIKVW 52 6899******999****88888877.89********** PP == domain 3 score: 11.3 bits; conditional E-value: 0.03 EEEEESS.SSEEEEEEETTSSE..........................................EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw..........................................lasGsdDgtvriWd 38 rtl GH +v+ +a s d a+ l+sGsdD t+ +W+ tr|K7EN33|K7EN33_HUMAN 60 CRTLQGHgHWVNTMALSTDYALrtgafepaeasvnpqdlqgslqelkeralsrynlvrgqgperLVSGSDDFTLFLWS 137 588999944599999888888888888999999999999999999999999999999999999999***********5 PP == domain 4 score: 30.2 bits; conditional E-value: 3.4e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+ tGH+ ++ + fspd++ +as+s D+++++Wd tr|K7EN33|K7EN33_HUMAN 143 KPLTRMTGHQAlINQVLFSPDSRIVASASFDKSIKLWD 180 6788899**6679***************99*******9 PP == domain 5 score: 33.7 bits; conditional E-value: 2.6e-09 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l+GH v+ +a+s d+++l+sGs D t+++Wd tr|K7EN33|K7EN33_HUMAN 226 LASLRGHvAAVYQIAWSADSRLLVSGSSDSTLKVWD 261 789****999****************99*******9 PP == domain 6 score: 34.5 bits; conditional E-value: 1.5e-09 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH + v+++++spdg+ +asG++D+ +riW tr|K7EN33|K7EN33_HUMAN 270 DLPGHaDEVYAVDWSPDGQRVASGGKDKCLRIW 302 588**777************************* PP >> sp|Q6ZMY6-2|WDR88_HUMAN Isoform 2 of WD repeat-containing protein 88 OS=Homo sapiens GN=WDR88 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 0.8 9.2e-07 7.5e-05 4 38 .] 95 130 .. 93 130 .. 0.89 2 ? 11.0 0.0 0.039 3.1 10 38 .] 142 173 .. 134 173 .. 0.72 3 ! 13.8 0.1 0.0049 0.4 13 36 .. 189 213 .. 178 215 .. 0.83 4 ! 26.3 1.4 5.8e-07 4.7e-05 6 38 .] 224 258 .. 219 258 .. 0.84 5 ! 26.2 1.0 6.2e-07 5e-05 4 38 .] 266 301 .. 263 301 .. 0.90 6 ! 27.6 0.4 2.2e-07 1.8e-05 2 38 .] 312 349 .. 311 349 .. 0.93 7 ! 30.6 0.1 2.4e-08 2e-06 6 38 .] 358 391 .. 354 391 .. 0.92 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 9.2e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH v+ + f+ d + l+sGs+D+tv++Wd sp|Q6ZMY6-2|WDR88_HUMAN 95 FKILSGHeHAVSTCHFCVDDTKLLSGSYDCTVKLWD 130 6899***555*8888999*****************9 PP == domain 2 score: 11.0 bits; conditional E-value: 0.039 S..SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H..ss.vtslafspdgawlasGsdDgtvriWd 38 H + v ++ d++ ++++s+D+tvr Wd sp|Q6ZMY6-2|WDR88_HUMAN 142 HrpKApVVECSITGDSSRVIAASYDKTVRAWD 173 644335656666888888888999*******9 PP == domain 3 score: 13.8 bits; conditional E-value: 0.0049 EEEEEEETTSSEEEEEET.TSEEEE CS WD40 13 vtslafspdgawlasGsd.Dgtvri 36 + s++fspdg++++sG d D+ + i sp|Q6ZMY6-2|WDR88_HUMAN 189 IVSCKFSPDGKYVVSGFDvDHGICI 213 789*************644987766 PP == domain 4 score: 26.3 bits; conditional E-value: 5.8e-07 EEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH..ssvtslafspdgawlasGsdDgtvriWd 38 +++ H s+ts++f+pd++ +as s D+ ++iWd sp|Q6ZMY6-2|WDR88_HUMAN 224 VIKDHhtRSITSCCFDPDSQRVASVSLDRCIKIWD 258 556665555**************99*********9 PP == domain 5 score: 26.2 bits; conditional E-value: 6.2e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++ ++H + ++ ++f +g++l+++s+D++++iW+ sp|Q6ZMY6-2|WDR88_HUMAN 266 LTITKAHsNAISNCCFTFSGHFLCTSSWDKNLKIWN 301 66778**888*9999********************8 PP == domain 6 score: 27.6 bits; conditional E-value: 2.2e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c++ GH +sv+s+ f +d+++l+sG+ D+tv iWd sp|Q6ZMY6-2|WDR88_HUMAN 312 ACVTLMQGHeGSVSSCHFARDSSFLISGGFDRTVAIWD 349 6788889**999****************99*******9 PP == domain 7 score: 30.6 bits; conditional E-value: 2.4e-08 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH ++v ++a s +++w++s+s+D+t r+W+ sp|Q6ZMY6-2|WDR88_HUMAN 358 SLKGHnDWVMDVAISNNKKWILSASKDRTMRLWN 391 789**555*************************8 PP >> sp|P16520|GBB3_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 OS=Homo sapiens GN=GNB3 PE=1 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 1.7e-06 0.00014 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 12.9 0.0 0.0098 0.79 12 38 .] 99 125 .. 86 125 .. 0.86 3 ! 19.0 0.4 0.00011 0.0093 4 38 .] 136 170 .. 133 170 .. 0.90 4 ! 19.8 0.1 6.4e-05 0.0052 2 38 .] 175 212 .. 174 212 .. 0.90 5 ! 33.1 0.1 3.9e-09 3.2e-07 1 38 [] 216 254 .. 216 254 .. 0.96 6 ! 19.2 0.1 0.0001 0.0081 10 38 .] 266 298 .. 259 298 .. 0.83 7 ! 23.3 0.4 4.9e-06 0.0004 4 38 .] 305 340 .] 302 340 .] 0.93 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 1.7e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ +Wd sp|P16520|GBB3_HUMAN 48 RRTLRGHlAKIYAMHWATDSKLLVSASQDGKLIVWD 83 689****999*************************9 PP == domain 2 score: 12.9 bits; conditional E-value: 0.0098 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ sp|P16520|GBB3_HUMAN 99 WVMTCAYAPSGNFVACGGLDNMCSIYN 125 488889******************997 PP == domain 3 score: 19.0 bits; conditional E-value: 0.00011 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l++H + ++++f +d++ ++s++ D t+ +Wd sp|P16520|GBB3_HUMAN 136 SRELSAHtGYLSCCRFLDDNNIVTSSG-DTTCALWD 170 6899***666*************9989.*******9 PP == domain 4 score: 19.8 bits; conditional E-value: 6.4e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+ +++ GH ++ sla+spd ++++sG D + ++Wd sp|P16520|GBB3_HUMAN 175 QQKTVFVGHtGDCMSLAVSPDFNLFISGACDASAKLWD 212 6677899**88899**************77*******9 PP == domain 5 score: 33.1 bits; conditional E-value: 3.9e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c +t+tGH s++++++f p+g +++GsdD ++r++d sp|P16520|GBB3_HUMAN 216 GTCRQTFTGHeSDINAICFFPNGEAICTGSDDASCRLFD 254 6799******999************************98 PP == domain 6 score: 19.2 bits; conditional E-value: 0.0001 SSS....EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss....vtslafspdgawlasGsdDgtvriWd 38 H s +ts+afs +g++l++G dD ++ +Wd sp|P16520|GBB3_HUMAN 266 HESiicgITSVAFSLSGRLLFAGYDDFNCNVWD 298 62335559************************9 PP == domain 7 score: 23.3 bits; conditional E-value: 4.9e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++l+GH + v++l + dg +a+Gs+D ++iW+ sp|P16520|GBB3_HUMAN 305 VGILSGHdNRVSCLGVTADGMAVATGSWDSFLKIWN 340 789****888*************************8 PP >> tr|J3KPE3|J3KPE3_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 0.1 3.1e-06 0.00025 4 38 .] 8 47 .. 5 47 .. 0.76 2 ! 36.4 0.2 3.6e-10 2.9e-08 3 38 .] 53 89 .. 51 89 .. 0.93 3 ! 24.6 1.0 1.9e-06 0.00015 9 38 .] 102 134 .. 92 134 .. 0.83 4 ! 24.2 0.2 2.5e-06 0.00021 7 38 .] 144 176 .. 138 176 .. 0.86 5 ! 23.1 0.1 6e-06 0.00049 2 38 .] 181 216 .. 180 216 .. 0.87 6 ! 18.7 0.0 0.00015 0.012 13 37 .. 242 266 .. 229 267 .. 0.90 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 3.1e-06 EEEEESS.SSEEEEE.EETTSSEEEE...EETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlas...GsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s Gs+Dgt+r+Wd tr|J3KPE3|J3KPE3_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSasrGSWDGTLRLWD 47 5799***666****986666666666335689*******9 PP == domain 2 score: 36.4 bits; conditional E-value: 3.6e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|J3KPE3|J3KPE3_HUMAN 53 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 89 678899******************************8 PP == domain 3 score: 24.6 bits; conditional E-value: 1.9e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|J3KPE3|J3KPE3_HUMAN 102 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 134 79666*************989***********8 PP == domain 4 score: 24.2 bits; conditional E-value: 2.5e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd tr|J3KPE3|J3KPE3_HUMAN 144 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 176 3499666*************************9 PP == domain 5 score: 23.1 bits; conditional E-value: 6e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+tl+G + +++l+fsp+ wl++++ ++++iWd tr|J3KPE3|J3KPE3_HUMAN 181 KHLYTLDGG-DiINALCFSPNRYWLCAAT-GPSIKIWD 216 778888887.448************9888.*******9 PP == domain 6 score: 18.7 bits; conditional E-value: 0.00015 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 tsla+s dg+ l++G D+ vr+W tr|J3KPE3|J3KPE3_HUMAN 242 CTSLAWSADGQTLFAGYTDNLVRVW 266 59**************88******* PP >> sp|Q6ZMY6|WDR88_HUMAN WD repeat-containing protein 88 OS=Homo sapiens GN=WDR88 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 0.8 1.1e-06 8.5e-05 4 38 .] 95 130 .. 93 130 .. 0.89 2 ? 10.8 0.0 0.044 3.6 10 38 .] 142 173 .. 134 173 .. 0.72 3 ! 13.7 0.1 0.0056 0.45 13 36 .. 189 213 .. 178 215 .. 0.83 4 ! 26.1 1.4 6.6e-07 5.3e-05 6 38 .] 224 258 .. 219 258 .. 0.84 5 ! 26.0 1.0 7.1e-07 5.7e-05 4 38 .] 266 301 .. 263 301 .. 0.90 6 ! 27.4 0.4 2.5e-07 2e-05 2 38 .] 312 349 .. 311 349 .. 0.93 7 ! 30.5 0.1 2.8e-08 2.2e-06 6 38 .] 358 391 .. 354 391 .. 0.92 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 1.1e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH v+ + f+ d + l+sGs+D+tv++Wd sp|Q6ZMY6|WDR88_HUMAN 95 FKILSGHeHAVSTCHFCVDDTKLLSGSYDCTVKLWD 130 6899***555*8888999*****************9 PP == domain 2 score: 10.8 bits; conditional E-value: 0.044 S..SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H..ss.vtslafspdgawlasGsdDgtvriWd 38 H + v ++ d++ ++++s+D+tvr Wd sp|Q6ZMY6|WDR88_HUMAN 142 HrpKApVVECSITGDSSRVIAASYDKTVRAWD 173 644334656666888888888999*******9 PP == domain 3 score: 13.7 bits; conditional E-value: 0.0056 EEEEEEETTSSEEEEEET.TSEEEE CS WD40 13 vtslafspdgawlasGsd.Dgtvri 36 + s++fspdg++++sG d D+ + i sp|Q6ZMY6|WDR88_HUMAN 189 IVSCKFSPDGKYVVSGFDvDHGICI 213 789*************644987766 PP == domain 4 score: 26.1 bits; conditional E-value: 6.6e-07 EEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH..ssvtslafspdgawlasGsdDgtvriWd 38 +++ H s+ts++f+pd++ +as s D+ ++iWd sp|Q6ZMY6|WDR88_HUMAN 224 VIKDHhtRSITSCCFDPDSQRVASVSLDRCIKIWD 258 556665555**************99*********9 PP == domain 5 score: 26.0 bits; conditional E-value: 7.1e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++ ++H + ++ ++f +g++l+++s+D++++iW+ sp|Q6ZMY6|WDR88_HUMAN 266 LTITKAHsNAISNCCFTFSGHFLCTSSWDKNLKIWN 301 66778**888*9999********************8 PP == domain 6 score: 27.4 bits; conditional E-value: 2.5e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c++ GH +sv+s+ f +d+++l+sG+ D+tv iWd sp|Q6ZMY6|WDR88_HUMAN 312 ACVTLMQGHeGSVSSCHFARDSSFLISGGFDRTVAIWD 349 6788889**999****************99*******9 PP == domain 7 score: 30.5 bits; conditional E-value: 2.8e-08 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH ++v ++a s +++w++s+s+D+t r+W+ sp|Q6ZMY6|WDR88_HUMAN 358 SLKGHnDWVMDVAISNNKKWILSASKDRTMRLWN 391 789**555*************************8 PP >> tr|H3BPD8|H3BPD8_HUMAN Katanin p80 WD40 repeat-containing subunit B1 (Fragment) OS=Homo sapiens GN=KATNB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 0.0015 0.12 8 38 .] 21 53 .. 16 53 .. 0.87 2 ! 26.5 0.0 4.8e-07 3.9e-05 2 38 .] 58 95 .. 57 95 .. 0.93 3 ! 38.5 0.0 7.8e-11 6.3e-09 3 38 .] 101 137 .. 99 137 .. 0.93 4 ! 48.0 0.2 7.7e-14 6.3e-12 3 38 .] 143 179 .. 141 179 .. 0.93 5 ? 6.2 0.0 1.3 1e+02 2 22 .. 184 205 .. 183 208 .] 0.82 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 0.0015 ESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +H s+v+sl +g++la+G+dD+ v +W+ tr|H3BPD8|H3BPD8_HUMAN 21 VAHaSNVSSLVlGKASGRLLATGGDDCRVNLWS 53 57977799999999999***************5 PP == domain 2 score: 26.5 bits; conditional E-value: 4.8e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ +ltGH s+v s++ + ++++Gs g++r+Wd tr|H3BPD8|H3BPD8_HUMAN 58 NCIMSLTGHtSPVESVRLNTPEELIVAGSQSGSIRVWD 95 79*******999****98888888999**********9 PP == domain 3 score: 38.5 bits; conditional E-value: 7.8e-11 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 lrtl GH +++sl+f+p+g ++asGs D ++++Wd tr|H3BPD8|H3BPD8_HUMAN 101 ILRTLMGHkANICSLDFHPYGEFVASGSQDTNIKLWD 137 689999**666*************************9 PP == domain 4 score: 48.0 bits; conditional E-value: 7.7e-14 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c+ ++GH + v++l+fspdg+wlas+ dD+tv++Wd tr|H3BPD8|H3BPD8_HUMAN 143 CVFRYRGHsQAVRCLRFSPDGKWLASAADDHTVKLWD 179 8899****666****************9********9 PP == domain 5 score: 6.2 bits; conditional E-value: 1.3 EEEEEEESS.SSEEEEEEETTS CS WD40 2 qclrtltGH.ssvtslafspdg 22 + + ++ GH ++v+ + f+p+ tr|H3BPD8|H3BPD8_HUMAN 184 KMMSEFPGHtGPVNVVEFHPNE 205 567889***888********96 PP >> sp|Q2TAY7|SMU1_HUMAN WD40 repeat-containing protein SMU1 OS=Homo sapiens GN=SMU1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.6 0.0 5.2e-08 4.2e-06 5 38 .] 207 242 .. 203 242 .. 0.85 2 ! 21.4 0.0 2e-05 0.0016 13 38 .] 267 292 .. 252 292 .. 0.88 3 ! 27.8 0.1 1.8e-07 1.5e-05 1 36 [. 296 333 .. 296 334 .. 0.93 4 ! 33.7 0.1 2.5e-09 2.1e-07 1 38 [] 339 377 .. 339 377 .. 0.92 5 ? 5.6 0.1 1.9 1.5e+02 3 34 .. 431 466 .. 429 470 .. 0.66 6 ! 19.1 0.0 0.00011 0.0087 1 38 [] 474 512 .. 474 512 .. 0.93 Alignments for each domain: == domain 1 score: 29.6 bits; conditional E-value: 5.2e-08 EEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 r+++ G+ s+v + +fspdg++l++Gs Dg + +W+ sp|Q2TAY7|SMU1_HUMAN 207 RHIKfGQkSHVECARFSPDGQYLVTGSVDGFIEVWN 242 5555577666*************************8 PP == domain 2 score: 21.4 bits; conditional E-value: 2e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v +++fs+d +la+G Dg++++W+ sp|Q2TAY7|SMU1_HUMAN 267 VLCMCFSRDTEMLATGAQDGKIKVWK 292 99***********************6 PP == domain 3 score: 27.8 bits; conditional E-value: 1.8e-07 TEEEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 1 gqclrtlt.GH.ssvtslafspdgawlasGsdDgtvri 36 gqclr ++ +H ++vt+l+fs+d++ ++s+s D+t+ri sp|Q2TAY7|SMU1_HUMAN 296 GQCLRRFErAHsKGVTCLSFSKDSSQILSASFDQTIRI 333 79*****55**999****************99*****9 PP == domain 4 score: 33.7 bits; conditional E-value: 2.5e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l++++GH s+v+ f +dg++++s+s Dgtv+iW+ sp|Q2TAY7|SMU1_HUMAN 339 GKTLKEFRGHsSFVNEATFTQDGHYIISASSDGTVKIWN 377 6889******777*************99988*******8 PP == domain 5 score: 5.6 bits; conditional E-value: 1.9 EEEEEE.SS.SS...EEEEEEETTSSEEEEEETTSEE CS WD40 3 clrtlt.GH.ss...vtslafspdgawlasGsdDgtv 34 +r+++ G + v ++a sp g w+ + ++D + sp|Q2TAY7|SMU1_HUMAN 431 IVRSFSsGKrEGgdfV-CCALSPRGEWIYCVGEDFVL 466 5666643333113447.999********977888665 PP == domain 6 score: 19.1 bits; conditional E-value: 0.00011 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++ rtlt H ++v ++a +p+++++a+ s+Dg +++W+ sp|Q2TAY7|SMU1_HUMAN 474 GKLERTLTVHeKDVIGIAHHPHQNLIATYSEDGLLKLWK 512 57789********99***********9989********6 PP >> sp|O43660-2|PLRG1_HUMAN Isoform 2 of Pleiotropic regulator 1 OS=Homo sapiens GN=PLRG1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.9 0.6 1.2e-10 9.7e-09 2 38 .] 186 223 .. 185 223 .. 0.94 2 ! 23.9 0.1 3.2e-06 0.00026 2 38 .] 228 265 .. 227 265 .. 0.93 3 ! 25.7 0.5 8.5e-07 6.9e-05 2 38 .] 270 307 .. 269 307 .. 0.95 4 ! 23.7 0.1 3.8e-06 0.00031 4 38 .] 314 349 .. 311 349 .. 0.77 5 ? 7.5 0.0 0.49 40 5 37 .. 357 389 .. 353 390 .. 0.86 6 ! 20.0 0.3 5.6e-05 0.0046 3 38 .] 396 431 .. 394 431 .. 0.88 7 ? 7.6 0.0 0.47 38 11 37 .. 454 480 .. 444 481 .. 0.85 Alignments for each domain: == domain 1 score: 37.9 bits; conditional E-value: 1.2e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+++GH ++v+++a+ p ++w+++Gs D+t++iWd sp|O43660-2|PLRG1_HUMAN 186 KLYRVISGHlGWVRCIAVEPGNQWFVTGSADRTIKIWD 223 6678999******************************9 PP == domain 2 score: 23.9 bits; conditional E-value: 3.2e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +ltGH s v+++ +s +++l+s+++D+ v+ Wd sp|O43660-2|PLRG1_HUMAN 228 KLKLSLTGHiSTVRGVIVSTRSPYLFSCGEDKQVKCWD 265 566799****99*************************9 PP == domain 3 score: 25.7 bits; conditional E-value: 8.5e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r++ GH s v++l+ +p + l+++s+D t riWd sp|O43660-2|PLRG1_HUMAN 270 KVIRHYHGHlSAVYGLDLHPTIDVLVTCSRDSTARIWD 307 5689*********************************9 PP == domain 4 score: 23.7 bits; conditional E-value: 3.8e-06 EEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 ++tl+GH + v+++ + +++Gs D t+r+Wd sp|O43660-2|PLRG1_HUMAN 314 VHTLSGHtNAvatVRCQ---AAEPQIITGSHDTTIRLWD 349 8******8885555666...44444789*99*******9 PP == domain 5 score: 7.5 bits; conditional E-value: 0.49 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 tlt H +sv+++ +p + +asGs +++ W sp|O43660-2|PLRG1_HUMAN 357 VTLTNHkKSVRAVVLHPRHYTFASGS-PDNIKQW 389 5899**999*****************.8888888 PP == domain 6 score: 20.0 bits; conditional E-value: 5.6e-05 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ l+GH+ ++ l +++dg ++ sG d+gt ++Wd sp|O43660-2|PLRG1_HUMAN 396 FIQNLSGHNAiINTLTVNSDGVLV-SGADNGTMHLWD 431 57889***7757***********7.8*9********9 PP == domain 7 score: 7.6 bits; conditional E-value: 0.47 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 s++ ++af+++ + l+++ D+t++++ sp|O43660-2|PLRG1_HUMAN 454 SGIFACAFDQSESRLLTAEADKTIKVY 480 45999*************77*****98 PP >> tr|G3V5X7|G3V5X7_HUMAN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphata # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 7.7 6.2e+02 14 36 .. 1572 1594 .. 1557 1596 .. 0.87 2 ? 5.4 0.1 2.3 1.9e+02 8 38 .] 1608 1637 .. 1600 1637 .. 0.82 3 ? 11.8 0.1 0.021 1.7 8 38 .] 1648 1679 .. 1641 1679 .. 0.85 4 ? 12.5 0.0 0.013 1.1 10 36 .. 1689 1718 .. 1683 1720 .. 0.81 5 ? 6.6 0.0 0.96 78 7 38 .] 1772 1804 .. 1766 1804 .. 0.75 6 ? 4.0 0.0 6.4 5.2e+02 7 32 .. 1810 1842 .. 1806 1847 .. 0.71 7 ? 3.5 0.0 8.8 7.1e+02 15 37 .. 1913 1929 .. 1899 1929 .. 0.83 8 ! 26.8 0.2 3.8e-07 3.1e-05 3 38 .] 1945 1981 .. 1943 1981 .. 0.95 9 ! 15.3 3.4 0.0017 0.14 4 38 .] 1991 2026 .. 1989 2026 .. 0.86 10 ! 12.9 0.0 0.0099 0.8 2 38 .] 2031 2066 .. 2030 2066 .. 0.72 11 ? 3.4 0.0 9.8 8e+02 4 37 .. 2072 2115 .. 2069 2116 .. 0.80 12 ! 19.1 0.0 0.0001 0.0084 4 37 .. 2123 2157 .. 2120 2158 .. 0.91 13 ? 5.8 0.0 1.7 1.3e+02 12 37 .. 2174 2199 .. 2166 2200 .. 0.79 14 ? 8.4 0.0 0.26 21 10 37 .. 2446 2472 .. 2438 2473 .. 0.77 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 7.7 EEEEEETTSSEEEEEETTSEEEE CS WD40 14 tslafspdgawlasGsdDgtvri 36 t++afs +g+ a G+ +gtv++ tr|G3V5X7|G3V5X7_HUMAN 1572 TAVAFSTNGQRAAVGTANGTVYL 1594 89**********9**99***986 PP == domain 2 score: 5.4 bits; conditional E-value: 2.3 ESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriWd 38 +G ++++++ f +d ++++++ Dg + +Wd tr|G3V5X7|G3V5X7_HUMAN 1608 SGCDGISACLFLSDDTLFLTAF-DGLLELWD 1637 55556888889999999999**.*******9 PP == domain 3 score: 11.8 bits; conditional E-value: 0.021 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 ++H+ +t+++ spd ++la+ + g +++Wd tr|G3V5X7|G3V5X7_HUMAN 1648 KAHQYqITGCCLSPDCRLLATVCLGGCLKLWD 1679 689446**************9999*******9 PP == domain 4 score: 12.5 bits; conditional E-value: 0.013 S...SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 10 H...ssvtslafspdgawlasGsdDgtvri 36 H +s +++af+p+g+ +a+Gs+ g++ + tr|G3V5X7|G3V5X7_HUMAN 1689 HtypKSLNCVAFHPEGQVIATGSWAGSISF 1718 4334569****************9888865 PP == domain 5 score: 6.6 bits; conditional E-value: 0.96 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +H ++v + f + g l+++++Dg+v +W+ tr|G3V5X7|G3V5X7_HUMAN 1772 FPAHhGFVAAALFLHAGCQLLTAGEDGKVQVWS 1804 6778677865557777777889999*******5 PP == domain 6 score: 4.0 bits; conditional E-value: 6.4 EESS.SS.....EEEEEEETTSSEEEEEET.TS CS WD40 7 ltGH.ss.....vtslafspdgawlasGsd.Dg 32 +GH +s s+a spdg+ +a G + Dg tr|G3V5X7|G3V5X7_HUMAN 1810 PRGHlGSlslspALSVALSPDGDRVAVGYRaDG 1842 57888775544434888*********9964255 PP == domain 7 score: 3.5 bits; conditional E-value: 8.8 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 s + +las+s+D tv +W tr|G3V5X7|G3V5X7_HUMAN 1913 S------QELLASASEDFTVQLW 1929 3......4889************ PP == domain 8 score: 26.8 bits; conditional E-value: 3.8e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++l+GH ++v++++fs dg la+G++D+++ Wd tr|G3V5X7|G3V5X7_HUMAN 1945 CGTELRGHeGPVSCCSFSTDGGSLATGGRDRSLLCWD 1981 7789****999*************************9 PP == domain 9 score: 15.3 bits; conditional E-value: 0.0017 EEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ H ++vt++a+ +d+ +++++s Dg+v +Wd tr|G3V5X7|G3V5X7_HUMAN 1991 IHSFPaCHrDWVTGCAWTKDNLLISCSS-DGSVGLWD 2026 67776589889************97666.*******9 PP == domain 10 score: 12.9 bits; conditional E-value: 0.0099 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q l+ + GH s v+++ ++s s+Dgt+++Wd tr|G3V5X7|G3V5X7_HUMAN 2031 QRLGQFLGHqSAVSAV--AAVEEHVVSVSRDGTLKVWD 2066 6678899**7777777..222333778899*******9 PP == domain 11 score: 3.4 bits; conditional E-value: 9.8 EEEEESS.SSEEEEE........EETTSSEEE.EEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla........fspdgawla.sGsdDgtvriW 37 l+++ +H ++++++a +p + +l+ + + Dg r+W tr|G3V5X7|G3V5X7_HUMAN 2072 LTSIPAHsGPISHCAaamepraaGQPGSELLVvTVGLDGATRLW 2115 677889*777*666669******99999998635577******* PP == domain 12 score: 19.1 bits; conditional E-value: 0.0001 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++tl GH ++v++ a+s + +++++s+Dg+vr+W tr|G3V5X7|G3V5X7_HUMAN 2123 THTLLGHsGPVRAAAVSETSGLMLTASEDGSVRLW 2157 68999**777************************* PP == domain 13 score: 5.8 bits; conditional E-value: 1.7 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 vt++a+ pdg++ +sG g + +W tr|G3V5X7|G3V5X7_HUMAN 2174 AVTAVAWAPDGSMAVSGNQAGELILW 2199 39***********9999766666666 PP == domain 14 score: 8.4 bits; conditional E-value: 0.26 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H +svt+l + +l+++s+D+ v++W tr|G3V5X7|G3V5X7_HUMAN 2446 HsGSVTAL--HVLPELLVTASKDRDVKLW 2472 75569999..44444589*********** PP >> tr|A8MW61|A8MW61_HUMAN Pleiotropic regulator 1 OS=Homo sapiens GN=PLRG1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.9 0.6 1.2e-10 9.9e-09 2 38 .] 195 232 .. 194 232 .. 0.94 2 ! 23.9 0.1 3.3e-06 0.00027 2 38 .] 237 274 .. 236 274 .. 0.93 3 ! 25.7 0.5 8.7e-07 7.1e-05 2 38 .] 279 316 .. 278 316 .. 0.95 4 ! 23.6 0.1 3.9e-06 0.00032 4 38 .] 323 358 .. 320 358 .. 0.77 5 ? 7.5 0.0 0.5 41 5 37 .. 366 398 .. 362 399 .. 0.86 6 ! 19.9 0.3 5.8e-05 0.0047 3 38 .] 405 440 .. 403 440 .. 0.88 7 ? 7.5 0.0 0.48 39 11 37 .. 463 489 .. 453 490 .. 0.85 Alignments for each domain: == domain 1 score: 37.9 bits; conditional E-value: 1.2e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+++GH ++v+++a+ p ++w+++Gs D+t++iWd tr|A8MW61|A8MW61_HUMAN 195 KLYRVISGHlGWVRCIAVEPGNQWFVTGSADRTIKIWD 232 6678999******************************9 PP == domain 2 score: 23.9 bits; conditional E-value: 3.3e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +ltGH s v+++ +s +++l+s+++D+ v+ Wd tr|A8MW61|A8MW61_HUMAN 237 KLKLSLTGHiSTVRGVIVSTRSPYLFSCGEDKQVKCWD 274 566799****99*************************9 PP == domain 3 score: 25.7 bits; conditional E-value: 8.7e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r++ GH s v++l+ +p + l+++s+D t riWd tr|A8MW61|A8MW61_HUMAN 279 KVIRHYHGHlSAVYGLDLHPTIDVLVTCSRDSTARIWD 316 5689*********************************9 PP == domain 4 score: 23.6 bits; conditional E-value: 3.9e-06 EEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 ++tl+GH + v+++ + +++Gs D t+r+Wd tr|A8MW61|A8MW61_HUMAN 323 VHTLSGHtNAvatVRCQ---AAEPQIITGSHDTTIRLWD 358 8******8885555666...44444789*99*******9 PP == domain 5 score: 7.5 bits; conditional E-value: 0.5 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 tlt H +sv+++ +p + +asGs +++ W tr|A8MW61|A8MW61_HUMAN 366 VTLTNHkKSVRAVVLHPRHYTFASGS-PDNIKQW 398 5899**999*****************.8888888 PP == domain 6 score: 19.9 bits; conditional E-value: 5.8e-05 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ l+GH+ ++ l +++dg ++ sG d+gt ++Wd tr|A8MW61|A8MW61_HUMAN 405 FIQNLSGHNAiINTLTVNSDGVLV-SGADNGTMHLWD 440 57889***7757***********7.8*9********9 PP == domain 7 score: 7.5 bits; conditional E-value: 0.48 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 s++ ++af+++ + l+++ D+t++++ tr|A8MW61|A8MW61_HUMAN 463 SGIFACAFDQSESRLLTAEADKTIKVY 489 45999*************77*****98 PP >> sp|O43660|PLRG1_HUMAN Pleiotropic regulator 1 OS=Homo sapiens GN=PLRG1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.9 0.6 1.2e-10 9.9e-09 2 38 .] 195 232 .. 194 232 .. 0.94 2 ! 23.9 0.1 3.3e-06 0.00027 2 38 .] 237 274 .. 236 274 .. 0.93 3 ! 25.7 0.5 8.7e-07 7.1e-05 2 38 .] 279 316 .. 278 316 .. 0.95 4 ! 23.6 0.1 3.9e-06 0.00032 4 38 .] 323 358 .. 320 358 .. 0.77 5 ? 7.5 0.0 0.5 41 5 37 .. 366 398 .. 362 399 .. 0.86 6 ! 19.9 0.3 5.8e-05 0.0047 3 38 .] 405 440 .. 403 440 .. 0.88 7 ? 7.5 0.0 0.48 39 11 37 .. 463 489 .. 453 490 .. 0.85 Alignments for each domain: == domain 1 score: 37.9 bits; conditional E-value: 1.2e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+++GH ++v+++a+ p ++w+++Gs D+t++iWd sp|O43660|PLRG1_HUMAN 195 KLYRVISGHlGWVRCIAVEPGNQWFVTGSADRTIKIWD 232 6678999******************************9 PP == domain 2 score: 23.9 bits; conditional E-value: 3.3e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +ltGH s v+++ +s +++l+s+++D+ v+ Wd sp|O43660|PLRG1_HUMAN 237 KLKLSLTGHiSTVRGVIVSTRSPYLFSCGEDKQVKCWD 274 566799****99*************************9 PP == domain 3 score: 25.7 bits; conditional E-value: 8.7e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r++ GH s v++l+ +p + l+++s+D t riWd sp|O43660|PLRG1_HUMAN 279 KVIRHYHGHlSAVYGLDLHPTIDVLVTCSRDSTARIWD 316 5689*********************************9 PP == domain 4 score: 23.6 bits; conditional E-value: 3.9e-06 EEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 ++tl+GH + v+++ + +++Gs D t+r+Wd sp|O43660|PLRG1_HUMAN 323 VHTLSGHtNAvatVRCQ---AAEPQIITGSHDTTIRLWD 358 8******8885555666...44444789*99*******9 PP == domain 5 score: 7.5 bits; conditional E-value: 0.5 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 tlt H +sv+++ +p + +asGs +++ W sp|O43660|PLRG1_HUMAN 366 VTLTNHkKSVRAVVLHPRHYTFASGS-PDNIKQW 398 5899**999*****************.8888888 PP == domain 6 score: 19.9 bits; conditional E-value: 5.8e-05 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ l+GH+ ++ l +++dg ++ sG d+gt ++Wd sp|O43660|PLRG1_HUMAN 405 FIQNLSGHNAiINTLTVNSDGVLV-SGADNGTMHLWD 440 57889***7757***********7.8*9********9 PP == domain 7 score: 7.5 bits; conditional E-value: 0.48 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 s++ ++af+++ + l+++ D+t++++ sp|O43660|PLRG1_HUMAN 463 SGIFACAFDQSESRLLTAEADKTIKVY 489 45999*************77*****98 PP >> sp|Q86TI4-1|WDR86_HUMAN Isoform 1 of WD repeat-containing protein 86 OS=Homo sapiens GN=WDR86 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.6 0.1 1.9e-06 0.00015 3 38 .] 7 43 .. 5 43 .. 0.91 2 ? 11.1 0.0 0.036 2.9 7 38 .] 168 198 .. 162 198 .. 0.82 3 ! 22.6 0.0 8.4e-06 0.00068 1 38 [] 202 238 .. 202 238 .. 0.75 4 ! 16.5 0.0 0.00069 0.056 2 37 .. 243 293 .. 242 294 .. 0.79 5 ! 17.9 0.5 0.00025 0.021 2 38 .] 299 336 .. 298 336 .. 0.91 6 ! 16.3 0.0 0.00084 0.068 1 37 [. 340 375 .. 340 375 .. 0.78 7 ? 9.0 0.0 0.17 13 1 31 [. 380 409 .. 380 416 .. 0.71 8 ! 22.6 0.1 8.3e-06 0.00067 2 38 .] 421 456 .. 420 456 .. 0.87 Alignments for each domain: == domain 1 score: 24.6 bits; conditional E-value: 1.9e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 lr++ H ++++ l+ spdg+ l++Gs+Dgt r+W+ sp|Q86TI4-1|WDR86_HUMAN 7 ALRVCADHrGGINWLSLSPDGQRLLTGSEDGTARLWS 43 5788889*999*************************5 PP == domain 2 score: 11.1 bits; conditional E-value: 0.036 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH s vt ++ ++ a+ ++s D+t+r Wd sp|Q86TI4-1|WDR86_HUMAN 168 LGGHeSYVTFCQLEDEAAF--TCSADCTIRRWD 198 67**888*88867777777..7999*******9 PP == domain 3 score: 22.6 bits; conditional E-value: 8.4e-06 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 gqcl++++GH+s v+ + + ++ +s+s+D+t r+W+ sp|Q86TI4-1|WDR86_HUMAN 202 GQCLQVYRGHTSiVNRILVANNQL--FSSSYDRTARVWS 238 79********55479994433333..46888*******5 PP == domain 4 score: 16.5 bits; conditional E-value: 0.00069 EEEEEEESS.SSEEEEEEETTSSE................EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw................lasGsdDgtvriW 37 q r+++GH ++v la + +w l++Gs Dgt ++W sp|Q86TI4-1|WDR86_HUMAN 243 QMSREFRGHrNCVLTLA--YSAPWdlpstpcaeeaaagglLVTGSTDGTAKVW 293 67899****99999994..23444667777788888888789*********** PP == domain 5 score: 17.9 bits; conditional E-value: 0.00025 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +tl+GH + v +l + g+ ++Gs D t+r Wd sp|Q86TI4-1|WDR86_HUMAN 299 CCHQTLRGHtGAVLCLVLDTPGHTAFTGSTDATIRAWD 336 68899****777*****999999999***********9 PP == domain 6 score: 16.3 bits; conditional E-value: 0.00084 TEEEEEEESS.SS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ss......vtslafspdgawlasGsdDgtvriW 37 g++lr+++ H +s v+ l + sGs D+tv+ W sp|Q86TI4-1|WDR86_HUMAN 340 GEQLRVFREHrGSviclelVNRL--------VYSGSADRTVKCW 375 5789******9885444444444........88*********** PP == domain 7 score: 9.0 bits; conditional E-value: 0.17 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETT CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdD 31 g+c+rt+t+H +v++l ++ l++Gs D sp|Q86TI4-1|WDR86_HUMAN 380 GECVRTFTAHrRNVSAL------KYhagtLFTGSGD 409 69********877****......5533333477656 PP == domain 8 score: 22.6 bits; conditional E-value: 8.3e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ r+++GH++ ++++ + +g+ l ++s Dg +r+Wd sp|Q86TI4-1|WDR86_HUMAN 421 ELRRVFRGHTFiINCI--QVHGQVLYTASHDGALRLWD 456 67799****6648***..889999999999*******9 PP >> sp|P35606|COPB2_HUMAN Coatomer subunit beta' OS=Homo sapiens GN=COPB2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.034 2.8 9 38 .] 13 43 .. 6 43 .. 0.82 2 ? 9.0 0.0 0.16 13 13 38 .] 60 85 .. 47 85 .. 0.81 3 ! 28.3 0.0 1.3e-07 1.1e-05 4 38 .] 92 127 .. 89 127 .. 0.92 4 ! 18.2 0.1 0.00021 0.017 1 37 [. 132 170 .. 132 171 .. 0.86 5 ! 27.6 0.0 2.1e-07 1.7e-05 3 38 .] 177 215 .. 175 215 .. 0.91 6 ! 35.4 0.1 7.3e-10 5.9e-08 2 37 .. 220 256 .. 219 257 .. 0.95 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.034 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 + s+ v s++ +p +w++++ ++g+v +W+ sp|P35606|COPB2_HUMAN 13 ARSDrVKSVDLHPTEPWMLASLYNGSVCVWN 43 4444599***********99967*******8 PP == domain 2 score: 9.0 bits; conditional E-value: 0.16 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v++ +f ++w+++G dD +r+++ sp|P35606|COPB2_HUMAN 60 VRAAKFVARKNWVVTGADDMQIRVFN 85 6777788899**************97 PP == domain 3 score: 28.3 bits; conditional E-value: 1.3e-07 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ +++Hs+ ++++a++p +++++++sdD +++Wd sp|P35606|COPB2_HUMAN 92 VHMFEAHSDyIRCIAVHPTQPFILTSSDDMLIKLWD 127 799****556*************************9 PP == domain 4 score: 18.2 bits; conditional E-value: 0.00021 TEEEEEEESSSS.EEEEE.EETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtsla.fspdgawlasGsdDgtvriW 37 ++c ++++GH++ v + +++d++ +as+s D+t+++W sp|P35606|COPB2_HUMAN 132 WSCSQVFEGHTHyVMQIViNPKDNNQFASASLDRTIKVW 170 6899******66797777688888889************ PP == domain 5 score: 27.6 bits; conditional E-value: 2.1e-07 EEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 + tl+GH ++v++++ d+++l+sG dD+ v+iWd sp|P35606|COPB2_HUMAN 177 PNFTLEGHeKGVNCIDyySGGDKPYLISGADDRLVKIWD 215 56799***********888888888*************9 PP == domain 6 score: 35.4 bits; conditional E-value: 7.3e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +c++tl+GH ++v++ +f+p+ + +++Gs+DgtvriW sp|P35606|COPB2_HUMAN 220 TCVQTLEGHaQNVSCASFHPELPIIITGSEDGTVRIW 256 69*******988************************* PP >> sp|P53621|COPA_HUMAN Coatomer subunit alpha OS=Homo sapiens GN=COPA PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.024 2 13 38 .] 12 37 .. 2 37 .. 0.85 2 ! 23.7 0.1 3.7e-06 0.0003 5 38 .] 45 79 .. 41 79 .. 0.91 3 ! 27.2 0.1 2.9e-07 2.3e-05 2 38 .] 84 121 .. 83 121 .. 0.91 4 ! 31.0 0.2 1.9e-08 1.6e-06 2 38 .] 126 163 .. 125 163 .. 0.95 5 ! 22.9 0.1 6.5e-06 0.00053 5 37 .. 199 232 .. 196 233 .. 0.91 6 ! 23.8 0.1 3.5e-06 0.00029 4 38 .] 242 277 .. 239 277 .. 0.93 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.024 EEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 13 vtslafspdgawlasG.sdDgtvriWd 38 v +l+f+p +w++++ + +g + +Wd sp|P53621|COPA_HUMAN 12 VKGLSFHPKRPWILTSlH-NGVIQLWD 37 999*************66.*******9 PP == domain 2 score: 23.7 bits; conditional E-value: 3.7e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ H ++v++++f++ +++++sG+dD ++++W+ sp|P53621|COPA_HUMAN 45 DKFDEHdGPVRGIDFHKQQPLFVSGGDDYKIKVWN 79 56889*888*************************8 PP == domain 3 score: 27.2 bits; conditional E-value: 2.9e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl tl GH + ++ f+++ +w++s+sdD+t+r+W+ sp|P53621|COPA_HUMAN 84 RCLFTLLGHlDYIRTTFFHHEYPWILSASDDQTIRVWN 121 79*******999*5555********************8 PP == domain 4 score: 31.0 bits; conditional E-value: 1.9e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +c+ +ltGH++ v + +f+p ++++s+s D+tvr+Wd sp|P53621|COPA_HUMAN 126 TCVCVLTGHNHyVMCAQFHPTEDLVVSASLDQTVRVWD 163 7999*****888*************************9 PP == domain 5 score: 22.9 bits; conditional E-value: 6.5e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l+GH +v+ af+p ++++sG dD+ v+iW sp|P53621|COPA_HUMAN 199 HVLEGHdRGVNWAAFHPTMPLIVSGADDRQVKIW 232 899***666************************* PP == domain 6 score: 23.8 bits; conditional E-value: 3.5e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + t++GH ++v++ f+p + +++s s+D+++r+Wd sp|P53621|COPA_HUMAN 242 VDTCRGHyNNVSCAVFHPRQELILSNSEDKSIRVWD 277 6799*******9999*********88*********9 PP >> sp|P53621-2|COPA_HUMAN Isoform 2 of Coatomer subunit alpha OS=Homo sapiens GN=COPA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.025 2 13 38 .] 12 37 .. 2 37 .. 0.85 2 ! 23.7 0.1 3.7e-06 0.0003 5 38 .] 45 79 .. 41 79 .. 0.91 3 ! 27.2 0.1 2.9e-07 2.3e-05 2 38 .] 84 121 .. 83 121 .. 0.91 4 ! 30.9 0.2 1.9e-08 1.6e-06 2 38 .] 126 163 .. 125 163 .. 0.95 5 ! 22.9 0.1 6.6e-06 0.00054 5 37 .. 199 232 .. 196 233 .. 0.91 6 ! 23.8 0.1 3.6e-06 0.00029 4 38 .] 242 277 .. 239 277 .. 0.93 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.025 EEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 13 vtslafspdgawlasG.sdDgtvriWd 38 v +l+f+p +w++++ + +g + +Wd sp|P53621-2|COPA_HUMAN 12 VKGLSFHPKRPWILTSlH-NGVIQLWD 37 999*************66.*******9 PP == domain 2 score: 23.7 bits; conditional E-value: 3.7e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ H ++v++++f++ +++++sG+dD ++++W+ sp|P53621-2|COPA_HUMAN 45 DKFDEHdGPVRGIDFHKQQPLFVSGGDDYKIKVWN 79 56889*888*************************8 PP == domain 3 score: 27.2 bits; conditional E-value: 2.9e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl tl GH + ++ f+++ +w++s+sdD+t+r+W+ sp|P53621-2|COPA_HUMAN 84 RCLFTLLGHlDYIRTTFFHHEYPWILSASDDQTIRVWN 121 79*******999*5555********************8 PP == domain 4 score: 30.9 bits; conditional E-value: 1.9e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +c+ +ltGH++ v + +f+p ++++s+s D+tvr+Wd sp|P53621-2|COPA_HUMAN 126 TCVCVLTGHNHyVMCAQFHPTEDLVVSASLDQTVRVWD 163 7999*****888*************************9 PP == domain 5 score: 22.9 bits; conditional E-value: 6.6e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l+GH +v+ af+p ++++sG dD+ v+iW sp|P53621-2|COPA_HUMAN 199 HVLEGHdRGVNWAAFHPTMPLIVSGADDRQVKIW 232 899***666************************* PP == domain 6 score: 23.8 bits; conditional E-value: 3.6e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + t++GH ++v++ f+p + +++s s+D+++r+Wd sp|P53621-2|COPA_HUMAN 242 VDTCRGHyNNVSCAVFHPRQELILSNSEDKSIRVWD 277 6799*******9999*********88*********9 PP >> sp|Q99973-2|TEP1_HUMAN Isoform 2 of Telomerase protein component 1 OS=Homo sapiens GN=TEP1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 8 6.5e+02 14 36 .. 1680 1702 .. 1665 1704 .. 0.87 2 ? 5.3 0.1 2.4 2e+02 8 38 .] 1716 1745 .. 1708 1745 .. 0.82 3 ? 11.8 0.1 0.022 1.8 8 38 .] 1756 1787 .. 1749 1787 .. 0.85 4 ? 12.4 0.0 0.014 1.1 10 36 .. 1797 1826 .. 1791 1828 .. 0.81 5 ? 6.5 0.0 1 81 7 38 .] 1880 1912 .. 1874 1912 .. 0.75 6 ? 3.9 0.0 6.7 5.4e+02 7 32 .. 1918 1950 .. 1914 1955 .. 0.71 7 ? 3.5 0.0 9.2 7.4e+02 15 37 .. 2021 2037 .. 2007 2037 .. 0.83 8 ! 26.8 0.2 4e-07 3.2e-05 3 38 .] 2053 2089 .. 2051 2089 .. 0.95 9 ! 15.2 3.4 0.0018 0.14 4 38 .] 2099 2134 .. 2097 2134 .. 0.86 10 ? 12.8 0.0 0.01 0.83 2 38 .] 2139 2174 .. 2138 2174 .. 0.72 11 ! 19.1 0.0 0.00011 0.0088 4 37 .. 2231 2265 .. 2228 2266 .. 0.91 12 ? 5.8 0.0 1.7 1.4e+02 12 37 .. 2282 2307 .. 2274 2308 .. 0.79 13 ? 8.3 0.0 0.27 22 10 37 .. 2547 2573 .. 2539 2574 .. 0.77 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 8 EEEEEETTSSEEEEEETTSEEEE CS WD40 14 tslafspdgawlasGsdDgtvri 36 t++afs +g+ a G+ +gtv++ sp|Q99973-2|TEP1_HUMAN 1680 TAVAFSTNGQRAAVGTANGTVYL 1702 89**********9**99***986 PP == domain 2 score: 5.3 bits; conditional E-value: 2.4 ESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriWd 38 +G ++++++ f +d ++++++ Dg + +Wd sp|Q99973-2|TEP1_HUMAN 1716 SGCDGISACLFLSDDTLFLTAF-DGLLELWD 1745 55556888889999999999**.*******9 PP == domain 3 score: 11.8 bits; conditional E-value: 0.022 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 ++H+ +t+++ spd ++la+ + g +++Wd sp|Q99973-2|TEP1_HUMAN 1756 KAHQYqITGCCLSPDCRLLATVCLGGCLKLWD 1787 689446**************9999*******9 PP == domain 4 score: 12.4 bits; conditional E-value: 0.014 S...SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 10 H...ssvtslafspdgawlasGsdDgtvri 36 H +s +++af+p+g+ +a+Gs+ g++ + sp|Q99973-2|TEP1_HUMAN 1797 HtypKSLNCVAFHPEGQVIATGSWAGSISF 1826 4334569****************9888865 PP == domain 5 score: 6.5 bits; conditional E-value: 1 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +H ++v + f + g l+++++Dg+v +W+ sp|Q99973-2|TEP1_HUMAN 1880 FPAHhGFVAAALFLHAGCQLLTAGEDGKVQVWS 1912 6778677865557777777889999*******5 PP == domain 6 score: 3.9 bits; conditional E-value: 6.7 EESS.SS.....EEEEEEETTSSEEEEEET.TS CS WD40 7 ltGH.ss.....vtslafspdgawlasGsd.Dg 32 +GH +s s+a spdg+ +a G + Dg sp|Q99973-2|TEP1_HUMAN 1918 PRGHlGSlslspALSVALSPDGDRVAVGYRaDG 1950 57888775544434888*********9964255 PP == domain 7 score: 3.5 bits; conditional E-value: 9.2 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 s + +las+s+D tv +W sp|Q99973-2|TEP1_HUMAN 2021 S------QELLASASEDFTVQLW 2037 3......4889************ PP == domain 8 score: 26.8 bits; conditional E-value: 4e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++l+GH ++v++++fs dg la+G++D+++ Wd sp|Q99973-2|TEP1_HUMAN 2053 CGTELRGHeGPVSCCSFSTDGGSLATGGRDRSLLCWD 2089 7789****999*************************9 PP == domain 9 score: 15.2 bits; conditional E-value: 0.0018 EEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ H ++vt++a+ +d+ +++++s Dg+v +Wd sp|Q99973-2|TEP1_HUMAN 2099 IHSFPaCHrDWVTGCAWTKDNLLISCSS-DGSVGLWD 2134 67776589889************97666.*******9 PP == domain 10 score: 12.8 bits; conditional E-value: 0.01 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q l+ + GH s v+++ ++s s+Dgt+++Wd sp|Q99973-2|TEP1_HUMAN 2139 QRLGQFLGHqSAVSAV--AAVEEHVVSVSRDGTLKVWD 2174 6678899**7777777..222333778899*******9 PP == domain 11 score: 19.1 bits; conditional E-value: 0.00011 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++tl GH ++v++ a+s + +++++s+Dg+vr+W sp|Q99973-2|TEP1_HUMAN 2231 THTLLGHsGPVRAAAVSETSGLMLTASEDGSVRLW 2265 68999**777************************* PP == domain 12 score: 5.8 bits; conditional E-value: 1.7 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 vt++a+ pdg++ +sG g + +W sp|Q99973-2|TEP1_HUMAN 2282 AVTAVAWAPDGSMAVSGNQAGELILW 2307 39***********9999766666666 PP == domain 13 score: 8.3 bits; conditional E-value: 0.27 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H +svt+l + +l+++s+D+ v++W sp|Q99973-2|TEP1_HUMAN 2547 HsGSVTAL--HVLPELLVTASKDRDVKLW 2573 75569999..44444589*********** PP >> sp|Q9UKB1-2|FBW1B_HUMAN Isoform A of F-box/WD repeat-containing protein 11 OS=Homo sapiens GN=FBXW11 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0045 0.37 11 38 .] 207 232 .. 194 232 .. 0.74 2 ! 30.1 0.2 3.6e-08 3e-06 2 38 .] 237 272 .. 236 272 .. 0.89 3 ? 12.6 0.1 0.012 0.99 2 38 .] 277 312 .. 276 312 .. 0.74 4 ! 19.4 0.1 8.6e-05 0.007 4 38 .] 322 355 .. 319 355 .. 0.83 5 ! 24.1 0.1 2.7e-06 0.00022 3 38 .] 361 395 .. 359 395 .. 0.84 6 ! 27.0 0.0 3.3e-07 2.7e-05 1 38 [] 399 435 .. 399 435 .. 0.87 7 ! 15.3 0.1 0.0017 0.13 3 38 .] 450 484 .. 449 484 .. 0.77 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0045 SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 11 ssvtslafspdgaw....lasGsdDgtvriWd 38 ++v++l ++ ++sG +D++++iWd sp|Q9UKB1-2|FBW1B_HUMAN 207 KGVYCL------QYddekIISGLRDNSIKIWD 232 569***......334443779*99*******9 PP == domain 2 score: 30.1 bits; conditional E-value: 3.6e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl++ltGH +sv +l + d + +++Gs D tvr+Wd sp|Q9UKB1-2|FBW1B_HUMAN 237 ECLKVLTGHtGSVLCL--QYDERVIVTGSSDSTVRVWD 272 7********888****..66666699**99*******9 PP == domain 3 score: 12.6 bits; conditional E-value: 0.012 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + l tl H+ v +l+f ++ +++++s+D+++ +Wd sp|Q9UKB1-2|FBW1B_HUMAN 277 EVLNTLIHHNEaVLHLRF--SNGLMVTCSKDRSIAVWD 312 567888889445999944..3444679**********9 PP == domain 4 score: 19.4 bits; conditional E-value: 8.6e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH v+ + + d ++++s+s D+t+++W+ sp|Q9UKB1-2|FBW1B_HUMAN 322 RRVLVGHrAAVNVV--DFDDKYIVSASGDRTIKVWS 355 57899**8888777..669999998877*******5 PP == domain 5 score: 24.1 bits; conditional E-value: 2.7e-06 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +rtl GH ++ +l ++ ++sGs D+t+r+Wd sp|Q9UKB1-2|FBW1B_HUMAN 361 FVRTLNGHkRGIACL------QYrdrlVVSGSSDNTIRLWD 395 689*****555****......66666589**99*******9 PP == domain 6 score: 27.0 bits; conditional E-value: 3.3e-07 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g clr+l+GH v+++ d++ ++sG +Dg++++Wd sp|Q9UKB1-2|FBW1B_HUMAN 399 GACLRVLEGHEElVRCI--RFDNKRIVSGAYDGKIKVWD 435 57********446****..55777799**99*******9 PP == domain 7 score: 15.3 bits; conditional E-value: 0.0017 EEEEEESSSS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgaw....lasGsdDgtvriWd 38 clrtl Hs+ v l+ + ++s+s D t+ iWd sp|Q9UKB1-2|FBW1B_HUMAN 450 CLRTLVEHSGrVFRLQ------FdefqIISSSHDDTILIWD 484 99******445****5......44445446666*******9 PP >> tr|G3V2A4|G3V2A4_HUMAN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphata # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 5.7 4.6e+02 14 36 .. 1023 1045 .. 1008 1047 .. 0.87 2 ? 5.8 0.1 1.7 1.4e+02 8 38 .] 1059 1088 .. 1051 1088 .. 0.82 3 ? 12.3 0.1 0.015 1.2 8 38 .] 1099 1130 .. 1092 1130 .. 0.85 4 ! 12.9 0.0 0.0097 0.79 10 36 .. 1140 1169 .. 1134 1171 .. 0.81 5 ? 7.0 0.0 0.71 57 7 38 .] 1223 1255 .. 1217 1255 .. 0.76 6 ? 4.4 0.0 4.7 3.8e+02 7 32 .. 1261 1293 .. 1257 1298 .. 0.71 7 ? 4.0 0.0 6.4 5.2e+02 15 37 .. 1364 1380 .. 1349 1380 .. 0.83 8 ! 27.3 0.2 2.8e-07 2.3e-05 3 38 .] 1396 1432 .. 1394 1432 .. 0.95 9 ! 15.7 3.4 0.0013 0.1 4 38 .] 1442 1477 .. 1440 1477 .. 0.86 10 ! 13.3 0.0 0.0072 0.59 2 38 .] 1482 1517 .. 1481 1517 .. 0.72 11 ? 3.8 0.0 7.2 5.8e+02 4 37 .. 1523 1566 .. 1520 1567 .. 0.80 12 ! 19.6 0.0 7.6e-05 0.0062 4 37 .. 1574 1608 .. 1571 1609 .. 0.91 13 ? 6.2 0.0 1.2 99 12 37 .. 1625 1650 .. 1617 1651 .. 0.79 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 5.7 EEEEEETTSSEEEEEETTSEEEE CS WD40 14 tslafspdgawlasGsdDgtvri 36 t++afs +g+ a G+ +gtv++ tr|G3V2A4|G3V2A4_HUMAN 1023 TAVAFSTNGQRAAVGTANGTVYL 1045 89**********9**99***986 PP == domain 2 score: 5.8 bits; conditional E-value: 1.7 ESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriWd 38 +G ++++++ f +d ++++++ Dg + +Wd tr|G3V2A4|G3V2A4_HUMAN 1059 SGCDGISACLFLSDDTLFLTAF-DGLLELWD 1088 55556888889999999999**.*******9 PP == domain 3 score: 12.3 bits; conditional E-value: 0.015 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 ++H+ +t+++ spd ++la+ + g +++Wd tr|G3V2A4|G3V2A4_HUMAN 1099 KAHQYqITGCCLSPDCRLLATVCLGGCLKLWD 1130 689446**************9999*******9 PP == domain 4 score: 12.9 bits; conditional E-value: 0.0097 S...SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 10 H...ssvtslafspdgawlasGsdDgtvri 36 H +s +++af+p+g+ +a+Gs+ g++ + tr|G3V2A4|G3V2A4_HUMAN 1140 HtypKSLNCVAFHPEGQVIATGSWAGSISF 1169 4334569****************9888865 PP == domain 5 score: 7.0 bits; conditional E-value: 0.71 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +H ++v + f + g l+++++Dg+v +W+ tr|G3V2A4|G3V2A4_HUMAN 1223 FPAHhGFVAAALFLHAGCQLLTAGEDGKVQVWS 1255 6778677865557777777889999*******5 PP == domain 6 score: 4.4 bits; conditional E-value: 4.7 EESS.SS.....EEEEEEETTSSEEEEEET.TS CS WD40 7 ltGH.ss.....vtslafspdgawlasGsd.Dg 32 +GH +s s+a spdg+ +a G + Dg tr|G3V2A4|G3V2A4_HUMAN 1261 PRGHlGSlslspALSVALSPDGDRVAVGYRaDG 1293 57888775544434888*********9964255 PP == domain 7 score: 4.0 bits; conditional E-value: 6.4 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 s + +las+s+D tv +W tr|G3V2A4|G3V2A4_HUMAN 1364 S------QELLASASEDFTVQLW 1380 3......4889************ PP == domain 8 score: 27.3 bits; conditional E-value: 2.8e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++l+GH ++v++++fs dg la+G++D+++ Wd tr|G3V2A4|G3V2A4_HUMAN 1396 CGTELRGHeGPVSCCSFSTDGGSLATGGRDRSLLCWD 1432 7789****999*************************9 PP == domain 9 score: 15.7 bits; conditional E-value: 0.0013 EEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ H ++vt++a+ +d+ +++++s Dg+v +Wd tr|G3V2A4|G3V2A4_HUMAN 1442 IHSFPaCHrDWVTGCAWTKDNLLISCSS-DGSVGLWD 1477 67776589889************97666.*******9 PP == domain 10 score: 13.3 bits; conditional E-value: 0.0072 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q l+ + GH s v+++ ++s s+Dgt+++Wd tr|G3V2A4|G3V2A4_HUMAN 1482 QRLGQFLGHqSAVSAV--AAVEEHVVSVSRDGTLKVWD 1517 6678899**7777777..222333778899*******9 PP == domain 11 score: 3.8 bits; conditional E-value: 7.2 EEEEESS.SSEEEEE........EETTSSEEE.EEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla........fspdgawla.sGsdDgtvriW 37 l+++ +H ++++++a +p + +l+ + + Dg r+W tr|G3V2A4|G3V2A4_HUMAN 1523 LTSIPAHsGPISHCAaamepraaGQPGSELLVvTVGLDGATRLW 1566 677889*777*666669******99999998635577******* PP == domain 12 score: 19.6 bits; conditional E-value: 7.6e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++tl GH ++v++ a+s + +++++s+Dg+vr+W tr|G3V2A4|G3V2A4_HUMAN 1574 THTLLGHsGPVRAAAVSETSGLMLTASEDGSVRLW 1608 68999**777************************* PP == domain 13 score: 6.2 bits; conditional E-value: 1.2 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 vt++a+ pdg++ +sG g + +W tr|G3V2A4|G3V2A4_HUMAN 1625 AVTAVAWAPDGSMAVSGNQAGELILW 1650 39***********9999766666666 PP >> tr|B4DH70|B4DH70_HUMAN F-box/WD repeat-containing protein 11 OS=Homo sapiens GN=FBXW11 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0046 0.37 11 38 .] 209 234 .. 196 234 .. 0.74 2 ! 30.1 0.2 3.7e-08 3e-06 2 38 .] 239 274 .. 238 274 .. 0.89 3 ? 12.6 0.1 0.012 1 2 38 .] 279 314 .. 278 314 .. 0.74 4 ! 19.4 0.1 8.7e-05 0.007 4 38 .] 324 357 .. 321 357 .. 0.83 5 ! 24.1 0.1 2.7e-06 0.00022 3 38 .] 363 397 .. 361 397 .. 0.84 6 ! 27.0 0.0 3.3e-07 2.7e-05 1 38 [] 401 437 .. 401 437 .. 0.87 7 ! 15.3 0.1 0.0017 0.14 3 38 .] 452 486 .. 451 486 .. 0.77 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0046 SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 11 ssvtslafspdgaw....lasGsdDgtvriWd 38 ++v++l ++ ++sG +D++++iWd tr|B4DH70|B4DH70_HUMAN 209 KGVYCL------QYddekIISGLRDNSIKIWD 234 569***......334443779*99*******9 PP == domain 2 score: 30.1 bits; conditional E-value: 3.7e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl++ltGH +sv +l + d + +++Gs D tvr+Wd tr|B4DH70|B4DH70_HUMAN 239 ECLKVLTGHtGSVLCL--QYDERVIVTGSSDSTVRVWD 274 7********888****..66666699**99*******9 PP == domain 3 score: 12.6 bits; conditional E-value: 0.012 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + l tl H+ v +l+f ++ +++++s+D+++ +Wd tr|B4DH70|B4DH70_HUMAN 279 EVLNTLIHHNEaVLHLRF--SNGLMVTCSKDRSIAVWD 314 567888889445999944..3444679**********9 PP == domain 4 score: 19.4 bits; conditional E-value: 8.7e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH v+ + + d ++++s+s D+t+++W+ tr|B4DH70|B4DH70_HUMAN 324 RRVLVGHrAAVNVV--DFDDKYIVSASGDRTIKVWS 357 57899**8888777..669999998877*******5 PP == domain 5 score: 24.1 bits; conditional E-value: 2.7e-06 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +rtl GH ++ +l ++ ++sGs D+t+r+Wd tr|B4DH70|B4DH70_HUMAN 363 FVRTLNGHkRGIACL------QYrdrlVVSGSSDNTIRLWD 397 689*****555****......66666589**99*******9 PP == domain 6 score: 27.0 bits; conditional E-value: 3.3e-07 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g clr+l+GH v+++ d++ ++sG +Dg++++Wd tr|B4DH70|B4DH70_HUMAN 401 GACLRVLEGHEElVRCI--RFDNKRIVSGAYDGKIKVWD 437 57********446****..55777799**99*******9 PP == domain 7 score: 15.3 bits; conditional E-value: 0.0017 EEEEEESSSS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgaw....lasGsdDgtvriWd 38 clrtl Hs+ v l+ + ++s+s D t+ iWd tr|B4DH70|B4DH70_HUMAN 452 CLRTLVEHSGrVFRLQ------FdefqIISSSHDDTILIWD 486 99******445****5......44445446666*******9 PP >> sp|Q99973|TEP1_HUMAN Telomerase protein component 1 OS=Homo sapiens GN=TEP1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 8.1 6.5e+02 14 36 .. 1680 1702 .. 1665 1704 .. 0.87 2 ? 5.3 0.1 2.4 2e+02 8 38 .] 1716 1745 .. 1708 1745 .. 0.82 3 ? 11.8 0.1 0.022 1.8 8 38 .] 1756 1787 .. 1749 1787 .. 0.85 4 ? 12.4 0.0 0.014 1.1 10 36 .. 1797 1826 .. 1791 1828 .. 0.81 5 ? 6.5 0.0 1 81 7 38 .] 1880 1912 .. 1874 1912 .. 0.75 6 ? 3.9 0.0 6.7 5.4e+02 7 32 .. 1918 1950 .. 1914 1955 .. 0.71 7 ? 3.5 0.0 9.2 7.4e+02 15 37 .. 2021 2037 .. 2007 2037 .. 0.83 8 ! 26.8 0.2 4e-07 3.3e-05 3 38 .] 2053 2089 .. 2051 2089 .. 0.95 9 ! 15.2 3.4 0.0018 0.14 4 38 .] 2099 2134 .. 2097 2134 .. 0.86 10 ? 12.8 0.0 0.01 0.84 2 38 .] 2139 2174 .. 2138 2174 .. 0.72 11 ! 19.1 0.0 0.00011 0.0088 4 37 .. 2231 2265 .. 2228 2266 .. 0.91 12 ? 5.8 0.0 1.7 1.4e+02 12 37 .. 2282 2307 .. 2274 2308 .. 0.79 13 ? 8.3 0.0 0.28 22 10 37 .. 2554 2580 .. 2546 2581 .. 0.77 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 8.1 EEEEEETTSSEEEEEETTSEEEE CS WD40 14 tslafspdgawlasGsdDgtvri 36 t++afs +g+ a G+ +gtv++ sp|Q99973|TEP1_HUMAN 1680 TAVAFSTNGQRAAVGTANGTVYL 1702 89**********9**99***986 PP == domain 2 score: 5.3 bits; conditional E-value: 2.4 ESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriWd 38 +G ++++++ f +d ++++++ Dg + +Wd sp|Q99973|TEP1_HUMAN 1716 SGCDGISACLFLSDDTLFLTAF-DGLLELWD 1745 55556888889999999999**.*******9 PP == domain 3 score: 11.8 bits; conditional E-value: 0.022 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 ++H+ +t+++ spd ++la+ + g +++Wd sp|Q99973|TEP1_HUMAN 1756 KAHQYqITGCCLSPDCRLLATVCLGGCLKLWD 1787 689446**************9999*******9 PP == domain 4 score: 12.4 bits; conditional E-value: 0.014 S...SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 10 H...ssvtslafspdgawlasGsdDgtvri 36 H +s +++af+p+g+ +a+Gs+ g++ + sp|Q99973|TEP1_HUMAN 1797 HtypKSLNCVAFHPEGQVIATGSWAGSISF 1826 4334569****************9888865 PP == domain 5 score: 6.5 bits; conditional E-value: 1 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +H ++v + f + g l+++++Dg+v +W+ sp|Q99973|TEP1_HUMAN 1880 FPAHhGFVAAALFLHAGCQLLTAGEDGKVQVWS 1912 6778677865557777777889999*******5 PP == domain 6 score: 3.9 bits; conditional E-value: 6.7 EESS.SS.....EEEEEEETTSSEEEEEET.TS CS WD40 7 ltGH.ss.....vtslafspdgawlasGsd.Dg 32 +GH +s s+a spdg+ +a G + Dg sp|Q99973|TEP1_HUMAN 1918 PRGHlGSlslspALSVALSPDGDRVAVGYRaDG 1950 57888775544434888*********9964255 PP == domain 7 score: 3.5 bits; conditional E-value: 9.2 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 s + +las+s+D tv +W sp|Q99973|TEP1_HUMAN 2021 S------QELLASASEDFTVQLW 2037 3......4889************ PP == domain 8 score: 26.8 bits; conditional E-value: 4e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++l+GH ++v++++fs dg la+G++D+++ Wd sp|Q99973|TEP1_HUMAN 2053 CGTELRGHeGPVSCCSFSTDGGSLATGGRDRSLLCWD 2089 7789****999*************************9 PP == domain 9 score: 15.2 bits; conditional E-value: 0.0018 EEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ H ++vt++a+ +d+ +++++s Dg+v +Wd sp|Q99973|TEP1_HUMAN 2099 IHSFPaCHrDWVTGCAWTKDNLLISCSS-DGSVGLWD 2134 67776589889************97666.*******9 PP == domain 10 score: 12.8 bits; conditional E-value: 0.01 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q l+ + GH s v+++ ++s s+Dgt+++Wd sp|Q99973|TEP1_HUMAN 2139 QRLGQFLGHqSAVSAV--AAVEEHVVSVSRDGTLKVWD 2174 6678899**7777777..222333778899*******9 PP == domain 11 score: 19.1 bits; conditional E-value: 0.00011 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++tl GH ++v++ a+s + +++++s+Dg+vr+W sp|Q99973|TEP1_HUMAN 2231 THTLLGHsGPVRAAAVSETSGLMLTASEDGSVRLW 2265 68999**777************************* PP == domain 12 score: 5.8 bits; conditional E-value: 1.7 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 vt++a+ pdg++ +sG g + +W sp|Q99973|TEP1_HUMAN 2282 AVTAVAWAPDGSMAVSGNQAGELILW 2307 39***********9999766666666 PP == domain 13 score: 8.3 bits; conditional E-value: 0.28 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H +svt+l + +l+++s+D+ v++W sp|Q99973|TEP1_HUMAN 2554 HsGSVTAL--HVLPELLVTASKDRDVKLW 2580 75569999..44444589*********** PP >> sp|Q9UKB1|FBW1B_HUMAN F-box/WD repeat-containing protein 11 OS=Homo sapiens GN=FBXW11 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.0 0.0049 0.4 11 38 .] 241 266 .. 228 266 .. 0.74 2 ! 30.0 0.2 4e-08 3.2e-06 2 38 .] 271 306 .. 270 306 .. 0.89 3 ? 12.5 0.1 0.013 1.1 2 38 .] 311 346 .. 310 346 .. 0.74 4 ! 19.3 0.1 9.4e-05 0.0076 4 38 .] 356 389 .. 353 389 .. 0.83 5 ! 24.0 0.1 3e-06 0.00024 3 38 .] 395 429 .. 393 429 .. 0.84 6 ! 26.9 0.0 3.6e-07 2.9e-05 1 38 [] 433 469 .. 433 469 .. 0.87 7 ! 15.2 0.1 0.0018 0.15 3 38 .] 484 518 .. 483 518 .. 0.77 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.0049 SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 11 ssvtslafspdgaw....lasGsdDgtvriWd 38 ++v++l ++ ++sG +D++++iWd sp|Q9UKB1|FBW1B_HUMAN 241 KGVYCL------QYddekIISGLRDNSIKIWD 266 569***......334443779*99*******9 PP == domain 2 score: 30.0 bits; conditional E-value: 4e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl++ltGH +sv +l + d + +++Gs D tvr+Wd sp|Q9UKB1|FBW1B_HUMAN 271 ECLKVLTGHtGSVLCL--QYDERVIVTGSSDSTVRVWD 306 7********888****..66666699**99*******9 PP == domain 3 score: 12.5 bits; conditional E-value: 0.013 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + l tl H+ v +l+f ++ +++++s+D+++ +Wd sp|Q9UKB1|FBW1B_HUMAN 311 EVLNTLIHHNEaVLHLRF--SNGLMVTCSKDRSIAVWD 346 567888889445999944..3444679**********9 PP == domain 4 score: 19.3 bits; conditional E-value: 9.4e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH v+ + + d ++++s+s D+t+++W+ sp|Q9UKB1|FBW1B_HUMAN 356 RRVLVGHrAAVNVV--DFDDKYIVSASGDRTIKVWS 389 57899**8888777..669999998877*******5 PP == domain 5 score: 24.0 bits; conditional E-value: 3e-06 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +rtl GH ++ +l ++ ++sGs D+t+r+Wd sp|Q9UKB1|FBW1B_HUMAN 395 FVRTLNGHkRGIACL------QYrdrlVVSGSSDNTIRLWD 429 689*****555****......66666589**99*******9 PP == domain 6 score: 26.9 bits; conditional E-value: 3.6e-07 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g clr+l+GH v+++ d++ ++sG +Dg++++Wd sp|Q9UKB1|FBW1B_HUMAN 433 GACLRVLEGHEElVRCI--RFDNKRIVSGAYDGKIKVWD 469 57********446****..55777799**99*******9 PP == domain 7 score: 15.2 bits; conditional E-value: 0.0018 EEEEEESSSS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgaw....lasGsdDgtvriWd 38 clrtl Hs+ v l+ + ++s+s D t+ iWd sp|Q9UKB1|FBW1B_HUMAN 484 CLRTLVEHSGrVFRLQ------FdefqIISSSHDDTILIWD 518 99******445****5......44445446666*******9 PP >> sp|Q9UKB1-3|FBW1B_HUMAN Isoform B of F-box/WD repeat-containing protein 11 OS=Homo sapiens GN=FBXW11 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0048 0.39 11 38 .] 228 253 .. 215 253 .. 0.74 2 ! 30.0 0.2 3.8e-08 3.1e-06 2 38 .] 258 293 .. 257 293 .. 0.89 3 ? 12.5 0.1 0.013 1 2 38 .] 298 333 .. 297 333 .. 0.74 4 ! 19.3 0.1 9.1e-05 0.0074 4 38 .] 343 376 .. 340 376 .. 0.83 5 ! 24.1 0.1 2.9e-06 0.00023 3 38 .] 382 416 .. 380 416 .. 0.84 6 ! 27.0 0.0 3.5e-07 2.8e-05 1 38 [] 420 456 .. 420 456 .. 0.87 7 ! 15.3 0.1 0.0017 0.14 3 38 .] 471 505 .. 470 505 .. 0.77 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0048 SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 11 ssvtslafspdgaw....lasGsdDgtvriWd 38 ++v++l ++ ++sG +D++++iWd sp|Q9UKB1-3|FBW1B_HUMAN 228 KGVYCL------QYddekIISGLRDNSIKIWD 253 569***......334443779*99*******9 PP == domain 2 score: 30.0 bits; conditional E-value: 3.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl++ltGH +sv +l + d + +++Gs D tvr+Wd sp|Q9UKB1-3|FBW1B_HUMAN 258 ECLKVLTGHtGSVLCL--QYDERVIVTGSSDSTVRVWD 293 7********888****..66666699**99*******9 PP == domain 3 score: 12.5 bits; conditional E-value: 0.013 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + l tl H+ v +l+f ++ +++++s+D+++ +Wd sp|Q9UKB1-3|FBW1B_HUMAN 298 EVLNTLIHHNEaVLHLRF--SNGLMVTCSKDRSIAVWD 333 567888889445999944..3444679**********9 PP == domain 4 score: 19.3 bits; conditional E-value: 9.1e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH v+ + + d ++++s+s D+t+++W+ sp|Q9UKB1-3|FBW1B_HUMAN 343 RRVLVGHrAAVNVV--DFDDKYIVSASGDRTIKVWS 376 57899**8888777..669999998877*******5 PP == domain 5 score: 24.1 bits; conditional E-value: 2.9e-06 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +rtl GH ++ +l ++ ++sGs D+t+r+Wd sp|Q9UKB1-3|FBW1B_HUMAN 382 FVRTLNGHkRGIACL------QYrdrlVVSGSSDNTIRLWD 416 689*****555****......66666589**99*******9 PP == domain 6 score: 27.0 bits; conditional E-value: 3.5e-07 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g clr+l+GH v+++ d++ ++sG +Dg++++Wd sp|Q9UKB1-3|FBW1B_HUMAN 420 GACLRVLEGHEElVRCI--RFDNKRIVSGAYDGKIKVWD 456 57********446****..55777799**99*******9 PP == domain 7 score: 15.3 bits; conditional E-value: 0.0017 EEEEEESSSS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgaw....lasGsdDgtvriWd 38 clrtl Hs+ v l+ + ++s+s D t+ iWd sp|Q9UKB1-3|FBW1B_HUMAN 471 CLRTLVEHSGrVFRLQ------FdefqIISSSHDDTILIWD 505 99******445****5......44445446666*******9 PP >> tr|D6RAC2|D6RAC2_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 0.00013 0.01 4 38 .] 8 44 .. 5 44 .. 0.87 2 ! 36.0 0.6 4.8e-10 3.9e-08 3 38 .] 55 91 .. 53 91 .. 0.93 3 ! 24.1 0.8 2.7e-06 0.00022 9 38 .] 98 130 .. 92 130 .. 0.89 4 ! 24.3 0.2 2.5e-06 0.0002 7 38 .] 140 172 .. 134 172 .. 0.86 5 ! 23.1 0.1 5.9e-06 0.00048 2 38 .] 177 212 .. 176 212 .. 0.87 6 ! 18.7 0.0 0.00014 0.012 13 37 .. 238 262 .. 225 263 .. 0.90 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 0.00013 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s+s+D+t+ +W+ tr|D6RAC2|D6RAC2_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRDKTIIMWK 44 5799***666****99888888899***********6 PP == domain 2 score: 36.0 bits; conditional E-value: 4.8e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6RAC2|D6RAC2_HUMAN 55 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 91 7899****667************99***********9 PP == domain 3 score: 24.1 bits; conditional E-value: 2.7e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|D6RAC2|D6RAC2_HUMAN 98 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 130 68556*************989***********8 PP == domain 4 score: 24.3 bits; conditional E-value: 2.5e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd tr|D6RAC2|D6RAC2_HUMAN 140 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 172 3499666*************************9 PP == domain 5 score: 23.1 bits; conditional E-value: 5.9e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+tl+G + +++l+fsp+ wl++++ ++++iWd tr|D6RAC2|D6RAC2_HUMAN 177 KHLYTLDGG-DiINALCFSPNRYWLCAAT-GPSIKIWD 212 778888887.448************9888.*******9 PP == domain 6 score: 18.7 bits; conditional E-value: 0.00014 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 tsla+s dg+ l++G D+ vr+W tr|D6RAC2|D6RAC2_HUMAN 238 CTSLAWSADGQTLFAGYTDNLVRVW 262 59**************88******* PP >> tr|I3L3N5|I3L3N5_HUMAN Platelet-activating factor acetylhydrolase IB subunit alpha (Fragment) OS=Homo sapiens GN=PAF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.1 5.6 4.6e+02 30 38 .] 2 10 .. 1 10 [. 0.87 2 ! 34.0 0.1 2.1e-09 1.7e-07 2 37 .. 15 51 .. 14 52 .. 0.93 3 ! 31.4 0.1 1.4e-08 1.2e-06 2 37 .. 57 93 .. 56 94 .. 0.96 4 ? 8.9 0.0 0.18 14 2 25 .. 99 123 .. 98 132 .. 0.77 5 ! 29.5 1.4 5.7e-08 4.6e-06 9 38 .] 134 164 .. 126 164 .. 0.93 6 ! 35.1 0.0 9.6e-10 7.8e-08 2 37 .. 169 205 .. 168 206 .. 0.93 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 5.6 TTSEEEEEE CS WD40 30 dDgtvriWd 38 D t+++Wd tr|I3L3N5|I3L3N5_HUMAN 2 ADMTIKLWD 10 59******9 PP == domain 2 score: 34.0 bits; conditional E-value: 2.1e-09 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +c+rt GH++ v+s+a p+g+ ++s+s+D+t+++W tr|I3L3N5|I3L3N5_HUMAN 15 ECIRTMHGHDHnVSSVAIMPNGDHIVSASRDKTIKMW 51 8********556************************* PP == domain 3 score: 31.4 bits; conditional E-value: 1.4e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++t+tGH +v+ ++ ++dg+++as+s D+tvr+W tr|I3L3N5|I3L3N5_HUMAN 57 YCVKTFTGHrEWVRMVRPNQDGTLIASCSNDQTVRVW 93 69*******999************************* PP == domain 4 score: 8.9 bits; conditional E-value: 0.18 EEEEEEESSSS.EEEEEEETTSSEE CS WD40 2 qclrtltGHss.vtslafspdgawl 25 +c +l+ H + v ++++ p++++ tr|I3L3N5|I3L3N5_HUMAN 99 ECKAELREHEHvVECISWAPESSYS 123 688999***8867*********992 PP == domain 5 score: 29.5 bits; conditional E-value: 5.7e-08 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++v+++ f++ g++++s+ dD+t+r+Wd tr|I3L3N5|I3L3N5_HUMAN 134 GHdNWVRGVLFHSGGKFILSCADDKTLRVWD 164 9*999*************************9 PP == domain 6 score: 35.1 bits; conditional E-value: 9.6e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +c++tl +H +vtsl+f++ +++++Gs D+tv++W tr|I3L3N5|I3L3N5_HUMAN 169 RCMKTLNAHeHFVTSLDFHKTAPYVVTGSVDQTVKVW 205 79*******666************************* PP >> tr|Q68DS0|Q68DS0_HUMAN F-box/WD repeat-containing protein 1A OS=Homo sapiens GN=DKFZp781N011 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.2 0.0011 0.089 11 38 .] 263 288 .. 247 288 .. 0.75 2 ! 28.3 0.2 1.3e-07 1e-05 2 38 .] 293 328 .. 292 328 .. 0.88 3 ? 11.5 0.0 0.026 2.1 3 38 .] 334 368 .. 332 368 .. 0.76 4 ! 20.5 0.1 3.8e-05 0.0031 4 38 .] 378 411 .. 375 411 .. 0.84 5 ! 24.0 0.1 3.1e-06 0.00025 3 38 .] 417 451 .. 415 451 .. 0.84 6 ! 26.8 0.0 3.8e-07 3.1e-05 1 38 [] 455 491 .. 455 491 .. 0.86 7 ! 15.2 0.1 0.0018 0.15 3 38 .] 506 540 .. 505 540 .. 0.79 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0011 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v++l + d + ++sG +D+t++iWd tr|Q68DS0|Q68DS0_HUMAN 263 KGVYCL--QYDDQKIVSGLRDNTIKIWD 288 559***..55666699**99*******9 PP == domain 2 score: 28.3 bits; conditional E-value: 1.3e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c r+ltGH +sv +l + d + +++Gs D tvr+Wd tr|Q68DS0|Q68DS0_HUMAN 293 ECKRILTGHtGSVLCL--QYDERVIITGSSDSTVRVWD 328 799******888****..66666699**99*******9 PP == domain 3 score: 11.5 bits; conditional E-value: 0.026 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l tl H v +l ++ +++++s+D+++ +Wd tr|Q68DS0|Q68DS0_HUMAN 334 MLNTLIHHcEAVLHL--RFNNGMMVTCSKDRSIAVWD 368 567888885559999..335555889**********9 PP == domain 4 score: 20.5 bits; conditional E-value: 3.8e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH v+ + + d ++++s+s D+t+++W+ tr|Q68DS0|Q68DS0_HUMAN 378 RRVLVGHrAAVNVV--DFDDKYIVSASGDRTIKVWN 411 57899**8888777..669999998877*******8 PP == domain 5 score: 24.0 bits; conditional E-value: 3.1e-06 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +rtl GH ++ +l ++ ++sGs D+t+r+Wd tr|Q68DS0|Q68DS0_HUMAN 417 FVRTLNGHkRGIACL------QYrdrlVVSGSSDNTIRLWD 451 689*****555****......66666589**99*******9 PP == domain 6 score: 26.8 bits; conditional E-value: 3.8e-07 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g clr+l+GH v+++ d++ ++sG +Dg++++Wd tr|Q68DS0|Q68DS0_HUMAN 455 GACLRVLEGHEElVRCI--RFDNKRIVSGAYDGKIKVWD 491 57********446****..55777799**99*******9 PP == domain 7 score: 15.2 bits; conditional E-value: 0.0018 EEEEEESSSS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgaw....lasGsdDgtvriWd 38 clrtl Hs+ v l ++ ++s+s D t+ iWd tr|Q68DS0|Q68DS0_HUMAN 506 CLRTLVEHSGrVFRL------QFdefqIVSSSHDDTILIWD 540 99******445****......555555556766*******9 PP >> sp|Q9Y297-2|FBW1A_HUMAN Isoform 2 of F-box/WD repeat-containing protein 1A OS=Homo sapiens GN=BTRC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.2 0.0011 0.09 11 38 .] 268 293 .. 252 293 .. 0.75 2 ! 28.3 0.2 1.3e-07 1.1e-05 2 38 .] 298 333 .. 297 333 .. 0.88 3 ? 11.5 0.0 0.027 2.2 3 38 .] 339 373 .. 337 373 .. 0.76 4 ! 20.5 0.1 3.8e-05 0.0031 4 38 .] 383 416 .. 380 416 .. 0.84 5 ! 23.9 0.1 3.1e-06 0.00025 3 38 .] 422 456 .. 420 456 .. 0.84 6 ! 26.8 0.0 3.8e-07 3.1e-05 1 38 [] 460 496 .. 460 496 .. 0.86 7 ! 15.2 0.1 0.0018 0.15 3 38 .] 511 545 .. 510 545 .. 0.79 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0011 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v++l + d + ++sG +D+t++iWd sp|Q9Y297-2|FBW1A_HUMAN 268 KGVYCL--QYDDQKIVSGLRDNTIKIWD 293 559***..55666699**99*******9 PP == domain 2 score: 28.3 bits; conditional E-value: 1.3e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c r+ltGH +sv +l + d + +++Gs D tvr+Wd sp|Q9Y297-2|FBW1A_HUMAN 298 ECKRILTGHtGSVLCL--QYDERVIITGSSDSTVRVWD 333 799******888****..66666699**99*******9 PP == domain 3 score: 11.5 bits; conditional E-value: 0.027 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l tl H v +l ++ +++++s+D+++ +Wd sp|Q9Y297-2|FBW1A_HUMAN 339 MLNTLIHHcEAVLHL--RFNNGMMVTCSKDRSIAVWD 373 567888885559999..335555889**********9 PP == domain 4 score: 20.5 bits; conditional E-value: 3.8e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH v+ + + d ++++s+s D+t+++W+ sp|Q9Y297-2|FBW1A_HUMAN 383 RRVLVGHrAAVNVV--DFDDKYIVSASGDRTIKVWN 416 57899**8888777..669999998877*******8 PP == domain 5 score: 23.9 bits; conditional E-value: 3.1e-06 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +rtl GH ++ +l ++ ++sGs D+t+r+Wd sp|Q9Y297-2|FBW1A_HUMAN 422 FVRTLNGHkRGIACL------QYrdrlVVSGSSDNTIRLWD 456 689*****555****......66666589**99*******9 PP == domain 6 score: 26.8 bits; conditional E-value: 3.8e-07 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g clr+l+GH v+++ d++ ++sG +Dg++++Wd sp|Q9Y297-2|FBW1A_HUMAN 460 GACLRVLEGHEElVRCI--RFDNKRIVSGAYDGKIKVWD 496 57********446****..55777799**99*******9 PP == domain 7 score: 15.2 bits; conditional E-value: 0.0018 EEEEEESSSS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgaw....lasGsdDgtvriWd 38 clrtl Hs+ v l ++ ++s+s D t+ iWd sp|Q9Y297-2|FBW1A_HUMAN 511 CLRTLVEHSGrVFRL------QFdefqIVSSSHDDTILIWD 545 99******445****......555555556766*******9 PP >> sp|Q9Y297|FBW1A_HUMAN F-box/WD repeat-containing protein 1A OS=Homo sapiens GN=BTRC PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.2 0.0012 0.097 11 38 .] 304 329 .. 288 329 .. 0.75 2 ! 28.2 0.2 1.4e-07 1.1e-05 2 38 .] 334 369 .. 333 369 .. 0.88 3 ? 11.4 0.0 0.029 2.3 3 38 .] 375 409 .. 373 409 .. 0.76 4 ! 20.4 0.1 4.1e-05 0.0034 4 38 .] 419 452 .. 416 452 .. 0.84 5 ! 23.8 0.1 3.4e-06 0.00028 3 38 .] 458 492 .. 456 492 .. 0.84 6 ! 26.7 0.0 4.1e-07 3.4e-05 1 38 [] 496 532 .. 496 532 .. 0.86 7 ! 15.1 0.1 0.002 0.16 3 38 .] 547 581 .. 546 581 .. 0.79 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 0.0012 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v++l + d + ++sG +D+t++iWd sp|Q9Y297|FBW1A_HUMAN 304 KGVYCL--QYDDQKIVSGLRDNTIKIWD 329 559***..55666699**99*******9 PP == domain 2 score: 28.2 bits; conditional E-value: 1.4e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c r+ltGH +sv +l + d + +++Gs D tvr+Wd sp|Q9Y297|FBW1A_HUMAN 334 ECKRILTGHtGSVLCL--QYDERVIITGSSDSTVRVWD 369 799******888****..66666699**99*******9 PP == domain 3 score: 11.4 bits; conditional E-value: 0.029 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l tl H v +l ++ +++++s+D+++ +Wd sp|Q9Y297|FBW1A_HUMAN 375 MLNTLIHHcEAVLHL--RFNNGMMVTCSKDRSIAVWD 409 567888885559999..335555889**********9 PP == domain 4 score: 20.4 bits; conditional E-value: 4.1e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH v+ + + d ++++s+s D+t+++W+ sp|Q9Y297|FBW1A_HUMAN 419 RRVLVGHrAAVNVV--DFDDKYIVSASGDRTIKVWN 452 57899**8888777..669999998877*******8 PP == domain 5 score: 23.8 bits; conditional E-value: 3.4e-06 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +rtl GH ++ +l ++ ++sGs D+t+r+Wd sp|Q9Y297|FBW1A_HUMAN 458 FVRTLNGHkRGIACL------QYrdrlVVSGSSDNTIRLWD 492 689*****555****......66666589**99*******9 PP == domain 6 score: 26.7 bits; conditional E-value: 4.1e-07 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g clr+l+GH v+++ d++ ++sG +Dg++++Wd sp|Q9Y297|FBW1A_HUMAN 496 GACLRVLEGHEElVRCI--RFDNKRIVSGAYDGKIKVWD 532 57********446****..55777799**99*******9 PP == domain 7 score: 15.1 bits; conditional E-value: 0.002 EEEEEESSSS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgaw....lasGsdDgtvriWd 38 clrtl Hs+ v l ++ ++s+s D t+ iWd sp|Q9Y297|FBW1A_HUMAN 547 CLRTLVEHSGrVFRL------QFdefqIVSSSHDDTILIWD 581 99******445****......555555556766*******9 PP >> tr|E9PCP0|E9PCP0_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 OS=Homo sapiens GN=GNB3 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 1.7e-06 0.00014 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 12.9 0.0 0.0098 0.79 12 38 .] 99 125 .. 86 125 .. 0.86 3 ? 11.1 0.2 0.036 2.9 4 33 .. 136 165 .. 133 169 .. 0.84 4 ! 19.8 0.1 6.4e-05 0.0052 2 38 .] 174 211 .. 173 211 .. 0.90 5 ! 33.1 0.1 3.9e-09 3.2e-07 1 38 [] 215 253 .. 215 253 .. 0.96 6 ! 19.2 0.1 0.0001 0.0081 10 38 .] 265 297 .. 258 297 .. 0.83 7 ! 23.3 0.4 4.9e-06 0.00039 4 38 .] 304 339 .] 301 339 .] 0.93 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 1.7e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ +Wd tr|E9PCP0|E9PCP0_HUMAN 48 RRTLRGHlAKIYAMHWATDSKLLVSASQDGKLIVWD 83 689****999*************************9 PP == domain 2 score: 12.9 bits; conditional E-value: 0.0098 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ tr|E9PCP0|E9PCP0_HUMAN 99 WVMTCAYAPSGNFVACGGLDNMCSIYN 125 488889******************997 PP == domain 3 score: 11.1 bits; conditional E-value: 0.036 EEEEESS.SSEEEEEEETTSSEEEEEETTSE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgt 33 r+l++H + ++++f +d++ ++s++ D t tr|E9PCP0|E9PCP0_HUMAN 136 SRELSAHtGYLSCCRFLDDNNIVTSSG-DTT 165 6899***666************98888.877 PP == domain 4 score: 19.8 bits; conditional E-value: 6.4e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+ +++ GH ++ sla+spd ++++sG D + ++Wd tr|E9PCP0|E9PCP0_HUMAN 174 QQKTVFVGHtGDCMSLAVSPDFNLFISGACDASAKLWD 211 6677899**88899**************77*******9 PP == domain 5 score: 33.1 bits; conditional E-value: 3.9e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c +t+tGH s++++++f p+g +++GsdD ++r++d tr|E9PCP0|E9PCP0_HUMAN 215 GTCRQTFTGHeSDINAICFFPNGEAICTGSDDASCRLFD 253 6799******999************************98 PP == domain 6 score: 19.2 bits; conditional E-value: 0.0001 SSS....EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss....vtslafspdgawlasGsdDgtvriWd 38 H s +ts+afs +g++l++G dD ++ +Wd tr|E9PCP0|E9PCP0_HUMAN 265 HESiicgITSVAFSLSGRLLFAGYDDFNCNVWD 297 62335559************************9 PP == domain 7 score: 23.3 bits; conditional E-value: 4.9e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++l+GH + v++l + dg +a+Gs+D ++iW+ tr|E9PCP0|E9PCP0_HUMAN 304 VGILSGHdNRVSCLGVTADGMAVATGSWDSFLKIWN 339 789****888*************************8 PP >> sp|Q9NYS7|WSB2_HUMAN WD repeat and SOCS box-containing protein 2 OS=Homo sapiens GN=WSB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.2 0.38 31 14 26 .. 30 42 .. 14 50 .. 0.83 2 ? 10.9 0.0 0.043 3.4 10 37 .. 115 138 .. 107 139 .. 0.73 3 ! 31.9 0.1 9.5e-09 7.7e-07 4 38 .] 146 182 .. 143 182 .. 0.87 4 ! 22.2 0.3 1.1e-05 0.00089 1 38 [] 187 225 .. 187 225 .. 0.91 5 ! 32.4 0.1 6.5e-09 5.3e-07 3 38 .] 231 267 .. 229 267 .. 0.94 6 ! 20.2 0.0 4.9e-05 0.004 10 37 .. 292 320 .. 284 320 .. 0.94 7 ! 13.9 0.0 0.0047 0.38 15 37 .. 338 360 .. 331 361 .. 0.92 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.38 EEEEEETTSSEEE CS WD40 14 tslafspdgawla 26 +s+afspdg+w+a sp|Q9NYS7|WSB2_HUMAN 30 WSVAFSPDGSWFA 42 79*********85 PP == domain 2 score: 10.9 bits; conditional E-value: 0.043 SSS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 Hss....vtslafspdgawlasGsdDgtvriW 37 H + v++l la+G Dg ++iW sp|Q9NYS7|WSB2_HUMAN 115 H-PqvpdVSCL-------VLATGLNDGQIKIW 138 4.233459999.......4478977******* PP == domain 3 score: 31.9 bits; conditional E-value: 9.5e-09 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 l l+GH++ v++l+f p+g+++ +s+s+D+t+riWd sp|Q9NYS7|WSB2_HUMAN 146 LLNLSGHQDvVRDLSFTPSGSLIlVSASRDKTLRIWD 182 56799**8857***********62589*********9 PP == domain 4 score: 22.2 bits; conditional E-value: 1.1e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 g+++++l+GH ++v++++ spd ++l+s+ + ++v +W+ sp|Q9NYS7|WSB2_HUMAN 187 GKQIQVLSGHlQWVYCCSISPDCSMLCSAaG-EKSVFLWS 225 57899*********************98735.*******5 PP == domain 5 score: 32.4 bits; conditional E-value: 6.5e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r+l+GH ssv s++fspd+a+l+++s+D +v +Wd sp|Q9NYS7|WSB2_HUMAN 231 LIRKLEGHqSSVVSCDFSPDSALLVTASYDTNVIMWD 267 6899****99999***********************9 PP == domain 6 score: 20.2 bits; conditional E-value: 4.9e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ss +s++fsp+g +la+ dD+ +riW sp|Q9NYS7|WSB2_HUMAN 292 HiSSLRSVCFSPEGLYLATVADDRLLRIW 320 88999*************9999******* PP == domain 7 score: 13.9 bits; conditional E-value: 0.0047 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ f p+g +a+G++Dg+v +W sp|Q9NYS7|WSB2_HUMAN 338 CCTFFPHGGVIATGTRDGHVQFW 360 788******************** PP >> tr|H0YN81|H0YN81_HUMAN WD repeat-containing protein 61 (Fragment) OS=Homo sapiens GN=WDR61 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.1 0.0088 0.72 9 38 .] 14 48 .. 6 48 .. 0.79 2 ! 19.1 0.4 0.00011 0.0087 3 38 .] 56 92 .. 54 92 .. 0.91 3 ? 9.9 0.0 0.084 6.8 14 29 .. 110 125 .. 96 131 .. 0.81 4 ! 20.2 0.0 4.8e-05 0.0039 11 38 .] 149 176 .. 138 176 .. 0.84 5 ! 38.0 0.0 1.1e-10 8.9e-09 1 38 [] 180 218 .. 180 218 .. 0.96 6 ! 30.8 1.5 2.2e-08 1.8e-06 5 38 .] 226 260 .. 222 260 .. 0.92 7 ? 9.3 0.2 0.13 11 2 29 .. 265 293 .. 264 294 .] 0.86 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0088 SS.SSEEEEEEETTSSE..........EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..........lasGsdDgtvriWd 38 +H + ++s+a w +++Gs D v++W+ tr|H0YN81|H0YN81_HUMAN 14 AHdDAIWSVA------WgtnkkensetVVTGSLDDLVKVWK 48 89555****5......5555555999999***********6 PP == domain 2 score: 19.1 bits; conditional E-value: 0.00011 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++l+GH +v s++ s+ + as+s D ++r+Wd tr|H0YN81|H0YN81_HUMAN 56 LQWSLEGHqLGVVSVDISHTLPIAASSSLDAHIRLWD 92 6899****76699**********99999********9 PP == domain 3 score: 9.9 bits; conditional E-value: 0.084 EEEEEETTSSEEEEEE CS WD40 14 tslafspdgawlasGs 29 + lafspd+++la+G+ tr|H0YN81|H0YN81_HUMAN 110 WTLAFSPDSQYLATGT 125 7899**********95 PP == domain 4 score: 20.2 bits; conditional E-value: 4.8e-05 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 +++ s+a+spdg++lasG Dg + i+d tr|H0YN81|H0YN81_HUMAN 149 KFILSIAYSPDGKYLASGAIDGIINIFD 176 5799**********************98 PP == domain 5 score: 38.0 bits; conditional E-value: 1.1e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l+tl+GH +++sl fspd+++l+++sdDg ++i+d tr|H0YN81|H0YN81_HUMAN 180 GKLLHTLEGHaMPIRSLTFSPDSQLLVTASDDGYIKIYD 218 689*******888*************************8 PP == domain 6 score: 30.8 bits; conditional E-value: 2.2e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tl+GH s+v +af+pd + ++s+s D++v++Wd tr|H0YN81|H0YN81_HUMAN 226 GTLSGHaSWVLNVAFCPDDTHFVSSSSDKSVKVWD 260 79****999*************99877*******9 PP == domain 7 score: 9.3 bits; conditional E-value: 0.13 EEEEEEESS.SSEEEEEEETTSSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs 29 +c++t+ H + v++++++ +g+ ++s + tr|H0YN81|H0YN81_HUMAN 265 TCVHTFFDHqDQVWGVKYNGNGSKIVSVG 293 79***999*666***********999866 PP >> tr|F5H280|F5H280_HUMAN WD repeat and SOCS box-containing protein 2 OS=Homo sapiens GN=WSB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.2 0.39 31 14 26 .. 32 44 .. 16 52 .. 0.83 2 ? 10.9 0.0 0.043 3.5 10 37 .. 117 140 .. 109 141 .. 0.73 3 ! 31.9 0.1 9.6e-09 7.7e-07 4 38 .] 148 184 .. 145 184 .. 0.87 4 ! 22.2 0.3 1.1e-05 0.0009 1 38 [] 189 227 .. 189 227 .. 0.91 5 ! 32.4 0.1 6.5e-09 5.3e-07 3 38 .] 233 269 .. 231 269 .. 0.94 6 ! 20.2 0.0 4.9e-05 0.004 10 37 .. 294 322 .. 286 322 .. 0.94 7 ! 13.9 0.0 0.0048 0.39 15 37 .. 340 362 .. 333 363 .. 0.92 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.39 EEEEEETTSSEEE CS WD40 14 tslafspdgawla 26 +s+afspdg+w+a tr|F5H280|F5H280_HUMAN 32 WSVAFSPDGSWFA 44 79*********85 PP == domain 2 score: 10.9 bits; conditional E-value: 0.043 SSS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 Hss....vtslafspdgawlasGsdDgtvriW 37 H + v++l la+G Dg ++iW tr|F5H280|F5H280_HUMAN 117 H-PqvpdVSCL-------VLATGLNDGQIKIW 140 4.233459999.......4478977******* PP == domain 3 score: 31.9 bits; conditional E-value: 9.6e-09 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 l l+GH++ v++l+f p+g+++ +s+s+D+t+riWd tr|F5H280|F5H280_HUMAN 148 LLNLSGHQDvVRDLSFTPSGSLIlVSASRDKTLRIWD 184 56799**8857***********62589*********9 PP == domain 4 score: 22.2 bits; conditional E-value: 1.1e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 g+++++l+GH ++v++++ spd ++l+s+ + ++v +W+ tr|F5H280|F5H280_HUMAN 189 GKQIQVLSGHlQWVYCCSISPDCSMLCSAaG-EKSVFLWS 227 57899*********************98735.*******5 PP == domain 5 score: 32.4 bits; conditional E-value: 6.5e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r+l+GH ssv s++fspd+a+l+++s+D +v +Wd tr|F5H280|F5H280_HUMAN 233 LIRKLEGHqSSVVSCDFSPDSALLVTASYDTNVIMWD 269 6899****99999***********************9 PP == domain 6 score: 20.2 bits; conditional E-value: 4.9e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ss +s++fsp+g +la+ dD+ +riW tr|F5H280|F5H280_HUMAN 294 HiSSLRSVCFSPEGLYLATVADDRLLRIW 322 88999*************9999******* PP == domain 7 score: 13.9 bits; conditional E-value: 0.0048 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ f p+g +a+G++Dg+v +W tr|F5H280|F5H280_HUMAN 340 CCTFFPHGGVIATGTRDGHVQFW 362 788******************** PP >> tr|B4DIE6|B4DIE6_HUMAN WD repeat and SOCS box-containing protein 2 OS=Homo sapiens GN=WSB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.2 0.4 33 14 26 .. 47 59 .. 31 67 .. 0.83 2 ? 10.8 0.0 0.045 3.6 10 37 .. 132 155 .. 124 156 .. 0.73 3 ! 31.8 0.1 1e-08 8.1e-07 4 38 .] 163 199 .. 160 199 .. 0.87 4 ! 22.1 0.3 1.2e-05 0.00094 1 38 [] 204 242 .. 204 242 .. 0.91 5 ! 32.4 0.1 6.8e-09 5.5e-07 3 38 .] 248 284 .. 246 284 .. 0.94 6 ! 20.1 0.0 5.2e-05 0.0042 10 37 .. 309 337 .. 301 337 .. 0.94 7 ! 13.8 0.0 0.005 0.41 15 37 .. 355 377 .. 348 378 .. 0.92 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.4 EEEEEETTSSEEE CS WD40 14 tslafspdgawla 26 +s+afspdg+w+a tr|B4DIE6|B4DIE6_HUMAN 47 WSVAFSPDGSWFA 59 79*********85 PP == domain 2 score: 10.8 bits; conditional E-value: 0.045 SSS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 Hss....vtslafspdgawlasGsdDgtvriW 37 H + v++l la+G Dg ++iW tr|B4DIE6|B4DIE6_HUMAN 132 H-PqvpdVSCL-------VLATGLNDGQIKIW 155 4.233359999.......4478977******* PP == domain 3 score: 31.8 bits; conditional E-value: 1e-08 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 l l+GH++ v++l+f p+g+++ +s+s+D+t+riWd tr|B4DIE6|B4DIE6_HUMAN 163 LLNLSGHQDvVRDLSFTPSGSLIlVSASRDKTLRIWD 199 56799**8857***********62589*********9 PP == domain 4 score: 22.1 bits; conditional E-value: 1.2e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 g+++++l+GH ++v++++ spd ++l+s+ + ++v +W+ tr|B4DIE6|B4DIE6_HUMAN 204 GKQIQVLSGHlQWVYCCSISPDCSMLCSAaG-EKSVFLWS 242 57899*********************98735.*******5 PP == domain 5 score: 32.4 bits; conditional E-value: 6.8e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r+l+GH ssv s++fspd+a+l+++s+D +v +Wd tr|B4DIE6|B4DIE6_HUMAN 248 LIRKLEGHqSSVVSCDFSPDSALLVTASYDTNVIMWD 284 6899****99999***********************9 PP == domain 6 score: 20.1 bits; conditional E-value: 5.2e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ss +s++fsp+g +la+ dD+ +riW tr|B4DIE6|B4DIE6_HUMAN 309 HiSSLRSVCFSPEGLYLATVADDRLLRIW 337 88999*************9999******* PP == domain 7 score: 13.8 bits; conditional E-value: 0.005 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ f p+g +a+G++Dg+v +W tr|B4DIE6|B4DIE6_HUMAN 355 CCTFFPHGGVIATGTRDGHVQFW 377 788******************** PP >> sp|O60336-2|MABP1_HUMAN Isoform 2 of Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens GN=MAPKBP1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 0.00037 0.03 10 38 .] 84 120 .. 75 120 .. 0.73 2 ! 13.5 0.0 0.0062 0.5 4 37 .. 127 163 .. 125 163 .. 0.79 3 ! 13.3 0.1 0.0073 0.59 12 37 .. 178 203 .. 168 203 .. 0.90 4 ! 13.1 0.1 0.0082 0.67 5 38 .] 273 300 .. 269 300 .. 0.70 5 ! 14.4 0.1 0.0033 0.27 15 38 .] 343 366 .. 319 366 .. 0.86 6 ! 13.4 0.1 0.0065 0.53 10 38 .] 382 421 .. 375 421 .. 0.72 7 ? 8.9 0.0 0.18 14 13 30 .. 476 493 .. 467 500 .. 0.83 8 ? 4.8 0.0 3.6 2.9e+02 7 36 .. 511 544 .. 503 546 .. 0.71 9 ? 10.8 0.0 0.045 3.6 3 36 .. 553 578 .. 551 589 .. 0.62 10 ? 8.1 0.0 0.32 26 15 38 .] 660 683 .. 642 683 .. 0.76 11 ! 17.0 0.3 0.00048 0.039 1 37 [. 687 724 .. 687 725 .. 0.88 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 0.00037 S..SS....EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 10 H..ss....vtslafspdgawlasG..sdDgtvriWd 38 H +s +t+lafspdg++l++G + + vr+Wd sp|O60336-2|MABP1_HUMAN 84 HilNSsrktITALAFSPDGKYLVTGesGHMPAVRVWD 120 455334666**************98654588888887 PP == domain 2 score: 13.5 bits; conditional E-value: 0.0062 EEEEESSSS.EEEEEEETTSSEEEEEET..TSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsd..DgtvriW 37 + +l H+ v ++afsp+ ++++s ++ D v +W sp|O60336-2|MABP1_HUMAN 127 VAELQEHKYgVACVAFSPSAKYIVSVGYqhDMIVNVW 163 5678889455************99755223**99999 PP == domain 3 score: 13.3 bits; conditional E-value: 0.0073 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 s vt+++fs d +++++++ ++++++W sp|O60336-2|MABP1_HUMAN 178 SrVTAVSFSEDCSYFVTAG-NRHIKFW 203 349****************.******* PP == domain 4 score: 13.1 bits; conditional E-value: 0.0082 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 rt +H ++ s +++++++G+ Dgtvr+++ sp|O60336-2|MABP1_HUMAN 273 RTTVAH-CI-----SVSQDYIFCGCADGTVRLFN 300 555566.44.....335588889*99******97 PP == domain 5 score: 14.4 bits; conditional E-value: 0.0033 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +l f+p ++wl++ D+++++Wd sp|O60336-2|MABP1_HUMAN 343 ALTFDPTNQWLSCVYNDHSIYVWD 366 677*******965578*******9 PP == domain 6 score: 13.4 bits; conditional E-value: 0.0065 S.SSEEEEE...........EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla...........fspdgawlasGsdDgtvriWd 38 H s+v+s+ p +++++++s D+t+r+W+ sp|O60336-2|MABP1_HUMAN 382 HsSCVWSVEvypevkdsnqaCLPPSSFITCSS-DNTIRLWN 421 54446666666666666666778888887666.*******8 PP == domain 7 score: 8.9 bits; conditional E-value: 0.18 EEEEEEETTSSEEEEEET CS WD40 13 vtslafspdgawlasGsd 30 ++s+++sp+g+ lasG++ sp|O60336-2|MABP1_HUMAN 476 IRSVCVSPNGQHLASGDR 493 89***********98864 PP == domain 8 score: 4.8 bits; conditional E-value: 3.6 EESS.SSEEEEE...EETTSSE...EEEEETTSEEEE CS WD40 7 ltGH.ssvtsla...fspdgaw...lasGsdDgtvri 36 ++H s + +l + las+s+D+ +++ sp|O60336-2|MABP1_HUMAN 511 VEAHdSEILCLEyskPDT---GlklLASASRDRLIHV 544 579966699997533333...24558999****9987 PP == domain 9 score: 10.8 bits; conditional E-value: 0.045 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++tl+ H ss+t+++ + ++s Dg vr+ sp|O60336-2|MABP1_HUMAN 553 LQQTLDEHsSSITAVK------F--AAS-DGQVRM 578 7899****888****4......4..344.444443 PP == domain 10 score: 8.1 bits; conditional E-value: 0.32 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++++p+g ++a+++ D+++ i+d sp|O60336-2|MABP1_HUMAN 660 KVQTDPSGIYIATSCSDKNLSIFD 683 6789*******96644*****998 PP == domain 11 score: 17.0 bits; conditional E-value: 0.00048 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+c+ t GHs vt+++fs d + l+s s D + +W sp|O60336-2|MABP1_HUMAN 687 GECVATMFGHSEiVTGMKFSNDCKHLISVSGDSCIFVW 724 68999999**6657************98766******* PP >> tr|B4DF38|B4DF38_HUMAN Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens GN=PAFAH1B1 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.0 0.1 2.1e-09 1.7e-07 2 37 .. 12 48 .. 11 49 .. 0.93 2 ! 31.4 0.1 1.4e-08 1.1e-06 2 37 .. 54 90 .. 53 91 .. 0.96 3 ? 8.9 0.0 0.17 14 2 25 .. 96 120 .. 95 129 .. 0.77 4 ! 29.5 1.4 5.6e-08 4.5e-06 9 38 .] 131 161 .. 123 161 .. 0.93 5 ! 35.1 0.0 9.4e-10 7.6e-08 2 37 .. 166 202 .. 165 203 .. 0.93 Alignments for each domain: == domain 1 score: 34.0 bits; conditional E-value: 2.1e-09 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +c+rt GH++ v+s+a p+g+ ++s+s+D+t+++W tr|B4DF38|B4DF38_HUMAN 12 ECIRTMHGHDHnVSSVAIMPNGDHIVSASRDKTIKMW 48 8********556************************* PP == domain 2 score: 31.4 bits; conditional E-value: 1.4e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++t+tGH +v+ ++ ++dg+++as+s D+tvr+W tr|B4DF38|B4DF38_HUMAN 54 YCVKTFTGHrEWVRMVRPNQDGTLIASCSNDQTVRVW 90 69*******999************************* PP == domain 3 score: 8.9 bits; conditional E-value: 0.17 EEEEEEESSSS.EEEEEEETTSSEE CS WD40 2 qclrtltGHss.vtslafspdgawl 25 +c +l+ H + v ++++ p++++ tr|B4DF38|B4DF38_HUMAN 96 ECKAELREHEHvVECISWAPESSYS 120 688999***8867*********992 PP == domain 4 score: 29.5 bits; conditional E-value: 5.6e-08 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++v+++ f++ g++++s+ dD+t+r+Wd tr|B4DF38|B4DF38_HUMAN 131 GHdNWVRGVLFHSGGKFILSCADDKTLRVWD 161 9*999*************************9 PP == domain 5 score: 35.1 bits; conditional E-value: 9.4e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +c++tl +H +vtsl+f++ +++++Gs D+tv++W tr|B4DF38|B4DF38_HUMAN 166 RCMKTLNAHeHFVTSLDFHKTAPYVVTGSVDQTVKVW 202 79*******666************************* PP >> sp|O75083-3|WDR1_HUMAN Isoform 2 of WD repeat-containing protein 1 OS=Homo sapiens GN=WDR1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.7 0.1 4.3e-07 3.5e-05 4 38 .] 42 77 .. 39 77 .. 0.87 2 ! 25.4 1.2 1.1e-06 9.1e-05 8 38 .] 91 122 .. 83 122 .. 0.90 3 ! 22.9 1.4 6.9e-06 0.00056 2 38 .] 171 210 .. 170 210 .. 0.91 4 ? 11.8 0.1 0.021 1.7 8 35 .. 222 249 .. 216 250 .. 0.89 5 ? 11.4 0.0 0.029 2.4 16 37 .. 311 332 .. 297 333 .. 0.88 6 ? 10.1 0.0 0.076 6.2 11 32 .. 350 371 .. 341 377 .. 0.80 7 ! 27.1 0.1 3.2e-07 2.6e-05 6 37 .. 387 419 .. 383 420 .. 0.89 8 ? 8.9 0.5 0.18 15 9 37 .. 433 462 .. 426 463 .. 0.82 Alignments for each domain: == domain 1 score: 26.7 bits; conditional E-value: 4.3e-07 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 lr ++ Hs v++++fspdg+ +a++s Dg ++i+d sp|O75083-3|WDR1_HUMAN 42 LRNIDDHSRfVNCVRFSPDGNRFATASADGQIYIYD 77 5667789445************************98 PP == domain 2 score: 25.4 bits; conditional E-value: 1.1e-06 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++H ++++++++spd++ l+s+s D+t +iWd sp|O75083-3|WDR1_HUMAN 91 KAHdGGIYAISWSPDSTHLLSASGDKTSKIWD 122 589777*************99988*******9 PP == domain 3 score: 22.9 bits; conditional E-value: 6.9e-06 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 ++l++++GH +s+ +l ++++g + sGs Dg++ Wd sp|O75083-3|WDR1_HUMAN 171 KPLHVIKGHsKSIQCLTVHKNGGKsyIYSGSHDGHINYWD 210 79*******999*****88888887799**99*******9 PP == domain 4 score: 11.8 bits; conditional E-value: 0.021 ESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvr 35 +GH + v+ + ++ +g+++ s+s+D tvr sp|O75083-3|WDR1_HUMAN 222 KGHtNQVSRMTVDESGQLI-SCSMDDTVR 249 7**988************8.6888***98 PP == domain 5 score: 11.4 bits; conditional E-value: 0.029 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +a++p g+ +a G+ Dg+vr++ sp|O75083-3|WDR1_HUMAN 311 VAVHPGGDTVAIGGVDGNVRLY 332 457*****************98 PP == domain 6 score: 10.1 bits; conditional E-value: 0.076 SSEEEEEEETTSSEEEEEETTS CS WD40 11 ssvtslafspdgawlasGsdDg 32 ++vt++a+s+dga+la ++ + sp|O75083-3|WDR1_HUMAN 350 GPVTDVAYSHDGAFLAVCDASK 371 45*************9986555 PP == domain 7 score: 27.1 bits; conditional E-value: 3.2e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++ GH + +la+spd+ +asG++D v++W sp|O75083-3|WDR1_HUMAN 387 VFYGHhAKIVCLAWSPDNEHFASGGMDMMVYVW 419 6789966699*********************** PP == domain 8 score: 8.9 bits; conditional E-value: 0.18 SS..SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH..ssvtslafspdgawlasGsdDgtvriW 37 +H +v+sla+ ++++++++++ D +v+ W sp|O75083-3|WDR1_HUMAN 433 AHrlHHVSSLAWLDEHTLVTTSH-DASVKEW 462 555446************99989.****977 PP >> tr|F5GYK2|F5GYK2_HUMAN Striatin-4 OS=Homo sapiens GN=STRN4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.1 4.7e-07 3.8e-05 1 38 [] 309 347 .. 309 347 .. 0.94 2 ? 11.8 0.0 0.022 1.8 2 38 .] 363 400 .. 362 400 .. 0.94 3 ! 39.9 0.4 2.9e-11 2.4e-09 4 38 .] 418 453 .. 415 453 .. 0.92 4 ? 4.9 0.0 3.3 2.7e+02 12 36 .. 517 544 .. 504 546 .. 0.79 5 ! 37.4 0.1 1.8e-10 1.5e-08 1 38 [] 550 588 .. 550 588 .. 0.96 6 ? 12.7 0.0 0.012 0.94 2 32 .. 593 628 .. 592 633 .. 0.85 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 4.7e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ tl+ H ++++slaf+++++ l+++s+Dgt+++W+ tr|F5GYK2|F5GYK2_HUMAN 309 WNPKFTLRSHyDGIRSLAFHHSQSALLTASEDGTLKLWN 347 578899****999*************************8 PP == domain 2 score: 11.8 bits; conditional E-value: 0.022 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +++H ++v ++a +++ + sG+ D ++ W+ tr|F5GYK2|F5GYK2_HUMAN 363 EPIHAFRAHrGPVLAVAMGSNSEYCYSGGADACIHSWK 400 5899*****999**********************9995 PP == domain 3 score: 39.9 bits; conditional E-value: 2.9e-11 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH + v++lafsp ++ las+s DgtvriWd tr|F5GYK2|F5GYK2_HUMAN 418 SHVLEGHgDAVWGLAFSPTSQRLASCSADGTVRIWD 453 699****666*************************9 PP == domain 4 score: 4.9 bits; conditional E-value: 3.3 S...EEEEEEETTSSEEEEEETTSEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvri 36 + ++ + +p++++ ++++dD+ +r+ tr|F5GYK2|F5GYK2_HUMAN 517 GptqINQVVSHPNQPLTITAHDDRGIRF 544 2356999*********889*****9996 PP == domain 5 score: 37.4 bits; conditional E-value: 1.8e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+++++ +H + vt+la++p+ga+l+sGs D+++r+W+ tr|F5GYK2|F5GYK2_HUMAN 550 GKPVHSMVAHlDAVTCLAVDPNGAFLMSGSHDCSLRLWS 588 689*******999****************99*******5 PP == domain 6 score: 12.7 bits; conditional E-value: 0.012 EEEEEEESS..SS...EEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGH..ss...vtslafspdgawlasGsdDg 32 +c++++t+H ++ ++++a +p++a++as++ D tr|F5GYK2|F5GYK2_HUMAN 593 TCVQEITAHrkKHeeaIHAVACHPSKALIASAGADA 628 699999***9655999**************998886 PP >> sp|O60336|MABP1_HUMAN Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens GN=MAPKBP1 PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 0.00047 0.038 10 38 .] 84 120 .. 75 120 .. 0.73 2 ! 13.2 0.0 0.0078 0.64 4 37 .. 127 163 .. 125 163 .. 0.79 3 ! 13.0 0.1 0.0092 0.75 12 37 .. 178 203 .. 168 203 .. 0.90 4 ! 12.9 0.1 0.0098 0.8 13 38 .] 282 306 .. 272 306 .. 0.69 5 ! 14.1 0.1 0.0041 0.33 15 38 .] 349 372 .. 326 372 .. 0.87 6 ! 13.1 0.1 0.0083 0.67 10 38 .] 388 427 .. 381 427 .. 0.72 7 ? 8.6 0.0 0.22 18 13 30 .. 482 499 .. 473 506 .. 0.83 8 ? 4.4 0.0 4.6 3.7e+02 7 36 .. 517 550 .. 509 552 .. 0.71 9 ? 10.5 0.0 0.056 4.6 3 36 .. 559 584 .. 557 595 .. 0.63 10 ? 7.8 0.0 0.4 32 15 38 .] 666 689 .. 648 689 .. 0.76 11 ! 16.7 0.3 0.00061 0.049 1 37 [. 693 730 .. 693 731 .. 0.88 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 0.00047 S..SS....EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 10 H..ss....vtslafspdgawlasG..sdDgtvriWd 38 H +s +t+lafspdg++l++G + + vr+Wd sp|O60336|MABP1_HUMAN 84 HilNSsrktITALAFSPDGKYLVTGesGHMPAVRVWD 120 455334666**************98654588888887 PP == domain 2 score: 13.2 bits; conditional E-value: 0.0078 EEEEESSSS.EEEEEEETTSSEEEEEET..TSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsd..DgtvriW 37 + +l H+ v ++afsp+ ++++s ++ D v +W sp|O60336|MABP1_HUMAN 127 VAELQEHKYgVACVAFSPSAKYIVSVGYqhDMIVNVW 163 5678889455************99755223**99999 PP == domain 3 score: 13.0 bits; conditional E-value: 0.0092 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 s vt+++fs d +++++++ ++++++W sp|O60336|MABP1_HUMAN 178 SrVTAVSFSEDCSYFVTAG-NRHIKFW 203 349****************.******* PP == domain 4 score: 12.9 bits; conditional E-value: 0.0098 E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 v.tslafspdgawlasGsdDgtvriWd 38 v +++ s +++++++G+ Dgtvr+++ sp|O60336|MABP1_HUMAN 282 VaHCI--SVSQDYIFCGCADGTVRLFN 306 54566..445577779*99******97 PP == domain 5 score: 14.1 bits; conditional E-value: 0.0041 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +l f+p ++wl++ D+++++Wd sp|O60336|MABP1_HUMAN 349 ALTFDPTNQWLSCVYNDHSIYVWD 372 677*******965578*******9 PP == domain 6 score: 13.1 bits; conditional E-value: 0.0083 S.SSEEEEE...........EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla...........fspdgawlasGsdDgtvriWd 38 H s+v+s+ p +++++++s D+t+r+W+ sp|O60336|MABP1_HUMAN 388 HsSCVWSVEvypevkdsnqaCLPPSSFITCSS-DNTIRLWN 427 54446666666666656666778888887666.*******8 PP == domain 7 score: 8.6 bits; conditional E-value: 0.22 EEEEEEETTSSEEEEEET CS WD40 13 vtslafspdgawlasGsd 30 ++s+++sp+g+ lasG++ sp|O60336|MABP1_HUMAN 482 IRSVCVSPNGQHLASGDR 499 89***********98864 PP == domain 8 score: 4.4 bits; conditional E-value: 4.6 EESS.SSEEEEE...EETTSSE...EEEEETTSEEEE CS WD40 7 ltGH.ssvtsla...fspdgaw...lasGsdDgtvri 36 ++H s + +l + las+s+D+ +++ sp|O60336|MABP1_HUMAN 517 VEAHdSEILCLEyskPDT---GlklLASASRDRLIHV 550 579966699997533333...24558999****9987 PP == domain 9 score: 10.5 bits; conditional E-value: 0.056 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++tl+ H ss+t+++ + ++s Dg vr+ sp|O60336|MABP1_HUMAN 559 LQQTLDEHsSSITAVK------F--AAS-DGQVRM 584 7899****888****4......4..344.444443 PP == domain 10 score: 7.8 bits; conditional E-value: 0.4 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++++p+g ++a+++ D+++ i+d sp|O60336|MABP1_HUMAN 666 KVQTDPSGIYIATSCSDKNLSIFD 689 6789*******96644*****998 PP == domain 11 score: 16.7 bits; conditional E-value: 0.00061 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+c+ t GHs vt+++fs d + l+s s D + +W sp|O60336|MABP1_HUMAN 693 GECVATMFGHSEiVTGMKFSNDCKHLISVSGDSCIFVW 730 68999999**6657************98766******* PP >> tr|E5RIM3|E5RIM3_HUMAN Phospholipase A-2-activating protein OS=Homo sapiens GN=PLAA PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.052 4.2 5 37 .. 12 46 .. 8 46 .. 0.75 2 ! 18.5 0.6 0.00017 0.013 3 37 .. 57 97 .. 55 98 .. 0.89 3 ! 22.6 0.2 8.3e-06 0.00068 3 37 .. 104 138 .. 103 138 .. 0.93 4 ! 27.5 0.0 2.3e-07 1.9e-05 2 38 .] 142 179 .. 141 179 .. 0.94 5 ! 15.9 0.0 0.0011 0.09 1 37 [. 181 217 .. 181 218 .. 0.89 6 ! 21.3 0.0 2.2e-05 0.0018 1 38 [] 221 259 .. 221 259 .. 0.81 7 ! 14.0 0.1 0.0045 0.36 9 37 .. 271 297 .. 261 298 .. 0.77 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.052 EEEESS.SS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ss....vtslafspdgawlasGsdDgtvriW 37 +l+GH + v++ p ga++ s s+D+t r+W tr|E5RIM3|E5RIM3_HUMAN 12 CSLRGHeLDvrglVCCA--YPPGAFV-SVSRDRTTRLW 46 5799**75545556555..8888997.5788******* PP == domain 2 score: 18.5 bits; conditional E-value: 0.00017 EEEEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 ++ +GH ++v++++ p+++ +a+G+ D+++ i+ tr|E5RIM3|E5RIM3_HUMAN 57 EMHCMSGHsNFVSCVCIIPSSDIyphglIATGGNDHNICIF 97 578899**888*****99999999999889********997 PP == domain 3 score: 22.6 bits; conditional E-value: 8.3e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l++l+GH + v+sl+ + g++l sGs+D t ++W tr|E5RIM3|E5RIM3_HUMAN 104 PLYILKGHkNTVCSLSSGKFGTLL-SGSWDTTAKVW 138 6899****888****999999998.7********** PP == domain 4 score: 27.5 bits; conditional E-value: 2.3e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ tl GH v++++ p++ ++++Gs D+tv++W+ tr|E5RIM3|E5RIM3_HUMAN 142 KCMMTLQGHtAAVWAVKILPEQGLMLTGSADKTVKLWK 179 79*******777*************************6 PP == domain 5 score: 15.9 bits; conditional E-value: 0.0011 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+c rt++GH ++v++la ++ +l+ + D ++r W tr|E5RIM3|E5RIM3_HUMAN 181 GRCERTFSGHeDCVRGLAILSETEFLS-CANDASIRRW 217 689*******888************96.666****988 PP == domain 6 score: 21.3 bits; conditional E-value: 2.2e-05 TEEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 g+cl ++ GH + ++s++ f+ +++ + +D+++riW+ tr|E5RIM3|E5RIM3_HUMAN 221 GECLEVYYGHtNYIYSISvFPNCRDFV-TTAEDRSLRIWK 259 68********888*****666666665.5566*******6 PP == domain 7 score: 14.0 bits; conditional E-value: 0.0045 SSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriW 37 ++ s++++++ ++g+ ++ +s Dg +r++ tr|E5RIM3|E5RIM3_HUMAN 271 AQ-SIWCCCVLDNGDIVVGAS-DGIIRVF 297 55.8************99447.*****96 PP >> sp|O60336-6|MABP1_HUMAN Isoform 6 of Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens GN=MAPKBP1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 0.00046 0.038 10 38 .] 84 120 .. 75 120 .. 0.73 2 ! 13.2 0.0 0.0078 0.63 4 37 .. 127 163 .. 125 163 .. 0.79 3 ! 13.0 0.1 0.0092 0.75 12 37 .. 178 203 .. 168 203 .. 0.90 4 ? 12.8 0.1 0.01 0.84 5 38 .] 273 300 .. 269 300 .. 0.70 5 ! 14.1 0.1 0.0041 0.33 15 38 .] 343 366 .. 320 366 .. 0.87 6 ! 13.1 0.1 0.0082 0.67 10 38 .] 382 421 .. 375 421 .. 0.72 7 ? 8.6 0.0 0.22 18 13 30 .. 476 493 .. 467 500 .. 0.83 8 ? 4.4 0.0 4.6 3.7e+02 7 36 .. 511 544 .. 503 546 .. 0.71 9 ? 10.5 0.0 0.056 4.5 3 36 .. 553 578 .. 551 589 .. 0.63 10 ? 7.8 0.0 0.4 32 15 38 .] 660 683 .. 642 683 .. 0.76 11 ! 16.7 0.3 0.0006 0.049 1 37 [. 687 724 .. 687 725 .. 0.88 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 0.00046 S..SS....EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 10 H..ss....vtslafspdgawlasG..sdDgtvriWd 38 H +s +t+lafspdg++l++G + + vr+Wd sp|O60336-6|MABP1_HUMAN 84 HilNSsrktITALAFSPDGKYLVTGesGHMPAVRVWD 120 455334666**************98654588888887 PP == domain 2 score: 13.2 bits; conditional E-value: 0.0078 EEEEESSSS.EEEEEEETTSSEEEEEET..TSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsd..DgtvriW 37 + +l H+ v ++afsp+ ++++s ++ D v +W sp|O60336-6|MABP1_HUMAN 127 VAELQEHKYgVACVAFSPSAKYIVSVGYqhDMIVNVW 163 5678889455************99755223**99999 PP == domain 3 score: 13.0 bits; conditional E-value: 0.0092 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 s vt+++fs d +++++++ ++++++W sp|O60336-6|MABP1_HUMAN 178 SrVTAVSFSEDCSYFVTAG-NRHIKFW 203 349****************.******* PP == domain 4 score: 12.8 bits; conditional E-value: 0.01 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 rt +H ++ s +++++++G+ Dgtvr+++ sp|O60336-6|MABP1_HUMAN 273 RTTVAH-CI-----SVSQDYIFCGCADGTVRLFN 300 555566.44.....335588889*99******97 PP == domain 5 score: 14.1 bits; conditional E-value: 0.0041 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +l f+p ++wl++ D+++++Wd sp|O60336-6|MABP1_HUMAN 343 ALTFDPTNQWLSCVYNDHSIYVWD 366 677*******965578*******9 PP == domain 6 score: 13.1 bits; conditional E-value: 0.0082 S.SSEEEEE...........EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla...........fspdgawlasGsdDgtvriWd 38 H s+v+s+ p +++++++s D+t+r+W+ sp|O60336-6|MABP1_HUMAN 382 HsSCVWSVEvypevkdsnqaCLPPSSFITCSS-DNTIRLWN 421 54446666666666656666778888887666.*******8 PP == domain 7 score: 8.6 bits; conditional E-value: 0.22 EEEEEEETTSSEEEEEET CS WD40 13 vtslafspdgawlasGsd 30 ++s+++sp+g+ lasG++ sp|O60336-6|MABP1_HUMAN 476 IRSVCVSPNGQHLASGDR 493 89***********98864 PP == domain 8 score: 4.4 bits; conditional E-value: 4.6 EESS.SSEEEEE...EETTSSE...EEEEETTSEEEE CS WD40 7 ltGH.ssvtsla...fspdgaw...lasGsdDgtvri 36 ++H s + +l + las+s+D+ +++ sp|O60336-6|MABP1_HUMAN 511 VEAHdSEILCLEyskPDT---GlklLASASRDRLIHV 544 579966699997533333...24558999****9987 PP == domain 9 score: 10.5 bits; conditional E-value: 0.056 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++tl+ H ss+t+++ + ++s Dg vr+ sp|O60336-6|MABP1_HUMAN 553 LQQTLDEHsSSITAVK------F--AAS-DGQVRM 578 7899****888****4......4..344.444443 PP == domain 10 score: 7.8 bits; conditional E-value: 0.4 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++++p+g ++a+++ D+++ i+d sp|O60336-6|MABP1_HUMAN 660 KVQTDPSGIYIATSCSDKNLSIFD 683 6789*******96644*****998 PP == domain 11 score: 16.7 bits; conditional E-value: 0.0006 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+c+ t GHs vt+++fs d + l+s s D + +W sp|O60336-6|MABP1_HUMAN 687 GECVATMFGHSEiVTGMKFSNDCKHLISVSGDSCIFVW 724 68999999**6657************98766******* PP >> tr|D6RHH4|D6RHH4_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 0.0001 0.0084 4 38 .] 8 44 .. 5 44 .. 0.87 2 ! 36.3 0.6 3.8e-10 3.1e-08 3 38 .] 55 91 .. 53 91 .. 0.93 3 ! 36.7 0.2 2.8e-10 2.3e-08 3 38 .] 97 133 .. 95 133 .. 0.93 4 ! 25.0 1.0 1.5e-06 0.00012 9 38 .] 146 178 .. 136 178 .. 0.83 5 ! 19.2 0.1 9.6e-05 0.0078 7 37 .. 188 226 .. 182 227 .. 0.79 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 0.0001 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s+s+D+t+ +W+ tr|D6RHH4|D6RHH4_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRDKTIIMWK 44 5799***666****99888888899***********6 PP == domain 2 score: 36.3 bits; conditional E-value: 3.8e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6RHH4|D6RHH4_HUMAN 55 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 91 7899****667************99***********9 PP == domain 3 score: 36.7 bits; conditional E-value: 2.8e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|D6RHH4|D6RHH4_HUMAN 97 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133 678899******************************8 PP == domain 4 score: 25.0 bits; conditional E-value: 1.5e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|D6RHH4|D6RHH4_HUMAN 146 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 178 79666*************989***********8 PP == domain 5 score: 19.2 bits; conditional E-value: 9.6e-05 EESS.SSEEEEEEETTSSEEEEEET.......TSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsd.......DgtvriW 37 GH + + + +spdg++ asG++ D+ vr+W tr|D6RHH4|D6RHH4_HUMAN 188 HIGHtGYLNTVTVSPDGSLCASGGKtlfagytDNLVRVW 226 3499666************8888766667777******* PP >> sp|O14775-2|GBB5_HUMAN Isoform 2 of Guanine nucleotide-binding protein subunit beta-5 OS=Homo sapiens GN=GNB5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.4 0.2 6e-08 4.9e-06 3 38 .] 55 91 .. 53 91 .. 0.93 2 ? 5.5 0.0 2.1 1.7e+02 12 37 .. 107 132 .. 93 132 .. 0.81 3 ? 9.1 0.1 0.16 13 13 38 .] 156 181 .. 146 181 .. 0.64 4 ! 23.9 0.1 3.2e-06 0.00026 1 38 [] 185 225 .. 185 225 .. 0.91 5 ! 29.1 0.0 7.2e-08 5.8e-06 1 38 [] 229 267 .. 229 267 .. 0.97 6 ! 13.3 0.1 0.0074 0.6 14 38 .] 287 311 .. 277 311 .. 0.91 7 ! 27.4 0.7 2.5e-07 2e-05 4 37 .. 318 352 .. 315 352 .. 0.91 Alignments for each domain: == domain 1 score: 29.4 bits; conditional E-value: 6e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + rtl+GH + v ++++++d++ ++s+s Dg+v +Wd sp|O14775-2|GBB5_HUMAN 55 TRRTLKGHgNKVLCMDWCKDKRRIVSSSQDGKVIVWD 91 6799****888*************************9 PP == domain 2 score: 5.5 bits; conditional E-value: 2.1 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +v ++a+ p+g +a+G+ D+++ ++ sp|O14775-2|GBB5_HUMAN 107 WVMACAYAPSGCAIACGGLDNKCSVY 132 488999************9*999875 PP == domain 3 score: 9.1 bits; conditional E-value: 0.16 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++f + ++++s Dgt+ +Wd sp|O14775-2|GBB5_HUMAN 156 LSACSFTNSDMQILTASGDGTCALWD 181 555554444444555544*******9 PP == domain 4 score: 23.9 bits; conditional E-value: 3.2e-06 TEEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 gq+l+++ GH +v +l+ s g+ ++sG+ D++ ++Wd sp|O14775-2|GBB5_HUMAN 185 GQLLQSFHGHgADVLCLDlaPSETGNTFVSGGCDKKAMVWD 225 689*******888988888899999999***88*******9 PP == domain 5 score: 29.1 bits; conditional E-value: 7.2e-08 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqc++ +++H s+++s+++ p+g+ +asGsdD t+r++d sp|O14775-2|GBB5_HUMAN 229 GQCVQAFETHeSDINSVRYYPSGDAFASGSDDATCRLYD 267 79********999************************98 PP == domain 6 score: 13.3 bits; conditional E-value: 0.0074 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 +s++fs +g++l++G D t+ +Wd sp|O14775-2|GBB5_HUMAN 287 SSVDFSLSGRLLFAGYNDYTINVWD 311 5899999********99*******9 PP == domain 7 score: 27.4 bits; conditional E-value: 2.5e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l GH + v+ l++spdg+ ++sGs+D+t+r+W sp|O14775-2|GBB5_HUMAN 318 VSILFGHeNRVSTLRVSPDGTAFCSGSWDHTLRVW 352 56777**999************************* PP >> sp|Q9NRL3|STRN4_HUMAN Striatin-4 OS=Homo sapiens GN=STRN4 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.1 5.8e-07 4.7e-05 1 38 [] 428 466 .. 428 466 .. 0.94 2 ? 11.5 0.0 0.027 2.2 2 38 .] 482 519 .. 481 519 .. 0.94 3 ! 39.6 0.4 3.6e-11 2.9e-09 4 38 .] 537 572 .. 534 572 .. 0.92 4 ? 4.6 0.0 4.1 3.3e+02 12 36 .. 636 663 .. 623 665 .. 0.79 5 ! 37.1 0.1 2.2e-10 1.8e-08 1 38 [] 669 707 .. 669 707 .. 0.96 6 ? 12.4 0.0 0.014 1.2 2 32 .. 712 747 .. 711 752 .. 0.85 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 5.8e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ tl+ H ++++slaf+++++ l+++s+Dgt+++W+ sp|Q9NRL3|STRN4_HUMAN 428 WNPKFTLRSHyDGIRSLAFHHSQSALLTASEDGTLKLWN 466 578899****999*************************8 PP == domain 2 score: 11.5 bits; conditional E-value: 0.027 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +++H ++v ++a +++ + sG+ D ++ W+ sp|Q9NRL3|STRN4_HUMAN 482 EPIHAFRAHrGPVLAVAMGSNSEYCYSGGADACIHSWK 519 5899*****999**********************9995 PP == domain 3 score: 39.6 bits; conditional E-value: 3.6e-11 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH + v++lafsp ++ las+s DgtvriWd sp|Q9NRL3|STRN4_HUMAN 537 SHVLEGHgDAVWGLAFSPTSQRLASCSADGTVRIWD 572 699****666*************************9 PP == domain 4 score: 4.6 bits; conditional E-value: 4.1 S...EEEEEEETTSSEEEEEETTSEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvri 36 + ++ + +p++++ ++++dD+ +r+ sp|Q9NRL3|STRN4_HUMAN 636 GptqINQVVSHPNQPLTITAHDDRGIRF 663 2356999*********889*****9996 PP == domain 5 score: 37.1 bits; conditional E-value: 2.2e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+++++ +H + vt+la++p+ga+l+sGs D+++r+W+ sp|Q9NRL3|STRN4_HUMAN 669 GKPVHSMVAHlDAVTCLAVDPNGAFLMSGSHDCSLRLWS 707 689*******999****************99*******5 PP == domain 6 score: 12.4 bits; conditional E-value: 0.014 EEEEEEESS..SS...EEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGH..ss...vtslafspdgawlasGsdDg 32 +c++++t+H ++ ++++a +p++a++as++ D sp|Q9NRL3|STRN4_HUMAN 712 TCVQEITAHrkKHeeaIHAVACHPSKALIASAGADA 747 699999***9655999**************998886 PP >> tr|F8VYA6|F8VYA6_HUMAN Striatin-4 OS=Homo sapiens GN=STRN4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.1 5.8e-07 4.7e-05 1 38 [] 435 473 .. 435 473 .. 0.94 2 ? 11.5 0.0 0.027 2.2 2 38 .] 489 526 .. 488 526 .. 0.94 3 ! 39.6 0.4 3.6e-11 2.9e-09 4 38 .] 544 579 .. 541 579 .. 0.92 4 ? 4.6 0.0 4.1 3.3e+02 12 36 .. 643 670 .. 630 672 .. 0.79 5 ! 37.1 0.1 2.2e-10 1.8e-08 1 38 [] 676 714 .. 676 714 .. 0.96 6 ? 12.4 0.0 0.014 1.2 2 32 .. 719 754 .. 718 759 .. 0.85 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 5.8e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ tl+ H ++++slaf+++++ l+++s+Dgt+++W+ tr|F8VYA6|F8VYA6_HUMAN 435 WNPKFTLRSHyDGIRSLAFHHSQSALLTASEDGTLKLWN 473 578899****999*************************8 PP == domain 2 score: 11.5 bits; conditional E-value: 0.027 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +++H ++v ++a +++ + sG+ D ++ W+ tr|F8VYA6|F8VYA6_HUMAN 489 EPIHAFRAHrGPVLAVAMGSNSEYCYSGGADACIHSWK 526 5899*****999**********************9995 PP == domain 3 score: 39.6 bits; conditional E-value: 3.6e-11 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH + v++lafsp ++ las+s DgtvriWd tr|F8VYA6|F8VYA6_HUMAN 544 SHVLEGHgDAVWGLAFSPTSQRLASCSADGTVRIWD 579 699****666*************************9 PP == domain 4 score: 4.6 bits; conditional E-value: 4.1 S...EEEEEEETTSSEEEEEETTSEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvri 36 + ++ + +p++++ ++++dD+ +r+ tr|F8VYA6|F8VYA6_HUMAN 643 GptqINQVVSHPNQPLTITAHDDRGIRF 670 2356999*********889*****9996 PP == domain 5 score: 37.1 bits; conditional E-value: 2.2e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+++++ +H + vt+la++p+ga+l+sGs D+++r+W+ tr|F8VYA6|F8VYA6_HUMAN 676 GKPVHSMVAHlDAVTCLAVDPNGAFLMSGSHDCSLRLWS 714 689*******999****************99*******5 PP == domain 6 score: 12.4 bits; conditional E-value: 0.014 EEEEEEESS..SS...EEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGH..ss...vtslafspdgawlasGsdDg 32 +c++++t+H ++ ++++a +p++a++as++ D tr|F8VYA6|F8VYA6_HUMAN 719 TCVQEITAHrkKHeeaIHAVACHPSKALIASAGADA 754 699999***9655999**************998886 PP >> tr|B4DZI8|B4DZI8_HUMAN Coatomer protein complex, subunit beta 2 (Beta prime), isoform CRA_b OS=Homo sapiens GN=COPB2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.16 13 13 38 .] 31 56 .. 18 56 .. 0.81 2 ! 28.4 0.0 1.2e-07 1e-05 4 38 .] 63 98 .. 60 98 .. 0.92 3 ! 18.2 0.1 0.0002 0.016 1 37 [. 103 141 .. 103 142 .. 0.86 4 ! 27.7 0.0 2.1e-07 1.7e-05 3 38 .] 148 186 .. 146 186 .. 0.91 5 ! 35.5 0.1 7.1e-10 5.7e-08 2 37 .. 191 227 .. 190 228 .. 0.95 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.16 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v++ +f ++w+++G dD +r+++ tr|B4DZI8|B4DZI8_HUMAN 31 VRAAKFVARKNWVVTGADDMQIRVFN 56 6777788899**************97 PP == domain 2 score: 28.4 bits; conditional E-value: 1.2e-07 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ +++Hs+ ++++a++p +++++++sdD +++Wd tr|B4DZI8|B4DZI8_HUMAN 63 VHMFEAHSDyIRCIAVHPTQPFILTSSDDMLIKLWD 98 799****556*************************9 PP == domain 3 score: 18.2 bits; conditional E-value: 0.0002 TEEEEEEESSSS.EEEEE.EETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtsla.fspdgawlasGsdDgtvriW 37 ++c ++++GH++ v + +++d++ +as+s D+t+++W tr|B4DZI8|B4DZI8_HUMAN 103 WSCSQVFEGHTHyVMQIViNPKDNNQFASASLDRTIKVW 141 6899******66797777688888889************ PP == domain 4 score: 27.7 bits; conditional E-value: 2.1e-07 EEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 + tl+GH ++v++++ d+++l+sG dD+ v+iWd tr|B4DZI8|B4DZI8_HUMAN 148 PNFTLEGHeKGVNCIDyySGGDKPYLISGADDRLVKIWD 186 56799***********888888888*************9 PP == domain 5 score: 35.5 bits; conditional E-value: 7.1e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +c++tl+GH ++v++ +f+p+ + +++Gs+DgtvriW tr|B4DZI8|B4DZI8_HUMAN 191 TCVQTLEGHaQNVSCASFHPELPIIITGSEDGTVRIW 227 69*******988************************* PP >> sp|O43815-2|STRN_HUMAN Isoform 2 of Striatin OS=Homo sapiens GN=STRN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.0 1.2e-06 9.4e-05 1 38 [] 404 442 .. 404 442 .. 0.93 2 ! 14.8 0.0 0.0025 0.2 2 38 .] 458 495 .. 457 495 .. 0.91 3 ! 24.0 0.1 2.9e-06 0.00024 7 38 .] 516 548 .. 510 548 .. 0.89 4 ? 6.3 0.0 1.1 93 12 38 .] 615 643 .. 599 643 .. 0.81 5 ! 33.3 0.0 3.5e-09 2.8e-07 1 38 [] 647 685 .. 647 685 .. 0.96 6 ! 17.5 0.0 0.00034 0.028 2 32 .. 690 725 .. 689 730 .. 0.85 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.2e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ tl+ H +++++laf+p + l+++s+D+t+++W+ sp|O43815-2|STRN_HUMAN 404 WNPKFTLRSHfDGIRALAFHPIEPVLITASEDHTLKMWN 442 578899****777*************************8 PP == domain 2 score: 14.8 bits; conditional E-value: 0.0025 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++t+++H ++v ++ s++g sG+ Dg + W+ sp|O43815-2|STRN_HUMAN 458 EPIYTFRAHkGPVLCVVMSSNGEQCYSGGTDGLIQGWN 495 5899*****777****************99**998886 PP == domain 3 score: 24.0 bits; conditional E-value: 2.9e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH + v++la+s ++ l+s+s Dgt+r+W+ sp|O43815-2|STRN_HUMAN 516 LLGHtDAVWGLAYSAAHQRLLSCSADGTLRLWN 548 569*666*************************8 PP == domain 4 score: 6.3 bits; conditional E-value: 1.1 S..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s..vtslafspdgawlasGsdDgtvriWd 38 s ++ + +p + +++++D++++++d sp|O43815-2|STRN_HUMAN 615 ScqINRVISHPTLPISITAHEDRHIKFYD 643 246999999999999899*********98 PP == domain 5 score: 33.3 bits; conditional E-value: 3.5e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+++++ +H vtsla++p+g +l+sGs D+++r+W+ sp|O43815-2|STRN_HUMAN 647 GKLIHSMVAHlEAVTSLAVDPNGLYLMSGSHDCSIRLWN 685 68899*****999****************99*******8 PP == domain 6 score: 17.5 bits; conditional E-value: 0.00034 EEEEEEESS..SS...EEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGH..ss...vtslafspdgawlasGsdDg 32 +c++++t+H ++ ++++af+p++ ++as++ D sp|O43815-2|STRN_HUMAN 690 TCIQEFTAHrkKFeesIHDVAFHPSKCYIASAGADA 725 699******9544999**************998886 PP >> sp|O14775|GBB5_HUMAN Guanine nucleotide-binding protein subunit beta-5 OS=Homo sapiens GN=GNB5 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 0.2 7e-08 5.7e-06 3 38 .] 97 133 .. 95 133 .. 0.93 2 ? 5.3 0.0 2.4 1.9e+02 12 37 .. 149 174 .. 135 174 .. 0.81 3 ? 8.9 0.1 0.18 15 13 38 .] 198 223 .. 188 223 .. 0.64 4 ! 23.7 0.1 3.8e-06 0.0003 1 38 [] 227 267 .. 227 267 .. 0.91 5 ! 28.9 0.0 8.4e-08 6.8e-06 1 38 [] 271 309 .. 271 309 .. 0.97 6 ! 13.0 0.1 0.0088 0.71 14 38 .] 329 353 .. 320 353 .. 0.91 7 ! 27.2 0.7 2.9e-07 2.4e-05 4 37 .. 360 394 .. 357 394 .. 0.91 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 7e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + rtl+GH + v ++++++d++ ++s+s Dg+v +Wd sp|O14775|GBB5_HUMAN 97 TRRTLKGHgNKVLCMDWCKDKRRIVSSSQDGKVIVWD 133 6799****888*************************9 PP == domain 2 score: 5.3 bits; conditional E-value: 2.4 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +v ++a+ p+g +a+G+ D+++ ++ sp|O14775|GBB5_HUMAN 149 WVMACAYAPSGCAIACGGLDNKCSVY 174 488999************9*999875 PP == domain 3 score: 8.9 bits; conditional E-value: 0.18 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++f + ++++s Dgt+ +Wd sp|O14775|GBB5_HUMAN 198 LSACSFTNSDMQILTASGDGTCALWD 223 555554444444555544*******9 PP == domain 4 score: 23.7 bits; conditional E-value: 3.8e-06 TEEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 gq+l+++ GH +v +l+ s g+ ++sG+ D++ ++Wd sp|O14775|GBB5_HUMAN 227 GQLLQSFHGHgADVLCLDlaPSETGNTFVSGGCDKKAMVWD 267 689*******888988888899999999***88*******9 PP == domain 5 score: 28.9 bits; conditional E-value: 8.4e-08 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqc++ +++H s+++s+++ p+g+ +asGsdD t+r++d sp|O14775|GBB5_HUMAN 271 GQCVQAFETHeSDINSVRYYPSGDAFASGSDDATCRLYD 309 79********999************************98 PP == domain 6 score: 13.0 bits; conditional E-value: 0.0088 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 +s++fs +g++l++G D t+ +Wd sp|O14775|GBB5_HUMAN 329 SSVDFSLSGRLLFAGYNDYTINVWD 353 5899999********99*******9 PP == domain 7 score: 27.2 bits; conditional E-value: 2.9e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l GH + v+ l++spdg+ ++sGs+D+t+r+W sp|O14775|GBB5_HUMAN 360 VSILFGHeNRVSTLRVSPDGTAFCSGSWDHTLRVW 394 56777**999************************* PP >> sp|O43815|STRN_HUMAN Striatin OS=Homo sapiens GN=STRN PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.0 1.3e-06 0.0001 1 38 [] 453 491 .. 453 491 .. 0.93 2 ! 14.7 0.0 0.0027 0.22 2 38 .] 507 544 .. 506 544 .. 0.91 3 ! 23.9 0.1 3.2e-06 0.00026 7 38 .] 565 597 .. 559 597 .. 0.89 4 ? 6.2 0.0 1.2 1e+02 12 38 .] 664 692 .. 648 692 .. 0.81 5 ! 33.2 0.0 3.8e-09 3.1e-07 1 38 [] 696 734 .. 696 734 .. 0.96 6 ! 17.4 0.0 0.00037 0.03 2 32 .. 739 774 .. 738 779 .. 0.85 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 1.3e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ tl+ H +++++laf+p + l+++s+D+t+++W+ sp|O43815|STRN_HUMAN 453 WNPKFTLRSHfDGIRALAFHPIEPVLITASEDHTLKMWN 491 578899****777*************************8 PP == domain 2 score: 14.7 bits; conditional E-value: 0.0027 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++t+++H ++v ++ s++g sG+ Dg + W+ sp|O43815|STRN_HUMAN 507 EPIYTFRAHkGPVLCVVMSSNGEQCYSGGTDGLIQGWN 544 5899*****777****************99**998886 PP == domain 3 score: 23.9 bits; conditional E-value: 3.2e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH + v++la+s ++ l+s+s Dgt+r+W+ sp|O43815|STRN_HUMAN 565 LLGHtDAVWGLAYSAAHQRLLSCSADGTLRLWN 597 569*666*************************8 PP == domain 4 score: 6.2 bits; conditional E-value: 1.2 S..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s..vtslafspdgawlasGsdDgtvriWd 38 s ++ + +p + +++++D++++++d sp|O43815|STRN_HUMAN 664 ScqINRVISHPTLPISITAHEDRHIKFYD 692 246999999999999899*********98 PP == domain 5 score: 33.2 bits; conditional E-value: 3.8e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+++++ +H vtsla++p+g +l+sGs D+++r+W+ sp|O43815|STRN_HUMAN 696 GKLIHSMVAHlEAVTSLAVDPNGLYLMSGSHDCSIRLWN 734 68899*****999****************99*******8 PP == domain 6 score: 17.4 bits; conditional E-value: 0.00037 EEEEEEESS..SS...EEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGH..ss...vtslafspdgawlasGsdDg 32 +c++++t+H ++ ++++af+p++ ++as++ D sp|O43815|STRN_HUMAN 739 TCIQEFTAHrkKFeesIHDVAFHPSKCYIASAGADA 774 699******9544999**************998886 PP >> sp|Q9Y263|PLAP_HUMAN Phospholipase A-2-activating protein OS=Homo sapiens GN=PLAA PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 0.072 5.8 5 37 .. 12 46 .. 8 46 .. 0.75 2 ! 18.0 0.6 0.00023 0.019 3 37 .. 57 97 .. 55 98 .. 0.89 3 ! 22.2 0.2 1.2e-05 0.00093 3 37 .. 104 138 .. 103 138 .. 0.93 4 ! 27.1 0.0 3.2e-07 2.6e-05 2 38 .] 142 179 .. 141 179 .. 0.94 5 ! 15.4 0.0 0.0015 0.12 1 37 [. 181 217 .. 181 218 .. 0.89 6 ! 20.8 0.0 3.1e-05 0.0025 1 38 [] 221 259 .. 221 259 .. 0.81 7 ! 13.5 0.1 0.0061 0.5 9 37 .. 271 297 .. 261 298 .. 0.77 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.072 EEEESS.SS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ss....vtslafspdgawlasGsdDgtvriW 37 +l+GH + v++ p ga++ s s+D+t r+W sp|Q9Y263|PLAP_HUMAN 12 CSLRGHeLDvrglVCCA--YPPGAFV-SVSRDRTTRLW 46 5799**75545556555..8888997.5788******* PP == domain 2 score: 18.0 bits; conditional E-value: 0.00023 EEEEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 ++ +GH ++v++++ p+++ +a+G+ D+++ i+ sp|Q9Y263|PLAP_HUMAN 57 EMHCMSGHsNFVSCVCIIPSSDIyphglIATGGNDHNICIF 97 578899**888*****99999999999889********997 PP == domain 3 score: 22.2 bits; conditional E-value: 1.2e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l++l+GH + v+sl+ + g++l sGs+D t ++W sp|Q9Y263|PLAP_HUMAN 104 PLYILKGHkNTVCSLSSGKFGTLL-SGSWDTTAKVW 138 6899****888****999999998.7********** PP == domain 4 score: 27.1 bits; conditional E-value: 3.2e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ tl GH v++++ p++ ++++Gs D+tv++W+ sp|Q9Y263|PLAP_HUMAN 142 KCMMTLQGHtAAVWAVKILPEQGLMLTGSADKTVKLWK 179 79*******777*************************6 PP == domain 5 score: 15.4 bits; conditional E-value: 0.0015 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+c rt++GH ++v++la ++ +l+ + D ++r W sp|Q9Y263|PLAP_HUMAN 181 GRCERTFSGHeDCVRGLAILSETEFLS-CANDASIRRW 217 689*******888************96.666****988 PP == domain 6 score: 20.8 bits; conditional E-value: 3.1e-05 TEEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 g+cl ++ GH + ++s++ f+ +++ + +D+++riW+ sp|Q9Y263|PLAP_HUMAN 221 GECLEVYYGHtNYIYSISvFPNCRDFV-TTAEDRSLRIWK 259 68********888*****666666665.5566*******6 PP == domain 7 score: 13.5 bits; conditional E-value: 0.0061 SSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriW 37 ++ s++++++ ++g+ ++ +s Dg +r++ sp|Q9Y263|PLAP_HUMAN 271 AQ-SIWCCCVLDNGDIVVGAS-DGIIRVF 297 55.8************99447.*****96 PP >> sp|Q96KV7|WDR90_HUMAN WD repeat-containing protein 90 OS=Homo sapiens GN=WDR90 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 6.8 5.5e+02 4 28 .. 402 427 .. 400 439 .. 0.75 2 ? 6.9 0.3 0.76 61 12 33 .. 454 476 .. 443 478 .. 0.76 3 ? 7.1 0.0 0.66 53 9 37 .. 501 531 .. 494 532 .. 0.70 4 ? 4.7 0.0 3.8 3.1e+02 13 37 .. 622 644 .. 607 644 .. 0.75 5 ? 5.9 0.1 1.6 1.3e+02 10 33 .. 657 681 .. 650 692 .. 0.83 6 ? 10.8 0.0 0.046 3.7 9 38 .] 698 728 .. 687 728 .. 0.73 7 ? 7.0 0.0 0.73 59 7 34 .. 780 808 .. 775 812 .. 0.77 8 ? 3.5 0.0 9.2 7.4e+02 15 38 .] 933 955 .. 918 955 .. 0.85 9 ! 13.3 0.0 0.0073 0.59 6 31 .. 966 991 .. 964 997 .. 0.84 10 ? 10.5 0.6 0.055 4.5 4 38 .] 1151 1192 .. 1149 1192 .. 0.80 11 ? 8.4 0.1 0.25 20 9 35 .. 1204 1233 .. 1196 1235 .. 0.70 12 ! 22.6 0.2 8.5e-06 0.00069 5 37 .. 1429 1462 .. 1425 1462 .. 0.91 13 ? 4.9 0.0 3.4 2.7e+02 18 37 .. 1491 1510 .. 1475 1511 .. 0.71 14 ? 10.2 0.0 0.068 5.5 10 34 .. 1522 1549 .. 1515 1551 .. 0.80 15 ? 6.3 0.2 1.2 98 3 37 .. 1559 1604 .. 1557 1604 .. 0.77 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.8 EEEEESS.SSEEEEEEETTSSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG 28 +r + GH + v++la + ++++las+ sp|Q96KV7|WDR90_HUMAN 402 QRFFLGHtDKVSALALDGSSSLLASA 427 57788**555*************986 PP == domain 2 score: 6.9 bits; conditional E-value: 0.76 S.EEEEEEETTSSEEEEE.ETTSE CS WD40 12 s.vtslafspdgawlasG.sdDgt 33 + v+sl+fs++ga+l +G ++D++ sp|Q96KV7|WDR90_HUMAN 454 HvVCSLSFSDSGALL-CGvGKDHH 476 237***********9.58899997 PP == domain 3 score: 7.1 bits; conditional E-value: 0.66 SS..SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 9 GH..ssvtsla.fspdgawlasGsdDgtvriW 37 +H ++v +++ + d + +as++ g+vr+W sp|Q96KV7|WDR90_HUMAN 501 AHtdFDVQAFRvTFFDETRMASCG-QGSVRLW 531 6753337666664445566699**.******* PP == domain 4 score: 4.7 bits; conditional E-value: 3.8 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++sl s + a+ a Gs+Dg +r+W sp|Q96KV7|WDR90_HUMAN 622 ISSL--SVSPAMCAVGSEDGFLRLW 644 5666..566677788********** PP == domain 5 score: 5.9 bits; conditional E-value: 1.6 S.SSEEEEEEETTSSEEEEEETTSE CS WD40 10 H.ssvtslafspdgawlasGsdDgt 33 H ++v+s+++spdg ++s++ g+ sp|Q96KV7|WDR90_HUMAN 657 HeGPVSSVCVSPDGLRVLSATSSGH 681 8888************987743554 PP == domain 6 score: 10.8 bits; conditional E-value: 0.046 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +v +la + la+ s D+tvriWd sp|Q96KV7|WDR90_HUMAN 698 SHtAPVLALAMEQRRGQLATVSQDRTVRIWD 728 676667777544444448999*********9 PP == domain 7 score: 7.0 bits; conditional E-value: 0.73 EESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtv 34 t H + vt+l pdg++l+s++ g++ sp|Q96KV7|WDR90_HUMAN 780 HTCHrGAVTGLTATPDGRLLFSSCSQGSL 808 3578777************9865438775 PP == domain 8 score: 3.5 bits; conditional E-value: 9.2 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 sl s d ++l+ + +t+++Wd sp|Q96KV7|WDR90_HUMAN 933 SLTLSEDARFLLIAA-GRTIKVWD 955 566788999999999.*******9 PP == domain 9 score: 13.3 bits; conditional E-value: 0.0073 EEESS.SSEEEEEEETTSSEEEEEETT CS WD40 6 tltGH.ssvtslafspdgawlasGsdD 31 ++ GH +v ++afspd++ ++s++ D sp|Q96KV7|WDR90_HUMAN 966 VYIGHsEPVQAVAFSPDQQQVLSAG-D 991 789**777*************9887.5 PP == domain 10 score: 10.5 bits; conditional E-value: 0.055 EEEEESS.SSEEEEEEETTSSEEEEEE.T.....TSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGs.d.....DgtvriWd 38 +++++GH ++ la s++ + las+s + + +r+Wd sp|Q96KV7|WDR90_HUMAN 1151 QQHWSGHsAEISTLALSHSAQVLASASgRssttaHCQIRVWD 1192 6899***555*************97643244556*******9 PP == domain 11 score: 8.4 bits; conditional E-value: 0.25 SS.SSEEEEEEETTSSEEEE.E.ETTSEEE CS WD40 9 GH.ssvtslafspdgawlas.G.sdDgtvr 35 H + v +lafspd ++l++ G +d +t+ sp|Q96KV7|WDR90_HUMAN 1204 PHsTTVLALAFSPDDRLLVTlGdHDGRTLA 1233 58555*************986744555555 PP == domain 12 score: 22.6 bits; conditional E-value: 8.5e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 r ++GH s v+ + fsp + a++s+Dg+vr+W sp|Q96KV7|WDR90_HUMAN 1429 RLISGHrSKVNEVVFSPGESHCATCSEDGSVRVW 1462 5578**988************************* PP == domain 13 score: 4.9 bits; conditional E-value: 3.4 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 p+++ la+G Dg++ri+ sp|Q96KV7|WDR90_HUMAN 1491 GRPEQQRLAAGYGDGSLRIF 1510 5677777****55******7 PP == domain 14 score: 10.2 bits; conditional E-value: 0.068 S.SSE..EEEEEETTSSEEEEEETTSEE CS WD40 10 H.ssv..tslafspdgawlasGsdDgtv 34 H +v t +afs dg+ ++sG++Dg v sp|Q96KV7|WDR90_HUMAN 1522 HpHPValTTVAFSTDGQTVLSGDKDGLV 1549 5335444******************976 PP == domain 15 score: 6.3 bits; conditional E-value: 1.2 EEEEEESS..SSEEEEE..........EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH..ssvtsla..........fspdgawlasGsdDgtvriW 37 + r+l+ H +++ ++ + wla+++ D+ v +W sp|Q96KV7|WDR90_HUMAN 1559 TFRVLSDHqgAPISTICvtckecedlgVEGTDLWLAASG-DQRVSVW 1604 567888886444766666688888888888889***999.******* PP >> tr|F8VUX9|F8VUX9_HUMAN WD repeat-containing protein 90 OS=Homo sapiens GN=WDR90 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 6.9 5.6e+02 4 28 .. 402 427 .. 400 439 .. 0.75 2 ? 6.9 0.3 0.76 61 12 33 .. 454 476 .. 443 478 .. 0.76 3 ? 7.1 0.0 0.66 53 9 37 .. 501 531 .. 494 532 .. 0.70 4 ? 4.7 0.0 3.8 3.1e+02 13 37 .. 622 644 .. 607 644 .. 0.75 5 ? 5.9 0.1 1.6 1.3e+02 10 33 .. 657 681 .. 650 692 .. 0.83 6 ? 10.8 0.0 0.046 3.7 9 38 .] 698 728 .. 687 728 .. 0.73 7 ? 7.0 0.0 0.73 59 7 34 .. 780 808 .. 775 812 .. 0.77 8 ? 3.5 0.0 9.2 7.4e+02 15 38 .] 933 955 .. 918 955 .. 0.85 9 ! 13.3 0.0 0.0073 0.59 6 31 .. 966 991 .. 964 997 .. 0.84 10 ? 10.5 0.6 0.056 4.5 4 38 .] 1151 1192 .. 1149 1192 .. 0.80 11 ? 8.4 0.1 0.25 20 9 35 .. 1204 1233 .. 1196 1235 .. 0.70 12 ! 22.6 0.2 8.5e-06 0.00069 5 37 .. 1431 1464 .. 1427 1464 .. 0.91 13 ? 4.9 0.0 3.4 2.7e+02 18 37 .. 1493 1512 .. 1477 1513 .. 0.71 14 ? 10.2 0.0 0.068 5.5 10 34 .. 1524 1551 .. 1517 1553 .. 0.80 15 ? 6.3 0.2 1.2 98 3 37 .. 1561 1606 .. 1559 1606 .. 0.77 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.9 EEEEESS.SSEEEEEEETTSSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG 28 +r + GH + v++la + ++++las+ tr|F8VUX9|F8VUX9_HUMAN 402 QRFFLGHtDKVSALALDGSSSLLASA 427 57788**555*************986 PP == domain 2 score: 6.9 bits; conditional E-value: 0.76 S.EEEEEEETTSSEEEEE.ETTSE CS WD40 12 s.vtslafspdgawlasG.sdDgt 33 + v+sl+fs++ga+l +G ++D++ tr|F8VUX9|F8VUX9_HUMAN 454 HvVCSLSFSDSGALL-CGvGKDHH 476 237***********9.58899997 PP == domain 3 score: 7.1 bits; conditional E-value: 0.66 SS..SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 9 GH..ssvtsla.fspdgawlasGsdDgtvriW 37 +H ++v +++ + d + +as++ g+vr+W tr|F8VUX9|F8VUX9_HUMAN 501 AHtdFDVQAFRvTFFDETRMASCG-QGSVRLW 531 6753337666664445566699**.******* PP == domain 4 score: 4.7 bits; conditional E-value: 3.8 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++sl s + a+ a Gs+Dg +r+W tr|F8VUX9|F8VUX9_HUMAN 622 ISSL--SVSPAMCAVGSEDGFLRLW 644 5666..566677788********** PP == domain 5 score: 5.9 bits; conditional E-value: 1.6 S.SSEEEEEEETTSSEEEEEETTSE CS WD40 10 H.ssvtslafspdgawlasGsdDgt 33 H ++v+s+++spdg ++s++ g+ tr|F8VUX9|F8VUX9_HUMAN 657 HeGPVSSVCVSPDGLRVLSATSSGH 681 8888************987743554 PP == domain 6 score: 10.8 bits; conditional E-value: 0.046 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +v +la + la+ s D+tvriWd tr|F8VUX9|F8VUX9_HUMAN 698 SHtAPVLALAMEQRRGQLATVSQDRTVRIWD 728 676667777544444448999*********9 PP == domain 7 score: 7.0 bits; conditional E-value: 0.73 EESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtv 34 t H + vt+l pdg++l+s++ g++ tr|F8VUX9|F8VUX9_HUMAN 780 HTCHrGAVTGLTATPDGRLLFSSCSQGSL 808 3578777************9865438775 PP == domain 8 score: 3.5 bits; conditional E-value: 9.2 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 sl s d ++l+ + +t+++Wd tr|F8VUX9|F8VUX9_HUMAN 933 SLTLSEDARFLLIAA-GRTIKVWD 955 566788999999999.*******9 PP == domain 9 score: 13.3 bits; conditional E-value: 0.0073 EEESS.SSEEEEEEETTSSEEEEEETT CS WD40 6 tltGH.ssvtslafspdgawlasGsdD 31 ++ GH +v ++afspd++ ++s++ D tr|F8VUX9|F8VUX9_HUMAN 966 VYIGHsEPVQAVAFSPDQQQVLSAG-D 991 789**777*************9887.5 PP == domain 10 score: 10.5 bits; conditional E-value: 0.056 EEEEESS.SSEEEEEEETTSSEEEEEE.T.....TSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGs.d.....DgtvriWd 38 +++++GH ++ la s++ + las+s + + +r+Wd tr|F8VUX9|F8VUX9_HUMAN 1151 QQHWSGHsAEISTLALSHSAQVLASASgRssttaHCQIRVWD 1192 6899***555*************97643244556*******9 PP == domain 11 score: 8.4 bits; conditional E-value: 0.25 SS.SSEEEEEEETTSSEEEE.E.ETTSEEE CS WD40 9 GH.ssvtslafspdgawlas.G.sdDgtvr 35 H + v +lafspd ++l++ G +d +t+ tr|F8VUX9|F8VUX9_HUMAN 1204 PHsTTVLALAFSPDDRLLVTlGdHDGRTLA 1233 58555*************986744555555 PP == domain 12 score: 22.6 bits; conditional E-value: 8.5e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 r ++GH s v+ + fsp + a++s+Dg+vr+W tr|F8VUX9|F8VUX9_HUMAN 1431 RLISGHrSKVNEVVFSPGESHCATCSEDGSVRVW 1464 5578**988************************* PP == domain 13 score: 4.9 bits; conditional E-value: 3.4 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 p+++ la+G Dg++ri+ tr|F8VUX9|F8VUX9_HUMAN 1493 GRPEQQRLAAGYGDGSLRIF 1512 5677777****55******7 PP == domain 14 score: 10.2 bits; conditional E-value: 0.068 S.SSE..EEEEEETTSSEEEEEETTSEE CS WD40 10 H.ssv..tslafspdgawlasGsdDgtv 34 H +v t +afs dg+ ++sG++Dg v tr|F8VUX9|F8VUX9_HUMAN 1524 HpHPValTTVAFSTDGQTVLSGDKDGLV 1551 5335444******************976 PP == domain 15 score: 6.3 bits; conditional E-value: 1.2 EEEEEESS..SSEEEEE..........EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH..ssvtsla..........fspdgawlasGsdDgtvriW 37 + r+l+ H +++ ++ + wla+++ D+ v +W tr|F8VUX9|F8VUX9_HUMAN 1561 TFRVLSDHqgAPISTICvtckecedlgVEGTDLWLAASG-DQRVSVW 1606 567888886444766666688888888888889***999.******* PP >> tr|B3KPU1|B3KPU1_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Homo sapiens GN=GNB2 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.068 5.5 16 37 .. 3 24 .. 1 25 [. 0.90 2 ! 20.5 0.2 3.9e-05 0.0031 4 38 .] 36 70 .. 33 70 .. 0.90 3 ! 24.4 0.1 2.2e-06 0.00018 7 38 .] 80 112 .. 74 112 .. 0.87 4 ! 29.4 0.0 5.9e-08 4.8e-06 3 38 .] 118 154 .. 116 154 .. 0.96 5 ! 24.6 0.1 1.9e-06 0.00015 10 38 .] 166 198 .. 159 198 .. 0.84 6 ! 21.1 0.6 2.4e-05 0.002 5 38 .] 206 240 .] 202 240 .] 0.92 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.068 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +a+ p+g+++a+G+ D+ + i+ tr|B3KPU1|B3KPU1_HUMAN 3 CAYAPSGNFVACGGLDNICSIY 24 6799***************998 PP == domain 2 score: 20.5 bits; conditional E-value: 3.9e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + ++++f +d++ ++s++ D t+ +Wd tr|B3KPU1|B3KPU1_HUMAN 36 SRELPGHtGYLSCCRFLDDNQIITSSG-DTTCALWD 70 57899**666*************9999.*******9 PP == domain 3 score: 24.4 bits; conditional E-value: 2.2e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH ++v sl+ pdg+ ++sG D ++++Wd tr|B3KPU1|B3KPU1_HUMAN 80 FAGHsGDVMSLSLAPDGRTFVSGACDASIKLWD 112 78**777****************77*******9 PP == domain 4 score: 29.4 bits; conditional E-value: 5.9e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +t+ GH s+++++af p+g +++GsdD t+r++d tr|B3KPU1|B3KPU1_HUMAN 118 CRQTFIGHeSDINAVAFFPNGYAFTTGSDDATCRLFD 154 889*****999************************98 PP == domain 5 score: 24.6 bits; conditional E-value: 1.9e-06 S.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ss...vtslafspdgawlasGsdDgtvriWd 38 H + +ts+afs++g++l++G dD ++ iWd tr|B3KPU1|B3KPU1_HUMAN 166 HdNIicgITSVAFSRSGRLLLAGYDDFNCNIWD 198 74336669************************9 PP == domain 6 score: 21.1 bits; conditional E-value: 2.4e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l GH + v++l + +dg +a+Gs+D ++iW+ tr|B3KPU1|B3KPU1_HUMAN 206 GVLAGHdNRVSCLGVTDDGMAVATGSWDSFLKIWN 240 5788**888*************************8 PP >> sp|Q6RI45-5|BRWD3_HUMAN Isoform 5 of Bromodomain and WD repeat-containing protein 3 OS=Homo sapiens GN=BRWD3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.5 0.4 2.3e-07 1.9e-05 6 37 .. 176 207 .. 169 207 .. 0.92 2 ! 23.0 0.0 6.2e-06 0.00051 1 37 [. 212 249 .. 212 250 .. 0.92 3 ! 17.2 0.1 0.00042 0.034 3 37 .. 256 295 .. 254 296 .. 0.81 4 ? 9.9 0.0 0.088 7.1 13 37 .. 321 345 .. 311 345 .. 0.89 5 ! 19.3 0.0 9.1e-05 0.0074 4 37 .. 355 391 .. 352 392 .. 0.84 6 ! 20.0 0.1 5.5e-05 0.0045 1 38 [] 455 494 .. 455 494 .. 0.71 7 ? 11.7 0.2 0.023 1.9 7 32 .. 510 533 .. 503 540 .. 0.80 Alignments for each domain: == domain 1 score: 27.5 bits; conditional E-value: 2.3e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l GH ssv+++af+++g+ +++GsdD+ v+iW sp|Q6RI45-5|BRWD3_HUMAN 176 IL-GHlSSVYCVAFDRSGRRIFTGSDDCLVKIW 207 34.9***************************** PP == domain 2 score: 23.0 bits; conditional E-value: 6.2e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l tl+GH ++++a++ +++++a+Gs D+ vr+W sp|Q6RI45-5|BRWD3_HUMAN 212 GRLLATLRGHsAEISDMAVNYENTLIAAGSCDKVVRVW 249 57899*****555****************99******* PP == domain 3 score: 17.2 bits; conditional E-value: 0.00042 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriW 37 ++ +l GH s+ts++f+p+ + l+s + Dgt+ +W sp|Q6RI45-5|BRWD3_HUMAN 256 PVAVLQGHsASITSIQFCPSTKGtnryLTSTGADGTICFW 295 7889****777****977777667777986666******* PP == domain 4 score: 9.9 bits; conditional E-value: 0.088 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ +fs+ g ++++Gs D+ +ri+ sp|Q6RI45-5|BRWD3_HUMAN 321 ISCSSFSSGGMFITTGSTDHVIRIY 345 67778******************97 PP == domain 5 score: 19.3 bits; conditional E-value: 9.1e-05 EEEEESS.SSEEEEEEETTSSEE..EEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawl..asGsdDgtvriW 37 + +l+ H + v +++f+ +g+ l +sGs+Dgt riW sp|Q6RI45-5|BRWD3_HUMAN 355 IAELESHtDKVVAVQFCNNGDSLrfVSGSRDGTARIW 391 678999*55599***9******6559*********** PP == domain 6 score: 20.0 bits; conditional E-value: 5.5e-05 TEEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 gq+l+tl+GH + v l + d++ ++s++ Dg++ iWd sp|Q6RI45-5|BRWD3_HUMAN 455 GQLLHTLSGHdDEVFVLEaHPFDQRIILSAGHDGNIFIWD 494 799*******5557666633555555556555*******9 PP == domain 7 score: 11.7 bits; conditional E-value: 0.023 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fspdg+ +a ++ D sp|Q6RI45-5|BRWD3_HUMAN 510 GQGHGAVFDCKFSPDGNHFA-CT-DS 533 569988************97.66.54 PP >> sp|O14775-3|GBB5_HUMAN Isoform 3 of Guanine nucleotide-binding protein subunit beta-5 OS=Homo sapiens GN=GNB5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.8 0.2 4.4e-08 3.6e-06 3 38 .] 55 91 .. 53 91 .. 0.93 2 ? 7.2 0.1 0.61 49 23 38 .] 97 111 .. 92 111 .. 0.74 3 ! 24.4 0.1 2.3e-06 0.00019 1 38 [] 115 155 .. 115 155 .. 0.91 4 ! 29.6 0.0 5.2e-08 4.2e-06 1 38 [] 159 197 .. 159 197 .. 0.97 5 ! 13.7 0.1 0.0055 0.44 14 38 .] 217 241 .. 207 241 .. 0.91 6 ! 27.8 0.7 1.8e-07 1.5e-05 4 37 .. 248 282 .. 245 282 .. 0.91 Alignments for each domain: == domain 1 score: 29.8 bits; conditional E-value: 4.4e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + rtl+GH + v ++++++d++ ++s+s Dg+v +Wd sp|O14775-3|GBB5_HUMAN 55 TRRTLKGHgNKVLCMDWCKDKRRIVSSSQDGKVIVWD 91 6799****888*************************9 PP == domain 2 score: 7.2 bits; conditional E-value: 0.61 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 + l++++ Dgt+ +Wd sp|O14775-3|GBB5_HUMAN 97 KILTASG-DGTCALWD 111 3466667.*******9 PP == domain 3 score: 24.4 bits; conditional E-value: 2.3e-06 TEEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 gq+l+++ GH +v +l+ s g+ ++sG+ D++ ++Wd sp|O14775-3|GBB5_HUMAN 115 GQLLQSFHGHgADVLCLDlaPSETGNTFVSGGCDKKAMVWD 155 689*******888988888899999999***88*******9 PP == domain 4 score: 29.6 bits; conditional E-value: 5.2e-08 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqc++ +++H s+++s+++ p+g+ +asGsdD t+r++d sp|O14775-3|GBB5_HUMAN 159 GQCVQAFETHeSDINSVRYYPSGDAFASGSDDATCRLYD 197 79********999************************98 PP == domain 5 score: 13.7 bits; conditional E-value: 0.0055 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 +s++fs +g++l++G D t+ +Wd sp|O14775-3|GBB5_HUMAN 217 SSVDFSLSGRLLFAGYNDYTINVWD 241 5899999********99*******9 PP == domain 6 score: 27.8 bits; conditional E-value: 1.8e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l GH + v+ l++spdg+ ++sGs+D+t+r+W sp|O14775-3|GBB5_HUMAN 248 VSILFGHeNRVSTLRVSPDGTAFCSGSWDHTLRVW 282 56777**999************************* PP >> tr|D6R9L0|D6R9L0_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.8 0.6 5.6e-10 4.5e-08 3 38 .] 103 139 .. 101 139 .. 0.93 2 ! 36.2 0.2 4.1e-10 3.4e-08 3 38 .] 145 181 .. 143 181 .. 0.93 3 ! 24.4 1.0 2.2e-06 0.00018 9 38 .] 194 226 .. 184 226 .. 0.83 4 ! 24.0 0.2 2.9e-06 0.00024 7 38 .] 236 268 .. 230 268 .. 0.86 5 ? 10.8 0.0 0.046 3.7 2 28 .. 273 299 .. 272 300 .] 0.81 Alignments for each domain: == domain 1 score: 35.8 bits; conditional E-value: 5.6e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6R9L0|D6R9L0_HUMAN 103 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 139 7899****667************99***********9 PP == domain 2 score: 36.2 bits; conditional E-value: 4.1e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|D6R9L0|D6R9L0_HUMAN 145 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 181 678899******************************8 PP == domain 3 score: 24.4 bits; conditional E-value: 2.2e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|D6R9L0|D6R9L0_HUMAN 194 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 226 79666*************989***********8 PP == domain 4 score: 24.0 bits; conditional E-value: 2.9e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd tr|D6R9L0|D6R9L0_HUMAN 236 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 268 3499666*************************9 PP == domain 5 score: 10.8 bits; conditional E-value: 0.046 EEEEEEESSSS.EEEEEEETTSSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasG 28 ++l+tl+G + +++l+fsp+ wl+++ tr|D6R9L0|D6R9L0_HUMAN 273 KHLYTLDGG-DiINALCFSPNRYWLCAA 299 778888887.448***********9765 PP >> sp|O60508|PRP17_HUMAN Pre-mRNA-processing factor 17 OS=Homo sapiens GN=CDC40 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 0.2 2.3e-06 0.00019 2 37 .. 279 316 .. 278 317 .. 0.93 2 ! 27.8 0.0 1.9e-07 1.6e-05 2 38 .] 323 360 .. 322 360 .. 0.94 3 ? 12.0 0.0 0.019 1.5 2 38 .] 365 404 .. 364 404 .. 0.79 4 ! 14.6 0.0 0.0028 0.23 2 37 .. 409 445 .. 408 446 .. 0.85 5 ? 9.3 0.0 0.13 11 16 36 .. 467 487 .. 456 488 .. 0.84 6 ! 19.1 0.0 0.0001 0.0084 3 38 .] 498 536 .. 496 536 .. 0.86 7 ! 15.3 1.0 0.0017 0.14 7 38 .] 546 579 .] 540 579 .] 0.73 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 2.3e-06 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 +++++++GH ++v++++ f+ +g++l+s+s+D+++++W sp|O60508|PRP17_HUMAN 279 KQIHVWSGHtKGVSAVRlFPLSGHLLLSCSMDCKIKLW 316 6799*****999*****999999999************ PP == domain 2 score: 27.8 bits; conditional E-value: 1.9e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +clrt+ GH + v++++f+ g+ ++s+ +D+ +++Wd sp|O60508|PRP17_HUMAN 323 RCLRTFIGHsKAVRDICFNTAGTQFLSAAYDRYLKLWD 360 8********888************999999*******9 PP == domain 3 score: 12.0 bits; conditional E-value: 0.019 EEEEEEESSSSE.EEEEEETTSSE...EEEEETTSEEEEEE CS WD40 2 qclrtltGHssv.tslafspdgaw...lasGsdDgtvriWd 38 qc+ +t v ++++f+pd + +++G+ D+++ Wd sp|O60508|PRP17_HUMAN 365 QCISRFTNR-KVpYCVKFNPDEDKqnlFVAGMSDKKIVQWD 404 566666522.3779************8778*66*******9 PP == domain 4 score: 14.6 bits; conditional E-value: 0.0028 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +++++ H + v+ + f ++++ ++s sdD+++r+W sp|O60508|PRP17_HUMAN 409 EIVQEYDRHlGAVNTIVFVDENRRFVSTSDDKSLRVW 445 567889999999*99998888888888899******* PP == domain 5 score: 9.3 bits; conditional E-value: 0.13 EEEETTSSEEEEE.ETTSEEEE CS WD40 16 lafspdgawlasG.sdDgtvri 36 + sp+g+wla + s+D+ + i sp|O60508|PRP17_HUMAN 467 VTLSPNGKWLA-CqSMDNQILI 487 557******97.7699***988 PP == domain 6 score: 19.1 bits; conditional E-value: 0.0001 EEEEEESS..SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH..ss.vtslafspdgawlasGsdDgtvriWd 38 + ++++GH + + ++fspd ++++sG+ +g++ iWd sp|O60508|PRP17_HUMAN 498 KKKIFKGHmvAGyACQVDFSPDMSYVISGDGNGKLNIWD 536 56899***9744589999***********66*******9 PP == domain 7 score: 15.3 bits; conditional E-value: 0.0017 EESSSS..EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 7 ltGHss..vtslafspdgaw.lasGsdDgtvriWd 38 +++H+ + ++ ++p+ + ++++++Dg +++Wd sp|O60508|PRP17_HUMAN 546 FKAHDKvcIGAV-WHPHETSkVITCGWDGLIKLWD 579 899944235455.7777777678***********9 PP >> sp|Q9NSI6-3|BRWD1_HUMAN Isoform C of Bromodomain and WD repeat-containing protein 1 OS=Homo sapiens GN=BRWD1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.5 1.2e-06 9.7e-05 7 38 .] 183 214 .. 175 214 .. 0.91 2 ! 22.1 0.0 1.2e-05 0.00097 1 37 [. 218 255 .. 218 256 .. 0.92 3 ! 17.6 0.0 0.00032 0.026 3 37 .. 262 301 .. 260 302 .. 0.86 4 ? 6.3 0.0 1.2 94 17 37 .. 331 351 .. 319 351 .. 0.87 5 ! 20.5 0.0 3.7e-05 0.003 4 37 .. 361 395 .. 358 396 .. 0.89 6 ? 7.0 0.0 0.71 58 13 38 .] 429 454 .. 418 454 .. 0.90 7 ! 14.4 0.1 0.0032 0.26 1 38 [] 458 497 .. 458 497 .. 0.75 8 ? 8.3 0.2 0.28 23 7 32 .. 513 536 .. 502 543 .. 0.78 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.2e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH s v+++af++ g+ +++GsdD+ v+iW+ sp|Q9NSI6-3|BRWD1_HUMAN 183 L-GHlSAVYCVAFDRTGHRIFTGSDDCLVKIWS 214 3.9*999*************************5 PP == domain 2 score: 22.1 bits; conditional E-value: 1.2e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l tl+GH ++++a++ +++++a+Gs D+ +r+W sp|Q9NSI6-3|BRWD1_HUMAN 218 GRLLSTLRGHsAEISDMAVNYENTMIAAGSCDKIIRVW 255 57899*****555****************99******* PP == domain 3 score: 17.6 bits; conditional E-value: 0.00032 EEEEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 ++ +l GH +s+tsl+fsp + +++G Dgtv +W sp|Q9NSI6-3|BRWD1_HUMAN 262 PVAVLQGHtGSITSLQFSPMAKGsqrymVSTGA-DGTVCFW 301 7889****888****988888889999666777.******* PP == domain 4 score: 6.3 bits; conditional E-value: 1.2 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 +fs g +la+Gs D+ +r++ sp|Q9NSI6-3|BRWD1_HUMAN 331 SFSVGGMFLATGSTDHVIRMY 351 5999999************86 PP == domain 5 score: 20.5 bits; conditional E-value: 3.7e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+ H + v s++f+ +g+ ++sGs+Dgt riW sp|Q9NSI6-3|BRWD1_HUMAN 361 IAELESHtDKVDSIQFCNNGDRFLSGSRDGTARIW 395 678999*555************************* PP == domain 6 score: 7.0 bits; conditional E-value: 0.71 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 vt +a++++ + ++++ D+ +++W+ sp|Q9NSI6-3|BRWD1_HUMAN 429 VTMIAWNQNDSIVVTAVNDHVLKVWN 454 77799**********988*******8 PP == domain 7 score: 14.4 bits; conditional E-value: 0.0032 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 gq+l+ l GH + v l ++p + l++G+ Dg++ iWd sp|Q9NSI6-3|BRWD1_HUMAN 458 GQLLHNLMGHaDEVFVLETHPFDSRimLSAGH-DGSIFIWD 497 689999****6669888866666663234566.*******9 PP == domain 8 score: 8.3 bits; conditional E-value: 0.28 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fs+dg+ +a ++ D sp|Q9NSI6-3|BRWD1_HUMAN 513 GQGHGAVFDCKFSQDGQHFA-CT-DS 536 469988************97.65.43 PP >> sp|Q9Y6I7|WSB1_HUMAN WD repeat and SOCS box-containing protein 1 OS=Homo sapiens GN=WSB1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.1 0.095 7.7 17 38 .] 128 156 .. 96 156 .. 0.71 2 ! 26.0 0.0 7e-07 5.7e-05 2 38 .] 161 199 .. 160 199 .. 0.83 3 ! 25.2 0.1 1.2e-06 0.0001 2 38 .] 205 242 .. 204 242 .. 0.91 4 ! 33.0 0.1 4.3e-09 3.5e-07 4 38 .] 249 284 .. 246 284 .. 0.92 5 ! 15.6 0.0 0.0013 0.11 11 37 .. 310 338 .. 292 339 .. 0.82 6 ! 17.4 0.2 0.00036 0.029 15 37 .. 356 378 .. 350 378 .. 0.94 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.095 E.......EETTSSEEEEEETTSEEEEEE CS WD40 17 a.......fspdgawlasGsdDgtvriWd 38 f +d+ +la+G +g ++iWd sp|Q9Y6I7|WSB1_HUMAN 128 NiewhrfrFGQDQLLLATGLNNGRIKIWD 156 155555558899999****77*******9 PP == domain 2 score: 26.0 bits; conditional E-value: 7e-07 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 ++l l H+ v++l f pdg+++ +s+s+D+t+r+Wd sp|Q9Y6I7|WSB1_HUMAN 161 KLLLNLVDHTEvVRDLTFAPDGSLIlVSASRDKTLRVWD 199 5677788896657***********62589*********9 PP == domain 3 score: 25.2 bits; conditional E-value: 1.2e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++l+GH ++v+s+afspd+++l+s + + v +W+ sp|Q9Y6I7|WSB1_HUMAN 205 NMMKVLRGHqNWVYSCAFSPDSSMLCSVGASKAVFLWN 242 66899****999*************98777*******8 PP == domain 4 score: 33.0 bits; conditional E-value: 4.3e-09 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r+l+GH +v +++fspdga+la++s+D v+iWd sp|Q9Y6I7|WSB1_HUMAN 249 IRKLEGHhHDVVACDFSPDGALLATASYDTRVYIWD 284 6899***77799***********************9 PP == domain 5 score: 15.6 bits; conditional E-value: 0.0013 SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ss..vtslafspdgawlasGsdDgtvriW 37 ++ v+s++fs+dg +as dD+ vr+W sp|Q9Y6I7|WSB1_HUMAN 310 NDrwVRSVSFSHDGLHVASLADDKMVRFW 338 4467************985488******* PP == domain 6 score: 17.4 bits; conditional E-value: 0.00036 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++afs dg+ la+G+ Dg+v++W sp|Q9Y6I7|WSB1_HUMAN 356 CCAFSTDGSVLAAGTHDGSVYFW 378 999***********88******* PP >> sp|Q9BVC4-5|LST8_HUMAN Isoform 4 of Target of rapamycin complex subunit LST8 OS=Homo sapiens GN=MLST8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.084 6.8 24 37 .. 14 27 .. 8 28 .. 0.82 2 ! 14.4 0.0 0.0032 0.26 3 38 .] 34 68 .. 32 68 .. 0.89 3 ! 23.3 0.1 4.9e-06 0.00039 6 38 .] 79 112 .. 74 112 .. 0.82 4 ! 20.8 0.0 3.2e-05 0.0026 2 38 .] 119 155 .. 118 155 .. 0.96 5 ? 5.1 0.0 2.8 2.2e+02 12 38 .] 171 197 .. 158 197 .. 0.83 6 ! 23.7 0.0 3.9e-06 0.00031 15 37 .. 224 246 .. 208 247 .. 0.84 7 ! 13.9 0.3 0.0048 0.39 13 37 .. 272 296 .. 255 297 .. 0.85 8 ? 6.7 0.0 0.91 73 3 20 .. 303 321 .. 301 322 .. 0.83 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.084 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W sp|Q9BVC4-5|LST8_HUMAN 14 ILATAGYDHTVRFW 27 5788888******* PP == domain 2 score: 14.4 bits; conditional E-value: 0.0032 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c+rt H +sv++l + pd +++a+++ +++r++d sp|Q9BVC4-5|LST8_HUMAN 34 CTRTV-QHqDSVNALEVTPDRSMIAAAG-YQHIRMYD 68 78887.58788**************99*.******98 PP == domain 3 score: 23.3 bits; conditional E-value: 4.9e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd sp|Q9BVC4-5|LST8_HUMAN 79 SYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 112 5555445688999********************9 PP == domain 4 score: 20.8 bits; conditional E-value: 3.2e-05 EEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtslafspdgawlasGsdDgtvriWd 38 qc+r++ ++++++ +p++a l+ G+ g ++iWd sp|Q9BVC4-5|LST8_HUMAN 119 QCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWD 155 8******9999*************************9 PP == domain 5 score: 5.1 bits; conditional E-value: 2.8 SEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 12 svtslafspdgawlasG.sdDgtvriWd 38 s+ts +pd +++a+ s g++++W+ sp|Q9BVC4-5|LST8_HUMAN 171 SITSAHIDPDASYMAAVnS-TGNCYVWN 197 389999*******997767.*******8 PP == domain 6 score: 23.7 bits; conditional E-value: 3.9e-06 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++fspd+++la++s D+t++iW sp|Q9BVC4-5|LST8_HUMAN 224 QCRFSPDSTLLATCSADQTCKIW 246 466******************** PP == domain 7 score: 13.9 bits; conditional E-value: 0.0048 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++afs d+++++++s D+ r+W sp|Q9BVC4-5|LST8_HUMAN 272 MWGCAFSGDSQYIVTASSDNLARLW 296 5899**********9988******* PP == domain 8 score: 6.7 bits; conditional E-value: 0.91 EEEEEESS.SSEEEEEEET CS WD40 3 clrtltGH.ssvtslafsp 20 r++ GH + v +laf++ sp|Q9BVC4-5|LST8_HUMAN 303 IKREYGGHqKAVVCLAFND 321 6789****99999**9976 PP >> sp|Q9NSI6-2|BRWD1_HUMAN Isoform B of Bromodomain and WD repeat-containing protein 1 OS=Homo sapiens GN=BRWD1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.5 1.2e-06 0.0001 7 38 .] 183 214 .. 175 214 .. 0.91 2 ! 22.1 0.0 1.2e-05 0.001 1 37 [. 218 255 .. 218 256 .. 0.92 3 ! 17.5 0.0 0.00034 0.027 3 37 .. 262 301 .. 260 302 .. 0.86 4 ? 6.3 0.0 1.2 97 17 37 .. 331 351 .. 319 351 .. 0.87 5 ! 20.5 0.0 3.9e-05 0.0031 4 37 .. 361 395 .. 358 396 .. 0.89 6 ? 6.9 0.0 0.74 60 13 38 .] 429 454 .. 418 454 .. 0.90 7 ! 14.4 0.1 0.0033 0.27 1 38 [] 458 497 .. 458 497 .. 0.75 8 ? 8.2 0.2 0.29 24 7 32 .. 513 536 .. 502 543 .. 0.78 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 1.2e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH s v+++af++ g+ +++GsdD+ v+iW+ sp|Q9NSI6-2|BRWD1_HUMAN 183 L-GHlSAVYCVAFDRTGHRIFTGSDDCLVKIWS 214 3.9*999*************************5 PP == domain 2 score: 22.1 bits; conditional E-value: 1.2e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l tl+GH ++++a++ +++++a+Gs D+ +r+W sp|Q9NSI6-2|BRWD1_HUMAN 218 GRLLSTLRGHsAEISDMAVNYENTMIAAGSCDKIIRVW 255 57899*****555****************99******* PP == domain 3 score: 17.5 bits; conditional E-value: 0.00034 EEEEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 ++ +l GH +s+tsl+fsp + +++G Dgtv +W sp|Q9NSI6-2|BRWD1_HUMAN 262 PVAVLQGHtGSITSLQFSPMAKGsqrymVSTGA-DGTVCFW 301 7889****888****988888889999666777.******* PP == domain 4 score: 6.3 bits; conditional E-value: 1.2 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 +fs g +la+Gs D+ +r++ sp|Q9NSI6-2|BRWD1_HUMAN 331 SFSVGGMFLATGSTDHVIRMY 351 5999999************86 PP == domain 5 score: 20.5 bits; conditional E-value: 3.9e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+ H + v s++f+ +g+ ++sGs+Dgt riW sp|Q9NSI6-2|BRWD1_HUMAN 361 IAELESHtDKVDSIQFCNNGDRFLSGSRDGTARIW 395 678999*555************************* PP == domain 6 score: 6.9 bits; conditional E-value: 0.74 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 vt +a++++ + ++++ D+ +++W+ sp|Q9NSI6-2|BRWD1_HUMAN 429 VTMIAWNQNDSIVVTAVNDHVLKVWN 454 77799**********988*******8 PP == domain 7 score: 14.4 bits; conditional E-value: 0.0033 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 gq+l+ l GH + v l ++p + l++G+ Dg++ iWd sp|Q9NSI6-2|BRWD1_HUMAN 458 GQLLHNLMGHaDEVFVLETHPFDSRimLSAGH-DGSIFIWD 497 689999****6669888866666663234566.*******9 PP == domain 8 score: 8.2 bits; conditional E-value: 0.29 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fs+dg+ +a ++ D sp|Q9NSI6-2|BRWD1_HUMAN 513 GQGHGAVFDCKFSQDGQHFA-CT-DS 536 469988************97.65.43 PP >> sp|Q9BVC4|LST8_HUMAN Target of rapamycin complex subunit LST8 OS=Homo sapiens GN=MLST8 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.084 6.8 24 37 .. 14 27 .. 8 28 .. 0.82 2 ! 13.7 0.0 0.0053 0.43 3 38 .] 34 69 .. 32 69 .. 0.86 3 ! 23.3 0.1 4.9e-06 0.0004 6 38 .] 80 113 .. 75 113 .. 0.82 4 ! 20.8 0.0 3.2e-05 0.0026 2 38 .] 120 156 .. 119 156 .. 0.96 5 ? 5.1 0.0 2.8 2.3e+02 12 38 .] 172 198 .. 159 198 .. 0.83 6 ! 23.7 0.0 3.9e-06 0.00031 15 37 .. 225 247 .. 209 248 .. 0.84 7 ! 13.8 0.3 0.0049 0.39 13 37 .. 273 297 .. 256 298 .. 0.85 8 ? 6.7 0.0 0.91 74 3 20 .. 304 322 .. 302 323 .. 0.83 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.084 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W sp|Q9BVC4|LST8_HUMAN 14 ILATAGYDHTVRFW 27 5788888******* PP == domain 2 score: 13.7 bits; conditional E-value: 0.0053 EEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 c+rt H s v++l + pd +++a+++ +++r++d sp|Q9BVC4|LST8_HUMAN 34 CTRTVQ-HqdSQVNALEVTPDRSMIAAAG-YQHIRMYD 69 788875.75444**************99*.******98 PP == domain 3 score: 23.3 bits; conditional E-value: 4.9e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd sp|Q9BVC4|LST8_HUMAN 80 SYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 113 5555445688999********************9 PP == domain 4 score: 20.8 bits; conditional E-value: 3.2e-05 EEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtslafspdgawlasGsdDgtvriWd 38 qc+r++ ++++++ +p++a l+ G+ g ++iWd sp|Q9BVC4|LST8_HUMAN 120 QCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWD 156 8******9999*************************9 PP == domain 5 score: 5.1 bits; conditional E-value: 2.8 SEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 12 svtslafspdgawlasG.sdDgtvriWd 38 s+ts +pd +++a+ s g++++W+ sp|Q9BVC4|LST8_HUMAN 172 SITSAHIDPDASYMAAVnS-TGNCYVWN 198 389999*******997767.*******8 PP == domain 6 score: 23.7 bits; conditional E-value: 3.9e-06 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++fspd+++la++s D+t++iW sp|Q9BVC4|LST8_HUMAN 225 QCRFSPDSTLLATCSADQTCKIW 247 466******************** PP == domain 7 score: 13.8 bits; conditional E-value: 0.0049 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++afs d+++++++s D+ r+W sp|Q9BVC4|LST8_HUMAN 273 MWGCAFSGDSQYIVTASSDNLARLW 297 5899**********9988******* PP == domain 8 score: 6.7 bits; conditional E-value: 0.91 EEEEEESS.SSEEEEEEET CS WD40 3 clrtltGH.ssvtslafsp 20 r++ GH + v +laf++ sp|Q9BVC4|LST8_HUMAN 304 IKREYGGHqKAVVCLAFND 322 6789****99999**9976 PP >> sp|Q9NSI6|BRWD1_HUMAN Bromodomain and WD repeat-containing protein 1 OS=Homo sapiens GN=BRWD1 PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.5 1.3e-06 0.0001 7 38 .] 183 214 .. 175 214 .. 0.91 2 ! 22.0 0.0 1.3e-05 0.001 1 37 [. 218 255 .. 218 256 .. 0.92 3 ! 17.5 0.0 0.00034 0.028 3 37 .. 262 301 .. 260 302 .. 0.86 4 ? 6.3 0.0 1.2 99 17 37 .. 331 351 .. 319 351 .. 0.87 5 ! 20.5 0.0 4e-05 0.0032 4 37 .. 361 395 .. 358 396 .. 0.89 6 ? 6.9 0.0 0.76 61 13 38 .] 429 454 .. 418 454 .. 0.90 7 ! 14.3 0.1 0.0034 0.27 1 38 [] 458 497 .. 458 497 .. 0.75 8 ? 8.2 0.2 0.3 24 7 32 .. 513 536 .. 502 543 .. 0.78 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 1.3e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH s v+++af++ g+ +++GsdD+ v+iW+ sp|Q9NSI6|BRWD1_HUMAN 183 L-GHlSAVYCVAFDRTGHRIFTGSDDCLVKIWS 214 3.9*999*************************5 PP == domain 2 score: 22.0 bits; conditional E-value: 1.3e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l tl+GH ++++a++ +++++a+Gs D+ +r+W sp|Q9NSI6|BRWD1_HUMAN 218 GRLLSTLRGHsAEISDMAVNYENTMIAAGSCDKIIRVW 255 57899*****555****************99******* PP == domain 3 score: 17.5 bits; conditional E-value: 0.00034 EEEEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 ++ +l GH +s+tsl+fsp + +++G Dgtv +W sp|Q9NSI6|BRWD1_HUMAN 262 PVAVLQGHtGSITSLQFSPMAKGsqrymVSTGA-DGTVCFW 301 7889****888****988888889999666777.******* PP == domain 4 score: 6.3 bits; conditional E-value: 1.2 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 +fs g +la+Gs D+ +r++ sp|Q9NSI6|BRWD1_HUMAN 331 SFSVGGMFLATGSTDHVIRMY 351 5999999************86 PP == domain 5 score: 20.5 bits; conditional E-value: 4e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+ H + v s++f+ +g+ ++sGs+Dgt riW sp|Q9NSI6|BRWD1_HUMAN 361 IAELESHtDKVDSIQFCNNGDRFLSGSRDGTARIW 395 678999*555************************* PP == domain 6 score: 6.9 bits; conditional E-value: 0.76 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 vt +a++++ + ++++ D+ +++W+ sp|Q9NSI6|BRWD1_HUMAN 429 VTMIAWNQNDSIVVTAVNDHVLKVWN 454 77799**********988*******8 PP == domain 7 score: 14.3 bits; conditional E-value: 0.0034 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 gq+l+ l GH + v l ++p + l++G+ Dg++ iWd sp|Q9NSI6|BRWD1_HUMAN 458 GQLLHNLMGHaDEVFVLETHPFDSRimLSAGH-DGSIFIWD 497 689999****6669888866666663234566.*******9 PP == domain 8 score: 8.2 bits; conditional E-value: 0.3 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fs+dg+ +a ++ D sp|Q9NSI6|BRWD1_HUMAN 513 GQGHGAVFDCKFSQDGQHFA-CT-DS 536 469988************97.65.43 PP >> sp|Q6RI45-2|BRWD3_HUMAN Isoform 2 of Bromodomain and WD repeat-containing protein 3 OS=Homo sapiens GN=BRWD3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.4 3.6e-07 2.9e-05 7 37 .. 6 36 .. 2 36 .. 0.93 2 ! 22.7 0.0 7.5e-06 0.00061 1 37 [. 41 78 .. 41 79 .. 0.92 3 ! 17.0 0.1 0.0005 0.041 3 37 .. 85 124 .. 83 125 .. 0.81 4 ? 9.6 0.0 0.11 8.5 13 37 .. 150 174 .. 140 174 .. 0.89 5 ! 19.1 0.0 0.00011 0.0088 4 37 .. 184 220 .. 181 221 .. 0.84 6 ! 19.7 0.1 6.7e-05 0.0054 1 38 [] 284 323 .. 284 323 .. 0.71 7 ? 11.5 0.2 0.027 2.2 7 32 .. 339 362 .. 332 369 .. 0.80 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 3.6e-07 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH ssv+++af+++g+ +++GsdD+ v+iW sp|Q6RI45-2|BRWD3_HUMAN 6 L-GHlSSVYCVAFDRSGRRIFTGSDDCLVKIW 36 4.9***************************** PP == domain 2 score: 22.7 bits; conditional E-value: 7.5e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l tl+GH ++++a++ +++++a+Gs D+ vr+W sp|Q6RI45-2|BRWD3_HUMAN 41 GRLLATLRGHsAEISDMAVNYENTLIAAGSCDKVVRVW 78 57899*****555****************99******* PP == domain 3 score: 17.0 bits; conditional E-value: 0.0005 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriW 37 ++ +l GH s+ts++f+p+ + l+s + Dgt+ +W sp|Q6RI45-2|BRWD3_HUMAN 85 PVAVLQGHsASITSIQFCPSTKGtnryLTSTGADGTICFW 124 7889****777****977777667777986666******* PP == domain 4 score: 9.6 bits; conditional E-value: 0.11 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ +fs+ g ++++Gs D+ +ri+ sp|Q6RI45-2|BRWD3_HUMAN 150 ISCSSFSSGGMFITTGSTDHVIRIY 174 67778******************97 PP == domain 5 score: 19.1 bits; conditional E-value: 0.00011 EEEEESS.SSEEEEEEETTSSEE..EEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawl..asGsdDgtvriW 37 + +l+ H + v +++f+ +g+ l +sGs+Dgt riW sp|Q6RI45-2|BRWD3_HUMAN 184 IAELESHtDKVVAVQFCNNGDSLrfVSGSRDGTARIW 220 678999*55599***9******6559*********** PP == domain 6 score: 19.7 bits; conditional E-value: 6.7e-05 TEEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 gq+l+tl+GH + v l + d++ ++s++ Dg++ iWd sp|Q6RI45-2|BRWD3_HUMAN 284 GQLLHTLSGHdDEVFVLEaHPFDQRIILSAGHDGNIFIWD 323 799*******5557666633555555556555*******9 PP == domain 7 score: 11.5 bits; conditional E-value: 0.027 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fspdg+ +a ++ D sp|Q6RI45-2|BRWD3_HUMAN 339 GQGHGAVFDCKFSPDGNHFA-CT-DS 362 569988************97.66.54 PP >> tr|H0YAU9|H0YAU9_HUMAN Phospholipase A-2-activating protein (Fragment) OS=Homo sapiens GN=PLAA PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 1.2 98 19 37 .. 9 26 .. 3 26 .. 0.78 2 ! 20.3 0.6 4.6e-05 0.0037 3 37 .. 34 74 .. 32 75 .. 0.90 3 ! 24.3 0.2 2.4e-06 0.0002 3 37 .. 81 115 .. 80 115 .. 0.93 4 ! 29.2 0.0 6.6e-08 5.4e-06 2 38 .] 119 156 .. 118 156 .. 0.94 5 ! 17.6 0.0 0.00032 0.026 1 37 [. 158 194 .. 158 195 .. 0.89 6 ! 23.0 0.0 6.3e-06 0.00051 1 38 [] 198 236 .. 198 236 .. 0.81 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 1.2 ETTSSEEEEEETTSEEEEE CS WD40 19 spdgawlasGsdDgtvriW 37 p ga++ s s+D+t r+W tr|H0YAU9|H0YAU9_HUMAN 9 YPPGAFV-SVSRDRTTRLW 26 6788997.5788******* PP == domain 2 score: 20.3 bits; conditional E-value: 4.6e-05 EEEEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 ++ +GH ++v++++ p+++ +a+G+ D+++ i+ tr|H0YAU9|H0YAU9_HUMAN 34 EMHCMSGHsNFVSCVCIIPSSDIyphglIATGGNDHNICIF 74 578899**888*****99999999999889********997 PP == domain 3 score: 24.3 bits; conditional E-value: 2.4e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l++l+GH + v+sl+ + g++l sGs+D t ++W tr|H0YAU9|H0YAU9_HUMAN 81 PLYILKGHkNTVCSLSSGKFGTLL-SGSWDTTAKVW 115 6899****888****999999998.7********** PP == domain 4 score: 29.2 bits; conditional E-value: 6.6e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ tl GH v++++ p++ ++++Gs D+tv++W+ tr|H0YAU9|H0YAU9_HUMAN 119 KCMMTLQGHtAAVWAVKILPEQGLMLTGSADKTVKLWK 156 79*******777*************************6 PP == domain 5 score: 17.6 bits; conditional E-value: 0.00032 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+c rt++GH ++v++la ++ +l+ + D ++r W tr|H0YAU9|H0YAU9_HUMAN 158 GRCERTFSGHeDCVRGLAILSETEFLS-CANDASIRRW 194 689*******888************96.666****988 PP == domain 6 score: 23.0 bits; conditional E-value: 6.3e-06 TEEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 g+cl ++ GH + ++s++ f+ +++ + +D+++riW+ tr|H0YAU9|H0YAU9_HUMAN 198 GECLEVYYGHtNYIYSISvFPNCRDFV-TTAEDRSLRIWK 236 68********888*****666666665.5566*******6 PP >> tr|D6R9Z1|D6R9Z1_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.3 0.6 3.9e-10 3.2e-08 3 38 .] 41 77 .. 39 77 .. 0.93 2 ! 36.7 0.2 2.9e-10 2.4e-08 3 38 .] 83 119 .. 81 119 .. 0.93 3 ! 24.9 1.0 1.5e-06 0.00012 9 38 .] 132 164 .. 122 164 .. 0.83 4 ! 24.5 0.2 2.1e-06 0.00017 7 38 .] 174 206 .. 168 206 .. 0.86 5 ? 10.7 0.0 0.049 4 2 27 .. 211 236 .. 210 237 .] 0.81 Alignments for each domain: == domain 1 score: 36.3 bits; conditional E-value: 3.9e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6R9Z1|D6R9Z1_HUMAN 41 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 77 7899****667************99***********9 PP == domain 2 score: 36.7 bits; conditional E-value: 2.9e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|D6R9Z1|D6R9Z1_HUMAN 83 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 119 678899******************************8 PP == domain 3 score: 24.9 bits; conditional E-value: 1.5e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|D6R9Z1|D6R9Z1_HUMAN 132 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 164 79666*************989***********8 PP == domain 4 score: 24.5 bits; conditional E-value: 2.1e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd tr|D6R9Z1|D6R9Z1_HUMAN 174 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 206 3499666*************************9 PP == domain 5 score: 10.7 bits; conditional E-value: 0.049 EEEEEEESSSS.EEEEEEETTSSEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlas 27 ++l+tl+G + +++l+fsp+ wl++ tr|D6R9Z1|D6R9Z1_HUMAN 211 KHLYTLDGG-DiINALCFSPNRYWLCA 236 778888887.448***********975 PP >> sp|Q9UMS4|PRP19_HUMAN Pre-mRNA-processing factor 19 OS=Homo sapiens GN=PRPF19 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 0.99 80 13 38 .] 224 250 .. 208 250 .. 0.66 2 ! 30.3 0.0 3e-08 2.4e-06 2 38 .] 255 292 .. 254 292 .. 0.94 3 ! 17.9 0.1 0.00025 0.02 2 32 .. 297 328 .. 296 329 .. 0.92 4 ! 16.2 0.1 0.00087 0.07 12 38 .] 352 378 .. 338 378 .. 0.84 5 ! 33.7 0.0 2.5e-09 2e-07 3 38 .] 384 420 .. 382 420 .. 0.92 6 ! 15.1 0.1 0.002 0.16 3 37 .. 467 502 .. 465 503 .. 0.88 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.99 EEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 13 vtsla..fspdgawlasGsdDgtvriWd 38 + +l+ s+ ++ ++G+ D++v ++d sp|Q9UMS4|PRP19_HUMAN 224 ILALDlcPSDTNKI-LTGGADKNVVVFD 250 54444315555555.58999****9998 PP == domain 2 score: 30.3 bits; conditional E-value: 3e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q l tl+GH + vts+ f+p++++++s+s D t+riW+ sp|Q9UMS4|PRP19_HUMAN 255 QILATLKGHtKKVTSVVFHPSQDLVFSASPDATIRIWS 292 7799*****988*************************5 PP == domain 3 score: 17.9 bits; conditional E-value: 0.00025 EEEEEEESS.SSEEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDg 32 +c+++ ++H s vt+l+ + g++l+s+sdD+ sp|Q9UMS4|PRP19_HUMAN 297 SCVQVVRAHeSAVTGLSLHATGDYLLSSSDDQ 328 699******888*****************885 PP == domain 4 score: 16.2 bits; conditional E-value: 0.00087 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 s t+ +f+pdg + +G++D ++iWd sp|Q9UMS4|PRP19_HUMAN 352 SLTCAQFHPDGLIFGTGTMDSQIKIWD 378 589**********879999*******9 PP == domain 5 score: 33.7 bits; conditional E-value: 2.5e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ + GH +++ts+afs +g +la++ dD +v++Wd sp|Q9UMS4|PRP19_HUMAN 384 NVANFPGHsGPITSIAFSENGYYLATAADDSSVKLWD 420 67889***777****************99*******9 PP == domain 6 score: 15.1 bits; conditional E-value: 0.002 EEEEEESSSSE.EEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGHssv.tslafspdgawlasGsdDgtvriW 37 + ++t Hs+ t++af ++ +++as ++D++++++ sp|Q9UMS4|PRP19_HUMAN 467 EILHFTEHSGLtTGVAFGHHAKFIASTGMDRSLKFY 502 6789****99889***********98888*****98 PP >> sp|Q6RI45|BRWD3_HUMAN Bromodomain and WD repeat-containing protein 3 OS=Homo sapiens GN=BRWD3 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.1 0.4 3.1e-07 2.5e-05 6 37 .. 176 207 .. 169 207 .. 0.92 2 ! 22.6 0.0 8.4e-06 0.00068 1 37 [. 212 249 .. 212 250 .. 0.92 3 ! 16.8 0.1 0.00056 0.046 3 37 .. 256 295 .. 254 296 .. 0.81 4 ? 9.5 0.0 0.12 9.5 13 37 .. 321 345 .. 311 345 .. 0.89 5 ! 18.9 0.0 0.00012 0.0099 4 37 .. 355 391 .. 352 392 .. 0.84 6 ! 19.6 0.1 7.4e-05 0.006 1 38 [] 455 494 .. 455 494 .. 0.71 7 ? 11.3 0.2 0.031 2.5 7 32 .. 510 533 .. 503 540 .. 0.80 Alignments for each domain: == domain 1 score: 27.1 bits; conditional E-value: 3.1e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l GH ssv+++af+++g+ +++GsdD+ v+iW sp|Q6RI45|BRWD3_HUMAN 176 IL-GHlSSVYCVAFDRSGRRIFTGSDDCLVKIW 207 34.9***************************** PP == domain 2 score: 22.6 bits; conditional E-value: 8.4e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l tl+GH ++++a++ +++++a+Gs D+ vr+W sp|Q6RI45|BRWD3_HUMAN 212 GRLLATLRGHsAEISDMAVNYENTLIAAGSCDKVVRVW 249 57899*****555****************99******* PP == domain 3 score: 16.8 bits; conditional E-value: 0.00056 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvriW 37 ++ +l GH s+ts++f+p+ + l+s + Dgt+ +W sp|Q6RI45|BRWD3_HUMAN 256 PVAVLQGHsASITSIQFCPSTKGtnryLTSTGADGTICFW 295 7889****777****977777667777986666******* PP == domain 4 score: 9.5 bits; conditional E-value: 0.12 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ +fs+ g ++++Gs D+ +ri+ sp|Q6RI45|BRWD3_HUMAN 321 ISCSSFSSGGMFITTGSTDHVIRIY 345 67778******************97 PP == domain 5 score: 18.9 bits; conditional E-value: 0.00012 EEEEESS.SSEEEEEEETTSSEE..EEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawl..asGsdDgtvriW 37 + +l+ H + v +++f+ +g+ l +sGs+Dgt riW sp|Q6RI45|BRWD3_HUMAN 355 IAELESHtDKVVAVQFCNNGDSLrfVSGSRDGTARIW 391 678999*55599***9******6559*********** PP == domain 6 score: 19.6 bits; conditional E-value: 7.4e-05 TEEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 gq+l+tl+GH + v l + d++ ++s++ Dg++ iWd sp|Q6RI45|BRWD3_HUMAN 455 GQLLHTLSGHdDEVFVLEaHPFDQRIILSAGHDGNIFIWD 494 799*******5557666633555555556555*******9 PP == domain 7 score: 11.3 bits; conditional E-value: 0.031 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fspdg+ +a ++ D sp|Q6RI45|BRWD3_HUMAN 510 GQGHGAVFDCKFSPDGNHFA-CT-DS 533 569988************97.66.54 PP >> tr|H0YL19|H0YL19_HUMAN WD repeat-containing protein 61 OS=Homo sapiens GN=WDR61 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.087 7.1 14 29 .. 17 32 .. 9 38 .. 0.87 2 ! 20.9 0.0 3e-05 0.0024 11 38 .] 56 83 .. 45 83 .. 0.84 3 ! 38.7 0.0 6.7e-11 5.4e-09 1 38 [] 87 125 .. 87 125 .. 0.96 4 ! 31.5 1.5 1.3e-08 1.1e-06 5 38 .] 133 167 .. 129 167 .. 0.92 5 ! 19.7 0.7 7e-05 0.0056 2 38 .] 172 209 .. 171 209 .. 0.92 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.087 EEEEEETTSSEEEEEE CS WD40 14 tslafspdgawlasGs 29 + lafspd+++la+G+ tr|H0YL19|H0YL19_HUMAN 17 WTLAFSPDSQYLATGT 32 6799**********95 PP == domain 2 score: 20.9 bits; conditional E-value: 3e-05 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 +++ s+a+spdg++lasG Dg + i+d tr|H0YL19|H0YL19_HUMAN 56 KFILSIAYSPDGKYLASGAIDGIINIFD 83 5799**********************98 PP == domain 3 score: 38.7 bits; conditional E-value: 6.7e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l+tl+GH +++sl fspd+++l+++sdDg ++i+d tr|H0YL19|H0YL19_HUMAN 87 GKLLHTLEGHaMPIRSLTFSPDSQLLVTASDDGYIKIYD 125 689*******888*************************8 PP == domain 4 score: 31.5 bits; conditional E-value: 1.3e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tl+GH s+v +af+pd + ++s+s D++v++Wd tr|H0YL19|H0YL19_HUMAN 133 GTLSGHaSWVLNVAFCPDDTHFVSSSSDKSVKVWD 167 79****999*************99877*******9 PP == domain 5 score: 19.7 bits; conditional E-value: 7e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c++t+ H + v++++++ +g+ ++s +dD+ ++i+d tr|H0YL19|H0YL19_HUMAN 172 TCVHTFFDHqDQVWGVKYNGNGSKIVSVGDDQEIHIYD 209 79***999*666**************9999******98 PP >> sp|Q13033-2|STRN3_HUMAN Isoform Alpha of Striatin-3 OS=Homo sapiens GN=STRN3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.0 2.5e-07 2.1e-05 1 38 [] 386 424 .. 386 424 .. 0.94 2 ! 16.0 0.0 0.001 0.081 2 38 .] 440 477 .. 439 477 .. 0.95 3 ! 26.2 0.2 6e-07 4.9e-05 5 38 .] 496 530 .. 493 530 .. 0.92 4 ? 5.3 0.0 2.4 2e+02 11 38 .] 598 625 .. 585 625 .. 0.85 5 ! 34.2 0.1 1.9e-09 1.5e-07 2 38 .] 630 667 .. 629 667 .. 0.94 6 ! 13.3 0.0 0.0074 0.6 2 32 .. 672 707 .. 671 712 .. 0.85 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 2.5e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +tl+ H ++v++laf+p + l+++s+D+t+++W+ sp|Q13033-2|STRN3_HUMAN 386 WNPKYTLRSHfDGVRALAFHPVEPVLVTASEDHTLKLWN 424 57889*****777*************************8 PP == domain 2 score: 16.0 bits; conditional E-value: 0.001 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++t+++H ++v sla s++g +sG+ D t+ W+ sp|Q13033-2|STRN3_HUMAN 440 EPIYTFRAHiGPVLSLAISSNGEQCFSGGIDATIQWWN 477 5899*******************************998 PP == domain 3 score: 26.2 bits; conditional E-value: 6e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tl GH + v++la+s ++ l+s+s Dgtvr+W+ sp|Q13033-2|STRN3_HUMAN 496 GTLVGHtDAVWGLAYSGIKNQLLSCSADGTVRLWN 530 6899**666*************************8 PP == domain 4 score: 5.3 bits; conditional E-value: 2.4 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++++ + +p + +++++D++++++d sp|Q13033-2|STRN3_HUMAN 598 NHINRVVSHPTLPVTITAHEDRHIKFFD 625 45999999999999789********998 PP == domain 5 score: 34.2 bits; conditional E-value: 1.9e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++ +H + vtsla++p+g +l+sGs D+++r+W+ sp|Q13033-2|STRN3_HUMAN 630 KMIHSMVAHlDAVTSLAVDPNGIYLMSGSHDCSIRLWN 667 6789999**999****************99*******8 PP == domain 6 score: 13.3 bits; conditional E-value: 0.0074 EEEEEEESS.SS....EEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGH.ss....vtslafspdgawlasGsdDg 32 +c++++t+H + ++++af++++a++as++ D sp|Q13033-2|STRN3_HUMAN 672 TCVQEITAHrKKldesIYDVAFHSSKAYIASAGADA 707 6999*****9667889**************998886 PP >> tr|D6REE5|D6REE5_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 0.00017 0.013 4 38 .] 8 44 .. 5 44 .. 0.87 2 ! 35.7 0.6 6.1e-10 5e-08 3 38 .] 55 91 .. 53 91 .. 0.93 3 ! 23.3 1.5 5e-06 0.0004 9 38 .] 164 196 .. 155 196 .. 0.87 4 ! 23.9 0.2 3.2e-06 0.00026 7 38 .] 206 238 .. 200 238 .. 0.86 5 ! 22.7 0.1 7.6e-06 0.00061 2 38 .] 243 278 .. 242 278 .. 0.87 6 ? 5.3 0.0 2.4 1.9e+02 13 28 .. 304 319 .. 291 321 .] 0.86 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 0.00017 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s+s+D+t+ +W+ tr|D6REE5|D6REE5_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRDKTIIMWK 44 5799***666****99888888899***********6 PP == domain 2 score: 35.7 bits; conditional E-value: 6.1e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6REE5|D6REE5_HUMAN 55 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 91 7899****667************99***********9 PP == domain 3 score: 23.3 bits; conditional E-value: 5e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|D6REE5|D6REE5_HUMAN 164 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 196 57555*************989***********8 PP == domain 4 score: 23.9 bits; conditional E-value: 3.2e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd tr|D6REE5|D6REE5_HUMAN 206 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 238 3499666*************************9 PP == domain 5 score: 22.7 bits; conditional E-value: 7.6e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+tl+G + +++l+fsp+ wl++++ ++++iWd tr|D6REE5|D6REE5_HUMAN 243 KHLYTLDGG-DiINALCFSPNRYWLCAAT-GPSIKIWD 278 778888887.448************9888.*******9 PP == domain 6 score: 5.3 bits; conditional E-value: 2.4 EEEEEEETTSSEEEEE CS WD40 13 vtslafspdgawlasG 28 tsla+s dg+ l++G tr|D6REE5|D6REE5_HUMAN 304 CTSLAWSADGQTLFAG 319 59***********998 PP >> sp|Q9Y6I7-2|WSB1_HUMAN Isoform 2 of WD repeat and SOCS box-containing protein 1 OS=Homo sapiens GN=WSB1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.0 3.8e-07 3.1e-05 2 38 .] 15 53 .. 14 53 .. 0.83 2 ! 26.1 0.1 6.8e-07 5.5e-05 2 38 .] 59 96 .. 58 96 .. 0.91 3 ! 33.8 0.1 2.4e-09 1.9e-07 4 38 .] 103 138 .. 100 138 .. 0.92 4 ! 16.5 0.0 0.00072 0.058 11 37 .. 164 192 .. 145 193 .. 0.82 5 ! 18.2 0.2 0.0002 0.016 15 37 .. 210 232 .. 203 232 .. 0.93 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 3.8e-07 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 ++l l H+ v++l f pdg+++ +s+s+D+t+r+Wd sp|Q9Y6I7-2|WSB1_HUMAN 15 KLLLNLVDHTEvVRDLTFAPDGSLIlVSASRDKTLRVWD 53 6677788896657***********62589*********9 PP == domain 2 score: 26.1 bits; conditional E-value: 6.8e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++l+GH ++v+s+afspd+++l+s + + v +W+ sp|Q9Y6I7-2|WSB1_HUMAN 59 NMMKVLRGHqNWVYSCAFSPDSSMLCSVGASKAVFLWN 96 66899****999*************98777*******8 PP == domain 3 score: 33.8 bits; conditional E-value: 2.4e-09 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r+l+GH +v +++fspdga+la++s+D v+iWd sp|Q9Y6I7-2|WSB1_HUMAN 103 IRKLEGHhHDVVACDFSPDGALLATASYDTRVYIWD 138 7899***77799***********************9 PP == domain 4 score: 16.5 bits; conditional E-value: 0.00072 SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ss..vtslafspdgawlasGsdDgtvriW 37 ++ v+s++fs+dg +as dD+ vr+W sp|Q9Y6I7-2|WSB1_HUMAN 164 NDrwVRSVSFSHDGLHVASLADDKMVRFW 192 4467************985488******* PP == domain 5 score: 18.2 bits; conditional E-value: 0.0002 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++afs dg+ la+G+ Dg+v++W sp|Q9Y6I7-2|WSB1_HUMAN 210 CCAFSTDGSVLAAGTHDGSVYFW 232 999***********88******* PP >> sp|Q9Y3F4|STRAP_HUMAN Serine-threonine kinase receptor-associated protein OS=Homo sapiens GN=STRAP PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.0 0.079 6.4 5 33 .. 8 40 .. 4 43 .. 0.84 2 ? 12.5 0.3 0.013 1.1 4 38 .] 52 87 .. 49 87 .. 0.89 3 ! 20.8 0.0 3.1e-05 0.0025 4 38 .] 94 128 .. 91 128 .. 0.88 4 ! 19.0 0.0 0.00012 0.0095 6 38 .] 138 170 .. 134 170 .. 0.75 5 ? 8.4 0.0 0.26 21 3 34 .. 216 247 .. 214 251 .. 0.83 6 ! 39.5 0.0 3.9e-11 3.2e-09 2 37 .. 256 292 .. 255 293 .. 0.93 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.079 EEEESS.SSEEEEE...EETTSSEEEEEETTSE CS WD40 5 rtltGH.ssvtsla...fspdgawlasGsdDgt 33 t++GH +v +la p+g +l+s+++Dg+ sp|Q9Y3F4|STRAP_HUMAN 8 LTCSGHtRPVVDLAfsgITPYGYFLISACKDGK 40 5789**77799***8888999999*****9996 PP == domain 2 score: 12.5 bits; conditional E-value: 0.013 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++t+ GH + v++ ++d + a++ D t ++Wd sp|Q9Y3F4|STRAP_HUMAN 52 IGTFLGHkGAVWGATLNKDATKAATAAADFTAKVWD 87 67999**655*************99988*******9 PP == domain 3 score: 20.8 bits; conditional E-value: 3.1e-05 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 l tl +H++ v ++f +d+++l++G+ D+ +ri+d sp|Q9Y3F4|STRAP_HUMAN 94 LMTL-AHKHiVKTVDFTQDSNYLLTGGQDKLLRIYD 128 6676.898967************************8 PP == domain 4 score: 19.0 bits; conditional E-value: 0.00012 EEESS.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssv.tslafspdgawlasGsdDgtvriWd 38 +++GH s++ +l ++++ + ++s++ D+tvr+Wd sp|Q9Y3F4|STRAP_HUMAN 138 EISGHtSGIkKAL-WCSEDKQILSAD-DKTVRLWD 170 679**888*6666.555555556777.*******9 PP == domain 5 score: 8.4 bits; conditional E-value: 0.26 EEEEEESSSSEEEEEEETTSSEEEEEETTSEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtv 34 +++++++ ++s + +p++ +l++G++D ++ sp|Q9Y3F4|STRAP_HUMAN 216 PIKSFEAPATINSASLHPEKEFLVAGGEDFKL 247 6777877766*****************99876 PP == domain 6 score: 39.5 bits; conditional E-value: 3.9e-11 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + l +++GH +++++++fspdg + asGs+Dgt+r+W sp|Q9Y3F4|STRAP_HUMAN 256 EELESYKGHfGPIHCVRFSPDGELYASGSEDGTLRLW 292 67889****888************************* PP >> sp|Q676U5-5|A16L1_HUMAN Isoform 5 of Autophagy-related protein 16-1 OS=Homo sapiens GN=ATG16L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.8 0.0 4.4e-08 3.6e-06 5 37 .. 153 186 .. 150 187 .. 0.91 2 ! 13.8 0.0 0.0049 0.4 5 37 .. 197 230 .. 193 231 .. 0.87 3 ! 26.9 0.1 3.6e-07 2.9e-05 3 38 .] 237 273 .. 235 273 .. 0.91 4 ? 10.7 0.2 0.047 3.8 8 38 .] 285 312 .. 277 312 .. 0.62 5 ? 5.4 0.0 2.3 1.8e+02 13 37 .. 328 352 .. 320 353 .. 0.89 6 ! 19.3 0.1 9.2e-05 0.0075 13 38 .] 374 399 .. 360 399 .. 0.85 7 ! 14.1 0.4 0.0042 0.34 8 32 .. 411 436 .. 403 441 .. 0.74 Alignments for each domain: == domain 1 score: 29.8 bits; conditional E-value: 4.4e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++H + v++++fsp +++la+G++D+ v++W sp|Q676U5-5|A16L1_HUMAN 153 CVFDAHdGEVNAVQFSPGSRLLATGGMDRRVKLW 186 6799**666************************* PP == domain 2 score: 13.8 bits; conditional E-value: 0.0049 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l+G ++ts+ f++ g++l+++s D riW sp|Q676U5-5|A16L1_HUMAN 197 GSLSGSnAGITSIEFDSAGSYLLAASNDFASRIW 230 578888556**************9999******* PP == domain 3 score: 26.9 bits; conditional E-value: 3.6e-07 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + +tltGHs+ v s +f d+a ++sGs D+t+++Wd sp|Q676U5-5|A16L1_HUMAN 237 LRHTLTGHSGkVLSAKFLLDNARIVSGSHDRTLKLWD 273 5699****556****************99*******9 PP == domain 4 score: 10.7 bits; conditional E-value: 0.047 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 G +++ + + ++sG+ D+++r+Wd sp|Q676U5-5|A16L1_HUMAN 285 AGSscNDIVCT-----EQCVMSGHFDKKIRFWD 312 45543343222.....223679*99*******9 PP == domain 5 score: 5.4 bits; conditional E-value: 2.3 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +t+l+ +p+ + l+s+s+D +++ sp|Q676U5-5|A16L1_HUMAN 328 ITALDLNPERTELLSCSRDDLLKVI 352 99*****************999985 PP == domain 6 score: 19.3 bits; conditional E-value: 9.2e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 t + fspdg+++a+Gs g+++iW+ sp|Q676U5-5|A16L1_HUMAN 374 WTRVVFSPDGSYVAAGSAEGSLYIWS 399 68999********************5 PP == domain 7 score: 14.1 bits; conditional E-value: 0.0042 ESS.SSEEEEEEETTSSEEEEEETTS CS WD40 8 tGH.ssvtslafspdgawlasGsdDg 32 + H ss++++a+sp+g+ ++s ++ + sp|Q676U5-5|A16L1_HUMAN 411 KQHsSSINAVAWSPSGSHVVSVDKGC 436 379788************99755444 PP >> sp|Q13033|STRN3_HUMAN Striatin-3 OS=Homo sapiens GN=STRN3 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.2 0.0 2.9e-07 2.3e-05 1 38 [] 470 508 .. 470 508 .. 0.94 2 ! 15.8 0.0 0.0011 0.093 2 38 .] 524 561 .. 523 561 .. 0.95 3 ! 26.0 0.2 6.8e-07 5.5e-05 5 38 .] 580 614 .. 577 614 .. 0.92 4 ? 5.1 0.0 2.8 2.3e+02 11 38 .] 682 709 .. 670 709 .. 0.84 5 ! 34.0 0.1 2.1e-09 1.7e-07 2 38 .] 714 751 .. 713 751 .. 0.94 6 ! 13.1 0.0 0.0084 0.68 2 32 .. 756 791 .. 755 796 .. 0.85 Alignments for each domain: == domain 1 score: 27.2 bits; conditional E-value: 2.9e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +tl+ H ++v++laf+p + l+++s+D+t+++W+ sp|Q13033|STRN3_HUMAN 470 WNPKYTLRSHfDGVRALAFHPVEPVLVTASEDHTLKLWN 508 57889*****777*************************8 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0011 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++t+++H ++v sla s++g +sG+ D t+ W+ sp|Q13033|STRN3_HUMAN 524 EPIYTFRAHiGPVLSLAISSNGEQCFSGGIDATIQWWN 561 5899*******************************998 PP == domain 3 score: 26.0 bits; conditional E-value: 6.8e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tl GH + v++la+s ++ l+s+s Dgtvr+W+ sp|Q13033|STRN3_HUMAN 580 GTLVGHtDAVWGLAYSGIKNQLLSCSADGTVRLWN 614 6899**666*************************8 PP == domain 4 score: 5.1 bits; conditional E-value: 2.8 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++++ + +p + +++++D++++++d sp|Q13033|STRN3_HUMAN 682 NHINRVVSHPTLPVTITAHEDRHIKFFD 709 45999999999999789********998 PP == domain 5 score: 34.0 bits; conditional E-value: 2.1e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++ +H + vtsla++p+g +l+sGs D+++r+W+ sp|Q13033|STRN3_HUMAN 714 KMIHSMVAHlDAVTSLAVDPNGIYLMSGSHDCSIRLWN 751 6789999**999****************99*******8 PP == domain 6 score: 13.1 bits; conditional E-value: 0.0084 EEEEEEESS.SS....EEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGH.ss....vtslafspdgawlasGsdDg 32 +c++++t+H + ++++af++++a++as++ D sp|Q13033|STRN3_HUMAN 756 TCVQEITAHrKKldesIYDVAFHSSKAYIASAGADA 791 6999*****9667889**************998886 PP >> tr|B4DIH4|B4DIH4_HUMAN POC1 centriolar protein homolog B OS=Homo sapiens GN=POC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.7 0.2 1.4e-10 1.1e-08 5 38 .] 8 42 .. 4 42 .. 0.85 2 ! 22.7 0.3 7.9e-06 0.00064 13 38 .] 59 84 .. 46 84 .. 0.73 3 ! 34.1 0.2 1.9e-09 1.6e-07 2 36 .. 89 124 .. 88 126 .. 0.90 4 ! 26.4 0.0 5.2e-07 4.2e-05 2 37 .. 131 167 .. 130 168 .. 0.93 Alignments for each domain: == domain 1 score: 37.7 bits; conditional E-value: 1.4e-10 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l H +v++ +fspdg++++s+s+D+t++iWd tr|B4DIH4|B4DIH4_HUMAN 8 YSLYRHtHWVRCAKFSPDGRLIVSCSEDKTIKIWD 42 555556336*************************9 PP == domain 2 score: 22.7 bits; conditional E-value: 7.9e-06 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + ++f+p+g+ +as++ D+tv++Wd tr|B4DIH4|B4DIH4_HUMAN 59 ANFVDFNPSGTCIASAGSDQTVKVWD 84 46688********97655*******9 PP == domain 3 score: 34.1 bits; conditional E-value: 1.9e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++l+++ H ++v++++f+p+g++l+++s Dgt++i tr|B4DIH4|B4DIH4_HUMAN 89 KLLQHYQVHsGGVNCISFHPSGNYLITASSDGTLKI 124 6899*****666**************9988*****9 PP == domain 4 score: 26.4 bits; conditional E-value: 5.2e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++tl GH ++v ++fs+ g ++asG+ D v +W tr|B4DIH4|B4DIH4_HUMAN 131 RLIYTLQGHtGPVFTVSFSKGGELFASGGADTQVLLW 167 6899*****888************************* PP >> sp|P57737|CORO7_HUMAN Coronin-7 OS=Homo sapiens GN=CORO7 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 0.1 3e-08 2.5e-06 4 37 .. 70 105 .. 67 106 .. 0.88 2 ? 4.9 0.0 3.2 2.6e+02 16 38 .] 132 154 .. 123 154 .. 0.76 3 ! 14.8 0.0 0.0025 0.2 2 38 .] 159 196 .. 158 196 .. 0.88 4 ? 10.7 0.0 0.047 3.8 12 37 .. 546 572 .. 538 573 .. 0.85 5 ! 22.9 0.0 6.8e-06 0.00055 4 38 .] 587 623 .. 584 623 .. 0.85 6 ! 23.9 0.0 3.2e-06 0.00026 7 37 .. 633 664 .. 629 665 .. 0.90 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 3e-08 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriW 37 + +l Hs+ vt+l+fsp ++l a+Gs D+tv++W sp|P57737|CORO7_HUMAN 70 VAHLGCHSDlVTDLDFSPFDDFLlATGSADRTVKLW 105 678999*8889***********7369********** PP == domain 2 score: 4.9 bits; conditional E-value: 3.2 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 l+f+p ++ ++ + tv++Wd sp|P57737|CORO7_HUMAN 132 LQFHPTSDGILVSAAGTTVKVWD 154 567888888654444*******9 PP == domain 3 score: 14.8 bits; conditional E-value: 0.0025 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 q+l++l +H++ v s +s+dga++ ++++D+ +ri+d sp|P57737|CORO7_HUMAN 159 QPLTELAAHGDlVQSAVWSRDGALVGTACKDKQLRIFD 196 89999****77899999*******856789******98 PP == domain 4 score: 10.7 bits; conditional E-value: 0.047 SEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriW 37 vt+la++p + la +++D +r+W sp|P57737|CORO7_HUMAN 546 AVTDLAWDPFDPHrLAVAGEDARIRLW 572 49***********9887888******* PP == domain 5 score: 22.9 bits; conditional E-value: 6.8e-06 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ltGH ++sl+f+p a ++ s+s+D tvriWd sp|P57737|CORO7_HUMAN 587 ETVLTGHtEKICSLRFHPLAANVLaSSSYDLTVRIWD 623 5789***666************7527789*******9 PP == domain 6 score: 23.9 bits; conditional E-value: 3.2e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH + + sla+spdg+ la+ ++Dg vr++ sp|P57737|CORO7_HUMAN 633 LQGHqDQIFSLAWSPDGQQLATVCKDGRVRVY 664 78**666***************9*******98 PP >> tr|H0Y8W2|H0Y8W2_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.8 3.8e-05 0.0031 19 38 .] 3 22 .. 1 22 [. 0.94 2 ! 36.4 0.2 3.6e-10 2.9e-08 3 38 .] 28 64 .. 26 64 .. 0.93 3 ! 24.6 1.0 1.9e-06 0.00016 9 38 .] 77 109 .. 67 109 .. 0.83 4 ! 24.2 0.2 2.5e-06 0.00021 7 38 .] 119 151 .. 113 151 .. 0.86 5 ! 23.0 0.1 6e-06 0.00049 2 38 .] 156 191 .. 155 191 .. 0.87 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 3.8e-05 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 s+dg++ +sGs+Dgt+r+Wd tr|H0Y8W2|H0Y8W2_HUMAN 3 SSDGQFALSGSWDGTLRLWD 22 89****99***********9 PP == domain 2 score: 36.4 bits; conditional E-value: 3.6e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|H0Y8W2|H0Y8W2_HUMAN 28 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 64 678899******************************8 PP == domain 3 score: 24.6 bits; conditional E-value: 1.9e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|H0Y8W2|H0Y8W2_HUMAN 77 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 109 79666*************989***********8 PP == domain 4 score: 24.2 bits; conditional E-value: 2.5e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd tr|H0Y8W2|H0Y8W2_HUMAN 119 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 151 3499666*************************9 PP == domain 5 score: 23.0 bits; conditional E-value: 6e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+tl+G + +++l+fsp+ wl++++ ++++iWd tr|H0Y8W2|H0Y8W2_HUMAN 156 KHLYTLDGG-DiINALCFSPNRYWLCAAT-GPSIKIWD 191 778888887.448************9888.*******9 PP >> sp|Q9GZL7|WDR12_HUMAN Ribosome biogenesis protein WDR12 OS=Homo sapiens GN=WDR12 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.3 0.02 1.6 13 38 .] 104 127 .. 95 127 .. 0.77 2 ! 15.7 0.2 0.0013 0.1 2 37 .. 131 170 .. 130 171 .. 0.77 3 ! 23.7 1.9 3.8e-06 0.00031 3 38 .] 181 217 .. 179 217 .. 0.94 4 ! 24.7 0.5 1.8e-06 0.00014 3 38 .] 249 284 .. 247 284 .. 0.86 5 ! 24.6 0.1 1.9e-06 0.00015 3 38 .] 290 325 .. 288 325 .. 0.90 6 ! 23.9 1.0 3.3e-06 0.00027 6 38 .] 337 371 .. 334 371 .. 0.92 7 ? 9.2 0.0 0.15 12 3 35 .. 378 410 .. 376 413 .. 0.81 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.02 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++s+ w+++Gs+D+t riW+ sp|Q9GZL7|WDR12_HUMAN 104 ISSI--KGAEEWILTGSYDKTSRIWS 127 5555..445689*************5 PP == domain 2 score: 15.7 bits; conditional E-value: 0.0013 EEEEEEESSSS.EEEEEEETTSSE...EEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgaw...lasGsdDgtvriW 37 + + t+ GH++ v ++a+ + ++ l+s+s+D+t+ +W sp|Q9GZL7|WDR12_HUMAN 131 KSIMTIVGHTDvVKDVAWVKKDSLsclLLSASMDQTILLW 170 6678889**885699955555555887789999******* PP == domain 3 score: 23.7 bits; conditional E-value: 3.8e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+ ++GH +sv s+a++ +g+ ++sGs+D+ ++iW+ sp|Q9GZL7|WDR12_HUMAN 181 ALHCCRGHaGSVDSIAVDGSGTKFCSGSWDKMLKIWS 217 58999***999*************************5 PP == domain 4 score: 24.7 bits; conditional E-value: 1.8e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ tl+GH v+s+ +s+ +s+s+D+t+r+Wd sp|Q9GZL7|WDR12_HUMAN 249 PIVTLSGHmEAVSSVLWSDAEEI-CSASWDHTIRVWD 284 7789****999****77777777.789*********9 PP == domain 5 score: 24.6 bits; conditional E-value: 1.9e-06 EEEEEESSSSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHssv.tslafspdgawlasGsdDgtvriWd 38 + tltG v +++++sp + lasGs D+++r+Wd sp|Q9GZL7|WDR12_HUMAN 290 LKSTLTGN-KVfNCISYSPLCKRLASGSTDRHIRLWD 325 56789999.688************************9 PP == domain 6 score: 23.9 bits; conditional E-value: 3.3e-06 EEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +lt H ++vts+++sp + l+sGs D+ v++Wd sp|Q9GZL7|WDR12_HUMAN 337 SLTSHtGWVTSVKWSPTHEQqLISGSLDNIVKLWD 371 6899*888************999***********9 PP == domain 7 score: 9.2 bits; conditional E-value: 0.15 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvr 35 +l+ l +H + v s+++ + g +l sG+ D++++ sp|Q9GZL7|WDR12_HUMAN 378 PLYDLAAHeDKVLSVDWTDTGLLL-SGGADNKLY 410 6777889*666****999999997.7998*9875 PP >> sp|Q676U5-2|A16L1_HUMAN Isoform 2 of Autophagy-related protein 16-1 OS=Homo sapiens GN=ATG16L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 0.0 6.3e-08 5.1e-06 5 37 .. 297 330 .. 294 331 .. 0.91 2 ! 13.3 0.0 0.007 0.57 5 37 .. 341 374 .. 337 375 .. 0.87 3 ! 26.4 0.1 5.1e-07 4.1e-05 3 38 .] 381 417 .. 379 417 .. 0.91 4 ? 10.3 0.2 0.066 5.3 8 38 .] 429 456 .. 421 456 .. 0.62 5 ? 4.9 0.0 3.2 2.6e+02 13 37 .. 472 496 .. 464 497 .. 0.89 6 ! 18.8 0.1 0.00013 0.011 13 38 .] 518 543 .. 504 543 .. 0.85 7 ! 13.6 0.4 0.006 0.48 8 32 .. 555 580 .. 547 585 .. 0.74 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 6.3e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++H + v++++fsp +++la+G++D+ v++W sp|Q676U5-2|A16L1_HUMAN 297 CVFDAHdGEVNAVQFSPGSRLLATGGMDRRVKLW 330 6799**666************************* PP == domain 2 score: 13.3 bits; conditional E-value: 0.007 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l+G ++ts+ f++ g++l+++s D riW sp|Q676U5-2|A16L1_HUMAN 341 GSLSGSnAGITSIEFDSAGSYLLAASNDFASRIW 374 578888556**************9999******* PP == domain 3 score: 26.4 bits; conditional E-value: 5.1e-07 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + +tltGHs+ v s +f d+a ++sGs D+t+++Wd sp|Q676U5-2|A16L1_HUMAN 381 LRHTLTGHSGkVLSAKFLLDNARIVSGSHDRTLKLWD 417 5699****556****************99*******9 PP == domain 4 score: 10.3 bits; conditional E-value: 0.066 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 G +++ + + ++sG+ D+++r+Wd sp|Q676U5-2|A16L1_HUMAN 429 AGSscNDIVCT-----EQCVMSGHFDKKIRFWD 456 45533343222.....223679*99*******9 PP == domain 5 score: 4.9 bits; conditional E-value: 3.2 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +t+l+ +p+ + l+s+s+D +++ sp|Q676U5-2|A16L1_HUMAN 472 ITALDLNPERTELLSCSRDDLLKVI 496 99*****************999985 PP == domain 6 score: 18.8 bits; conditional E-value: 0.00013 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 t + fspdg+++a+Gs g+++iW+ sp|Q676U5-2|A16L1_HUMAN 518 WTRVVFSPDGSYVAAGSAEGSLYIWS 543 68999********************5 PP == domain 7 score: 13.6 bits; conditional E-value: 0.006 ESS.SSEEEEEEETTSSEEEEEETTS CS WD40 8 tGH.ssvtslafspdgawlasGsdDg 32 + H ss++++a+sp+g+ ++s ++ + sp|Q676U5-2|A16L1_HUMAN 555 KQHsSSINAVAWSPSGSHVVSVDKGC 580 379788************99755444 PP >> tr|B4DYB5|B4DYB5_HUMAN Sperm-associated antigen 16 protein OS=Homo sapiens GN=SPAG16 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.085 6.9 6 33 .. 253 281 .. 248 284 .. 0.82 2 ! 26.0 1.9 7.1e-07 5.7e-05 9 38 .] 298 328 .. 289 328 .. 0.85 3 ! 28.7 3.9 9.8e-08 7.9e-06 1 38 [] 332 370 .. 332 370 .. 0.94 4 ! 29.2 0.1 7e-08 5.7e-06 2 38 .] 375 412 .. 374 412 .. 0.93 5 ! 14.8 0.2 0.0025 0.2 3 38 .] 418 454 .. 416 454 .. 0.93 6 ! 20.1 0.1 5.1e-05 0.0041 4 37 .. 502 536 .. 500 537 .] 0.91 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.085 EEESS.SSEEEEEEETTSSEEEEEETTSE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgt 33 +++ H +v++++ +p+++ l+s+++D+ tr|B4DYB5|B4DYB5_HUMAN 253 IFRLHeLPVSCVSMQPHKDILVSCGEDRL 281 56668667*****************9986 PP == domain 2 score: 26.0 bits; conditional E-value: 7.1e-07 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++ ++++f+p+g+ la++s D tv++Wd tr|B4DYB5|B4DYB5_HUMAN 298 GHtDWLSDCCFHPSGDKLATSSGDTTVKLWD 328 9*7779*************9978*******9 PP == domain 3 score: 28.7 bits; conditional E-value: 9.8e-08 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g+c+ t++GHs v+s+ +++ g+++as+s D+t +iWd tr|B4DYB5|B4DYB5_HUMAN 332 GDCILTFEGHSRaVWSCTWHSCGNFVASSSLDKTSKIWD 370 689*******446*************************9 PP == domain 4 score: 29.2 bits; conditional E-value: 7e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c tl GH +sv+s+ f p ++ l+++s D+t+ iWd tr|B4DYB5|B4DYB5_HUMAN 375 RCRCTLYGHtDSVNSIEFFPFSNTLLTSSADKTLSIWD 412 688999***888****************99*******9 PP == domain 5 score: 14.8 bits; conditional E-value: 0.0025 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++l GH s+++ f+p g+++as++ g ++Wd tr|B4DYB5|B4DYB5_HUMAN 418 CEQSLYGHmHSINDAIFDPRGHMIASCDACGVTKLWD 454 789999**999****************99*******9 PP == domain 6 score: 20.1 bits; conditional E-value: 5.1e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++l GH + + + fs+dg l+sG+ Dgtvr W tr|B4DYB5|B4DYB5_HUMAN 502 IHKLMGHeNEAHTVVFSHDGEILFSGGSDGTVRTW 536 68888**9999***************88*****99 PP >> sp|Q676U5|A16L1_HUMAN Autophagy-related protein 16-1 OS=Homo sapiens GN=ATG16L1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 0.0 6.5e-08 5.3e-06 5 37 .. 316 349 .. 313 350 .. 0.91 2 ! 13.3 0.0 0.0073 0.59 5 37 .. 360 393 .. 356 394 .. 0.87 3 ! 26.4 0.1 5.3e-07 4.3e-05 3 38 .] 400 436 .. 398 436 .. 0.91 4 ? 10.2 0.2 0.068 5.5 8 38 .] 448 475 .. 440 475 .. 0.62 5 ? 4.9 0.0 3.3 2.7e+02 13 37 .. 491 515 .. 483 516 .. 0.89 6 ! 18.8 0.1 0.00014 0.011 13 38 .] 537 562 .. 523 562 .. 0.85 7 ! 13.5 0.4 0.0062 0.5 8 32 .. 574 599 .. 566 604 .. 0.74 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 6.5e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++H + v++++fsp +++la+G++D+ v++W sp|Q676U5|A16L1_HUMAN 316 CVFDAHdGEVNAVQFSPGSRLLATGGMDRRVKLW 349 6799**666************************* PP == domain 2 score: 13.3 bits; conditional E-value: 0.0073 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l+G ++ts+ f++ g++l+++s D riW sp|Q676U5|A16L1_HUMAN 360 GSLSGSnAGITSIEFDSAGSYLLAASNDFASRIW 393 578888556**************9999******* PP == domain 3 score: 26.4 bits; conditional E-value: 5.3e-07 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + +tltGHs+ v s +f d+a ++sGs D+t+++Wd sp|Q676U5|A16L1_HUMAN 400 LRHTLTGHSGkVLSAKFLLDNARIVSGSHDRTLKLWD 436 5699****556****************99*******9 PP == domain 4 score: 10.2 bits; conditional E-value: 0.068 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 G +++ + + ++sG+ D+++r+Wd sp|Q676U5|A16L1_HUMAN 448 AGSscNDIVCT-----EQCVMSGHFDKKIRFWD 475 45533343222.....223679*99*******9 PP == domain 5 score: 4.9 bits; conditional E-value: 3.3 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +t+l+ +p+ + l+s+s+D +++ sp|Q676U5|A16L1_HUMAN 491 ITALDLNPERTELLSCSRDDLLKVI 515 99*****************999985 PP == domain 6 score: 18.8 bits; conditional E-value: 0.00014 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 t + fspdg+++a+Gs g+++iW+ sp|Q676U5|A16L1_HUMAN 537 WTRVVFSPDGSYVAAGSAEGSLYIWS 562 68999********************5 PP == domain 7 score: 13.5 bits; conditional E-value: 0.0062 ESS.SSEEEEEEETTSSEEEEEETTS CS WD40 8 tGH.ssvtslafspdgawlasGsdDg 32 + H ss++++a+sp+g+ ++s ++ + sp|Q676U5|A16L1_HUMAN 574 KQHsSSINAVAWSPSGSHVVSVDKGC 599 379788************99755444 PP >> sp|P57737-3|CORO7_HUMAN Isoform 3 of Coronin-7 OS=Homo sapiens GN=CORO7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.1 0.1 3.5e-08 2.9e-06 4 37 .. 70 105 .. 67 106 .. 0.88 2 ? 4.7 0.0 3.7 3e+02 16 38 .] 132 154 .. 123 154 .. 0.76 3 ! 14.6 0.0 0.0029 0.23 2 38 .] 159 196 .. 158 196 .. 0.88 4 ? 10.5 0.0 0.054 4.4 12 37 .. 546 572 .. 538 573 .. 0.85 5 ! 22.7 0.0 7.9e-06 0.00064 4 38 .] 587 623 .. 584 623 .. 0.85 6 ! 23.7 0.0 3.6e-06 0.0003 7 37 .. 633 664 .. 629 665 .. 0.90 Alignments for each domain: == domain 1 score: 30.1 bits; conditional E-value: 3.5e-08 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriW 37 + +l Hs+ vt+l+fsp ++l a+Gs D+tv++W sp|P57737-3|CORO7_HUMAN 70 VAHLGCHSDlVTDLDFSPFDDFLlATGSADRTVKLW 105 678999*8889***********7369********** PP == domain 2 score: 4.7 bits; conditional E-value: 3.7 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 l+f+p ++ ++ + tv++Wd sp|P57737-3|CORO7_HUMAN 132 LQFHPTSDGILVSAAGTTVKVWD 154 567888888654444*******9 PP == domain 3 score: 14.6 bits; conditional E-value: 0.0029 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 q+l++l +H++ v s +s+dga++ ++++D+ +ri+d sp|P57737-3|CORO7_HUMAN 159 QPLTELAAHGDlVQSAVWSRDGALVGTACKDKQLRIFD 196 89999****77899999*******856789******98 PP == domain 4 score: 10.5 bits; conditional E-value: 0.054 SEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriW 37 vt+la++p + la +++D +r+W sp|P57737-3|CORO7_HUMAN 546 AVTDLAWDPFDPHrLAVAGEDARIRLW 572 49***********9887888******* PP == domain 5 score: 22.7 bits; conditional E-value: 7.9e-06 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ltGH ++sl+f+p a ++ s+s+D tvriWd sp|P57737-3|CORO7_HUMAN 587 ETVLTGHtEKICSLRFHPLAANVLaSSSYDLTVRIWD 623 5789***666************7527789*******9 PP == domain 6 score: 23.7 bits; conditional E-value: 3.6e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH + + sla+spdg+ la+ ++Dg vr++ sp|P57737-3|CORO7_HUMAN 633 LQGHqDQIFSLAWSPDGQQLATVCKDGRVRVY 664 78**666***************9*******98 PP >> tr|H0YI78|H0YI78_HUMAN Kinesin-like protein KIF21A (Fragment) OS=Homo sapiens GN=KIF21A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.3 2.5e-07 2e-05 2 38 .] 319 354 .. 318 354 .. 0.95 2 ? 12.2 0.1 0.016 1.3 1 38 [] 358 395 .. 358 395 .. 0.95 3 ? 11.5 0.0 0.027 2.2 5 38 .] 427 459 .. 423 459 .. 0.88 4 ! 20.0 0.0 5.4e-05 0.0044 2 38 .] 464 504 .. 463 504 .. 0.93 5 ? 6.4 0.0 1.1 89 9 38 .] 522 550 .. 513 550 .. 0.71 6 ! 14.7 0.1 0.0027 0.22 4 38 .] 558 593 .. 556 593 .. 0.90 7 ! 23.1 0.0 5.7e-06 0.00046 3 38 .] 599 633 .. 597 633 .. 0.79 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 2.5e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+++ +GH + v ++ ++ ++l++Gs+D+t+++W+ tr|H0YI78|H0YI78_HUMAN 319 QCIHIAEGHtKAVLCV--DSTDDLLFTGSKDRTCKVWN 354 8********999****..99999999***********8 PP == domain 2 score: 12.2 bits; conditional E-value: 0.016 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq + +l GH ++v s++++ + +++++ s +++Wd tr|H0YI78|H0YI78_HUMAN 358 GQEIMSLGGHpNNVVSVKYCNYTSLVFTVS-TSYIKVWD 395 678999****99999***************.*******9 PP == domain 3 score: 11.5 bits; conditional E-value: 0.027 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 + +G + ++ +a +p g++l ++s + vr+Wd tr|H0YI78|H0YI78_HUMAN 427 AIPSGENQINQIALNPTGTFLYAAS-GNAVRMWD 459 56677788*****************.*******9 PP == domain 4 score: 20.0 bits; conditional E-value: 5.4e-05 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 q +++ltGH ++v +l s+ ++++++Gs+D+ ++++d tr|H0YI78|H0YI78_HUMAN 464 QSTGKLTGHlGPVMCLTvdqISSGQDLIITGSKDHYIKMFD 504 567889********************************998 PP == domain 5 score: 6.4 bits; conditional E-value: 1.1 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l + d+ l+sGs+D+ ++ Wd tr|H0YI78|H0YI78_HUMAN 522 PHyDGIEALTIQGDN--LFSGSRDNGIKKWD 550 566668888555554..559**********9 PP == domain 6 score: 14.7 bits; conditional E-value: 0.0027 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +H ++v++l + pd++ l+sG++ g +++W+ tr|H0YI78|H0YI78_HUMAN 558 QQVPNAHkDWVCALGVVPDHPVLLSGCRGGILKVWN 593 567789*666*************************8 PP == domain 7 score: 23.1 bits; conditional E-value: 5.7e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +GH s+++++++ +++ ++++ dD+tvriW+ tr|H0YI78|H0YI78_HUMAN 599 PVGEMKGHdSPINAICV--NSTHIFTAADDRTVRIWK 633 678899**888998865..5555558888*******6 PP >> tr|E7EVC7|E7EVC7_HUMAN Autophagy-related protein 16-1 OS=Homo sapiens GN=ATG16L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 0.0 6.7e-08 5.5e-06 5 37 .. 333 366 .. 330 367 .. 0.91 2 ! 13.2 0.0 0.0076 0.61 5 37 .. 377 410 .. 373 411 .. 0.87 3 ! 26.3 0.1 5.5e-07 4.4e-05 3 38 .] 417 453 .. 415 453 .. 0.91 4 ? 10.2 0.2 0.071 5.7 8 38 .] 465 492 .. 457 492 .. 0.62 5 ? 4.8 0.0 3.5 2.8e+02 13 37 .. 508 532 .. 500 533 .. 0.89 6 ! 18.7 0.1 0.00014 0.011 13 38 .] 554 579 .. 540 579 .. 0.85 7 ! 13.5 0.4 0.0064 0.52 8 32 .. 591 616 .. 583 621 .. 0.74 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 6.7e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++H + v++++fsp +++la+G++D+ v++W tr|E7EVC7|E7EVC7_HUMAN 333 CVFDAHdGEVNAVQFSPGSRLLATGGMDRRVKLW 366 6799**666************************* PP == domain 2 score: 13.2 bits; conditional E-value: 0.0076 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l+G ++ts+ f++ g++l+++s D riW tr|E7EVC7|E7EVC7_HUMAN 377 GSLSGSnAGITSIEFDSAGSYLLAASNDFASRIW 410 578888556**************9999******* PP == domain 3 score: 26.3 bits; conditional E-value: 5.5e-07 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + +tltGHs+ v s +f d+a ++sGs D+t+++Wd tr|E7EVC7|E7EVC7_HUMAN 417 LRHTLTGHSGkVLSAKFLLDNARIVSGSHDRTLKLWD 453 5699****556****************99*******9 PP == domain 4 score: 10.2 bits; conditional E-value: 0.071 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 G +++ + + ++sG+ D+++r+Wd tr|E7EVC7|E7EVC7_HUMAN 465 AGSscNDIVCT-----EQCVMSGHFDKKIRFWD 492 45533343222.....223679*99*******9 PP == domain 5 score: 4.8 bits; conditional E-value: 3.5 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +t+l+ +p+ + l+s+s+D +++ tr|E7EVC7|E7EVC7_HUMAN 508 ITALDLNPERTELLSCSRDDLLKVI 532 99*****************999985 PP == domain 6 score: 18.7 bits; conditional E-value: 0.00014 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 t + fspdg+++a+Gs g+++iW+ tr|E7EVC7|E7EVC7_HUMAN 554 WTRVVFSPDGSYVAAGSAEGSLYIWS 579 68999********************5 PP == domain 7 score: 13.5 bits; conditional E-value: 0.0064 ESS.SSEEEEEEETTSSEEEEEETTS CS WD40 8 tGH.ssvtslafspdgawlasGsdDg 32 + H ss++++a+sp+g+ ++s ++ + tr|E7EVC7|E7EVC7_HUMAN 591 KQHsSSINAVAWSPSGSHVVSVDKGC 616 379788************99755444 PP >> sp|Q8WWQ0|PHIP_HUMAN PH-interacting protein OS=Homo sapiens GN=PHIP PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.6 0.1 2e-06 0.00016 6 37 .. 179 210 .. 173 210 .. 0.92 2 ! 21.1 0.0 2.5e-05 0.002 1 37 [. 215 252 .. 215 253 .. 0.93 3 ! 17.8 0.2 0.00028 0.023 3 37 .. 259 298 .. 257 298 .. 0.86 4 ? 8.5 0.0 0.24 20 17 37 .. 328 348 .. 320 348 .. 0.88 5 ! 19.5 0.0 7.9e-05 0.0064 4 37 .. 358 392 .. 355 393 .. 0.88 6 ? 12.6 0.0 0.012 0.98 1 38 [] 456 495 .. 456 495 .. 0.81 7 ? 7.5 0.3 0.48 39 7 32 .. 511 534 .. 502 541 .. 0.78 Alignments for each domain: == domain 1 score: 24.6 bits; conditional E-value: 2e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l GH ssv+++ f++ g+ +++GsdD+ v+iW sp|Q8WWQ0|PHIP_HUMAN 179 IL-GHlSSVYCVTFDRTGRRIFTGSDDCLVKIW 210 44.9***************************** PP == domain 2 score: 21.1 bits; conditional E-value: 2.5e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l tl+GH ++++a++ +++++a+Gs D+ +r+W sp|Q8WWQ0|PHIP_HUMAN 215 GRLLATLRGHaAEISDMAVNYENTMIAAGSCDKMIRVW 252 57899*****777****************99******* PP == domain 3 score: 17.8 bits; conditional E-value: 0.00028 EEEEEESS.SSEEEEE....EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtsla....fspdgawlasGsdDgtvriW 37 +l +l GH s+tsl+ s ++++l+s + Dgt+ +W sp|Q8WWQ0|PHIP_HUMAN 259 PLAVLQGHsASITSLQfsplCSGSKRYLSSTGADGTICFW 298 7899****777****999999999999986667******* PP == domain 4 score: 8.5 bits; conditional E-value: 0.24 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 +fs g +la+Gs D+ +r++ sp|Q8WWQ0|PHIP_HUMAN 328 SFSAGGMFLATGSTDHIIRVY 348 599****************97 PP == domain 5 score: 19.5 bits; conditional E-value: 7.9e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+ H + v s++fs ++ ++sGs+Dgt riW sp|Q8WWQ0|PHIP_HUMAN 358 ISELEFHtDKVDSIQFSNTSNRFVSGSRDGTARIW 392 677899*555************************* PP == domain 6 score: 12.6 bits; conditional E-value: 0.012 TEEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 gq++++l GH + v l +p + ++ s++ Dg+v +Wd sp|Q8WWQ0|PHIP_HUMAN 456 GQLIHVLMGHeDEVFVLEPHPFDPRVLfSAGHDGNVIVWD 495 6899******777*999988888886445545*******9 PP == domain 7 score: 7.5 bits; conditional E-value: 0.48 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++ spdg+ +a ++ D sp|Q8WWQ0|PHIP_HUMAN 511 GQGHGAVFDCKCSPDGQHFA-CT-DS 534 469988************97.65.43 PP >> sp|Q6IA86|ELP2_HUMAN Elongator complex protein 2 OS=Homo sapiens GN=ELP2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.3 0.0093 0.76 4 37 .. 51 90 .. 48 91 .. 0.71 2 ? 8.3 0.0 0.28 23 6 38 .] 102 143 .. 98 143 .. 0.69 3 ? 7.2 0.0 0.6 49 4 37 .. 152 190 .. 150 190 .. 0.73 4 ! 18.5 0.3 0.00017 0.014 2 38 .] 198 237 .. 197 237 .. 0.85 5 ? 10.9 0.0 0.042 3.4 5 37 .. 277 319 .. 274 319 .. 0.80 6 ! 16.2 0.0 0.00091 0.073 4 36 .. 381 414 .. 378 416 .. 0.84 7 ? 5.1 0.0 2.8 2.3e+02 4 29 .. 560 586 .. 557 600 .. 0.83 8 ! 16.6 0.0 0.00065 0.052 2 38 .] 605 642 .. 604 642 .. 0.86 9 ! 23.7 1.8 3.7e-06 0.0003 7 37 .. 665 696 .. 660 696 .. 0.88 10 ? 5.7 0.0 1.9 1.5e+02 24 36 .. 804 818 .. 769 820 .. 0.83 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0093 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 ++ l GH v++++ sp+ ++ sG+ D+ v W sp|Q6IA86|ELP2_HUMAN 51 VTNLNGHtARVNCIQwickqdGSPSTELV-SGGSDNQVIHW 90 56789**6669999555555566666665.6766**99988 PP == domain 2 score: 8.3 bits; conditional E-value: 0.28 EEESS.SSEEEEE.......EETTSSE...EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgaw...lasGsdDgtvriWd 38 +l GH ++v+++ +p + ++s+ D vr+W+ sp|Q6IA86|ELP2_HUMAN 102 HLQGHeGPVYAVHavyqrrtSDPA--LctlIVSAAADSAVRLWS 143 789**8888888655566443333..2555567777*******5 PP == domain 3 score: 7.2 bits; conditional E-value: 0.6 EEEEE.SS.SSE.EEEEEETTSSE..EEEEETTSEEEEE CS WD40 4 lrtlt.GH.ssv.tslafspdgaw..lasGsdDgtvriW 37 l+tl G + +l+f p+ + la+G dD+ ++i+ sp|Q6IA86|ELP2_HUMAN 152 LQTLNfGNgFALaLCLSFLPNTDVpiLACGNDDCRIHIF 190 55555455333446999999999998888989****995 PP == domain 4 score: 18.5 bits; conditional E-value: 0.00017 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 q++ +l GH ++++++ w las+s D+ +riW+ sp|Q6IA86|ELP2_HUMAN 198 QKVLSLCGHeDWIRGV------EWaafgrdlfLASCSQDCLIRIWK 237 6677889**888****......887777778889***********6 PP == domain 5 score: 10.9 bits; conditional E-value: 0.042 EEEESS.SSEEEEE....EETTSSE.....EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla....fspdgaw.....lasGsdDgtvriW 37 ++l GH ++v+++ f +dg + l+s+s+D+t +W sp|Q6IA86|ELP2_HUMAN 277 TVLAGHeNWVNAVHwqpvFYKDGVLqqpvrLLSASMDKTMILW 319 5688**999****555555555555*****889999****999 PP == domain 6 score: 16.2 bits; conditional E-value: 0.00091 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++GH ++v +l ++p+g ++++ + D+t r+ sp|Q6IA86|ELP2_HUMAN 381 EIVISGHfDGVQDLVWDPEGEFIITVGTDQTTRL 414 56789**777************997666***998 PP == domain 7 score: 5.1 bits; conditional E-value: 2.8 EEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGs 29 +++l GH+ + ++ ++++++las++ sp|Q6IA86|ELP2_HUMAN 560 VQKLYGHGYeIFCVTCNSSKTLLASAC 586 67889**446*************9886 PP == domain 8 score: 16.6 bits; conditional E-value: 0.00065 EEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 ++++ l H s vt +afsp+ ++l++ s+D+t +W+ sp|Q6IA86|ELP2_HUMAN 605 KQVQNLVFH-SltVTQMAFSPNEKFLLAVSRDRTWSLWK 642 667778889.446**************99*********6 PP == domain 9 score: 23.7 bits; conditional E-value: 3.7e-06 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 + Hs ++s+++spd++++++Gs+D++v +W sp|Q6IA86|ELP2_HUMAN 665 TSVHSRiIWSCDWSPDSKYFFTGSRDKKVVVW 696 46796667************************ PP == domain 10 score: 5.7 bits; conditional E-value: 1.9 E..EEEEETTSEEEE CS WD40 24 w..lasGsdDgtvri 36 w +as+++D+tv+i sp|Q6IA86|ELP2_HUMAN 804 WlhFASCGEDHTVKI 818 5335999*******9 PP >> tr|Q8IU52|Q8IU52_HUMAN POC1 centriolar protein homolog B OS=Homo sapiens GN=TUWD12 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.9 0.2 2.6e-10 2.1e-08 5 38 .] 8 42 .. 4 42 .. 0.85 2 ! 21.8 0.3 1.5e-05 0.0012 13 38 .] 59 84 .. 46 84 .. 0.73 3 ! 33.3 0.2 3.6e-09 2.9e-07 2 36 .. 89 124 .. 88 126 .. 0.90 4 ! 25.6 0.0 9.7e-07 7.9e-05 2 37 .. 131 167 .. 130 168 .. 0.93 Alignments for each domain: == domain 1 score: 36.9 bits; conditional E-value: 2.6e-10 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l H +v++ +fspdg++++s+s+D+t++iWd tr|Q8IU52|Q8IU52_HUMAN 8 YSLYRHtHWVRCAKFSPDGRLIVSCSEDKTIKIWD 42 555556336*************************9 PP == domain 2 score: 21.8 bits; conditional E-value: 1.5e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + ++f+p+g+ +as++ D+tv++Wd tr|Q8IU52|Q8IU52_HUMAN 59 ANFVDFNPSGTCIASAGSDQTVKVWD 84 46688********97655*******9 PP == domain 3 score: 33.3 bits; conditional E-value: 3.6e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++l+++ H ++v++++f+p+g++l+++s Dgt++i tr|Q8IU52|Q8IU52_HUMAN 89 KLLQHYQVHsGGVNCISFHPSGNYLITASSDGTLKI 124 6899*****666**************9988*****9 PP == domain 4 score: 25.6 bits; conditional E-value: 9.7e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++tl GH ++v ++fs+ g ++asG+ D v +W tr|Q8IU52|Q8IU52_HUMAN 131 RLIYTLQGHtGPVFTVSFSKGGELFASGGADTQVLLW 167 6899*****888************************* PP >> sp|Q9NVX2-2|NLE1_HUMAN Isoform 2 of Notchless protein homolog 1 OS=Homo sapiens GN=NLE1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.31 25 25 38 .] 52 65 .. 37 65 .. 0.86 2 ! 31.1 0.0 1.7e-08 1.4e-06 2 38 .] 71 108 .. 70 108 .. 0.91 3 ! 35.7 0.2 6.1e-10 4.9e-08 1 38 [] 112 150 .. 112 150 .. 0.94 4 ! 35.4 0.0 7.5e-10 6.1e-08 6 37 .. 159 191 .. 154 192 .. 0.90 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.31 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 l+sGsdD t+ +W+ sp|Q9NVX2-2|NLE1_HUMAN 52 LVSGSDDFTLFLWS 65 789**********5 PP == domain 2 score: 31.1 bits; conditional E-value: 1.7e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+ tGH+ ++ + fspd++ +as+s D+++++Wd sp|Q9NVX2-2|NLE1_HUMAN 71 KPLTRMTGHQAlINQVLFSPDSRIVASASFDKSIKLWD 108 6788899**6679***************99*******9 PP == domain 3 score: 35.7 bits; conditional E-value: 6.1e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+ l +l+GH v+ +a+s d+++l+sGs D t+++Wd sp|Q9NVX2-2|NLE1_HUMAN 112 GKYLASLRGHvAAVYQIAWSADSRLLVSGSSDSTLKVWD 150 57899*****999****************99*******9 PP == domain 4 score: 35.4 bits; conditional E-value: 7.5e-10 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH + v+++++spdg+ +asG++D+ +riW sp|Q9NVX2-2|NLE1_HUMAN 159 DLPGHaDEVYAVDWSPDGQRVASGGKDKCLRIW 191 588**777************************* PP >> sp|Q6IA86-2|ELP2_HUMAN Isoform 2 of Elongator complex protein 2 OS=Homo sapiens GN=ELP2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.3 0.0084 0.68 4 37 .. 51 90 .. 48 91 .. 0.71 2 ? 8.4 0.0 0.25 20 6 38 .] 102 143 .. 98 143 .. 0.69 3 ! 18.6 0.3 0.00015 0.012 2 38 .] 172 211 .. 171 211 .. 0.85 4 ? 11.0 0.0 0.038 3.1 5 37 .. 251 293 .. 248 293 .. 0.80 5 ! 16.3 0.0 0.00081 0.066 4 36 .. 311 344 .. 308 346 .. 0.84 6 ? 5.2 0.0 2.5 2.1e+02 4 29 .. 490 516 .. 487 530 .. 0.83 7 ! 16.8 0.0 0.00058 0.047 2 38 .] 535 572 .. 534 572 .. 0.86 8 ! 23.9 1.8 3.3e-06 0.00027 7 37 .. 595 626 .. 590 626 .. 0.88 9 ? 5.8 0.0 1.7 1.4e+02 24 36 .. 734 748 .. 699 750 .. 0.83 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.0084 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 ++ l GH v++++ sp+ ++ sG+ D+ v W sp|Q6IA86-2|ELP2_HUMAN 51 VTNLNGHtARVNCIQwickqdGSPSTELV-SGGSDNQVIHW 90 56789**6669999555555566666665.6766**99988 PP == domain 2 score: 8.4 bits; conditional E-value: 0.25 EEESS.SSEEEEE.......EETTSSE...EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgaw...lasGsdDgtvriWd 38 +l GH ++v+++ +p + ++s+ D vr+W+ sp|Q6IA86-2|ELP2_HUMAN 102 HLQGHeGPVYAVHavyqrrtSDPA--LctlIVSAAADSAVRLWS 143 789**8888888655566443333..2555567777*******5 PP == domain 3 score: 18.6 bits; conditional E-value: 0.00015 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 q++ +l GH ++++++ w las+s D+ +riW+ sp|Q6IA86-2|ELP2_HUMAN 172 QKVLSLCGHeDWIRGV------EWaafgrdlfLASCSQDCLIRIWK 211 6677889**888****......887777778889***********6 PP == domain 4 score: 11.0 bits; conditional E-value: 0.038 EEEESS.SSEEEEE....EETTSSE.....EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla....fspdgaw.....lasGsdDgtvriW 37 ++l GH ++v+++ f +dg + l+s+s+D+t +W sp|Q6IA86-2|ELP2_HUMAN 251 TVLAGHeNWVNAVHwqpvFYKDGVLqqpvrLLSASMDKTMILW 293 5688**999****555555555555*****889999****999 PP == domain 5 score: 16.3 bits; conditional E-value: 0.00081 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++GH ++v +l ++p+g ++++ + D+t r+ sp|Q6IA86-2|ELP2_HUMAN 311 EIVISGHfDGVQDLVWDPEGEFIITVGTDQTTRL 344 56789**777************997666***998 PP == domain 6 score: 5.2 bits; conditional E-value: 2.5 EEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGs 29 +++l GH+ + ++ ++++++las++ sp|Q6IA86-2|ELP2_HUMAN 490 VQKLYGHGYeIFCVTCNSSKTLLASAC 516 67889**446*************9886 PP == domain 7 score: 16.8 bits; conditional E-value: 0.00058 EEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 ++++ l H s vt +afsp+ ++l++ s+D+t +W+ sp|Q6IA86-2|ELP2_HUMAN 535 KQVQNLVFH-SltVTQMAFSPNEKFLLAVSRDRTWSLWK 572 667778889.446**************99*********6 PP == domain 8 score: 23.9 bits; conditional E-value: 3.3e-06 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 + Hs ++s+++spd++++++Gs+D++v +W sp|Q6IA86-2|ELP2_HUMAN 595 TSVHSRiIWSCDWSPDSKYFFTGSRDKKVVVW 626 46796667************************ PP == domain 9 score: 5.8 bits; conditional E-value: 1.7 E..EEEEETTSEEEE CS WD40 24 w..lasGsdDgtvri 36 w +as+++D+tv+i sp|Q6IA86-2|ELP2_HUMAN 734 WlhFASCGEDHTVKI 748 5335999*******9 PP >> tr|D6RFX4|D6RFX4_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.7 0.6 2.8e-10 2.3e-08 3 38 .] 14 50 .. 12 50 .. 0.93 2 ! 37.1 0.2 2.1e-10 1.7e-08 3 38 .] 56 92 .. 54 92 .. 0.93 3 ! 25.4 1.0 1.1e-06 9e-05 9 38 .] 105 137 .. 95 137 .. 0.83 4 ! 25.0 0.2 1.5e-06 0.00012 7 38 .] 147 179 .. 141 179 .. 0.86 Alignments for each domain: == domain 1 score: 36.7 bits; conditional E-value: 2.8e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6RFX4|D6RFX4_HUMAN 14 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 50 7899****667************99***********9 PP == domain 2 score: 37.1 bits; conditional E-value: 2.1e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|D6RFX4|D6RFX4_HUMAN 56 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 92 678899******************************8 PP == domain 3 score: 25.4 bits; conditional E-value: 1.1e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|D6RFX4|D6RFX4_HUMAN 105 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 137 79666*************989***********8 PP == domain 4 score: 25.0 bits; conditional E-value: 1.5e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd tr|D6RFX4|D6RFX4_HUMAN 147 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 179 3499666*************************9 PP >> tr|B4DNJ6|B4DNJ6_HUMAN Serine-threonine kinase receptor-associated protein OS=Homo sapiens GN=STRAP PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.1 1.2 1e+02 5 29 .. 8 36 .. 4 52 .. 0.80 2 ? 12.4 0.3 0.014 1.1 4 38 .] 65 100 .. 62 100 .. 0.89 3 ! 20.7 0.0 3.3e-05 0.0026 4 38 .] 107 141 .. 104 141 .. 0.88 4 ! 18.9 0.0 0.00012 0.01 6 38 .] 151 183 .. 147 183 .. 0.75 5 ? 8.3 0.0 0.27 22 3 34 .. 229 260 .. 227 264 .. 0.83 6 ! 39.4 0.0 4.1e-11 3.3e-09 2 37 .. 269 305 .. 268 306 .. 0.93 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 1.2 EEEESS.SSEEEEE...EETTSSEEEEEE CS WD40 5 rtltGH.ssvtsla...fspdgawlasGs 29 t++GH +v +la p+g +l+s++ tr|B4DNJ6|B4DNJ6_HUMAN 8 LTCSGHtRPVVDLAfsgITPYGYFLISAC 36 5789**77799**9778888888888876 PP == domain 2 score: 12.4 bits; conditional E-value: 0.014 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++t+ GH + v++ ++d + a++ D t ++Wd tr|B4DNJ6|B4DNJ6_HUMAN 65 IGTFLGHkGAVWGATLNKDATKAATAAADFTAKVWD 100 67999**655*************99988*******9 PP == domain 3 score: 20.7 bits; conditional E-value: 3.3e-05 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 l tl +H++ v ++f +d+++l++G+ D+ +ri+d tr|B4DNJ6|B4DNJ6_HUMAN 107 LMTL-AHKHiVKTVDFTQDSNYLLTGGQDKLLRIYD 141 6676.898967************************8 PP == domain 4 score: 18.9 bits; conditional E-value: 0.00012 EEESS.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssv.tslafspdgawlasGsdDgtvriWd 38 +++GH s++ +l ++++ + ++s++ D+tvr+Wd tr|B4DNJ6|B4DNJ6_HUMAN 151 EISGHtSGIkKAL-WCSEDKQILSAD-DKTVRLWD 183 679**888*6666.555555556777.*******9 PP == domain 5 score: 8.3 bits; conditional E-value: 0.27 EEEEEESSSSEEEEEEETTSSEEEEEETTSEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtv 34 +++++++ ++s + +p++ +l++G++D ++ tr|B4DNJ6|B4DNJ6_HUMAN 229 PIKSFEAPATINSASLHPEKEFLVAGGEDFKL 260 6777777766*****************99876 PP == domain 6 score: 39.4 bits; conditional E-value: 4.1e-11 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + l +++GH +++++++fspdg + asGs+Dgt+r+W tr|B4DNJ6|B4DNJ6_HUMAN 269 EELESYKGHfGPIHCVRFSPDGELYASGSEDGTLRLW 305 67889****888************************* PP >> sp|Q9BRX9|WDR83_HUMAN WD repeat domain-containing protein 83 OS=Homo sapiens GN=WDR83 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.0 2.9e-06 0.00023 4 38 .] 18 53 .. 15 53 .. 0.80 2 ! 22.8 0.2 7.1e-06 0.00057 2 38 .] 58 95 .. 57 95 .. 0.91 3 ! 25.5 0.1 1e-06 8.4e-05 1 38 [] 99 137 .. 99 137 .. 0.94 4 ? 6.6 0.0 0.96 78 3 36 .. 145 177 .. 143 179 .. 0.77 5 ? 11.7 0.1 0.023 1.9 5 36 .. 187 217 .. 183 219 .. 0.78 6 ! 19.2 0.0 0.0001 0.0081 1 38 [] 223 263 .. 223 263 .. 0.82 7 ? 4.5 0.0 4.4 3.6e+02 13 37 .. 280 303 .. 273 304 .. 0.87 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 2.9e-06 EEEEE.SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GHssvtslafspdgawlasGsdDgtvriWd 38 l+tl+ G++ v++++f+ dg++ ++++ D+t+++W+ sp|Q9BRX9|WDR83_HUMAN 18 LKTLDcGQGAVRAVRFNVDGNYCLTCGSDKTLKLWN 53 6666656667************776655*******8 PP == domain 2 score: 22.8 bits; conditional E-value: 7.1e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++lrt++GH+ v + a s d++ l+sG+ D+ v +Wd sp|Q9BRX9|WDR83_HUMAN 58 TLLRTYSGHGYeVLDAAGSFDNSSLCSGGGDKAVVLWD 95 689******446****************88*******9 PP == domain 3 score: 25.5 bits; conditional E-value: 1e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq +r+++GH + v+ ++f+ + + ++sGs D ++r Wd sp|Q9BRX9|WDR83_HUMAN 99 GQVVRKFRGHaGKVNTVQFNEEATVILSGSIDSSIRCWD 137 6889******777*************************9 PP == domain 4 score: 6.6 bits; conditional E-value: 0.96 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++tl+ ++v+s+++s++ + +Gs Dg vr sp|Q9BRX9|WDR83_HUMAN 145 PVQTLDEArDGVSSVKVSDHEIL--AGSVDGRVRR 177 67777777677999988888777..6*******95 PP == domain 5 score: 11.7 bits; conditional E-value: 0.023 EEEESSSSEEEEEEETTSSE.EEEEETTSEEEE CS WD40 5 rtltGHssvtslafspdgaw.lasGsdDgtvri 36 + G ++t+ +fs+dg+ l+ +s D t+r+ sp|Q9BRX9|WDR83_HUMAN 187 SDYVGS-PITCTCFSRDGQCtLV-SSLDSTLRL 217 456666.8************766.566****98 PP == domain 6 score: 19.2 bits; conditional E-value: 0.0001 TEEEEEEESS.SS...E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss...v.tslafspdgawlasGsdDgtvriWd 38 g++l++++GH + ++ s + ++s+s+Dg+v +Wd sp|Q9BRX9|WDR83_HUMAN 223 GELLGEYKGHkNQeykLdCC--LSERDTHVVSCSEDGKVFFWD 263 57899*****6558988444..4888888899**********9 PP == domain 7 score: 4.5 bits; conditional E-value: 4.4 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 v sla++p + l++++ g+v W sp|Q9BRX9|WDR83_HUMAN 280 VQSLAYHPTEPCLLTAM-GGSVQCW 303 79************999.9999999 PP >> sp|Q8N0X2|SPG16_HUMAN Sperm-associated antigen 16 protein OS=Homo sapiens GN=SPAG16 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.0 0.1 8.4 6 33 .. 347 375 .. 342 378 .. 0.82 2 ! 25.7 1.9 8.6e-07 7e-05 9 38 .] 392 422 .. 383 422 .. 0.85 3 ! 28.4 3.9 1.2e-07 9.7e-06 1 38 [] 426 464 .. 426 464 .. 0.94 4 ! 28.9 0.1 8.6e-08 6.9e-06 2 38 .] 469 506 .. 468 506 .. 0.93 5 ! 14.5 0.2 0.0031 0.25 3 38 .] 512 548 .. 510 548 .. 0.93 6 ! 19.8 0.1 6.2e-05 0.005 4 37 .. 596 630 .. 594 631 .] 0.91 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.1 EEESS.SSEEEEEEETTSSEEEEEETTSE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgt 33 +++ H +v++++ +p+++ l+s+++D+ sp|Q8N0X2|SPG16_HUMAN 347 IFRLHeLPVSCVSMQPHKDILVSCGEDRL 375 56668667*****************9986 PP == domain 2 score: 25.7 bits; conditional E-value: 8.6e-07 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++ ++++f+p+g+ la++s D tv++Wd sp|Q8N0X2|SPG16_HUMAN 392 GHtDWLSDCCFHPSGDKLATSSGDTTVKLWD 422 9*7779*************9978*******9 PP == domain 3 score: 28.4 bits; conditional E-value: 1.2e-07 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g+c+ t++GHs v+s+ +++ g+++as+s D+t +iWd sp|Q8N0X2|SPG16_HUMAN 426 GDCILTFEGHSRaVWSCTWHSCGNFVASSSLDKTSKIWD 464 689*******446*************************9 PP == domain 4 score: 28.9 bits; conditional E-value: 8.6e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c tl GH +sv+s+ f p ++ l+++s D+t+ iWd sp|Q8N0X2|SPG16_HUMAN 469 RCRCTLYGHtDSVNSIEFFPFSNTLLTSSADKTLSIWD 506 688999***888****************99*******9 PP == domain 5 score: 14.5 bits; conditional E-value: 0.0031 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++l GH s+++ f+p g+++as++ g ++Wd sp|Q8N0X2|SPG16_HUMAN 512 CEQSLYGHmHSINDAIFDPRGHMIASCDACGVTKLWD 548 789999**999****************99*******9 PP == domain 6 score: 19.8 bits; conditional E-value: 6.2e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++l GH + + + fs+dg l+sG+ Dgtvr W sp|Q8N0X2|SPG16_HUMAN 596 IHKLMGHeNEAHTVVFSHDGEILFSGGSDGTVRTW 630 67888**9999***************88*****99 PP >> sp|Q8N1V2-2|WDR16_HUMAN Isoform 2 of WD repeat-containing protein 16 OS=Homo sapiens GN=WDR16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 0.001 0.081 4 38 .] 67 107 .. 64 107 .. 0.76 2 ! 17.1 0.0 0.00047 0.038 5 38 .] 115 151 .. 111 151 .. 0.82 3 ? 4.9 0.0 3.2 2.6e+02 25 37 .. 184 195 .. 169 196 .. 0.79 4 ? 6.3 0.0 1.2 98 8 37 .. 339 369 .. 308 370 .. 0.80 5 ? 10.2 0.0 0.072 5.8 9 37 .. 425 454 .. 416 455 .. 0.83 6 ! 16.4 0.0 0.00078 0.063 7 38 .] 467 499 .. 461 499 .. 0.90 7 ! 16.8 0.1 0.00055 0.044 4 38 .] 547 583 .. 544 583 .. 0.86 8 ! 15.7 0.1 0.0012 0.1 3 37 .. 589 624 .. 587 625 .. 0.85 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 0.001 EEEEESS.SSEEEEEEETTSSEEEEE.....ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.....sdDgtvriWd 38 + l GH ++v++la s++g ++asG + + + +Wd sp|Q8N1V2-2|WDR16_HUMAN 67 QNFLQGHgNNVSCLAISRSGEYIASGqvtfmGFKADIILWD 107 56689**999**************97543332377777776 PP == domain 2 score: 17.1 bits; conditional E-value: 0.00047 EEEESSSS.EEEEEEETTSSEEEE.EE.TTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlas.Gs.dDgtvriWd 38 l+ H++ + +lafsp+ +l+s G+ dDg+v +W+ sp|Q8N1V2-2|WDR16_HUMAN 115 ARLSLHKGkIEALAFSPNDLYLVSlGGpDDGSVVVWS 151 556679555*************9877788*******5 PP == domain 3 score: 4.9 bits; conditional E-value: 3.2 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 +++++ +gt+r+W sp|Q8N1V2-2|WDR16_HUMAN 184 FMTAG-NGTIRVW 195 45899.******* PP == domain 4 score: 6.3 bits; conditional E-value: 1.2 ESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGsdDgtvriW 37 t H + v ++ f+ a l a++ ++ +r+W sp|Q8N1V2-2|WDR16_HUMAN 339 TCHfDAVEDIVFPFGTAELfATCA-KKDIRVW 369 578555999987777777625667.******* PP == domain 5 score: 10.2 bits; conditional E-value: 0.072 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +vt++a+ +d + ++sG+ g vr+W sp|Q8N1V2-2|WDR16_HUMAN 425 AHrIGVTAIATTSDCKRVISGGGEGEVRVW 454 674349****999999999*988******* PP == domain 6 score: 16.4 bits; conditional E-value: 0.00078 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+ H ssv+++++ +++ +++s Dgt+ iWd sp|Q8N1V2-2|WDR16_HUMAN 467 LKEHkSSVSCIRVKRNNEECVTASTDGTCIIWD 499 789*888************999999*******9 PP == domain 7 score: 16.8 bits; conditional E-value: 0.00055 EEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 +r+l+G s+ +++++ ++g +++G+ D+ v++Wd sp|Q8N1V2-2|WDR16_HUMAN 547 IRELEGSlSGsINGMDITQEGVHFVTGGNDHLVKVWD 583 67788888444*************************9 PP == domain 8 score: 15.7 bits; conditional E-value: 0.0012 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++ GH +++t ++ sp +++++s s Dg + W sp|Q8N1V2-2|WDR16_HUMAN 589 VTHVGVGHsGNITRIRISPGNQYIVSVSADGAILRW 624 577888**655**************9999**99777 PP >> sp|O43379|WDR62_HUMAN WD repeat-containing protein 62 OS=Homo sapiens GN=WDR62 PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.0 0.00029 0.024 2 38 .] 102 141 .. 101 141 .. 0.90 2 ? 11.1 0.0 0.036 2.9 6 38 .] 150 185 .. 145 185 .. 0.80 3 ? 8.6 0.1 0.22 18 13 37 .. 201 224 .. 192 224 .. 0.88 4 ? 4.8 0.0 3.4 2.8e+02 15 37 .. 302 320 .. 292 321 .. 0.75 5 ! 13.2 0.1 0.0076 0.62 15 38 .] 364 387 .. 348 387 .. 0.84 6 ! 14.6 0.0 0.0029 0.23 18 38 .] 422 441 .. 399 441 .. 0.74 7 ? 7.8 0.0 0.41 33 16 36 .. 498 518 .. 474 520 .. 0.83 8 ? 9.7 0.0 0.1 8.3 4 35 .. 573 606 .. 570 607 .. 0.83 9 ? 4.7 0.0 3.8 3.1e+02 8 38 .] 621 656 .. 615 656 .. 0.72 10 ? 9.5 0.1 0.11 9.3 7 37 .. 666 700 .. 660 701 .. 0.68 11 ? 11.6 0.7 0.025 2 1 37 [. 705 742 .. 705 743 .. 0.85 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 0.00029 EEEEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++++++ + +s ++lafspdg+++++G + + vriWd sp|O43379|WDR62_HUMAN 102 KQQHIFNTArKSLSALAFSPDGKYIVTGenGHRPAVRIWD 141 678999988899***************98866*******9 PP == domain 2 score: 11.1 bits; conditional E-value: 0.036 EEESSSS.EEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlas.G..sdDgtvriWd 38 + GH+ v ++afsp+ + ++s G + D + +Wd sp|O43379|WDR62_HUMAN 150 EMLGHKYgVACVAFSPNMKHIVSmGyqH-DMVLNVWD 185 5569*555************99656444.*******9 PP == domain 3 score: 8.6 bits; conditional E-value: 0.22 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 v +l+fs d++++++ + +++vr+W sp|O43379|WDR62_HUMAN 201 VIALSFSEDSSYFVTVG-NRHVRFW 224 45899**********9*.******* PP == domain 4 score: 4.8 bits; conditional E-value: 3.4 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ ++ ++++G+ Dg vri+ sp|O43379|WDR62_HUMAN 302 CV----SQELIFCGCTDGIVRIF 320 33....5566779999*****97 PP == domain 5 score: 13.2 bits; conditional E-value: 0.0076 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +l f+p ++wl++ +D++++iWd sp|O43379|WDR62_HUMAN 364 ALTFDPIHQWLSCVYKDHSIYIWD 387 788*******976699*******9 PP == domain 6 score: 14.6 bits; conditional E-value: 0.0029 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 p+g++l+++s D+t+r+W+ sp|O43379|WDR62_HUMAN 422 CLPSGSFLTCSS-DNTIRFWN 441 679****98777.*******8 PP == domain 7 score: 7.8 bits; conditional E-value: 0.41 EEEETTSSEEEEEETTSEEEE CS WD40 16 lafspdgawlasGsdDgtvri 36 +++spdg+ lasG++ g++ri sp|O43379|WDR62_HUMAN 498 MQVSPDGQHLASGDRSGNLRI 518 458**********99**9998 PP == domain 8 score: 9.7 bits; conditional E-value: 0.1 EEEEESS.SSEEEEEEETTSSE.EEEEETTSEEE CS WD40 4 lrtltGH.ssvtslafspdgaw.lasGsdDgtvr 35 +tl+ H ss+t+++f + + ++s++ D++++ sp|O43379|WDR62_HUMAN 573 EQTLDDHsSSITAIKFAGNRDIqMISCGADKSIY 606 679999*888****999999999667777***96 PP == domain 9 score: 4.7 bits; conditional E-value: 3.8 ESS..SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ss...vtslafspdgawlasGsdDgtvriWd 38 ++H ++++ + ++++a ++ D++vr+++ sp|O43379|WDR62_HUMAN 621 RTHhvAEkttLYDMDIDITQKYVAVACQDRNVRVYN 656 555331144567777888999**99999******97 PP == domain 10 score: 9.5 bits; conditional E-value: 0.11 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriW 37 ++G ++ + ++p+g++la+++ D+++ + sp|O43379|WDR62_HUMAN 666 YKGSqGDegsLLKVHVDPSGTFLATSCSDKSISVI 700 5555433455567778*******96644****885 PP == domain 11 score: 11.6 bits; conditional E-value: 0.025 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+c+ + GHs +ts++f d + l++ s D v iW sp|O43379|WDR62_HUMAN 705 GECIAKMFGHSEiITSMKFTYDCHHLITVSGDSCVFIW 742 57888888**6657***********998766******* PP >> sp|O43379-4|WDR62_HUMAN Isoform 4 of WD repeat-containing protein 62 OS=Homo sapiens GN=WDR62 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.0 0.0003 0.024 2 38 .] 102 141 .. 101 141 .. 0.90 2 ? 11.1 0.0 0.036 2.9 6 38 .] 150 185 .. 145 185 .. 0.80 3 ? 8.6 0.1 0.22 18 13 37 .. 201 224 .. 192 224 .. 0.88 4 ? 4.8 0.0 3.4 2.8e+02 15 37 .. 302 320 .. 292 321 .. 0.75 5 ! 13.2 0.1 0.0076 0.62 15 38 .] 364 387 .. 348 387 .. 0.84 6 ! 14.6 0.0 0.0029 0.23 18 38 .] 422 441 .. 399 441 .. 0.74 7 ? 7.7 0.0 0.41 33 16 36 .. 498 518 .. 474 520 .. 0.83 8 ? 9.7 0.0 0.1 8.4 4 35 .. 573 606 .. 570 607 .. 0.83 9 ? 4.7 0.0 3.9 3.1e+02 8 38 .] 621 656 .. 615 656 .. 0.72 10 ? 9.5 0.1 0.12 9.3 7 37 .. 666 700 .. 660 701 .. 0.68 11 ? 11.6 0.7 0.025 2 1 37 [. 705 742 .. 705 743 .. 0.85 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 0.0003 EEEEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++++++ + +s ++lafspdg+++++G + + vriWd sp|O43379-4|WDR62_HUMAN 102 KQQHIFNTArKSLSALAFSPDGKYIVTGenGHRPAVRIWD 141 678999988899***************98866*******9 PP == domain 2 score: 11.1 bits; conditional E-value: 0.036 EEESSSS.EEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlas.G..sdDgtvriWd 38 + GH+ v ++afsp+ + ++s G + D + +Wd sp|O43379-4|WDR62_HUMAN 150 EMLGHKYgVACVAFSPNMKHIVSmGyqH-DMVLNVWD 185 5569*555************99656444.*******9 PP == domain 3 score: 8.6 bits; conditional E-value: 0.22 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 v +l+fs d++++++ + +++vr+W sp|O43379-4|WDR62_HUMAN 201 VIALSFSEDSSYFVTVG-NRHVRFW 224 45899**********9*.******* PP == domain 4 score: 4.8 bits; conditional E-value: 3.4 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ ++ ++++G+ Dg vri+ sp|O43379-4|WDR62_HUMAN 302 CV----SQELIFCGCTDGIVRIF 320 33....5566779999*****97 PP == domain 5 score: 13.2 bits; conditional E-value: 0.0076 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +l f+p ++wl++ +D++++iWd sp|O43379-4|WDR62_HUMAN 364 ALTFDPIHQWLSCVYKDHSIYIWD 387 788*******976699*******9 PP == domain 6 score: 14.6 bits; conditional E-value: 0.0029 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 p+g++l+++s D+t+r+W+ sp|O43379-4|WDR62_HUMAN 422 CLPSGSFLTCSS-DNTIRFWN 441 679****98777.*******8 PP == domain 7 score: 7.7 bits; conditional E-value: 0.41 EEEETTSSEEEEEETTSEEEE CS WD40 16 lafspdgawlasGsdDgtvri 36 +++spdg+ lasG++ g++ri sp|O43379-4|WDR62_HUMAN 498 MQVSPDGQHLASGDRSGNLRI 518 458**********99**9998 PP == domain 8 score: 9.7 bits; conditional E-value: 0.1 EEEEESS.SSEEEEEEETTSSE.EEEEETTSEEE CS WD40 4 lrtltGH.ssvtslafspdgaw.lasGsdDgtvr 35 +tl+ H ss+t+++f + + ++s++ D++++ sp|O43379-4|WDR62_HUMAN 573 EQTLDDHsSSITAIKFAGNRDIqMISCGADKSIY 606 679999*888****999999999667777***96 PP == domain 9 score: 4.7 bits; conditional E-value: 3.9 ESS..SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ss...vtslafspdgawlasGsdDgtvriWd 38 ++H ++++ + ++++a ++ D++vr+++ sp|O43379-4|WDR62_HUMAN 621 RTHhvAEkttLYDMDIDITQKYVAVACQDRNVRVYN 656 555331144567777888999**99999******97 PP == domain 10 score: 9.5 bits; conditional E-value: 0.12 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriW 37 ++G ++ + ++p+g++la+++ D+++ + sp|O43379-4|WDR62_HUMAN 666 YKGSqGDegsLLKVHVDPSGTFLATSCSDKSISVI 700 5555433455567778*******96644****885 PP == domain 11 score: 11.6 bits; conditional E-value: 0.025 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+c+ + GHs +ts++f d + l++ s D v iW sp|O43379-4|WDR62_HUMAN 705 GECIAKMFGHSEiITSMKFTYDCHHLITVSGDSCVFIW 742 57888888**6657***********998766******* PP >> sp|Q8N1V2|WDR16_HUMAN WD repeat-containing protein 16 OS=Homo sapiens GN=WDR16 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 0.00098 0.08 4 38 .] 57 97 .. 54 97 .. 0.76 2 ! 17.1 0.0 0.00046 0.037 5 38 .] 105 141 .. 101 141 .. 0.82 3 ? 5.0 0.0 3.1 2.5e+02 25 37 .. 174 185 .. 159 186 .. 0.79 4 ? 6.3 0.0 1.2 96 8 37 .. 329 359 .. 298 360 .. 0.80 5 ? 10.2 0.0 0.07 5.7 9 37 .. 415 444 .. 406 445 .. 0.83 6 ! 16.4 0.0 0.00077 0.062 7 38 .] 457 489 .. 451 489 .. 0.90 7 ! 16.9 0.1 0.00054 0.044 4 38 .] 537 573 .. 534 573 .. 0.86 8 ! 15.7 0.1 0.0012 0.099 3 37 .. 579 614 .. 577 615 .. 0.85 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 0.00098 EEEEESS.SSEEEEEEETTSSEEEEE.....ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.....sdDgtvriWd 38 + l GH ++v++la s++g ++asG + + + +Wd sp|Q8N1V2|WDR16_HUMAN 57 QNFLQGHgNNVSCLAISRSGEYIASGqvtfmGFKADIILWD 97 56689**999**************97543332377777776 PP == domain 2 score: 17.1 bits; conditional E-value: 0.00046 EEEESSSS.EEEEEEETTSSEEEE.EE.TTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlas.Gs.dDgtvriWd 38 l+ H++ + +lafsp+ +l+s G+ dDg+v +W+ sp|Q8N1V2|WDR16_HUMAN 105 ARLSLHKGkIEALAFSPNDLYLVSlGGpDDGSVVVWS 141 556679555*************9877788*******5 PP == domain 3 score: 5.0 bits; conditional E-value: 3.1 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 +++++ +gt+r+W sp|Q8N1V2|WDR16_HUMAN 174 FMTAG-NGTIRVW 185 45899.******* PP == domain 4 score: 6.3 bits; conditional E-value: 1.2 ESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGsdDgtvriW 37 t H + v ++ f+ a l a++ ++ +r+W sp|Q8N1V2|WDR16_HUMAN 329 TCHfDAVEDIVFPFGTAELfATCA-KKDIRVW 359 578555999987777777625667.******* PP == domain 5 score: 10.2 bits; conditional E-value: 0.07 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +vt++a+ +d + ++sG+ g vr+W sp|Q8N1V2|WDR16_HUMAN 415 AHrIGVTAIATTSDCKRVISGGGEGEVRVW 444 674349****999999999*988******* PP == domain 6 score: 16.4 bits; conditional E-value: 0.00077 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+ H ssv+++++ +++ +++s Dgt+ iWd sp|Q8N1V2|WDR16_HUMAN 457 LKEHkSSVSCIRVKRNNEECVTASTDGTCIIWD 489 789*888************999999*******9 PP == domain 7 score: 16.9 bits; conditional E-value: 0.00054 EEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 +r+l+G s+ +++++ ++g +++G+ D+ v++Wd sp|Q8N1V2|WDR16_HUMAN 537 IRELEGSlSGsINGMDITQEGVHFVTGGNDHLVKVWD 573 67788888444*************************9 PP == domain 8 score: 15.7 bits; conditional E-value: 0.0012 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++ GH +++t ++ sp +++++s s Dg + W sp|Q8N1V2|WDR16_HUMAN 579 VTHVGVGHsGNITRIRISPGNQYIVSVSADGAILRW 614 577888**655**************9999**99777 PP >> sp|Q05048|CSTF1_HUMAN Cleavage stimulation factor subunit 1 OS=Homo sapiens GN=CSTF1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.9 0.0 0.01 0.81 8 36 .. 105 134 .. 98 136 .. 0.82 2 ! 28.3 0.0 1.3e-07 1e-05 4 38 .] 166 201 .. 164 201 .. 0.94 3 ? 10.8 0.0 0.044 3.5 14 38 .] 221 245 .. 213 245 .. 0.93 4 ! 19.0 0.3 0.00011 0.0093 9 38 .] 260 290 .. 249 290 .. 0.83 5 ! 19.0 0.0 0.00012 0.0095 2 37 .. 295 333 .. 294 334 .. 0.87 6 ! 15.5 0.0 0.0015 0.12 3 37 .. 390 424 .. 388 424 .. 0.86 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.01 ESSSSEEEEE.EETTSSEEEEEETTSEEEE CS WD40 8 tGHssvtsla.fspdgawlasGsdDgtvri 36 t H++ + +a +s+dg+++a+Gs D +++i sp|Q05048|CSTF1_HUMAN 105 TSHKGPCRVAtYSRDGQLIATGSADASIKI 134 467555677789*****************9 PP == domain 2 score: 28.3 bits; conditional E-value: 1.3e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +rtl H + vt+laf+p + lasGs+D t++++d sp|Q05048|CSTF1_HUMAN 166 IRTLYDHvDEVTCLAFHPTEQILASGSRDYTLKLFD 201 689999*888************************98 PP == domain 3 score: 10.8 bits; conditional E-value: 0.044 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 +s++f+p+g++++ G+ +t+r++d sp|Q05048|CSTF1_HUMAN 221 RSISFHPSGDFILVGTQHPTLRLYD 245 699********************98 PP == domain 4 score: 19.0 bits; conditional E-value: 0.00011 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H + ++s+ ++++ ++ ++Gs+Dg +++Wd sp|Q05048|CSTF1_HUMAN 260 QHtDAICSVNYNSSANMYVTGSKDGCIKLWD 290 68555*****9999999889**********9 PP == domain 5 score: 19.0 bits; conditional E-value: 0.00012 EEEEEEE.SSSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtlt.GHss..vtslafspdgawlasGsdDgtvriW 37 +c++t++ +H++ v+s fs+++++++s+++D ++W sp|Q05048|CSTF1_HUMAN 295 RCITTFEkAHDGaeVCSAIFSKNSKYILSSGKDSVAKLW 333 69999955**3358*9999******************** PP == domain 6 score: 15.5 bits; conditional E-value: 0.0015 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l +l GH + v+++ sp ++ ++++sdD r+W sp|Q05048|CSTF1_HUMAN 390 NLLSL-GHnNIVRCIVHSPTNPGFMTCSDDFRARFW 424 55566.9*4558***********************9 PP >> sp|Q6IA86-3|ELP2_HUMAN Isoform 3 of Elongator complex protein 2 OS=Homo sapiens GN=ELP2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.3 0.009 0.73 4 37 .. 51 90 .. 48 91 .. 0.71 2 ? 8.3 0.0 0.27 22 6 38 .] 102 143 .. 98 143 .. 0.69 3 ! 18.5 0.3 0.00016 0.013 2 38 .] 172 211 .. 171 211 .. 0.85 4 ? 10.9 0.0 0.041 3.3 5 37 .. 251 293 .. 248 293 .. 0.80 5 ! 16.2 0.0 0.00087 0.071 4 36 .. 355 388 .. 352 390 .. 0.84 6 ? 5.2 0.0 2.7 2.2e+02 4 29 .. 534 560 .. 531 574 .. 0.83 7 ! 16.7 0.0 0.00062 0.05 2 38 .] 579 616 .. 578 616 .. 0.86 8 ! 23.8 1.8 3.6e-06 0.00029 7 37 .. 639 670 .. 634 670 .. 0.88 9 ? 5.7 0.0 1.8 1.4e+02 24 36 .. 778 792 .. 743 794 .. 0.83 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.009 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 ++ l GH v++++ sp+ ++ sG+ D+ v W sp|Q6IA86-3|ELP2_HUMAN 51 VTNLNGHtARVNCIQwickqdGSPSTELV-SGGSDNQVIHW 90 56789**6669999555555566666665.6766**99988 PP == domain 2 score: 8.3 bits; conditional E-value: 0.27 EEESS.SSEEEEE.......EETTSSE...EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgaw...lasGsdDgtvriWd 38 +l GH ++v+++ +p + ++s+ D vr+W+ sp|Q6IA86-3|ELP2_HUMAN 102 HLQGHeGPVYAVHavyqrrtSDPA--LctlIVSAAADSAVRLWS 143 789**8888888655566443333..2555567777*******5 PP == domain 3 score: 18.5 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 q++ +l GH ++++++ w las+s D+ +riW+ sp|Q6IA86-3|ELP2_HUMAN 172 QKVLSLCGHeDWIRGV------EWaafgrdlfLASCSQDCLIRIWK 211 6677889**888****......887777778889***********6 PP == domain 4 score: 10.9 bits; conditional E-value: 0.041 EEEESS.SSEEEEE....EETTSSE.....EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla....fspdgaw.....lasGsdDgtvriW 37 ++l GH ++v+++ f +dg + l+s+s+D+t +W sp|Q6IA86-3|ELP2_HUMAN 251 TVLAGHeNWVNAVHwqpvFYKDGVLqqpvrLLSASMDKTMILW 293 5688**999****555555555555*****889999****999 PP == domain 5 score: 16.2 bits; conditional E-value: 0.00087 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++GH ++v +l ++p+g ++++ + D+t r+ sp|Q6IA86-3|ELP2_HUMAN 355 EIVISGHfDGVQDLVWDPEGEFIITVGTDQTTRL 388 56789**777************997666***998 PP == domain 6 score: 5.2 bits; conditional E-value: 2.7 EEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGs 29 +++l GH+ + ++ ++++++las++ sp|Q6IA86-3|ELP2_HUMAN 534 VQKLYGHGYeIFCVTCNSSKTLLASAC 560 67889**446*************9886 PP == domain 7 score: 16.7 bits; conditional E-value: 0.00062 EEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 ++++ l H s vt +afsp+ ++l++ s+D+t +W+ sp|Q6IA86-3|ELP2_HUMAN 579 KQVQNLVFH-SltVTQMAFSPNEKFLLAVSRDRTWSLWK 616 667778889.446**************99*********6 PP == domain 8 score: 23.8 bits; conditional E-value: 3.6e-06 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 + Hs ++s+++spd++++++Gs+D++v +W sp|Q6IA86-3|ELP2_HUMAN 639 TSVHSRiIWSCDWSPDSKYFFTGSRDKKVVVW 670 46796667************************ PP == domain 9 score: 5.7 bits; conditional E-value: 1.8 E..EEEEETTSEEEE CS WD40 24 w..lasGsdDgtvri 36 w +as+++D+tv+i sp|Q6IA86-3|ELP2_HUMAN 778 WlhFASCGEDHTVKI 792 5335999*******9 PP >> tr|Q96Q25|Q96Q25_HUMAN KM-PA-2 protein OS=Homo sapiens GN=KM-PA-2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.8 0.2 1.5e-11 1.2e-09 6 37 .. 296 328 .. 291 329 .. 0.93 2 ? 5.0 0.0 3.1 2.5e+02 9 26 .. 420 438 .. 413 447 .. 0.83 3 ? 10.0 0.0 0.077 6.3 8 37 .. 465 493 .. 457 494 .. 0.86 4 ? 8.7 0.1 0.21 17 11 34 .. 509 532 .. 499 536 .. 0.86 5 ! 18.9 0.0 0.00013 0.01 3 35 .. 543 576 .. 541 577 .. 0.89 6 ! 24.4 0.0 2.3e-06 0.00018 3 37 .. 594 633 .. 592 634 .] 0.88 Alignments for each domain: == domain 1 score: 40.8 bits; conditional E-value: 1.5e-11 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriW 37 +++GHs+ v++l++sp g+wl+sGsdDg++r+W tr|Q96Q25|Q96Q25_HUMAN 296 VYRGHSDlVRCLSVSPGGQWLVSGSDDGSLRLW 328 69***8889************************ PP == domain 2 score: 5.0 bits; conditional E-value: 3.1 SS.SSEEEEEEETTSSEEE CS WD40 9 GH.ssvtslafspdgawla 26 H ++vt + ++ g++la tr|Q96Q25|Q96Q25_HUMAN 420 CHgKPVTQVTWHGRGDYLA 438 79899************87 PP == domain 3 score: 10.0 bits; conditional E-value: 0.077 ESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriW 37 + H+ v +af+p ++l+ +s ++vr++ tr|Q96Q25|Q96Q25_HUMAN 465 RSHGQVQRVAFHPARPFLLVAS-QRSVRLY 493 37877**************9**.*****98 PP == domain 4 score: 8.7 bits; conditional E-value: 0.21 SSEEEEEEETTSSEEEEEETTSEE CS WD40 11 ssvtslafspdgawlasGsdDgtv 34 ++v+sla++p g+ +++Gs+D ++ tr|Q96Q25|Q96Q25_HUMAN 509 KWVSSLAVHPAGDNVICGSYDSKL 532 569****************99987 PP == domain 5 score: 18.9 bits; conditional E-value: 0.00013 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvr 35 + r l+ H + +++af+p +++asGsdDg+v tr|Q96Q25|Q96Q25_HUMAN 543 PYRMLRHHkKALRAVAFHPRYPLFASGSDDGSVI 576 56788999888*********************96 PP == domain 6 score: 24.4 bits; conditional E-value: 2.3e-06 EEEEEESS..SS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH..ss...vtslafspdgawlasGsdDgtvriW 37 ++++l+GH + v ++ f+p ++w++s++ Dgtvr++ tr|Q96Q25|Q96Q25_HUMAN 594 PVKVLKGHvlTRdlgVLDVIFHPTQPWVFSSGADGTVRLF 633 7899****975579999***********99888*****96 PP >> sp|Q14137|BOP1_HUMAN Ribosome biogenesis protein BOP1 OS=Homo sapiens GN=BOP1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.5 0.2 1.9e-11 1.5e-09 6 37 .. 408 440 .. 403 441 .. 0.93 2 ? 4.7 0.0 3.8 3.1e+02 9 26 .. 532 550 .. 525 559 .. 0.84 3 ? 9.8 0.0 0.094 7.6 8 37 .. 577 605 .. 569 606 .. 0.86 4 ? 8.4 0.1 0.25 20 11 34 .. 621 644 .. 611 648 .. 0.86 5 ! 18.6 0.0 0.00016 0.013 3 35 .. 655 688 .. 653 689 .. 0.89 6 ! 24.1 0.0 2.8e-06 0.00022 3 37 .. 706 745 .. 704 746 .] 0.88 Alignments for each domain: == domain 1 score: 40.5 bits; conditional E-value: 1.9e-11 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriW 37 +++GHs+ v++l++sp g+wl+sGsdDg++r+W sp|Q14137|BOP1_HUMAN 408 VYRGHSDlVRCLSVSPGGQWLVSGSDDGSLRLW 440 69***8889************************ PP == domain 2 score: 4.7 bits; conditional E-value: 3.8 SS.SSEEEEEEETTSSEEE CS WD40 9 GH.ssvtslafspdgawla 26 H ++vt + ++ g++la sp|Q14137|BOP1_HUMAN 532 CHgKPVTQVTWHGRGDYLA 550 79899************87 PP == domain 3 score: 9.8 bits; conditional E-value: 0.094 ESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriW 37 + H+ v +af+p ++l+ +s ++vr++ sp|Q14137|BOP1_HUMAN 577 RSHGQVQRVAFHPARPFLLVAS-QRSVRLY 605 37877**************9**.*****98 PP == domain 4 score: 8.4 bits; conditional E-value: 0.25 SSEEEEEEETTSSEEEEEETTSEE CS WD40 11 ssvtslafspdgawlasGsdDgtv 34 ++v+sla++p g+ +++Gs+D ++ sp|Q14137|BOP1_HUMAN 621 KWVSSLAVHPAGDNVICGSYDSKL 644 569****************99887 PP == domain 5 score: 18.6 bits; conditional E-value: 0.00016 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvr 35 + r l+ H + +++af+p +++asGsdDg+v sp|Q14137|BOP1_HUMAN 655 PYRMLRHHkKALRAVAFHPRYPLFASGSDDGSVI 688 56788999888*********************96 PP == domain 6 score: 24.1 bits; conditional E-value: 2.8e-06 EEEEEESS..SS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH..ss...vtslafspdgawlasGsdDgtvriW 37 ++++l+GH + v ++ f+p ++w++s++ Dgtvr++ sp|Q14137|BOP1_HUMAN 706 PVKVLKGHvlTRdlgVLDVIFHPTQPWVFSSGADGTVRLF 745 7899****975579999***********99888*****96 PP >> sp|Q6IA86-5|ELP2_HUMAN Isoform 5 of Elongator complex protein 2 OS=Homo sapiens GN=ELP2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.3 0.0093 0.75 4 37 .. 51 90 .. 48 91 .. 0.71 2 ? 8.3 0.0 0.28 23 6 38 .] 102 143 .. 98 143 .. 0.69 3 ! 18.5 0.3 0.00017 0.014 2 38 .] 237 276 .. 236 276 .. 0.85 4 ? 10.9 0.0 0.042 3.4 5 37 .. 316 358 .. 313 358 .. 0.80 5 ! 16.2 0.0 0.0009 0.073 4 36 .. 376 409 .. 373 411 .. 0.84 6 ? 5.1 0.0 2.8 2.3e+02 4 29 .. 555 581 .. 552 595 .. 0.83 7 ! 16.6 0.0 0.00064 0.052 2 38 .] 600 637 .. 599 637 .. 0.86 8 ! 23.7 1.8 3.7e-06 0.0003 7 37 .. 660 691 .. 655 691 .. 0.88 9 ? 5.7 0.0 1.8 1.5e+02 24 36 .. 799 813 .. 764 815 .. 0.83 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0093 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 ++ l GH v++++ sp+ ++ sG+ D+ v W sp|Q6IA86-5|ELP2_HUMAN 51 VTNLNGHtARVNCIQwickqdGSPSTELV-SGGSDNQVIHW 90 56789**6669999555555566666665.6766**99988 PP == domain 2 score: 8.3 bits; conditional E-value: 0.28 EEESS.SSEEEEE.......EETTSSE...EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgaw...lasGsdDgtvriWd 38 +l GH ++v+++ +p + ++s+ D vr+W+ sp|Q6IA86-5|ELP2_HUMAN 102 HLQGHeGPVYAVHavyqrrtSDPA--LctlIVSAAADSAVRLWS 143 789**8888888655566443333..2555567777*******5 PP == domain 3 score: 18.5 bits; conditional E-value: 0.00017 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 q++ +l GH ++++++ w las+s D+ +riW+ sp|Q6IA86-5|ELP2_HUMAN 237 QKVLSLCGHeDWIRGV------EWaafgrdlfLASCSQDCLIRIWK 276 6677889**888****......887777778889***********6 PP == domain 4 score: 10.9 bits; conditional E-value: 0.042 EEEESS.SSEEEEE....EETTSSE.....EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla....fspdgaw.....lasGsdDgtvriW 37 ++l GH ++v+++ f +dg + l+s+s+D+t +W sp|Q6IA86-5|ELP2_HUMAN 316 TVLAGHeNWVNAVHwqpvFYKDGVLqqpvrLLSASMDKTMILW 358 5688**999****555555555555*****889999****999 PP == domain 5 score: 16.2 bits; conditional E-value: 0.0009 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++GH ++v +l ++p+g ++++ + D+t r+ sp|Q6IA86-5|ELP2_HUMAN 376 EIVISGHfDGVQDLVWDPEGEFIITVGTDQTTRL 409 56789**777************997666***998 PP == domain 6 score: 5.1 bits; conditional E-value: 2.8 EEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGs 29 +++l GH+ + ++ ++++++las++ sp|Q6IA86-5|ELP2_HUMAN 555 VQKLYGHGYeIFCVTCNSSKTLLASAC 581 67889**446*************9886 PP == domain 7 score: 16.6 bits; conditional E-value: 0.00064 EEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 ++++ l H s vt +afsp+ ++l++ s+D+t +W+ sp|Q6IA86-5|ELP2_HUMAN 600 KQVQNLVFH-SltVTQMAFSPNEKFLLAVSRDRTWSLWK 637 667778889.446**************99*********6 PP == domain 8 score: 23.7 bits; conditional E-value: 3.7e-06 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 + Hs ++s+++spd++++++Gs+D++v +W sp|Q6IA86-5|ELP2_HUMAN 660 TSVHSRiIWSCDWSPDSKYFFTGSRDKKVVVW 691 46796667************************ PP == domain 9 score: 5.7 bits; conditional E-value: 1.8 E..EEEEETTSEEEE CS WD40 24 w..lasGsdDgtvri 36 w +as+++D+tv+i sp|Q6IA86-5|ELP2_HUMAN 799 WlhFASCGEDHTVKI 813 5335999*******9 PP >> tr|H0YHT2|H0YHT2_HUMAN Kinesin-like protein KIF21A (Fragment) OS=Homo sapiens GN=KIF21A PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.3 4e-07 3.2e-05 2 38 .] 639 674 .. 638 674 .. 0.95 2 ? 11.5 0.1 0.026 2.1 1 38 [] 678 715 .. 678 715 .. 0.95 3 ? 10.9 0.0 0.043 3.5 5 38 .] 747 779 .. 743 779 .. 0.88 4 ! 19.4 0.0 8.8e-05 0.0071 2 38 .] 784 824 .. 783 824 .. 0.93 5 ? 5.7 0.0 1.8 1.4e+02 9 38 .] 842 870 .. 833 870 .. 0.71 6 ! 14.0 0.1 0.0043 0.35 4 38 .] 878 913 .. 876 913 .. 0.90 7 ! 22.5 0.0 9.1e-06 0.00074 3 38 .] 919 953 .. 917 953 .. 0.79 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 4e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+++ +GH + v ++ ++ ++l++Gs+D+t+++W+ tr|H0YHT2|H0YHT2_HUMAN 639 QCIHIAEGHtKAVLCV--DSTDDLLFTGSKDRTCKVWN 674 8********999****..99999999***********8 PP == domain 2 score: 11.5 bits; conditional E-value: 0.026 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq + +l GH ++v s++++ + +++++ s +++Wd tr|H0YHT2|H0YHT2_HUMAN 678 GQEIMSLGGHpNNVVSVKYCNYTSLVFTVS-TSYIKVWD 715 678999****99999***************.*******9 PP == domain 3 score: 10.9 bits; conditional E-value: 0.043 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 + +G + ++ +a +p g++l ++s + vr+Wd tr|H0YHT2|H0YHT2_HUMAN 747 AIPSGENQINQIALNPTGTFLYAAS-GNAVRMWD 779 56677788*****************.*******9 PP == domain 4 score: 19.4 bits; conditional E-value: 8.8e-05 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 q +++ltGH ++v +l s+ ++++++Gs+D+ ++++d tr|H0YHT2|H0YHT2_HUMAN 784 QSTGKLTGHlGPVMCLTvdqISSGQDLIITGSKDHYIKMFD 824 567889********************************998 PP == domain 5 score: 5.7 bits; conditional E-value: 1.8 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l + d+ l+sGs+D+ ++ Wd tr|H0YHT2|H0YHT2_HUMAN 842 PHyDGIEALTIQGDN--LFSGSRDNGIKKWD 870 466668888555554..559**********9 PP == domain 6 score: 14.0 bits; conditional E-value: 0.0043 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +H ++v++l + pd++ l+sG++ g +++W+ tr|H0YHT2|H0YHT2_HUMAN 878 QQVPNAHkDWVCALGVVPDHPVLLSGCRGGILKVWN 913 567789*666*************************8 PP == domain 7 score: 22.5 bits; conditional E-value: 9.1e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +GH s+++++++ +++ ++++ dD+tvriW+ tr|H0YHT2|H0YHT2_HUMAN 919 PVGEMKGHdSPINAICV--NSTHIFTAADDRTVRIWK 953 678899**888998865..5555558888*******6 PP >> sp|Q6Q0C0-2|TRAF7_HUMAN Isoform 2 of E3 ubiquitin-protein ligase TRAF7 OS=Homo sapiens GN=TRAF7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.1 0.8 9.3e-10 7.5e-08 2 38 .] 311 348 .. 310 348 .. 0.95 2 ! 21.8 0.2 1.5e-05 0.0012 2 38 .] 354 389 .. 353 389 .. 0.78 3 ? 9.7 0.1 0.1 8.1 2 38 .] 394 428 .. 393 428 .. 0.80 4 ? 10.7 0.0 0.049 4 13 38 .] 451 469 .. 435 469 .. 0.72 5 ? 6.0 1.3 1.5 1.2e+02 2 38 .] 474 509 .. 473 509 .. 0.82 6 ! 23.7 0.0 3.7e-06 0.0003 2 38 .] 514 553 .. 513 553 .. 0.93 7 ! 14.0 0.0 0.0043 0.35 3 37 .. 559 592 .. 557 593 .. 0.85 Alignments for each domain: == domain 1 score: 35.1 bits; conditional E-value: 9.3e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c +t+ GH ++v++l++ + g++l+sGs D+t+++Wd sp|Q6Q0C0-2|TRAF7_HUMAN 311 KCKGTFVGHqGPVWCLCVYSMGDLLFSGSSDKTIKVWD 348 899******888****************99*******9 PP == domain 2 score: 21.8 bits; conditional E-value: 1.5e-05 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +c++tl+GH++ v +l+ g l sGs D+t+ +Wd sp|Q6Q0C0-2|TRAF7_HUMAN 354 KCQKTLEGHDGiVLALCI--QGCKLYSGSADCTIIVWD 389 8********665666644..5555669**********9 PP == domain 3 score: 9.7 bits; conditional E-value: 0.1 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q++ t+++H ++v+ l ++++ l+sGs + +++Wd sp|Q6Q0C0-2|TRAF7_HUMAN 394 QKVNTIRAHdNPVCTL--VSSHNVLFSGS-LKAIKVWD 428 678899***9999888..444455679**.*******9 PP == domain 4 score: 10.7 bits; conditional E-value: 0.049 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v ++ ++l sGs +t++iWd sp|Q6Q0C0-2|TRAF7_HUMAN 451 VAAQ------SYLYSGS-YQTIKIWD 469 3344......78999**.*******9 PP == domain 5 score: 6.0 bits; conditional E-value: 1.5 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+++l + +sv+s+ ++ +++G++ + +++Wd sp|Q6Q0C0-2|TRAF7_HUMAN 474 DCIHVLQTSgGSVYSI--AVTNHHIVCGTYENLIHVWD 509 6999999887779999..445566889*99*******9 PP == domain 6 score: 23.7 bits; conditional E-value: 3.7e-06 EEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 +++rtltGH + v++la pd++ ++s+s+D+++r+W+ sp|Q6Q0C0-2|TRAF7_HUMAN 514 EQVRTLTGHvGTVYALAviSTPDQTKVFSASYDRSLRVWS 553 579******999*999999********************5 PP == domain 7 score: 14.0 bits; conditional E-value: 0.0043 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++tl H +svt+la+s+ + sG D tv++W sp|Q6Q0C0-2|TRAF7_HUMAN 559 CTQTLLRHqGSVTALAVSRGRLF--SGAVDSTVKVW 592 77887789888****88888777..8*9******** PP >> sp|Q9C0J8|WDR33_HUMAN pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens GN=WDR33 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.1 0.019 1.5 5 37 .. 155 188 .. 151 189 .. 0.90 2 ! 28.5 0.0 1.1e-07 9.1e-06 2 38 .] 193 230 .. 192 230 .. 0.92 3 ! 19.5 0.1 8.2e-05 0.0066 5 32 .. 238 266 .. 234 268 .. 0.91 4 ! 17.7 0.0 0.0003 0.024 1 38 [] 278 316 .. 278 316 .. 0.94 5 ! 16.2 0.0 0.0009 0.073 3 37 .. 323 359 .. 321 360 .. 0.84 6 ! 17.0 0.5 0.00048 0.038 9 37 .. 373 402 .. 367 403 .. 0.91 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.019 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l +H s+v+++ +s++ w+++++ g v+ W sp|Q9C0J8|WDR33_HUMAN 155 TILQAHdSPVRAMTWSHNDMWMLTADHGGYVKYW 188 5789**888****************88*****99 PP == domain 2 score: 28.5 bits; conditional E-value: 1.1e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ + +H ++ +fsp + +a++sdDgtvriWd sp|Q9C0J8|WDR33_HUMAN 193 NNVKMFQAHkEAIREASFSPTDNKFATCSDDGTVRIWD 230 68899****655*************************9 PP == domain 3 score: 19.5 bits; conditional E-value: 8.2e-05 EEEESS.SSEEEEEEETTSSEEEEEETTS CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDg 32 r+l+GH +v +++++p + +++sGs+D sp|Q9C0J8|WDR33_HUMAN 238 RILRGHgADVKCVDWHPTKGLVVSGSKDS 266 89****888*****************995 PP == domain 4 score: 17.7 bits; conditional E-value: 0.0003 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq l tl +H + v ++ + +g+wl+++s+D+ ++++d sp|Q9C0J8|WDR33_HUMAN 278 GQSLATLHAHkNTVMEVKLNLNGNWLLTASRDHLCKLFD 316 68899*****888************************98 PP == domain 5 score: 16.2 bits; conditional E-value: 0.0009 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgtvriW 37 l++++GH + t++a++p + l asG+ Dg++ +W sp|Q9C0J8|WDR33_HUMAN 323 ELQVFRGHkKEATAVAWHPVHEGLfASGGSDGSLLFW 359 6899****888****888888887368877******* PP == domain 6 score: 17.0 bits; conditional E-value: 0.00048 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 +H + ++sla++p g+ l+sGs D+t ++W sp|Q9C0J8|WDR33_HUMAN 373 AHEGmIWSLAWHPLGHILCSGSNDHTSKFW 402 58456************************* PP >> sp|Q05BV3-4|EMAL5_HUMAN Isoform 4 of Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens GN=EML5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 0.0011 0.085 4 38 .] 54 91 .. 51 91 .. 0.90 2 ? 10.5 0.4 0.055 4.4 7 38 .] 104 136 .. 96 136 .. 0.77 3 ? 12.8 0.0 0.011 0.87 9 38 .] 235 263 .. 226 263 .. 0.67 4 ! 26.4 0.0 5.2e-07 4.2e-05 3 38 .] 316 353 .. 314 353 .. 0.86 5 ? 11.9 0.0 0.02 1.6 10 34 .. 403 432 .. 396 435 .. 0.85 6 ? 5.9 0.0 1.5 1.2e+02 2 25 .. 446 466 .. 442 469 .. 0.83 7 ? 4.5 0.4 4.2 3.4e+02 11 37 .. 519 545 .. 494 546 .. 0.76 8 ! 24.8 1.9 1.7e-06 0.00013 3 38 .] 555 592 .. 553 592 .. 0.87 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 0.0011 EEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++ ++GH +++ sla +p+ ++a+G ++ + + iWd sp|Q05BV3-4|EMAL5_HUMAN 54 QKFYRGHsDDIISLALHPERVLVATGqvGKEPYICIWD 91 6779***66688**************999********9 PP == domain 2 score: 10.5 bits; conditional E-value: 0.055 EESSSSEEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 7 ltGHssvtslafspdgawlas.G..sdDgtvriWd 38 +H ++ +laf+ dg+ l+s G s ++ v +Wd sp|Q05BV3-4|EMAL5_HUMAN 104 VHTH-GIACLAFDLDGQRLVSvGldS-KNAVCVWD 136 3356.7************99625645.*******9 PP == domain 3 score: 12.8 bits; conditional E-value: 0.011 SS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +H ++ s+ + +a+G++Dg +r+Wd sp|Q05BV3-4|EMAL5_HUMAN 235 AHaAGIFSM--N----AceegFATGGRDGCIRLWD 263 555556666..2....2234479***********9 PP == domain 4 score: 26.4 bits; conditional E-value: 5.2e-07 EEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 + + GH + ++la++p +++ ++GsdD++vriW+ sp|Q05BV3-4|EMAL5_HUMAN 316 PFLIMQGHcEGeLWALAVHPTKPLAVTGSDDRSVRIWS 353 566778**7336*************************5 PP == domain 5 score: 11.9 bits; conditional E-value: 0.02 S.SS....EEEEEEETTSSEEEEEETTSEE CS WD40 10 H.ss....vtslafspdgawlasGsdDgtv 34 H ++ ++ l++spdg++la G+ D +v sp|Q05BV3-4|EMAL5_HUMAN 403 HiKDrkeaIHELKYSPDGTYLAVGCNDSSV 432 66566667999*************999987 PP == domain 6 score: 5.9 bits; conditional E-value: 1.5 EEEEEEESSSSEEEEEEETTSSEE CS WD40 2 qclrtltGHssvtslafspdgawl 25 +cl++l+ ++t+l++s+d+++l sp|Q05BV3-4|EMAL5_HUMAN 446 ECLGSLS---FITHLDWSSDSRYL 466 5666666...8**********996 PP == domain 7 score: 4.5 bits; conditional E-value: 4.2 SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 11 ssvtslafspdgaw....lasGsdDgtvriW 37 ++++s+ dg++ l++++d g ++++ sp|Q05BV3-4|EMAL5_HUMAN 519 NDINSV----DGNYigqvLVTADDYGIIKLF 545 357777....5566555489**99****996 PP == domain 8 score: 24.8 bits; conditional E-value: 1.7e-06 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriWd 38 + r++ GH +vt +++s+d +w++s G+ D++v W+ sp|Q05BV3-4|EMAL5_HUMAN 555 KFRKYIGHsAHVTNVRWSHDYQWVISiGGADHSVFQWK 592 578999**777************9755888*******5 PP >> sp|A2RRH5|WDR27_HUMAN WD repeat-containing protein 27 OS=Homo sapiens GN=WDR27 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 1.3 1.1e+02 4 34 .. 64 97 .. 61 100 .. 0.66 2 ! 13.0 0.0 0.0092 0.75 6 38 .] 159 193 .. 154 193 .. 0.83 3 ? 12.4 0.1 0.014 1.1 13 38 .] 516 541 .. 507 541 .. 0.82 4 ! 32.8 0.3 5.1e-09 4.2e-07 6 38 .] 550 583 .. 547 583 .. 0.92 5 ! 19.3 0.0 9.2e-05 0.0075 2 37 .. 744 782 .. 743 783 .. 0.88 6 ! 15.7 0.0 0.0013 0.1 5 36 .. 791 823 .. 787 824 .. 0.86 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 1.3 EEEEESS.SSEEEEE.EETTSSEEE.EEETTSEE CS WD40 4 lrtltGH.ssvtsla.fspdgawla.sGsdDgtv 34 l +l+GH +++t++a ++ +++l+ s+s D + sp|A2RRH5|WDR27_HUMAN 64 LLILRGHhQPITAMAfGNKVNPLLIcSASLDYVI 97 6789***999****76444444454144656555 PP == domain 2 score: 13.0 bits; conditional E-value: 0.0092 EEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 +l GH ++vt++ + l+s+s+D+ ++Wd sp|A2RRH5|WDR27_HUMAN 159 ELQGHlGPVTAVE------FcpwragtLISASEDRGFKVWD 193 689*********6......44446669899**********9 PP == domain 3 score: 12.4 bits; conditional E-value: 0.014 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v+++++s dg+wla+G ++ + ++d sp|A2RRH5|WDR27_HUMAN 516 VCCIQYSGDGQWLACGLANHLLLVFD 541 9*************995588877776 PP == domain 4 score: 32.8 bits; conditional E-value: 5.1e-09 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH + v+++++s+d +wl+s+ +Dgt+r+W+ sp|A2RRH5|WDR27_HUMAN 550 VFSGHdGAVNAVCWSQDRRWLLSAARDGTLRMWS 583 799**666****************9********5 PP == domain 5 score: 19.3 bits; conditional E-value: 9.2e-05 EEEEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ss..vtslafspdgawlasGsdDgtvriW 37 +c r+++GH + +++afsp g++ a+G +D++ +++ sp|A2RRH5|WDR27_HUMAN 744 RCERHFEGHpTRgyPCGIAFSPCGRFAACGAEDRHAYVY 782 699******7446789***********9999****9887 PP == domain 6 score: 15.7 bits; conditional E-value: 0.0013 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvri 36 + l GH + vt++af+p+ + la+++ Dg++ + sp|A2RRH5|WDR27_HUMAN 791 HRLAGHtDTVTGVAFNPSAPQLATATLDGKLQL 823 6688**666****************99*99865 PP >> tr|F2Z2U5|F2Z2U5_HUMAN WD repeat-containing protein 27 OS=Homo sapiens GN=WDR27 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 1.4 1.1e+02 4 34 .. 64 97 .. 61 100 .. 0.66 2 ! 13.0 0.0 0.0092 0.74 6 38 .] 189 223 .. 182 223 .. 0.83 3 ? 12.4 0.1 0.014 1.2 13 38 .] 546 571 .. 537 571 .. 0.82 4 ! 32.7 0.3 5.4e-09 4.3e-07 6 38 .] 580 613 .. 577 613 .. 0.92 5 ! 19.2 0.0 9.6e-05 0.0078 2 37 .. 774 812 .. 773 813 .. 0.88 6 ! 15.6 0.0 0.0013 0.11 5 36 .. 821 853 .. 817 854 .. 0.86 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 1.4 EEEEESS.SSEEEEE.EETTSSEEE.EEETTSEE CS WD40 4 lrtltGH.ssvtsla.fspdgawla.sGsdDgtv 34 l +l+GH +++t++a ++ +++l+ s+s D + tr|F2Z2U5|F2Z2U5_HUMAN 64 LLILRGHhQPITAMAfGNKVNPLLIcSASLDYVI 97 6789***999****76444444454144656555 PP == domain 2 score: 13.0 bits; conditional E-value: 0.0092 EEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 +l GH ++vt++ + l+s+s+D+ ++Wd tr|F2Z2U5|F2Z2U5_HUMAN 189 ELQGHlGPVTAVE------FcpwragtLISASEDRGFKVWD 223 689*********6......44446669899**********9 PP == domain 3 score: 12.4 bits; conditional E-value: 0.014 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v+++++s dg+wla+G ++ + ++d tr|F2Z2U5|F2Z2U5_HUMAN 546 VCCIQYSGDGQWLACGLANHLLLVFD 571 9*************995588877776 PP == domain 4 score: 32.7 bits; conditional E-value: 5.4e-09 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH + v+++++s+d +wl+s+ +Dgt+r+W+ tr|F2Z2U5|F2Z2U5_HUMAN 580 VFSGHdGAVNAVCWSQDRRWLLSAARDGTLRMWS 613 799**666****************9********5 PP == domain 5 score: 19.2 bits; conditional E-value: 9.6e-05 EEEEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ss..vtslafspdgawlasGsdDgtvriW 37 +c r+++GH + +++afsp g++ a+G +D++ +++ tr|F2Z2U5|F2Z2U5_HUMAN 774 RCERHFEGHpTRgyPCGIAFSPCGRFAACGAEDRHAYVY 812 699******7446789***********9999****9887 PP == domain 6 score: 15.6 bits; conditional E-value: 0.0013 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvri 36 + l GH + vt++af+p+ + la+++ Dg++ + tr|F2Z2U5|F2Z2U5_HUMAN 821 HRLAGHtDTVTGVAFNPSAPQLATATLDGKLQL 853 6688**666****************99*99865 PP >> sp|Q6IA86-6|ELP2_HUMAN Isoform 6 of Elongator complex protein 2 OS=Homo sapiens GN=ELP2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.3 0.01 0.83 4 37 .. 51 90 .. 48 91 .. 0.71 2 ? 8.1 0.0 0.31 25 6 38 .] 102 143 .. 98 143 .. 0.69 3 ! 18.3 0.3 0.00019 0.015 2 38 .] 263 302 .. 262 302 .. 0.85 4 ? 10.8 0.0 0.046 3.7 5 37 .. 342 384 .. 339 384 .. 0.80 5 ! 16.0 0.0 0.00099 0.08 4 36 .. 446 479 .. 443 481 .. 0.84 6 ? 5.0 0.0 3.1 2.5e+02 4 29 .. 625 651 .. 622 665 .. 0.83 7 ! 16.5 0.0 0.00071 0.057 2 38 .] 670 707 .. 669 707 .. 0.86 8 ! 23.6 1.8 4e-06 0.00033 7 37 .. 730 761 .. 725 761 .. 0.88 9 ? 5.6 0.0 2 1.6e+02 24 36 .. 869 883 .. 834 885 .. 0.83 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.01 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 ++ l GH v++++ sp+ ++ sG+ D+ v W sp|Q6IA86-6|ELP2_HUMAN 51 VTNLNGHtARVNCIQwickqdGSPSTELV-SGGSDNQVIHW 90 56789**6669999555555566666665.6766**99988 PP == domain 2 score: 8.1 bits; conditional E-value: 0.31 EEESS.SSEEEEE.......EETTSSE...EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgaw...lasGsdDgtvriWd 38 +l GH ++v+++ +p + ++s+ D vr+W+ sp|Q6IA86-6|ELP2_HUMAN 102 HLQGHeGPVYAVHavyqrrtSDPA--LctlIVSAAADSAVRLWS 143 7899*8888888655566443333..2555567777*******5 PP == domain 3 score: 18.3 bits; conditional E-value: 0.00019 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 q++ +l GH ++++++ w las+s D+ +riW+ sp|Q6IA86-6|ELP2_HUMAN 263 QKVLSLCGHeDWIRGV------EWaafgrdlfLASCSQDCLIRIWK 302 6677889**888****......887777778889***********6 PP == domain 4 score: 10.8 bits; conditional E-value: 0.046 EEEESS.SSEEEEE....EETTSSE.....EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla....fspdgaw.....lasGsdDgtvriW 37 ++l GH ++v+++ f +dg + l+s+s+D+t +W sp|Q6IA86-6|ELP2_HUMAN 342 TVLAGHeNWVNAVHwqpvFYKDGVLqqpvrLLSASMDKTMILW 384 5688**999****555555555555*****889999****999 PP == domain 5 score: 16.0 bits; conditional E-value: 0.00099 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++GH ++v +l ++p+g ++++ + D+t r+ sp|Q6IA86-6|ELP2_HUMAN 446 EIVISGHfDGVQDLVWDPEGEFIITVGTDQTTRL 479 56789**777************997666***998 PP == domain 6 score: 5.0 bits; conditional E-value: 3.1 EEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGs 29 +++l GH+ + ++ ++++++las++ sp|Q6IA86-6|ELP2_HUMAN 625 VQKLYGHGYeIFCVTCNSSKTLLASAC 651 67889**446*************9886 PP == domain 7 score: 16.5 bits; conditional E-value: 0.00071 EEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 ++++ l H s vt +afsp+ ++l++ s+D+t +W+ sp|Q6IA86-6|ELP2_HUMAN 670 KQVQNLVFH-SltVTQMAFSPNEKFLLAVSRDRTWSLWK 707 667778889.446**************99*********6 PP == domain 8 score: 23.6 bits; conditional E-value: 4e-06 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 + Hs ++s+++spd++++++Gs+D++v +W sp|Q6IA86-6|ELP2_HUMAN 730 TSVHSRiIWSCDWSPDSKYFFTGSRDKKVVVW 761 46796667************************ PP == domain 9 score: 5.6 bits; conditional E-value: 2 E..EEEEETTSEEEE CS WD40 24 w..lasGsdDgtvri 36 w +as+++D+tv+i sp|Q6IA86-6|ELP2_HUMAN 869 WlhFASCGEDHTVKI 883 5335999*******9 PP >> tr|H0YED0|H0YED0_HUMAN Kinesin-like protein KIF21B (Fragment) OS=Homo sapiens GN=KIF21B PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.0 3.7e-05 0.003 2 38 .] 418 453 .. 417 453 .. 0.92 2 ? 10.6 0.1 0.051 4.1 2 38 .] 458 494 .. 457 494 .. 0.92 3 ? 11.1 0.0 0.035 2.8 10 37 .. 532 557 .. 520 558 .. 0.87 4 ! 18.0 0.0 0.00024 0.02 2 37 .. 563 602 .. 562 603 .. 0.91 5 ? 8.7 0.0 0.21 17 9 38 .] 621 649 .. 611 649 .. 0.79 6 ! 13.6 0.0 0.0059 0.48 5 38 .] 658 692 .. 654 692 .. 0.89 7 ! 19.7 0.1 6.7e-05 0.0054 3 38 .] 698 732 .. 696 732 .. 0.80 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 3.7e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+ +GH +++ +l + +l++Gs+D+++++W+ tr|H0YED0|H0YED0_HUMAN 418 QCVSMAEGHtKPILCL--DATDELLFTGSKDRSCKMWN 453 6778889**999****..999999*************8 PP == domain 2 score: 10.6 bits; conditional E-value: 0.051 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q + l+GH ++v s+++++++ +++s s +++Wd tr|H0YED0|H0YED0_HUMAN 458 QEIAALKGHpNNVVSIKYCSHSGLVFSVS-TSYIKVWD 494 778889***99999**********9999*.*******9 PP == domain 3 score: 11.1 bits; conditional E-value: 0.035 SSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriW 37 H ++ +a sp+g++l ++s + vriW tr|H0YED0|H0YED0_HUMAN 532 H-QINQIALSPSGTMLYAAS-GNAVRIW 557 4.59****************.******* PP == domain 4 score: 18.0 bits; conditional E-value: 0.00024 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriW 37 q++++ltGH ++v +l + + ++++++Gs+D+ v+++ tr|H0YED0|H0YED0_HUMAN 563 QPVGKLTGHiGPVMCLTvtqTASQHDLVVTGSKDHYVKMF 602 899*************998888888889*********986 PP == domain 5 score: 8.7 bits; conditional E-value: 0.21 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l g+ l+sGs+D+ ++ Wd tr|H0YED0|H0YED0_HUMAN 621 PHyDGIECL--AIQGDILFSGSRDNGIKKWD 649 477779999..44788899***********9 PP == domain 6 score: 13.6 bits; conditional E-value: 0.0059 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +H ++v++laf p ++l+s+++ g +++W+ tr|H0YED0|H0YED0_HUMAN 658 QIPNAHkDWVCALAFIPGRPMLLSACRAGVIKVWN 692 66789*666*************************8 PP == domain 7 score: 19.7 bits; conditional E-value: 6.7e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++++GH s++++++++ + + +++s D+ v++W+ tr|H0YED0|H0YED0_HUMAN 698 PIGEIKGHdSPINAICTNAKHIF-TASS-DCRVKLWN 732 78899***888****77666666.4456.*******8 PP >> tr|E7ESC9|E7ESC9_HUMAN WD repeat-containing protein 17 OS=Homo sapiens GN=WDR17 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.2 0.0018 0.15 6 38 .] 78 112 .. 73 112 .. 0.82 2 ! 20.3 0.1 4.4e-05 0.0035 5 38 .] 371 405 .. 367 405 .. 0.84 3 ? 9.3 0.3 0.13 10 3 34 .. 454 488 .. 452 490 .. 0.77 4 ? 10.5 0.0 0.056 4.6 2 37 .. 496 532 .. 495 532 .. 0.79 5 ! 30.1 0.3 3.5e-08 2.8e-06 2 38 .] 540 578 .. 539 578 .. 0.83 6 ! 22.5 0.1 8.9e-06 0.00072 3 38 .] 584 621 .. 582 621 .. 0.85 7 ! 18.7 0.5 0.00014 0.011 1 38 [] 625 664 .. 625 664 .. 0.91 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.0018 EEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + + H + +t+++++p+++ l asGs D+ v iW+ tr|E7ESC9|E7ESC9_HUMAN 78 IMSEHkKTITAISWCPHNPDLfASGSTDNLVIIWN 112 4678*888****977777776379999*******8 PP == domain 2 score: 20.3 bits; conditional E-value: 4.4e-05 EEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 r l GH + +++f pd + l a++s Dgt+++Wd tr|E7ESC9|E7ESC9_HUMAN 371 RDL-GHvETIFDCKFKPDDPNLlATASFDGTIKVWD 405 555.9*888************7368899*******9 PP == domain 3 score: 9.3 bits; conditional E-value: 0.13 EEEEEESS..SSEEEEE.EETTSSEEEEEETTSEE CS WD40 3 clrtltGH..ssvtsla.fspdgawlasGsdDgtv 34 ++ + H +++ ++a ++d++ +a++s Dg + tr|E7ESC9|E7ESC9_HUMAN 454 IIQRFNEHgtNGIFCIAwSHKDSKRIATCSSDGFC 488 567788898777****977777777**9988*977 PP == domain 4 score: 10.5 bits; conditional E-value: 0.056 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 + l++++ H v ++++s++++ +a+G++D +vr++ tr|E7ESC9|E7ESC9_HUMAN 496 KVLHKYK-HpAAVFGCDWSQNNKDmIATGCEDTNVRVY 532 6789997.8677****96666555478*********97 PP == domain 5 score: 30.1 bits; conditional E-value: 3.5e-08 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 q+l++++GH v ++++sp l+sGsdDgtvriWd tr|E7ESC9|E7ESC9_HUMAN 540 QPLKVFSGHtAKVFHVKWSPLREGiLCSGSDDGTVRIWD 578 799******666****7666666655689*********9 PP == domain 6 score: 22.5 bits; conditional E-value: 8.9e-06 EEEEEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 c+ +l GH +v++l w l+sGs+D t+++Wd tr|E7ESC9|E7ESC9_HUMAN 584 CINILNGHtAPVRGL------MWnteipylLISGSWDYTIKVWD 621 8999****888****......66666666667***********9 PP == domain 7 score: 18.7 bits; conditional E-value: 0.00014 TEEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+ t H +v++l +p+ ++ +as+s+D tvr+W+ tr|E7ESC9|E7ESC9_HUMAN 625 GTCVDTVYDHgADVYGLTCHPSRPFtMASCSRDSTVRLWS 664 578999999*888************989***********5 PP >> sp|Q6Q0C0|TRAF7_HUMAN E3 ubiquitin-protein ligase TRAF7 OS=Homo sapiens GN=TRAF7 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.9 0.8 1.1e-09 8.7e-08 2 38 .] 387 424 .. 386 424 .. 0.95 2 ! 21.6 0.2 1.7e-05 0.0014 2 38 .] 430 465 .. 429 465 .. 0.78 3 ? 9.5 0.1 0.12 9.4 2 38 .] 470 504 .. 469 504 .. 0.80 4 ? 10.5 0.0 0.056 4.6 13 38 .] 527 545 .. 511 545 .. 0.72 5 ? 5.8 1.3 1.7 1.4e+02 2 38 .] 550 585 .. 549 585 .. 0.82 6 ! 23.5 0.0 4.3e-06 0.00035 2 38 .] 590 629 .. 589 629 .. 0.93 7 ! 13.8 0.0 0.005 0.41 3 37 .. 635 668 .. 633 669 .. 0.85 Alignments for each domain: == domain 1 score: 34.9 bits; conditional E-value: 1.1e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c +t+ GH ++v++l++ + g++l+sGs D+t+++Wd sp|Q6Q0C0|TRAF7_HUMAN 387 KCKGTFVGHqGPVWCLCVYSMGDLLFSGSSDKTIKVWD 424 899******888****************99*******9 PP == domain 2 score: 21.6 bits; conditional E-value: 1.7e-05 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +c++tl+GH++ v +l+ g l sGs D+t+ +Wd sp|Q6Q0C0|TRAF7_HUMAN 430 KCQKTLEGHDGiVLALCI--QGCKLYSGSADCTIIVWD 465 8********665666644..5555669**********9 PP == domain 3 score: 9.5 bits; conditional E-value: 0.12 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q++ t+++H ++v+ l ++++ l+sGs + +++Wd sp|Q6Q0C0|TRAF7_HUMAN 470 QKVNTIRAHdNPVCTL--VSSHNVLFSGS-LKAIKVWD 504 678899***9999888..444455679**.*******9 PP == domain 4 score: 10.5 bits; conditional E-value: 0.056 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v ++ ++l sGs +t++iWd sp|Q6Q0C0|TRAF7_HUMAN 527 VAAQ------SYLYSGS-YQTIKIWD 545 3344......78999**.*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+++l + +sv+s+ ++ +++G++ + +++Wd sp|Q6Q0C0|TRAF7_HUMAN 550 DCIHVLQTSgGSVYSI--AVTNHHIVCGTYENLIHVWD 585 6999999887779999..445566889*99*******9 PP == domain 6 score: 23.5 bits; conditional E-value: 4.3e-06 EEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 +++rtltGH + v++la pd++ ++s+s+D+++r+W+ sp|Q6Q0C0|TRAF7_HUMAN 590 EQVRTLTGHvGTVYALAviSTPDQTKVFSASYDRSLRVWS 629 579******999*999999********************5 PP == domain 7 score: 13.8 bits; conditional E-value: 0.005 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++tl H +svt+la+s+ + sG D tv++W sp|Q6Q0C0|TRAF7_HUMAN 635 CTQTLLRHqGSVTALAVSRGRLF--SGAVDSTVKVW 668 77887789888****88888777..8*9******** PP >> sp|Q8IZU2-2|WDR17_HUMAN Isoform 2 of WD repeat-containing protein 17 OS=Homo sapiens GN=WDR17 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.2 0.0018 0.15 6 38 .] 54 88 .. 49 88 .. 0.82 2 ! 20.3 0.1 4.3e-05 0.0035 5 38 .] 364 398 .. 360 398 .. 0.84 3 ? 9.4 0.3 0.13 10 3 34 .. 447 481 .. 445 483 .. 0.77 4 ? 10.5 0.0 0.056 4.5 2 37 .. 489 525 .. 488 525 .. 0.79 5 ! 30.2 0.3 3.4e-08 2.8e-06 2 38 .] 533 571 .. 532 571 .. 0.83 6 ! 22.5 0.1 8.8e-06 0.00071 3 38 .] 577 614 .. 575 614 .. 0.85 7 ! 18.8 0.5 0.00014 0.011 1 38 [] 618 657 .. 618 657 .. 0.91 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.0018 EEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + + H + +t+++++p+++ l asGs D+ v iW+ sp|Q8IZU2-2|WDR17_HUMAN 54 IMSEHkKTITAISWCPHNPDLfASGSTDNLVIIWN 88 4678*888****977777776379999*******8 PP == domain 2 score: 20.3 bits; conditional E-value: 4.3e-05 EEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 r l GH + +++f pd + l a++s Dgt+++Wd sp|Q8IZU2-2|WDR17_HUMAN 364 RDL-GHvETIFDCKFKPDDPNLlATASFDGTIKVWD 398 555.9*888************7368899*******9 PP == domain 3 score: 9.4 bits; conditional E-value: 0.13 EEEEEESS..SSEEEEE.EETTSSEEEEEETTSEE CS WD40 3 clrtltGH..ssvtsla.fspdgawlasGsdDgtv 34 ++ + H +++ ++a ++d++ +a++s Dg + sp|Q8IZU2-2|WDR17_HUMAN 447 IIQRFNEHgtNGIFCIAwSHKDSKRIATCSSDGFC 481 567788898777****977777777**9988*977 PP == domain 4 score: 10.5 bits; conditional E-value: 0.056 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 + l++++ H v ++++s++++ +a+G++D +vr++ sp|Q8IZU2-2|WDR17_HUMAN 489 KVLHKYK-HpAAVFGCDWSQNNKDmIATGCEDTNVRVY 525 6789997.8677****96666555478*********97 PP == domain 5 score: 30.2 bits; conditional E-value: 3.4e-08 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 q+l++++GH v ++++sp l+sGsdDgtvriWd sp|Q8IZU2-2|WDR17_HUMAN 533 QPLKVFSGHtAKVFHVKWSPLREGiLCSGSDDGTVRIWD 571 799******666****7666666655689*********9 PP == domain 6 score: 22.5 bits; conditional E-value: 8.8e-06 EEEEEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 c+ +l GH +v++l w l+sGs+D t+++Wd sp|Q8IZU2-2|WDR17_HUMAN 577 CINILNGHtAPVRGL------MWnteipylLISGSWDYTIKVWD 614 8999****888****......66666666667***********9 PP == domain 7 score: 18.8 bits; conditional E-value: 0.00014 TEEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+ t H +v++l +p+ ++ +as+s+D tvr+W+ sp|Q8IZU2-2|WDR17_HUMAN 618 GTCVDTVYDHgADVYGLTCHPSRPFtMASCSRDSTVRLWS 657 578999999*888************989***********5 PP >> sp|O60336-3|MABP1_HUMAN Isoform 3 of Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens GN=MAPKBP1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 0.00042 0.034 10 38 .] 84 120 .. 75 120 .. 0.73 2 ! 13.3 0.0 0.0071 0.58 4 37 .. 127 163 .. 125 163 .. 0.79 3 ! 13.1 0.1 0.0084 0.68 12 37 .. 178 203 .. 168 203 .. 0.90 4 ? 11.7 0.1 0.024 1.9 20 38 .] 287 304 .. 278 304 .. 0.80 5 ? 8.7 0.0 0.2 16 13 30 .. 359 376 .. 350 383 .. 0.83 6 ? 4.6 0.0 4.1 3.4e+02 7 36 .. 394 427 .. 386 429 .. 0.71 7 ? 10.6 0.0 0.051 4.1 3 36 .. 436 461 .. 434 472 .. 0.63 8 ? 7.9 0.0 0.36 29 15 38 .] 543 566 .. 525 566 .. 0.76 9 ! 16.8 0.3 0.00055 0.045 1 37 [. 570 607 .. 570 608 .. 0.88 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 0.00042 S..SS....EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 10 H..ss....vtslafspdgawlasG..sdDgtvriWd 38 H +s +t+lafspdg++l++G + + vr+Wd sp|O60336-3|MABP1_HUMAN 84 HilNSsrktITALAFSPDGKYLVTGesGHMPAVRVWD 120 455334666**************98654588888887 PP == domain 2 score: 13.3 bits; conditional E-value: 0.0071 EEEEESSSS.EEEEEEETTSSEEEEEET..TSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsd..DgtvriW 37 + +l H+ v ++afsp+ ++++s ++ D v +W sp|O60336-3|MABP1_HUMAN 127 VAELQEHKYgVACVAFSPSAKYIVSVGYqhDMIVNVW 163 5678889455************99755223**99999 PP == domain 3 score: 13.1 bits; conditional E-value: 0.0084 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 s vt+++fs d +++++++ ++++++W sp|O60336-3|MABP1_HUMAN 178 SrVTAVSFSEDCSYFVTAG-NRHIKFW 203 349****************.******* PP == domain 4 score: 11.7 bits; conditional E-value: 0.024 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 p +++++++s D+t+r+W+ sp|O60336-3|MABP1_HUMAN 287 PPSSFITCSS-DNTIRLWN 304 6778887666.*******8 PP == domain 5 score: 8.7 bits; conditional E-value: 0.2 EEEEEEETTSSEEEEEET CS WD40 13 vtslafspdgawlasGsd 30 ++s+++sp+g+ lasG++ sp|O60336-3|MABP1_HUMAN 359 IRSVCVSPNGQHLASGDR 376 89***********98864 PP == domain 6 score: 4.6 bits; conditional E-value: 4.1 EESS.SSEEEEE...EETTSSE...EEEEETTSEEEE CS WD40 7 ltGH.ssvtsla...fspdgaw...lasGsdDgtvri 36 ++H s + +l + las+s+D+ +++ sp|O60336-3|MABP1_HUMAN 394 VEAHdSEILCLEyskPDT---GlklLASASRDRLIHV 427 579966699997533333...24558999****9987 PP == domain 7 score: 10.6 bits; conditional E-value: 0.051 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++tl+ H ss+t+++ + ++s Dg vr+ sp|O60336-3|MABP1_HUMAN 436 LQQTLDEHsSSITAVK------F--AAS-DGQVRM 461 7899****888****4......4..344.444443 PP == domain 8 score: 7.9 bits; conditional E-value: 0.36 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++++p+g ++a+++ D+++ i+d sp|O60336-3|MABP1_HUMAN 543 KVQTDPSGIYIATSCSDKNLSIFD 566 6789*******96644*****998 PP == domain 9 score: 16.8 bits; conditional E-value: 0.00055 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+c+ t GHs vt+++fs d + l+s s D + +W sp|O60336-3|MABP1_HUMAN 570 GECVATMFGHSEiVTGMKFSNDCKHLISVSGDSCIFVW 607 68999999**6657************98766******* PP >> tr|C9JL14|C9JL14_HUMAN Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens GN=MAPKBP1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 0.00042 0.034 10 38 .] 84 120 .. 75 120 .. 0.73 2 ! 13.3 0.0 0.0071 0.58 4 37 .. 127 163 .. 125 163 .. 0.79 3 ! 13.1 0.1 0.0084 0.68 12 37 .. 178 203 .. 168 203 .. 0.90 4 ? 11.7 0.1 0.024 1.9 20 38 .] 287 304 .. 278 304 .. 0.80 5 ? 8.7 0.0 0.2 16 13 30 .. 359 376 .. 350 383 .. 0.83 6 ? 4.6 0.0 4.2 3.4e+02 7 36 .. 394 427 .. 386 429 .. 0.71 7 ? 10.6 0.0 0.051 4.1 3 36 .. 436 461 .. 434 472 .. 0.63 8 ? 7.9 0.0 0.36 29 15 38 .] 543 566 .. 525 566 .. 0.76 9 ! 16.8 0.3 0.00055 0.045 1 37 [. 570 607 .. 570 608 .. 0.88 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 0.00042 S..SS....EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 10 H..ss....vtslafspdgawlasG..sdDgtvriWd 38 H +s +t+lafspdg++l++G + + vr+Wd tr|C9JL14|C9JL14_HUMAN 84 HilNSsrktITALAFSPDGKYLVTGesGHMPAVRVWD 120 455334666**************98654588888887 PP == domain 2 score: 13.3 bits; conditional E-value: 0.0071 EEEEESSSS.EEEEEEETTSSEEEEEET..TSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsd..DgtvriW 37 + +l H+ v ++afsp+ ++++s ++ D v +W tr|C9JL14|C9JL14_HUMAN 127 VAELQEHKYgVACVAFSPSAKYIVSVGYqhDMIVNVW 163 5678889455************99755223**99999 PP == domain 3 score: 13.1 bits; conditional E-value: 0.0084 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 s vt+++fs d +++++++ ++++++W tr|C9JL14|C9JL14_HUMAN 178 SrVTAVSFSEDCSYFVTAG-NRHIKFW 203 349****************.******* PP == domain 4 score: 11.7 bits; conditional E-value: 0.024 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 p +++++++s D+t+r+W+ tr|C9JL14|C9JL14_HUMAN 287 PPSSFITCSS-DNTIRLWN 304 6778887666.*******8 PP == domain 5 score: 8.7 bits; conditional E-value: 0.2 EEEEEEETTSSEEEEEET CS WD40 13 vtslafspdgawlasGsd 30 ++s+++sp+g+ lasG++ tr|C9JL14|C9JL14_HUMAN 359 IRSVCVSPNGQHLASGDR 376 89***********98864 PP == domain 6 score: 4.6 bits; conditional E-value: 4.2 EESS.SSEEEEE...EETTSSE...EEEEETTSEEEE CS WD40 7 ltGH.ssvtsla...fspdgaw...lasGsdDgtvri 36 ++H s + +l + las+s+D+ +++ tr|C9JL14|C9JL14_HUMAN 394 VEAHdSEILCLEyskPDT---GlklLASASRDRLIHV 427 579966699997533333...24558999****9987 PP == domain 7 score: 10.6 bits; conditional E-value: 0.051 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++tl+ H ss+t+++ + ++s Dg vr+ tr|C9JL14|C9JL14_HUMAN 436 LQQTLDEHsSSITAVK------F--AAS-DGQVRM 461 7899****888****4......4..344.444443 PP == domain 8 score: 7.9 bits; conditional E-value: 0.36 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++++p+g ++a+++ D+++ i+d tr|C9JL14|C9JL14_HUMAN 543 KVQTDPSGIYIATSCSDKNLSIFD 566 6789*******96644*****998 PP == domain 9 score: 16.8 bits; conditional E-value: 0.00055 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+c+ t GHs vt+++fs d + l+s s D + +W tr|C9JL14|C9JL14_HUMAN 570 GECVATMFGHSEiVTGMKFSNDCKHLISVSGDSCIFVW 607 68999999**6657************98766******* PP >> tr|E7EP77|E7EP77_HUMAN Uncharacterized protein OS=Homo sapiens GN=WDR17 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.2 0.0018 0.15 6 38 .] 54 88 .. 49 88 .. 0.82 2 ! 20.3 0.1 4.4e-05 0.0035 5 38 .] 364 398 .. 360 398 .. 0.84 3 ? 9.3 0.3 0.13 10 3 34 .. 447 481 .. 445 483 .. 0.77 4 ? 10.5 0.0 0.056 4.6 2 37 .. 489 525 .. 488 525 .. 0.79 5 ! 30.1 0.3 3.5e-08 2.8e-06 2 38 .] 533 571 .. 532 571 .. 0.83 6 ! 22.5 0.1 8.9e-06 0.00072 3 38 .] 577 614 .. 575 614 .. 0.85 7 ! 18.7 0.5 0.00014 0.011 1 38 [] 618 657 .. 618 657 .. 0.91 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.0018 EEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + + H + +t+++++p+++ l asGs D+ v iW+ tr|E7EP77|E7EP77_HUMAN 54 IMSEHkKTITAISWCPHNPDLfASGSTDNLVIIWN 88 4678*888****977777776379999*******8 PP == domain 2 score: 20.3 bits; conditional E-value: 4.4e-05 EEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 r l GH + +++f pd + l a++s Dgt+++Wd tr|E7EP77|E7EP77_HUMAN 364 RDL-GHvETIFDCKFKPDDPNLlATASFDGTIKVWD 398 555.9*888************7368899*******9 PP == domain 3 score: 9.3 bits; conditional E-value: 0.13 EEEEEESS..SSEEEEE.EETTSSEEEEEETTSEE CS WD40 3 clrtltGH..ssvtsla.fspdgawlasGsdDgtv 34 ++ + H +++ ++a ++d++ +a++s Dg + tr|E7EP77|E7EP77_HUMAN 447 IIQRFNEHgtNGIFCIAwSHKDSKRIATCSSDGFC 481 567788898777****977777777**9988*977 PP == domain 4 score: 10.5 bits; conditional E-value: 0.056 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 + l++++ H v ++++s++++ +a+G++D +vr++ tr|E7EP77|E7EP77_HUMAN 489 KVLHKYK-HpAAVFGCDWSQNNKDmIATGCEDTNVRVY 525 6789997.8677****96666555478*********97 PP == domain 5 score: 30.1 bits; conditional E-value: 3.5e-08 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 q+l++++GH v ++++sp l+sGsdDgtvriWd tr|E7EP77|E7EP77_HUMAN 533 QPLKVFSGHtAKVFHVKWSPLREGiLCSGSDDGTVRIWD 571 799******666****7666666655689*********9 PP == domain 6 score: 22.5 bits; conditional E-value: 8.9e-06 EEEEEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 c+ +l GH +v++l w l+sGs+D t+++Wd tr|E7EP77|E7EP77_HUMAN 577 CINILNGHtAPVRGL------MWnteipylLISGSWDYTIKVWD 614 8999****888****......66666666667***********9 PP == domain 7 score: 18.7 bits; conditional E-value: 0.00014 TEEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+ t H +v++l +p+ ++ +as+s+D tvr+W+ tr|E7EP77|E7EP77_HUMAN 618 GTCVDTVYDHgADVYGLTCHPSRPFtMASCSRDSTVRLWS 657 578999999*888************989***********5 PP >> sp|Q15269|PWP2_HUMAN Periodic tryptophan protein 2 homolog OS=Homo sapiens GN=PWP2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.4 0.21 17 4 26 .. 90 112 .. 86 118 .. 0.73 2 ? 3.9 0.2 6.9 5.6e+02 14 32 .. 148 166 .. 138 171 .. 0.89 3 ? 5.5 0.4 2.1 1.7e+02 3 37 .. 322 358 .. 320 359 .. 0.72 4 ! 33.0 0.0 4.5e-09 3.6e-07 8 38 .] 370 401 .. 362 401 .. 0.87 5 ! 19.0 0.2 0.00012 0.0095 3 37 .. 407 442 .. 405 443 .. 0.89 6 ! 33.8 0.1 2.4e-09 2e-07 2 38 .] 492 529 .. 491 529 .. 0.95 7 ? 4.4 0.0 4.8 3.9e+02 13 37 .. 608 632 .. 595 633 .. 0.84 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.21 EEEEESS..SSEEEEEEETTSSEEE CS WD40 4 lrtltGH..ssvtslafspdgawla 26 l+++ H +sv+s++fspdg+ ++ sp|Q15269|PWP2_HUMAN 90 LHHF--HfkGSVHSVSFSPDGRKFV 112 5663..55344**********9765 PP == domain 2 score: 3.9 bits; conditional E-value: 6.9 EEEEEETTSSEEEEEETTS CS WD40 14 tslafspdgawlasGsdDg 32 t++++ +d++ ++ Gs+D sp|Q15269|PWP2_HUMAN 148 TCIDWTDDSRCFVVGSKDM 166 8***************996 PP == domain 3 score: 5.5 bits; conditional E-value: 2.1 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriW 37 ++++l+ +s+ s+a +++g+w+a +++ g + +W sp|Q15269|PWP2_HUMAN 322 LIHSLSISdQSIASVAINSSGDWIAfgCSG-LGQLLVW 358 6777776656799***********854334.6666666 PP == domain 4 score: 33.0 bits; conditional E-value: 4.5e-09 ESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ss.vtslafspdgawlasGsdDgtvriWd 38 GH +s v +la+spdg+++++G+dDg+v++W+ sp|Q15269|PWP2_HUMAN 370 QGHfNSmV-ALAYSPDGQYIVTGGDDGKVKVWN 401 5**99956.***********************8 PP == domain 5 score: 19.0 bits; conditional E-value: 0.00012 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c t+t H s+vt++ f g ++++s+Dgtvr + sp|Q15269|PWP2_HUMAN 407 CFVTFTEHsSGVTGVTFTATGYVVVTSSMDGTVRAF 442 7889****777**********************965 PP == domain 6 score: 33.8 bits; conditional E-value: 2.4e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l +l+GH +++++l+f+p ++ las+s+D+tvr+Wd sp|Q15269|PWP2_HUMAN 492 RLLDVLSGHeGPISGLCFNPMKSVLASASWDKTVRLWD 529 67889****999*************************9 PP == domain 7 score: 4.4 bits; conditional E-value: 4.8 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 t+l++s dg+ +++G++ + v i+ sp|Q15269|PWP2_HUMAN 608 FTALCYSADGHSILAGGMSKFVCIY 632 599*************999999887 PP >> sp|Q8IZU2|WDR17_HUMAN WD repeat-containing protein 17 OS=Homo sapiens GN=WDR17 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.2 0.0019 0.15 6 38 .] 78 112 .. 73 112 .. 0.82 2 ! 20.3 0.1 4.5e-05 0.0036 5 38 .] 388 422 .. 384 422 .. 0.84 3 ? 9.3 0.3 0.13 11 3 34 .. 471 505 .. 469 507 .. 0.77 4 ? 10.5 0.0 0.057 4.7 2 37 .. 513 549 .. 512 549 .. 0.79 5 ! 30.1 0.3 3.5e-08 2.9e-06 2 38 .] 557 595 .. 556 595 .. 0.83 6 ! 22.5 0.1 9.1e-06 0.00074 3 38 .] 601 638 .. 599 638 .. 0.85 7 ! 18.7 0.5 0.00014 0.011 1 38 [] 642 681 .. 642 681 .. 0.91 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.0019 EEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + + H + +t+++++p+++ l asGs D+ v iW+ sp|Q8IZU2|WDR17_HUMAN 78 IMSEHkKTITAISWCPHNPDLfASGSTDNLVIIWN 112 4678*888****977777776379999*******8 PP == domain 2 score: 20.3 bits; conditional E-value: 4.5e-05 EEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 r l GH + +++f pd + l a++s Dgt+++Wd sp|Q8IZU2|WDR17_HUMAN 388 RDL-GHvETIFDCKFKPDDPNLlATASFDGTIKVWD 422 555.9*888************7368899*******9 PP == domain 3 score: 9.3 bits; conditional E-value: 0.13 EEEEEESS..SSEEEEE.EETTSSEEEEEETTSEE CS WD40 3 clrtltGH..ssvtsla.fspdgawlasGsdDgtv 34 ++ + H +++ ++a ++d++ +a++s Dg + sp|Q8IZU2|WDR17_HUMAN 471 IIQRFNEHgtNGIFCIAwSHKDSKRIATCSSDGFC 505 567788898777****977777777**9988*977 PP == domain 4 score: 10.5 bits; conditional E-value: 0.057 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 + l++++ H v ++++s++++ +a+G++D +vr++ sp|Q8IZU2|WDR17_HUMAN 513 KVLHKYK-HpAAVFGCDWSQNNKDmIATGCEDTNVRVY 549 6789997.8677****96666555478*********97 PP == domain 5 score: 30.1 bits; conditional E-value: 3.5e-08 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 q+l++++GH v ++++sp l+sGsdDgtvriWd sp|Q8IZU2|WDR17_HUMAN 557 QPLKVFSGHtAKVFHVKWSPLREGiLCSGSDDGTVRIWD 595 799******666****7666666655689*********9 PP == domain 6 score: 22.5 bits; conditional E-value: 9.1e-06 EEEEEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 c+ +l GH +v++l w l+sGs+D t+++Wd sp|Q8IZU2|WDR17_HUMAN 601 CINILNGHtAPVRGL------MWnteipylLISGSWDYTIKVWD 638 8999****888****......66666666667***********9 PP == domain 7 score: 18.7 bits; conditional E-value: 0.00014 TEEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+ t H +v++l +p+ ++ +as+s+D tvr+W+ sp|Q8IZU2|WDR17_HUMAN 642 GTCVDTVYDHgADVYGLTCHPSRPFtMASCSRDSTVRLWS 681 578999999*888************989***********5 PP >> sp|Q7Z4S6-6|KI21A_HUMAN Isoform 6 of Kinesin-like protein KIF21A OS=Homo sapiens GN=KIF21A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.3 7.2e-07 5.8e-05 2 38 .] 1285 1320 .. 1284 1320 .. 0.95 2 ? 10.7 0.1 0.046 3.8 1 38 [] 1324 1361 .. 1324 1361 .. 0.95 3 ? 10.1 0.0 0.077 6.2 5 38 .] 1393 1425 .. 1389 1425 .. 0.88 4 ! 18.6 0.0 0.00016 0.013 2 38 .] 1430 1470 .. 1429 1470 .. 0.93 5 ? 5.0 0.0 3.1 2.5e+02 9 38 .] 1488 1516 .. 1479 1516 .. 0.71 6 ! 13.2 0.1 0.0076 0.62 4 38 .] 1524 1559 .. 1522 1559 .. 0.90 7 ! 21.7 0.0 1.6e-05 0.0013 3 38 .] 1565 1599 .. 1563 1599 .. 0.79 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 7.2e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+++ +GH + v ++ ++ ++l++Gs+D+t+++W+ sp|Q7Z4S6-6|KI21A_HUMAN 1285 QCIHIAEGHtKAVLCV--DSTDDLLFTGSKDRTCKVWN 1320 8********999****..99999999***********8 PP == domain 2 score: 10.7 bits; conditional E-value: 0.046 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq + +l GH ++v s++++ + +++++ s +++Wd sp|Q7Z4S6-6|KI21A_HUMAN 1324 GQEIMSLGGHpNNVVSVKYCNYTSLVFTVS-TSYIKVWD 1361 678999****99999***************.*******9 PP == domain 3 score: 10.1 bits; conditional E-value: 0.077 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 + +G + ++ +a +p g++l ++s + vr+Wd sp|Q7Z4S6-6|KI21A_HUMAN 1393 AIPSGENQINQIALNPTGTFLYAAS-GNAVRMWD 1425 56677788*****************.*******9 PP == domain 4 score: 18.6 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 q +++ltGH ++v +l s+ ++++++Gs+D+ ++++d sp|Q7Z4S6-6|KI21A_HUMAN 1430 QSTGKLTGHlGPVMCLTvdqISSGQDLIITGSKDHYIKMFD 1470 567889********************************998 PP == domain 5 score: 5.0 bits; conditional E-value: 3.1 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l + d+ l+sGs+D+ ++ Wd sp|Q7Z4S6-6|KI21A_HUMAN 1488 PHyDGIEALTIQGDN--LFSGSRDNGIKKWD 1516 466668888555554..559**********9 PP == domain 6 score: 13.2 bits; conditional E-value: 0.0076 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +H ++v++l + pd++ l+sG++ g +++W+ sp|Q7Z4S6-6|KI21A_HUMAN 1524 QQVPNAHkDWVCALGVVPDHPVLLSGCRGGILKVWN 1559 567789*666*************************8 PP == domain 7 score: 21.7 bits; conditional E-value: 1.6e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +GH s+++++++ +++ ++++ dD+tvriW+ sp|Q7Z4S6-6|KI21A_HUMAN 1565 PVGEMKGHdSPINAICV--NSTHIFTAADDRTVRIWK 1599 678899**888998865..5555558888*******6 PP >> sp|Q7Z4S6-3|KI21A_HUMAN Isoform 3 of Kinesin-like protein KIF21A OS=Homo sapiens GN=KIF21A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.3 7.2e-07 5.8e-05 2 38 .] 1291 1326 .. 1290 1326 .. 0.95 2 ? 10.7 0.1 0.047 3.8 1 38 [] 1330 1367 .. 1330 1367 .. 0.95 3 ? 10.1 0.0 0.077 6.2 5 38 .] 1399 1431 .. 1395 1431 .. 0.88 4 ! 18.6 0.0 0.00016 0.013 2 38 .] 1436 1476 .. 1435 1476 .. 0.93 5 ? 5.0 0.0 3.1 2.6e+02 9 38 .] 1494 1522 .. 1485 1522 .. 0.71 6 ! 13.2 0.1 0.0077 0.62 4 38 .] 1530 1565 .. 1528 1565 .. 0.90 7 ! 21.7 0.0 1.6e-05 0.0013 3 38 .] 1571 1605 .. 1569 1605 .. 0.79 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 7.2e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+++ +GH + v ++ ++ ++l++Gs+D+t+++W+ sp|Q7Z4S6-3|KI21A_HUMAN 1291 QCIHIAEGHtKAVLCV--DSTDDLLFTGSKDRTCKVWN 1326 8********999****..99999999***********8 PP == domain 2 score: 10.7 bits; conditional E-value: 0.047 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq + +l GH ++v s++++ + +++++ s +++Wd sp|Q7Z4S6-3|KI21A_HUMAN 1330 GQEIMSLGGHpNNVVSVKYCNYTSLVFTVS-TSYIKVWD 1367 678999****99999***************.*******9 PP == domain 3 score: 10.1 bits; conditional E-value: 0.077 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 + +G + ++ +a +p g++l ++s + vr+Wd sp|Q7Z4S6-3|KI21A_HUMAN 1399 AIPSGENQINQIALNPTGTFLYAAS-GNAVRMWD 1431 56677788*****************.*******9 PP == domain 4 score: 18.6 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 q +++ltGH ++v +l s+ ++++++Gs+D+ ++++d sp|Q7Z4S6-3|KI21A_HUMAN 1436 QSTGKLTGHlGPVMCLTvdqISSGQDLIITGSKDHYIKMFD 1476 567889********************************998 PP == domain 5 score: 5.0 bits; conditional E-value: 3.1 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l + d+ l+sGs+D+ ++ Wd sp|Q7Z4S6-3|KI21A_HUMAN 1494 PHyDGIEALTIQGDN--LFSGSRDNGIKKWD 1522 466668888555554..559**********9 PP == domain 6 score: 13.2 bits; conditional E-value: 0.0077 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +H ++v++l + pd++ l+sG++ g +++W+ sp|Q7Z4S6-3|KI21A_HUMAN 1530 QQVPNAHkDWVCALGVVPDHPVLLSGCRGGILKVWN 1565 567789*666*************************8 PP == domain 7 score: 21.7 bits; conditional E-value: 1.6e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +GH s+++++++ +++ ++++ dD+tvriW+ sp|Q7Z4S6-3|KI21A_HUMAN 1571 PVGEMKGHdSPINAICV--NSTHIFTAADDRTVRIWK 1605 678899**888998865..5555558888*******6 PP >> sp|Q7Z4S6-5|KI21A_HUMAN Isoform 5 of Kinesin-like protein KIF21A OS=Homo sapiens GN=KIF21A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.3 7.2e-07 5.9e-05 2 38 .] 1301 1336 .. 1300 1336 .. 0.95 2 ? 10.7 0.1 0.047 3.8 1 38 [] 1340 1377 .. 1340 1377 .. 0.95 3 ? 10.0 0.0 0.077 6.3 5 38 .] 1409 1441 .. 1405 1441 .. 0.88 4 ! 18.5 0.0 0.00016 0.013 2 38 .] 1446 1486 .. 1445 1486 .. 0.93 5 ? 4.9 0.0 3.2 2.6e+02 9 38 .] 1504 1532 .. 1495 1532 .. 0.71 6 ! 13.2 0.1 0.0077 0.63 4 38 .] 1540 1575 .. 1538 1575 .. 0.90 7 ! 21.7 0.0 1.6e-05 0.0013 3 38 .] 1581 1615 .. 1579 1615 .. 0.79 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 7.2e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+++ +GH + v ++ ++ ++l++Gs+D+t+++W+ sp|Q7Z4S6-5|KI21A_HUMAN 1301 QCIHIAEGHtKAVLCV--DSTDDLLFTGSKDRTCKVWN 1336 8********999****..99999999***********8 PP == domain 2 score: 10.7 bits; conditional E-value: 0.047 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq + +l GH ++v s++++ + +++++ s +++Wd sp|Q7Z4S6-5|KI21A_HUMAN 1340 GQEIMSLGGHpNNVVSVKYCNYTSLVFTVS-TSYIKVWD 1377 678999****99999***************.*******9 PP == domain 3 score: 10.0 bits; conditional E-value: 0.077 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 + +G + ++ +a +p g++l ++s + vr+Wd sp|Q7Z4S6-5|KI21A_HUMAN 1409 AIPSGENQINQIALNPTGTFLYAAS-GNAVRMWD 1441 56677788*****************.*******9 PP == domain 4 score: 18.5 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 q +++ltGH ++v +l s+ ++++++Gs+D+ ++++d sp|Q7Z4S6-5|KI21A_HUMAN 1446 QSTGKLTGHlGPVMCLTvdqISSGQDLIITGSKDHYIKMFD 1486 567889********************************998 PP == domain 5 score: 4.9 bits; conditional E-value: 3.2 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l + d+ l+sGs+D+ ++ Wd sp|Q7Z4S6-5|KI21A_HUMAN 1504 PHyDGIEALTIQGDN--LFSGSRDNGIKKWD 1532 466668888555554..559**********9 PP == domain 6 score: 13.2 bits; conditional E-value: 0.0077 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +H ++v++l + pd++ l+sG++ g +++W+ sp|Q7Z4S6-5|KI21A_HUMAN 1540 QQVPNAHkDWVCALGVVPDHPVLLSGCRGGILKVWN 1575 567789*666*************************8 PP == domain 7 score: 21.7 bits; conditional E-value: 1.6e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +GH s+++++++ +++ ++++ dD+tvriW+ sp|Q7Z4S6-5|KI21A_HUMAN 1581 PVGEMKGHdSPINAICV--NSTHIFTAADDRTVRIWK 1615 678899**888998865..5555558888*******6 PP >> sp|Q7Z4S6-2|KI21A_HUMAN Isoform 2 of Kinesin-like protein KIF21A OS=Homo sapiens GN=KIF21A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.3 7.3e-07 6e-05 2 38 .] 1325 1360 .. 1324 1360 .. 0.95 2 ? 10.7 0.1 0.048 3.9 1 38 [] 1364 1401 .. 1364 1401 .. 0.95 3 ? 10.0 0.0 0.079 6.4 5 38 .] 1433 1465 .. 1429 1465 .. 0.88 4 ! 18.5 0.0 0.00016 0.013 2 38 .] 1470 1510 .. 1469 1510 .. 0.93 5 ? 4.9 0.0 3.2 2.6e+02 9 38 .] 1528 1556 .. 1519 1556 .. 0.71 6 ! 13.2 0.1 0.0078 0.64 4 38 .] 1564 1599 .. 1562 1599 .. 0.90 7 ! 21.6 0.0 1.7e-05 0.0014 3 38 .] 1605 1639 .. 1603 1639 .. 0.79 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 7.3e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+++ +GH + v ++ ++ ++l++Gs+D+t+++W+ sp|Q7Z4S6-2|KI21A_HUMAN 1325 QCIHIAEGHtKAVLCV--DSTDDLLFTGSKDRTCKVWN 1360 8********999****..99999999***********8 PP == domain 2 score: 10.7 bits; conditional E-value: 0.048 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq + +l GH ++v s++++ + +++++ s +++Wd sp|Q7Z4S6-2|KI21A_HUMAN 1364 GQEIMSLGGHpNNVVSVKYCNYTSLVFTVS-TSYIKVWD 1401 678999****99999***************.*******9 PP == domain 3 score: 10.0 bits; conditional E-value: 0.079 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 + +G + ++ +a +p g++l ++s + vr+Wd sp|Q7Z4S6-2|KI21A_HUMAN 1433 AIPSGENQINQIALNPTGTFLYAAS-GNAVRMWD 1465 56677788*****************.*******9 PP == domain 4 score: 18.5 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 q +++ltGH ++v +l s+ ++++++Gs+D+ ++++d sp|Q7Z4S6-2|KI21A_HUMAN 1470 QSTGKLTGHlGPVMCLTvdqISSGQDLIITGSKDHYIKMFD 1510 567889********************************998 PP == domain 5 score: 4.9 bits; conditional E-value: 3.2 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l + d+ l+sGs+D+ ++ Wd sp|Q7Z4S6-2|KI21A_HUMAN 1528 PHyDGIEALTIQGDN--LFSGSRDNGIKKWD 1556 466668888555554..559**********9 PP == domain 6 score: 13.2 bits; conditional E-value: 0.0078 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +H ++v++l + pd++ l+sG++ g +++W+ sp|Q7Z4S6-2|KI21A_HUMAN 1564 QQVPNAHkDWVCALGVVPDHPVLLSGCRGGILKVWN 1599 567789*666*************************8 PP == domain 7 score: 21.6 bits; conditional E-value: 1.7e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +GH s+++++++ +++ ++++ dD+tvriW+ sp|Q7Z4S6-2|KI21A_HUMAN 1605 PVGEMKGHdSPINAICV--NSTHIFTAADDRTVRIWK 1639 678899**888998865..5555558888*******6 PP >> tr|F8WCP6|F8WCP6_HUMAN Kinesin-like protein KIF21A OS=Homo sapiens GN=KIF21A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.3 7.4e-07 6e-05 2 38 .] 1339 1374 .. 1338 1374 .. 0.95 2 ? 10.7 0.1 0.048 3.9 1 38 [] 1378 1415 .. 1378 1415 .. 0.95 3 ? 10.0 0.0 0.079 6.4 5 38 .] 1447 1479 .. 1443 1479 .. 0.88 4 ! 18.5 0.0 0.00016 0.013 2 38 .] 1484 1524 .. 1483 1524 .. 0.93 5 ? 4.9 0.0 3.3 2.6e+02 9 38 .] 1542 1570 .. 1533 1570 .. 0.71 6 ! 13.2 0.1 0.0079 0.64 4 38 .] 1578 1613 .. 1576 1613 .. 0.90 7 ! 21.6 0.0 1.7e-05 0.0014 3 38 .] 1619 1653 .. 1617 1653 .. 0.79 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 7.4e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+++ +GH + v ++ ++ ++l++Gs+D+t+++W+ tr|F8WCP6|F8WCP6_HUMAN 1339 QCIHIAEGHtKAVLCV--DSTDDLLFTGSKDRTCKVWN 1374 8********999****..99999999***********8 PP == domain 2 score: 10.7 bits; conditional E-value: 0.048 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq + +l GH ++v s++++ + +++++ s +++Wd tr|F8WCP6|F8WCP6_HUMAN 1378 GQEIMSLGGHpNNVVSVKYCNYTSLVFTVS-TSYIKVWD 1415 678999****99999***************.*******9 PP == domain 3 score: 10.0 bits; conditional E-value: 0.079 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 + +G + ++ +a +p g++l ++s + vr+Wd tr|F8WCP6|F8WCP6_HUMAN 1447 AIPSGENQINQIALNPTGTFLYAAS-GNAVRMWD 1479 56677788*****************.*******9 PP == domain 4 score: 18.5 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 q +++ltGH ++v +l s+ ++++++Gs+D+ ++++d tr|F8WCP6|F8WCP6_HUMAN 1484 QSTGKLTGHlGPVMCLTvdqISSGQDLIITGSKDHYIKMFD 1524 567889********************************998 PP == domain 5 score: 4.9 bits; conditional E-value: 3.3 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l + d+ l+sGs+D+ ++ Wd tr|F8WCP6|F8WCP6_HUMAN 1542 PHyDGIEALTIQGDN--LFSGSRDNGIKKWD 1570 466668888555554..559**********9 PP == domain 6 score: 13.2 bits; conditional E-value: 0.0079 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +H ++v++l + pd++ l+sG++ g +++W+ tr|F8WCP6|F8WCP6_HUMAN 1578 QQVPNAHkDWVCALGVVPDHPVLLSGCRGGILKVWN 1613 567789*666*************************8 PP == domain 7 score: 21.6 bits; conditional E-value: 1.7e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +GH s+++++++ +++ ++++ dD+tvriW+ tr|F8WCP6|F8WCP6_HUMAN 1619 PVGEMKGHdSPINAICV--NSTHIFTAADDRTVRIWK 1653 678899**888998865..5555558888*******6 PP >> sp|Q7Z4S6|KI21A_HUMAN Kinesin-like protein KIF21A OS=Homo sapiens GN=KIF21A PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.3 7.4e-07 6e-05 2 38 .] 1338 1373 .. 1337 1373 .. 0.95 2 ? 10.7 0.1 0.048 3.9 1 38 [] 1377 1414 .. 1377 1414 .. 0.95 3 ? 10.0 0.0 0.079 6.4 5 38 .] 1446 1478 .. 1442 1478 .. 0.88 4 ! 18.5 0.0 0.00016 0.013 2 38 .] 1483 1523 .. 1482 1523 .. 0.93 5 ? 4.9 0.0 3.2 2.6e+02 9 38 .] 1541 1569 .. 1532 1569 .. 0.71 6 ! 13.2 0.1 0.0079 0.64 4 38 .] 1577 1612 .. 1575 1612 .. 0.90 7 ! 21.6 0.0 1.7e-05 0.0014 3 38 .] 1618 1652 .. 1616 1652 .. 0.79 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 7.4e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+++ +GH + v ++ ++ ++l++Gs+D+t+++W+ sp|Q7Z4S6|KI21A_HUMAN 1338 QCIHIAEGHtKAVLCV--DSTDDLLFTGSKDRTCKVWN 1373 8********999****..99999999***********8 PP == domain 2 score: 10.7 bits; conditional E-value: 0.048 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq + +l GH ++v s++++ + +++++ s +++Wd sp|Q7Z4S6|KI21A_HUMAN 1377 GQEIMSLGGHpNNVVSVKYCNYTSLVFTVS-TSYIKVWD 1414 678999****99999***************.*******9 PP == domain 3 score: 10.0 bits; conditional E-value: 0.079 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 + +G + ++ +a +p g++l ++s + vr+Wd sp|Q7Z4S6|KI21A_HUMAN 1446 AIPSGENQINQIALNPTGTFLYAAS-GNAVRMWD 1478 56677788*****************.*******9 PP == domain 4 score: 18.5 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 q +++ltGH ++v +l s+ ++++++Gs+D+ ++++d sp|Q7Z4S6|KI21A_HUMAN 1483 QSTGKLTGHlGPVMCLTvdqISSGQDLIITGSKDHYIKMFD 1523 567889********************************998 PP == domain 5 score: 4.9 bits; conditional E-value: 3.2 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l + d+ l+sGs+D+ ++ Wd sp|Q7Z4S6|KI21A_HUMAN 1541 PHyDGIEALTIQGDN--LFSGSRDNGIKKWD 1569 466668888555554..559**********9 PP == domain 6 score: 13.2 bits; conditional E-value: 0.0079 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +H ++v++l + pd++ l+sG++ g +++W+ sp|Q7Z4S6|KI21A_HUMAN 1577 QQVPNAHkDWVCALGVVPDHPVLLSGCRGGILKVWN 1612 567789*666*************************8 PP == domain 7 score: 21.6 bits; conditional E-value: 1.7e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +GH s+++++++ +++ ++++ dD+tvriW+ sp|Q7Z4S6|KI21A_HUMAN 1618 PVGEMKGHdSPINAICV--NSTHIFTAADDRTVRIWK 1652 678899**888998865..5555558888*******6 PP >> sp|Q7Z4S6-4|KI21A_HUMAN Isoform 4 of Kinesin-like protein KIF21A OS=Homo sapiens GN=KIF21A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.3 7.4e-07 6e-05 2 38 .] 1339 1374 .. 1338 1374 .. 0.95 2 ? 10.7 0.1 0.048 3.9 1 38 [] 1378 1415 .. 1378 1415 .. 0.95 3 ? 10.0 0.0 0.079 6.4 5 38 .] 1447 1479 .. 1443 1479 .. 0.88 4 ! 18.5 0.0 0.00016 0.013 2 38 .] 1484 1524 .. 1483 1524 .. 0.93 5 ? 4.9 0.0 3.3 2.6e+02 9 38 .] 1542 1570 .. 1533 1570 .. 0.71 6 ! 13.2 0.1 0.0079 0.64 4 38 .] 1578 1613 .. 1576 1613 .. 0.90 7 ! 21.6 0.0 1.7e-05 0.0014 3 38 .] 1619 1653 .. 1617 1653 .. 0.79 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 7.4e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+++ +GH + v ++ ++ ++l++Gs+D+t+++W+ sp|Q7Z4S6-4|KI21A_HUMAN 1339 QCIHIAEGHtKAVLCV--DSTDDLLFTGSKDRTCKVWN 1374 8********999****..99999999***********8 PP == domain 2 score: 10.7 bits; conditional E-value: 0.048 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq + +l GH ++v s++++ + +++++ s +++Wd sp|Q7Z4S6-4|KI21A_HUMAN 1378 GQEIMSLGGHpNNVVSVKYCNYTSLVFTVS-TSYIKVWD 1415 678999****99999***************.*******9 PP == domain 3 score: 10.0 bits; conditional E-value: 0.079 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 + +G + ++ +a +p g++l ++s + vr+Wd sp|Q7Z4S6-4|KI21A_HUMAN 1447 AIPSGENQINQIALNPTGTFLYAAS-GNAVRMWD 1479 56677788*****************.*******9 PP == domain 4 score: 18.5 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 q +++ltGH ++v +l s+ ++++++Gs+D+ ++++d sp|Q7Z4S6-4|KI21A_HUMAN 1484 QSTGKLTGHlGPVMCLTvdqISSGQDLIITGSKDHYIKMFD 1524 567889********************************998 PP == domain 5 score: 4.9 bits; conditional E-value: 3.3 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l + d+ l+sGs+D+ ++ Wd sp|Q7Z4S6-4|KI21A_HUMAN 1542 PHyDGIEALTIQGDN--LFSGSRDNGIKKWD 1570 466668888555554..559**********9 PP == domain 6 score: 13.2 bits; conditional E-value: 0.0079 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +H ++v++l + pd++ l+sG++ g +++W+ sp|Q7Z4S6-4|KI21A_HUMAN 1578 QQVPNAHkDWVCALGVVPDHPVLLSGCRGGILKVWN 1613 567789*666*************************8 PP == domain 7 score: 21.6 bits; conditional E-value: 1.7e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +GH s+++++++ +++ ++++ dD+tvriW+ sp|Q7Z4S6-4|KI21A_HUMAN 1619 PVGEMKGHdSPINAICV--NSTHIFTAADDRTVRIWK 1653 678899**888998865..5555558888*******6 PP >> tr|C9JG97|C9JG97_HUMAN Angio-associated migratory cell protein OS=Homo sapiens GN=AAMP PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.054 4.4 10 37 .. 71 100 .. 65 101 .. 0.87 2 ! 23.2 0.1 5.4e-06 0.00044 2 37 .. 106 142 .. 105 143 .. 0.91 3 ? 4.0 0.1 6.3 5.1e+02 17 37 .. 162 182 .. 147 183 .. 0.78 4 ! 16.0 0.0 0.001 0.082 15 38 .] 201 224 .. 189 224 .. 0.79 5 ! 19.7 0.1 7e-05 0.0056 2 36 .. 229 267 .. 228 268 .. 0.86 6 ! 15.5 0.1 0.0014 0.12 3 38 .] 331 367 .. 329 367 .. 0.85 7 ! 13.7 0.0 0.0053 0.43 2 36 .. 372 407 .. 371 408 .. 0.85 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.054 S.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 10 H.ssvtslafspdgawla.sGsdDgtvriW 37 H sv +++ +p + la +G++D + +W tr|C9JG97|C9JG97_HUMAN 71 HsASVFCVSLDPKTNTLAvTGGEDDKAFVW 100 8667************9769******9999 PP == domain 2 score: 23.2 bits; conditional E-value: 5.4e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l ++ GH +svt+ fs+d++++a+G++ g +++W tr|C9JG97|C9JG97_HUMAN 106 ELLFECAGHkDSVTCAGFSHDSTLVATGDMSGLLKVW 142 6788899**777****************99******* PP == domain 3 score: 4.0 bits; conditional E-value: 6.3 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 ++p + l++G+ Dg+ +W tr|C9JG97|C9JG97_HUMAN 162 EWHPRAPVLLAGTADGNTWMW 182 39999*******99**99999 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 + ++ pdg+ + G +Dgt+riWd tr|C9JG97|C9JG97_HUMAN 201 CGRVLPDGKRAVVGYEDGTIRIWD 224 555789****999**********9 PP == domain 5 score: 19.7 bits; conditional E-value: 7e-05 EEEEEEE...SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtlt...GH.ssvtslafspdgawlasGsdDgtvri 36 +++++l+ GH ++ t++a ++dg+++++Gs D+ ++ tr|C9JG97|C9JG97_HUMAN 229 SPIHVLKgteGHqGPLTCVAANQDGSLILTGSVDCQAKL 267 688898766699888*******************98775 PP == domain 6 score: 15.5 bits; conditional E-value: 0.0014 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +lr+ H s++ l + a + ++s Dg vr+Wd tr|C9JG97|C9JG97_HUMAN 331 TLRHQCQHqSGIVQLLWEAGTAVVYTCSLDGIVRLWD 367 56665678778999999999999*************9 PP == domain 7 score: 13.7 bits; conditional E-value: 0.0053 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++l+ ++GH + ++a s+d +++++ s D++ ++ tr|C9JG97|C9JG97_HUMAN 372 RLLTDYRGHtAEILDFALSKDASLVVTTSGDHKAKV 407 67889****777************997655**9998 PP >> sp|Q9HC35-2|EMAL4_HUMAN Isoform 2 of Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens GN=EML4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.1 3.8e-05 0.0031 2 38 .] 242 289 .. 241 289 .. 0.84 2 ? 6.2 0.0 1.3 1.1e+02 11 37 .. 399 424 .. 387 425 .. 0.79 3 ! 13.0 0.0 0.0091 0.73 5 38 .] 445 479 .. 441 479 .. 0.87 4 ! 19.0 0.0 0.00011 0.009 6 38 .] 529 562 .. 525 562 .. 0.90 5 ? 5.1 0.0 2.8 2.2e+02 18 37 .. 625 644 .. 609 645 .. 0.79 6 ! 21.1 0.3 2.4e-05 0.002 7 38 .] 659 691 .. 653 691 .. 0.86 7 ! 18.9 1.1 0.00012 0.0097 3 38 .] 768 805 .. 766 805 .. 0.80 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 3.8e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 +++r++ GH ++v +la +pd+ +a+G + ++vr+Wd sp|Q9HC35-2|EMAL4_HUMAN 242 RTQRHYLGHtDCVKCLAIHPDKIRIATGqiaGVdkdgrplQPHVRVWD 289 679******777*************998665424678899*******9 PP == domain 2 score: 6.2 bits; conditional E-value: 1.3 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 ++v +laf +g+ l +G+ g iW sp|Q9HC35-2|EMAL4_HUMAN 399 KFVQCLAFLGNGDVL-TGDSGGVMLIW 424 459***********8.79658888889 PP == domain 3 score: 13.0 bits; conditional E-value: 0.0091 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++H +sv l+ ++g +l+ G++D+++ +Wd sp|Q9HC35-2|EMAL4_HUMAN 445 KQIKAHdGSVFTLCQMRNGMLLTGGGKDRKIILWD 479 56789*888**9999******98779********9 PP == domain 4 score: 19.0 bits; conditional E-value: 0.00011 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH + ++la++p +++l+++ D+ v +W+ sp|Q9HC35-2|EMAL4_HUMAN 529 EVQGHtDELWGLATHPFKDLLLTCAQDRQVCLWN 562 568**666*************************8 PP == domain 5 score: 5.1 bits; conditional E-value: 2.8 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 +s dg++la Gs D+ ++++ sp|Q9HC35-2|EMAL4_HUMAN 625 YSIDGTFLAVGSHDNFIYLY 644 566********99**99986 PP == domain 6 score: 21.1 bits; conditional E-value: 2.4e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tGH s +t+l++spd+++++s s D + Wd sp|Q9HC35-2|EMAL4_HUMAN 659 CTGHsSYITHLDWSPDNKYIMSNSGDYEILYWD 691 68**555*************97555*****998 PP == domain 7 score: 18.9 bits; conditional E-value: 0.00012 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + +++++H s+vt ++f ++ + +++G++D ++ W+ sp|Q9HC35-2|EMAL4_HUMAN 768 PSHKYSAHsSHVTNVSFTHNDSHlISTGGKDMSIIQWK 805 6899****888*****666666615699********95 PP >> sp|Q13685|AAMP_HUMAN Angio-associated migratory cell protein OS=Homo sapiens GN=AAMP PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.058 4.7 10 37 .. 90 119 .. 84 120 .. 0.87 2 ! 23.1 0.1 5.7e-06 0.00046 2 37 .. 125 161 .. 124 162 .. 0.91 3 ? 3.9 0.1 6.7 5.4e+02 17 37 .. 181 201 .. 166 202 .. 0.78 4 ! 15.9 0.0 0.0011 0.087 15 38 .] 220 243 .. 208 243 .. 0.79 5 ! 19.6 0.1 7.4e-05 0.006 2 36 .. 248 286 .. 247 287 .. 0.86 6 ! 15.4 0.1 0.0015 0.12 3 38 .] 350 386 .. 348 386 .. 0.85 7 ! 13.7 0.0 0.0056 0.45 2 36 .. 391 426 .. 390 427 .. 0.85 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.058 S.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 10 H.ssvtslafspdgawla.sGsdDgtvriW 37 H sv +++ +p + la +G++D + +W sp|Q13685|AAMP_HUMAN 90 HsASVFCVSLDPKTNTLAvTGGEDDKAFVW 119 8667************9769******9999 PP == domain 2 score: 23.1 bits; conditional E-value: 5.7e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l ++ GH +svt+ fs+d++++a+G++ g +++W sp|Q13685|AAMP_HUMAN 125 ELLFECAGHkDSVTCAGFSHDSTLVATGDMSGLLKVW 161 6788899**777****************99******* PP == domain 3 score: 3.9 bits; conditional E-value: 6.7 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 ++p + l++G+ Dg+ +W sp|Q13685|AAMP_HUMAN 181 EWHPRAPVLLAGTADGNTWMW 201 39999*******99**99999 PP == domain 4 score: 15.9 bits; conditional E-value: 0.0011 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 + ++ pdg+ + G +Dgt+riWd sp|Q13685|AAMP_HUMAN 220 CGRVLPDGKRAVVGYEDGTIRIWD 243 555789****999**********9 PP == domain 5 score: 19.6 bits; conditional E-value: 7.4e-05 EEEEEEE...SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtlt...GH.ssvtslafspdgawlasGsdDgtvri 36 +++++l+ GH ++ t++a ++dg+++++Gs D+ ++ sp|Q13685|AAMP_HUMAN 248 SPIHVLKgteGHqGPLTCVAANQDGSLILTGSVDCQAKL 286 688898766699888*******************98775 PP == domain 6 score: 15.4 bits; conditional E-value: 0.0015 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +lr+ H s++ l + a + ++s Dg vr+Wd sp|Q13685|AAMP_HUMAN 350 TLRHQCQHqSGIVQLLWEAGTAVVYTCSLDGIVRLWD 386 56665678778999999999999*************9 PP == domain 7 score: 13.7 bits; conditional E-value: 0.0056 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++l+ ++GH + ++a s+d +++++ s D++ ++ sp|Q13685|AAMP_HUMAN 391 RLLTDYRGHtAEILDFALSKDASLVVTTSGDHKAKV 426 67889****777************997655**9998 PP >> tr|C9JEH3|C9JEH3_HUMAN Angio-associated migratory cell protein OS=Homo sapiens GN=AAMP PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.058 4.7 10 37 .. 91 120 .. 85 121 .. 0.87 2 ! 23.1 0.1 5.7e-06 0.00046 2 37 .. 126 162 .. 125 163 .. 0.91 3 ? 3.9 0.1 6.7 5.4e+02 17 37 .. 182 202 .. 167 203 .. 0.78 4 ! 15.9 0.0 0.0011 0.087 15 38 .] 221 244 .. 209 244 .. 0.79 5 ! 19.6 0.1 7.4e-05 0.006 2 36 .. 249 287 .. 248 288 .. 0.86 6 ! 15.4 0.1 0.0015 0.12 3 38 .] 351 387 .. 349 387 .. 0.85 7 ! 13.7 0.0 0.0056 0.45 2 36 .. 392 427 .. 391 428 .. 0.85 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.058 S.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 10 H.ssvtslafspdgawla.sGsdDgtvriW 37 H sv +++ +p + la +G++D + +W tr|C9JEH3|C9JEH3_HUMAN 91 HsASVFCVSLDPKTNTLAvTGGEDDKAFVW 120 8667************9769******9999 PP == domain 2 score: 23.1 bits; conditional E-value: 5.7e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l ++ GH +svt+ fs+d++++a+G++ g +++W tr|C9JEH3|C9JEH3_HUMAN 126 ELLFECAGHkDSVTCAGFSHDSTLVATGDMSGLLKVW 162 6788899**777****************99******* PP == domain 3 score: 3.9 bits; conditional E-value: 6.7 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 ++p + l++G+ Dg+ +W tr|C9JEH3|C9JEH3_HUMAN 182 EWHPRAPVLLAGTADGNTWMW 202 39999*******99**99999 PP == domain 4 score: 15.9 bits; conditional E-value: 0.0011 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 + ++ pdg+ + G +Dgt+riWd tr|C9JEH3|C9JEH3_HUMAN 221 CGRVLPDGKRAVVGYEDGTIRIWD 244 555789****999**********9 PP == domain 5 score: 19.6 bits; conditional E-value: 7.4e-05 EEEEEEE...SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtlt...GH.ssvtslafspdgawlasGsdDgtvri 36 +++++l+ GH ++ t++a ++dg+++++Gs D+ ++ tr|C9JEH3|C9JEH3_HUMAN 249 SPIHVLKgteGHqGPLTCVAANQDGSLILTGSVDCQAKL 287 688898766699888*******************98775 PP == domain 6 score: 15.4 bits; conditional E-value: 0.0015 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +lr+ H s++ l + a + ++s Dg vr+Wd tr|C9JEH3|C9JEH3_HUMAN 351 TLRHQCQHqSGIVQLLWEAGTAVVYTCSLDGIVRLWD 387 56665678778999999999999*************9 PP == domain 7 score: 13.7 bits; conditional E-value: 0.0056 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++l+ ++GH + ++a s+d +++++ s D++ ++ tr|C9JEH3|C9JEH3_HUMAN 392 RLLTDYRGHtAEILDFALSKDASLVVTTSGDHKAKV 427 67889****777************997655**9998 PP >> tr|C9JXA5|C9JXA5_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (Fragment) OS=Homo sapiens G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.0 1.2e-06 0.0001 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 12.9 0.1 0.01 0.81 12 37 .. 99 124 .. 86 125 .. 0.85 3 ! 20.4 0.2 4.1e-05 0.0033 4 38 .] 136 170 .. 133 170 .. 0.90 4 ! 24.3 0.1 2.4e-06 0.00019 7 38 .] 180 212 .. 174 212 .. 0.87 5 ! 24.2 0.0 2.6e-06 0.00021 3 35 .. 218 251 .] 216 251 .] 0.95 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 1.2e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd tr|C9JXA5|C9JXA5_HUMAN 48 RRTLRGHlAKIYAMHWGTDSRLLVSASQDGKLIIWD 83 689****999*************************9 PP == domain 2 score: 12.9 bits; conditional E-value: 0.01 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +v +a+ p+g+++a+G+ D+ + i+ tr|C9JXA5|C9JXA5_HUMAN 99 WVMTCAYAPSGNFVACGGLDNICSIY 124 488889*****************998 PP == domain 3 score: 20.4 bits; conditional E-value: 4.1e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + ++++f +d++ ++s++ D t+ +Wd tr|C9JXA5|C9JXA5_HUMAN 136 SRELPGHtGYLSCCRFLDDNQIITSSG-DTTCALWD 170 57899**666*************9999.*******9 PP == domain 4 score: 24.3 bits; conditional E-value: 2.4e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH ++v sl+ pdg+ ++sG D ++++Wd tr|C9JXA5|C9JXA5_HUMAN 180 FAGHsGDVMSLSLAPDGRTFVSGACDASIKLWD 212 78**777****************77*******9 PP == domain 5 score: 24.2 bits; conditional E-value: 2.6e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvr 35 c +t+ GH s+++++af p+g +++GsdD t+r tr|C9JXA5|C9JXA5_HUMAN 218 CRQTFIGHeSDINAVAFFPNGYAFTTGSDDATCR 251 889*****999*******************9998 PP >> tr|F8WC21|F8WC21_HUMAN Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens GN=MAPKBP1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 0.0069 0.56 4 37 .. 15 51 .. 13 51 .. 0.79 2 ! 13.1 0.1 0.0081 0.66 12 37 .. 66 91 .. 56 91 .. 0.90 3 ! 13.0 0.1 0.0091 0.74 5 38 .] 161 188 .. 157 188 .. 0.70 4 ! 14.2 0.1 0.0037 0.3 15 38 .] 231 254 .. 207 254 .. 0.86 5 ? 8.8 0.0 0.2 16 13 30 .. 315 332 .. 306 339 .. 0.83 6 ? 4.6 0.0 4 3.2e+02 7 36 .. 350 383 .. 342 385 .. 0.71 7 ? 10.7 0.0 0.049 4 3 36 .. 392 417 .. 390 428 .. 0.63 8 ? 8.0 0.0 0.35 28 15 38 .] 499 522 .. 481 522 .. 0.76 9 ! 16.9 0.3 0.00053 0.043 1 37 [. 526 563 .. 526 564 .. 0.88 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.0069 EEEEESSSS.EEEEEEETTSSEEEEEET..TSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsd..DgtvriW 37 + +l H+ v ++afsp+ ++++s ++ D v +W tr|F8WC21|F8WC21_HUMAN 15 VAELQEHKYgVACVAFSPSAKYIVSVGYqhDMIVNVW 51 5678889455************99755223**99999 PP == domain 2 score: 13.1 bits; conditional E-value: 0.0081 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 s vt+++fs d +++++++ ++++++W tr|F8WC21|F8WC21_HUMAN 66 SrVTAVSFSEDCSYFVTAG-NRHIKFW 91 349****************.******* PP == domain 3 score: 13.0 bits; conditional E-value: 0.0091 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 rt +H ++ s +++++++G+ Dgtvr+++ tr|F8WC21|F8WC21_HUMAN 161 RTTVAH-CI-----SVSQDYIFCGCADGTVRLFN 188 555566.44.....335588889*99******97 PP == domain 4 score: 14.2 bits; conditional E-value: 0.0037 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +l f+p ++wl++ D+++++Wd tr|F8WC21|F8WC21_HUMAN 231 ALTFDPTNQWLSCVYNDHSIYVWD 254 677*******965578*******9 PP == domain 5 score: 8.8 bits; conditional E-value: 0.2 EEEEEEETTSSEEEEEET CS WD40 13 vtslafspdgawlasGsd 30 ++s+++sp+g+ lasG++ tr|F8WC21|F8WC21_HUMAN 315 IRSVCVSPNGQHLASGDR 332 89***********98864 PP == domain 6 score: 4.6 bits; conditional E-value: 4 EESS.SSEEEEE...EETTSSE...EEEEETTSEEEE CS WD40 7 ltGH.ssvtsla...fspdgaw...lasGsdDgtvri 36 ++H s + +l + las+s+D+ +++ tr|F8WC21|F8WC21_HUMAN 350 VEAHdSEILCLEyskPDT---GlklLASASRDRLIHV 383 579966699997533333...24558999****9987 PP == domain 7 score: 10.7 bits; conditional E-value: 0.049 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++tl+ H ss+t+++ + ++s Dg vr+ tr|F8WC21|F8WC21_HUMAN 392 LQQTLDEHsSSITAVK------F--AAS-DGQVRM 417 7899****888****4......4..344.444443 PP == domain 8 score: 8.0 bits; conditional E-value: 0.35 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++++p+g ++a+++ D+++ i+d tr|F8WC21|F8WC21_HUMAN 499 KVQTDPSGIYIATSCSDKNLSIFD 522 6789*******96644*****998 PP == domain 9 score: 16.9 bits; conditional E-value: 0.00053 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+c+ t GHs vt+++fs d + l+s s D + +W tr|F8WC21|F8WC21_HUMAN 526 GECVATMFGHSEiVTGMKFSNDCKHLISVSGDSCIFVW 563 68999999**6657************98766******* PP >> sp|Q9HC35|EMAL4_HUMAN Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens GN=EML4 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.1 4.1e-05 0.0033 2 38 .] 300 347 .. 299 347 .. 0.84 2 ? 6.1 0.0 1.4 1.1e+02 11 37 .. 457 482 .. 445 483 .. 0.79 3 ! 12.9 0.0 0.0097 0.79 5 38 .] 503 537 .. 499 537 .. 0.87 4 ! 18.9 0.0 0.00012 0.0097 6 38 .] 587 620 .. 583 620 .. 0.90 5 ? 5.0 0.0 2.9 2.4e+02 18 37 .. 683 702 .. 667 703 .. 0.79 6 ! 21.0 0.3 2.6e-05 0.0021 7 38 .] 717 749 .. 711 749 .. 0.86 7 ! 18.8 1.1 0.00013 0.01 3 38 .] 826 863 .. 824 863 .. 0.80 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 4.1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 +++r++ GH ++v +la +pd+ +a+G + ++vr+Wd sp|Q9HC35|EMAL4_HUMAN 300 RTQRHYLGHtDCVKCLAIHPDKIRIATGqiaGVdkdgrplQPHVRVWD 347 679******777*************998665424678899*******9 PP == domain 2 score: 6.1 bits; conditional E-value: 1.4 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 ++v +laf +g+ l +G+ g iW sp|Q9HC35|EMAL4_HUMAN 457 KFVQCLAFLGNGDVL-TGDSGGVMLIW 482 459***********8.79658888889 PP == domain 3 score: 12.9 bits; conditional E-value: 0.0097 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++H +sv l+ ++g +l+ G++D+++ +Wd sp|Q9HC35|EMAL4_HUMAN 503 KQIKAHdGSVFTLCQMRNGMLLTGGGKDRKIILWD 537 56789*888**9999******98779********9 PP == domain 4 score: 18.9 bits; conditional E-value: 0.00012 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH + ++la++p +++l+++ D+ v +W+ sp|Q9HC35|EMAL4_HUMAN 587 EVQGHtDELWGLATHPFKDLLLTCAQDRQVCLWN 620 568**666*************************8 PP == domain 5 score: 5.0 bits; conditional E-value: 2.9 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 +s dg++la Gs D+ ++++ sp|Q9HC35|EMAL4_HUMAN 683 YSIDGTFLAVGSHDNFIYLY 702 566********99**99986 PP == domain 6 score: 21.0 bits; conditional E-value: 2.6e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tGH s +t+l++spd+++++s s D + Wd sp|Q9HC35|EMAL4_HUMAN 717 CTGHsSYITHLDWSPDNKYIMSNSGDYEILYWD 749 68**555*************97555*****998 PP == domain 7 score: 18.8 bits; conditional E-value: 0.00013 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + +++++H s+vt ++f ++ + +++G++D ++ W+ sp|Q9HC35|EMAL4_HUMAN 826 PSHKYSAHsSHVTNVSFTHNDSHlISTGGKDMSIIQWK 863 6899****888*****666666615699********95 PP >> tr|B5MBZ0|B5MBZ0_HUMAN Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens GN=EML4 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.1 4.1e-05 0.0033 2 38 .] 311 358 .. 310 358 .. 0.84 2 ? 6.0 0.0 1.4 1.2e+02 11 37 .. 468 493 .. 456 494 .. 0.79 3 ! 12.9 0.0 0.0098 0.8 5 38 .] 514 548 .. 510 548 .. 0.87 4 ! 18.9 0.0 0.00012 0.0098 6 38 .] 598 631 .. 594 631 .. 0.90 5 ? 5.0 0.0 3 2.4e+02 18 37 .. 694 713 .. 678 714 .. 0.79 6 ! 21.0 0.3 2.6e-05 0.0021 7 38 .] 728 760 .. 722 760 .. 0.86 7 ! 18.8 1.1 0.00013 0.011 3 38 .] 837 874 .. 835 874 .. 0.80 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 4.1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 +++r++ GH ++v +la +pd+ +a+G + ++vr+Wd tr|B5MBZ0|B5MBZ0_HUMAN 311 RTQRHYLGHtDCVKCLAIHPDKIRIATGqiaGVdkdgrplQPHVRVWD 358 679******777*************998665424678899*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.4 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 ++v +laf +g+ l +G+ g iW tr|B5MBZ0|B5MBZ0_HUMAN 468 KFVQCLAFLGNGDVL-TGDSGGVMLIW 493 459***********8.79658888889 PP == domain 3 score: 12.9 bits; conditional E-value: 0.0098 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++H +sv l+ ++g +l+ G++D+++ +Wd tr|B5MBZ0|B5MBZ0_HUMAN 514 KQIKAHdGSVFTLCQMRNGMLLTGGGKDRKIILWD 548 56789*888**9999******98779********9 PP == domain 4 score: 18.9 bits; conditional E-value: 0.00012 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH + ++la++p +++l+++ D+ v +W+ tr|B5MBZ0|B5MBZ0_HUMAN 598 EVQGHtDELWGLATHPFKDLLLTCAQDRQVCLWN 631 568**666*************************8 PP == domain 5 score: 5.0 bits; conditional E-value: 3 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 +s dg++la Gs D+ ++++ tr|B5MBZ0|B5MBZ0_HUMAN 694 YSIDGTFLAVGSHDNFIYLY 713 566********99**99986 PP == domain 6 score: 21.0 bits; conditional E-value: 2.6e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tGH s +t+l++spd+++++s s D + Wd tr|B5MBZ0|B5MBZ0_HUMAN 728 CTGHsSYITHLDWSPDNKYIMSNSGDYEILYWD 760 68**555*************97555*****998 PP == domain 7 score: 18.8 bits; conditional E-value: 0.00013 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + +++++H s+vt ++f ++ + +++G++D ++ W+ tr|B5MBZ0|B5MBZ0_HUMAN 837 PSHKYSAHsSHVTNVSFTHNDSHlISTGGKDMSIIQWK 874 6899****888*****666666615699********95 PP >> sp|P54198-2|HIRA_HUMAN Isoform Short of Protein HIRA OS=Homo sapiens GN=HIRA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.2 0.0016 0.13 9 38 .] 10 44 .. 4 44 .. 0.85 2 ! 25.8 0.1 7.9e-07 6.4e-05 9 38 .] 68 98 .. 61 98 .. 0.90 3 ! 34.4 3.6 1.6e-09 1.3e-07 1 38 [] 121 159 .. 121 159 .. 0.95 4 ! 22.5 0.0 8.7e-06 0.0007 3 37 .. 166 201 .. 164 202 .. 0.89 5 ? 10.7 0.1 0.048 3.9 9 29 .. 221 241 .. 213 246 .. 0.79 6 ? 5.4 0.5 2.2 1.8e+02 7 37 .. 264 312 .. 258 312 .. 0.58 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0016 SS..SSEEEEEEETTSSEEEEEE...TTSEEEEEE CS WD40 9 GH..ssvtslafspdgawlasGs...dDgtvriWd 38 H +++ s++ +pdg+ +a+G+ d g+v iW+ sp|P54198-2|HIRA_HUMAN 10 NHngKPIFSVDIHPDGTKFATGGqgqDSGKVVIWN 44 686566****************86677*******8 PP == domain 2 score: 25.8 bits; conditional E-value: 7.9e-07 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +v+++++s +g +lasG+dD+ +++W+ sp|P54198-2|HIRA_HUMAN 68 NHlACVNCVRWSNSGMYLASGGDDKLIMVWK 98 68888*************************6 PP == domain 3 score: 34.4 bits; conditional E-value: 1.6e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++c+ +l+ H ++v ++a+sp+ awlas+s D+tv iW+ sp|P54198-2|HIRA_HUMAN 121 WRCVSILRNHsGDVMDVAWSPHDAWLASCSVDNTVVIWN 159 68********777*************************8 PP == domain 4 score: 22.5 bits; conditional E-value: 8.7e-06 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriW 37 l tl+GHs+ v +l ++p g+++as dD+++++W sp|P54198-2|HIRA_HUMAN 166 ILATLRGHSGlVKGLTWDPVGKYIASQADDRSLKVW 201 5789****7789***********986588******* PP == domain 5 score: 10.7 bits; conditional E-value: 0.048 SSSSEEEEEEETTSSEEEEEE CS WD40 9 GHssvtslafspdgawlasGs 29 G ++v l++spdg++l+s++ sp|P54198-2|HIRA_HUMAN 221 GTTHVLRLSWSPDGHYLVSAH 241 3344**************986 PP == domain 6 score: 5.4 bits; conditional E-value: 2.2 EESS.SSEEEEE...............EETTSSE..EEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla...............fspdgaw..lasGsdDgtvriW 37 + GH + vt ++ p+ ++ a Gs+D+++ +W sp|P54198-2|HIRA_HUMAN 264 FVGHrKAVTVVKfnpkifkkkqkngssAKPSCPYccCAVGSKDRSLSVW 312 5677666766655555555554444442222223324569********9 PP >> tr|H0YAM7|H0YAM7_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.6 0.2 3.1e-10 2.5e-08 3 38 .] 4 40 .. 2 40 .. 0.93 2 ! 24.8 1.0 1.6e-06 0.00013 9 38 .] 53 85 .. 43 85 .. 0.83 3 ! 24.4 0.2 2.2e-06 0.00018 7 38 .] 95 127 .. 89 127 .. 0.86 4 ! 23.3 0.1 5.2e-06 0.00042 2 38 .] 132 167 .. 131 167 .. 0.87 Alignments for each domain: == domain 1 score: 36.6 bits; conditional E-value: 3.1e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|H0YAM7|H0YAM7_HUMAN 4 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 40 678899******************************8 PP == domain 2 score: 24.8 bits; conditional E-value: 1.6e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|H0YAM7|H0YAM7_HUMAN 53 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 85 79666*************989***********8 PP == domain 3 score: 24.4 bits; conditional E-value: 2.2e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd tr|H0YAM7|H0YAM7_HUMAN 95 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 127 3499666*************************9 PP == domain 4 score: 23.3 bits; conditional E-value: 5.2e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+tl+G + +++l+fsp+ wl++++ ++++iWd tr|H0YAM7|H0YAM7_HUMAN 132 KHLYTLDGG-DiINALCFSPNRYWLCAAT-GPSIKIWD 167 778888887.448************9888.*******9 PP >> tr|F5H0S8|F5H0S8_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (Fragment) OS=Homo sapiens G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.0 1.2e-06 9.8e-05 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 13.4 0.0 0.0069 0.56 12 38 .] 99 125 .. 86 125 .. 0.86 3 ! 14.3 0.3 0.0036 0.29 4 38 .] 136 171 .. 133 171 .. 0.85 4 ! 33.6 0.1 2.7e-09 2.2e-07 1 38 [] 175 213 .. 175 213 .. 0.96 5 ! 19.7 0.1 7e-05 0.0057 10 38 .] 225 257 .. 218 257 .. 0.83 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.2e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ +Wd tr|F5H0S8|F5H0S8_HUMAN 48 RRTLRGHlAKIYAMHWATDSKLLVSASQDGKLIVWD 83 689****999*************************9 PP == domain 2 score: 13.4 bits; conditional E-value: 0.0069 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ tr|F5H0S8|F5H0S8_HUMAN 99 WVMTCAYAPSGNFVACGGLDNMCSIYN 125 488889******************997 PP == domain 3 score: 14.3 bits; conditional E-value: 0.0036 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l++H + ++++f +d++ ++s++d ++Wd tr|F5H0S8|F5H0S8_HUMAN 136 SRELSAHtGYLSCCRFLDDNNIVTSSGDTTCAKLWD 171 6899***666*************9999777777787 PP == domain 4 score: 33.6 bits; conditional E-value: 2.7e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c +t+tGH s++++++f p+g +++GsdD ++r++d tr|F5H0S8|F5H0S8_HUMAN 175 GTCRQTFTGHeSDINAICFFPNGEAICTGSDDASCRLFD 213 6799******999************************98 PP == domain 5 score: 19.7 bits; conditional E-value: 7e-05 SSS....EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss....vtslafspdgawlasGsdDgtvriWd 38 H s +ts+afs +g++l++G dD ++ +Wd tr|F5H0S8|F5H0S8_HUMAN 225 HESiicgITSVAFSLSGRLLFAGYDDFNCNVWD 257 72335559************************9 PP >> sp|Q6IA86-7|ELP2_HUMAN Isoform 7 of Elongator complex protein 2 OS=Homo sapiens GN=ELP2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.3 0.0084 0.68 4 37 .. 51 90 .. 48 91 .. 0.71 2 ? 8.4 0.0 0.25 20 6 38 .] 102 143 .. 98 143 .. 0.69 3 ? 9.2 0.1 0.14 12 24 38 .] 153 167 .. 150 167 .. 0.90 4 ? 11.0 0.0 0.038 3.1 5 37 .. 207 249 .. 204 249 .. 0.80 5 ! 16.3 0.0 0.00081 0.066 4 36 .. 311 344 .. 308 346 .. 0.84 6 ? 5.2 0.0 2.5 2.1e+02 4 29 .. 490 516 .. 487 530 .. 0.83 7 ! 16.8 0.0 0.00058 0.047 2 38 .] 535 572 .. 534 572 .. 0.86 8 ! 23.9 1.8 3.3e-06 0.00027 7 37 .. 595 626 .. 590 626 .. 0.88 9 ? 5.8 0.0 1.7 1.4e+02 24 36 .. 734 748 .. 699 750 .. 0.83 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.0084 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 ++ l GH v++++ sp+ ++ sG+ D+ v W sp|Q6IA86-7|ELP2_HUMAN 51 VTNLNGHtARVNCIQwickqdGSPSTELV-SGGSDNQVIHW 90 56789**6669999555555566666665.6766**99988 PP == domain 2 score: 8.4 bits; conditional E-value: 0.25 EEESS.SSEEEEE.......EETTSSE...EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgaw...lasGsdDgtvriWd 38 +l GH ++v+++ +p + ++s+ D vr+W+ sp|Q6IA86-7|ELP2_HUMAN 102 HLQGHeGPVYAVHavyqrrtSDPA--LctlIVSAAADSAVRLWS 143 789**8888888655566443333..2555567777*******5 PP == domain 3 score: 9.2 bits; conditional E-value: 0.14 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +las+s D+ +riW+ sp|Q6IA86-7|ELP2_HUMAN 153 FLASCSQDCLIRIWK 167 799***********6 PP == domain 4 score: 11.0 bits; conditional E-value: 0.038 EEEESS.SSEEEEE....EETTSSE.....EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla....fspdgaw.....lasGsdDgtvriW 37 ++l GH ++v+++ f +dg + l+s+s+D+t +W sp|Q6IA86-7|ELP2_HUMAN 207 TVLAGHeNWVNAVHwqpvFYKDGVLqqpvrLLSASMDKTMILW 249 5688**999****555555555555*****889999****999 PP == domain 5 score: 16.3 bits; conditional E-value: 0.00081 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++GH ++v +l ++p+g ++++ + D+t r+ sp|Q6IA86-7|ELP2_HUMAN 311 EIVISGHfDGVQDLVWDPEGEFIITVGTDQTTRL 344 56789**777************997666***998 PP == domain 6 score: 5.2 bits; conditional E-value: 2.5 EEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGs 29 +++l GH+ + ++ ++++++las++ sp|Q6IA86-7|ELP2_HUMAN 490 VQKLYGHGYeIFCVTCNSSKTLLASAC 516 67889**446*************9886 PP == domain 7 score: 16.8 bits; conditional E-value: 0.00058 EEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 ++++ l H s vt +afsp+ ++l++ s+D+t +W+ sp|Q6IA86-7|ELP2_HUMAN 535 KQVQNLVFH-SltVTQMAFSPNEKFLLAVSRDRTWSLWK 572 667778889.446**************99*********6 PP == domain 8 score: 23.9 bits; conditional E-value: 3.3e-06 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 + Hs ++s+++spd++++++Gs+D++v +W sp|Q6IA86-7|ELP2_HUMAN 595 TSVHSRiIWSCDWSPDSKYFFTGSRDKKVVVW 626 46796667************************ PP == domain 9 score: 5.8 bits; conditional E-value: 1.7 E..EEEEETTSEEEE CS WD40 24 w..lasGsdDgtvri 36 w +as+++D+tv+i sp|Q6IA86-7|ELP2_HUMAN 734 WlhFASCGEDHTVKI 748 5335999*******9 PP >> sp|Q8N0X2-2|SPG16_HUMAN Isoform 2 of Sperm-associated antigen 16 protein OS=Homo sapiens GN=SPAG16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.066 5.4 6 33 .. 198 226 .. 193 229 .. 0.82 2 ! 26.3 1.9 5.5e-07 4.5e-05 9 38 .] 243 273 .. 234 273 .. 0.85 3 ! 29.1 3.9 7.6e-08 6.2e-06 1 38 [] 277 315 .. 277 315 .. 0.94 4 ! 29.5 0.1 5.5e-08 4.4e-06 2 38 .] 320 357 .. 319 357 .. 0.93 5 ! 15.1 0.2 0.002 0.16 3 38 .] 363 399 .. 361 399 .. 0.93 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.066 EEESS.SSEEEEEEETTSSEEEEEETTSE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgt 33 +++ H +v++++ +p+++ l+s+++D+ sp|Q8N0X2-2|SPG16_HUMAN 198 IFRLHeLPVSCVSMQPHKDILVSCGEDRL 226 56668667*****************9986 PP == domain 2 score: 26.3 bits; conditional E-value: 5.5e-07 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++ ++++f+p+g+ la++s D tv++Wd sp|Q8N0X2-2|SPG16_HUMAN 243 GHtDWLSDCCFHPSGDKLATSSGDTTVKLWD 273 9*7779*************9978*******9 PP == domain 3 score: 29.1 bits; conditional E-value: 7.6e-08 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g+c+ t++GHs v+s+ +++ g+++as+s D+t +iWd sp|Q8N0X2-2|SPG16_HUMAN 277 GDCILTFEGHSRaVWSCTWHSCGNFVASSSLDKTSKIWD 315 689*******446*************************9 PP == domain 4 score: 29.5 bits; conditional E-value: 5.5e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c tl GH +sv+s+ f p ++ l+++s D+t+ iWd sp|Q8N0X2-2|SPG16_HUMAN 320 RCRCTLYGHtDSVNSIEFFPFSNTLLTSSADKTLSIWD 357 688999***888****************99*******9 PP == domain 5 score: 15.1 bits; conditional E-value: 0.002 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++l GH s+++ f+p g+++as++ g ++Wd sp|Q8N0X2-2|SPG16_HUMAN 363 CEQSLYGHmHSINDAIFDPRGHMIASCDACGVTKLWD 399 789999**999****************99*******9 PP >> sp|Q8TAF3|WDR48_HUMAN WD repeat-containing protein 48 OS=Homo sapiens GN=WDR48 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.067 5.4 11 38 .] 31 58 .. 25 58 .. 0.89 2 ! 17.9 0.6 0.00025 0.02 7 38 .] 71 103 .. 66 103 .. 0.80 3 ! 21.0 0.0 2.7e-05 0.0022 3 38 .] 109 145 .. 107 145 .. 0.93 4 ! 15.1 0.0 0.002 0.16 4 38 .] 161 196 .. 158 196 .. 0.92 5 ! 24.0 0.1 3e-06 0.00024 4 38 .] 203 238 .. 200 238 .. 0.90 6 ? 10.6 0.1 0.053 4.3 2 35 .. 243 277 .. 242 280 .. 0.88 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.067 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v++l+ +p + l+++++D +riW+ sp|Q8TAF3|WDR48_HUMAN 31 NGVNALQLDPALNRLFTAGRDSIIRIWS 58 56999999999999*99999*******5 PP == domain 2 score: 17.9 bits; conditional E-value: 0.00025 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H ++v+++ + +g+ l+s+s D tv++W+ sp|Q8TAF3|WDR48_HUMAN 71 MEHHtDWVNDIVLCCNGKTLISASSDTTVKVWN 103 566866678777777*****99988*******8 PP == domain 3 score: 21.0 bits; conditional E-value: 2.7e-05 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 c+ tl++H++ v +la+ +d+ ++as++ D+ + +Wd sp|Q8TAF3|WDR48_HUMAN 109 CMSTLRTHKDyVKALAYAKDKELVASAGLDRQIFLWD 145 999*****666**************9999*******9 PP == domain 4 score: 15.1 bits; conditional E-value: 0.002 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +l+G +s++sla ++ g+ ++sGs + +r+Wd sp|Q8TAF3|WDR48_HUMAN 161 TSSLSGNkDSIYSLAMNQLGTIIVSGSTEKVLRVWD 196 56899**777*************************9 PP == domain 5 score: 24.0 bits; conditional E-value: 3e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l+GH ++v +l ++dg+ +sGs Dgt+r+W+ sp|Q8TAF3|WDR48_HUMAN 203 LMKLKGHtDNVKALLLNRDGTQCLSGSSDGTIRLWS 238 7789***766****************99*******5 PP == domain 6 score: 10.6 bits; conditional E-value: 0.053 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvr 35 +c+ t++ H +v++l++++ + + sG++D++++ sp|Q8TAF3|WDR48_HUMAN 243 RCIATYRVHdEGVWALQVNDAFTHVYSGGRDRKIY 277 79*******777****888888889*******996 PP >> sp|O43818|U3IP2_HUMAN U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens GN=RRP9 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.2 0.002 0.16 4 37 .. 139 173 .. 137 174 .. 0.90 2 ! 22.3 0.0 1e-05 0.00084 8 37 .. 196 226 .. 191 227 .. 0.91 3 ! 23.8 0.4 3.6e-06 0.00029 2 38 .] 232 269 .. 231 269 .. 0.92 4 ! 15.7 0.0 0.0013 0.1 6 38 .] 278 311 .. 273 311 .. 0.71 5 ? 12.8 0.1 0.01 0.82 3 37 .. 316 350 .. 314 350 .. 0.77 6 ? 6.6 0.0 0.96 78 13 37 .. 379 403 .. 364 404 .. 0.81 7 ? 8.8 0.0 0.2 16 12 28 .. 423 439 .. 416 446 .. 0.84 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 0.002 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +r+l+GH s+t+l + pd + ++s+ +D+++ W sp|O43818|U3IP2_HUMAN 139 IRVLRGHqLSITCLVVTPDDSAIFSAAKDCSIIKW 173 689****877*****9999999999******9877 PP == domain 2 score: 22.3 bits; conditional E-value: 1e-05 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 GH s+v ++a s+dg++lasG++ + + iW sp|O43818|U3IP2_HUMAN 196 PGHsSHVLCMAISSDGKYLASGDRSKLILIW 226 69*888************************* PP == domain 3 score: 23.8 bits; conditional E-value: 3.6e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+l+t+tGH + v++laf + + l s s D++v++W+ sp|O43818|U3IP2_HUMAN 232 QHLYTFTGHrDAVSGLAFRRGTHQLYSTSHDRSVKVWN 269 7899*****888*************98888*******8 PP == domain 4 score: 15.7 bits; conditional E-value: 0.0013 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl GH + v +l+ + +++G++Dgtvr+W+ sp|O43818|U3IP2_HUMAN 278 TLFGHqDAVAALDALSRECCVTAGGRDGTVRVWK 311 56688555777754444444899**********6 PP == domain 5 score: 12.8 bits; conditional E-value: 0.01 EEEEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 + ++ GH +s+ ++ ++ ++sG dDg+v +W sp|O43818|U3IP2_HUMAN 316 SQLVFYGHqGSIDCI------HLineehMVSGADDGSVALW 350 577899**888*999......5544444579*********9 PP == domain 6 score: 6.6 bits; conditional E-value: 0.96 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++s+a + +++a+Gs vr+W sp|O43818|U3IP2_HUMAN 379 ISSVAALLNTDLVATGSHSSCVRLW 403 566666667788****99******* PP == domain 7 score: 8.8 bits; conditional E-value: 0.2 SEEEEEEETTSSEEEEE CS WD40 12 svtslafspdgawlasG 28 +++sl+fs++g++l++G sp|O43818|U3IP2_HUMAN 423 FINSLKFSSSGDFLVAG 439 39*************99 PP >> sp|O75037-2|KI21B_HUMAN Isoform 2 of Kinesin-like protein KIF21B OS=Homo sapiens GN=KIF21B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 9e-05 0.0073 2 38 .] 1286 1321 .. 1285 1321 .. 0.92 2 ? 9.4 0.1 0.12 9.9 2 38 .] 1326 1362 .. 1325 1362 .. 0.92 3 ? 9.9 0.0 0.083 6.8 10 37 .. 1400 1425 .. 1388 1426 .. 0.87 4 ! 16.7 0.0 0.00059 0.048 2 37 .. 1431 1470 .. 1430 1471 .. 0.91 5 ? 7.4 0.0 0.51 42 9 38 .] 1489 1517 .. 1480 1517 .. 0.79 6 ? 12.4 0.0 0.014 1.2 5 38 .] 1526 1560 .. 1522 1560 .. 0.89 7 ! 18.5 0.1 0.00016 0.013 3 38 .] 1566 1600 .. 1564 1600 .. 0.80 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 9e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+ +GH +++ +l + +l++Gs+D+++++W+ sp|O75037-2|KI21B_HUMAN 1286 QCVSMAEGHtKPILCL--DATDELLFTGSKDRSCKMWN 1321 6778889**999****..999999*************8 PP == domain 2 score: 9.4 bits; conditional E-value: 0.12 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q + l+GH ++v s+++++++ +++s s +++Wd sp|O75037-2|KI21B_HUMAN 1326 QEIAALKGHpNNVVSIKYCSHSGLVFSVS-TSYIKVWD 1362 678889***99999**********9999*.*******9 PP == domain 3 score: 9.9 bits; conditional E-value: 0.083 SSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriW 37 H ++ +a sp+g++l ++s + vriW sp|O75037-2|KI21B_HUMAN 1400 H-QINQIALSPSGTMLYAAS-GNAVRIW 1425 4.59****************.******* PP == domain 4 score: 16.7 bits; conditional E-value: 0.00059 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriW 37 q++++ltGH ++v +l + + ++++++Gs+D+ v+++ sp|O75037-2|KI21B_HUMAN 1431 QPVGKLTGHiGPVMCLTvtqTASQHDLVVTGSKDHYVKMF 1470 899*************998888888889*********986 PP == domain 5 score: 7.4 bits; conditional E-value: 0.51 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l g+ l+sGs+D+ ++ Wd sp|O75037-2|KI21B_HUMAN 1489 PHyDGIECL--AIQGDILFSGSRDNGIKKWD 1517 577779999..44788899***********9 PP == domain 6 score: 12.4 bits; conditional E-value: 0.014 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +H ++v++laf p ++l+s+++ g +++W+ sp|O75037-2|KI21B_HUMAN 1526 QIPNAHkDWVCALAFIPGRPMLLSACRAGVIKVWN 1560 66789*666*************************8 PP == domain 7 score: 18.5 bits; conditional E-value: 0.00016 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++++GH s++++++++ + + +++s D+ v++W+ sp|O75037-2|KI21B_HUMAN 1566 PIGEIKGHdSPINAICTNAKHIF-TASS-DCRVKLWN 1600 78899***888****77666666.4456.*******8 PP >> sp|O75037|KI21B_HUMAN Kinesin-like protein KIF21B OS=Homo sapiens GN=KIF21B PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 9.1e-05 0.0073 2 38 .] 1299 1334 .. 1298 1334 .. 0.92 2 ? 9.4 0.1 0.12 10 2 38 .] 1339 1375 .. 1338 1375 .. 0.92 3 ? 9.9 0.0 0.084 6.8 10 37 .. 1413 1438 .. 1401 1439 .. 0.87 4 ! 16.7 0.0 0.0006 0.048 2 37 .. 1444 1483 .. 1443 1484 .. 0.91 5 ? 7.4 0.0 0.52 42 9 38 .] 1502 1530 .. 1493 1530 .. 0.79 6 ? 12.3 0.0 0.014 1.2 5 38 .] 1539 1573 .. 1535 1573 .. 0.89 7 ! 18.5 0.1 0.00016 0.013 3 38 .] 1579 1613 .. 1577 1613 .. 0.80 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 9.1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+ +GH +++ +l + +l++Gs+D+++++W+ sp|O75037|KI21B_HUMAN 1299 QCVSMAEGHtKPILCL--DATDELLFTGSKDRSCKMWN 1334 6778889**999****..999999*************8 PP == domain 2 score: 9.4 bits; conditional E-value: 0.12 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q + l+GH ++v s+++++++ +++s s +++Wd sp|O75037|KI21B_HUMAN 1339 QEIAALKGHpNNVVSIKYCSHSGLVFSVS-TSYIKVWD 1375 678889***99999**********9999*.*******9 PP == domain 3 score: 9.9 bits; conditional E-value: 0.084 SSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriW 37 H ++ +a sp+g++l ++s + vriW sp|O75037|KI21B_HUMAN 1413 H-QINQIALSPSGTMLYAAS-GNAVRIW 1438 4.59****************.******* PP == domain 4 score: 16.7 bits; conditional E-value: 0.0006 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriW 37 q++++ltGH ++v +l + + ++++++Gs+D+ v+++ sp|O75037|KI21B_HUMAN 1444 QPVGKLTGHiGPVMCLTvtqTASQHDLVVTGSKDHYVKMF 1483 899*************998888888889*********986 PP == domain 5 score: 7.4 bits; conditional E-value: 0.52 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l g+ l+sGs+D+ ++ Wd sp|O75037|KI21B_HUMAN 1502 PHyDGIECL--AIQGDILFSGSRDNGIKKWD 1530 577779999..44788899***********9 PP == domain 6 score: 12.3 bits; conditional E-value: 0.014 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +H ++v++laf p ++l+s+++ g +++W+ sp|O75037|KI21B_HUMAN 1539 QIPNAHkDWVCALAFIPGRPMLLSACRAGVIKVWN 1573 66789*666*************************8 PP == domain 7 score: 18.5 bits; conditional E-value: 0.00016 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++++GH s++++++++ + + +++s D+ v++W+ sp|O75037|KI21B_HUMAN 1579 PIGEIKGHdSPINAICTNAKHIF-TASS-DCRVKLWN 1613 78899***888****77666666.4456.*******8 PP >> tr|H0Y8P4|H0Y8P4_HUMAN U3 small nucleolar RNA-associated protein 15 homolog (Fragment) OS=Homo sapiens GN=UTP15 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 0.0 0.11 8.8 14 38 .] 111 135 .. 97 135 .. 0.79 2 ! 29.6 0.1 5.1e-08 4.2e-06 2 38 .] 140 177 .. 139 177 .. 0.95 3 ! 14.7 0.0 0.0026 0.21 3 38 .] 183 220 .. 181 220 .. 0.88 4 ! 12.9 0.0 0.0096 0.78 9 38 .] 231 260 .. 224 260 .. 0.89 5 ! 25.6 0.1 9.7e-07 7.9e-05 1 37 [. 265 302 .. 265 303 .. 0.93 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.11 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++ f +dg++l++Gs+Dg v ++d tr|H0Y8P4|H0Y8P4_HUMAN 111 YCATFRQDGRLLVAGSEDGGVQLFD 135 688899*************999987 PP == domain 2 score: 29.6 bits; conditional E-value: 5.1e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +lr ++GH + v+ ++f d+ ++sG dD tv++Wd tr|H0Y8P4|H0Y8P4_HUMAN 140 APLRQFEGHtKAVHTVDFTADKYHVVSGADDYTVKLWD 177 5899*****999*************************9 PP == domain 3 score: 14.7 bits; conditional E-value: 0.0026 EEEEEESSSS.E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.v.tslafspdgawlasGsdDgtvriWd 38 + t++ Hs+ v +++a + +++++Gs+D+tv+++d tr|H0Y8P4|H0Y8P4_HUMAN 183 EILTFKEHSDyVrCGCASKLNPDLFITGSYDHTVKMFD 220 57899***556*999999999999***********998 PP == domain 4 score: 12.9 bits; conditional E-value: 0.0096 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H ++v s+ p+g +l+s++ + v++Wd tr|H0Y8P4|H0Y8P4_HUMAN 231 EHgQPVESVLLFPSGGLLVSAG-GRYVKVWD 260 58778*****************.*******9 PP == domain 5 score: 25.6 bits; conditional E-value: 9.7e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 gq+l +l+ H + vt+l+ s++g+ l+sGs D++v+++ tr|H0Y8P4|H0Y8P4_HUMAN 265 GQLLVSLKNHhKTVTCLCLSSSGQRLLSGSLDRKVKVY 302 6788999999899***********************98 PP >> sp|Q8TED0|UTP15_HUMAN U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens GN=UTP15 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.0 0.1 8.3 14 38 .] 84 108 .. 70 108 .. 0.79 2 ! 29.7 0.1 4.8e-08 3.9e-06 2 38 .] 113 150 .. 112 150 .. 0.95 3 ! 14.8 0.0 0.0025 0.2 3 38 .] 156 193 .. 154 193 .. 0.88 4 ! 13.0 0.0 0.009 0.73 9 38 .] 204 233 .. 197 233 .. 0.89 5 ! 25.6 0.1 9.1e-07 7.4e-05 1 37 [. 238 275 .. 238 276 .. 0.93 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.1 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++ f +dg++l++Gs+Dg v ++d sp|Q8TED0|UTP15_HUMAN 84 YCATFRQDGRLLVAGSEDGGVQLFD 108 688899*************999987 PP == domain 2 score: 29.7 bits; conditional E-value: 4.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +lr ++GH + v+ ++f d+ ++sG dD tv++Wd sp|Q8TED0|UTP15_HUMAN 113 APLRQFEGHtKAVHTVDFTADKYHVVSGADDYTVKLWD 150 5899*****999*************************9 PP == domain 3 score: 14.8 bits; conditional E-value: 0.0025 EEEEEESSSS.E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.v.tslafspdgawlasGsdDgtvriWd 38 + t++ Hs+ v +++a + +++++Gs+D+tv+++d sp|Q8TED0|UTP15_HUMAN 156 EILTFKEHSDyVrCGCASKLNPDLFITGSYDHTVKMFD 193 57899***556*999999999999***********998 PP == domain 4 score: 13.0 bits; conditional E-value: 0.009 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H ++v s+ p+g +l+s++ + v++Wd sp|Q8TED0|UTP15_HUMAN 204 EHgQPVESVLLFPSGGLLVSAG-GRYVKVWD 233 58778*****************.*******9 PP == domain 5 score: 25.6 bits; conditional E-value: 9.1e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 gq+l +l+ H + vt+l+ s++g+ l+sGs D++v+++ sp|Q8TED0|UTP15_HUMAN 238 GQLLVSLKNHhKTVTCLCLSSSGQRLLSGSLDRKVKVY 275 6788999999899***********************98 PP >> sp|Q8N1V2-3|WDR16_HUMAN Isoform 3 of WD repeat-containing protein 16 OS=Homo sapiens GN=WDR16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 0.0004 0.032 5 38 .] 37 73 .. 33 73 .. 0.82 2 ? 5.2 0.0 2.7 2.2e+02 25 37 .. 106 117 .. 91 118 .. 0.79 3 ? 6.5 0.1 1 84 8 37 .. 261 291 .. 230 292 .. 0.80 4 ? 10.4 0.0 0.061 4.9 9 37 .. 347 376 .. 338 377 .. 0.83 5 ! 16.6 0.0 0.00066 0.054 7 38 .] 389 421 .. 383 421 .. 0.90 6 ! 17.1 0.1 0.00047 0.038 4 38 .] 469 505 .. 466 505 .. 0.86 7 ! 15.9 0.1 0.0011 0.086 3 37 .. 511 546 .. 509 547 .. 0.85 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 0.0004 EEEESSSS.EEEEEEETTSSEEEE.EE.TTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlas.Gs.dDgtvriWd 38 l+ H++ + +lafsp+ +l+s G+ dDg+v +W+ sp|Q8N1V2-3|WDR16_HUMAN 37 ARLSLHKGkIEALAFSPNDLYLVSlGGpDDGSVVVWS 73 556679555*************9877788*******5 PP == domain 2 score: 5.2 bits; conditional E-value: 2.7 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 +++++ +gt+r+W sp|Q8N1V2-3|WDR16_HUMAN 106 FMTAG-NGTIRVW 117 45899.******* PP == domain 3 score: 6.5 bits; conditional E-value: 1 ESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGsdDgtvriW 37 t H + v ++ f+ a l a++ ++ +r+W sp|Q8N1V2-3|WDR16_HUMAN 261 TCHfDAVEDIVFPFGTAELfATCA-KKDIRVW 291 578555999987777777625667.******* PP == domain 4 score: 10.4 bits; conditional E-value: 0.061 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +vt++a+ +d + ++sG+ g vr+W sp|Q8N1V2-3|WDR16_HUMAN 347 AHrIGVTAIATTSDCKRVISGGGEGEVRVW 376 674349****999999999*988******* PP == domain 5 score: 16.6 bits; conditional E-value: 0.00066 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+ H ssv+++++ +++ +++s Dgt+ iWd sp|Q8N1V2-3|WDR16_HUMAN 389 LKEHkSSVSCIRVKRNNEECVTASTDGTCIIWD 421 789*888************999999*******9 PP == domain 6 score: 17.1 bits; conditional E-value: 0.00047 EEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 +r+l+G s+ +++++ ++g +++G+ D+ v++Wd sp|Q8N1V2-3|WDR16_HUMAN 469 IRELEGSlSGsINGMDITQEGVHFVTGGNDHLVKVWD 505 67788888444*************************9 PP == domain 7 score: 15.9 bits; conditional E-value: 0.0011 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++ GH +++t ++ sp +++++s s Dg + W sp|Q8N1V2-3|WDR16_HUMAN 511 VTHVGVGHsGNITRIRISPGNQYIVSVSADGAILRW 546 577888**655**************9999**99777 PP >> sp|Q9UM11-3|FZR_HUMAN Isoform 3 of Fizzy-related protein homolog OS=Homo sapiens GN=FZR1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.3 0.3 0.0074 0.6 10 38 .] 141 168 .. 132 168 .. 0.87 2 ? 9.5 0.0 0.11 9 1 34 [. 172 204 .. 172 208 .. 0.84 3 ! 27.5 0.0 2.3e-07 1.9e-05 5 38 .] 218 252 .. 214 252 .. 0.92 4 ! 20.3 0.0 4.6e-05 0.0037 3 38 .] 258 297 .. 256 297 .. 0.84 5 ? 5.5 0.1 2.1 1.7e+02 9 38 .] 310 340 .. 298 340 .. 0.71 6 ! 18.6 0.0 0.00015 0.012 4 38 .] 347 382 .. 344 382 .. 0.88 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 0.0074 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 svts+ +s g+++a G+ +g v iWd sp|Q9UM11-3|FZR_HUMAN 141 D-SVTSVGWSERGNLVAVGTHKGFVQIWD 168 4.7****************88*******9 PP == domain 2 score: 9.5 bits; conditional E-value: 0.11 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtv 34 g++l l+GH v +l aw l+sGs+D+ + sp|Q9UM11-3|FZR_HUMAN 172 GKKLSMLEGHtARVGAL------AWnaeqLSSGSRDRMI 204 5788999***666****......77777799*****988 PP == domain 3 score: 27.5 bits; conditional E-value: 2.3e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r l GH + v++l++s d+++lasG+ D+++ +W+ sp|Q9UM11-3|FZR_HUMAN 218 RRLQGHrQEVCGLKWSTDHQLLASGGNDNKLLVWN 252 6799**999*************************8 PP == domain 4 score: 20.3 bits; conditional E-value: 4.6e-05 EEEEEESS.SSEEEEEEETTSSEEE.EEE..TTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla.sGs..dDgtvriWd 38 +++ +t H v ++a+sp+++ l+ sG+ D+ +r+W+ sp|Q9UM11-3|FZR_HUMAN 258 PVQQYTEHlAAVKAIAWSPHQHGLLaSGGgtADRCIRFWN 297 78999***999************752664447*******8 PP == domain 5 score: 5.5 bits; conditional E-value: 2.1 SSSSEEEEEEETTSSEEEEE...ETTSEEEEEE CS WD40 9 GHssvtslafspdgawlasG...sdDgtvriWd 38 G v+ la+s++ + l+s s + + +W+ sp|Q9UM11-3|FZR_HUMAN 310 GS-QVCNLAWSKHANELVSThgyS-QNQILVWK 340 33.5999*9*********953233.99999995 PP == domain 6 score: 18.6 bits; conditional E-value: 0.00015 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + +ltGHs v la spdg +++G D t+r+W+ sp|Q9UM11-3|FZR_HUMAN 347 VAKLTGHSYrVLYLAMSPDGEAIVTGAGDETLRFWN 382 6789***558****************66*******8 PP >> tr|H3BSZ4|H3BSZ4_HUMAN Target of rapamycin complex subunit LST8 (Fragment) OS=Homo sapiens GN=MLST8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.068 5.5 24 37 .. 14 27 .. 8 28 .. 0.82 2 ? 7.6 0.0 0.46 37 3 38 .] 34 75 .. 32 75 .. 0.73 3 ! 23.7 0.1 3.8e-06 0.00031 6 38 .] 86 119 .. 81 119 .. 0.82 4 ! 21.1 0.0 2.5e-05 0.002 2 38 .] 126 162 .. 125 162 .. 0.96 5 ? 5.4 0.0 2.2 1.8e+02 12 38 .] 178 204 .. 165 204 .. 0.83 6 ! 24.0 0.0 3e-06 0.00025 15 37 .. 231 253 .. 214 254 .. 0.84 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.068 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W tr|H3BSZ4|H3BSZ4_HUMAN 14 ILATAGYDHTVRFW 27 5788888******* PP == domain 2 score: 7.6 bits; conditional E-value: 0.46 EEEEEESS..SSEEEEEEETTSSEEEEE......ETTSEEEEEE CS WD40 3 clrtltGH..ssvtslafspdgawlasG......sdDgtvriWd 38 c+rt H s v++l + pd +++a++ + +++r++d tr|H3BSZ4|H3BSZ4_HUMAN 34 CTRTVQ-HqdSQVNALEVTPDRSMIAAAvqpvslG-YQHIRMYD 75 788875.75444*************9863333234.99999987 PP == domain 3 score: 23.7 bits; conditional E-value: 3.8e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd tr|H3BSZ4|H3BSZ4_HUMAN 86 SYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 119 5555445688999********************9 PP == domain 4 score: 21.1 bits; conditional E-value: 2.5e-05 EEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtslafspdgawlasGsdDgtvriWd 38 qc+r++ ++++++ +p++a l+ G+ g ++iWd tr|H3BSZ4|H3BSZ4_HUMAN 126 QCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWD 162 8******9999*************************9 PP == domain 5 score: 5.4 bits; conditional E-value: 2.2 SEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 12 svtslafspdgawlasG.sdDgtvriWd 38 s+ts +pd +++a+ s g++++W+ tr|H3BSZ4|H3BSZ4_HUMAN 178 SITSAHIDPDASYMAAVnS-TGNCYVWN 204 389999*******997767.*******8 PP == domain 6 score: 24.0 bits; conditional E-value: 3e-06 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++fspd+++la++s D+t++iW tr|H3BSZ4|H3BSZ4_HUMAN 231 QCRFSPDSTLLATCSADQTCKIW 253 466******************** PP >> sp|A2RRH5-4|WDR27_HUMAN Isoform 4 of WD repeat-containing protein 27 OS=Homo sapiens GN=WDR27 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 1.4 1.2e+02 4 34 .. 64 97 .. 61 100 .. 0.66 2 ! 12.9 0.0 0.0097 0.78 6 38 .] 189 223 .. 182 223 .. 0.83 3 ? 12.3 0.1 0.015 1.2 13 38 .] 546 571 .. 537 571 .. 0.82 4 ! 32.6 0.3 5.6e-09 4.6e-07 6 38 .] 580 613 .. 577 613 .. 0.92 5 ! 19.2 0.0 0.0001 0.0082 2 37 .. 774 812 .. 773 813 .. 0.88 6 ? 6.7 0.1 0.87 70 5 23 .. 821 840 .. 817 851 .. 0.83 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 1.4 EEEEESS.SSEEEEE.EETTSSEEE.EEETTSEE CS WD40 4 lrtltGH.ssvtsla.fspdgawla.sGsdDgtv 34 l +l+GH +++t++a ++ +++l+ s+s D + sp|A2RRH5-4|WDR27_HUMAN 64 LLILRGHhQPITAMAfGNKVNPLLIcSASLDYVI 97 6789***999****76444444454144656555 PP == domain 2 score: 12.9 bits; conditional E-value: 0.0097 EEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 +l GH ++vt++ + l+s+s+D+ ++Wd sp|A2RRH5-4|WDR27_HUMAN 189 ELQGHlGPVTAVE------FcpwragtLISASEDRGFKVWD 223 689*********6......44446669899**********9 PP == domain 3 score: 12.3 bits; conditional E-value: 0.015 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v+++++s dg+wla+G ++ + ++d sp|A2RRH5-4|WDR27_HUMAN 546 VCCIQYSGDGQWLACGLANHLLLVFD 571 9*************995588877776 PP == domain 4 score: 32.6 bits; conditional E-value: 5.6e-09 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH + v+++++s+d +wl+s+ +Dgt+r+W+ sp|A2RRH5-4|WDR27_HUMAN 580 VFSGHdGAVNAVCWSQDRRWLLSAARDGTLRMWS 613 799**666****************9********5 PP == domain 5 score: 19.2 bits; conditional E-value: 0.0001 EEEEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ss..vtslafspdgawlasGsdDgtvriW 37 +c r+++GH + +++afsp g++ a+G +D++ +++ sp|A2RRH5-4|WDR27_HUMAN 774 RCERHFEGHpTRgyPCGIAFSPCGRFAACGAEDRHAYVY 812 699******7446789***********9999****9887 PP == domain 6 score: 6.7 bits; conditional E-value: 0.87 EEEESS.SSEEEEEEETTSS CS WD40 5 rtltGH.ssvtslafspdga 23 + l GH + vt++af+p+ + sp|A2RRH5-4|WDR27_HUMAN 821 HRLAGHtDTVTGVAFNPSAP 840 6688**666********976 PP >> tr|B4DXK8|B4DXK8_HUMAN U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens GN=UTP15 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.0 0.098 7.9 14 38 .] 65 89 .. 51 89 .. 0.79 2 ! 29.7 0.1 4.6e-08 3.7e-06 2 38 .] 94 131 .. 93 131 .. 0.95 3 ! 14.8 0.0 0.0024 0.19 3 38 .] 137 174 .. 135 174 .. 0.88 4 ! 13.1 0.0 0.0086 0.7 9 38 .] 185 214 .. 178 214 .. 0.89 5 ! 25.7 0.1 8.7e-07 7.1e-05 1 37 [. 219 256 .. 219 257 .. 0.93 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.098 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++ f +dg++l++Gs+Dg v ++d tr|B4DXK8|B4DXK8_HUMAN 65 YCATFRQDGRLLVAGSEDGGVQLFD 89 688899*************999987 PP == domain 2 score: 29.7 bits; conditional E-value: 4.6e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +lr ++GH + v+ ++f d+ ++sG dD tv++Wd tr|B4DXK8|B4DXK8_HUMAN 94 APLRQFEGHtKAVHTVDFTADKYHVVSGADDYTVKLWD 131 5899*****999*************************9 PP == domain 3 score: 14.8 bits; conditional E-value: 0.0024 EEEEEESSSS.E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.v.tslafspdgawlasGsdDgtvriWd 38 + t++ Hs+ v +++a + +++++Gs+D+tv+++d tr|B4DXK8|B4DXK8_HUMAN 137 EILTFKEHSDyVrCGCASKLNPDLFITGSYDHTVKMFD 174 57899***556*999999999999***********998 PP == domain 4 score: 13.1 bits; conditional E-value: 0.0086 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H ++v s+ p+g +l+s++ + v++Wd tr|B4DXK8|B4DXK8_HUMAN 185 EHgQPVESVLLFPSGGLLVSAG-GRYVKVWD 214 58778*****************.*******9 PP == domain 5 score: 25.7 bits; conditional E-value: 8.7e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 gq+l +l+ H + vt+l+ s++g+ l+sGs D++v+++ tr|B4DXK8|B4DXK8_HUMAN 219 GQLLVSLKNHhKTVTCLCLSSSGQRLLSGSLDRKVKVY 256 6788999999899***********************98 PP >> sp|Q9BVC4-3|LST8_HUMAN Isoform 2 of Target of rapamycin complex subunit LST8 OS=Homo sapiens GN=MLST8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.1 3.5e-06 0.00029 6 38 .] 14 47 .. 9 47 .. 0.82 2 ! 21.2 0.0 2.3e-05 0.0019 2 38 .] 54 90 .. 53 90 .. 0.96 3 ? 5.6 0.0 2 1.6e+02 12 38 .] 106 132 .. 93 132 .. 0.83 4 ! 24.1 0.0 2.8e-06 0.00023 15 37 .. 159 181 .. 142 182 .. 0.84 5 ! 14.3 0.3 0.0035 0.29 13 37 .. 207 231 .. 190 232 .. 0.85 6 ? 7.1 0.0 0.68 55 3 20 .. 238 256 .. 236 257 .. 0.83 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 3.5e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd sp|Q9BVC4-3|LST8_HUMAN 14 SYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 47 5555445688999********************9 PP == domain 2 score: 21.2 bits; conditional E-value: 2.3e-05 EEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtslafspdgawlasGsdDgtvriWd 38 qc+r++ ++++++ +p++a l+ G+ g ++iWd sp|Q9BVC4-3|LST8_HUMAN 54 QCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWD 90 8******9999*************************9 PP == domain 3 score: 5.6 bits; conditional E-value: 2 SEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 12 svtslafspdgawlasG.sdDgtvriWd 38 s+ts +pd +++a+ s g++++W+ sp|Q9BVC4-3|LST8_HUMAN 106 SITSAHIDPDASYMAAVnS-TGNCYVWN 132 389999*******997767.*******8 PP == domain 4 score: 24.1 bits; conditional E-value: 2.8e-06 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++fspd+++la++s D+t++iW sp|Q9BVC4-3|LST8_HUMAN 159 QCRFSPDSTLLATCSADQTCKIW 181 466******************** PP == domain 5 score: 14.3 bits; conditional E-value: 0.0035 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++afs d+++++++s D+ r+W sp|Q9BVC4-3|LST8_HUMAN 207 MWGCAFSGDSQYIVTASSDNLARLW 231 5899**********9988******* PP == domain 6 score: 7.1 bits; conditional E-value: 0.68 EEEEEESS.SSEEEEEEET CS WD40 3 clrtltGH.ssvtslafsp 20 r++ GH + v +laf++ sp|Q9BVC4-3|LST8_HUMAN 238 IKREYGGHqKAVVCLAFND 256 6789****99999**9976 PP >> sp|A2RRH5-2|WDR27_HUMAN Isoform 2 of WD repeat-containing protein 27 OS=Homo sapiens GN=WDR27 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 1.1 92 4 34 .. 64 97 .. 61 100 .. 0.66 2 ? 12.6 0.1 0.012 0.97 13 38 .] 419 444 .. 410 444 .. 0.82 3 ! 33.0 0.3 4.4e-09 3.6e-07 6 38 .] 453 486 .. 450 486 .. 0.92 4 ! 19.5 0.0 7.9e-05 0.0064 2 37 .. 647 685 .. 646 686 .. 0.88 5 ! 15.9 0.0 0.0011 0.088 5 36 .. 694 726 .. 690 727 .. 0.86 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 1.1 EEEEESS.SSEEEEE.EETTSSEEE.EEETTSEE CS WD40 4 lrtltGH.ssvtsla.fspdgawla.sGsdDgtv 34 l +l+GH +++t++a ++ +++l+ s+s D + sp|A2RRH5-2|WDR27_HUMAN 64 LLILRGHhQPITAMAfGNKVNPLLIcSASLDYVI 97 6789***999****76444444454144656555 PP == domain 2 score: 12.6 bits; conditional E-value: 0.012 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v+++++s dg+wla+G ++ + ++d sp|A2RRH5-2|WDR27_HUMAN 419 VCCIQYSGDGQWLACGLANHLLLVFD 444 9*************995588877776 PP == domain 3 score: 33.0 bits; conditional E-value: 4.4e-09 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH + v+++++s+d +wl+s+ +Dgt+r+W+ sp|A2RRH5-2|WDR27_HUMAN 453 VFSGHdGAVNAVCWSQDRRWLLSAARDGTLRMWS 486 799**666****************9********5 PP == domain 4 score: 19.5 bits; conditional E-value: 7.9e-05 EEEEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ss..vtslafspdgawlasGsdDgtvriW 37 +c r+++GH + +++afsp g++ a+G +D++ +++ sp|A2RRH5-2|WDR27_HUMAN 647 RCERHFEGHpTRgyPCGIAFSPCGRFAACGAEDRHAYVY 685 699******7446789***********9999****9887 PP == domain 5 score: 15.9 bits; conditional E-value: 0.0011 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvri 36 + l GH + vt++af+p+ + la+++ Dg++ + sp|A2RRH5-2|WDR27_HUMAN 694 HRLAGHtDTVTGVAFNPSAPQLATATLDGKLQL 726 6688**666****************99*99865 PP >> tr|H0YG45|H0YG45_HUMAN Autophagy-related protein 16-2 (Fragment) OS=Homo sapiens GN=ATG16L2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.0 4e-07 3.2e-05 5 38 .] 108 142 .. 105 142 .. 0.94 2 ? 10.9 0.0 0.043 3.5 5 37 .. 152 185 .. 149 186 .. 0.86 3 ! 15.9 0.0 0.0011 0.086 5 38 .] 194 228 .. 190 228 .. 0.81 4 ? 10.0 0.2 0.08 6.5 24 38 .] 253 267 .. 237 267 .. 0.81 5 ! 14.9 0.1 0.0022 0.18 6 38 .] 276 308 .. 271 308 .. 0.81 6 ! 14.4 0.2 0.0034 0.27 16 38 .] 332 354 .. 314 354 .. 0.85 7 ? 6.5 0.1 1 83 10 37 .. 368 396 .. 358 397 .] 0.81 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 4e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++H s v++++f p++++la+G+ D+ +++W+ tr|H0YG45|H0YG45_HUMAN 108 DVLDAHlSEVNAVRFGPNSSLLATGGADRLIHLWN 142 5799**999*************************8 PP == domain 2 score: 10.9 bits; conditional E-value: 0.043 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+G +s+ts++f+p+g ++++++++ +W tr|H0YG45|H0YG45_HUMAN 152 QTLEGAgGSITSVDFDPSGYQVLAATYNQAAQLW 185 689999888************9999878888888 PP == domain 3 score: 15.9 bits; conditional E-value: 0.0011 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl+GH++ vt+ +f + ++Gs+D+tv+ Wd tr|H0YG45|H0YG45_HUMAN 194 ETLSGHKDkVTAAKFKLTRHQAVTGSRDRTVKEWD 228 589***666****66555555889**********8 PP == domain 4 score: 10.0 bits; conditional E-value: 0.08 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 ++sG+ D+++r+Wd tr|H0YG45|H0YG45_HUMAN 253 IIISGHNDQKIRFWD 267 2579**********9 PP == domain 5 score: 14.9 bits; conditional E-value: 0.0022 EEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHssvtslafspdgawlasGsdDgtvriWd 38 ++ ++ vtsl+ s+d+ l+s+s+D+t+++ d tr|H0YG45|H0YG45_HUMAN 276 VIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVID 308 4444545***********************965 PP == domain 6 score: 14.4 bits; conditional E-value: 0.0034 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 fspd ++ ++Gs Dg ++iWd tr|H0YG45|H0YG45_HUMAN 332 AVFSPDRSYALAGSCDGALYIWD 354 44*******999*99*******9 PP == domain 7 score: 6.5 bits; conditional E-value: 1 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H v+++a++ +g+ ++s + ++v +W tr|H0YG45|H0YG45_HUMAN 368 HcAAVNAVAWCYSGSHMVSVDQGRKVVLW 396 6555****999999999888889999999 PP >> tr|Q5SRN1|Q5SRN1_HUMAN Pre-mRNA-processing factor 17 OS=Homo sapiens GN=CDC40 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.2 2.1e-06 0.00017 2 37 .. 279 316 .. 278 317 .. 0.93 2 ! 27.9 0.0 1.8e-07 1.4e-05 2 38 .] 323 360 .. 322 360 .. 0.94 3 ? 12.1 0.0 0.017 1.4 2 38 .] 365 404 .. 364 404 .. 0.79 4 ! 14.7 0.0 0.0026 0.21 2 37 .. 409 445 .. 408 446 .. 0.85 5 ? 9.4 0.0 0.12 10 16 36 .. 467 487 .. 456 488 .. 0.84 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 2.1e-06 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 +++++++GH ++v++++ f+ +g++l+s+s+D+++++W tr|Q5SRN1|Q5SRN1_HUMAN 279 KQIHVWSGHtKGVSAVRlFPLSGHLLLSCSMDCKIKLW 316 6799*****999*****999999999************ PP == domain 2 score: 27.9 bits; conditional E-value: 1.8e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +clrt+ GH + v++++f+ g+ ++s+ +D+ +++Wd tr|Q5SRN1|Q5SRN1_HUMAN 323 RCLRTFIGHsKAVRDICFNTAGTQFLSAAYDRYLKLWD 360 8********888************999999*******9 PP == domain 3 score: 12.1 bits; conditional E-value: 0.017 EEEEEEESSSSE.EEEEEETTSSE...EEEEETTSEEEEEE CS WD40 2 qclrtltGHssv.tslafspdgaw...lasGsdDgtvriWd 38 qc+ +t v ++++f+pd + +++G+ D+++ Wd tr|Q5SRN1|Q5SRN1_HUMAN 365 QCISRFTNR-KVpYCVKFNPDEDKqnlFVAGMSDKKIVQWD 404 566666522.3779************8778*66*******9 PP == domain 4 score: 14.7 bits; conditional E-value: 0.0026 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +++++ H + v+ + f ++++ ++s sdD+++r+W tr|Q5SRN1|Q5SRN1_HUMAN 409 EIVQEYDRHlGAVNTIVFVDENRRFVSTSDDKSLRVW 445 567889999999*99998888888888899******* PP == domain 5 score: 9.4 bits; conditional E-value: 0.12 EEEETTSSEEEEE.ETTSEEEE CS WD40 16 lafspdgawlasG.sdDgtvri 36 + sp+g+wla + s+D+ + i tr|Q5SRN1|Q5SRN1_HUMAN 467 VTLSPNGKWLA-CqSMDNQILI 487 557******97.7699***988 PP >> tr|H3BQA8|H3BQA8_HUMAN WD repeat-containing protein 61 (Fragment) OS=Homo sapiens GN=WDR61 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.0 1.9e-05 0.0016 11 38 .] 20 47 .. 9 47 .. 0.84 2 ! 39.3 0.0 4.3e-11 3.5e-09 1 38 [] 51 89 .. 51 89 .. 0.96 3 ! 32.1 1.5 8.6e-09 7e-07 5 38 .] 97 131 .. 93 131 .. 0.92 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 1.9e-05 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 +++ s+a+spdg++lasG Dg + i+d tr|H3BQA8|H3BQA8_HUMAN 20 KFILSIAYSPDGKYLASGAIDGIINIFD 47 5799**********************98 PP == domain 2 score: 39.3 bits; conditional E-value: 4.3e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l+tl+GH +++sl fspd+++l+++sdDg ++i+d tr|H3BQA8|H3BQA8_HUMAN 51 GKLLHTLEGHaMPIRSLTFSPDSQLLVTASDDGYIKIYD 89 689*******888*************************8 PP == domain 3 score: 32.1 bits; conditional E-value: 8.6e-09 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tl+GH s+v +af+pd + ++s+s D++v++Wd tr|H3BQA8|H3BQA8_HUMAN 97 GTLSGHaSWVLNVAFCPDDTHFVSSSSDKSVKVWD 131 79****999*************99877*******9 PP >> sp|Q9H7D7-2|WDR26_HUMAN Isoform 2 of WD repeat-containing protein 26 OS=Homo sapiens GN=WDR26 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 0.2 6.6e-07 5.4e-05 4 37 .. 332 366 .. 329 367 .. 0.94 2 ! 19.1 0.1 0.0001 0.0084 2 32 .. 376 408 .. 375 415 .. 0.82 3 ? 12.1 0.0 0.017 1.4 9 30 .. 428 450 .. 419 464 .. 0.81 4 ! 14.4 0.1 0.0033 0.27 13 37 .. 558 582 .. 544 583 .. 0.80 5 ! 26.5 0.0 5e-07 4.1e-05 3 37 .. 589 625 .. 587 625 .. 0.78 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 6.6e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++lt H + v+ ++fs dg+ la+Gs+D tv iW sp|Q9H7D7-2|WDR26_HUMAN 332 QQILTEHcNEVWFCKFSNDGTKLATGSKDTTVIIW 366 7899***888************************* PP == domain 2 score: 19.1 bits; conditional E-value: 0.0001 EEEEEEESS.SSEEEEEEETTSSEEEEEE.TTS CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs.dDg 32 ++l+tl+GH +v+ +a+spd ++l++++ dD+ sp|Q9H7D7-2|WDR26_HUMAN 376 KLLKTLEGHaYGVSYIAWSPDDNYLVACGpDDC 408 6899*****666**************9984444 PP == domain 3 score: 12.1 bits; conditional E-value: 0.017 SS.SSEEEEEEETTSSEEEEEET CS WD40 9 GH.ssvtslafspdgawlasGsd 30 H +s ts+a++pdg+ +++G+ sp|Q9H7D7-2|WDR26_HUMAN 428 SHeDSLTSVAWNPDGKRFVTGGQ 450 69888****************83 PP == domain 4 score: 14.4 bits; conditional E-value: 0.0033 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++s+ ++ +++asGs+D++v+iW sp|Q9H7D7-2|WDR26_HUMAN 558 IHSCFGGHNEDFIASGSEDHKVYIW 582 767778889999************* PP == domain 5 score: 26.5 bits; conditional E-value: 5e-07 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 ++ +ltGH v++++++p + +as+sdDgtvriW sp|Q9H7D7-2|WDR26_HUMAN 589 PIAELTGHtRTVNCVSWNPQIPSmMASASDDGTVRIW 625 57789***555****6655555555788********* PP >> tr|H0YAF8|H0YAF8_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.2 2.6 2.1e+02 31 38 .] 2 9 .. 1 9 [. 0.94 2 ! 37.1 0.2 2.2e-10 1.8e-08 3 38 .] 15 51 .. 13 51 .. 0.93 3 ! 18.9 0.6 0.00012 0.01 9 38 .] 64 101 .. 54 101 .. 0.78 4 ! 23.7 0.1 3.7e-06 0.0003 2 38 .] 106 141 .. 105 141 .. 0.87 5 ! 19.4 0.0 8.7e-05 0.0071 13 37 .. 167 191 .. 153 192 .. 0.89 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 2.6 TSEEEEEE CS WD40 31 DgtvriWd 38 Dgt+r+Wd tr|H0YAF8|H0YAF8_HUMAN 2 DGTLRLWD 9 9******9 PP == domain 2 score: 37.1 bits; conditional E-value: 2.2e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|H0YAF8|H0YAF8_HUMAN 15 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 51 678899******************************8 PP == domain 3 score: 18.9 bits; conditional E-value: 0.00012 SS.SSEEEEEEETTSSE..EEEEET.....TSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsd.....DgtvriWd 38 H +v++++fsp+++ ++s+++ Dg ++Wd tr|H0YAF8|H0YAF8_HUMAN 64 SHsEWVSCVRFSPNSSNpiIVSCGWdklvkDGQAMLWD 101 79666*************98899976677788888888 PP == domain 4 score: 23.7 bits; conditional E-value: 3.7e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++l+tl+G + +++l+fsp+ wl++++ ++++iWd tr|H0YAF8|H0YAF8_HUMAN 106 KHLYTLDGG-DiINALCFSPNRYWLCAAT-GPSIKIWD 141 778888887.448************9888.*******9 PP == domain 5 score: 19.4 bits; conditional E-value: 8.7e-05 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 tsla+s dg+ l++G D+ vr+W tr|H0YAF8|H0YAF8_HUMAN 167 CTSLAWSADGQTLFAGYTDNLVRVW 191 59**************88******* PP >> tr|B4DJF1|B4DJF1_HUMAN WD repeat-containing protein 86 OS=Homo sapiens GN=WDR86 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.1 1.9e-06 0.00015 3 38 .] 7 43 .. 5 43 .. 0.91 2 ! 13.6 0.0 0.0058 0.47 1 38 [] 47 83 .. 47 83 .. 0.83 3 ! 22.6 0.0 8.2e-06 0.00066 1 38 [] 87 123 .. 87 123 .. 0.75 4 ! 16.6 0.0 0.00067 0.054 2 37 .. 128 178 .. 127 179 .. 0.79 5 ! 17.9 0.5 0.00025 0.02 2 38 .] 184 221 .. 183 221 .. 0.91 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 1.9e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 lr++ H ++++ l+ spdg+ l++Gs+Dgt r+W+ tr|B4DJF1|B4DJF1_HUMAN 7 ALRVCADHrGGINWLSLSPDGQRLLTGSEDGTARLWS 43 5788889*999*************************5 PP == domain 2 score: 13.6 bits; conditional E-value: 0.0058 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gqc l GH s vt ++ ++ a+ ++s D+t+r Wd tr|B4DJF1|B4DJF1_HUMAN 47 GQCCALLQGHeSYVTFCQLEDEAAF--TCSADCTIRRWD 83 6888899***888*98867777777..7999*******9 PP == domain 3 score: 22.6 bits; conditional E-value: 8.2e-06 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 gqcl++++GH+s v+ + + ++ +s+s+D+t r+W+ tr|B4DJF1|B4DJF1_HUMAN 87 GQCLQVYRGHTSiVNRILVANNQL--FSSSYDRTARVWS 123 79********55479994433333..46888*******5 PP == domain 4 score: 16.6 bits; conditional E-value: 0.00067 EEEEEEESS.SSEEEEEEETTSSE................EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw................lasGsdDgtvriW 37 q r+++GH ++v la + +w l++Gs Dgt ++W tr|B4DJF1|B4DJF1_HUMAN 128 QMSREFRGHrNCVLTLA--YSAPWdlpstpcaeeaaagglLVTGSTDGTAKVW 178 67899****99999994..23444667777788888888789*********** PP == domain 5 score: 17.9 bits; conditional E-value: 0.00025 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +tl+GH + v +l + g+ ++Gs D t+r Wd tr|B4DJF1|B4DJF1_HUMAN 184 CCHQTLRGHtGAVLCLVLDTPGHTAFTGSTDATIRAWD 221 68899****777*****999999999***********9 PP >> sp|Q9H7D7|WDR26_HUMAN WD repeat-containing protein 26 OS=Homo sapiens GN=WDR26 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.2 6.8e-07 5.5e-05 4 37 .. 348 382 .. 345 383 .. 0.94 2 ! 19.1 0.1 0.00011 0.0086 2 32 .. 392 424 .. 391 431 .. 0.82 3 ? 12.1 0.1 0.018 1.4 9 30 .. 444 466 .. 435 509 .. 0.88 4 ! 14.3 0.1 0.0034 0.27 13 37 .. 574 598 .. 560 599 .. 0.80 5 ! 26.4 0.0 5.2e-07 4.2e-05 3 37 .. 605 641 .. 603 641 .. 0.78 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 6.8e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++lt H + v+ ++fs dg+ la+Gs+D tv iW sp|Q9H7D7|WDR26_HUMAN 348 QQILTEHcNEVWFCKFSNDGTKLATGSKDTTVIIW 382 7899***888************************* PP == domain 2 score: 19.1 bits; conditional E-value: 0.00011 EEEEEEESS.SSEEEEEEETTSSEEEEEE.TTS CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs.dDg 32 ++l+tl+GH +v+ +a+spd ++l++++ dD+ sp|Q9H7D7|WDR26_HUMAN 392 KLLKTLEGHaYGVSYIAWSPDDNYLVACGpDDC 424 6899*****666**************9984444 PP == domain 3 score: 12.1 bits; conditional E-value: 0.018 SS.SSEEEEEEETTSSEEEEEET CS WD40 9 GH.ssvtslafspdgawlasGsd 30 H +s ts+a++pdg+ +++G+ sp|Q9H7D7|WDR26_HUMAN 444 SHeDSLTSVAWNPDGKRFVTGGQ 466 69888***************983 PP == domain 4 score: 14.3 bits; conditional E-value: 0.0034 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++s+ ++ +++asGs+D++v+iW sp|Q9H7D7|WDR26_HUMAN 574 IHSCFGGHNEDFIASGSEDHKVYIW 598 767778889999************* PP == domain 5 score: 26.4 bits; conditional E-value: 5.2e-07 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 ++ +ltGH v++++++p + +as+sdDgtvriW sp|Q9H7D7|WDR26_HUMAN 605 PIAELTGHtRTVNCVSWNPQIPSmMASASDDGTVRIW 641 57789***555****6655555555788********* PP >> tr|H0YF72|H0YF72_HUMAN Autophagy-related protein 16-2 (Fragment) OS=Homo sapiens GN=ATG16L2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.0 4.7e-07 3.8e-05 5 38 .] 161 195 .. 158 195 .. 0.94 2 ? 10.6 0.0 0.05 4.1 5 37 .. 205 238 .. 202 239 .. 0.86 3 ! 15.7 0.0 0.0012 0.1 5 38 .] 247 281 .. 243 281 .. 0.81 4 ? 9.8 0.2 0.093 7.5 24 38 .] 306 320 .. 290 320 .. 0.81 5 ! 14.7 0.1 0.0026 0.21 7 38 .] 330 361 .. 324 361 .. 0.81 6 ! 14.1 0.2 0.0039 0.32 16 38 .] 385 407 .. 367 407 .. 0.85 7 ? 6.3 0.1 1.2 98 10 37 .. 421 449 .. 411 450 .] 0.81 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 4.7e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++H s v++++f p++++la+G+ D+ +++W+ tr|H0YF72|H0YF72_HUMAN 161 DVLDAHlSEVNAVRFGPNSSLLATGGADRLIHLWN 195 5799**999*************************8 PP == domain 2 score: 10.6 bits; conditional E-value: 0.05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+G +s+ts++f+p+g ++++++++ +W tr|H0YF72|H0YF72_HUMAN 205 QTLEGAgGSITSVDFDPSGYQVLAATYNQAAQLW 238 689999888************9999878888888 PP == domain 3 score: 15.7 bits; conditional E-value: 0.0012 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl+GH++ vt+ +f + ++Gs+D+tv+ Wd tr|H0YF72|H0YF72_HUMAN 247 ETLSGHKDkVTAAKFKLTRHQAVTGSRDRTVKEWD 281 589***666****66555555889**********8 PP == domain 4 score: 9.8 bits; conditional E-value: 0.093 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 ++sG+ D+++r+Wd tr|H0YF72|H0YF72_HUMAN 306 IIISGHNDQKIRFWD 320 2579**********9 PP == domain 5 score: 14.7 bits; conditional E-value: 0.0026 EESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtslafspdgawlasGsdDgtvriWd 38 + ++ vtsl+ s+d+ l+s+s+D+t+++ d tr|H0YF72|H0YF72_HUMAN 330 IPVQGRVTSLSLSHDQLHLLSCSRDNTLKVID 361 444545***********************965 PP == domain 6 score: 14.1 bits; conditional E-value: 0.0039 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 fspd ++ ++Gs Dg ++iWd tr|H0YF72|H0YF72_HUMAN 385 AVFSPDRSYALAGSCDGALYIWD 407 44*******999*99*******9 PP == domain 7 score: 6.3 bits; conditional E-value: 1.2 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H v+++a++ +g+ ++s + ++v +W tr|H0YF72|H0YF72_HUMAN 421 HcAAVNAVAWCYSGSHMVSVDQGRKVVLW 449 6555****999999999888889999999 PP >> sp|O75037-3|KI21B_HUMAN Isoform 3 of Kinesin-like protein KIF21B OS=Homo sapiens GN=KIF21B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 8.9e-05 0.0072 2 38 .] 1286 1321 .. 1285 1321 .. 0.92 2 ? 9.4 0.1 0.12 9.8 2 38 .] 1326 1362 .. 1325 1362 .. 0.92 3 ? 10.0 0.0 0.083 6.7 10 37 .. 1400 1425 .. 1388 1426 .. 0.87 4 ! 16.8 0.0 0.00059 0.047 2 37 .. 1431 1470 .. 1430 1471 .. 0.91 5 ? 7.5 0.0 0.51 41 9 38 .] 1489 1517 .. 1480 1517 .. 0.79 6 ? 12.4 0.0 0.014 1.2 5 38 .] 1526 1560 .. 1522 1560 .. 0.89 7 ! 14.7 0.1 0.0027 0.22 3 38 .] 1566 1600 .. 1564 1600 .. 0.79 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 8.9e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+ +GH +++ +l + +l++Gs+D+++++W+ sp|O75037-3|KI21B_HUMAN 1286 QCVSMAEGHtKPILCL--DATDELLFTGSKDRSCKMWN 1321 6778889**999****..999999*************8 PP == domain 2 score: 9.4 bits; conditional E-value: 0.12 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q + l+GH ++v s+++++++ +++s s +++Wd sp|O75037-3|KI21B_HUMAN 1326 QEIAALKGHpNNVVSIKYCSHSGLVFSVS-TSYIKVWD 1362 678889***99999**********9999*.*******9 PP == domain 3 score: 10.0 bits; conditional E-value: 0.083 SSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriW 37 H ++ +a sp+g++l ++s + vriW sp|O75037-3|KI21B_HUMAN 1400 H-QINQIALSPSGTMLYAAS-GNAVRIW 1425 4.59****************.******* PP == domain 4 score: 16.8 bits; conditional E-value: 0.00059 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriW 37 q++++ltGH ++v +l + + ++++++Gs+D+ v+++ sp|O75037-3|KI21B_HUMAN 1431 QPVGKLTGHiGPVMCLTvtqTASQHDLVVTGSKDHYVKMF 1470 899*************998888888889*********986 PP == domain 5 score: 7.5 bits; conditional E-value: 0.51 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l g+ l+sGs+D+ ++ Wd sp|O75037-3|KI21B_HUMAN 1489 PHyDGIECL--AIQGDILFSGSRDNGIKKWD 1517 577779999..44788899***********9 PP == domain 6 score: 12.4 bits; conditional E-value: 0.014 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +H ++v++laf p ++l+s+++ g +++W+ sp|O75037-3|KI21B_HUMAN 1526 QIPNAHkDWVCALAFIPGRPMLLSACRAGVIKVWN 1560 66789*666*************************8 PP == domain 7 score: 14.7 bits; conditional E-value: 0.0027 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++++GH s++++++++ + + +++s D tv++W+ sp|O75037-3|KI21B_HUMAN 1566 PIGEIKGHdSPINAICTNAKHIF-TASS-DLTVKFWS 1600 78899***888****77666666.4456.*******5 PP >> sp|O75037-4|KI21B_HUMAN Isoform 4 of Kinesin-like protein KIF21B OS=Homo sapiens GN=KIF21B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 9e-05 0.0073 2 38 .] 1299 1334 .. 1298 1334 .. 0.92 2 ? 9.4 0.1 0.12 9.9 2 38 .] 1339 1375 .. 1338 1375 .. 0.92 3 ? 9.9 0.0 0.083 6.7 10 37 .. 1413 1438 .. 1401 1439 .. 0.87 4 ! 16.7 0.0 0.00059 0.048 2 37 .. 1444 1483 .. 1443 1484 .. 0.91 5 ? 7.4 0.0 0.51 42 9 38 .] 1502 1530 .. 1493 1530 .. 0.79 6 ? 12.4 0.0 0.014 1.2 5 38 .] 1539 1573 .. 1535 1573 .. 0.89 7 ! 14.6 0.1 0.0027 0.22 3 38 .] 1579 1613 .. 1577 1613 .. 0.79 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 9e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 qc+ +GH +++ +l + +l++Gs+D+++++W+ sp|O75037-4|KI21B_HUMAN 1299 QCVSMAEGHtKPILCL--DATDELLFTGSKDRSCKMWN 1334 6778889**999****..999999*************8 PP == domain 2 score: 9.4 bits; conditional E-value: 0.12 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q + l+GH ++v s+++++++ +++s s +++Wd sp|O75037-4|KI21B_HUMAN 1339 QEIAALKGHpNNVVSIKYCSHSGLVFSVS-TSYIKVWD 1375 678889***99999**********9999*.*******9 PP == domain 3 score: 9.9 bits; conditional E-value: 0.083 SSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriW 37 H ++ +a sp+g++l ++s + vriW sp|O75037-4|KI21B_HUMAN 1413 H-QINQIALSPSGTMLYAAS-GNAVRIW 1438 4.59****************.******* PP == domain 4 score: 16.7 bits; conditional E-value: 0.00059 EEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgawlasGsdDgtvriW 37 q++++ltGH ++v +l + + ++++++Gs+D+ v+++ sp|O75037-4|KI21B_HUMAN 1444 QPVGKLTGHiGPVMCLTvtqTASQHDLVVTGSKDHYVKMF 1483 899*************998888888889*********986 PP == domain 5 score: 7.4 bits; conditional E-value: 0.51 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ +l g+ l+sGs+D+ ++ Wd sp|O75037-4|KI21B_HUMAN 1502 PHyDGIECL--AIQGDILFSGSRDNGIKKWD 1530 577779999..44788899***********9 PP == domain 6 score: 12.4 bits; conditional E-value: 0.014 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +H ++v++laf p ++l+s+++ g +++W+ sp|O75037-4|KI21B_HUMAN 1539 QIPNAHkDWVCALAFIPGRPMLLSACRAGVIKVWN 1573 66789*666*************************8 PP == domain 7 score: 14.6 bits; conditional E-value: 0.0027 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++++GH s++++++++ + + +++s D tv++W+ sp|O75037-4|KI21B_HUMAN 1579 PIGEIKGHdSPINAICTNAKHIF-TASS-DLTVKFWS 1613 78899***888****77666666.4456.*******5 PP >> sp|P57737-4|CORO7_HUMAN Isoform 4 of Coronin-7 OS=Homo sapiens GN=CORO7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.49 40 27 37 .. 77 87 .. 58 88 .. 0.82 2 ? 5.0 0.0 3.1 2.5e+02 16 38 .] 114 136 .. 105 136 .. 0.76 3 ! 14.8 0.0 0.0024 0.2 2 38 .] 141 178 .. 140 178 .. 0.88 4 ? 10.8 0.0 0.046 3.7 12 37 .. 528 554 .. 520 555 .. 0.85 5 ! 22.9 0.0 6.6e-06 0.00054 4 38 .] 569 605 .. 566 605 .. 0.85 6 ! 24.0 0.0 3.1e-06 0.00025 7 37 .. 615 646 .. 611 647 .. 0.90 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.49 EEETTSEEEEE CS WD40 27 sGsdDgtvriW 37 sGs D+tv++W sp|P57737-4|CORO7_HUMAN 77 SGSADRTVKLW 87 7999******* PP == domain 2 score: 5.0 bits; conditional E-value: 3.1 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 l+f+p ++ ++ + tv++Wd sp|P57737-4|CORO7_HUMAN 114 LQFHPTSDGILVSAAGTTVKVWD 136 567888888654444*******9 PP == domain 3 score: 14.8 bits; conditional E-value: 0.0024 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 q+l++l +H++ v s +s+dga++ ++++D+ +ri+d sp|P57737-4|CORO7_HUMAN 141 QPLTELAAHGDlVQSAVWSRDGALVGTACKDKQLRIFD 178 89999****77899999*******856789******98 PP == domain 4 score: 10.8 bits; conditional E-value: 0.046 SEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriW 37 vt+la++p + la +++D +r+W sp|P57737-4|CORO7_HUMAN 528 AVTDLAWDPFDPHrLAVAGEDARIRLW 554 49***********9887888******* PP == domain 5 score: 22.9 bits; conditional E-value: 6.6e-06 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ltGH ++sl+f+p a ++ s+s+D tvriWd sp|P57737-4|CORO7_HUMAN 569 ETVLTGHtEKICSLRFHPLAANVLaSSSYDLTVRIWD 605 5789***666************7527789*******9 PP == domain 6 score: 24.0 bits; conditional E-value: 3.1e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH + + sla+spdg+ la+ ++Dg vr++ sp|P57737-4|CORO7_HUMAN 615 LQGHqDQIFSLAWSPDGQQLATVCKDGRVRVY 646 78**666***************9*******98 PP >> sp|Q6IA86-4|ELP2_HUMAN Isoform 4 of Elongator complex protein 2 OS=Homo sapiens GN=ELP2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.3 0.0077 0.62 4 37 .. 51 90 .. 48 91 .. 0.71 2 ? 8.5 0.0 0.23 19 6 38 .] 102 143 .. 98 143 .. 0.69 3 ? 7.5 0.0 0.5 40 4 37 .. 152 190 .. 150 190 .. 0.73 4 ! 18.7 0.3 0.00014 0.011 2 38 .] 198 237 .. 197 237 .. 0.85 5 ? 11.1 0.0 0.035 2.8 5 37 .. 277 319 .. 274 319 .. 0.80 6 ! 16.4 0.0 0.00075 0.061 4 36 .. 381 414 .. 378 416 .. 0.84 7 ? 5.4 0.0 2.3 1.9e+02 4 29 .. 560 586 .. 557 600 .. 0.83 8 ! 16.9 0.0 0.00054 0.043 2 38 .] 605 642 .. 604 642 .. 0.86 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 0.0077 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 ++ l GH v++++ sp+ ++ sG+ D+ v W sp|Q6IA86-4|ELP2_HUMAN 51 VTNLNGHtARVNCIQwickqdGSPSTELV-SGGSDNQVIHW 90 56789**6669999555555566666665.6766**99988 PP == domain 2 score: 8.5 bits; conditional E-value: 0.23 EEESS.SSEEEEE.......EETTSSE...EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgaw...lasGsdDgtvriWd 38 +l GH ++v+++ +p + ++s+ D vr+W+ sp|Q6IA86-4|ELP2_HUMAN 102 HLQGHeGPVYAVHavyqrrtSDPA--LctlIVSAAADSAVRLWS 143 789**8888888655566443333..2555567777*******5 PP == domain 3 score: 7.5 bits; conditional E-value: 0.5 EEEEE.SS.SSE.EEEEEETTSSE..EEEEETTSEEEEE CS WD40 4 lrtlt.GH.ssv.tslafspdgaw..lasGsdDgtvriW 37 l+tl G + +l+f p+ + la+G dD+ ++i+ sp|Q6IA86-4|ELP2_HUMAN 152 LQTLNfGNgFALaLCLSFLPNTDVpiLACGNDDCRIHIF 190 55655455333446999999999998888989****995 PP == domain 4 score: 18.7 bits; conditional E-value: 0.00014 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 q++ +l GH ++++++ w las+s D+ +riW+ sp|Q6IA86-4|ELP2_HUMAN 198 QKVLSLCGHeDWIRGV------EWaafgrdlfLASCSQDCLIRIWK 237 6677889**888****......887777778889***********6 PP == domain 5 score: 11.1 bits; conditional E-value: 0.035 EEEESS.SSEEEEE....EETTSSE.....EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla....fspdgaw.....lasGsdDgtvriW 37 ++l GH ++v+++ f +dg + l+s+s+D+t +W sp|Q6IA86-4|ELP2_HUMAN 277 TVLAGHeNWVNAVHwqpvFYKDGVLqqpvrLLSASMDKTMILW 319 5688**999****555555555555*****889999****999 PP == domain 6 score: 16.4 bits; conditional E-value: 0.00075 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++GH ++v +l ++p+g ++++ + D+t r+ sp|Q6IA86-4|ELP2_HUMAN 381 EIVISGHfDGVQDLVWDPEGEFIITVGTDQTTRL 414 56789**777************997666***998 PP == domain 7 score: 5.4 bits; conditional E-value: 2.3 EEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGs 29 +++l GH+ + ++ ++++++las++ sp|Q6IA86-4|ELP2_HUMAN 560 VQKLYGHGYeIFCVTCNSSKTLLASAC 586 67889**446*************9886 PP == domain 8 score: 16.9 bits; conditional E-value: 0.00054 EEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 ++++ l H s vt +afsp+ ++l++ s+D+t +W+ sp|Q6IA86-4|ELP2_HUMAN 605 KQVQNLVFH-SltVTQMAFSPNEKFLLAVSRDRTWSLWK 642 667778889.446**************99*********6 PP >> sp|P54198|HIRA_HUMAN Protein HIRA OS=Homo sapiens GN=HIRA PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.2 0.0021 0.17 9 38 .] 10 44 .. 4 44 .. 0.85 2 ! 25.5 0.1 1e-06 8.3e-05 9 38 .] 68 98 .. 61 98 .. 0.90 3 ! 34.0 3.6 2.1e-09 1.7e-07 1 38 [] 121 159 .. 121 159 .. 0.95 4 ! 22.2 0.0 1.1e-05 0.00092 3 37 .. 166 201 .. 164 202 .. 0.89 5 ? 10.3 0.1 0.063 5.1 9 29 .. 221 241 .. 213 246 .. 0.79 6 ? 5.0 0.5 3 2.4e+02 7 37 .. 264 312 .. 258 312 .. 0.57 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 0.0021 SS..SSEEEEEEETTSSEEEEEE...TTSEEEEEE CS WD40 9 GH..ssvtslafspdgawlasGs...dDgtvriWd 38 H +++ s++ +pdg+ +a+G+ d g+v iW+ sp|P54198|HIRA_HUMAN 10 NHngKPIFSVDIHPDGTKFATGGqgqDSGKVVIWN 44 686566****************86677*******8 PP == domain 2 score: 25.5 bits; conditional E-value: 1e-06 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +v+++++s +g +lasG+dD+ +++W+ sp|P54198|HIRA_HUMAN 68 NHlACVNCVRWSNSGMYLASGGDDKLIMVWK 98 68888*************************6 PP == domain 3 score: 34.0 bits; conditional E-value: 2.1e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++c+ +l+ H ++v ++a+sp+ awlas+s D+tv iW+ sp|P54198|HIRA_HUMAN 121 WRCVSILRNHsGDVMDVAWSPHDAWLASCSVDNTVVIWN 159 68********777*************************8 PP == domain 4 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriW 37 l tl+GHs+ v +l ++p g+++as dD+++++W sp|P54198|HIRA_HUMAN 166 ILATLRGHSGlVKGLTWDPVGKYIASQADDRSLKVW 201 5789****7789***********986588******* PP == domain 5 score: 10.3 bits; conditional E-value: 0.063 SSSSEEEEEEETTSSEEEEEE CS WD40 9 GHssvtslafspdgawlasGs 29 G ++v l++spdg++l+s++ sp|P54198|HIRA_HUMAN 221 GTTHVLRLSWSPDGHYLVSAH 241 3344**************986 PP == domain 6 score: 5.0 bits; conditional E-value: 3 EESS.SSEEEEE...............EETTSSE..EEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla...............fspdgaw..lasGsdDgtvriW 37 + GH + vt ++ p+ ++ a Gs+D+++ +W sp|P54198|HIRA_HUMAN 264 FVGHrKAVTVVKfnpkifkkkqkngssAKPSCPYccCAVGSKDRSLSVW 312 5677666766655555555544444442222223324569********9 PP >> sp|Q9UM11-2|FZR_HUMAN Isoform 2 of Fizzy-related protein homolog OS=Homo sapiens GN=FZR1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.8 0.011 0.92 10 38 .] 230 257 .. 206 257 .. 0.86 2 ? 9.2 0.0 0.14 12 1 34 [. 261 293 .. 261 297 .. 0.84 3 ! 27.2 0.0 3e-07 2.4e-05 5 38 .] 307 341 .. 303 341 .. 0.92 4 ! 19.9 0.0 6e-05 0.0049 3 38 .] 347 386 .. 345 386 .. 0.84 5 ? 5.1 0.1 2.8 2.2e+02 9 38 .] 399 429 .. 387 429 .. 0.71 6 ! 18.3 0.0 0.0002 0.016 4 38 .] 436 471 .. 433 471 .. 0.88 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.011 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 svts+ +s g+++a G+ +g v iWd sp|Q9UM11-2|FZR_HUMAN 230 D-SVTSVGWSERGNLVAVGTHKGFVQIWD 257 3.699999***********88*******9 PP == domain 2 score: 9.2 bits; conditional E-value: 0.14 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtv 34 g++l l+GH v +l aw l+sGs+D+ + sp|Q9UM11-2|FZR_HUMAN 261 GKKLSMLEGHtARVGAL------AWnaeqLSSGSRDRMI 293 5788999***666****......77777799*****988 PP == domain 3 score: 27.2 bits; conditional E-value: 3e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r l GH + v++l++s d+++lasG+ D+++ +W+ sp|Q9UM11-2|FZR_HUMAN 307 RRLQGHrQEVCGLKWSTDHQLLASGGNDNKLLVWN 341 6799**999*************************8 PP == domain 4 score: 19.9 bits; conditional E-value: 6e-05 EEEEEESS.SSEEEEEEETTSSEEE.EEE..TTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla.sGs..dDgtvriWd 38 +++ +t H v ++a+sp+++ l+ sG+ D+ +r+W+ sp|Q9UM11-2|FZR_HUMAN 347 PVQQYTEHlAAVKAIAWSPHQHGLLaSGGgtADRCIRFWN 386 78999***999************752664447*******8 PP == domain 5 score: 5.1 bits; conditional E-value: 2.8 SSSSEEEEEEETTSSEEEEE...ETTSEEEEEE CS WD40 9 GHssvtslafspdgawlasG...sdDgtvriWd 38 G v+ la+s++ + l+s s + + +W+ sp|Q9UM11-2|FZR_HUMAN 399 GS-QVCNLAWSKHANELVSThgyS-QNQILVWK 429 33.5999*9*********953233.99999995 PP == domain 6 score: 18.3 bits; conditional E-value: 0.0002 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + +ltGHs v la spdg +++G D t+r+W+ sp|Q9UM11-2|FZR_HUMAN 436 VAKLTGHSYrVLYLAMSPDGEAIVTGAGDETLRFWN 471 6789***558****************66*******8 PP >> sp|Q9UM11|FZR_HUMAN Fizzy-related protein homolog OS=Homo sapiens GN=FZR1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.8 0.011 0.93 10 38 .] 230 257 .. 206 257 .. 0.86 2 ? 9.2 0.0 0.15 12 1 34 [. 261 293 .. 261 297 .. 0.84 3 ! 27.2 0.0 3e-07 2.4e-05 5 38 .] 307 341 .. 303 341 .. 0.92 4 ! 19.9 0.0 6e-05 0.0049 3 38 .] 347 386 .. 345 386 .. 0.84 5 ? 5.1 0.1 2.8 2.3e+02 9 38 .] 399 429 .. 387 429 .. 0.71 6 ! 18.2 0.0 0.0002 0.016 4 38 .] 436 471 .. 433 471 .. 0.88 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.011 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 svts+ +s g+++a G+ +g v iWd sp|Q9UM11|FZR_HUMAN 230 D-SVTSVGWSERGNLVAVGTHKGFVQIWD 257 3.699999***********88*******9 PP == domain 2 score: 9.2 bits; conditional E-value: 0.15 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtv 34 g++l l+GH v +l aw l+sGs+D+ + sp|Q9UM11|FZR_HUMAN 261 GKKLSMLEGHtARVGAL------AWnaeqLSSGSRDRMI 293 5788999***666****......77777799*****988 PP == domain 3 score: 27.2 bits; conditional E-value: 3e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r l GH + v++l++s d+++lasG+ D+++ +W+ sp|Q9UM11|FZR_HUMAN 307 RRLQGHrQEVCGLKWSTDHQLLASGGNDNKLLVWN 341 6799**999*************************8 PP == domain 4 score: 19.9 bits; conditional E-value: 6e-05 EEEEEESS.SSEEEEEEETTSSEEE.EEE..TTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla.sGs..dDgtvriWd 38 +++ +t H v ++a+sp+++ l+ sG+ D+ +r+W+ sp|Q9UM11|FZR_HUMAN 347 PVQQYTEHlAAVKAIAWSPHQHGLLaSGGgtADRCIRFWN 386 78999***999************752664447*******8 PP == domain 5 score: 5.1 bits; conditional E-value: 2.8 SSSSEEEEEEETTSSEEEEE...ETTSEEEEEE CS WD40 9 GHssvtslafspdgawlasG...sdDgtvriWd 38 G v+ la+s++ + l+s s + + +W+ sp|Q9UM11|FZR_HUMAN 399 GS-QVCNLAWSKHANELVSThgyS-QNQILVWK 429 33.5999*9*********953233.99999995 PP == domain 6 score: 18.2 bits; conditional E-value: 0.0002 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + +ltGHs v la spdg +++G D t+r+W+ sp|Q9UM11|FZR_HUMAN 436 VAKLTGHSYrVLYLAMSPDGEAIVTGAGDETLRFWN 471 6789***558****************66*******8 PP >> sp|Q8NAA4-2|A16L2_HUMAN Isoform 2 of Autophagy-related protein 16-2 OS=Homo sapiens GN=ATG16L2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.0 5.5e-07 4.5e-05 5 38 .] 224 258 .. 221 258 .. 0.94 2 ? 10.4 0.0 0.06 4.8 5 37 .. 268 301 .. 265 302 .. 0.86 3 ! 15.5 0.0 0.0015 0.12 5 38 .] 310 344 .. 306 344 .. 0.81 4 ? 9.6 0.2 0.11 8.8 24 38 .] 369 383 .. 353 383 .. 0.81 5 ! 14.5 0.1 0.0031 0.25 7 38 .] 393 424 .. 387 424 .. 0.81 6 ! 13.9 0.2 0.0046 0.38 16 38 .] 448 470 .. 430 470 .. 0.85 7 ? 6.0 0.1 1.4 1.2e+02 10 37 .. 484 512 .. 474 513 .] 0.81 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 5.5e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++H s v++++f p++++la+G+ D+ +++W+ sp|Q8NAA4-2|A16L2_HUMAN 224 DVLDAHlSEVNAVRFGPNSSLLATGGADRLIHLWN 258 5799**999*************************8 PP == domain 2 score: 10.4 bits; conditional E-value: 0.06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+G +s+ts++f+p+g ++++++++ +W sp|Q8NAA4-2|A16L2_HUMAN 268 QTLEGAgGSITSVDFDPSGYQVLAATYNQAAQLW 301 689999888************9999878888888 PP == domain 3 score: 15.5 bits; conditional E-value: 0.0015 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl+GH++ vt+ +f + ++Gs+D+tv+ Wd sp|Q8NAA4-2|A16L2_HUMAN 310 ETLSGHKDkVTAAKFKLTRHQAVTGSRDRTVKEWD 344 589***666****66555555889**********8 PP == domain 4 score: 9.6 bits; conditional E-value: 0.11 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 ++sG+ D+++r+Wd sp|Q8NAA4-2|A16L2_HUMAN 369 IIISGHNDQKIRFWD 383 2579**********9 PP == domain 5 score: 14.5 bits; conditional E-value: 0.0031 EESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtslafspdgawlasGsdDgtvriWd 38 + ++ vtsl+ s+d+ l+s+s+D+t+++ d sp|Q8NAA4-2|A16L2_HUMAN 393 IPVQGRVTSLSLSHDQLHLLSCSRDNTLKVID 424 444545***********************965 PP == domain 6 score: 13.9 bits; conditional E-value: 0.0046 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 fspd ++ ++Gs Dg ++iWd sp|Q8NAA4-2|A16L2_HUMAN 448 AVFSPDRSYALAGSCDGALYIWD 470 44*******999*99*******9 PP == domain 7 score: 6.0 bits; conditional E-value: 1.4 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H v+++a++ +g+ ++s + ++v +W sp|Q8NAA4-2|A16L2_HUMAN 484 HcAAVNAVAWCYSGSHMVSVDQGRKVVLW 512 6555****999999999888889999999 PP >> tr|E9PD14|E9PD14_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.0 5.1e-05 0.0041 4 38 .] 8 44 .. 5 44 .. 0.87 2 ! 37.3 0.6 1.9e-10 1.5e-08 3 38 .] 55 91 .. 53 91 .. 0.93 3 ! 37.7 0.2 1.4e-10 1.1e-08 3 38 .] 97 133 .. 95 133 .. 0.93 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 5.1e-05 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s+s+D+t+ +W+ tr|E9PD14|E9PD14_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRDKTIIMWK 44 5799***666****99888888899***********6 PP == domain 2 score: 37.3 bits; conditional E-value: 1.9e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|E9PD14|E9PD14_HUMAN 55 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 91 7899****667************99***********9 PP == domain 3 score: 37.7 bits; conditional E-value: 1.4e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|E9PD14|E9PD14_HUMAN 97 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133 678899******************************8 PP >> tr|D6RAU2|D6RAU2_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.0 4.8e-05 0.0038 4 38 .] 8 44 .. 5 44 .. 0.87 2 ! 37.4 0.6 1.8e-10 1.4e-08 3 38 .] 55 91 .. 53 91 .. 0.93 3 ! 37.8 0.2 1.3e-10 1.1e-08 3 38 .] 97 133 .. 95 133 .. 0.93 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 4.8e-05 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s+s+D+t+ +W+ tr|D6RAU2|D6RAU2_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRDKTIIMWK 44 5799***666****99888888899***********6 PP == domain 2 score: 37.4 bits; conditional E-value: 1.8e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6RAU2|D6RAU2_HUMAN 55 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 91 7899****667************99***********9 PP == domain 3 score: 37.8 bits; conditional E-value: 1.3e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|D6RAU2|D6RAU2_HUMAN 97 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133 678899******************************8 PP >> tr|B0AZV0|B0AZV0_HUMAN Serine-threonine kinase receptor-associated protein OS=Homo sapiens GN=STRAP PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 5.5e-05 0.0045 9 38 .] 4 34 .. 1 34 [. 0.91 2 ! 19.6 0.0 7.6e-05 0.0061 6 38 .] 44 76 .. 40 76 .. 0.75 3 ? 9.0 0.0 0.17 14 3 35 .. 122 154 .. 120 157 .. 0.83 4 ! 40.1 0.0 2.5e-11 2e-09 2 37 .. 162 198 .. 161 199 .. 0.93 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 5.5e-05 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 +H++ v ++f +d+++l++G+ D+ +ri+d tr|B0AZV0|B0AZV0_HUMAN 4 AHKHiVKTVDFTQDSNYLLTGGQDKLLRIYD 34 798856************************8 PP == domain 2 score: 19.6 bits; conditional E-value: 7.6e-05 EEESS.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssv.tslafspdgawlasGsdDgtvriWd 38 +++GH s++ +l ++++ + ++s++ D+tvr+Wd tr|B0AZV0|B0AZV0_HUMAN 44 EISGHtSGIkKAL-WCSEDKQILSAD-DKTVRLWD 76 679**888*6666.555555556777.*******9 PP == domain 3 score: 9.0 bits; conditional E-value: 0.17 EEEEEESSSSEEEEEEETTSSEEEEEETTSEEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtvr 35 +++++++ ++s + +p++ +l++G++D +++ tr|B0AZV0|B0AZV0_HUMAN 122 PIKSFEAPATINSASLHPEKEFLVAGGEDFKLY 154 6777877766*****************998775 PP == domain 4 score: 40.1 bits; conditional E-value: 2.5e-11 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + l +++GH +++++++fspdg + asGs+Dgt+r+W tr|B0AZV0|B0AZV0_HUMAN 162 EELESYKGHfGPIHCVRFSPDGELYASGSEDGTLRLW 198 67889****888************************* PP >> tr|E9PF19|E9PF19_HUMAN Transducin beta-like protein 2 OS=Homo sapiens GN=TBL2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.9 0.1 1.1e-09 8.9e-08 7 38 .] 50 82 .. 42 82 .. 0.90 2 ? 10.0 0.0 0.082 6.6 10 38 .] 151 180 .. 143 180 .. 0.79 3 ? 8.7 0.0 0.21 17 14 37 .. 197 220 .. 182 221 .. 0.87 4 ! 25.5 0.2 1e-06 8.4e-05 6 38 .] 238 271 .. 233 271 .. 0.91 5 ? 11.9 0.0 0.02 1.6 10 37 .. 336 363 .. 329 364 .. 0.85 Alignments for each domain: == domain 1 score: 34.9 bits; conditional E-value: 1.1e-09 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+ H +++++++fs++g++la++ dD+t+riW+ tr|E9PF19|E9PF19_HUMAN 50 LKSHsGNISCMDFSSNGKYLATCADDRTIRIWS 82 6789555*************************5 PP == domain 2 score: 10.0 bits; conditional E-value: 0.082 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +v ++ g++++++s D tv iW+ tr|E9PF19|E9PF19_HUMAN 151 HkAPVIDIGIANTGKFIMTASSDTTVLIWS 180 64445566678899***99877*******5 PP == domain 3 score: 8.7 bits; conditional E-value: 0.21 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 t+ a+sp g+++as++ + v++W tr|E9PF19|E9PF19_HUMAN 197 THAAVSPCGRFVASCGFTPDVKVW 220 56679*********999******* PP == domain 4 score: 25.5 bits; conditional E-value: 1e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH v+s+afs d++ +as s+Dgt ++Wd tr|E9PF19|E9PF19_HUMAN 238 ELKGHsAAVHSFAFSNDSRRMASVSKDGTWKLWD 271 589**555**************99*********9 PP == domain 5 score: 11.9 bits; conditional E-value: 0.02 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ++ l+f+ g++las++ D+ vr++ tr|E9PF19|E9PF19_HUMAN 336 HgECIANLSFDITGRFLASCG-DRAVRLF 363 644588899************.*****96 PP >> sp|Q8N9V3-2|WSDU1_HUMAN Isoform 2 of WD repeat, SAM and U-box domain-containing protein 1 OS=Homo sapiens GN=WDSUB1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.2 7.4e-05 0.006 2 37 .. 3 37 .. 2 38 .. 0.82 2 ! 27.8 0.4 1.8e-07 1.5e-05 7 38 .] 50 82 .. 44 82 .. 0.87 3 ! 22.7 0.0 7.8e-06 0.00063 12 38 .] 99 125 .. 86 125 .. 0.82 4 ! 13.1 0.3 0.0081 0.66 14 38 .] 143 167 .. 130 167 .. 0.86 5 ! 16.5 0.1 0.00071 0.057 3 37 .. 172 217 .. 170 217 .. 0.83 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 7.4e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++tl H ++v+++afs ++la++s D+t+r++ sp|Q8N9V3-2|WSDU1_HUMAN 3 KLIHTLADHgDDVNCCAFSF--SLLATCSLDKTIRLY 37 5799*****888****6533..3589*********98 PP == domain 2 score: 27.8 bits; conditional E-value: 1.8e-07 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 l+ H+ v++++fsp+g+ las+s Dgt +W+ sp|Q8N9V3-2|WSDU1_HUMAN 50 LKFHTYaVHCCCFSPSGHILASCSTDGTTVLWN 82 6778335*************************8 PP == domain 3 score: 22.7 bits; conditional E-value: 7.8e-06 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v+ ++fspd++ lasG Dgtv +W+ sp|Q8N9V3-2|WSDU1_HUMAN 99 PVRVCQFSPDSTCLASGAADGTVVLWN 125 575555***********99*******8 PP == domain 4 score: 13.1 bits; conditional E-value: 0.0081 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++afsp+g+++++Gs g + +Wd sp|Q8N9V3-2|WSDU1_HUMAN 143 AACAFSPNGSFFVTGSSCGDLTVWD 167 4688***********8899999998 PP == domain 5 score: 16.5 bits; conditional E-value: 0.00071 EEEEEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 c ++ ++H ++t+++fs+ las++ D+ v+iW sp|Q8N9V3-2|WSDU1_HUMAN 172 CPHSEKAHdLGITCCDFSSQPVSdgeqglqffrLASCGQDCQVKIW 217 77777899555****86666666889999*9999************ PP >> tr|D6RBD0|D6RBD0_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 5.5e-05 0.0045 4 38 .] 8 44 .. 5 44 .. 0.87 2 ! 37.2 0.6 2e-10 1.7e-08 3 38 .] 55 91 .. 53 91 .. 0.93 3 ! 15.3 0.1 0.0017 0.14 16 38 .] 95 109 .. 92 109 .. 0.87 4 ! 25.8 1.0 7.9e-07 6.4e-05 9 38 .] 122 154 .. 112 154 .. 0.83 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 5.5e-05 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s+s+D+t+ +W+ tr|D6RBD0|D6RBD0_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRDKTIIMWK 44 5799***666****99888888899***********6 PP == domain 2 score: 37.2 bits; conditional E-value: 2e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6RBD0|D6RBD0_HUMAN 55 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 91 7899****667************99***********9 PP == domain 3 score: 15.3 bits; conditional E-value: 0.0017 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 + ++sGs+D+t+++W+ tr|D6RBD0|D6RBD0_HUMAN 95 Q--------IVSGSRDKTIKLWN 109 4........88***********8 PP == domain 4 score: 25.8 bits; conditional E-value: 7.9e-07 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|D6RBD0|D6RBD0_HUMAN 122 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 154 79666*************989***********8 PP >> sp|Q12834|CDC20_HUMAN Cell division cycle protein 20 homolog OS=Homo sapiens GN=CDC20 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 1 81 13 38 .] 229 254 .. 219 254 .. 0.88 2 ? 4.9 0.8 3.2 2.6e+02 3 35 .. 260 291 .. 258 294 .. 0.75 3 ! 28.0 0.4 1.6e-07 1.3e-05 3 37 .. 301 336 .. 299 336 .. 0.92 4 ! 23.2 0.6 5.2e-06 0.00043 2 38 .] 346 386 .. 345 386 .. 0.79 5 ! 13.6 0.3 0.0056 0.46 2 38 .] 391 429 .. 390 429 .. 0.88 6 ! 24.2 0.0 2.6e-06 0.00021 4 37 .. 436 470 .. 433 471 .. 0.91 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 1 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++s+a+ ++g++la G+ v +Wd sp|Q12834|CDC20_HUMAN 229 ISSVAWIKEGNYLAVGTSSAEVQLWD 254 99**************6699999998 PP == domain 2 score: 4.9 bits; conditional E-value: 3.2 EEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEE CS WD40 3 clrtltGH.ssvtslafspdgaw....lasGsdDgtvr 35 lr t H v sl +w l+sGs+ g+++ sp|Q12834|CDC20_HUMAN 260 RLRNMTSHsARVGSL------SWnsyiLSSGSRSGHIH 291 5788899*444****......5555558899*999996 PP == domain 3 score: 28.0 bits; conditional E-value: 1.6e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++ tl+GH + v++l++ pdg+ lasG+ D+ v +W sp|Q12834|CDC20_HUMAN 301 HVATLSGHsQEVCGLRWAPDGRHLASGGNDNLVNVW 336 5789****666************************* PP == domain 4 score: 23.2 bits; conditional E-value: 5.2e-06 EEEEEEESS.SSEEEEEEETTSSE.EEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasG..sdDgtvriWd 38 +l+t+t H + v ++a++p ++ la+G + D+++riW+ sp|Q12834|CDC20_HUMAN 346 VPLQTFTQHqGAVKAVAWCPWQSNvLATGggTSDRHIRIWN 386 689******777****88877777456874425*******8 PP == domain 5 score: 13.6 bits; conditional E-value: 0.0056 EEEEEEESSSSEEEEEEETTSSEEEEEE..TTSEEEEEE CS WD40 2 qclrtltGHssvtslafspdgawlasGs..dDgtvriWd 38 cl ++Hs v+s+ +sp+ + l+sG+ + + iW+ sp|Q12834|CDC20_HUMAN 391 ACLSAVDAHSQVCSILWSPHYKELISGHgfAQNQLVIWK 429 6899999**88****************645699999995 PP == domain 6 score: 24.2 bits; conditional E-value: 2.6e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+GH s v sl spdga +as+ D t+r+W sp|Q12834|CDC20_HUMAN 436 VAELKGHtSRVLSLTMSPDGATVASAAADETLRLW 470 6789***777**************9989******* PP >> sp|Q09028-4|RBBP4_HUMAN Isoform 4 of Histone-binding protein RBBP4 OS=Homo sapiens GN=RBBP4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.3 0.0024 0.2 7 38 .] 138 171 .. 132 171 .. 0.72 2 ! 13.4 0.3 0.0066 0.53 5 38 .] 186 221 .. 183 221 .. 0.74 3 ! 31.1 0.0 1.8e-08 1.4e-06 2 38 .] 229 267 .. 228 267 .. 0.90 4 ! 21.4 0.1 2e-05 0.0016 4 38 .] 275 311 .. 273 311 .. 0.85 5 ! 19.2 0.1 9.9e-05 0.0081 4 37 .. 332 367 .. 329 368 .. 0.85 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 0.0024 EESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 l+GH + ++l+++p+ + l+s+sdD+t+ +Wd sp|Q09028-4|RBBP4_HUMAN 138 LRGHqkEG-YGLSWNPNLSGhLLSASDDHTICLWD 171 56775333.577777766665569999*******9 PP == domain 2 score: 13.4 bits; conditional E-value: 0.0066 EEEESSSS.EEEEEEETTSSE......EEEEE..TTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgaw......lasGs..dDgtvriWd 38 +++tGH+ v ++ +w l+ Gs dD++++iWd sp|Q09028-4|RBBP4_HUMAN 186 TIFTGHTAvVEDV------SWhllhesLF-GSvaDDQKLMIWD 221 579***7757***......5544444488.76458*******9 PP == domain 3 score: 31.1 bits; conditional E-value: 1.8e-08 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++ ++H v++l+f+p++ ++ a+Gs D+tv +Wd sp|Q09028-4|RBBP4_HUMAN 229 KPSHSVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 267 68899****777************6379**********9 PP == domain 4 score: 21.4 bits; conditional E-value: 2e-05 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l++++ H++ + +++sp++ ++ s++ D+ + +Wd sp|Q09028-4|RBBP4_HUMAN 275 LHSFESHKDeIFQVQWSPHNETILaSSGTDRRLNVWD 311 89*****556************7525567*******9 PP == domain 5 score: 19.2 bits; conditional E-value: 9.9e-05 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ +W sp|Q09028-4|RBBP4_HUMAN 332 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQVW 367 56667**666************9977799****999 PP >> sp|O94967-2|WDR47_HUMAN Isoform 2 of WD repeat-containing protein 47 OS=Homo sapiens GN=WDR47 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.0 6.3 5.1e+02 3 36 .. 571 604 .. 569 604 .. 0.82 2 ! 24.9 0.0 1.6e-06 0.00013 9 36 .. 631 659 .. 621 659 .. 0.87 3 ! 21.7 1.2 1.6e-05 0.0013 1 38 [] 717 754 .. 717 754 .. 0.91 4 ! 16.4 0.0 0.00077 0.062 6 38 .] 767 800 .. 759 800 .. 0.81 5 ! 20.8 0.0 3.1e-05 0.0025 3 36 .. 806 840 .. 804 842 .. 0.90 6 ? 6.7 0.1 0.91 74 9 37 .. 858 887 .. 851 888 .. 0.61 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 6.3 EEEEEESSSSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtvri 36 c+ +l+ + v+++af+p g + a Gs +t+r+ sp|O94967-2|WDR47_HUMAN 571 CINILEDTQAVRAVAFHPAGGLYAVGSNSKTLRV 604 6666665556************999*99999997 PP == domain 2 score: 24.9 bits; conditional E-value: 1.6e-06 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 H +s++++a+sp g++la+Gs D+ v++ sp|O94967-2|WDR47_HUMAN 631 HHkGSIYCVAWSPCGQLLATGSNDKYVKV 659 57666**********************97 PP == domain 3 score: 21.7 bits; conditional E-value: 1.6e-05 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 gq l+ l+GH +++ +l +w +asGs D+tvr+Wd sp|O94967-2|WDR47_HUMAN 717 GQGLHALSGHtGHILAL-----YTWsgwmIASGSQDKTVRFWD 754 578999****888****.....888999999***********9 PP == domain 4 score: 16.4 bits; conditional E-value: 0.00077 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t+ G s v s+a++p+g++la+G +D +++++d sp|O94967-2|WDR47_HUMAN 767 TFHGTgSAVASVAVDPSGRLLATGQEDSSCMLYD 800 45555555****************89******98 PP == domain 5 score: 20.8 bits; conditional E-value: 3.1e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++++ H s+v+s++fsp ++l++Gs+D ++++ sp|O94967-2|WDR47_HUMAN 806 MVQSYHPHsSDVRSVRFSPGAHYLLTGSYDMKIKV 840 5789999*888**********************98 PP == domain 6 score: 6.7 bits; conditional E-value: 0.91 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 H++ v ++++ ++s+s D+tv +W sp|O94967-2|WDR47_HUMAN 858 EHKDkVIQCRWHTQDLSFLSSSADRTVTLW 887 56445445544444444456777******* PP >> sp|O00628|PEX7_HUMAN Peroxisomal targeting signal 2 receptor OS=Homo sapiens GN=PEX7 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.6 0.015 1.2 12 38 .] 69 96 .. 58 96 .. 0.75 2 ! 26.1 0.0 6.6e-07 5.3e-05 3 38 .] 103 141 .. 101 141 .. 0.87 3 ! 19.5 0.3 7.9e-05 0.0064 1 38 [] 145 184 .. 145 184 .. 0.74 4 ? 11.1 0.1 0.035 2.8 7 38 .] 194 227 .. 190 227 .. 0.80 5 ! 24.7 0.0 1.8e-06 0.00015 2 38 .] 233 271 .. 232 271 .. 0.87 6 ? 5.2 0.0 2.7 2.2e+02 14 38 .] 290 315 .. 277 315 .. 0.69 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.015 SEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 12 svtslafspdgawla.sGsdDgtvriWd 38 + ++ +s ++ ++ ++s Dg++ +Wd sp|O00628|PEX7_HUMAN 69 GLFDVTWSENNEHVLiTCSGDGSLQLWD 96 46789899999996448877*******9 PP == domain 2 score: 26.1 bits; conditional E-value: 6.6e-07 EEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 +l++++ H + v+s+ +w ++sGs+D+tv++Wd sp|O00628|PEX7_HUMAN 103 PLQVYKEHaQEVYSV------DWsqtrgeqlVVSGSWDQTVKLWD 141 7899****888****......777777779788***********9 PP == domain 3 score: 19.5 bits; conditional E-value: 7.9e-05 TEEEEEEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 g+ l t++GH s ++s w +as+s D+t+riWd sp|O00628|PEX7_HUMAN 145 GKSLCTFRGHeSIIYST------IWsphipgcFASASGDQTLRIWD 184 57789*****5558888......555555556677766*******9 PP == domain 4 score: 11.1 bits; conditional E-value: 0.035 EESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + +H + s+++++++ l++G D+++r Wd sp|O00628|PEX7_HUMAN 194 IPAHqAEILSCDWCKYNENlLVTGAVDCSLRGWD 227 4689666****888888884479*9********8 PP == domain 5 score: 24.7 bits; conditional E-value: 1.8e-06 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 q++ +l GH+ ++ ++fsp +a + as+s+D tvr+W+ sp|O00628|PEX7_HUMAN 233 QPVFELLGHTYaIRRVKFSPFHASVlASCSYDFTVRFWN 271 7899999**446************626899********8 PP == domain 6 score: 5.2 bits; conditional E-value: 2.7 EEEEEETTSSE.EEEEETTSEEEEEE CS WD40 14 tslafspdgaw.lasGsdDgtvriWd 38 ++l+fs ++ +a +s+D t++i+d sp|O00628|PEX7_HUMAN 290 CGLDFSLQSPTqVADCSWDETIKIYD 315 6776666666656669*********8 PP >> sp|Q9Y4P3|TBL2_HUMAN Transducin beta-like protein 2 OS=Homo sapiens GN=TBL2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.7 0.1 1.2e-09 1e-07 7 38 .] 86 118 .. 79 118 .. 0.90 2 ? 9.8 0.0 0.091 7.4 10 38 .] 187 216 .. 179 216 .. 0.79 3 ? 8.5 0.0 0.24 19 14 37 .. 233 256 .. 218 257 .. 0.87 4 ! 25.3 0.2 1.2e-06 9.4e-05 6 38 .] 274 307 .. 269 307 .. 0.91 5 ? 11.8 0.0 0.022 1.8 10 37 .. 372 399 .. 365 400 .. 0.85 Alignments for each domain: == domain 1 score: 34.7 bits; conditional E-value: 1.2e-09 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+ H +++++++fs++g++la++ dD+t+riW+ sp|Q9Y4P3|TBL2_HUMAN 86 LKSHsGNISCMDFSSNGKYLATCADDRTIRIWS 118 6789555*************************5 PP == domain 2 score: 9.8 bits; conditional E-value: 0.091 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +v ++ g++++++s D tv iW+ sp|Q9Y4P3|TBL2_HUMAN 187 HkAPVIDIGIANTGKFIMTASSDTTVLIWS 216 64445566678899***99877*******5 PP == domain 3 score: 8.5 bits; conditional E-value: 0.24 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 t+ a+sp g+++as++ + v++W sp|Q9Y4P3|TBL2_HUMAN 233 THAAVSPCGRFVASCGFTPDVKVW 256 56679*********999******* PP == domain 4 score: 25.3 bits; conditional E-value: 1.2e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH v+s+afs d++ +as s+Dgt ++Wd sp|Q9Y4P3|TBL2_HUMAN 274 ELKGHsAAVHSFAFSNDSRRMASVSKDGTWKLWD 307 589**555**************99*********9 PP == domain 5 score: 11.8 bits; conditional E-value: 0.022 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ++ l+f+ g++las++ D+ vr++ sp|Q9Y4P3|TBL2_HUMAN 372 HgECIANLSFDITGRFLASCG-DRAVRLF 399 644588899************.*****96 PP >> sp|Q09028-3|RBBP4_HUMAN Isoform 3 of Histone-binding protein RBBP4 OS=Homo sapiens GN=RBBP4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.3 0.0026 0.21 7 38 .] 173 206 .. 167 206 .. 0.72 2 ! 13.3 0.3 0.007 0.57 5 38 .] 221 256 .. 218 256 .. 0.74 3 ! 31.0 0.0 1.9e-08 1.5e-06 2 38 .] 264 302 .. 263 302 .. 0.90 4 ! 21.3 0.1 2.1e-05 0.0017 4 38 .] 310 346 .. 308 346 .. 0.85 5 ! 19.1 0.1 0.00011 0.0086 4 37 .. 367 402 .. 364 403 .. 0.85 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 0.0026 EESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 l+GH + ++l+++p+ + l+s+sdD+t+ +Wd sp|Q09028-3|RBBP4_HUMAN 173 LRGHqkEG-YGLSWNPNLSGhLLSASDDHTICLWD 206 56775333.577777766665569999*******9 PP == domain 2 score: 13.3 bits; conditional E-value: 0.007 EEEESSSS.EEEEEEETTSSE......EEEEE..TTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgaw......lasGs..dDgtvriWd 38 +++tGH+ v ++ +w l+ Gs dD++++iWd sp|Q09028-3|RBBP4_HUMAN 221 TIFTGHTAvVEDV------SWhllhesLF-GSvaDDQKLMIWD 256 579***7757***......5544444488.76458*******9 PP == domain 3 score: 31.0 bits; conditional E-value: 1.9e-08 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++ ++H v++l+f+p++ ++ a+Gs D+tv +Wd sp|Q09028-3|RBBP4_HUMAN 264 KPSHSVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 302 68899****777************6379**********9 PP == domain 4 score: 21.3 bits; conditional E-value: 2.1e-05 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l++++ H++ + +++sp++ ++ s++ D+ + +Wd sp|Q09028-3|RBBP4_HUMAN 310 LHSFESHKDeIFQVQWSPHNETILaSSGTDRRLNVWD 346 89*****556************7525567*******9 PP == domain 5 score: 19.1 bits; conditional E-value: 0.00011 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ +W sp|Q09028-3|RBBP4_HUMAN 367 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQVW 402 56667**666************9977799****999 PP >> sp|Q9Y2I8|WDR37_HUMAN WD repeat-containing protein 37 OS=Homo sapiens GN=WDR37 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.1 0.0014 0.11 2 38 .] 147 185 .. 146 185 .. 0.91 2 ! 26.6 0.1 4.6e-07 3.7e-05 1 37 [. 189 226 .. 189 227 .. 0.92 3 ? 6.1 0.1 1.4 1.1e+02 3 38 .] 273 309 .. 271 309 .. 0.76 4 ! 30.2 0.4 3.2e-08 2.6e-06 2 38 .] 314 351 .. 313 351 .. 0.94 5 ! 23.7 1.5 3.7e-06 0.0003 4 38 .] 360 394 .. 357 394 .. 0.78 6 ? 3.8 0.1 7.2 5.8e+02 8 34 .. 451 480 .. 445 484 .. 0.75 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 0.0014 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 q+++++ GH ++++++++ + ++ ++ ++s D+t +W+ sp|Q9Y2I8|WDR37_HUMAN 147 QLVKEYIGHrDGIWDVSVAKTQPVVLgTASADHTALLWS 185 78999****999*************976789*******5 PP == domain 2 score: 26.6 bits; conditional E-value: 4.6e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+cl ++ GH +sv+s++f+p+ ++ +++s D+t +iW sp|Q9Y2I8|WDR37_HUMAN 189 GKCLVKYAGHvGSVNSIKFHPSEQLALTASGDQTAHIW 226 69********999************887766******* PP == domain 3 score: 6.1 bits; conditional E-value: 1.4 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +l++l+ H++ v + ++ g+ +++s+D+t ++d sp|Q9Y2I8|WDR37_HUMAN 273 PLTSLKSHQGvVIASDWLVGGKQAVTASWDRTANLYD 309 7889999977445665777777778999****99998 PP == domain 4 score: 30.2 bits; conditional E-value: 3.2e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++ltGH + t+++++p +++++++s+D t r+Wd sp|Q9Y2I8|WDR37_HUMAN 314 ELVHSLTGHdQELTHCCTHPTQRLVVTSSRDTTFRLWD 351 679******777*************************9 PP == domain 5 score: 23.7 bits; conditional E-value: 3.7e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + ++ GH + vts f + +sGsdD+tv++Wd sp|Q9Y2I8|WDR37_HUMAN 360 VNVFQGHtDTVTSAVFTVGDNV-VSGSDDRTVKVWD 394 56899**666988856555555.69**********9 PP == domain 6 score: 3.8 bits; conditional E-value: 7.2 ESSSS..EEEEEEETTSSE..EEEEETTSEE CS WD40 8 tGHss..vtslafspdgaw..lasGsdDgtv 34 GH v++ a+s d++ l++++ D+ sp|Q9Y2I8|WDR37_HUMAN 451 QGH-RrmVCCSAWSEDHPVcnLFTCGFDRQA 480 589.347999999999999887777779875 PP >> sp|O94967|WDR47_HUMAN WD repeat-containing protein 47 OS=Homo sapiens GN=WDR47 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 6.5 5.3e+02 3 36 .. 599 632 .. 597 632 .. 0.82 2 ! 24.8 0.0 1.7e-06 0.00014 9 36 .. 659 687 .. 649 687 .. 0.87 3 ! 21.7 1.2 1.6e-05 0.0013 1 38 [] 745 782 .. 745 782 .. 0.91 4 ! 16.3 0.0 0.00079 0.064 6 38 .] 795 828 .. 787 828 .. 0.81 5 ! 20.7 0.0 3.2e-05 0.0026 3 36 .. 834 868 .. 832 870 .. 0.90 6 ? 6.6 0.1 0.94 76 9 37 .. 886 915 .. 879 916 .. 0.61 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.5 EEEEEESSSSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtvri 36 c+ +l+ + v+++af+p g + a Gs +t+r+ sp|O94967|WDR47_HUMAN 599 CINILEDTQAVRAVAFHPAGGLYAVGSNSKTLRV 632 6666665556************999*99999997 PP == domain 2 score: 24.8 bits; conditional E-value: 1.7e-06 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 H +s++++a+sp g++la+Gs D+ v++ sp|O94967|WDR47_HUMAN 659 HHkGSIYCVAWSPCGQLLATGSNDKYVKV 687 57666**********************97 PP == domain 3 score: 21.7 bits; conditional E-value: 1.6e-05 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 gq l+ l+GH +++ +l +w +asGs D+tvr+Wd sp|O94967|WDR47_HUMAN 745 GQGLHALSGHtGHILAL-----YTWsgwmIASGSQDKTVRFWD 782 578999****888****.....888999999***********9 PP == domain 4 score: 16.3 bits; conditional E-value: 0.00079 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t+ G s v s+a++p+g++la+G +D +++++d sp|O94967|WDR47_HUMAN 795 TFHGTgSAVASVAVDPSGRLLATGQEDSSCMLYD 828 45555555****************89******98 PP == domain 5 score: 20.7 bits; conditional E-value: 3.2e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++++ H s+v+s++fsp ++l++Gs+D ++++ sp|O94967|WDR47_HUMAN 834 MVQSYHPHsSDVRSVRFSPGAHYLLTGSYDMKIKV 868 5789999*888**********************98 PP == domain 6 score: 6.6 bits; conditional E-value: 0.94 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 H++ v ++++ ++s+s D+tv +W sp|O94967|WDR47_HUMAN 886 EHKDkVIQCRWHTQDLSFLSSSADRTVTLW 915 56445445544444444456777******* PP >> sp|O94967-3|WDR47_HUMAN Isoform 3 of WD repeat-containing protein 47 OS=Homo sapiens GN=WDR47 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 6.5 5.3e+02 3 36 .. 600 633 .. 598 633 .. 0.82 2 ! 24.8 0.0 1.7e-06 0.00014 9 36 .. 660 688 .. 650 688 .. 0.87 3 ! 21.7 1.2 1.6e-05 0.0013 1 38 [] 746 783 .. 746 783 .. 0.91 4 ! 16.3 0.0 0.0008 0.064 6 38 .] 796 829 .. 788 829 .. 0.81 5 ! 20.7 0.0 3.3e-05 0.0026 3 36 .. 835 869 .. 833 871 .. 0.90 6 ? 6.6 0.1 0.94 76 9 37 .. 887 916 .. 880 917 .. 0.61 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.5 EEEEEESSSSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtvri 36 c+ +l+ + v+++af+p g + a Gs +t+r+ sp|O94967-3|WDR47_HUMAN 600 CINILEDTQAVRAVAFHPAGGLYAVGSNSKTLRV 633 6666665556************999*99999997 PP == domain 2 score: 24.8 bits; conditional E-value: 1.7e-06 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 H +s++++a+sp g++la+Gs D+ v++ sp|O94967-3|WDR47_HUMAN 660 HHkGSIYCVAWSPCGQLLATGSNDKYVKV 688 57666**********************97 PP == domain 3 score: 21.7 bits; conditional E-value: 1.6e-05 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 gq l+ l+GH +++ +l +w +asGs D+tvr+Wd sp|O94967-3|WDR47_HUMAN 746 GQGLHALSGHtGHILAL-----YTWsgwmIASGSQDKTVRFWD 783 578999****888****.....888999999***********9 PP == domain 4 score: 16.3 bits; conditional E-value: 0.0008 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t+ G s v s+a++p+g++la+G +D +++++d sp|O94967-3|WDR47_HUMAN 796 TFHGTgSAVASVAVDPSGRLLATGQEDSSCMLYD 829 45555555****************89******98 PP == domain 5 score: 20.7 bits; conditional E-value: 3.3e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++++ H s+v+s++fsp ++l++Gs+D ++++ sp|O94967-3|WDR47_HUMAN 835 MVQSYHPHsSDVRSVRFSPGAHYLLTGSYDMKIKV 869 5789999*888**********************98 PP == domain 6 score: 6.6 bits; conditional E-value: 0.94 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 H++ v ++++ ++s+s D+tv +W sp|O94967-3|WDR47_HUMAN 887 EHKDkVIQCRWHTQDLSFLSSSADRTVTLW 916 56445445544444444456777******* PP >> sp|O94967-4|WDR47_HUMAN Isoform 4 of WD repeat-containing protein 47 OS=Homo sapiens GN=WDR47 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 6.6 5.4e+02 3 36 .. 607 640 .. 605 640 .. 0.82 2 ! 24.8 0.0 1.7e-06 0.00014 9 36 .. 667 695 .. 657 695 .. 0.87 3 ! 21.7 1.2 1.6e-05 0.0013 1 38 [] 753 790 .. 753 790 .. 0.91 4 ! 16.3 0.0 0.0008 0.065 6 38 .] 803 836 .. 795 836 .. 0.81 5 ! 20.7 0.0 3.3e-05 0.0027 3 36 .. 842 876 .. 840 878 .. 0.90 6 ? 6.6 0.1 0.95 77 9 37 .. 894 923 .. 887 924 .. 0.61 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.6 EEEEEESSSSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtvri 36 c+ +l+ + v+++af+p g + a Gs +t+r+ sp|O94967-4|WDR47_HUMAN 607 CINILEDTQAVRAVAFHPAGGLYAVGSNSKTLRV 640 6666665556************999*99999997 PP == domain 2 score: 24.8 bits; conditional E-value: 1.7e-06 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 H +s++++a+sp g++la+Gs D+ v++ sp|O94967-4|WDR47_HUMAN 667 HHkGSIYCVAWSPCGQLLATGSNDKYVKV 695 57666**********************97 PP == domain 3 score: 21.7 bits; conditional E-value: 1.6e-05 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 gq l+ l+GH +++ +l +w +asGs D+tvr+Wd sp|O94967-4|WDR47_HUMAN 753 GQGLHALSGHtGHILAL-----YTWsgwmIASGSQDKTVRFWD 790 578999****888****.....888999999***********9 PP == domain 4 score: 16.3 bits; conditional E-value: 0.0008 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t+ G s v s+a++p+g++la+G +D +++++d sp|O94967-4|WDR47_HUMAN 803 TFHGTgSAVASVAVDPSGRLLATGQEDSSCMLYD 836 45555555****************89******98 PP == domain 5 score: 20.7 bits; conditional E-value: 3.3e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++++ H s+v+s++fsp ++l++Gs+D ++++ sp|O94967-4|WDR47_HUMAN 842 MVQSYHPHsSDVRSVRFSPGAHYLLTGSYDMKIKV 876 5789999*888**********************98 PP == domain 6 score: 6.6 bits; conditional E-value: 0.95 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 H++ v ++++ ++s+s D+tv +W sp|O94967-4|WDR47_HUMAN 894 EHKDkVIQCRWHTQDLSFLSSSADRTVTLW 923 56445445544444444456777******* PP >> sp|O95834|EMAL2_HUMAN Echinoderm microtubule-associated protein-like 2 OS=Homo sapiens GN=EML2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.1 0.0011 0.091 2 38 .] 96 143 .. 95 143 .. 0.81 2 ? 3.4 0.2 9.9 8e+02 13 38 .] 162 191 .. 149 191 .. 0.69 3 ? 3.7 0.0 7.9 6.4e+02 18 37 .. 213 232 .. 196 233 .. 0.74 4 ? 5.7 0.0 1.8 1.5e+02 7 37 .. 246 278 .. 240 278 .. 0.82 5 ! 14.5 0.1 0.0031 0.25 4 37 .. 287 321 .. 284 321 .. 0.89 6 ! 14.4 0.2 0.0031 0.25 8 38 .] 374 405 .. 364 405 .. 0.89 7 ! 15.7 0.1 0.0012 0.099 9 37 .. 459 487 .. 449 488 .. 0.81 8 ! 14.1 1.5 0.0041 0.34 4 38 .] 499 534 .. 497 534 .. 0.86 9 ? 6.0 0.1 1.5 1.2e+02 11 31 .. 574 593 .. 563 596 .. 0.82 10 ! 18.3 0.5 0.00019 0.015 3 37 .. 610 646 .. 608 647 .. 0.86 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0011 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 q +r++ GH +++ +la +pd +a+G + ++vriWd sp|O95834|EMAL2_HUMAN 96 QRQRHYLGHnDDIKCLAIHPDMVTIATGqvaGTtkegkplPPHVRIWD 143 779******666*************99754422457778899999998 PP == domain 2 score: 3.4 bits; conditional E-value: 9.9 EEEEE..EETTSSEEEEE..ETTSEEEEEE CS WD40 13 vtsla..fspdgawlasG..sdDgtvriWd 38 v+++ s g++l++ s D+ + +Wd sp|O95834|EMAL2_HUMAN 162 VCCVGfsKSNGGNLLCAVdeSNDHMLSVWD 191 5555443566666775445556*******9 PP == domain 3 score: 3.7 bits; conditional E-value: 7.9 EETTSSE.EEEEETTSEEEEE CS WD40 18 fspdgaw.lasGsdDgtvriW 37 f+p + l++++ + ++++W sp|O95834|EMAL2_HUMAN 213 FHPTDPTvLITCG-KSHIYFW 232 77777783569**.******* PP == domain 4 score: 5.7 bits; conditional E-value: 1.8 EESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ss..vtslafspdgawlasGsdDgtvriW 37 ++ H ++ v ++ f g+ + +G+ g++++W sp|O95834|EMAL2_HUMAN 246 FEKHeKPkyVLCVTFLEGGDVV-TGDSGGNLYVW 278 677987788****999999996.7*66******9 PP == domain 5 score: 14.5 bits; conditional E-value: 0.0031 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l +H ++v +l+ +dg++++ G++D+ v +W sp|O95834|EMAL2_HUMAN 287 QAVLGAHdGGVFGLCALRDGTLVSGGGRDRRVVLW 321 67899**777************97668******** PP == domain 6 score: 14.4 bits; conditional E-value: 0.0031 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++la++p+ a +++++ D+ v++W+ sp|O95834|EMAL2_HUMAN 374 QGHvEELWGLATHPSRAQFVTCGQDKLVHLWS 405 5998889************************5 PP == domain 7 score: 15.7 bits; conditional E-value: 0.0012 SSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriW 37 G ++ ++fspdga+la Gs D+ v+++ sp|O95834|EMAL2_HUMAN 459 GNEQISVVSFSPDGAYLAVGSHDNLVYVY 487 333387889***********99**99987 PP == domain 8 score: 14.1 bits; conditional E-value: 0.0041 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++++GH s++t+l++ +d++ +++ s D + Wd sp|O95834|EMAL2_HUMAN 499 LGKCSGHsSFITHLDWAQDSSCFVTNSGDYEILYWD 534 67899**777************997555****9998 PP == domain 9 score: 6.0 bits; conditional E-value: 1.5 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 ++++++a s+dg++las++ D sp|O95834|EMAL2_HUMAN 574 TDINAVARSHDGKLLASAD-D 593 36*************9876.6 PP == domain 10 score: 18.3 bits; conditional E-value: 0.00019 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 + +++ GH s+vt +af d ++ l++G++D +v W sp|O95834|EMAL2_HUMAN 610 LSHKYGGHsSHVTNVAFLWDDSMaLTTGGKDTSVLQW 646 5799****888*****88888885579*********9 PP >> tr|J3KTB3|J3KTB3_HUMAN WD repeat and SOCS box-containing protein 1 (Fragment) OS=Homo sapiens GN=WSB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 0.0 1.3e-07 1.1e-05 2 38 .] 15 53 .. 14 53 .. 0.84 2 ! 27.5 0.1 2.3e-07 1.9e-05 2 38 .] 59 96 .. 58 96 .. 0.91 3 ! 35.3 0.1 8.1e-10 6.6e-08 4 38 .] 103 138 .. 100 138 .. 0.92 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 1.3e-07 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 ++l l H+ v++l f pdg+++ +s+s+D+t+r+Wd tr|J3KTB3|J3KTB3_HUMAN 15 KLLLNLVDHTEvVRDLTFAPDGSLIlVSASRDKTLRVWD 53 6677788896657***********62589*********9 PP == domain 2 score: 27.5 bits; conditional E-value: 2.3e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++l+GH ++v+s+afspd+++l+s + + v +W+ tr|J3KTB3|J3KTB3_HUMAN 59 NMMKVLRGHqNWVYSCAFSPDSSMLCSVGASKAVFLWN 96 66899****999*************98777*******8 PP == domain 3 score: 35.3 bits; conditional E-value: 8.1e-10 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r+l+GH +v +++fspdga+la++s+D v+iWd tr|J3KTB3|J3KTB3_HUMAN 103 IRKLEGHhHDVVACDFSPDGALLATASYDTRVYIWD 138 7899***77799***********************9 PP >> sp|Q09028-2|RBBP4_HUMAN Isoform 2 of Histone-binding protein RBBP4 OS=Homo sapiens GN=RBBP4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.3 0.0027 0.22 7 38 .] 172 205 .. 166 205 .. 0.72 2 ! 13.3 0.3 0.0073 0.59 5 38 .] 220 255 .. 217 255 .. 0.74 3 ! 30.9 0.0 2e-08 1.6e-06 2 38 .] 263 301 .. 262 301 .. 0.90 4 ! 21.2 0.1 2.2e-05 0.0018 4 38 .] 309 345 .. 307 345 .. 0.85 5 ! 19.0 0.1 0.00011 0.009 4 37 .. 366 401 .. 363 402 .. 0.85 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 0.0027 EESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 l+GH + ++l+++p+ + l+s+sdD+t+ +Wd sp|Q09028-2|RBBP4_HUMAN 172 LRGHqkEG-YGLSWNPNLSGhLLSASDDHTICLWD 205 56775333.577777766665569999*******9 PP == domain 2 score: 13.3 bits; conditional E-value: 0.0073 EEEESSSS.EEEEEEETTSSE......EEEEE..TTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgaw......lasGs..dDgtvriWd 38 +++tGH+ v ++ +w l+ Gs dD++++iWd sp|Q09028-2|RBBP4_HUMAN 220 TIFTGHTAvVEDV------SWhllhesLF-GSvaDDQKLMIWD 255 579***7757***......5544444488.76458*******9 PP == domain 3 score: 30.9 bits; conditional E-value: 2e-08 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++ ++H v++l+f+p++ ++ a+Gs D+tv +Wd sp|Q09028-2|RBBP4_HUMAN 263 KPSHSVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 301 68899****777************6379**********9 PP == domain 4 score: 21.2 bits; conditional E-value: 2.2e-05 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l++++ H++ + +++sp++ ++ s++ D+ + +Wd sp|Q09028-2|RBBP4_HUMAN 309 LHSFESHKDeIFQVQWSPHNETILaSSGTDRRLNVWD 345 89*****556************7525567*******9 PP == domain 5 score: 19.0 bits; conditional E-value: 0.00011 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ +W sp|Q09028-2|RBBP4_HUMAN 366 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQVW 401 56667**666************9977799****999 PP >> sp|Q09028|RBBP4_HUMAN Histone-binding protein RBBP4 OS=Homo sapiens GN=RBBP4 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.3 0.0027 0.22 7 38 .] 173 206 .. 167 206 .. 0.72 2 ! 13.3 0.3 0.0074 0.6 5 38 .] 221 256 .. 218 256 .. 0.74 3 ! 30.9 0.0 2e-08 1.6e-06 2 38 .] 264 302 .. 263 302 .. 0.90 4 ! 21.2 0.1 2.2e-05 0.0018 4 38 .] 310 346 .. 308 346 .. 0.85 5 ! 19.0 0.1 0.00011 0.009 4 37 .. 367 402 .. 364 403 .. 0.85 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.0027 EESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 l+GH + ++l+++p+ + l+s+sdD+t+ +Wd sp|Q09028|RBBP4_HUMAN 173 LRGHqkEG-YGLSWNPNLSGhLLSASDDHTICLWD 206 56775333.577777766665569999*******9 PP == domain 2 score: 13.3 bits; conditional E-value: 0.0074 EEEESSSS.EEEEEEETTSSE......EEEEE..TTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgaw......lasGs..dDgtvriWd 38 +++tGH+ v ++ +w l+ Gs dD++++iWd sp|Q09028|RBBP4_HUMAN 221 TIFTGHTAvVEDV------SWhllhesLF-GSvaDDQKLMIWD 256 579***7757***......5544444488.76458*******9 PP == domain 3 score: 30.9 bits; conditional E-value: 2e-08 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++ ++H v++l+f+p++ ++ a+Gs D+tv +Wd sp|Q09028|RBBP4_HUMAN 264 KPSHSVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 302 68899****777************6379**********9 PP == domain 4 score: 21.2 bits; conditional E-value: 2.2e-05 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l++++ H++ + +++sp++ ++ s++ D+ + +Wd sp|Q09028|RBBP4_HUMAN 310 LHSFESHKDeIFQVQWSPHNETILaSSGTDRRLNVWD 346 89*****556************7525567*******9 PP == domain 5 score: 19.0 bits; conditional E-value: 0.00011 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ +W sp|Q09028|RBBP4_HUMAN 367 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQVW 402 56667**666************9977799****999 PP >> sp|Q8NAA4|A16L2_HUMAN Autophagy-related protein 16-2 OS=Homo sapiens GN=ATG16L2 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.0 7e-07 5.7e-05 5 38 .] 330 364 .. 327 364 .. 0.94 2 ? 10.1 0.0 0.075 6.1 5 37 .. 374 407 .. 371 408 .. 0.86 3 ! 15.2 0.0 0.0019 0.15 5 38 .] 416 450 .. 412 450 .. 0.81 4 ? 9.3 0.2 0.14 11 24 38 .] 475 489 .. 459 489 .. 0.81 5 ! 14.2 0.1 0.0039 0.32 7 38 .] 499 530 .. 493 530 .. 0.81 6 ! 13.6 0.2 0.006 0.49 16 38 .] 554 576 .. 537 576 .. 0.86 7 ? 5.6 0.1 2 1.6e+02 10 37 .. 590 618 .. 581 619 .] 0.82 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 7e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++H s v++++f p++++la+G+ D+ +++W+ sp|Q8NAA4|A16L2_HUMAN 330 DVLDAHlSEVNAVRFGPNSSLLATGGADRLIHLWN 364 5799**999*************************8 PP == domain 2 score: 10.1 bits; conditional E-value: 0.075 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+G +s+ts++f+p+g ++++++++ +W sp|Q8NAA4|A16L2_HUMAN 374 QTLEGAgGSITSVDFDPSGYQVLAATYNQAAQLW 407 689999888************9999878888888 PP == domain 3 score: 15.2 bits; conditional E-value: 0.0019 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl+GH++ vt+ +f + ++Gs+D+tv+ Wd sp|Q8NAA4|A16L2_HUMAN 416 ETLSGHKDkVTAAKFKLTRHQAVTGSRDRTVKEWD 450 589***666****66555555889**********8 PP == domain 4 score: 9.3 bits; conditional E-value: 0.14 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 ++sG+ D+++r+Wd sp|Q8NAA4|A16L2_HUMAN 475 IIISGHNDQKIRFWD 489 2579**********9 PP == domain 5 score: 14.2 bits; conditional E-value: 0.0039 EESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtslafspdgawlasGsdDgtvriWd 38 + ++ vtsl+ s+d+ l+s+s+D+t+++ d sp|Q8NAA4|A16L2_HUMAN 499 IPVQGRVTSLSLSHDQLHLLSCSRDNTLKVID 530 444545***********************965 PP == domain 6 score: 13.6 bits; conditional E-value: 0.006 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 fspd ++ ++Gs Dg ++iWd sp|Q8NAA4|A16L2_HUMAN 554 AVFSPDRSYALAGSCDGALYIWD 576 44*******999*99*******9 PP == domain 7 score: 5.6 bits; conditional E-value: 2 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H v+++a++ +g+ ++s + ++v +W sp|Q8NAA4|A16L2_HUMAN 590 HcAAVNAVAWCYSGSHMVSVDQGRKVVLW 618 6555****999999999888889999999 PP >> sp|Q8TAF3-3|WDR48_HUMAN Isoform 3 of WD repeat-containing protein 48 OS=Homo sapiens GN=WDR48 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.066 5.3 11 38 .] 31 58 .. 25 58 .. 0.89 2 ? 8.1 0.2 0.33 27 7 38 .] 71 94 .. 66 94 .. 0.83 3 ! 21.0 0.0 2.7e-05 0.0022 3 38 .] 100 136 .. 98 136 .. 0.93 4 ! 15.1 0.0 0.002 0.16 4 38 .] 152 187 .. 149 187 .. 0.92 5 ! 24.0 0.1 2.9e-06 0.00024 4 38 .] 194 229 .. 191 229 .. 0.90 6 ? 10.6 0.1 0.052 4.2 2 35 .. 234 268 .. 233 271 .. 0.88 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.066 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v++l+ +p + l+++++D +riW+ sp|Q8TAF3-3|WDR48_HUMAN 31 NGVNALQLDPALNRLFTAGRDSIIRIWS 58 56999999999999*99999*******5 PP == domain 2 score: 8.1 bits; conditional E-value: 0.33 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H ++v+++ ++++ +t+++W+ sp|Q8TAF3-3|WDR48_HUMAN 71 MEHHtDWVNDI--------VLCCN-GKTLKVWN 94 5668667****........**888.*******8 PP == domain 3 score: 21.0 bits; conditional E-value: 2.7e-05 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 c+ tl++H++ v +la+ +d+ ++as++ D+ + +Wd sp|Q8TAF3-3|WDR48_HUMAN 100 CMSTLRTHKDyVKALAYAKDKELVASAGLDRQIFLWD 136 999*****666**************9999*******9 PP == domain 4 score: 15.1 bits; conditional E-value: 0.002 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +l+G +s++sla ++ g+ ++sGs + +r+Wd sp|Q8TAF3-3|WDR48_HUMAN 152 TSSLSGNkDSIYSLAMNQLGTIIVSGSTEKVLRVWD 187 56899**777*************************9 PP == domain 5 score: 24.0 bits; conditional E-value: 2.9e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l+GH ++v +l ++dg+ +sGs Dgt+r+W+ sp|Q8TAF3-3|WDR48_HUMAN 194 LMKLKGHtDNVKALLLNRDGTQCLSGSSDGTIRLWS 229 7789***766****************99*******5 PP == domain 6 score: 10.6 bits; conditional E-value: 0.052 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvr 35 +c+ t++ H +v++l++++ + + sG++D++++ sp|Q8TAF3-3|WDR48_HUMAN 234 RCIATYRVHdEGVWALQVNDAFTHVYSGGRDRKIY 268 79*******777****888888889*******996 PP >> tr|E9PC52|E9PC52_HUMAN Histone-binding protein RBBP7 OS=Homo sapiens GN=RBBP7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.4 0.0053 0.43 15 38 .] 172 196 .. 157 196 .. 0.60 2 ! 14.5 0.2 0.003 0.24 6 38 .] 212 246 .. 208 246 .. 0.75 3 ! 28.6 0.0 1e-07 8.4e-06 3 38 .] 255 292 .. 253 292 .. 0.86 4 ! 21.4 0.2 2e-05 0.0016 4 38 .] 300 336 .. 298 336 .. 0.85 5 ! 19.9 0.1 6e-05 0.0048 4 37 .. 357 392 .. 354 393 .. 0.85 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.0053 EEEEETTSSE...EEEEETTSEEEEEE CS WD40 15 slafspdgaw...lasGsdDgtvriWd 38 +l+++++ + l+s+sdD+tv +Wd tr|E9PC52|E9PC52_HUMAN 172 GLSWNSN--LsghLLSASDDHTVCLWD 196 4432222..1334568999*******9 PP == domain 2 score: 14.5 bits; conditional E-value: 0.003 EEESSSS.EEEEEEETTSSEEEEEE..TTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGs..dDgtvriWd 38 ++tGHs v ++a++ + l+ Gs dD++++iWd tr|E9PC52|E9PC52_HUMAN 212 IFTGHSAvVEDVAWHLLHESLF-GSvaDDQKLMIWD 246 79***7767***5544444488.76458*******9 PP == domain 3 score: 28.6 bits; conditional E-value: 1e-07 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + + ++H v++l+f+p++ ++ a+Gs D+tv +Wd tr|E9PC52|E9PC52_HUMAN 255 PSHLVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 292 5677789*666************6379**********9 PP == domain 4 score: 21.4 bits; conditional E-value: 2e-05 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l+t++ H++ + + +sp++ ++ s++ D+ + +Wd tr|E9PC52|E9PC52_HUMAN 300 LHTFESHKDeIFQVHWSPHNETILaSSGTDRRLNVWD 336 8******556************7525567*******9 PP == domain 5 score: 19.9 bits; conditional E-value: 6e-05 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ iW tr|E9PC52|E9PC52_HUMAN 357 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQIW 392 56667**666************9977799******* PP >> sp|Q16576|RBBP7_HUMAN Histone-binding protein RBBP7 OS=Homo sapiens GN=RBBP7 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.4 0.0054 0.44 15 38 .] 181 205 .. 166 205 .. 0.60 2 ! 14.5 0.2 0.0031 0.25 6 38 .] 221 255 .. 217 255 .. 0.75 3 ! 28.6 0.0 1.1e-07 8.7e-06 3 38 .] 264 301 .. 262 301 .. 0.86 4 ! 21.4 0.2 2e-05 0.0016 4 38 .] 309 345 .. 307 345 .. 0.85 5 ! 19.9 0.1 6.2e-05 0.005 4 37 .. 366 401 .. 363 402 .. 0.85 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.0054 EEEEETTSSE...EEEEETTSEEEEEE CS WD40 15 slafspdgaw...lasGsdDgtvriWd 38 +l+++++ + l+s+sdD+tv +Wd sp|Q16576|RBBP7_HUMAN 181 GLSWNSN--LsghLLSASDDHTVCLWD 205 4432222..1334568999*******9 PP == domain 2 score: 14.5 bits; conditional E-value: 0.0031 EEESSSS.EEEEEEETTSSEEEEEE..TTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGs..dDgtvriWd 38 ++tGHs v ++a++ + l+ Gs dD++++iWd sp|Q16576|RBBP7_HUMAN 221 IFTGHSAvVEDVAWHLLHESLF-GSvaDDQKLMIWD 255 79***7767***5544444488.76458*******9 PP == domain 3 score: 28.6 bits; conditional E-value: 1.1e-07 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + + ++H v++l+f+p++ ++ a+Gs D+tv +Wd sp|Q16576|RBBP7_HUMAN 264 PSHLVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 301 5677789*666************6379**********9 PP == domain 4 score: 21.4 bits; conditional E-value: 2e-05 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l+t++ H++ + + +sp++ ++ s++ D+ + +Wd sp|Q16576|RBBP7_HUMAN 309 LHTFESHKDeIFQVHWSPHNETILaSSGTDRRLNVWD 345 8******556************7525567*******9 PP == domain 5 score: 19.9 bits; conditional E-value: 6.2e-05 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ iW sp|Q16576|RBBP7_HUMAN 366 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQIW 401 56667**666************9977799******* PP >> sp|Q13347|EIF3I_HUMAN Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens GN=EIF3I PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0046 0.38 7 37 .. 6 37 .. 3 37 .. 0.94 2 ! 27.3 1.6 2.8e-07 2.3e-05 2 38 .] 43 80 .. 42 80 .. 0.86 3 ? 11.6 0.0 0.025 2 7 38 .] 184 216 .. 178 216 .. 0.86 4 ! 25.2 0.0 1.2e-06 0.0001 6 36 .. 280 311 .. 275 312 .. 0.90 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0046 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH s+t ++++++g++l++ +D+ v +W sp|Q13347|EIF3I_HUMAN 6 LQGHeRSITQIKYNREGDLLFTVAKDPIVNVW 37 67**888************************* PP == domain 2 score: 27.3 bits; conditional E-value: 2.8e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + l+t+ GH + v++++ + d + +++Gs D+++r+Wd sp|Q13347|EIF3I_HUMAN 43 ERLGTYMGHtGAVWCVDADWDTKHVLTGSADNSCRLWD 80 5689999**777****7777777799***********9 PP == domain 3 score: 11.6 bits; conditional E-value: 0.025 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 + Hs +++++ s+d ++++++s+D+t +++d sp|Q13347|EIF3I_HUMAN 184 VKEHSRqINDIQLSRDMTMFVTASKDNTAKLFD 216 5789446************************98 PP == domain 4 score: 25.2 bits; conditional E-value: 1.2e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvri 36 +GH ++++s+af+pdg+ +sG++Dg vri sp|Q13347|EIF3I_HUMAN 280 RVKGHfGPINSVAFHPDGKSYSSGGEDGYVRI 311 568**888************999********9 PP >> sp|Q5JSH3-3|WDR44_HUMAN Isoform 3 of WD repeat-containing protein 44 OS=Homo sapiens GN=WDR44 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.1 4.4e-05 0.0036 9 37 .. 36 65 .. 27 65 .. 0.87 2 ! 23.2 0.1 5.5e-06 0.00045 3 37 .. 126 160 .. 124 161 .. 0.85 3 ! 21.2 0.1 2.2e-05 0.0018 2 38 .] 166 203 .. 165 203 .. 0.83 4 ? 7.4 0.0 0.52 42 9 38 .] 217 247 .. 206 247 .. 0.85 5 ? 3.7 0.0 7.9 6.4e+02 13 38 .] 272 297 .. 255 297 .. 0.67 6 ! 16.3 0.1 0.0008 0.065 13 38 .] 317 341 .. 302 341 .. 0.74 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 4.4e-05 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 H + v+ ++fs+ g++las++ D+ vriW sp|Q5JSH3-3|WDR44_HUMAN 36 EHmGAVWTMKFSHCGRLLASAGQDNVVRIW 65 47888************************* PP == domain 2 score: 23.2 bits; conditional E-value: 5.5e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +++GH + +l++s++ +l+ +s+D+tvr+W sp|Q5JSH3-3|WDR44_HUMAN 126 PFCKYKGHtADLLDLSWSKNYFLLS-SSMDKTVRLW 160 56689***88899*******99985.666******* PP == domain 3 score: 21.2 bits; conditional E-value: 2.2e-05 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +cl + H ++vt++af+p + ++sGs Dg++r+W+ sp|Q5JSH3-3|WDR44_HUMAN 166 ECLCCF-QHiDFVTAIAFHPRDDRyFLSGSLDGKLRLWN 203 677778.59999*****7666666688***********8 PP == domain 4 score: 7.4 bits; conditional E-value: 0.52 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 G+ + +t+ f+++g++ + G++Dg + ++d sp|Q5JSH3-3|WDR44_HUMAN 217 GQtKLITAANFCQNGKYAVIGTYDGRCIFYD 247 6634499999*******999*99***99987 PP == domain 5 score: 3.7 bits; conditional E-value: 7.9 EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw.lasGsdDgtvriWd 38 +t++ p + l+++ D +r++d sp|Q5JSH3-3|WDR44_HUMAN 272 ITGIEPLPGENKiLVTSN-DSRIRLYD 297 777775555555156655.******98 PP == domain 6 score: 16.3 bits; conditional E-value: 0.0008 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +fs+d ++l+sGs+D+ v+iW+ sp|Q5JSH3-3|WDR44_HUMAN 317 I-KASFSHDFTYLVSGSEDKYVYIWS 341 3.3459*******************5 PP >> sp|O95834-2|EMAL2_HUMAN Isoform 2 of Echinoderm microtubule-associated protein-like 2 OS=Homo sapiens GN=EML2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.1 0.0014 0.12 2 38 .] 243 290 .. 242 290 .. 0.80 2 ? 3.4 0.0 10 8.1e+02 18 37 .. 360 379 .. 343 380 .. 0.74 3 ? 5.4 0.0 2.4 1.9e+02 7 37 .. 393 425 .. 387 425 .. 0.82 4 ! 14.1 0.1 0.004 0.32 4 37 .. 434 468 .. 431 468 .. 0.89 5 ! 14.1 0.1 0.0041 0.33 8 38 .] 521 552 .. 512 552 .. 0.89 6 ! 15.4 0.1 0.0016 0.13 9 37 .. 606 634 .. 596 635 .. 0.81 7 ! 13.7 1.5 0.0053 0.43 4 38 .] 646 681 .. 644 681 .. 0.86 8 ? 5.6 0.1 1.9 1.6e+02 11 31 .. 721 740 .. 710 743 .. 0.82 9 ! 18.0 0.5 0.00024 0.019 3 37 .. 757 793 .. 755 794 .. 0.86 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 0.0014 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 q +r++ GH +++ +la +pd +a+G + ++vriWd sp|O95834-2|EMAL2_HUMAN 243 QRQRHYLGHnDDIKCLAIHPDMVTIATGqvaGTtkegkplPPHVRIWD 290 779******666*************99754422457778899999998 PP == domain 2 score: 3.4 bits; conditional E-value: 10 EETTSSE.EEEEETTSEEEEE CS WD40 18 fspdgaw.lasGsdDgtvriW 37 f+p + l++++ + ++++W sp|O95834-2|EMAL2_HUMAN 360 FHPTDPTvLITCG-KSHIYFW 379 77777773569**.******* PP == domain 3 score: 5.4 bits; conditional E-value: 2.4 EESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ss..vtslafspdgawlasGsdDgtvriW 37 ++ H ++ v ++ f g+ + +G+ g++++W sp|O95834-2|EMAL2_HUMAN 393 FEKHeKPkyVLCVTFLEGGDVV-TGDSGGNLYVW 425 677987788****999999996.7*66******9 PP == domain 4 score: 14.1 bits; conditional E-value: 0.004 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l +H ++v +l+ +dg++++ G++D+ v +W sp|O95834-2|EMAL2_HUMAN 434 QAVLGAHdGGVFGLCALRDGTLVSGGGRDRRVVLW 468 67899**777************97668******** PP == domain 5 score: 14.1 bits; conditional E-value: 0.0041 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++la++p+ a +++++ D+ v++W+ sp|O95834-2|EMAL2_HUMAN 521 QGHvEELWGLATHPSRAQFVTCGQDKLVHLWS 552 5998889************************5 PP == domain 6 score: 15.4 bits; conditional E-value: 0.0016 SSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriW 37 G ++ ++fspdga+la Gs D+ v+++ sp|O95834-2|EMAL2_HUMAN 606 GNEQISVVSFSPDGAYLAVGSHDNLVYVY 634 333387889***********99**99987 PP == domain 7 score: 13.7 bits; conditional E-value: 0.0053 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++++GH s++t+l++ +d++ +++ s D + Wd sp|O95834-2|EMAL2_HUMAN 646 LGKCSGHsSFITHLDWAQDSSCFVTNSGDYEILYWD 681 67899**777************997555****9998 PP == domain 8 score: 5.6 bits; conditional E-value: 1.9 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 ++++++a s+dg++las++ D sp|O95834-2|EMAL2_HUMAN 721 TDINAVARSHDGKLLASAD-D 740 36*************9876.6 PP == domain 9 score: 18.0 bits; conditional E-value: 0.00024 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 + +++ GH s+vt +af d ++ l++G++D +v W sp|O95834-2|EMAL2_HUMAN 757 LSHKYGGHsSHVTNVAFLWDDSMaLTTGGKDTSVLQW 793 5799****888*****88888885579*********9 PP >> sp|Q96J01|THOC3_HUMAN THO complex subunit 3 OS=Homo sapiens GN=THOC3 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.1 6.4e-05 0.0052 4 36 .. 48 81 .. 40 82 .. 0.83 2 ! 25.6 0.3 9.1e-07 7.4e-05 6 38 .] 94 128 .. 89 128 .. 0.84 3 ? 9.0 0.0 0.16 13 13 34 .. 145 165 .. 132 169 .. 0.75 4 ! 23.5 0.0 4.4e-06 0.00036 2 38 .] 215 252 .. 214 252 .. 0.91 5 ? 12.0 0.1 0.019 1.5 12 33 .. 268 289 .. 257 291 .. 0.81 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 6.4e-05 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvri 36 +r++ +Hs v+s+a+s dg+ lasGs D+t + sp|Q96J01|THOC3_HUMAN 48 TREFLAHSAkVHSVAWSCDGRRLASGSFDKTASV 81 5677788336*****************9**9765 PP == domain 2 score: 25.6 bits; conditional E-value: 9.1e-07 EEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++GH +sv l+++p+++ l +++s D+t+riWd sp|Q96J01|THOC3_HUMAN 94 NYRGHgDSVDQLCWHPSNPDLfVTASGDKTIRIWD 128 599**888*****99999997346666*******9 PP == domain 3 score: 9.0 bits; conditional E-value: 0.16 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 + +++spdg+ +a G +D v sp|Q96J01|THOC3_HUMAN 145 I-NICWSPDGQTIAVGNKDDVV 165 6.789***********988766 PP == domain 4 score: 23.5 bits; conditional E-value: 4.4e-06 EEEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 ++++++ +H +++ +++f+p g+++a+Gs D v +Wd sp|Q96J01|THOC3_HUMAN 215 KPVQSINAHpsNCI-CIKFDPMGKYFATGSADALVSLWD 252 6899999**95558.***********************9 PP == domain 5 score: 12.0 bits; conditional E-value: 0.019 SEEEEEEETTSSEEEEEETTSE CS WD40 12 svtslafspdgawlasGsdDgt 33 +v+ l+fs+dg++las+s+D+ sp|Q96J01|THOC3_HUMAN 268 PVRTLSFSHDGKMLASASEDHF 289 389999*************996 PP >> tr|L7N2F8|L7N2F8_HUMAN Protein HIRA OS=Homo sapiens GN=HIRA PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.1 7.8e-07 6.3e-05 9 38 .] 24 54 .. 17 54 .. 0.90 2 ! 34.4 3.6 1.6e-09 1.3e-07 1 38 [] 77 115 .. 77 115 .. 0.95 3 ! 22.6 0.0 8.6e-06 0.0007 3 37 .. 122 157 .. 120 158 .. 0.89 4 ? 10.7 0.1 0.048 3.9 9 29 .. 177 197 .. 169 202 .. 0.79 5 ? 5.4 0.5 2.2 1.8e+02 7 37 .. 220 268 .. 214 268 .. 0.58 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 7.8e-07 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +v+++++s +g +lasG+dD+ +++W+ tr|L7N2F8|L7N2F8_HUMAN 24 NHlACVNCVRWSNSGMYLASGGDDKLIMVWK 54 68888*************************6 PP == domain 2 score: 34.4 bits; conditional E-value: 1.6e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++c+ +l+ H ++v ++a+sp+ awlas+s D+tv iW+ tr|L7N2F8|L7N2F8_HUMAN 77 WRCVSILRNHsGDVMDVAWSPHDAWLASCSVDNTVVIWN 115 68********777*************************8 PP == domain 3 score: 22.6 bits; conditional E-value: 8.6e-06 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriW 37 l tl+GHs+ v +l ++p g+++as dD+++++W tr|L7N2F8|L7N2F8_HUMAN 122 ILATLRGHSGlVKGLTWDPVGKYIASQADDRSLKVW 157 5789****7789***********986588******* PP == domain 4 score: 10.7 bits; conditional E-value: 0.048 SSSSEEEEEEETTSSEEEEEE CS WD40 9 GHssvtslafspdgawlasGs 29 G ++v l++spdg++l+s++ tr|L7N2F8|L7N2F8_HUMAN 177 GTTHVLRLSWSPDGHYLVSAH 197 3344**************986 PP == domain 5 score: 5.4 bits; conditional E-value: 2.2 EESS.SSEEEEE...............EETTSSE..EEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla...............fspdgaw..lasGsdDgtvriW 37 + GH + vt ++ p+ ++ a Gs+D+++ +W tr|L7N2F8|L7N2F8_HUMAN 220 FVGHrKAVTVVKfnpkifkkkqkngssAKPSCPYccCAVGSKDRSLSVW 268 5677666766655555555554444442222223324569********9 PP >> sp|Q16576-2|RBBP7_HUMAN Isoform 2 of Histone-binding protein RBBP7 OS=Homo sapiens GN=RBBP7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.4 0.0061 0.5 15 38 .] 225 249 .. 210 249 .. 0.60 2 ! 14.3 0.2 0.0035 0.28 6 38 .] 265 299 .. 261 299 .. 0.75 3 ! 28.4 0.0 1.2e-07 9.9e-06 3 38 .] 308 345 .. 306 345 .. 0.86 4 ! 21.2 0.2 2.3e-05 0.0019 4 38 .] 353 389 .. 351 389 .. 0.85 5 ! 19.7 0.1 7e-05 0.0057 4 37 .. 410 445 .. 407 446 .. 0.85 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.0061 EEEEETTSSE...EEEEETTSEEEEEE CS WD40 15 slafspdgaw...lasGsdDgtvriWd 38 +l+++++ + l+s+sdD+tv +Wd sp|Q16576-2|RBBP7_HUMAN 225 GLSWNSN--LsghLLSASDDHTVCLWD 249 4432222..1334568999*******9 PP == domain 2 score: 14.3 bits; conditional E-value: 0.0035 EEESSSS.EEEEEEETTSSEEEEEE..TTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGs..dDgtvriWd 38 ++tGHs v ++a++ + l+ Gs dD++++iWd sp|Q16576-2|RBBP7_HUMAN 265 IFTGHSAvVEDVAWHLLHESLF-GSvaDDQKLMIWD 299 79***7767***5544444488.76458*******9 PP == domain 3 score: 28.4 bits; conditional E-value: 1.2e-07 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + + ++H v++l+f+p++ ++ a+Gs D+tv +Wd sp|Q16576-2|RBBP7_HUMAN 308 PSHLVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 345 5677789*666************6379**********9 PP == domain 4 score: 21.2 bits; conditional E-value: 2.3e-05 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l+t++ H++ + + +sp++ ++ s++ D+ + +Wd sp|Q16576-2|RBBP7_HUMAN 353 LHTFESHKDeIFQVHWSPHNETILaSSGTDRRLNVWD 389 8******556************7525567*******9 PP == domain 5 score: 19.7 bits; conditional E-value: 7e-05 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ iW sp|Q16576-2|RBBP7_HUMAN 410 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQIW 445 55667**666************9977799******* PP >> sp|O95834-3|EMAL2_HUMAN Isoform 3 of Echinoderm microtubule-associated protein-like 2 OS=Homo sapiens GN=EML2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.1 0.0015 0.12 2 38 .] 297 344 .. 296 344 .. 0.80 2 ? 5.2 0.0 2.5 2.1e+02 7 37 .. 447 479 .. 441 479 .. 0.82 3 ! 14.0 0.1 0.0043 0.35 4 37 .. 488 522 .. 485 522 .. 0.89 4 ! 14.0 0.1 0.0044 0.36 8 38 .] 575 606 .. 566 606 .. 0.89 5 ! 15.3 0.1 0.0017 0.14 9 37 .. 660 688 .. 650 689 .. 0.81 6 ! 13.6 1.5 0.0057 0.46 4 38 .] 700 735 .. 698 735 .. 0.86 7 ? 5.5 0.1 2.1 1.7e+02 11 31 .. 775 794 .. 764 797 .. 0.82 8 ! 17.9 0.5 0.00026 0.021 3 37 .. 811 847 .. 809 848 .. 0.86 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0015 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 q +r++ GH +++ +la +pd +a+G + ++vriWd sp|O95834-3|EMAL2_HUMAN 297 QRQRHYLGHnDDIKCLAIHPDMVTIATGqvaGTtkegkplPPHVRIWD 344 779******666*************99754422457778899999998 PP == domain 2 score: 5.2 bits; conditional E-value: 2.5 EESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ss..vtslafspdgawlasGsdDgtvriW 37 ++ H ++ v ++ f g+ + +G+ g++++W sp|O95834-3|EMAL2_HUMAN 447 FEKHeKPkyVLCVTFLEGGDVV-TGDSGGNLYVW 479 677987788****999999996.7*66******9 PP == domain 3 score: 14.0 bits; conditional E-value: 0.0043 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l +H ++v +l+ +dg++++ G++D+ v +W sp|O95834-3|EMAL2_HUMAN 488 QAVLGAHdGGVFGLCALRDGTLVSGGGRDRRVVLW 522 67899**777************97668******** PP == domain 4 score: 14.0 bits; conditional E-value: 0.0044 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++la++p+ a +++++ D+ v++W+ sp|O95834-3|EMAL2_HUMAN 575 QGHvEELWGLATHPSRAQFVTCGQDKLVHLWS 606 5998889************************5 PP == domain 5 score: 15.3 bits; conditional E-value: 0.0017 SSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriW 37 G ++ ++fspdga+la Gs D+ v+++ sp|O95834-3|EMAL2_HUMAN 660 GNEQISVVSFSPDGAYLAVGSHDNLVYVY 688 333387889***********99**99987 PP == domain 6 score: 13.6 bits; conditional E-value: 0.0057 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++++GH s++t+l++ +d++ +++ s D + Wd sp|O95834-3|EMAL2_HUMAN 700 LGKCSGHsSFITHLDWAQDSSCFVTNSGDYEILYWD 735 67899**777************997555****9998 PP == domain 7 score: 5.5 bits; conditional E-value: 2.1 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 ++++++a s+dg++las++ D sp|O95834-3|EMAL2_HUMAN 775 TDINAVARSHDGKLLASAD-D 794 36*************9876.6 PP == domain 8 score: 17.9 bits; conditional E-value: 0.00026 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 + +++ GH s+vt +af d ++ l++G++D +v W sp|O95834-3|EMAL2_HUMAN 811 LSHKYGGHsSHVTNVAFLWDDSMaLTTGGKDTSVLQW 847 5799****888*****88888885579*********9 PP >> sp|Q8NA23-2|WDR31_HUMAN Isoform 2 of WD repeat-containing protein 31 OS=Homo sapiens GN=WDR31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 1.3 1.1e+02 9 35 .. 59 85 .. 51 88 .. 0.74 2 ! 19.9 0.0 6e-05 0.0049 2 38 .] 93 130 .. 92 130 .. 0.77 3 ! 28.0 0.0 1.7e-07 1.4e-05 3 38 .] 137 173 .. 135 173 .. 0.89 4 ! 14.4 0.0 0.0033 0.27 13 38 .] 190 215 .. 175 215 .. 0.84 5 ! 16.9 0.0 0.00053 0.043 4 38 .] 270 309 .. 267 309 .. 0.74 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 1.3 SS.SS...EEEEEEETTSSEEEEEETTSEEE CS WD40 9 GH.ss...vtslafspdgawlasGsdDgtvr 35 +H + v +l ++++ +sG++D+tv sp|Q8NA23-2|WDR31_HUMAN 59 AHmDTvsvVAAL----NSDLCVSGGKDKTVV 85 676554444677....999999*******96 PP == domain 2 score: 19.9 bits; conditional E-value: 6e-05 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + ++ ++GH + +t +a p ++ ++s+s+D+ v++Wd sp|Q8NA23-2|WDR31_HUMAN 93 NVVKRFKGHEHeITKVACIPKSSQFFSASRDRMVMMWD 130 67889****555999995555555568999*******9 PP == domain 3 score: 28.0 bits; conditional E-value: 1.7e-07 EEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 + + l GH vt+la+spd++ l++Gs+D+t+ +Wd sp|Q8NA23-2|WDR31_HUMAN 137 PRQQLCGH-AmvVTGLAVSPDSSQLCTGSRDNTLLLWD 173 667788**.6668************************9 PP == domain 4 score: 14.4 bits; conditional E-value: 0.0033 EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 13 vtslafspdgawla.sGsdDgtvriWd 38 vt+l++ p ++++ + s+D+t+r+Wd sp|Q8NA23-2|WDR31_HUMAN 190 VTHLCWVPREPYILqT-SEDKTLRLWD 215 8*************77.66*******9 PP == domain 5 score: 16.9 bits; conditional E-value: 0.00053 EEEEESS.SSE.EEEEEETTSSE..........EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssv.tslafspdgaw..........lasGsdDgtvriWd 38 + +++GH + v +++ + +a++s D++v+iW+ sp|Q8NA23-2|WDR31_HUMAN 270 ICEYKGHfQTVaSCV-------FlpralalmplIATSSHDCKVKIWN 309 56799**77796666.......44555556887788888*******8 PP >> sp|Q8NA23|WDR31_HUMAN WD repeat-containing protein 31 OS=Homo sapiens GN=WDR31 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 1.3 1.1e+02 9 35 .. 60 86 .. 52 89 .. 0.74 2 ! 19.9 0.0 6e-05 0.0049 2 38 .] 94 131 .. 93 131 .. 0.77 3 ! 28.0 0.0 1.7e-07 1.4e-05 3 38 .] 138 174 .. 136 174 .. 0.89 4 ! 14.4 0.0 0.0033 0.27 13 38 .] 191 216 .. 176 216 .. 0.84 5 ! 16.9 0.0 0.00054 0.044 4 38 .] 271 310 .. 268 310 .. 0.74 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 1.3 SS.SS...EEEEEEETTSSEEEEEETTSEEE CS WD40 9 GH.ss...vtslafspdgawlasGsdDgtvr 35 +H + v +l ++++ +sG++D+tv sp|Q8NA23|WDR31_HUMAN 60 AHmDTvsvVAAL----NSDLCVSGGKDKTVV 86 676554444677....999999*******96 PP == domain 2 score: 19.9 bits; conditional E-value: 6e-05 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + ++ ++GH + +t +a p ++ ++s+s+D+ v++Wd sp|Q8NA23|WDR31_HUMAN 94 NVVKRFKGHEHeITKVACIPKSSQFFSASRDRMVMMWD 131 67889****555999995555555568999*******9 PP == domain 3 score: 28.0 bits; conditional E-value: 1.7e-07 EEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 + + l GH vt+la+spd++ l++Gs+D+t+ +Wd sp|Q8NA23|WDR31_HUMAN 138 PRQQLCGH-AmvVTGLAVSPDSSQLCTGSRDNTLLLWD 174 667788**.6668************************9 PP == domain 4 score: 14.4 bits; conditional E-value: 0.0033 EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 13 vtslafspdgawla.sGsdDgtvriWd 38 vt+l++ p ++++ + s+D+t+r+Wd sp|Q8NA23|WDR31_HUMAN 191 VTHLCWVPREPYILqT-SEDKTLRLWD 216 8*************77.66*******9 PP == domain 5 score: 16.9 bits; conditional E-value: 0.00054 EEEEESS.SSE.EEEEEETTSSE..........EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssv.tslafspdgaw..........lasGsdDgtvriWd 38 + +++GH + v +++ + +a++s D++v+iW+ sp|Q8NA23|WDR31_HUMAN 271 ICEYKGHfQTVaSCV-------FlpralalmplIATSSHDCKVKIWN 310 56799**77796666.......44555556887788888*******8 PP >> tr|Q6NZ53|Q6NZ53_HUMAN THO complex subunit 3 OS=Homo sapiens GN=THOC3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.1 5.8e-05 0.0047 4 36 .. 48 81 .. 40 82 .. 0.83 2 ! 25.8 0.3 8.2e-07 6.7e-05 6 38 .] 94 128 .. 89 128 .. 0.84 3 ? 9.1 0.0 0.15 12 13 34 .. 145 165 .. 132 169 .. 0.75 4 ! 23.6 0.0 4e-06 0.00032 2 38 .] 215 252 .. 214 252 .. 0.91 5 ? 12.1 0.1 0.017 1.4 12 33 .. 268 289 .. 257 290 .. 0.81 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 5.8e-05 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvri 36 +r++ +Hs v+s+a+s dg+ lasGs D+t + tr|Q6NZ53|Q6NZ53_HUMAN 48 TREFLAHSAkVHSVAWSCDGRRLASGSFDKTASV 81 5677788336*****************9**9765 PP == domain 2 score: 25.8 bits; conditional E-value: 8.2e-07 EEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++GH +sv l+++p+++ l +++s D+t+riWd tr|Q6NZ53|Q6NZ53_HUMAN 94 NYRGHgDSVDQLCWHPSNPDLfVTASGDKTIRIWD 128 599**888*****99999997346666*******9 PP == domain 3 score: 9.1 bits; conditional E-value: 0.15 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 + +++spdg+ +a G +D v tr|Q6NZ53|Q6NZ53_HUMAN 145 I-NICWSPDGQTIAVGNKDDVV 165 6.789***********988766 PP == domain 4 score: 23.6 bits; conditional E-value: 4e-06 EEEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 ++++++ +H +++ +++f+p g+++a+Gs D v +Wd tr|Q6NZ53|Q6NZ53_HUMAN 215 KPVQSINAHpsNCI-CIKFDPMGKYFATGSADALVSLWD 252 6899999**95558.***********************9 PP == domain 5 score: 12.1 bits; conditional E-value: 0.017 SEEEEEEETTSSEEEEEETTSE CS WD40 12 svtslafspdgawlasGsdDgt 33 +v+ l+fs+dg++las+s+D+ tr|Q6NZ53|Q6NZ53_HUMAN 268 PVRTLSFSHDGKMLASASEDHF 289 389999**************96 PP >> tr|H7BY83|H7BY83_HUMAN WD repeat-containing protein 44 (Fragment) OS=Homo sapiens GN=WDR44 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.1 9.7e-05 0.0079 9 37 .. 409 438 .. 400 438 .. 0.87 2 ! 22.1 0.1 1.2e-05 0.00098 3 37 .. 499 533 .. 497 534 .. 0.85 3 ! 20.2 0.1 4.9e-05 0.004 2 38 .] 539 576 .. 538 576 .. 0.83 4 ? 6.3 0.0 1.2 94 9 38 .] 590 620 .. 582 620 .. 0.85 5 ! 15.3 0.1 0.0017 0.14 13 38 .] 690 714 .. 675 714 .. 0.74 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 9.7e-05 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 H + v+ ++fs+ g++las++ D+ vriW tr|H7BY83|H7BY83_HUMAN 409 EHmGAVWTMKFSHCGRLLASAGQDNVVRIW 438 47888************************* PP == domain 2 score: 22.1 bits; conditional E-value: 1.2e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +++GH + +l++s++ +l+ +s+D+tvr+W tr|H7BY83|H7BY83_HUMAN 499 PFCKYKGHtADLLDLSWSKNYFLLS-SSMDKTVRLW 533 56689***88899*******99985.666******* PP == domain 3 score: 20.2 bits; conditional E-value: 4.9e-05 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +cl + H ++vt++af+p + ++sGs Dg++r+W+ tr|H7BY83|H7BY83_HUMAN 539 ECLCCF-QHiDFVTAIAFHPRDDRyFLSGSLDGKLRLWN 576 677777.59999*****7666666688***********8 PP == domain 4 score: 6.3 bits; conditional E-value: 1.2 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 G+ + +t+ f+++g++ + G++Dg + ++d tr|H7BY83|H7BY83_HUMAN 590 GQtKLITAANFCQNGKYAVIGTYDGRCIFYD 620 6634499999*******999*99***99987 PP == domain 5 score: 15.3 bits; conditional E-value: 0.0017 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +fs+d ++l+sGs+D+ v+iW+ tr|H7BY83|H7BY83_HUMAN 690 I-KASFSHDFTYLVSGSEDKYVYIWS 714 3.3459*******************5 PP >> tr|G3V195|G3V195_HUMAN Echinoderm microtubule associated protein like 3, isoform CRA_c OS=Homo sapiens GN=EML3 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.2 4.9e-06 0.0004 4 38 .] 81 126 .. 78 126 .. 0.80 2 ? 5.1 0.4 2.9 2.4e+02 15 38 .] 193 216 .. 160 216 .. 0.74 3 ? 8.7 0.0 0.21 17 9 37 .. 295 324 .. 288 324 .. 0.87 4 ! 19.2 0.3 9.9e-05 0.008 7 38 .] 376 408 .. 372 408 .. 0.88 5 ? 10.6 0.0 0.052 4.2 16 37 .. 469 490 .. 456 491 .. 0.86 6 ! 18.9 0.7 0.00012 0.0098 9 38 .] 507 537 .. 499 537 .. 0.86 7 ! 17.8 0.4 0.00028 0.023 3 37 .. 614 650 .. 612 651 .. 0.90 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 4.9e-06 EEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 +r+++GH ++v++la++pdg +asG + + v+iWd tr|G3V195|G3V195_HUMAN 81 QRHYRGHtDCVRCLAVHPDGVRVASGqtaGVdkdgkplQPVVHIWD 126 89*****777**************9874432466778888888887 PP == domain 2 score: 5.1 bits; conditional E-value: 2.9 EEE.EETTSSEEEEEETTSEEEEEE CS WD40 15 sla.fspdgawlasGsdDgtvriWd 38 ++ +++d++ +++++ + +v++W+ tr|G3V195|G3V195_HUMAN 193 AVGfNPRDSSCIVTSG-KSHVHFWN 216 3334566777799999.*******8 PP == domain 3 score: 8.7 bits; conditional E-value: 0.21 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +s+ +l+ +dg+ l+ G++D+ + W tr|G3V195|G3V195_HUMAN 295 AHeGSIFALCLRRDGTVLSGGGRDRRLVQW 324 68888************97678****9999 PP == domain 4 score: 19.2 bits; conditional E-value: 9.9e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH + ++l+++p+++ +++++ D+ + +Wd tr|G3V195|G3V195_HUMAN 376 IQGHtDELWGLCTHPSQNRFLTCGHDRQLCLWD 408 56**666************998877*******9 PP == domain 5 score: 10.6 bits; conditional E-value: 0.052 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +++spdg +la Gs D+ ++i+ tr|G3V195|G3V195_HUMAN 469 VRYSPDGLYLAIGSHDNVIYIY 490 569**********99*****98 PP == domain 6 score: 18.9 bits; conditional E-value: 0.00012 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH s++t+l++s+dg++++s s D + Wd tr|G3V195|G3V195_HUMAN 507 GHsSFITHLDWSKDGNFIMSNSGDYEILYWD 537 9*777*************97555*****998 PP == domain 7 score: 17.8 bits; conditional E-value: 0.00028 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriW 37 + r + GH s+vts++f +d + l+s G++D ++ W tr|G3V195|G3V195_HUMAN 614 PSRMYGGHgSHVTSVRFTHDDSHLVSlGGKDASIFQW 650 67889***999*****9999999998899*****999 PP >> tr|F8W717|F8W717_HUMAN Echinoderm microtubule-associated protein-like 1 OS=Homo sapiens GN=EML1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.6 4.8e-05 0.0039 2 38 .] 250 297 .. 249 297 .. 0.79 2 ? 5.2 0.6 2.7 2.2e+02 12 38 .] 313 345 .. 301 345 .. 0.65 3 ? 9.4 0.0 0.12 9.8 11 37 .. 407 432 .. 395 432 .. 0.84 4 ? 8.7 0.0 0.21 17 9 37 .. 446 475 .. 437 476 .. 0.86 5 ? 12.0 0.5 0.018 1.5 8 38 .] 528 559 .. 516 559 .. 0.79 6 ? 12.4 0.0 0.014 1.1 16 37 .. 620 641 .. 603 641 .. 0.81 7 ! 17.3 0.7 0.0004 0.033 4 37 .. 653 687 .. 650 688 .. 0.83 8 ! 21.1 0.6 2.5e-05 0.0021 3 37 .. 764 800 .. 762 801 .. 0.83 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 4.8e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE.....ET.....TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG.....sd.....DgtvriWd 38 q++r++ GH ++v +la++pd +a+G s+ ++vriWd tr|F8W717|F8W717_HUMAN 250 QLQRHYAGHnDDVKCLAVHPDRITIATGqvagtSKdgkqlPPHVRIWD 297 89*******666*************99755433335667788888887 PP == domain 2 score: 5.2 bits; conditional E-value: 2.7 S..EEEEEEETTSSE..EEEE..ETTSEEEEEE CS WD40 12 s..vtslafspdgaw..lasG..sdDgtvriWd 38 + vt++afs+++ l++ s D+ + +Wd tr|F8W717|F8W717_HUMAN 313 DraVTCIAFSKSNGGtnLCAVddSNDHVLSVWD 345 3569***955555555586554445*******8 PP == domain 3 score: 9.4 bits; conditional E-value: 0.12 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 ++v ++ fs +g+ + +G+ g++ +W tr|F8W717|F8W717_HUMAN 407 KFVLCVTFSENGDTI-TGDSSGNILVW 432 3499**********8.7*66******* PP == domain 4 score: 8.7 bits; conditional E-value: 0.21 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +++ +l+ +dg++++ G++D+++ W tr|F8W717|F8W717_HUMAN 446 AHeGGIFALCMLRDGTLVSGGGKDRKLISW 475 79888************97668****9988 PP == domain 5 score: 12.0 bits; conditional E-value: 0.018 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + ++la + +++ +++++ D++ +Wd tr|F8W717|F8W717_HUMAN 528 QGHtDELWGLAIHASKSQFLTCGHDKHATLWD 559 59*666*****8888888777766*******9 PP == domain 6 score: 12.4 bits; conditional E-value: 0.014 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +++spdg++la Gs D+ ++i+ tr|F8W717|F8W717_HUMAN 620 MRYSPDGNFLAIGSHDNCIYIY 641 458**********99****997 PP == domain 7 score: 17.3 bits; conditional E-value: 0.0004 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++++GH s++t+l++s ++++l+s s D + W tr|F8W717|F8W717_HUMAN 653 VGKCSGHsSFITHLDWSVNSQFLVSNSGDYEILYW 687 56789**777*************975559888877 PP == domain 8 score: 21.1 bits; conditional E-value: 2.5e-05 EEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 + +++ GH s+vt ++ + d++++++G++D +++ W tr|F8W717|F8W717_HUMAN 764 PSHIYGGHsSHVTNVDfLCEDSHLISTGGKDTSIMQW 800 789*****888****966666666779********** PP >> sp|Q6UXN9|WDR82_HUMAN WD repeat-containing protein 82 OS=Homo sapiens GN=WDR82 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.0 5.1e-06 0.00041 6 38 .] 16 49 .. 9 49 .. 0.88 2 ! 25.6 0.0 9.1e-07 7.4e-05 4 38 .] 100 135 .. 97 135 .. 0.90 3 ? 3.9 0.0 6.7 5.4e+02 14 32 .. 198 215 .. 185 222 .. 0.81 4 ! 21.0 0.0 2.6e-05 0.0021 4 38 .] 229 267 .. 226 267 .. 0.84 5 ? 5.0 0.0 3 2.4e+02 10 27 .. 281 299 .. 272 304 .. 0.73 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 5.1e-06 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++ s+ +++++fsp+g ++s+sdD ++ ++d sp|Q6UXN9|WDR82_HUMAN 16 VFRENSDkINCFDFSPNGETVISSSDDDSIVLYD 49 67777456***********************998 PP == domain 2 score: 25.6 bits; conditional E-value: 9.1e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r + GH + v +l+ sp + ++sGs D+t+r+Wd sp|Q6UXN9|WDR82_HUMAN 100 IRYFPGHsKRVVALSMSPVDDTFISGSLDKTIRLWD 135 67799**77799***9******9************9 PP == domain 3 score: 3.9 bits; conditional E-value: 6.7 EEEEEETTSSEEEEEETTS CS WD40 14 tslafspdgawlasGsdDg 32 t+l+fs dg++++ ++ +g sp|Q6UXN9|WDR82_HUMAN 198 TGLKFSNDGKLILIST-NG 215 89*********98766.44 PP == domain 4 score: 21.0 bits; conditional E-value: 2.6e-05 EEEEESS.SS..E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss..v.tslafspdgawlasGsdDgtvriWd 38 ++t+ G +s v +f pd+++++ Gs+Dg++++W+ sp|Q6UXN9|WDR82_HUMAN 229 MHTFGGYaNSkaVtLEASFTPDSQFIMIGSEDGKIHVWN 267 789998886677844777********************8 PP == domain 5 score: 5.0 bits; conditional E-value: 3 S.SSEEEEEEETTSSEEEE CS WD40 10 H.ssvtslafspdgawlas 27 H +++t+l+f+p +as sp|Q6UXN9|WDR82_HUMAN 281 HtGPITCLQFNPKFMTFAS 299 6677****99997666665 PP >> sp|O00423|EMAL1_HUMAN Echinoderm microtubule-associated protein-like 1 OS=Homo sapiens GN=EML1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.6 4.9e-05 0.0039 2 38 .] 262 309 .. 261 309 .. 0.79 2 ? 5.1 0.6 2.7 2.2e+02 12 38 .] 325 357 .. 313 357 .. 0.65 3 ? 9.4 0.0 0.12 10 11 37 .. 419 444 .. 407 444 .. 0.84 4 ? 8.7 0.0 0.21 17 9 37 .. 458 487 .. 449 488 .. 0.86 5 ? 12.0 0.5 0.019 1.5 8 38 .] 540 571 .. 528 571 .. 0.79 6 ? 12.4 0.0 0.014 1.1 16 37 .. 632 653 .. 615 653 .. 0.81 7 ! 17.3 0.7 0.00041 0.033 4 37 .. 665 699 .. 662 700 .. 0.83 8 ! 21.0 0.6 2.6e-05 0.0021 3 37 .. 776 812 .. 774 813 .. 0.83 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 4.9e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE.....ET.....TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG.....sd.....DgtvriWd 38 q++r++ GH ++v +la++pd +a+G s+ ++vriWd sp|O00423|EMAL1_HUMAN 262 QLQRHYAGHnDDVKCLAVHPDRITIATGqvagtSKdgkqlPPHVRIWD 309 89*******666*************99755433335667788888887 PP == domain 2 score: 5.1 bits; conditional E-value: 2.7 S..EEEEEEETTSSE..EEEE..ETTSEEEEEE CS WD40 12 s..vtslafspdgaw..lasG..sdDgtvriWd 38 + vt++afs+++ l++ s D+ + +Wd sp|O00423|EMAL1_HUMAN 325 DraVTCIAFSKSNGGtnLCAVddSNDHVLSVWD 357 3569***955555555586554445*******8 PP == domain 3 score: 9.4 bits; conditional E-value: 0.12 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 ++v ++ fs +g+ + +G+ g++ +W sp|O00423|EMAL1_HUMAN 419 KFVLCVTFSENGDTI-TGDSSGNILVW 444 3499**********8.7*66******* PP == domain 4 score: 8.7 bits; conditional E-value: 0.21 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +++ +l+ +dg++++ G++D+++ W sp|O00423|EMAL1_HUMAN 458 AHeGGIFALCMLRDGTLVSGGGKDRKLISW 487 79888************97668****9988 PP == domain 5 score: 12.0 bits; conditional E-value: 0.019 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + ++la + +++ +++++ D++ +Wd sp|O00423|EMAL1_HUMAN 540 QGHtDELWGLAIHASKSQFLTCGHDKHATLWD 571 59*666*****8888888777766*******9 PP == domain 6 score: 12.4 bits; conditional E-value: 0.014 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +++spdg++la Gs D+ ++i+ sp|O00423|EMAL1_HUMAN 632 MRYSPDGNFLAIGSHDNCIYIY 653 458**********99****997 PP == domain 7 score: 17.3 bits; conditional E-value: 0.00041 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++++GH s++t+l++s ++++l+s s D + W sp|O00423|EMAL1_HUMAN 665 VGKCSGHsSFITHLDWSVNSQFLVSNSGDYEILYW 699 56789**777*************975559888877 PP == domain 8 score: 21.0 bits; conditional E-value: 2.6e-05 EEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 + +++ GH s+vt ++ + d++++++G++D +++ W sp|O00423|EMAL1_HUMAN 776 PSHIYGGHsSHVTNVDfLCEDSHLISTGGKDTSIMQW 812 789*****888****966666666779********** PP >> sp|Q5JSH3|WDR44_HUMAN WD repeat-containing protein 44 OS=Homo sapiens GN=WDR44 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.1 0.00011 0.0091 9 37 .. 509 538 .. 500 538 .. 0.87 2 ! 21.9 0.1 1.4e-05 0.0011 3 37 .. 599 633 .. 597 634 .. 0.85 3 ! 20.0 0.1 5.7e-05 0.0046 2 38 .] 639 676 .. 638 676 .. 0.83 4 ? 6.1 0.0 1.4 1.1e+02 9 38 .] 690 720 .. 683 720 .. 0.84 5 ! 15.1 0.1 0.002 0.16 13 38 .] 790 814 .. 775 814 .. 0.74 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 0.00011 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 H + v+ ++fs+ g++las++ D+ vriW sp|Q5JSH3|WDR44_HUMAN 509 EHmGAVWTMKFSHCGRLLASAGQDNVVRIW 538 47888************************* PP == domain 2 score: 21.9 bits; conditional E-value: 1.4e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +++GH + +l++s++ +l+ +s+D+tvr+W sp|Q5JSH3|WDR44_HUMAN 599 PFCKYKGHtADLLDLSWSKNYFLLS-SSMDKTVRLW 633 56689***88899*******99985.666******* PP == domain 3 score: 20.0 bits; conditional E-value: 5.7e-05 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +cl + H ++vt++af+p + ++sGs Dg++r+W+ sp|Q5JSH3|WDR44_HUMAN 639 ECLCCF-QHiDFVTAIAFHPRDDRyFLSGSLDGKLRLWN 676 677777.59999*****7666666688***********8 PP == domain 4 score: 6.1 bits; conditional E-value: 1.4 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 G+ + +t+ f+++g++ + G++Dg + ++d sp|Q5JSH3|WDR44_HUMAN 690 GQtKLITAANFCQNGKYAVIGTYDGRCIFYD 720 6634499999*******999*99***99987 PP == domain 5 score: 15.1 bits; conditional E-value: 0.002 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +fs+d ++l+sGs+D+ v+iW+ sp|Q5JSH3|WDR44_HUMAN 790 I-KASFSHDFTYLVSGSEDKYVYIWS 814 3.3459*******************5 PP >> sp|O00423-3|EMAL1_HUMAN Isoform 3 of Echinoderm microtubule-associated protein-like 1 OS=Homo sapiens GN=EML1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.6 5e-05 0.004 2 38 .] 281 328 .. 280 328 .. 0.79 2 ? 5.1 0.6 2.8 2.3e+02 12 38 .] 344 376 .. 332 376 .. 0.65 3 ? 9.4 0.0 0.13 10 11 37 .. 438 463 .. 426 463 .. 0.84 4 ? 8.6 0.0 0.22 17 9 37 .. 477 506 .. 468 507 .. 0.86 5 ? 12.0 0.5 0.019 1.6 8 38 .] 559 590 .. 547 590 .. 0.79 6 ? 12.4 0.0 0.014 1.2 16 37 .. 651 672 .. 634 672 .. 0.81 7 ! 17.2 0.7 0.00042 0.034 4 37 .. 684 718 .. 681 719 .. 0.83 8 ! 21.0 0.6 2.7e-05 0.0022 3 37 .. 795 831 .. 793 832 .. 0.83 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 5e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE.....ET.....TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG.....sd.....DgtvriWd 38 q++r++ GH ++v +la++pd +a+G s+ ++vriWd sp|O00423-3|EMAL1_HUMAN 281 QLQRHYAGHnDDVKCLAVHPDRITIATGqvagtSKdgkqlPPHVRIWD 328 89*******666*************99755433335667788888887 PP == domain 2 score: 5.1 bits; conditional E-value: 2.8 S..EEEEEEETTSSE..EEEE..ETTSEEEEEE CS WD40 12 s..vtslafspdgaw..lasG..sdDgtvriWd 38 + vt++afs+++ l++ s D+ + +Wd sp|O00423-3|EMAL1_HUMAN 344 DraVTCIAFSKSNGGtnLCAVddSNDHVLSVWD 376 3569***955555555586554445*******8 PP == domain 3 score: 9.4 bits; conditional E-value: 0.13 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 ++v ++ fs +g+ + +G+ g++ +W sp|O00423-3|EMAL1_HUMAN 438 KFVLCVTFSENGDTI-TGDSSGNILVW 463 3499**********8.7*66******* PP == domain 4 score: 8.6 bits; conditional E-value: 0.22 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +++ +l+ +dg++++ G++D+++ W sp|O00423-3|EMAL1_HUMAN 477 AHeGGIFALCMLRDGTLVSGGGKDRKLISW 506 79888************97668****9988 PP == domain 5 score: 12.0 bits; conditional E-value: 0.019 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + ++la + +++ +++++ D++ +Wd sp|O00423-3|EMAL1_HUMAN 559 QGHtDELWGLAIHASKSQFLTCGHDKHATLWD 590 59*666*****8888888777766*******9 PP == domain 6 score: 12.4 bits; conditional E-value: 0.014 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +++spdg++la Gs D+ ++i+ sp|O00423-3|EMAL1_HUMAN 651 MRYSPDGNFLAIGSHDNCIYIY 672 458**********99****997 PP == domain 7 score: 17.2 bits; conditional E-value: 0.00042 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++++GH s++t+l++s ++++l+s s D + W sp|O00423-3|EMAL1_HUMAN 684 VGKCSGHsSFITHLDWSVNSQFLVSNSGDYEILYW 718 56789**777*************975559888877 PP == domain 8 score: 21.0 bits; conditional E-value: 2.7e-05 EEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 + +++ GH s+vt ++ + d++++++G++D +++ W sp|O00423-3|EMAL1_HUMAN 795 PSHIYGGHsSHVTNVDfLCEDSHLISTGGKDTSIMQW 831 789*****888****966666666779********** PP >> tr|F5GZ90|F5GZ90_HUMAN Denticleless protein homolog OS=Homo sapiens GN=DTL PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.1 0.0087 0.71 2 38 .] 47 84 .. 46 84 .. 0.83 2 ! 22.1 0.1 1.2e-05 0.00098 1 38 [] 88 127 .. 88 127 .. 0.89 3 ! 14.1 0.0 0.004 0.33 12 38 .] 176 202 .. 168 202 .. 0.86 4 ! 17.0 0.0 0.0005 0.041 3 38 .] 265 303 .. 263 303 .. 0.90 5 ! 25.7 0.5 8.7e-07 7.1e-05 2 37 .. 309 346 .. 308 347 .. 0.86 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0087 EEEEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 +c +++ +H + v +la+ p l+++ + D+t ++Wd tr|F5GZ90|F5GZ90_HUMAN 47 KCFKEWMAHwNAVFDLAWVPGELKLVTAaG-DQTAKFWD 84 68888889*999****87777777887636.*******9 PP == domain 2 score: 22.1 bits; conditional E-value: 1.2e-05 TEEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 g++++t++GH +s s+afs+ + ++ +G++Dg++++Wd tr|F5GZ90|F5GZ90_HUMAN 88 GELIGTCKGHqCSLKSVAFSKFEKAVFcTGGRDGNIMVWD 127 57899*****999*****999999975499*********9 PP == domain 3 score: 14.1 bits; conditional E-value: 0.004 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 svt + f+++++++++G Dg +++Wd tr|F5GZ90|F5GZ90_HUMAN 176 SVTVVLFQDENTLVSAGAVDGIIKVWD 202 5777889999999999999*******9 PP == domain 4 score: 17.0 bits; conditional E-value: 0.0005 EEEEEESS.SS...E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ss...v.tslafspdgawlasGsdDgtvriWd 38 ++ ++ GH +s v +sl spd ++l+sGs D +iW+ tr|F5GZ90|F5GZ90_HUMAN 265 PVAIFNGHqNStfyVkSSL--SPDDQFLVSGSSDEAAYIWK 303 7899****97789999999..**********98**999995 PP == domain 5 score: 25.7 bits; conditional E-value: 8.7e-07 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 q+ ++l GH + vts++++p+ +a++sdD+t++iW tr|F5GZ90|F5GZ90_HUMAN 309 QPPTVLLGHsQEVTSVCWCPSDFTkIATCSDDNTLKIW 346 6778899**666****99999888889*********** PP >> sp|Q9NZJ0|DTL_HUMAN Denticleless protein homolog OS=Homo sapiens GN=DTL PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.9 0.1 0.0094 0.76 2 38 .] 89 126 .. 88 126 .. 0.83 2 ! 22.0 0.1 1.3e-05 0.0011 1 38 [] 130 169 .. 130 169 .. 0.89 3 ! 14.0 0.0 0.0043 0.35 12 38 .] 218 244 .. 210 244 .. 0.86 4 ! 16.9 0.0 0.00054 0.044 3 38 .] 307 345 .. 305 345 .. 0.90 5 ! 25.6 0.5 9.4e-07 7.6e-05 2 37 .. 351 388 .. 350 389 .. 0.86 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.0094 EEEEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 +c +++ +H + v +la+ p l+++ + D+t ++Wd sp|Q9NZJ0|DTL_HUMAN 89 KCFKEWMAHwNAVFDLAWVPGELKLVTAaG-DQTAKFWD 126 68888889*999****87777777887636.*******9 PP == domain 2 score: 22.0 bits; conditional E-value: 1.3e-05 TEEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 g++++t++GH +s s+afs+ + ++ +G++Dg++++Wd sp|Q9NZJ0|DTL_HUMAN 130 GELIGTCKGHqCSLKSVAFSKFEKAVFcTGGRDGNIMVWD 169 57899*****999*****999999975499*********9 PP == domain 3 score: 14.0 bits; conditional E-value: 0.0043 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 svt + f+++++++++G Dg +++Wd sp|Q9NZJ0|DTL_HUMAN 218 SVTVVLFQDENTLVSAGAVDGIIKVWD 244 5777889999999999999*******9 PP == domain 4 score: 16.9 bits; conditional E-value: 0.00054 EEEEEESS.SS...E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ss...v.tslafspdgawlasGsdDgtvriWd 38 ++ ++ GH +s v +sl spd ++l+sGs D +iW+ sp|Q9NZJ0|DTL_HUMAN 307 PVAIFNGHqNStfyVkSSL--SPDDQFLVSGSSDEAAYIWK 345 7899****97789999999..**********98**999995 PP == domain 5 score: 25.6 bits; conditional E-value: 9.4e-07 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 q+ ++l GH + vts++++p+ +a++sdD+t++iW sp|Q9NZJ0|DTL_HUMAN 351 QPPTVLLGHsQEVTSVCWCPSDFTkIATCSDDNTLKIW 388 6778899**666****99999888889*********** PP >> sp|Q676U5-4|A16L1_HUMAN Isoform 4 of Autophagy-related protein 16-1 OS=Homo sapiens GN=ATG16L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.2 0.014 1.2 6 37 .. 173 214 .. 169 215 .. 0.76 2 ! 27.0 0.1 3.4e-07 2.7e-05 3 38 .] 221 257 .. 219 257 .. 0.91 3 ? 10.8 0.2 0.044 3.6 8 38 .] 269 296 .. 261 296 .. 0.62 4 ? 5.5 0.0 2.2 1.8e+02 13 37 .. 312 336 .. 304 337 .. 0.89 5 ! 19.4 0.1 8.8e-05 0.0071 13 38 .] 358 383 .. 344 383 .. 0.85 6 ! 14.1 0.4 0.004 0.32 8 32 .. 395 420 .. 387 425 .. 0.74 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEESS.SS.........EEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ss.........vtslafspdgawlasGsdDgtvriW 37 ++++H + +ts+ f++ g++l+++s D riW sp|Q676U5-4|A16L1_HUMAN 173 VFDAHdGEvnavqfspgITSIEFDSAGSYLLAASNDFASRIW 214 6778843344455555677777********99999******* PP == domain 2 score: 27.0 bits; conditional E-value: 3.4e-07 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + +tltGHs+ v s +f d+a ++sGs D+t+++Wd sp|Q676U5-4|A16L1_HUMAN 221 LRHTLTGHSGkVLSAKFLLDNARIVSGSHDRTLKLWD 257 5699****556****************99*******9 PP == domain 3 score: 10.8 bits; conditional E-value: 0.044 ESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvriWd 38 G +++ + + ++sG+ D+++r+Wd sp|Q676U5-4|A16L1_HUMAN 269 AGSscNDIVCT-----EQCVMSGHFDKKIRFWD 296 45543343222.....233679*99*******9 PP == domain 4 score: 5.5 bits; conditional E-value: 2.2 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +t+l+ +p+ + l+s+s+D +++ sp|Q676U5-4|A16L1_HUMAN 312 ITALDLNPERTELLSCSRDDLLKVI 336 99*****************999985 PP == domain 5 score: 19.4 bits; conditional E-value: 8.8e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 t + fspdg+++a+Gs g+++iW+ sp|Q676U5-4|A16L1_HUMAN 358 WTRVVFSPDGSYVAAGSAEGSLYIWS 383 68999********************5 PP == domain 6 score: 14.1 bits; conditional E-value: 0.004 ESS.SSEEEEEEETTSSEEEEEETTS CS WD40 8 tGH.ssvtslafspdgawlasGsdDg 32 + H ss++++a+sp+g+ ++s ++ + sp|Q676U5-4|A16L1_HUMAN 395 KQHsSSINAVAWSPSGSHVVSVDKGC 420 379788************99755444 PP >> tr|C9JIS1|C9JIS1_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (Fragment) OS=Homo sapiens G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 0.0 1.1e-06 8.8e-05 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 13.0 0.1 0.0089 0.72 12 37 .. 99 124 .. 86 125 .. 0.84 3 ! 20.6 0.2 3.7e-05 0.003 4 38 .] 136 170 .. 133 170 .. 0.90 4 ! 24.5 0.1 2.1e-06 0.00017 7 38 .] 180 212 .. 174 212 .. 0.87 5 ? 5.2 0.0 2.6 2.1e+02 3 16 .. 218 232 .] 216 232 .] 0.90 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 1.1e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd tr|C9JIS1|C9JIS1_HUMAN 48 RRTLRGHlAKIYAMHWGTDSRLLVSASQDGKLIIWD 83 689****999*************************9 PP == domain 2 score: 13.0 bits; conditional E-value: 0.0089 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +v +a+ p+g+++a+G+ D+ + i+ tr|C9JIS1|C9JIS1_HUMAN 99 WVMTCAYAPSGNFVACGGLDNICSIY 124 488889*****************998 PP == domain 3 score: 20.6 bits; conditional E-value: 3.7e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + ++++f +d++ ++s++ D t+ +Wd tr|C9JIS1|C9JIS1_HUMAN 136 SRELPGHtGYLSCCRFLDDNQIITSSG-DTTCALWD 170 57899**666*************9999.*******9 PP == domain 4 score: 24.5 bits; conditional E-value: 2.1e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH ++v sl+ pdg+ ++sG D ++++Wd tr|C9JIS1|C9JIS1_HUMAN 180 FAGHsGDVMSLSLAPDGRTFVSGACDASIKLWD 212 78**777****************77*******9 PP == domain 5 score: 5.2 bits; conditional E-value: 2.6 EEEEEESS.SSEEEE CS WD40 3 clrtltGH.ssvtsl 16 c +t+ GH s+++++ tr|C9JIS1|C9JIS1_HUMAN 218 CRQTFIGHeSDINAV 232 889*****999**99 PP >> sp|Q32P44|EMAL3_HUMAN Echinoderm microtubule-associated protein-like 3 OS=Homo sapiens GN=EML3 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.2 6.9e-06 0.00056 4 38 .] 298 343 .. 295 343 .. 0.80 2 ? 4.7 0.2 3.7 3e+02 15 38 .] 410 433 .. 382 433 .. 0.73 3 ? 8.2 0.0 0.29 23 9 37 .. 512 541 .. 505 541 .. 0.87 4 ! 18.8 0.3 0.00014 0.011 7 38 .] 593 625 .. 589 625 .. 0.88 5 ? 10.2 0.0 0.072 5.8 16 37 .. 686 707 .. 673 708 .. 0.86 6 ! 18.5 0.7 0.00017 0.014 9 38 .] 724 754 .. 716 754 .. 0.86 7 ! 17.3 0.4 0.00039 0.032 3 37 .. 831 867 .. 829 868 .. 0.90 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 6.9e-06 EEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 +r+++GH ++v++la++pdg +asG + + v+iWd sp|Q32P44|EMAL3_HUMAN 298 QRHYRGHtDCVRCLAVHPDGVRVASGqtaGVdkdgkplQPVVHIWD 343 89*****777**************9874432466778888888887 PP == domain 2 score: 4.7 bits; conditional E-value: 3.7 EEE.EETTSSEEEEEETTSEEEEEE CS WD40 15 sla.fspdgawlasGsdDgtvriWd 38 ++ +++d++ +++++ + +v++W+ sp|Q32P44|EMAL3_HUMAN 410 AVGfNPRDSSCIVTSG-KSHVHFWN 433 3434566777799999.*******8 PP == domain 3 score: 8.2 bits; conditional E-value: 0.29 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +s+ +l+ +dg+ l+ G++D+ + W sp|Q32P44|EMAL3_HUMAN 512 AHeGSIFALCLRRDGTVLSGGGRDRRLVQW 541 68888************97678****9999 PP == domain 4 score: 18.8 bits; conditional E-value: 0.00014 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH + ++l+++p+++ +++++ D+ + +Wd sp|Q32P44|EMAL3_HUMAN 593 IQGHtDELWGLCTHPSQNRFLTCGHDRQLCLWD 625 56**666************998877*******9 PP == domain 5 score: 10.2 bits; conditional E-value: 0.072 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +++spdg +la Gs D+ ++i+ sp|Q32P44|EMAL3_HUMAN 686 VRYSPDGLYLAIGSHDNVIYIY 707 569**********99*****98 PP == domain 6 score: 18.5 bits; conditional E-value: 0.00017 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH s++t+l++s+dg++++s s D + Wd sp|Q32P44|EMAL3_HUMAN 724 GHsSFITHLDWSKDGNFIMSNSGDYEILYWD 754 9*777*************97555*****998 PP == domain 7 score: 17.3 bits; conditional E-value: 0.00039 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriW 37 + r + GH s+vts++f +d + l+s G++D ++ W sp|Q32P44|EMAL3_HUMAN 831 PSRMYGGHgSHVTSVRFTHDDSHLVSlGGKDASIFQW 867 67889***999*****9999999998899*****999 PP >> tr|B7WPE2|B7WPE2_HUMAN Echinoderm microtubule associated protein like 3, isoform CRA_e OS=Homo sapiens GN=EML3 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.2 6.9e-06 0.00056 4 38 .] 299 344 .. 296 344 .. 0.80 2 ? 4.7 0.2 3.7 3e+02 15 38 .] 411 434 .. 383 434 .. 0.73 3 ? 8.2 0.0 0.29 23 9 37 .. 513 542 .. 506 542 .. 0.87 4 ! 18.7 0.3 0.00014 0.011 7 38 .] 594 626 .. 590 626 .. 0.88 5 ? 10.2 0.0 0.072 5.8 16 37 .. 687 708 .. 674 709 .. 0.86 6 ! 18.5 0.7 0.00017 0.014 9 38 .] 725 755 .. 717 755 .. 0.86 7 ! 17.3 0.4 0.00039 0.032 3 37 .. 832 868 .. 830 869 .. 0.90 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 6.9e-06 EEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 +r+++GH ++v++la++pdg +asG + + v+iWd tr|B7WPE2|B7WPE2_HUMAN 299 QRHYRGHtDCVRCLAVHPDGVRVASGqtaGVdkdgkplQPVVHIWD 344 89*****777**************9874432466778888888887 PP == domain 2 score: 4.7 bits; conditional E-value: 3.7 EEE.EETTSSEEEEEETTSEEEEEE CS WD40 15 sla.fspdgawlasGsdDgtvriWd 38 ++ +++d++ +++++ + +v++W+ tr|B7WPE2|B7WPE2_HUMAN 411 AVGfNPRDSSCIVTSG-KSHVHFWN 434 3434566777799999.*******8 PP == domain 3 score: 8.2 bits; conditional E-value: 0.29 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +s+ +l+ +dg+ l+ G++D+ + W tr|B7WPE2|B7WPE2_HUMAN 513 AHeGSIFALCLRRDGTVLSGGGRDRRLVQW 542 68888************97678****9999 PP == domain 4 score: 18.7 bits; conditional E-value: 0.00014 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH + ++l+++p+++ +++++ D+ + +Wd tr|B7WPE2|B7WPE2_HUMAN 594 IQGHtDELWGLCTHPSQNRFLTCGHDRQLCLWD 626 56**666************998877*******9 PP == domain 5 score: 10.2 bits; conditional E-value: 0.072 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +++spdg +la Gs D+ ++i+ tr|B7WPE2|B7WPE2_HUMAN 687 VRYSPDGLYLAIGSHDNVIYIY 708 569**********99*****98 PP == domain 6 score: 18.5 bits; conditional E-value: 0.00017 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH s++t+l++s+dg++++s s D + Wd tr|B7WPE2|B7WPE2_HUMAN 725 GHsSFITHLDWSKDGNFIMSNSGDYEILYWD 755 9*777*************97555*****998 PP == domain 7 score: 17.3 bits; conditional E-value: 0.00039 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriW 37 + r + GH s+vts++f +d + l+s G++D ++ W tr|B7WPE2|B7WPE2_HUMAN 832 PSRMYGGHgSHVTSVRFTHDDSHLVSlGGKDASIFQW 868 67889***999*****9999999998899*****999 PP >> sp|Q8TAF3-4|WDR48_HUMAN Isoform 4 of WD repeat-containing protein 48 OS=Homo sapiens GN=WDR48 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 0.0 0.11 8.9 23 38 .] 7 21 .. 2 21 .. 0.71 2 ! 21.2 0.0 2.3e-05 0.0019 3 38 .] 27 63 .. 25 63 .. 0.93 3 ! 15.3 0.0 0.0017 0.14 4 38 .] 79 114 .. 76 114 .. 0.92 4 ! 24.2 0.1 2.5e-06 0.00021 4 38 .] 121 156 .. 118 156 .. 0.90 5 ? 10.8 0.1 0.045 3.7 2 35 .. 161 195 .. 160 198 .. 0.88 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.11 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 + ++s+s D tv++W+ sp|Q8TAF3-4|WDR48_HUMAN 7 Q-VISASSDTTVKVWN 21 3.455555*******8 PP == domain 2 score: 21.2 bits; conditional E-value: 2.3e-05 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 c+ tl++H++ v +la+ +d+ ++as++ D+ + +Wd sp|Q8TAF3-4|WDR48_HUMAN 27 CMSTLRTHKDyVKALAYAKDKELVASAGLDRQIFLWD 63 999*****666**************9999*******9 PP == domain 3 score: 15.3 bits; conditional E-value: 0.0017 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +l+G +s++sla ++ g+ ++sGs + +r+Wd sp|Q8TAF3-4|WDR48_HUMAN 79 TSSLSGNkDSIYSLAMNQLGTIIVSGSTEKVLRVWD 114 56899**777*************************9 PP == domain 4 score: 24.2 bits; conditional E-value: 2.5e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l+GH ++v +l ++dg+ +sGs Dgt+r+W+ sp|Q8TAF3-4|WDR48_HUMAN 121 LMKLKGHtDNVKALLLNRDGTQCLSGSSDGTIRLWS 156 7789***766****************99*******5 PP == domain 5 score: 10.8 bits; conditional E-value: 0.045 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvr 35 +c+ t++ H +v++l++++ + + sG++D++++ sp|Q8TAF3-4|WDR48_HUMAN 161 RCIATYRVHdEGVWALQVNDAFTHVYSGGRDRKIY 195 79*******777****888888889*******996 PP >> tr|H0YF10|H0YF10_HUMAN Histone-binding protein RBBP4 (Fragment) OS=Homo sapiens GN=RBBP4 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.2 0.028 2.3 8 38 .] 27 59 .. 17 59 .. 0.69 2 ! 32.3 0.0 6.9e-09 5.6e-07 2 38 .] 67 105 .. 66 105 .. 0.90 3 ! 22.7 0.1 7.9e-06 0.00064 4 38 .] 113 149 .. 111 149 .. 0.85 4 ! 20.5 0.1 3.9e-05 0.0032 4 37 .. 170 205 .. 167 206 .. 0.85 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.028 ESSSS.EEEEEEETTSSE......EEEEE..TTSEEEEEE CS WD40 8 tGHss.vtslafspdgaw......lasGs..dDgtvriWd 38 GH+ v ++ +w l+ Gs dD++++iWd tr|H0YF10|H0YF10_HUMAN 27 PGHTAvVEDV------SWhllhesLF-GSvaDDQKLMIWD 59 3996657***......5544444488.76458*******9 PP == domain 2 score: 32.3 bits; conditional E-value: 6.9e-09 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++ ++H v++l+f+p++ ++ a+Gs D+tv +Wd tr|H0YF10|H0YF10_HUMAN 67 KPSHSVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 105 68899****777************6379**********9 PP == domain 3 score: 22.7 bits; conditional E-value: 7.9e-06 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l++++ H++ + +++sp++ ++ s++ D+ + +Wd tr|H0YF10|H0YF10_HUMAN 113 LHSFESHKDeIFQVQWSPHNETILaSSGTDRRLNVWD 149 89*****556************7525567*******9 PP == domain 4 score: 20.5 bits; conditional E-value: 3.9e-05 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ +W tr|H0YF10|H0YF10_HUMAN 170 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQVW 205 56668**666************9977799****999 PP >> tr|H0Y9R3|H0Y9R3_HUMAN WD repeat-containing protein 26 (Fragment) OS=Homo sapiens GN=WDR26 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.1 0.27 22 25 37 .. 4 16 .. 2 17 .. 0.91 2 ! 20.6 0.1 3.7e-05 0.003 2 32 .. 26 58 .. 25 65 .. 0.82 3 ! 13.5 0.0 0.0061 0.49 9 30 .. 78 100 .. 69 114 .. 0.81 4 ! 15.8 0.1 0.0012 0.094 13 37 .. 208 232 .. 193 233 .. 0.80 5 ! 27.9 0.0 1.8e-07 1.4e-05 3 37 .. 239 275 .. 237 275 .. 0.78 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.27 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 la+Gs+D tv iW tr|H0Y9R3|H0Y9R3_HUMAN 4 LATGSKDTTVIIW 16 79*********** PP == domain 2 score: 20.6 bits; conditional E-value: 3.7e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEE.TTS CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs.dDg 32 ++l+tl+GH +v+ +a+spd ++l++++ dD+ tr|H0Y9R3|H0Y9R3_HUMAN 26 KLLKTLEGHaYGVSYIAWSPDDNYLVACGpDDC 58 6899*****666**************9984444 PP == domain 3 score: 13.5 bits; conditional E-value: 0.0061 SS.SSEEEEEEETTSSEEEEEET CS WD40 9 GH.ssvtslafspdgawlasGsd 30 H +s ts+a++pdg+ +++G+ tr|H0Y9R3|H0Y9R3_HUMAN 78 SHeDSLTSVAWNPDGKRFVTGGQ 100 69888****************83 PP == domain 4 score: 15.8 bits; conditional E-value: 0.0012 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++s+ ++ +++asGs+D++v+iW tr|H0Y9R3|H0Y9R3_HUMAN 208 IHSCFGGHNEDFIASGSEDHKVYIW 232 777778889999************* PP == domain 5 score: 27.9 bits; conditional E-value: 1.8e-07 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 ++ +ltGH v++++++p + +as+sdDgtvriW tr|H0Y9R3|H0Y9R3_HUMAN 239 PIAELTGHtRTVNCVSWNPQIPSmMASASDDGTVRIW 275 57789***555****6655555555788********* PP >> tr|F5H4M2|F5H4M2_HUMAN Protein HIRA OS=Homo sapiens GN=HIRA PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 0.1 9.7e-07 7.9e-05 9 38 .] 24 54 .. 17 54 .. 0.90 2 ! 34.1 3.6 2e-09 1.6e-07 1 38 [] 77 115 .. 77 115 .. 0.95 3 ! 22.2 0.0 1.1e-05 0.00087 3 37 .. 122 157 .. 120 158 .. 0.89 4 ? 10.4 0.1 0.059 4.8 9 29 .. 177 197 .. 169 202 .. 0.79 5 ? 5.1 0.6 2.9 2.4e+02 7 37 .. 220 268 .. 214 268 .. 0.57 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 9.7e-07 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H +v+++++s +g +lasG+dD+ +++W+ tr|F5H4M2|F5H4M2_HUMAN 24 NHlACVNCVRWSNSGMYLASGGDDKLIMVWK 54 68888*************************6 PP == domain 2 score: 34.1 bits; conditional E-value: 2e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++c+ +l+ H ++v ++a+sp+ awlas+s D+tv iW+ tr|F5H4M2|F5H4M2_HUMAN 77 WRCVSILRNHsGDVMDVAWSPHDAWLASCSVDNTVVIWN 115 68********777*************************8 PP == domain 3 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriW 37 l tl+GHs+ v +l ++p g+++as dD+++++W tr|F5H4M2|F5H4M2_HUMAN 122 ILATLRGHSGlVKGLTWDPVGKYIASQADDRSLKVW 157 5789****7789***********986588******* PP == domain 4 score: 10.4 bits; conditional E-value: 0.059 SSSSEEEEEEETTSSEEEEEE CS WD40 9 GHssvtslafspdgawlasGs 29 G ++v l++spdg++l+s++ tr|F5H4M2|F5H4M2_HUMAN 177 GTTHVLRLSWSPDGHYLVSAH 197 3344**************986 PP == domain 5 score: 5.1 bits; conditional E-value: 2.9 EESS.SSEEEEE...............EETTSSE..EEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla...............fspdgaw..lasGsdDgtvriW 37 + GH + vt ++ p+ ++ a Gs+D+++ +W tr|F5H4M2|F5H4M2_HUMAN 220 FVGHrKAVTVVKfnpkifkkkqkngssAKPSCPYccCAVGSKDRSLSVW 268 5677666766655555555544444442222223324569********9 PP >> tr|F5H100|F5H100_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (Fragment) OS=Homo sapiens G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.0 9.8e-07 8e-05 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 13.6 0.0 0.0057 0.46 12 38 .] 99 125 .. 86 125 .. 0.85 3 ! 19.8 0.4 6.6e-05 0.0053 4 38 .] 136 170 .. 133 170 .. 0.90 4 ! 20.6 0.1 3.6e-05 0.0029 2 38 .] 175 212 .. 174 212 .. 0.91 5 ? 7.9 0.0 0.36 29 1 16 [. 216 232 .] 216 232 .] 0.91 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 9.8e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ +Wd tr|F5H100|F5H100_HUMAN 48 RRTLRGHlAKIYAMHWATDSKLLVSASQDGKLIVWD 83 689****999*************************9 PP == domain 2 score: 13.6 bits; conditional E-value: 0.0057 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ tr|F5H100|F5H100_HUMAN 99 WVMTCAYAPSGNFVACGGLDNMCSIYN 125 488889******************997 PP == domain 3 score: 19.8 bits; conditional E-value: 6.6e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l++H + ++++f +d++ ++s++ D t+ +Wd tr|F5H100|F5H100_HUMAN 136 SRELSAHtGYLSCCRFLDDNNIVTSSG-DTTCALWD 170 6899***666*************9989.*******9 PP == domain 4 score: 20.6 bits; conditional E-value: 3.6e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+ +++ GH ++ sla+spd ++++sG D + ++Wd tr|F5H100|F5H100_HUMAN 175 QQKTVFVGHtGDCMSLAVSPDFNLFISGACDASAKLWD 212 6678899**88899**************77*******9 PP == domain 5 score: 7.9 bits; conditional E-value: 0.36 TEEEEEEESS.SSEEEE CS WD40 1 gqclrtltGH.ssvtsl 16 g+c +t+tGH s+++++ tr|F5H100|F5H100_HUMAN 216 GTCRQTFTGHeSDINAI 232 6799******999*998 PP >> sp|Q8IV35|WDR49_HUMAN WD repeat-containing protein 49 OS=Homo sapiens GN=WDR49 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 4.7 3.8e+02 12 38 .] 21 47 .. 11 47 .. 0.85 2 ? 11.2 0.0 0.034 2.7 2 38 .] 53 90 .. 52 90 .. 0.88 3 ! 21.6 0.0 1.8e-05 0.0014 2 38 .] 181 220 .. 180 220 .. 0.85 4 ! 15.8 0.0 0.0011 0.093 10 38 .] 282 310 .. 277 310 .. 0.89 5 ? 6.3 0.0 1.2 97 22 38 .] 390 405 .. 358 405 .. 0.81 6 ? 10.5 0.0 0.056 4.5 2 38 .] 410 448 .. 409 448 .. 0.87 7 ? 6.7 0.0 0.91 73 3 36 .. 467 503 .. 465 503 .. 0.84 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 4.7 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +++++++++ +++a+++ +++v +W+ sp|Q8IV35|WDR49_HUMAN 21 GIHAFDYHSRLNLIATAGINNKVCLWN 47 5888989999999*************8 PP == domain 2 score: 11.2 bits; conditional E-value: 0.034 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++l GH sv +++f + + l+s s+D+ +r+Wd sp|Q8IV35|WDR49_HUMAN 53 KPVGVLWGHsASVIAVQFFVERKQLFSFSKDKVLRLWD 90 6788899**77788**99999999**88*********9 PP == domain 3 score: 21.6 bits; conditional E-value: 1.8e-05 EEEEEEE.SS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtlt.GH.ss.vtslafspdgawlasGsdDgtvriWd 38 q+++ +t H + ++ +a + + + l++Gs Dgtv+iWd sp|Q8IV35|WDR49_HUMAN 181 QKIKQFTgCHgNAeISTMALDANETRLLTGSTDGTVKIWD 220 67777874666558*************************9 PP == domain 4 score: 15.8 bits; conditional E-value: 0.0011 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ + af p ++++ +Gs+Dg + +W+ sp|Q8IV35|WDR49_HUMAN 282 HhDDILCAAFLPPQTLV-TGSYDGEIVLWN 310 4488************7.7**********8 PP == domain 5 score: 6.3 bits; conditional E-value: 1.2 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 +++++G+ g vr+Wd sp|Q8IV35|WDR49_HUMAN 390 ANLVSCGG-SGYVRFWD 405 35566677.*******9 PP == domain 6 score: 10.5 bits; conditional E-value: 0.056 EEEEEEESSSSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla..fspdgawlasGsdDgtvriWd 38 q+l ++ +Hs+v s+ +++ +++l++G+ Dg ++iW+ sp|Q8IV35|WDR49_HUMAN 410 QLLAEFLAHSGVGSIImsTDKMNRYLTTGDLDGWLKIWN 448 6788899998898888778888999****99*******8 PP == domain 7 score: 6.7 bits; conditional E-value: 0.91 EEEEEESS.SSEEEEE.EETTSSEEE.EEETTSEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgawla.sGsdDgtvri 36 ++r++ H + ++sl p g++l+ s+s D+++ + sp|Q8IV35|WDR49_HUMAN 467 LIRSFQPHeDRISSLEmCEPGGQLLIiSSSADCSICV 503 6789999*777****9999999998648889***976 PP >> sp|Q5TAQ9|DCAF8_HUMAN DDB1- and CUL4-associated factor 8 OS=Homo sapiens GN=DCAF8 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.9 0.5 8.6e-08 7e-06 2 38 .] 184 221 .. 183 221 .. 0.93 2 ? 5.5 0.0 2.2 1.8e+02 4 36 .. 228 264 .. 225 264 .. 0.73 3 ? 4.3 0.0 5 4.1e+02 16 38 .] 346 360 .. 333 360 .. 0.81 4 ? 8.1 0.0 0.32 26 10 38 .] 380 415 .. 372 415 .. 0.75 5 ! 15.2 0.0 0.0018 0.15 2 37 .. 423 462 .. 422 463 .. 0.89 6 ! 15.0 0.0 0.0021 0.17 8 37 .. 474 505 .. 467 505 .. 0.82 Alignments for each domain: == domain 1 score: 28.9 bits; conditional E-value: 8.6e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ l+GH ++v+ l f++ g+wlasGsdD +v +Wd sp|Q5TAQ9|DCAF8_HUMAN 184 RLQHGLEGHtGCVNTLHFNQRGTWLASGSDDLKVVVWD 221 57899****777*************************9 PP == domain 2 score: 5.5 bits; conditional E-value: 2.2 EEEE.ESS.SSEEEEE...EETTSSEEEEEETTSEEEE CS WD40 4 lrtl.tGH.ssvtsla...fspdgawlasGsdDgtvri 36 + + +GH s+v + +s d+++ + + +Dg vr+ sp|Q5TAQ9|DCAF8_HUMAN 228 VLDFeSGHkSNVFQAKflpNSGDSTLAM-CARDGQVRV 264 5555259*66697666888999999988.566****97 PP == domain 3 score: 4.3 bits; conditional E-value: 5 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 + +a G++D+ vri+d sp|Q5TAQ9|DCAF8_HUMAN 346 Q--------FAVGGRDQFVRIYD 360 2........678**********8 PP == domain 4 score: 8.1 bits; conditional E-value: 0.32 S..SS.....EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H..ss.....vtslafspdgawlasGsdDgtvriWd 38 H +s +t+l +s+dg+ l+++ D +++++ sp|Q5TAQ9|DCAF8_HUMAN 380 HlvNSeskanITCLVYSHDGTELLASYNDEDIYLFN 415 3433344567*************9998898888876 PP == domain 5 score: 15.2 bits; conditional E-value: 0.0018 EEEEEEESS.SS..EEEEE.EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ss..vtsla.fspdgawlasGsdDgtvriW 37 q ++ ++GH ++ v ++ + p + +++sGsd g++ +W sp|Q5TAQ9|DCAF8_HUMAN 423 QYVKRYKGHrNNatVKGVNfYGPKSEFVVSGSDCGHIFLW 462 56788****966799***999999999************* PP == domain 6 score: 15.0 bits; conditional E-value: 0.0021 ESSSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHss..vtslafspdgawlasGsdDgtvriW 37 +G ++ v++l +p+ + la+++ D+ v+iW sp|Q5TAQ9|DCAF8_HUMAN 474 EGDKGgvVNCLEPHPHLPVLATSGLDHDVKIW 505 55533467*************9999******* PP >> tr|H3BN58|H3BN58_HUMAN Target of rapamycin complex subunit LST8 (Fragment) OS=Homo sapiens GN=MLST8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.044 3.6 24 37 .. 14 27 .. 7 28 .. 0.82 2 ! 14.7 0.0 0.0026 0.21 3 38 .] 34 69 .. 32 69 .. 0.86 3 ! 24.3 0.1 2.4e-06 0.0002 6 38 .] 80 113 .. 75 113 .. 0.82 4 ! 21.7 0.0 1.6e-05 0.0013 2 38 .] 120 156 .. 119 156 .. 0.96 5 ? 6.1 0.0 1.4 1.1e+02 12 38 .] 172 198 .. 159 198 .. 0.83 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.044 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W tr|H3BN58|H3BN58_HUMAN 14 ILATAGYDHTVRFW 27 5888888******* PP == domain 2 score: 14.7 bits; conditional E-value: 0.0026 EEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 c+rt H s v++l + pd +++a+++ +++r++d tr|H3BN58|H3BN58_HUMAN 34 CTRTVQ-HqdSQVNALEVTPDRSMIAAAG-YQHIRMYD 69 788875.75444**************99*.******98 PP == domain 3 score: 24.3 bits; conditional E-value: 2.4e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd tr|H3BN58|H3BN58_HUMAN 80 SYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 113 5555445688999********************9 PP == domain 4 score: 21.7 bits; conditional E-value: 1.6e-05 EEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtslafspdgawlasGsdDgtvriWd 38 qc+r++ ++++++ +p++a l+ G+ g ++iWd tr|H3BN58|H3BN58_HUMAN 120 QCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWD 156 8******9999*************************9 PP == domain 5 score: 6.1 bits; conditional E-value: 1.4 SEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 12 svtslafspdgawlasG.sdDgtvriWd 38 s+ts +pd +++a+ s g++++W+ tr|H3BN58|H3BN58_HUMAN 172 SITSAHIDPDASYMAAVnS-TGNCYVWN 198 389999*******997767.*******8 PP >> sp|Q8TEB1-3|DCA11_HUMAN Isoform 3 of DDB1- and CUL4-associated factor 11 OS=Homo sapiens GN=DCAF11 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.053 4.3 18 38 .] 80 100 .. 56 100 .. 0.87 2 ? 3.7 0.1 7.9 6.4e+02 12 31 .. 120 139 .. 108 146 .. 0.75 3 ? 6.1 0.0 1.4 1.1e+02 13 38 .] 168 193 .. 150 193 .. 0.88 4 ! 17.2 0.0 0.00041 0.033 4 38 .] 198 236 .. 195 236 .. 0.75 5 ! 20.7 0.0 3.3e-05 0.0027 2 38 .] 246 283 .. 245 283 .. 0.92 6 ? 5.1 0.1 2.8 2.2e+02 4 38 .] 328 369 .. 326 369 .. 0.69 7 ! 24.3 0.5 2.4e-06 0.00019 3 37 .. 375 410 .. 373 411 .. 0.90 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.053 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 +s+dg+ ++s++ D+t+r++d sp|Q8TEB1-3|DCA11_HUMAN 80 YSKDGQIFMSACQDQTIRLYD 100 89*****************98 PP == domain 2 score: 3.7 bits; conditional E-value: 7.9 SEEEEEEETTSSEEE.EEETT CS WD40 12 svtslafspdgawla.sGsdD 31 sv ++af pdg+ ++ s s+ sp|Q8TEB1-3|DCA11_HUMAN 120 SVLDVAFTPDGNHFLyS-SWS 139 3889*********7535.443 PP == domain 3 score: 6.1 bits; conditional E-value: 1.4 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v s+a+s+dg+ ++ G Dg ++++d sp|Q8TEB1-3|DCA11_HUMAN 168 VFSIAVSSDGREVLGGANDGCLYVFD 193 8899**********7778*****998 PP == domain 4 score: 17.2 bits; conditional E-value: 0.00041 EEEEE..SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 4 lrtlt..GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 rtl H ++v+++af + ++ l+sG+dD +++Wd sp|Q8TEB1-3|DCA11_HUMAN 198 RRTLQieSHeDDVNAVAFADISSQiLFSGGDDAICKVWD 236 55653339*888****96666666356***********9 PP == domain 5 score: 20.7 bits; conditional E-value: 3.3e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ l GH +++t ++ d ++l+s s+D+t+++Wd sp|Q8TEB1-3|DCA11_HUMAN 246 KPVGALAGHqDGITFIDSKGDARYLISNSKDQTIKLWD 283 5788899**777**************88*********9 PP == domain 6 score: 5.1 bits; conditional E-value: 2.8 EEEEESSSSE.EEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHssv.tsla.......fspdgawlasGsdDgtvriWd 38 l t++GH +v + l s ++++ sG+ g+v ++d sp|Q8TEB1-3|DCA11_HUMAN 328 LMTYRGH-GVlHTLIrcrfspiHSTGQQFIYSGCSTGKVVVYD 369 789****.75444445555576666667788997699998887 PP == domain 7 score: 24.3 bits; conditional E-value: 2.4e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++lt H +v++++++p ++s+s+Dg++r+W sp|Q8TEB1-3|DCA11_HUMAN 375 IVKKLTNHkACVRDVSWHPFEEKIVSSSWDGNLRLW 410 578899**666************************* PP >> tr|D6RFZ9|D6RFZ9_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.3 0.19 15 5 37 .. 9 83 .. 5 84 .. 0.52 2 ! 36.7 0.6 2.9e-10 2.4e-08 3 38 .] 95 131 .. 93 131 .. 0.93 3 ! 37.1 0.2 2.2e-10 1.8e-08 3 38 .] 137 173 .. 135 173 .. 0.93 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.19 EEEESS.SSEEEEE...................EETTSSEEEE......................EET.TSEEEEE CS WD40 5 rtltGH.ssvtsla...................fspdgawlas......................Gsd.DgtvriW 37 +tl+GH ++vt +a + p ga + + Gs+ D+t+ +W tr|D6RFZ9|D6RFZ9_HUMAN 9 GTLKGHnGWVTQIAttpqfpdmilsasrvwpgaYGPGGAVM-TptchlsvgaeiqrlflscrpaqGSWgDKTIIMW 83 7899**66699999866555555333333333333333331.1333333444444444445666655557777777 PP == domain 2 score: 36.7 bits; conditional E-value: 2.9e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6RFZ9|D6RFZ9_HUMAN 95 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 131 7899****667************99***********9 PP == domain 3 score: 37.1 bits; conditional E-value: 2.2e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++v s+afs+d++ ++sGs+D+t+++W+ tr|D6RFZ9|D6RFZ9_HUMAN 137 TTRRFVGHtKDVLSVAFSSDNRQIVSGSRDKTIKLWN 173 678899******************************8 PP >> tr|H0YG67|H0YG67_HUMAN Autophagy-related protein 16-2 (Fragment) OS=Homo sapiens GN=ATG16L2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.7 0.0 4.2e-07 3.4e-05 5 38 .] 161 195 .. 158 195 .. 0.94 2 ? 10.8 0.0 0.046 3.7 5 37 .. 205 238 .. 202 239 .. 0.86 3 ! 15.9 0.0 0.0011 0.091 5 38 .] 247 281 .. 243 281 .. 0.81 4 ? 9.9 0.2 0.084 6.8 24 38 .] 306 320 .. 290 320 .. 0.81 5 ! 14.8 0.1 0.0024 0.19 7 38 .] 330 361 .. 324 361 .. 0.81 6 ? 4.4 0.7 4.9 3.9e+02 8 37 .. 388 415 .. 377 416 .] 0.81 Alignments for each domain: == domain 1 score: 26.7 bits; conditional E-value: 4.2e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++H s v++++f p++++la+G+ D+ +++W+ tr|H0YG67|H0YG67_HUMAN 161 DVLDAHlSEVNAVRFGPNSSLLATGGADRLIHLWN 195 5799**999*************************8 PP == domain 2 score: 10.8 bits; conditional E-value: 0.046 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+G +s+ts++f+p+g ++++++++ +W tr|H0YG67|H0YG67_HUMAN 205 QTLEGAgGSITSVDFDPSGYQVLAATYNQAAQLW 238 689999888************9999878888888 PP == domain 3 score: 15.9 bits; conditional E-value: 0.0011 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl+GH++ vt+ +f + ++Gs+D+tv+ Wd tr|H0YG67|H0YG67_HUMAN 247 ETLSGHKDkVTAAKFKLTRHQAVTGSRDRTVKEWD 281 589***666****66555555889**********8 PP == domain 4 score: 9.9 bits; conditional E-value: 0.084 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 ++sG+ D+++r+Wd tr|H0YG67|H0YG67_HUMAN 306 IIISGHNDQKIRFWD 320 2579**********9 PP == domain 5 score: 14.8 bits; conditional E-value: 0.0024 EESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtslafspdgawlasGsdDgtvriWd 38 + ++ vtsl+ s+d+ l+s+s+D+t+++ d tr|H0YG67|H0YG67_HUMAN 330 IPVQGRVTSLSLSHDQLHLLSCSRDNTLKVID 361 444545***********************965 PP == domain 6 score: 4.4 bits; conditional E-value: 4.9 ESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriW 37 ++ v+++a++ +g+ ++s + ++v +W tr|H0YG67|H0YG67_HUMAN 388 SAA--VNAVAWCYSGSHMVSVDQGRKVVLW 415 433..9***999999999888889999999 PP >> sp|Q13112|CAF1B_HUMAN Chromatin assembly factor 1 subunit B OS=Homo sapiens GN=CHAF1B PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.1 0.06 4.9 10 38 .] 11 45 .. 4 45 .. 0.72 2 ! 17.9 0.0 0.00025 0.021 9 38 .] 64 94 .. 57 94 .. 0.88 3 ! 29.1 0.5 7.2e-08 5.8e-06 2 38 .] 120 157 .. 119 157 .. 0.95 4 ! 15.1 0.0 0.0019 0.16 1 37 [. 161 198 .. 161 199 .. 0.86 5 ? 10.6 0.3 0.053 4.3 12 34 .. 348 370 .. 333 372 .. 0.83 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.06 S.SS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 10 H.ss.vtslafspdgaw....lasGsdDgtvriWd 38 H + v+sl+f++ a las++ D +vriW+ sp|Q13112|CAF1B_HUMAN 11 HnKEpVYSLDFQHGTAGrihrLASAGVDTNVRIWK 45 642248888544444448888899999*******6 PP == domain 2 score: 17.9 bits; conditional E-value: 0.00025 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H + v+ ++fsp g lasG+dD + +W+ sp|Q13112|CAF1B_HUMAN 64 RHtKAVNVVRFSPTGEILASGGDDAVILLWK 94 59888*99**********************6 PP == domain 3 score: 29.1 bits; conditional E-value: 7.2e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + ++tl+GH +v+++++ dg+++as+s D+t iWd sp|Q13112|CAF1B_HUMAN 120 TVVKTLRGHlEDVYDICWATDGNLMASASVDNTAIIWD 157 5689*********************************9 PP == domain 4 score: 15.1 bits; conditional E-value: 0.0019 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 gq++ ++ H s v ++ ++p g+++a+ s D+ +r++ sp|Q13112|CAF1B_HUMAN 161 GQKISIFNEHkSYVQGVTWDPLGQYVATLSCDRVLRVY 198 688999****666*************97455*****98 PP == domain 5 score: 10.6 bits; conditional E-value: 0.053 SEEEEEEETTSSEEEEEETTSEE CS WD40 12 svtslafspdgawlasGsdDgtv 34 +++++s+dga+la +s Dg + sp|Q13112|CAF1B_HUMAN 348 TLSDISWSSDGAFLAISSTDGYC 370 478999********98888*987 PP >> sp|Q8NHY2-3|RFWD2_HUMAN Isoform 3 of E3 ubiquitin-protein ligase RFWD2 OS=Homo sapiens GN=RFWD2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 4.9 4e+02 9 37 .. 195 223 .. 182 224 .. 0.81 2 ! 14.5 0.1 0.0031 0.25 10 38 .] 245 274 .. 236 274 .. 0.80 3 ! 15.4 0.0 0.0016 0.13 2 38 .] 279 317 .. 278 317 .. 0.81 4 ! 13.1 0.1 0.0085 0.69 12 38 .] 332 359 .. 322 359 .. 0.81 5 ! 13.7 0.0 0.0056 0.45 2 38 .] 365 401 .. 364 401 .. 0.79 6 ! 14.9 0.0 0.0022 0.18 3 37 .. 407 442 .. 405 442 .. 0.86 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 4.9 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 G s v+s+ f++d +++a ++ ++++++ sp|Q8NHY2-3|RFWD2_HUMAN 195 GS-SiVSSIEFDRDCDYFAIAGVTKKIKVY 223 44.348***********9977779999887 PP == domain 2 score: 14.5 bits; conditional E-value: 0.0031 SSSEEEEEEETTSSEEEEEET.TSEEEEEE CS WD40 10 HssvtslafspdgawlasGsd.DgtvriWd 38 s ++++++s++++ l+++sd gtv +Wd sp|Q8NHY2-3|RFWD2_HUMAN 245 NSKISCISWSSYHKNLLASSDyEGTVILWD 274 4449****99999998777644*******9 PP == domain 3 score: 15.4 bits; conditional E-value: 0.0016 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 q +++ H + +s++ + d ++lasGsdD +v++W+ sp|Q8NHY2-3|RFWD2_HUMAN 279 QRSKVYQEHeKRCWSVDfNLMDPKLLASGSDDAKVKLWS 317 566889999988999976556666699***********5 PP == domain 4 score: 13.1 bits; conditional E-value: 0.0085 SEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 12 svtslafspdgawlas.GsdDgtvriWd 38 +v++++fsp+++++++ G+ D+ v+ +d sp|Q8NHY2-3|RFWD2_HUMAN 332 NVCCVKFSPSSRYHLAfGCADHCVHYYD 359 49***********7655778***99876 PP == domain 5 score: 13.7 bits; conditional E-value: 0.0056 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q++ +++GH + v s a +g ++s+s D +++W+ sp|Q8NHY2-3|RFWD2_HUMAN 365 QPIMVFKGHrKAV-SYAKFVSGEEIVSASTDSQLKLWN 401 7999*****999*.6655555555677888*******8 PP == domain 6 score: 14.9 bits; conditional E-value: 0.0022 EEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ss...vtslafspdgawlasGsdDgtvriW 37 clr+++GH + v +l ++g+++a+Gs++++++++ sp|Q8NHY2-3|RFWD2_HUMAN 407 CLRSFKGHiNEknfV-GL--ASNGDYIACGSENNSLYLY 442 9*******9555557.88..99***********999876 PP >> sp|Q9NV06|DCA13_HUMAN DDB1- and CUL4-associated factor 13 OS=Homo sapiens GN=DCAF13 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.0 2.1e-05 0.0017 4 38 .] 59 95 .. 57 95 .. 0.82 2 ! 18.8 0.1 0.00013 0.011 2 38 .] 100 137 .. 99 137 .. 0.91 3 ? 9.9 0.1 0.086 7 10 38 .] 196 225 .. 186 225 .. 0.80 4 ! 14.6 0.0 0.0027 0.22 9 37 .. 280 309 .. 273 309 .. 0.88 5 ! 17.9 0.0 0.00026 0.021 10 38 .] 327 353 .. 317 353 .. 0.86 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 2.1e-05 EEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 l +l+GH ++v++la +p++ ++sG Dg vriW+ sp|Q9NV06|DCA13_HUMAN 59 LASLDGHrDGVNCLAKHPEKLAtVLSGACDGEVRIWN 95 6789***999****966665556889966*******8 PP == domain 2 score: 18.8 bits; conditional E-value: 0.00013 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+rt+ +H ++v+++++ g+ +++ +dD+tv+ W+ sp|Q9NV06|DCA13_HUMAN 100 NCIRTIQAHeGFVRGICTRFCGTSFFTVGDDKTVKQWK 137 8********888*****9999999998888*******6 PP == domain 3 score: 9.9 bits; conditional E-value: 0.086 SSSEEEEEEETTSSEEE.EE.ETTSEEEEEE CS WD40 10 Hssvtslafspdgawla.sG.sdDgtvriWd 38 +s++s++f+p ++l+ s+ s D+++ ++d sp|Q9NV06|DCA13_HUMAN 196 FDSISSVKFNPIETFLLgSCaS-DRNIVLYD 225 4569************965535.*****998 PP == domain 4 score: 14.6 bits; conditional E-value: 0.0027 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 H s v ++++sp g+ ++s+s D+++ri+ sp|Q9NV06|DCA13_HUMAN 280 DHvSAVLDVDYSPTGKEFVSASFDKSIRIF 309 4877799**************99*****96 PP == domain 5 score: 17.9 bits; conditional E-value: 0.00026 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 H v ++++ +d++++++Gsd ++r+W+ sp|Q9NV06|DCA13_HUMAN 327 H--VICVKWTSDSKYIMCGSDEMNIRLWK 353 4..88***********************6 PP >> tr|G3V3G9|G3V3G9_HUMAN DDB1- and CUL4-associated factor 8 OS=Homo sapiens GN=DCAF8 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.5 1.1e-07 9.2e-06 2 38 .] 338 375 .. 337 375 .. 0.93 2 ? 5.1 0.0 2.9 2.3e+02 5 36 .. 383 418 .. 379 418 .. 0.73 3 ? 3.9 0.0 6.5 5.3e+02 16 38 .] 500 514 .. 487 514 .. 0.81 4 ? 7.7 0.0 0.42 34 10 38 .] 534 569 .. 526 569 .. 0.75 5 ! 14.8 0.0 0.0024 0.2 2 37 .. 577 616 .. 576 617 .. 0.89 6 ! 14.6 0.0 0.0027 0.22 8 37 .. 628 659 .. 621 659 .. 0.82 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 1.1e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ l+GH ++v+ l f++ g+wlasGsdD +v +Wd tr|G3V3G9|G3V3G9_HUMAN 338 RLQHGLEGHtGCVNTLHFNQRGTWLASGSDDLKVVVWD 375 57899****777*************************9 PP == domain 2 score: 5.1 bits; conditional E-value: 2.9 EEE.ESS.SSEEEEE...EETTSSEEEEEETTSEEEE CS WD40 5 rtl.tGH.ssvtsla...fspdgawlasGsdDgtvri 36 + +GH s+v + +s d+++ + + +Dg vr+ tr|G3V3G9|G3V3G9_HUMAN 383 LDFeSGHkSNVFQAKflpNSGDSTLAM-CARDGQVRV 418 555259*66697666888999999988.566****97 PP == domain 3 score: 3.9 bits; conditional E-value: 6.5 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 + +a G++D+ vri+d tr|G3V3G9|G3V3G9_HUMAN 500 Q--------FAVGGRDQFVRIYD 514 2........678**********8 PP == domain 4 score: 7.7 bits; conditional E-value: 0.42 S..SS.....EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H..ss.....vtslafspdgawlasGsdDgtvriWd 38 H +s +t+l +s+dg+ l+++ D +++++ tr|G3V3G9|G3V3G9_HUMAN 534 HlvNSeskanITCLVYSHDGTELLASYNDEDIYLFN 569 3433344567*************9998898888876 PP == domain 5 score: 14.8 bits; conditional E-value: 0.0024 EEEEEEESS.SS..EEEEE.EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ss..vtsla.fspdgawlasGsdDgtvriW 37 q ++ ++GH ++ v ++ + p + +++sGsd g++ +W tr|G3V3G9|G3V3G9_HUMAN 577 QYVKRYKGHrNNatVKGVNfYGPKSEFVVSGSDCGHIFLW 616 56788****966799***999999999************* PP == domain 6 score: 14.6 bits; conditional E-value: 0.0027 ESSSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHss..vtslafspdgawlasGsdDgtvriW 37 +G ++ v++l +p+ + la+++ D+ v+iW tr|G3V3G9|G3V3G9_HUMAN 628 EGDKGgvVNCLEPHPHLPVLATSGLDHDVKIW 659 55533467*************9999******* PP >> tr|H0Y339|H0Y339_HUMAN E3 ubiquitin-protein ligase RFWD2 (Fragment) OS=Homo sapiens GN=RFWD2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 5.6 4.6e+02 9 37 .. 255 283 .. 242 284 .. 0.81 2 ! 14.3 0.1 0.0035 0.29 10 38 .] 305 334 .. 296 334 .. 0.80 3 ! 15.2 0.0 0.0019 0.15 2 38 .] 339 377 .. 338 377 .. 0.81 4 ! 12.9 0.1 0.0097 0.79 12 38 .] 392 419 .. 382 419 .. 0.81 5 ! 13.5 0.0 0.0064 0.52 2 38 .] 425 461 .. 424 461 .. 0.79 6 ! 14.7 0.0 0.0026 0.21 3 37 .. 467 502 .. 465 502 .. 0.86 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 5.6 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 G s v+s+ f++d +++a ++ ++++++ tr|H0Y339|H0Y339_HUMAN 255 GS-SiVSSIEFDRDCDYFAIAGVTKKIKVY 283 44.348***********9977779999887 PP == domain 2 score: 14.3 bits; conditional E-value: 0.0035 SSSEEEEEEETTSSEEEEEET.TSEEEEEE CS WD40 10 HssvtslafspdgawlasGsd.DgtvriWd 38 s ++++++s++++ l+++sd gtv +Wd tr|H0Y339|H0Y339_HUMAN 305 NSKISCISWSSYHKNLLASSDyEGTVILWD 334 4449****99999998777644*******9 PP == domain 3 score: 15.2 bits; conditional E-value: 0.0019 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 q +++ H + +s++ + d ++lasGsdD +v++W+ tr|H0Y339|H0Y339_HUMAN 339 QRSKVYQEHeKRCWSVDfNLMDPKLLASGSDDAKVKLWS 377 566889999988999976556666699***********5 PP == domain 4 score: 12.9 bits; conditional E-value: 0.0097 SEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 12 svtslafspdgawlas.GsdDgtvriWd 38 +v++++fsp+++++++ G+ D+ v+ +d tr|H0Y339|H0Y339_HUMAN 392 NVCCVKFSPSSRYHLAfGCADHCVHYYD 419 49***********7655778***99876 PP == domain 5 score: 13.5 bits; conditional E-value: 0.0064 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q++ +++GH + v s a +g ++s+s D +++W+ tr|H0Y339|H0Y339_HUMAN 425 QPIMVFKGHrKAV-SYAKFVSGEEIVSASTDSQLKLWN 461 7999*****999*.6655555555677888*******8 PP == domain 6 score: 14.7 bits; conditional E-value: 0.0026 EEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ss...vtslafspdgawlasGsdDgtvriW 37 clr+++GH + v +l ++g+++a+Gs++++++++ tr|H0Y339|H0Y339_HUMAN 467 CLRSFKGHiNEknfV-GL--ASNGDYIACGSENNSLYLY 502 9*******9555557.88..99***********999876 PP >> tr|M0QZM0|M0QZM0_HUMAN Striatin-4 (Fragment) OS=Homo sapiens GN=STRN4 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.8 0.1 1.9e-07 1.5e-05 1 38 [] 109 147 .. 109 147 .. 0.94 2 ! 13.0 0.0 0.0088 0.71 2 38 .] 163 200 .. 162 200 .. 0.94 3 ! 41.1 0.4 1.2e-11 9.5e-10 4 38 .] 218 253 .. 215 253 .. 0.92 Alignments for each domain: == domain 1 score: 27.8 bits; conditional E-value: 1.9e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ tl+ H ++++slaf+++++ l+++s+Dgt+++W+ tr|M0QZM0|M0QZM0_HUMAN 109 WNPKFTLRSHyDGIRSLAFHHSQSALLTASEDGTLKLWN 147 578899****999*************************8 PP == domain 2 score: 13.0 bits; conditional E-value: 0.0088 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ +++H ++v ++a +++ + sG+ D ++ W+ tr|M0QZM0|M0QZM0_HUMAN 163 EPIHAFRAHrGPVLAVAMGSNSEYCYSGGADACIHSWK 200 5899*****999***********************995 PP == domain 3 score: 41.1 bits; conditional E-value: 1.2e-11 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+GH + v++lafsp ++ las+s DgtvriWd tr|M0QZM0|M0QZM0_HUMAN 218 SHVLEGHgDAVWGLAFSPTSQRLASCSADGTVRIWD 253 699****666*************************9 PP >> tr|H0Y4R9|H0Y4R9_HUMAN Bromodomain and WD repeat-containing protein 1 (Fragment) OS=Homo sapiens GN=BRWD1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.1 2.4 2e+02 25 37 .. 2 13 .. 1 14 [. 0.83 2 ? 9.8 0.0 0.093 7.5 17 37 .. 43 63 .. 29 63 .. 0.87 3 ! 24.1 0.0 2.8e-06 0.00023 4 37 .. 73 107 .. 70 108 .. 0.89 4 ? 10.5 0.0 0.055 4.5 13 38 .] 141 166 .. 128 166 .. 0.90 5 ! 18.0 0.1 0.00023 0.019 1 38 [] 170 209 .. 170 209 .. 0.75 6 ? 11.8 0.2 0.022 1.8 7 32 .. 225 248 .. 214 255 .. 0.77 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 2.4 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 +++G Dgtv +W tr|H0Y4R9|H0Y4R9_HUMAN 2 VSTGA-DGTVCFW 13 46788.******* PP == domain 2 score: 9.8 bits; conditional E-value: 0.093 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 +fs g +la+Gs D+ +r++ tr|H0Y4R9|H0Y4R9_HUMAN 43 SFSVGGMFLATGSTDHVIRMY 63 5999999************86 PP == domain 3 score: 24.1 bits; conditional E-value: 2.8e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+ H + v s++f+ +g+ ++sGs+Dgt riW tr|H0Y4R9|H0Y4R9_HUMAN 73 IAELESHtDKVDSIQFCNNGDRFLSGSRDGTARIW 107 678999*555************************* PP == domain 4 score: 10.5 bits; conditional E-value: 0.055 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 vt +a++++ + ++++ D+ +++W+ tr|H0Y4R9|H0Y4R9_HUMAN 141 VTMIAWNQNDSIVVTAVNDHVLKVWN 166 77799**********988*******8 PP == domain 5 score: 18.0 bits; conditional E-value: 0.00023 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 gq+l+ l GH + v l ++p + l++G+ Dg++ iWd tr|H0Y4R9|H0Y4R9_HUMAN 170 GQLLHNLMGHaDEVFVLETHPFDSRimLSAGH-DGSIFIWD 209 68999*****6669888866666663234566.*******9 PP == domain 6 score: 11.8 bits; conditional E-value: 0.022 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fs+dg+ +a ++ D tr|H0Y4R9|H0Y4R9_HUMAN 225 GQGHGAVFDCKFSQDGQHFA-CT-DS 248 469988************97.65.43 PP >> tr|M0R317|M0R317_HUMAN Striatin-4 (Fragment) OS=Homo sapiens GN=STRN4 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.1 0.00059 0.048 25 38 .] 4 17 .. 1 17 [. 0.91 2 ? 7.1 0.0 0.66 53 12 36 .. 81 108 .. 68 110 .. 0.79 3 ! 39.6 0.1 3.5e-11 2.8e-09 1 38 [] 114 152 .. 114 152 .. 0.96 4 ! 14.9 0.0 0.0022 0.18 2 32 .. 157 192 .. 156 197 .. 0.85 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 0.00059 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 las+s DgtvriWd tr|M0R317|M0R317_HUMAN 4 LASCSADGTVRIWD 17 799**********9 PP == domain 2 score: 7.1 bits; conditional E-value: 0.66 S...EEEEEEETTSSEEEEEETTSEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvri 36 + ++ + +p++++ ++++dD+ +r+ tr|M0R317|M0R317_HUMAN 81 GptqINQVVSHPNQPLTITAHDDRGIRF 108 2356999*********889*****9996 PP == domain 3 score: 39.6 bits; conditional E-value: 3.5e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+++++ +H + vt+la++p+ga+l+sGs D+++r+W+ tr|M0R317|M0R317_HUMAN 114 GKPVHSMVAHlDAVTCLAVDPNGAFLMSGSHDCSLRLWS 152 689*******999****************99*******5 PP == domain 4 score: 14.9 bits; conditional E-value: 0.0022 EEEEEEESS..SS...EEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGH..ss...vtslafspdgawlasGsdDg 32 +c++++t+H ++ ++++a +p++a++as++ D tr|M0R317|M0R317_HUMAN 157 TCVQEITAHrkKHeeaIHAVACHPSKALIASAGADA 192 699999***9655999**************998886 PP >> sp|Q8TEB1-2|DCA11_HUMAN Isoform 2 of DDB1- and CUL4-associated factor 11 OS=Homo sapiens GN=DCAF11 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.063 5.1 18 38 .] 154 174 .. 129 174 .. 0.87 2 ? 3.4 0.1 9.6 7.8e+02 12 31 .. 194 213 .. 182 220 .. 0.75 3 ? 5.8 0.0 1.7 1.4e+02 13 38 .] 242 267 .. 225 267 .. 0.88 4 ! 17.0 0.0 0.0005 0.041 4 38 .] 272 310 .. 269 310 .. 0.75 5 ! 20.4 0.0 4e-05 0.0033 2 38 .] 320 357 .. 319 357 .. 0.92 6 ? 4.8 0.1 3.4 2.8e+02 4 38 .] 402 443 .. 400 443 .. 0.69 7 ! 24.0 0.5 2.9e-06 0.00024 3 37 .. 449 484 .. 447 485 .. 0.90 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.063 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 +s+dg+ ++s++ D+t+r++d sp|Q8TEB1-2|DCA11_HUMAN 154 YSKDGQIFMSACQDQTIRLYD 174 89*****************98 PP == domain 2 score: 3.4 bits; conditional E-value: 9.6 SEEEEEEETTSSEEE.EEETT CS WD40 12 svtslafspdgawla.sGsdD 31 sv ++af pdg+ ++ s s+ sp|Q8TEB1-2|DCA11_HUMAN 194 SVLDVAFTPDGNHFLyS-SWS 213 3889*********7535.443 PP == domain 3 score: 5.8 bits; conditional E-value: 1.7 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v s+a+s+dg+ ++ G Dg ++++d sp|Q8TEB1-2|DCA11_HUMAN 242 VFSIAVSSDGREVLGGANDGCLYVFD 267 8899**********7778*****998 PP == domain 4 score: 17.0 bits; conditional E-value: 0.0005 EEEEE..SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 4 lrtlt..GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 rtl H ++v+++af + ++ l+sG+dD +++Wd sp|Q8TEB1-2|DCA11_HUMAN 272 RRTLQieSHeDDVNAVAFADISSQiLFSGGDDAICKVWD 310 55653339*888****96666666356***********9 PP == domain 5 score: 20.4 bits; conditional E-value: 4e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ l GH +++t ++ d ++l+s s+D+t+++Wd sp|Q8TEB1-2|DCA11_HUMAN 320 KPVGALAGHqDGITFIDSKGDARYLISNSKDQTIKLWD 357 5788899**777**************88*********9 PP == domain 6 score: 4.8 bits; conditional E-value: 3.4 EEEEESSSSE.EEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHssv.tsla.......fspdgawlasGsdDgtvriWd 38 l t++GH +v + l s ++++ sG+ g+v ++d sp|Q8TEB1-2|DCA11_HUMAN 402 LMTYRGH-GVlHTLIrcrfspiHSTGQQFIYSGCSTGKVVVYD 443 789****.75444445555576666667788997699988887 PP == domain 7 score: 24.0 bits; conditional E-value: 2.9e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++lt H +v++++++p ++s+s+Dg++r+W sp|Q8TEB1-2|DCA11_HUMAN 449 IVKKLTNHkACVRDVSWHPFEEKIVSSSWDGNLRLW 484 578899**666************************* PP >> sp|Q8TEB1|DCA11_HUMAN DDB1- and CUL4-associated factor 11 OS=Homo sapiens GN=DCAF11 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.067 5.4 18 38 .] 180 200 .. 155 200 .. 0.87 2 ? 5.7 0.0 1.9 1.5e+02 13 38 .] 268 293 .. 251 293 .. 0.88 3 ! 16.9 0.0 0.00054 0.043 4 38 .] 298 336 .. 295 336 .. 0.75 4 ! 20.4 0.0 4.3e-05 0.0035 2 38 .] 346 383 .. 345 383 .. 0.92 5 ? 4.8 0.1 3.6 2.9e+02 4 38 .] 428 469 .. 426 469 .. 0.69 6 ! 24.0 0.5 3.1e-06 0.00025 3 37 .. 475 510 .. 473 511 .. 0.90 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.067 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 +s+dg+ ++s++ D+t+r++d sp|Q8TEB1|DCA11_HUMAN 180 YSKDGQIFMSACQDQTIRLYD 200 89*****************98 PP == domain 2 score: 5.7 bits; conditional E-value: 1.9 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v s+a+s+dg+ ++ G Dg ++++d sp|Q8TEB1|DCA11_HUMAN 268 VFSIAVSSDGREVLGGANDGCLYVFD 293 8899**********7778*****998 PP == domain 3 score: 16.9 bits; conditional E-value: 0.00054 EEEEE..SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 4 lrtlt..GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 rtl H ++v+++af + ++ l+sG+dD +++Wd sp|Q8TEB1|DCA11_HUMAN 298 RRTLQieSHeDDVNAVAFADISSQiLFSGGDDAICKVWD 336 55653339*888****96666666356***********9 PP == domain 4 score: 20.4 bits; conditional E-value: 4.3e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ l GH +++t ++ d ++l+s s+D+t+++Wd sp|Q8TEB1|DCA11_HUMAN 346 KPVGALAGHqDGITFIDSKGDARYLISNSKDQTIKLWD 383 5788899**777**************88*********9 PP == domain 5 score: 4.8 bits; conditional E-value: 3.6 EEEEESSSSE.EEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHssv.tsla.......fspdgawlasGsdDgtvriWd 38 l t++GH +v + l s ++++ sG+ g+v ++d sp|Q8TEB1|DCA11_HUMAN 428 LMTYRGH-GVlHTLIrcrfspiHSTGQQFIYSGCSTGKVVVYD 469 789****.75444445555576666667788997699988887 PP == domain 6 score: 24.0 bits; conditional E-value: 3.1e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++lt H +v++++++p ++s+s+Dg++r+W sp|Q8TEB1|DCA11_HUMAN 475 IVKKLTNHkACVRDVSWHPFEEKIVSSSWDGNLRLW 510 578899**666************************* PP >> sp|Q8N5D0-4|WDTC1_HUMAN Isoform 4 of WD and tetratricopeptide repeats protein 1 OS=Homo sapiens GN=WDTC1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 0.1 1.3e-07 1e-05 6 38 .] 42 75 .. 39 75 .. 0.92 2 ? 7.1 0.1 0.66 54 4 38 .] 83 120 .. 80 120 .. 0.74 3 ! 16.6 0.1 0.00068 0.055 6 37 .. 528 564 .. 523 565 .. 0.87 4 ! 22.2 0.0 1.1e-05 0.00092 2 38 .] 570 607 .. 569 607 .. 0.91 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 1.3e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH ++v++l ++ g++lasGsdD++ +Wd sp|Q8N5D0-4|WDTC1_HUMAN 42 ELQGHsGCVNCLEWNEKGDLLASGSDDQHTIVWD 75 689**666*************************9 PP == domain 2 score: 7.1 bits; conditional E-value: 0.66 EEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 l tGH ++ s++ + + l++G D +v++ d sp|Q8N5D0-4|WDTC1_HUMAN 83 LSMHTGHtANIFSVKflPHAGDRILITGAADSKVHVHD 120 45567**777****8765556666889*99***99865 PP == domain 3 score: 16.6 bits; conditional E-value: 0.00068 EEESS.SSEEEEE....EETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtsla....fspdgawlasGsdDgtvriW 37 + GH + t+++ f ++ ++++sGsdDg+ iW sp|Q8N5D0-4|WDTC1_HUMAN 528 RYCGHcNTTTDIKeanfFGSNAQYIVSGSDDGSFFIW 564 57799777899999999******************** PP == domain 4 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++r+l G s v++l+ +p+ +la+++ D+ vr+W+ sp|Q8N5D0-4|WDTC1_HUMAN 570 NLVRVLQGDeSIVNCLQPHPSYCFLATSGIDPVVRLWN 607 5789999995558************************8 PP >> sp|Q8N5D0|WDTC1_HUMAN WD and tetratricopeptide repeats protein 1 OS=Homo sapiens GN=WDTC1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 0.1 1.3e-07 1e-05 6 38 .] 42 75 .. 39 75 .. 0.92 2 ? 7.1 0.1 0.67 54 4 38 .] 83 120 .. 80 120 .. 0.74 3 ! 16.6 0.1 0.00068 0.055 6 37 .. 529 565 .. 524 566 .. 0.87 4 ! 22.2 0.0 1.1e-05 0.00093 2 38 .] 571 608 .. 570 608 .. 0.91 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 1.3e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH ++v++l ++ g++lasGsdD++ +Wd sp|Q8N5D0|WDTC1_HUMAN 42 ELQGHsGCVNCLEWNEKGDLLASGSDDQHTIVWD 75 689**666*************************9 PP == domain 2 score: 7.1 bits; conditional E-value: 0.67 EEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 l tGH ++ s++ + + l++G D +v++ d sp|Q8N5D0|WDTC1_HUMAN 83 LSMHTGHtANIFSVKflPHAGDRILITGAADSKVHVHD 120 45567**777****8765556666889*99***99865 PP == domain 3 score: 16.6 bits; conditional E-value: 0.00068 EEESS.SSEEEEE....EETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtsla....fspdgawlasGsdDgtvriW 37 + GH + t+++ f ++ ++++sGsdDg+ iW sp|Q8N5D0|WDTC1_HUMAN 529 RYCGHcNTTTDIKeanfFGSNAQYIVSGSDDGSFFIW 565 57799777899999999******************** PP == domain 4 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++r+l G s v++l+ +p+ +la+++ D+ vr+W+ sp|Q8N5D0|WDTC1_HUMAN 571 NLVRVLQGDeSIVNCLQPHPSYCFLATSGIDPVVRLWN 608 5789999995558************************8 PP >> sp|Q5JSH3-2|WDR44_HUMAN Isoform 2 of WD repeat-containing protein 44 OS=Homo sapiens GN=WDR44 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.1 0.00011 0.009 9 37 .. 509 538 .. 500 538 .. 0.87 2 ! 21.9 0.1 1.4e-05 0.0011 3 37 .. 599 633 .. 597 634 .. 0.85 3 ! 20.0 0.1 5.6e-05 0.0046 2 38 .] 639 676 .. 638 676 .. 0.83 4 ? 6.1 0.0 1.3 1.1e+02 9 38 .] 690 720 .. 683 720 .. 0.84 5 ? 5.7 0.0 1.8 1.5e+02 26 38 .] 794 806 .. 775 806 .. 0.75 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 0.00011 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 H + v+ ++fs+ g++las++ D+ vriW sp|Q5JSH3-2|WDR44_HUMAN 509 EHmGAVWTMKFSHCGRLLASAGQDNVVRIW 538 47888************************* PP == domain 2 score: 21.9 bits; conditional E-value: 1.4e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +++GH + +l++s++ +l+ +s+D+tvr+W sp|Q5JSH3-2|WDR44_HUMAN 599 PFCKYKGHtADLLDLSWSKNYFLLS-SSMDKTVRLW 633 56689***88899*******99985.666******* PP == domain 3 score: 20.0 bits; conditional E-value: 5.6e-05 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +cl + H ++vt++af+p + ++sGs Dg++r+W+ sp|Q5JSH3-2|WDR44_HUMAN 639 ECLCCF-QHiDFVTAIAFHPRDDRyFLSGSLDGKLRLWN 676 677777.59999*****7666666688***********8 PP == domain 4 score: 6.1 bits; conditional E-value: 1.3 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 G+ + +t+ f+++g++ + G++Dg + ++d sp|Q5JSH3-2|WDR44_HUMAN 690 GQtKLITAANFCQNGKYAVIGTYDGRCIFYD 720 6634499999*******999*99***99987 PP == domain 5 score: 5.7 bits; conditional E-value: 1.8 EEEETTSEEEEEE CS WD40 26 asGsdDgtvriWd 38 +sGs+D+ v+iW+ sp|Q5JSH3-2|WDR44_HUMAN 794 FSGSEDKYVYIWS 806 38**********5 PP >> sp|Q13216|ERCC8_HUMAN DNA excision repair protein ERCC-8 OS=Homo sapiens GN=ERCC8 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.74 60 10 38 .] 42 72 .. 39 72 .. 0.77 2 ? 12.8 0.4 0.01 0.82 9 38 .] 97 128 .. 85 128 .. 0.71 3 ! 30.4 0.1 2.9e-08 2.4e-06 1 38 [] 176 215 .. 176 215 .. 0.92 4 ! 17.6 0.1 0.00033 0.026 8 38 .] 242 273 .. 222 273 .. 0.87 5 ! 14.4 0.0 0.0033 0.27 2 37 .. 325 361 .. 324 362 .. 0.87 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.74 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H ++++ l+ + +g++++sG+ Dg + ++d sp|Q13216|ERCC8_HUMAN 42 HgGGINTLDiEPVEGRYMLSGGSDGVIVLYD 72 54456666666668999999988*****998 PP == domain 2 score: 12.8 bits; conditional E-value: 0.01 SS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawla.sGsdDgtvriWd 38 H sv +++ p+ + ++ s+s D+t+++Wd sp|Q13216|ERCC8_HUMAN 97 VHrYSVETVQWYPHDTGMFtSSSFDKTLKVWD 128 454458888766666665516678*******9 PP == domain 3 score: 30.4 bits; conditional E-value: 2.9e-08 TEEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 g+c ++l GH + + ++++sp +++ a++s D v++Wd sp|Q13216|ERCC8_HUMAN 176 GSCSHILQGHrQEILAVSWSPRYDYIlATASADSRVKLWD 215 68********999************6268899*******9 PP == domain 4 score: 17.6 bits; conditional E-value: 0.00033 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 t+H++ v++l+f +dg l++ + D+ r+W+ sp|Q13216|ERCC8_HUMAN 242 TAHNGkVNGLCFTSDGLHLLTVGTDNRMRLWN 273 689556************997666*******8 PP == domain 5 score: 14.4 bits; conditional E-value: 0.0033 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++ l+GH + v ++ f+++ + l sGs+D+++ W sp|Q13216|ERCC8_HUMAN 325 EQITMLKGHyKTVDCCVFQSNFQELYSGSRDCNILAW 361 667889*******77779999999*********9877 PP >> sp|Q8NHY2-4|RFWD2_HUMAN Isoform 4 of E3 ubiquitin-protein ligase RFWD2 OS=Homo sapiens GN=RFWD2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7.4 6e+02 9 37 .. 400 428 .. 387 429 .. 0.81 2 ! 13.9 0.1 0.0047 0.38 10 38 .] 450 479 .. 441 479 .. 0.80 3 ! 14.8 0.0 0.0025 0.2 2 38 .] 484 522 .. 483 522 .. 0.81 4 ? 12.5 0.1 0.013 1 12 38 .] 537 564 .. 527 564 .. 0.81 5 ! 13.1 0.0 0.0085 0.69 2 38 .] 570 606 .. 569 606 .. 0.79 6 ! 14.3 0.0 0.0034 0.28 3 37 .. 612 647 .. 610 647 .. 0.86 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.4 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 G s v+s+ f++d +++a ++ ++++++ sp|Q8NHY2-4|RFWD2_HUMAN 400 GS-SiVSSIEFDRDCDYFAIAGVTKKIKVY 428 44.348***********9977779999887 PP == domain 2 score: 13.9 bits; conditional E-value: 0.0047 SSSEEEEEEETTSSEEEEEET.TSEEEEEE CS WD40 10 HssvtslafspdgawlasGsd.DgtvriWd 38 s ++++++s++++ l+++sd gtv +Wd sp|Q8NHY2-4|RFWD2_HUMAN 450 NSKISCISWSSYHKNLLASSDyEGTVILWD 479 4449****99999998777644*******9 PP == domain 3 score: 14.8 bits; conditional E-value: 0.0025 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 q +++ H + +s++ + d ++lasGsdD +v++W+ sp|Q8NHY2-4|RFWD2_HUMAN 484 QRSKVYQEHeKRCWSVDfNLMDPKLLASGSDDAKVKLWS 522 566889999988999976556666699***********5 PP == domain 4 score: 12.5 bits; conditional E-value: 0.013 SEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 12 svtslafspdgawlas.GsdDgtvriWd 38 +v++++fsp+++++++ G+ D+ v+ +d sp|Q8NHY2-4|RFWD2_HUMAN 537 NVCCVKFSPSSRYHLAfGCADHCVHYYD 564 49***********7655778***99876 PP == domain 5 score: 13.1 bits; conditional E-value: 0.0085 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q++ +++GH + v s a +g ++s+s D +++W+ sp|Q8NHY2-4|RFWD2_HUMAN 570 QPIMVFKGHrKAV-SYAKFVSGEEIVSASTDSQLKLWN 606 7999*****999*.6655555555677888*******8 PP == domain 6 score: 14.3 bits; conditional E-value: 0.0034 EEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ss...vtslafspdgawlasGsdDgtvriW 37 clr+++GH + v +l ++g+++a+Gs++++++++ sp|Q8NHY2-4|RFWD2_HUMAN 612 CLRSFKGHiNEknfV-GL--ASNGDYIACGSENNSLYLY 647 9*******9555557.88..99***********999875 PP >> sp|Q8NHY2-2|RFWD2_HUMAN Isoform 2 of E3 ubiquitin-protein ligase RFWD2 OS=Homo sapiens GN=RFWD2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7.4 6e+02 9 37 .. 396 424 .. 383 425 .. 0.81 2 ! 13.9 0.1 0.0047 0.38 10 38 .] 446 475 .. 437 475 .. 0.80 3 ! 14.8 0.0 0.0025 0.2 2 38 .] 480 518 .. 479 518 .. 0.81 4 ? 12.5 0.1 0.013 1 12 38 .] 533 560 .. 523 560 .. 0.81 5 ! 13.1 0.0 0.0084 0.68 2 38 .] 566 602 .. 565 602 .. 0.79 6 ! 14.3 0.0 0.0034 0.27 3 37 .. 608 643 .. 606 643 .. 0.86 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.4 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 G s v+s+ f++d +++a ++ ++++++ sp|Q8NHY2-2|RFWD2_HUMAN 396 GS-SiVSSIEFDRDCDYFAIAGVTKKIKVY 424 44.348***********9977779999887 PP == domain 2 score: 13.9 bits; conditional E-value: 0.0047 SSSEEEEEEETTSSEEEEEET.TSEEEEEE CS WD40 10 HssvtslafspdgawlasGsd.DgtvriWd 38 s ++++++s++++ l+++sd gtv +Wd sp|Q8NHY2-2|RFWD2_HUMAN 446 NSKISCISWSSYHKNLLASSDyEGTVILWD 475 4449****99999998777644*******9 PP == domain 3 score: 14.8 bits; conditional E-value: 0.0025 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 q +++ H + +s++ + d ++lasGsdD +v++W+ sp|Q8NHY2-2|RFWD2_HUMAN 480 QRSKVYQEHeKRCWSVDfNLMDPKLLASGSDDAKVKLWS 518 566889999988999976556666699***********5 PP == domain 4 score: 12.5 bits; conditional E-value: 0.013 SEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 12 svtslafspdgawlas.GsdDgtvriWd 38 +v++++fsp+++++++ G+ D+ v+ +d sp|Q8NHY2-2|RFWD2_HUMAN 533 NVCCVKFSPSSRYHLAfGCADHCVHYYD 560 49***********7655778***99876 PP == domain 5 score: 13.1 bits; conditional E-value: 0.0084 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q++ +++GH + v s a +g ++s+s D +++W+ sp|Q8NHY2-2|RFWD2_HUMAN 566 QPIMVFKGHrKAV-SYAKFVSGEEIVSASTDSQLKLWN 602 7999*****999*.6655555555677888*******8 PP == domain 6 score: 14.3 bits; conditional E-value: 0.0034 EEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ss...vtslafspdgawlasGsdDgtvriW 37 clr+++GH + v +l ++g+++a+Gs++++++++ sp|Q8NHY2-2|RFWD2_HUMAN 608 CLRSFKGHiNEknfV-GL--ASNGDYIACGSENNSLYLY 643 9*******9555557.88..99***********999875 PP >> sp|O43684-2|BUB3_HUMAN Isoform 2 of Mitotic checkpoint protein BUB3 OS=Homo sapiens GN=BUB3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 0.0025 0.2 12 38 .] 16 43 .. 4 43 .. 0.85 2 ? 7.1 0.1 0.68 55 10 37 .. 55 82 .. 48 83 .. 0.82 3 ! 24.7 0.0 1.9e-06 0.00015 9 38 .] 94 124 .. 88 124 .. 0.91 4 ! 16.3 0.0 0.00083 0.067 8 38 .] 222 262 .. 215 262 .. 0.78 5 ? 7.0 0.0 0.69 56 10 29 .. 273 295 .. 265 305 .. 0.71 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 0.0025 SEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriWd 38 +++s++fsp+ + l+ +s+D +vr++d sp|O43684-2|BUB3_HUMAN 16 GISSVKFSPNTSQfLLVSSWDTSVRLYD 43 499**********54589********98 PP == domain 2 score: 7.1 bits; conditional E-value: 0.68 S.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriW 37 H + v ++a ++p +aw sG+ D+ +++ sp|O43684-2|BUB3_HUMAN 55 HtGAVLDCAfYDPTHAW--SGGLDHQLKMH 82 7555988888*******..8**9***9985 PP == domain 3 score: 24.7 bits; conditional E-value: 1.9e-06 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++++ ++p+ + +++Gs+D+tv++Wd sp|O43684-2|BUB3_HUMAN 94 THdAPIRCVEYCPEVNVMVTGSWDQTVKLWD 124 68777*************************9 PP == domain 4 score: 16.3 bits; conditional E-value: 0.00083 ESS..SS........EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ss........vtslafspdgawlasGsdDgtvriWd 38 + H + v++++f+ ++ +a+G+ Dg v iWd sp|O43684-2|BUB3_HUMAN 222 KCHrlKEnnieqiypVNAISFHNIHNTFATGGSDGFVNIWD 262 5555433445666669***************88*******9 PP == domain 5 score: 7.0 bits; conditional E-value: 0.69 S...SSEEEEEEETTSSEEEEEE CS WD40 10 H...ssvtslafspdgawlasGs 29 H +s+ slafs dg+ la +s sp|O43684-2|BUB3_HUMAN 273 HrypTSIASLAFSNDGTTLAIAS 295 55445699**********98443 PP >> sp|O43684|BUB3_HUMAN Mitotic checkpoint protein BUB3 OS=Homo sapiens GN=BUB3 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 0.0025 0.2 12 38 .] 16 43 .. 4 43 .. 0.85 2 ? 7.0 0.1 0.69 56 10 37 .. 55 82 .. 48 83 .. 0.82 3 ! 24.7 0.0 1.9e-06 0.00015 9 38 .] 94 124 .. 88 124 .. 0.91 4 ! 16.3 0.0 0.00084 0.068 8 38 .] 222 262 .. 215 262 .. 0.78 5 ? 7.0 0.0 0.7 57 10 29 .. 273 295 .. 265 305 .. 0.71 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 0.0025 SEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriWd 38 +++s++fsp+ + l+ +s+D +vr++d sp|O43684|BUB3_HUMAN 16 GISSVKFSPNTSQfLLVSSWDTSVRLYD 43 499**********54589********98 PP == domain 2 score: 7.0 bits; conditional E-value: 0.69 S.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriW 37 H + v ++a ++p +aw sG+ D+ +++ sp|O43684|BUB3_HUMAN 55 HtGAVLDCAfYDPTHAW--SGGLDHQLKMH 82 7555988888*******..8**9***9985 PP == domain 3 score: 24.7 bits; conditional E-value: 1.9e-06 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++++ ++p+ + +++Gs+D+tv++Wd sp|O43684|BUB3_HUMAN 94 THdAPIRCVEYCPEVNVMVTGSWDQTVKLWD 124 68777*************************9 PP == domain 4 score: 16.3 bits; conditional E-value: 0.00084 ESS..SS........EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ss........vtslafspdgawlasGsdDgtvriWd 38 + H + v++++f+ ++ +a+G+ Dg v iWd sp|O43684|BUB3_HUMAN 222 KCHrlKEnnieqiypVNAISFHNIHNTFATGGSDGFVNIWD 262 5555433445666669***************88*******9 PP == domain 5 score: 7.0 bits; conditional E-value: 0.7 S...SSEEEEEEETTSSEEEEEE CS WD40 10 H...ssvtslafspdgawlasGs 29 H +s+ slafs dg+ la +s sp|O43684|BUB3_HUMAN 273 HrypTSIASLAFSNDGTTLAIAS 295 54445699**********98443 PP >> sp|Q8NHY2|RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2 OS=Homo sapiens GN=RFWD2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 7.7 6.2e+02 9 37 .. 420 448 .. 407 449 .. 0.81 2 ! 13.9 0.1 0.0048 0.39 10 38 .] 470 499 .. 461 499 .. 0.80 3 ! 14.7 0.0 0.0026 0.21 2 38 .] 504 542 .. 503 542 .. 0.81 4 ? 12.5 0.1 0.013 1.1 12 38 .] 557 584 .. 547 584 .. 0.81 5 ! 13.0 0.0 0.0088 0.71 2 38 .] 590 626 .. 589 626 .. 0.79 6 ! 14.3 0.0 0.0035 0.29 3 37 .. 632 667 .. 630 667 .. 0.86 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 7.7 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 G s v+s+ f++d +++a ++ ++++++ sp|Q8NHY2|RFWD2_HUMAN 420 GS-SiVSSIEFDRDCDYFAIAGVTKKIKVY 448 44.348***********9977779999887 PP == domain 2 score: 13.9 bits; conditional E-value: 0.0048 SSSEEEEEEETTSSEEEEEET.TSEEEEEE CS WD40 10 HssvtslafspdgawlasGsd.DgtvriWd 38 s ++++++s++++ l+++sd gtv +Wd sp|Q8NHY2|RFWD2_HUMAN 470 NSKISCISWSSYHKNLLASSDyEGTVILWD 499 4449****99999998777644*******9 PP == domain 3 score: 14.7 bits; conditional E-value: 0.0026 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 q +++ H + +s++ + d ++lasGsdD +v++W+ sp|Q8NHY2|RFWD2_HUMAN 504 QRSKVYQEHeKRCWSVDfNLMDPKLLASGSDDAKVKLWS 542 566889999888999976556666699***********5 PP == domain 4 score: 12.5 bits; conditional E-value: 0.013 SEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 12 svtslafspdgawlas.GsdDgtvriWd 38 +v++++fsp+++++++ G+ D+ v+ +d sp|Q8NHY2|RFWD2_HUMAN 557 NVCCVKFSPSSRYHLAfGCADHCVHYYD 584 49***********7655778***99876 PP == domain 5 score: 13.0 bits; conditional E-value: 0.0088 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q++ +++GH + v s a +g ++s+s D +++W+ sp|Q8NHY2|RFWD2_HUMAN 590 QPIMVFKGHrKAV-SYAKFVSGEEIVSASTDSQLKLWN 626 7999*****999*.6655555555677888*******8 PP == domain 6 score: 14.3 bits; conditional E-value: 0.0035 EEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ss...vtslafspdgawlasGsdDgtvriW 37 clr+++GH + v +l ++g+++a+Gs++++++++ sp|Q8NHY2|RFWD2_HUMAN 632 CLRSFKGHiNEknfV-GL--ASNGDYIACGSENNSLYLY 667 9*******9555557.88..99***********999875 PP >> tr|H0YA24|H0YA24_HUMAN Pleiotropic regulator 1 (Fragment) OS=Homo sapiens GN=PLRG1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.1 5.6e-07 4.5e-05 2 38 .] 9 46 .. 8 46 .. 0.93 2 ! 28.1 0.5 1.5e-07 1.2e-05 2 38 .] 51 88 .. 50 88 .. 0.95 3 ! 26.1 0.1 6.6e-07 5.4e-05 3 38 .] 94 130 .. 92 130 .. 0.77 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 5.6e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +ltGH s v+++ +s +++l+s+++D+ v+ Wd tr|H0YA24|H0YA24_HUMAN 9 KLKLSLTGHiSTVRGVIVSTRSPYLFSCGEDKQVKCWD 46 566799****99*************************9 PP == domain 2 score: 28.1 bits; conditional E-value: 1.5e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r++ GH s v++l+ +p + l+++s+D t riWd tr|H0YA24|H0YA24_HUMAN 51 KVIRHYHGHlSAVYGLDLHPTIDVLVTCSRDSTARIWD 88 5689*********************************9 PP == domain 3 score: 26.1 bits; conditional E-value: 6.6e-07 EEEEEESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 ++tl+GH + v+++ + +++Gs D t+r+Wd tr|H0YA24|H0YA24_HUMAN 94 SVHTLSGHtNAvatVRCQ---AAEPQIITGSHDTTIRLWD 130 58******8885555666...44444789*99*******9 PP >> sp|Q8TEQ6|GEMI5_HUMAN Gem-associated protein 5 OS=Homo sapiens GN=GEMIN5 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.2 0.00012 0.0098 4 38 .] 57 95 .. 54 95 .. 0.71 2 ! 18.5 0.3 0.00016 0.013 2 38 .] 186 255 .. 185 255 .. 0.65 3 ? 8.8 0.0 0.2 16 12 38 .] 335 365 .. 323 365 .. 0.80 4 ? 4.9 0.0 3.2 2.6e+02 25 38 .] 395 408 .. 375 408 .. 0.77 5 ? 3.9 0.1 6.8 5.5e+02 13 38 .] 429 455 .. 419 455 .. 0.80 6 ! 24.8 0.3 1.7e-06 0.00013 3 38 .] 631 668 .. 629 668 .. 0.86 7 ? 8.0 0.1 0.34 28 2 37 .. 673 710 .. 672 710 .. 0.75 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 0.00012 EEEEESS.SSEEEEE..EETTSSE...EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla..fspdgaw...lasGsdDgtvriWd 38 +++l GH v+++ + a++sdDgtv+iWd sp|Q8TEQ6|GEMI5_HUMAN 57 IGELVGHtERVSGFTfsH--HPGQynlCATSSDDGTVKIWD 95 67899**66699998532..333346457899********9 PP == domain 2 score: 18.5 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEE................................EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla................................fspdgawlasGsdDgtvriWd 38 + ++ l+GH + ++s+a g +la+Gs+D+t+riW+ sp|Q8TEQ6|GEMI5_HUMAN 186 EVIHRLRGHdDEIHSIAwcplpgedclsinqeetseeaeitngnavaqaPVTKGCYLATGSKDQTIRIWS 255 67899999955599996555555555555555555555555544444444445555*************5 PP == domain 3 score: 8.8 bits; conditional E-value: 0.2 S.EEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 12 s.vtsla...fspdgawlasGsdDgtvriWd 38 v l+ + +d+++l+s s+D+ v+ Wd sp|Q8TEQ6|GEMI5_HUMAN 335 RiVFNLCplqTEDDKQLLLSTSMDRDVKCWD 365 345777777789999***99999*******9 PP == domain 4 score: 4.9 bits; conditional E-value: 3.2 EEEE.ETTSEEEEEE CS WD40 25 lasG.sdDgtvriWd 38 la G + Dg +r+W+ sp|Q8TEQ6|GEMI5_HUMAN 395 LAIGvG-DGMIRVWN 408 566867.*******8 PP == domain 5 score: 3.9 bits; conditional E-value: 6.8 EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw.lasGsdDgtvriWd 38 vt+l+++p + la G+dDg+v ++d sp|Q8TEQ6|GEMI5_HUMAN 429 VTALCWHPTKEGcLAFGTDDGKVGLYD 455 9****99999994444999**998887 PP == domain 6 score: 24.8 bits; conditional E-value: 1.7e-06 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + rtl+GH +ts+a+sp+++ l+s+s+Dgt +Wd sp|Q8TEQ6|GEMI5_HUMAN 631 PYRTLSGHtAKITSVAWSPHHDGrLVSASYDGTAQVWD 668 679*****666*****88888887778999*******9 PP == domain 7 score: 8.0 bits; conditional E-value: 0.34 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 ++l ++GH + ++a+sp + + sG dD v+ W sp|Q8TEQ6|GEMI5_HUMAN 673 EPLCNFRGHrGRLLCVAWSPLDPDcIYSGADDFCVHKW 710 68899****88899**8555444445699999888766 PP >> tr|H3BPT1|H3BPT1_HUMAN Target of rapamycin complex subunit LST8 OS=Homo sapiens GN=MLST8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.043 3.5 24 37 .. 14 27 .. 7 28 .. 0.82 2 ! 14.8 0.0 0.0025 0.2 3 38 .] 34 69 .. 32 69 .. 0.86 3 ! 24.4 0.1 2.3e-06 0.00019 6 38 .] 80 113 .. 75 113 .. 0.82 4 ! 21.8 0.0 1.5e-05 0.0012 2 38 .] 120 156 .. 119 156 .. 0.96 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.043 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W tr|H3BPT1|H3BPT1_HUMAN 14 ILATAGYDHTVRFW 27 5888888******* PP == domain 2 score: 14.8 bits; conditional E-value: 0.0025 EEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 c+rt H s v++l + pd +++a+++ +++r++d tr|H3BPT1|H3BPT1_HUMAN 34 CTRTVQ-HqdSQVNALEVTPDRSMIAAAG-YQHIRMYD 69 788875.75444**************99*.******98 PP == domain 3 score: 24.4 bits; conditional E-value: 2.3e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd tr|H3BPT1|H3BPT1_HUMAN 80 SYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 113 5555445688999********************9 PP == domain 4 score: 21.8 bits; conditional E-value: 1.5e-05 EEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtslafspdgawlasGsdDgtvriWd 38 qc+r++ ++++++ +p++a l+ G+ g ++iWd tr|H3BPT1|H3BPT1_HUMAN 120 QCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWD 156 8******9999*************************9 PP >> sp|P57737-2|CORO7_HUMAN Isoform 2 of Coronin-7 OS=Homo sapiens GN=CORO7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 0.013 1 5 38 .] 77 111 .. 69 111 .. 0.81 2 ? 10.9 0.0 0.042 3.4 12 37 .. 461 487 .. 453 488 .. 0.85 3 ! 23.0 0.0 6.1e-06 0.00049 4 38 .] 502 538 .. 499 538 .. 0.85 4 ! 24.1 0.0 2.8e-06 0.00023 7 37 .. 548 579 .. 544 580 .. 0.90 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +l +H++ v s +s+dga++ ++++D+ +ri+d sp|P57737-2|CORO7_HUMAN 77 SELAAHGDlVQSAVWSRDGALVGTACKDKQLRIFD 111 45667866899999*******856789******98 PP == domain 2 score: 10.9 bits; conditional E-value: 0.042 SEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriW 37 vt+la++p + la +++D +r+W sp|P57737-2|CORO7_HUMAN 461 AVTDLAWDPFDPHrLAVAGEDARIRLW 487 49***********9887888******* PP == domain 3 score: 23.0 bits; conditional E-value: 6.1e-06 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ltGH ++sl+f+p a ++ s+s+D tvriWd sp|P57737-2|CORO7_HUMAN 502 ETVLTGHtEKICSLRFHPLAANVLaSSSYDLTVRIWD 538 5789***666************7527789*******9 PP == domain 4 score: 24.1 bits; conditional E-value: 2.8e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH + + sla+spdg+ la+ ++Dg vr++ sp|P57737-2|CORO7_HUMAN 548 LQGHqDQIFSLAWSPDGQQLATVCKDGRVRVY 579 78**666***************9*******98 PP >> sp|Q9BVC4-4|LST8_HUMAN Isoform 3 of Target of rapamycin complex subunit LST8 OS=Homo sapiens GN=MLST8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.041 3.4 24 37 .. 33 46 .. 17 47 .. 0.84 2 ! 14.6 0.0 0.0029 0.24 3 38 .] 53 88 .. 51 88 .. 0.86 3 ! 24.2 0.1 2.7e-06 0.00022 6 38 .] 99 132 .. 94 132 .. 0.82 4 ! 21.6 0.0 1.7e-05 0.0014 2 38 .] 139 175 .. 138 175 .. 0.96 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.041 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W sp|Q9BVC4-4|LST8_HUMAN 33 ILATAGYDHTVRFW 46 5888888******* PP == domain 2 score: 14.6 bits; conditional E-value: 0.0029 EEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 c+rt H s v++l + pd +++a+++ +++r++d sp|Q9BVC4-4|LST8_HUMAN 53 CTRTVQ-HqdSQVNALEVTPDRSMIAAAG-YQHIRMYD 88 788875.75444**************99*.******98 PP == domain 3 score: 24.2 bits; conditional E-value: 2.7e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd sp|Q9BVC4-4|LST8_HUMAN 99 SYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 132 5555445688999********************9 PP == domain 4 score: 21.6 bits; conditional E-value: 1.7e-05 EEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtslafspdgawlasGsdDgtvriWd 38 qc+r++ ++++++ +p++a l+ G+ g ++iWd sp|Q9BVC4-4|LST8_HUMAN 139 QCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWD 175 8******9999*************************9 PP >> tr|H0YEF1|H0YEF1_HUMAN Jouberin (Fragment) OS=Homo sapiens GN=AHI1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.1 0.63 51 15 32 .. 12 31 .. 6 32 .. 0.80 2 ! 29.2 0.3 7e-08 5.7e-06 2 38 .] 43 80 .. 42 80 .. 0.91 3 ? 11.6 0.0 0.026 2.1 12 38 .] 97 124 .. 85 124 .. 0.66 4 ! 14.6 0.6 0.0027 0.22 4 38 .] 135 170 .. 133 170 .. 0.90 5 ! 13.6 0.0 0.0057 0.47 19 38 .] 250 269 .. 233 269 .. 0.89 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.63 EEEEETTSSEEEEE..ETTS CS WD40 15 slafspdgawlasG..sdDg 32 +l+fs++g+ la++ s+Dg tr|H0YEF1|H0YEF1_HUMAN 12 CLDFSHNGRILAAAcaSRDG 31 99********9854247898 PP == domain 2 score: 29.2 bits; conditional E-value: 7e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r+l GH + +++l++s+d ++++++s Dgt riW+ tr|H0YEF1|H0YEF1_HUMAN 43 RFMRELCGHlNIIYDLSWSKDDHYILTSSSDGTARIWK 80 5689999**999************998877*******6 PP == domain 3 score: 11.6 bits; conditional E-value: 0.026 SEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriWd 38 +v+ +f+p + +++G++D +riW+ tr|H0YEF1|H0YEF1_HUMAN 97 FVYTAKFHPAVRElVVTGCYDSMIRIWK 124 4444444444444178***********6 PP == domain 4 score: 14.6 bits; conditional E-value: 0.0027 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r ++ H s+++sl+f+ +g+ + sG+ g + +W+ tr|H0YEF1|H0YEF1_HUMAN 135 VRQFDVHkSFINSLCFDTEGHHMYSGDCTGVIVVWN 170 688999*777****************77*******8 PP == domain 5 score: 13.6 bits; conditional E-value: 0.0057 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 p g++l++Gs+Dg v++W+ tr|H0YEF1|H0YEF1_HUMAN 250 TPCGTFLFAGSEDGIVYVWN 269 6999***************8 PP >> tr|K7EIK7|K7EIK7_HUMAN Echinoderm microtubule-associated protein-like 2 OS=Homo sapiens GN=EML2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.1 0.0014 0.11 2 38 .] 96 143 .. 95 143 .. 0.80 2 ? 3.4 0.0 9.7 7.8e+02 18 37 .. 213 232 .. 196 233 .. 0.74 3 ? 5.4 0.0 2.3 1.8e+02 7 37 .. 246 278 .. 240 278 .. 0.82 4 ! 14.2 0.1 0.0039 0.31 4 37 .. 287 321 .. 284 321 .. 0.89 5 ! 14.1 0.1 0.0039 0.32 8 38 .] 374 405 .. 365 405 .. 0.89 6 ! 15.5 0.1 0.0015 0.12 9 37 .. 459 487 .. 449 488 .. 0.81 7 ! 13.8 1.5 0.0051 0.42 4 38 .] 499 534 .. 497 534 .. 0.86 8 ? 5.7 0.1 1.9 1.5e+02 11 31 .. 574 593 .. 563 596 .. 0.82 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 0.0014 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 q +r++ GH +++ +la +pd +a+G + ++vriWd tr|K7EIK7|K7EIK7_HUMAN 96 QRQRHYLGHnDDIKCLAIHPDMVTIATGqvaGTtkegkplPPHVRIWD 143 779******666*************99754422457778899999998 PP == domain 2 score: 3.4 bits; conditional E-value: 9.7 EETTSSE.EEEEETTSEEEEE CS WD40 18 fspdgaw.lasGsdDgtvriW 37 f+p + l++++ + ++++W tr|K7EIK7|K7EIK7_HUMAN 213 FHPTDPTvLITCG-KSHIYFW 232 77777773569**.******* PP == domain 3 score: 5.4 bits; conditional E-value: 2.3 EESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ss..vtslafspdgawlasGsdDgtvriW 37 ++ H ++ v ++ f g+ + +G+ g++++W tr|K7EIK7|K7EIK7_HUMAN 246 FEKHeKPkyVLCVTFLEGGDVV-TGDSGGNLYVW 278 677987788****999999996.7*66******9 PP == domain 4 score: 14.2 bits; conditional E-value: 0.0039 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l +H ++v +l+ +dg++++ G++D+ v +W tr|K7EIK7|K7EIK7_HUMAN 287 QAVLGAHdGGVFGLCALRDGTLVSGGGRDRRVVLW 321 67899**777************97668******** PP == domain 5 score: 14.1 bits; conditional E-value: 0.0039 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++la++p+ a +++++ D+ v++W+ tr|K7EIK7|K7EIK7_HUMAN 374 QGHvEELWGLATHPSRAQFVTCGQDKLVHLWS 405 5998889************************5 PP == domain 6 score: 15.5 bits; conditional E-value: 0.0015 SSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriW 37 G ++ ++fspdga+la Gs D+ v+++ tr|K7EIK7|K7EIK7_HUMAN 459 GNEQISVVSFSPDGAYLAVGSHDNLVYVY 487 333387889***********99**99987 PP == domain 7 score: 13.8 bits; conditional E-value: 0.0051 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++++GH s++t+l++ +d++ +++ s D + Wd tr|K7EIK7|K7EIK7_HUMAN 499 LGKCSGHsSFITHLDWAQDSSCFVTNSGDYEILYWD 534 67899**777************997555****9998 PP == domain 8 score: 5.7 bits; conditional E-value: 1.9 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 ++++++a s+dg++las++ D tr|K7EIK7|K7EIK7_HUMAN 574 TDINAVARSHDGKLLASAD-D 593 36*************9876.6 PP >> tr|H0YEU5|H0YEU5_HUMAN Histone-binding protein RBBP4 (Fragment) OS=Homo sapiens GN=RBBP4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.8 0.0 4.8e-09 3.9e-07 2 38 .] 2 40 .. 1 40 [. 0.90 2 ! 23.2 0.1 5.5e-06 0.00044 4 38 .] 48 84 .. 46 84 .. 0.85 3 ! 21.0 0.1 2.7e-05 0.0022 4 37 .. 105 140 .. 102 141 .. 0.85 Alignments for each domain: == domain 1 score: 32.8 bits; conditional E-value: 4.8e-09 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++ ++H v++l+f+p++ ++ a+Gs D+tv +Wd tr|H0YEU5|H0YEU5_HUMAN 2 KPSHSVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 40 68899****777************6379**********9 PP == domain 2 score: 23.2 bits; conditional E-value: 5.5e-06 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l++++ H++ + +++sp++ ++ s++ D+ + +Wd tr|H0YEU5|H0YEU5_HUMAN 48 LHSFESHKDeIFQVQWSPHNETILaSSGTDRRLNVWD 84 89*****556************7525567*******9 PP == domain 3 score: 21.0 bits; conditional E-value: 2.7e-05 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ +W tr|H0YEU5|H0YEU5_HUMAN 105 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQVW 140 56668**666************9977799*****99 PP >> tr|B4DRT0|B4DRT0_HUMAN Histone-binding protein RBBP4 OS=Homo sapiens GN=RBBP4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.8 0.0 5.1e-09 4.2e-07 2 38 .] 12 50 .. 11 50 .. 0.90 2 ! 23.1 0.1 5.8e-06 0.00047 4 38 .] 58 94 .. 56 94 .. 0.85 3 ! 20.9 0.1 2.9e-05 0.0024 4 37 .. 115 150 .. 112 151 .. 0.85 Alignments for each domain: == domain 1 score: 32.8 bits; conditional E-value: 5.1e-09 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++ ++H v++l+f+p++ ++ a+Gs D+tv +Wd tr|B4DRT0|B4DRT0_HUMAN 12 KPSHSVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 50 68899****777************6379**********9 PP == domain 2 score: 23.1 bits; conditional E-value: 5.8e-06 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l++++ H++ + +++sp++ ++ s++ D+ + +Wd tr|B4DRT0|B4DRT0_HUMAN 58 LHSFESHKDeIFQVQWSPHNETILaSSGTDRRLNVWD 94 89*****556************7525567*******9 PP == domain 3 score: 20.9 bits; conditional E-value: 2.9e-05 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ +W tr|B4DRT0|B4DRT0_HUMAN 115 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQVW 150 56668**666************9977799****999 PP >> sp|O43379-2|WDR62_HUMAN Isoform 2 of WD repeat-containing protein 62 OS=Homo sapiens GN=WDR62 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.0 7.4e-05 0.006 2 38 .] 102 141 .. 101 141 .. 0.90 2 ! 13.0 0.0 0.009 0.73 6 38 .] 150 185 .. 145 185 .. 0.80 3 ? 10.4 0.1 0.058 4.7 13 37 .. 201 224 .. 192 224 .. 0.88 4 ? 6.7 0.0 0.9 73 15 37 .. 302 320 .. 291 321 .. 0.75 5 ! 15.1 0.1 0.002 0.16 15 38 .] 364 387 .. 348 387 .. 0.84 6 ! 16.4 0.1 0.00075 0.061 18 38 .] 422 441 .. 397 441 .. 0.74 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 7.4e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++++++ + +s ++lafspdg+++++G + + vriWd sp|O43379-2|WDR62_HUMAN 102 KQQHIFNTArKSLSALAFSPDGKYIVTGenGHRPAVRIWD 141 678999988899***************98866*******9 PP == domain 2 score: 13.0 bits; conditional E-value: 0.009 EEESSSS.EEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlas.G..sdDgtvriWd 38 + GH+ v ++afsp+ + ++s G + D + +Wd sp|O43379-2|WDR62_HUMAN 150 EMLGHKYgVACVAFSPNMKHIVSmGyqH-DMVLNVWD 185 5569*555************99656444.*******9 PP == domain 3 score: 10.4 bits; conditional E-value: 0.058 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 v +l+fs d++++++ + +++vr+W sp|O43379-2|WDR62_HUMAN 201 VIALSFSEDSSYFVTVG-NRHVRFW 224 45899**********9*.******* PP == domain 4 score: 6.7 bits; conditional E-value: 0.9 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ ++ ++++G+ Dg vri+ sp|O43379-2|WDR62_HUMAN 302 CV----SQELIFCGCTDGIVRIF 320 33....5566779999*****97 PP == domain 5 score: 15.1 bits; conditional E-value: 0.002 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +l f+p ++wl++ +D++++iWd sp|O43379-2|WDR62_HUMAN 364 ALTFDPIHQWLSCVYKDHSIYIWD 387 788*******976699*******9 PP == domain 6 score: 16.4 bits; conditional E-value: 0.00075 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 p+g++l+++s D+t+r+W+ sp|O43379-2|WDR62_HUMAN 422 CLPSGSFLTCSS-DNTIRFWN 441 679****98777.*******8 PP >> tr|E7EQK3|E7EQK3_HUMAN WD repeat-containing protein 49 OS=Homo sapiens GN=WDR49 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 4.4 3.6e+02 12 38 .] 74 100 .. 64 100 .. 0.85 2 ? 11.3 0.0 0.032 2.6 2 38 .] 106 143 .. 105 143 .. 0.88 3 ? 3.4 0.0 9.5 7.7e+02 7 37 .. 197 228 .. 192 229 .. 0.74 4 ! 21.7 0.0 1.7e-05 0.0013 2 38 .] 234 273 .. 233 273 .. 0.85 5 ! 15.9 0.0 0.0011 0.087 10 38 .] 346 374 .. 341 374 .. 0.89 6 ? 6.4 0.0 1.1 91 22 38 .] 454 469 .. 421 469 .. 0.82 7 ? 10.6 0.0 0.052 4.3 2 38 .] 474 512 .. 473 512 .. 0.87 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 4.4 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +++++++++ +++a+++ +++v +W+ tr|E7EQK3|E7EQK3_HUMAN 74 GIHAFDYHSRLNLIATAGINNKVCLWN 100 5888989999999*************8 PP == domain 2 score: 11.3 bits; conditional E-value: 0.032 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++l GH sv +++f + + l+s s+D+ +r+Wd tr|E7EQK3|E7EQK3_HUMAN 106 KPVGVLWGHsASVIAVQFFVERKQLFSFSKDKVLRLWD 143 6788899**77788**99999999**88*********9 PP == domain 3 score: 3.4 bits; conditional E-value: 9.5 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + H + vt++ +++ + ++s++ tv +W tr|E7EQK3|E7EQK3_HUMAN 197 VKSHeKAVTCVLYNSILKQVISSDTGSTVSFW 228 5789999****655555558877668888888 PP == domain 4 score: 21.7 bits; conditional E-value: 1.7e-05 EEEEEEE.SS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtlt.GH.ss.vtslafspdgawlasGsdDgtvriWd 38 q+++ +t H + ++ +a + + + l++Gs Dgtv+iWd tr|E7EQK3|E7EQK3_HUMAN 234 QKIKQFTgCHgNAeISTMALDANETRLLTGSTDGTVKIWD 273 67777874666558*************************9 PP == domain 5 score: 15.9 bits; conditional E-value: 0.0011 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ + af p ++++ +Gs+Dg + +W+ tr|E7EQK3|E7EQK3_HUMAN 346 HhDDILCAAFLPPQTLV-TGSYDGEIVLWN 374 4488************7.7**********8 PP == domain 6 score: 6.4 bits; conditional E-value: 1.1 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 +++++G+ g vr+Wd tr|E7EQK3|E7EQK3_HUMAN 454 ANLVSCGG-SGYVRFWD 469 35566677.*******9 PP == domain 7 score: 10.6 bits; conditional E-value: 0.052 EEEEEEESSSSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla..fspdgawlasGsdDgtvriWd 38 q+l ++ +Hs+v s+ +++ +++l++G+ Dg ++iW+ tr|E7EQK3|E7EQK3_HUMAN 474 QLLAEFLAHSGVGSIImsTDKMNRYLTTGDLDGWLKIWN 512 6788899998898888778888999****99*******8 PP >> tr|H0Y8A5|H0Y8A5_HUMAN WD repeat-containing protein 49 (Fragment) OS=Homo sapiens GN=WDR49 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 4.5 3.7e+02 12 38 .] 86 112 .. 76 112 .. 0.85 2 ? 11.2 0.0 0.032 2.6 2 38 .] 118 155 .. 117 155 .. 0.88 3 ? 3.4 0.0 9.7 7.8e+02 7 37 .. 209 240 .. 204 241 .. 0.74 4 ! 21.6 0.0 1.7e-05 0.0014 2 38 .] 246 285 .. 245 285 .. 0.85 5 ! 15.9 0.0 0.0011 0.089 10 38 .] 358 386 .. 353 386 .. 0.89 6 ? 6.3 0.0 1.2 93 22 38 .] 466 481 .. 434 481 .. 0.81 7 ? 10.5 0.0 0.054 4.3 2 38 .] 486 524 .. 485 524 .. 0.87 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 4.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +++++++++ +++a+++ +++v +W+ tr|H0Y8A5|H0Y8A5_HUMAN 86 GIHAFDYHSRLNLIATAGINNKVCLWN 112 5888989999999*************8 PP == domain 2 score: 11.2 bits; conditional E-value: 0.032 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++l GH sv +++f + + l+s s+D+ +r+Wd tr|H0Y8A5|H0Y8A5_HUMAN 118 KPVGVLWGHsASVIAVQFFVERKQLFSFSKDKVLRLWD 155 6788899**77788**99999999**88*********9 PP == domain 3 score: 3.4 bits; conditional E-value: 9.7 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + H + vt++ +++ + ++s++ tv +W tr|H0Y8A5|H0Y8A5_HUMAN 209 VKSHeKAVTCVLYNSILKQVISSDTGSTVSFW 240 5789999****655555558877668888888 PP == domain 4 score: 21.6 bits; conditional E-value: 1.7e-05 EEEEEEE.SS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtlt.GH.ss.vtslafspdgawlasGsdDgtvriWd 38 q+++ +t H + ++ +a + + + l++Gs Dgtv+iWd tr|H0Y8A5|H0Y8A5_HUMAN 246 QKIKQFTgCHgNAeISTMALDANETRLLTGSTDGTVKIWD 285 67777874666558*************************9 PP == domain 5 score: 15.9 bits; conditional E-value: 0.0011 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ + af p ++++ +Gs+Dg + +W+ tr|H0Y8A5|H0Y8A5_HUMAN 358 HhDDILCAAFLPPQTLV-TGSYDGEIVLWN 386 4488************7.7**********8 PP == domain 6 score: 6.3 bits; conditional E-value: 1.2 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 +++++G+ g vr+Wd tr|H0Y8A5|H0Y8A5_HUMAN 466 ANLVSCGG-SGYVRFWD 481 35566677.*******9 PP == domain 7 score: 10.5 bits; conditional E-value: 0.054 EEEEEEESSSSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla..fspdgawlasGsdDgtvriWd 38 q+l ++ +Hs+v s+ +++ +++l++G+ Dg ++iW+ tr|H0Y8A5|H0Y8A5_HUMAN 486 QLLAEFLAHSGVGSIImsTDKMNRYLTTGDLDGWLKIWN 524 6788899998898888778888999****99*******8 PP >> tr|H0YCT5|H0YCT5_HUMAN Histone-binding protein RBBP4 (Fragment) OS=Homo sapiens GN=RBBP4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.7 0.0 5.5e-09 4.4e-07 2 38 .] 19 57 .. 18 57 .. 0.90 2 ! 23.0 0.1 6.2e-06 0.00051 4 38 .] 65 101 .. 63 101 .. 0.85 3 ! 20.8 0.1 3.1e-05 0.0025 4 37 .. 122 157 .. 119 158 .. 0.85 Alignments for each domain: == domain 1 score: 32.7 bits; conditional E-value: 5.5e-09 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++ ++H v++l+f+p++ ++ a+Gs D+tv +Wd tr|H0YCT5|H0YCT5_HUMAN 19 KPSHSVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 57 68899****777************6379**********9 PP == domain 2 score: 23.0 bits; conditional E-value: 6.2e-06 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l++++ H++ + +++sp++ ++ s++ D+ + +Wd tr|H0YCT5|H0YCT5_HUMAN 65 LHSFESHKDeIFQVQWSPHNETILaSSGTDRRLNVWD 101 89*****556************7525567*******9 PP == domain 3 score: 20.8 bits; conditional E-value: 3.1e-05 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ +W tr|H0YCT5|H0YCT5_HUMAN 122 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQVW 157 56668**666************9977799****999 PP >> tr|H0Y500|H0Y500_HUMAN Bromodomain and WD repeat-containing protein 1 (Fragment) OS=Homo sapiens GN=BRWD1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.1 4 3.2e+02 25 37 .. 2 13 .. 1 14 [. 0.83 2 ? 9.0 0.0 0.17 13 17 37 .. 43 63 .. 30 63 .. 0.87 3 ! 23.3 0.0 5.1e-06 0.00041 4 37 .. 73 107 .. 70 108 .. 0.89 4 ? 9.7 0.0 0.1 8.1 13 38 .] 141 166 .. 129 166 .. 0.90 5 ! 17.2 0.1 0.00043 0.035 1 38 [] 170 209 .. 170 209 .. 0.75 6 ? 11.0 0.2 0.039 3.2 7 32 .. 225 248 .. 214 255 .. 0.77 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 4 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 +++G Dgtv +W tr|H0Y500|H0Y500_HUMAN 2 VSTGA-DGTVCFW 13 46788.******* PP == domain 2 score: 9.0 bits; conditional E-value: 0.17 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 +fs g +la+Gs D+ +r++ tr|H0Y500|H0Y500_HUMAN 43 SFSVGGMFLATGSTDHVIRMY 63 5999999************86 PP == domain 3 score: 23.3 bits; conditional E-value: 5.1e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+ H + v s++f+ +g+ ++sGs+Dgt riW tr|H0Y500|H0Y500_HUMAN 73 IAELESHtDKVDSIQFCNNGDRFLSGSRDGTARIW 107 678999*555************************* PP == domain 4 score: 9.7 bits; conditional E-value: 0.1 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 vt +a++++ + ++++ D+ +++W+ tr|H0Y500|H0Y500_HUMAN 141 VTMIAWNQNDSIVVTAVNDHVLKVWN 166 77799**********988*******8 PP == domain 5 score: 17.2 bits; conditional E-value: 0.00043 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 gq+l+ l GH + v l ++p + l++G+ Dg++ iWd tr|H0Y500|H0Y500_HUMAN 170 GQLLHNLMGHaDEVFVLETHPFDSRimLSAGH-DGSIFIWD 209 68999*****6669888866666663234566.*******9 PP == domain 6 score: 11.0 bits; conditional E-value: 0.039 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fs+dg+ +a ++ D tr|H0Y500|H0Y500_HUMAN 225 GQGHGAVFDCKFSQDGQHFA-CT-DS 248 469988************97.65.43 PP >> tr|H0Y343|H0Y343_HUMAN Jouberin (Fragment) OS=Homo sapiens GN=AHI1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.51 41 14 32 .. 113 133 .. 96 134 .. 0.77 2 ! 28.8 0.3 9.1e-08 7.3e-06 2 38 .] 145 182 .. 144 182 .. 0.90 3 ? 11.2 0.0 0.033 2.7 12 38 .] 199 226 .. 187 226 .. 0.66 4 ! 14.3 0.6 0.0035 0.29 4 38 .] 237 272 .. 235 272 .. 0.90 5 ! 13.3 0.0 0.0074 0.6 19 38 .] 352 371 .. 335 371 .. 0.89 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.51 EEEEEETTSSEEEEE..ETTS CS WD40 14 tslafspdgawlasG..sdDg 32 +l+fs++g+ la++ s+Dg tr|H0Y343|H0Y343_HUMAN 113 FCLDFSHNGRILAAAcaSRDG 133 69*********9854247898 PP == domain 2 score: 28.8 bits; conditional E-value: 9.1e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r+l GH + +++l++s+d ++++++s Dgt riW+ tr|H0Y343|H0Y343_HUMAN 145 RFMRELCGHlNIIYDLSWSKDDHYILTSSSDGTARIWK 182 5689999**999************998877*******6 PP == domain 3 score: 11.2 bits; conditional E-value: 0.033 SEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriWd 38 +v+ +f+p + +++G++D +riW+ tr|H0Y343|H0Y343_HUMAN 199 FVYTAKFHPAVRElVVTGCYDSMIRIWK 226 4444444444444178***********6 PP == domain 4 score: 14.3 bits; conditional E-value: 0.0035 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r ++ H s+++sl+f+ +g+ + sG+ g + +W+ tr|H0Y343|H0Y343_HUMAN 237 VRQFDVHkSFINSLCFDTEGHHMYSGDCTGVIVVWN 272 688999*777****************77*******8 PP == domain 5 score: 13.3 bits; conditional E-value: 0.0074 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 p g++l++Gs+Dg v++W+ tr|H0Y343|H0Y343_HUMAN 352 TPCGTFLFAGSEDGIVYVWN 371 6999***************8 PP >> tr|B4DE62|B4DE62_HUMAN Transducin-like enhancer protein 2 OS=Homo sapiens GN=TLE2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.3 0.00035 0.029 3 38 .] 117 151 .. 115 151 .. 0.89 2 ? 7.6 0.0 0.47 38 12 38 .] 172 198 .. 162 198 .. 0.91 3 ! 14.9 0.2 0.0022 0.18 14 38 .] 218 242 .. 208 242 .. 0.85 4 ! 16.6 0.6 0.00065 0.052 4 38 .] 249 284 .. 246 284 .. 0.89 5 ? 7.9 0.0 0.37 30 6 34 .. 290 321 .. 286 323 .. 0.76 6 ? 10.4 0.0 0.059 4.8 10 37 .. 337 365 .. 330 366 .. 0.84 7 ? 9.2 0.0 0.15 12 11 33 .. 380 402 .. 372 407 .. 0.82 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 0.00035 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +l+tl +H+ v+++ s + + + +G+ +g v++Wd tr|B4DE62|B4DE62_HUMAN 117 QLHTL-AHGEvVCAVTISGSTQHVYTGG-KGCVKVWD 151 68888.8*6657****************.*******9 PP == domain 2 score: 7.6 bits; conditional E-value: 0.47 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|B4DE62|B4DE62_HUMAN 172 YIRSCKLLPDGRSLIVGGEASTLSIWD 198 499999********************9 PP == domain 3 score: 14.9 bits; conditional E-value: 0.0022 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la+spd + +s++ Dg++ +Wd tr|B4DE62|B4DE62_HUMAN 218 YALAVSPDAKVCFSCCSDGNIVVWD 242 6899*******887755*******9 PP == domain 4 score: 16.6 bits; conditional E-value: 0.00065 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r + GH ++ ++++ s++g+ l +G+ D+tvr Wd tr|B4DE62|B4DE62_HUMAN 249 VRQFQGHtDGASCIDISDYGTRLWTGGLDNTVRCWD 284 7889***7779***********747999*******9 PP == domain 5 score: 7.9 bits; conditional E-value: 0.37 EEESS.SS..EEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ss..vtslafspdgawlasGsdDgtv 34 l H +s + sl +p+++wla G++ +v tr|B4DE62|B4DE62_HUMAN 290 QLQQHdFSsqIFSLGHCPNQDWLAVGMESSNV 321 5667863347**************99866555 PP == domain 6 score: 10.4 bits; conditional E-value: 0.059 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W tr|B4DE62|B4DE62_HUMAN 337 HeSCVLSLKFASCGRWFVSTGKDNLLNAW 365 7778**************99999987766 PP == domain 7 score: 9.2 bits; conditional E-value: 0.15 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s++++++++Gs D++ tr|B4DE62|B4DE62_HUMAN 380 SSVLSCDISRNNKYIVTGSGDKK 402 4599**************87986 PP >> tr|H0YDK2|H0YDK2_HUMAN Histone-binding protein RBBP4 (Fragment) OS=Homo sapiens GN=RBBP4 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.1 7.7 6.2e+02 29 38 .] 7 16 .. 2 16 .. 0.78 2 ! 31.8 0.0 1e-08 8.2e-07 2 38 .] 24 62 .. 23 62 .. 0.90 3 ! 22.2 0.1 1.1e-05 0.00092 4 38 .] 70 106 .. 68 106 .. 0.85 4 ! 20.0 0.1 5.7e-05 0.0046 4 37 .. 127 162 .. 124 163 .. 0.85 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 7.7 ETTSEEEEEE CS WD40 29 sdDgtvriWd 38 dD++++iWd tr|H0YDK2|H0YDK2_HUMAN 7 ADDQKLMIWD 16 37*******9 PP == domain 2 score: 31.8 bits; conditional E-value: 1e-08 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++ ++ ++H v++l+f+p++ ++ a+Gs D+tv +Wd tr|H0YDK2|H0YDK2_HUMAN 24 KPSHSVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 62 68899****777************6379**********9 PP == domain 3 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l++++ H++ + +++sp++ ++ s++ D+ + +Wd tr|H0YDK2|H0YDK2_HUMAN 70 LHSFESHKDeIFQVQWSPHNETILaSSGTDRRLNVWD 106 89*****556************7525567*******9 PP == domain 4 score: 20.0 bits; conditional E-value: 5.7e-05 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ +W tr|H0YDK2|H0YDK2_HUMAN 127 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQVW 162 56668**666************9977799****999 PP >> sp|Q96MT7|WDR52_HUMAN WD repeat-containing protein 52 OS=Homo sapiens GN=WDR52 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 4.2 3.4e+02 16 38 .] 234 258 .. 230 258 .. 0.86 2 ? 4.2 0.0 5.3 4.3e+02 13 37 .. 275 299 .. 262 300 .. 0.79 3 ? 11.4 0.0 0.028 2.3 9 38 .] 365 393 .. 358 393 .. 0.72 4 ? 10.2 0.0 0.071 5.8 7 38 .] 466 498 .. 461 498 .. 0.84 5 ! 18.6 0.0 0.00016 0.013 3 36 .. 567 601 .. 565 603 .. 0.89 6 ? 12.7 0.2 0.012 0.94 7 38 .] 851 886 .. 848 886 .. 0.83 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 4.2 EEEETTSSEEEE.EET.TSEEEEEE CS WD40 16 lafspdgawlas.Gsd.DgtvriWd 38 ++f+ +g++las Gs D t+ iW+ sp|Q96MT7|WDR52_HUMAN 234 VDFNYSGNLLASvGSNpDYTLTIWN 258 68999*****9636668*******8 PP == domain 2 score: 4.2 bits; conditional E-value: 5.3 EEEEEEETTSSE.EEEEETTSEEEEE CS WD40 13 vtslafspdgaw.lasGsdDgtvriW 37 v + f+pd+ l++++ g++++W sp|Q96MT7|WDR52_HUMAN 275 VFKVTFNPDKEEqLTTSG-SGHIKFW 299 777889999999888889.******* PP == domain 3 score: 11.4 bits; conditional E-value: 0.028 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H ++++ + +g ++ Gs Dg vriWd sp|Q96MT7|WDR52_HUMAN 365 CHnGPINQI-MLYEGEVITVGS-DGYVRIWD 393 564447666.44455558889*.*******9 PP == domain 4 score: 10.2 bits; conditional E-value: 0.071 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ H + + ++a+sp ++a+ D++vri+d sp|Q96MT7|WDR52_HUMAN 466 FSFHsGAIEAVAVSPLTYLMATTALDCSVRIYD 498 4578445*************99888*******8 PP == domain 5 score: 18.6 bits; conditional E-value: 0.00016 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 + ++++ H +vt+la+ +dg la+Gs+D+tv + sp|Q96MT7|WDR52_HUMAN 567 LKQVFKPHtACVTALAYERDGEILATGSKDQTVFF 601 6688999*777*********************976 PP == domain 6 score: 12.7 bits; conditional E-value: 0.012 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 + H ++ + s+a+s d ++l++++ Dg++ +++ sp|Q96MT7|WDR52_HUMAN 851 FNMHdNNygcIKSIANSFDDRFLVTAGADGNIFVFN 886 55676446779*************9999****9987 PP >> sp|Q9Y4E6-2|WDR7_HUMAN Isoform 2 of WD repeat-containing protein 7 OS=Homo sapiens GN=WDR7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.4 0.0043 0.35 9 38 .] 19 47 .. 14 47 .. 0.90 2 ? 12.8 0.0 0.011 0.86 9 38 .] 62 95 .. 54 95 .. 0.92 3 ! 19.2 0.1 9.8e-05 0.0079 4 38 .] 457 498 .. 454 498 .. 0.87 4 ! 14.3 0.1 0.0034 0.27 10 37 .. 559 587 .. 550 588 .. 0.86 5 ! 22.7 0.1 7.5e-06 0.00061 2 37 .. 1353 1389 .. 1352 1390 .. 0.82 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.0043 SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriWd 38 +H +++++ +dga +++G+ Dg + +Wd sp|Q9Y4E6-2|WDR7_HUMAN 19 TH-CISAVLLTDDGATIVTGCHDGQICLWD 47 46.7899999**********99*******9 PP == domain 2 score: 12.8 bits; conditional E-value: 0.011 SS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriWd 38 GH s+t+l+ s+d+++++s+s+ g +Wd sp|Q9Y4E6-2|WDR7_HUMAN 62 GHtASITCLSkacASSDKQYIVSASESGEMCLWD 95 9*888****************************9 PP == domain 3 score: 19.2 bits; conditional E-value: 9.8e-05 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriWd 38 rtl+GH + vt+l d+++l+sG+ D +v iWd sp|Q9Y4E6-2|WDR7_HUMAN 457 HRTLRGHrNKVTCLLyphqvsARYDQRYLISGGVDFSVIIWD 498 589****999****88888777777777*************9 PP == domain 4 score: 14.3 bits; conditional E-value: 0.0034 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H +++ +++ p+ ++l+ G+ Dg+v++W sp|Q9Y4E6-2|WDR7_HUMAN 559 HlFPIQVIKWRPSDDYLVVGCSDGSVYVW 587 878898999********99977******* PP == domain 5 score: 22.7 bits; conditional E-value: 7.5e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEE.TTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs.dDgtvriW 37 +c+++ GH +++t++af pdg++la+ s D ++ +W sp|Q9Y4E6-2|WDR7_HUMAN 1353 KCQTI-HGHkGPITAVAFAPDGRYLATYSnTDSHISFW 1389 56666.6**777*************985435******* PP >> sp|O95170|CDRT1_HUMAN CMT1A duplicated region transcript 1 protein OS=Homo sapiens GN=CDRT1 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 0.0011 0.092 6 38 .] 448 481 .. 445 481 .. 0.95 2 ! 26.2 0.6 6e-07 4.9e-05 1 38 [] 485 521 .. 485 521 .. 0.88 3 ? 7.8 0.1 0.4 32 1 37 [. 525 559 .. 525 560 .. 0.89 4 ! 14.9 0.2 0.0023 0.19 2 37 .. 565 599 .. 564 600 .. 0.83 5 ? 8.3 0.0 0.27 22 2 38 .] 607 641 .. 606 641 .. 0.73 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0011 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH +sv++l + + ++l+sGs+D ++r Wd sp|O95170|CDRT1_HUMAN 448 EFRGHaGSVRALFLCEEENFLLSGSYDLSIRYWD 481 599**999*************************9 PP == domain 2 score: 26.2 bits; conditional E-value: 6e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g c+r++ GH + +t++ ++ l+sG++D+ v++Wd sp|O95170|CDRT1_HUMAN 485 GVCTRIFGGHqGTITCM------DLcknrLVSGGRDCQVKVWD 521 579*******777****......66666699***********9 PP == domain 3 score: 7.8 bits; conditional E-value: 0.4 TEEEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssv..tslafspdgawlasGsdDgtvriW 37 g+cl+t++ H +++ t + + ++++s+++ g v++W sp|O95170|CDRT1_HUMAN 525 GKCLKTFR-HkDPIlaTRI----NDTYIVSSCERGLVKVW 559 79*****9.9666778999....9*****9999******* PP == domain 4 score: 14.9 bits; conditional E-value: 0.0023 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 q+++tl+GH + v +l f +w l+sGs Dg v+ W sp|O95170|CDRT1_HUMAN 565 QLVKTLSGHeGAVKCLFF---DQWhLLSGSTDGLVMAW 599 789******888****54...477557********999 PP == domain 5 score: 8.3 bits; conditional E-value: 0.27 EEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +cl ++ H + v ++ ++ ++s++ Dg++ri++ sp|O95170|CDRT1_HUMAN 607 RCLMAFK-HpKEVLDV------SLlflrVISACADGKIRIYN 641 6777786.87888888......664555456666******98 PP >> tr|F5H8J8|F5H8J8_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (Fragment) OS=Homo sapiens G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.0 9.8e-07 8e-05 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 13.6 0.0 0.0057 0.46 12 38 .] 99 125 .. 86 125 .. 0.85 3 ? 11.8 0.2 0.021 1.7 4 33 .. 136 165 .. 133 169 .. 0.84 4 ! 20.6 0.1 3.6e-05 0.0029 2 38 .] 174 211 .. 173 211 .. 0.91 5 ? 8.6 0.1 0.23 19 1 16 [. 215 231 .. 215 232 .] 0.90 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 9.8e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ +Wd tr|F5H8J8|F5H8J8_HUMAN 48 RRTLRGHlAKIYAMHWATDSKLLVSASQDGKLIVWD 83 689****999*************************9 PP == domain 2 score: 13.6 bits; conditional E-value: 0.0057 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ tr|F5H8J8|F5H8J8_HUMAN 99 WVMTCAYAPSGNFVACGGLDNMCSIYN 125 488889******************997 PP == domain 3 score: 11.8 bits; conditional E-value: 0.021 EEEEESS.SSEEEEEEETTSSEEEEEETTSE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgt 33 r+l++H + ++++f +d++ ++s++ D t tr|F5H8J8|F5H8J8_HUMAN 136 SRELSAHtGYLSCCRFLDDNNIVTSSG-DTT 165 6899***666************98888.877 PP == domain 4 score: 20.6 bits; conditional E-value: 3.6e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+ +++ GH ++ sla+spd ++++sG D + ++Wd tr|F5H8J8|F5H8J8_HUMAN 174 QQKTVFVGHtGDCMSLAVSPDFNLFISGACDASAKLWD 211 6678899**88899**************77*******9 PP == domain 5 score: 8.6 bits; conditional E-value: 0.23 TEEEEEEESS.SSEEEE CS WD40 1 gqclrtltGH.ssvtsl 16 g+c +t+tGH s+++++ tr|F5H8J8|F5H8J8_HUMAN 215 GTCRQTFTGHeSDINAI 231 6799******999**99 PP >> sp|Q96P53|WDFY2_HUMAN WD repeat and FYVE domain-containing protein 2 OS=Homo sapiens GN=WDFY2 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 1.1 85 25 37 .. 39 51 .. 24 51 .. 0.86 2 ! 30.8 1.2 2.1e-08 1.7e-06 3 38 .] 191 227 .. 189 227 .. 0.93 3 ! 15.5 0.0 0.0014 0.12 6 38 .] 237 270 .. 233 270 .. 0.85 4 ! 17.6 0.7 0.00031 0.025 10 38 .] 363 394 .. 356 394 .. 0.79 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 1.1 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 ++s s+D+tvr+W sp|Q96P53|WDFY2_HUMAN 39 VISVSEDRTVRVW 51 456799******* PP == domain 2 score: 30.8 bits; conditional E-value: 2.1e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++t++GH ++vt+l+++p ++ l+sGs D++v +Wd sp|Q96P53|WDFY2_HUMAN 191 LVTTFRGHtGGVTALCWDPVQRVLFSGSSDHSVIMWD 227 6899****888****************99*******9 PP == domain 3 score: 15.5 bits; conditional E-value: 0.0014 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 +l GH++ v +l++ ++ + l+s++ Dg + +W+ sp|Q96P53|WDFY2_HUMAN 237 ELQGHNDrVQALSYAQHTRQLISCGGDGGIVVWN 270 589**666****99999999987766*******8 PP == domain 4 score: 17.6 bits; conditional E-value: 0.00031 S..SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H..ss.vtslafspdgawlasGsdDgtvriWd 38 H ++ + ++ f+ wl++++ D+ +++Wd sp|Q96P53|WDFY2_HUMAN 363 HdsKHnIVHVHFDATRGWLLTSGTDKVIKLWD 394 53233688**********998777*******9 PP >> sp|Q9Y4E6|WDR7_HUMAN WD repeat-containing protein 7 OS=Homo sapiens GN=WDR7 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.4 0.0044 0.36 9 38 .] 19 47 .. 14 47 .. 0.90 2 ? 12.7 0.0 0.011 0.88 9 38 .] 62 95 .. 54 95 .. 0.92 3 ! 19.2 0.1 0.0001 0.0081 4 38 .] 457 498 .. 454 498 .. 0.87 4 ! 14.3 0.1 0.0035 0.28 10 37 .. 559 587 .. 550 588 .. 0.86 5 ! 22.7 0.1 7.7e-06 0.00062 2 37 .. 1386 1422 .. 1385 1423 .. 0.82 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.0044 SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriWd 38 +H +++++ +dga +++G+ Dg + +Wd sp|Q9Y4E6|WDR7_HUMAN 19 TH-CISAVLLTDDGATIVTGCHDGQICLWD 47 46.7899999**********99*******9 PP == domain 2 score: 12.7 bits; conditional E-value: 0.011 SS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriWd 38 GH s+t+l+ s+d+++++s+s+ g +Wd sp|Q9Y4E6|WDR7_HUMAN 62 GHtASITCLSkacASSDKQYIVSASESGEMCLWD 95 9*888****************************9 PP == domain 3 score: 19.2 bits; conditional E-value: 0.0001 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriWd 38 rtl+GH + vt+l d+++l+sG+ D +v iWd sp|Q9Y4E6|WDR7_HUMAN 457 HRTLRGHrNKVTCLLyphqvsARYDQRYLISGGVDFSVIIWD 498 589****999****88888777777777*************9 PP == domain 4 score: 14.3 bits; conditional E-value: 0.0035 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H +++ +++ p+ ++l+ G+ Dg+v++W sp|Q9Y4E6|WDR7_HUMAN 559 HlFPIQVIKWRPSDDYLVVGCSDGSVYVW 587 878898999********99977******* PP == domain 5 score: 22.7 bits; conditional E-value: 7.7e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEE.TTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs.dDgtvriW 37 +c+++ GH +++t++af pdg++la+ s D ++ +W sp|Q9Y4E6|WDR7_HUMAN 1386 KCQTI-HGHkGPITAVAFAPDGRYLATYSnTDSHISFW 1422 56666.6**777*************985435******* PP >> tr|G3V1D0|G3V1D0_HUMAN Echinoderm microtubule associated protein like 3, isoform CRA_f OS=Homo sapiens GN=EML3 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.2 6.9e-06 0.00056 4 38 .] 270 315 .. 267 315 .. 0.80 2 ? 4.7 0.2 3.7 3e+02 15 38 .] 382 405 .. 354 405 .. 0.73 3 ? 8.2 0.0 0.29 23 9 37 .. 484 513 .. 477 513 .. 0.87 4 ! 18.8 0.3 0.00014 0.011 7 38 .] 565 597 .. 561 597 .. 0.88 5 ? 10.2 0.0 0.071 5.7 16 37 .. 658 679 .. 645 680 .. 0.86 6 ! 18.5 0.7 0.00017 0.014 9 38 .] 696 726 .. 688 726 .. 0.86 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 6.9e-06 EEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 +r+++GH ++v++la++pdg +asG + + v+iWd tr|G3V1D0|G3V1D0_HUMAN 270 QRHYRGHtDCVRCLAVHPDGVRVASGqtaGVdkdgkplQPVVHIWD 315 89*****777**************9874432466778888888887 PP == domain 2 score: 4.7 bits; conditional E-value: 3.7 EEE.EETTSSEEEEEETTSEEEEEE CS WD40 15 sla.fspdgawlasGsdDgtvriWd 38 ++ +++d++ +++++ + +v++W+ tr|G3V1D0|G3V1D0_HUMAN 382 AVGfNPRDSSCIVTSG-KSHVHFWN 405 3434566777799999.*******8 PP == domain 3 score: 8.2 bits; conditional E-value: 0.29 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +s+ +l+ +dg+ l+ G++D+ + W tr|G3V1D0|G3V1D0_HUMAN 484 AHeGSIFALCLRRDGTVLSGGGRDRRLVQW 513 68888************97678****9999 PP == domain 4 score: 18.8 bits; conditional E-value: 0.00014 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH + ++l+++p+++ +++++ D+ + +Wd tr|G3V1D0|G3V1D0_HUMAN 565 IQGHtDELWGLCTHPSQNRFLTCGHDRQLCLWD 597 56**666************998877*******9 PP == domain 5 score: 10.2 bits; conditional E-value: 0.071 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +++spdg +la Gs D+ ++i+ tr|G3V1D0|G3V1D0_HUMAN 658 VRYSPDGLYLAIGSHDNVIYIY 679 569**********99*****98 PP == domain 6 score: 18.5 bits; conditional E-value: 0.00017 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH s++t+l++s+dg++++s s D + Wd tr|G3V1D0|G3V1D0_HUMAN 696 GHsSFITHLDWSKDGNFIMSNSGDYEILYWD 726 9*777*************97555*****998 PP >> tr|H0Y811|H0Y811_HUMAN Sperm-associated antigen 16 protein (Fragment) OS=Homo sapiens GN=SPAG16 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.032 2.6 6 33 .. 33 61 .. 28 64 .. 0.82 2 ! 30.6 0.1 2.6e-08 2.1e-06 2 38 .] 93 130 .. 92 130 .. 0.93 3 ! 16.2 0.2 0.0009 0.073 3 38 .] 136 172 .. 134 172 .. 0.93 4 ! 21.5 0.1 1.8e-05 0.0015 4 38 .] 220 255 .] 218 255 .] 0.91 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.032 EEESS.SSEEEEEEETTSSEEEEEETTSE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgt 33 +++ H +v++++ +p+++ l+s+++D+ tr|H0Y811|H0Y811_HUMAN 33 IFRLHeLPVSCVSMQPHKDILVSCGEDRL 61 56668667*****************9986 PP == domain 2 score: 30.6 bits; conditional E-value: 2.6e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c tl GH +sv+s+ f p ++ l+++s D+t+ iWd tr|H0Y811|H0Y811_HUMAN 93 RCRCTLYGHtDSVNSIEFFPFSNTLLTSSADKTLSIWD 130 688999***888****************99*******9 PP == domain 3 score: 16.2 bits; conditional E-value: 0.0009 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++l GH s+++ f+p g+++as++ g ++Wd tr|H0Y811|H0Y811_HUMAN 136 CEQSLYGHmHSINDAIFDPRGHMIASCDACGVTKLWD 172 789999**999****************99*******9 PP == domain 4 score: 21.5 bits; conditional E-value: 1.8e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++l GH + + + fs+dg l+sG+ Dgtvr W+ tr|H0Y811|H0Y811_HUMAN 220 IHKLMGHeNEAHTVVFSHDGEILFSGGSDGTVRTWS 255 68888**9999***************88*****995 PP >> tr|H0Y5I9|H0Y5I9_HUMAN Bromodomain and WD repeat-containing protein 1 (Fragment) OS=Homo sapiens GN=BRWD1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.1 4.6 3.8e+02 25 37 .. 2 13 .. 1 14 [. 0.83 2 ? 8.8 0.0 0.19 16 17 37 .. 43 63 .. 30 63 .. 0.87 3 ! 23.0 0.0 6.1e-06 0.00049 4 37 .. 73 107 .. 70 108 .. 0.89 4 ? 9.5 0.0 0.12 9.6 13 38 .] 141 166 .. 129 166 .. 0.90 5 ! 16.9 0.1 0.00051 0.041 1 38 [] 170 209 .. 170 209 .. 0.75 6 ? 10.7 0.2 0.046 3.8 7 32 .. 225 248 .. 214 255 .. 0.77 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 4.6 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 +++G Dgtv +W tr|H0Y5I9|H0Y5I9_HUMAN 2 VSTGA-DGTVCFW 13 46788.******* PP == domain 2 score: 8.8 bits; conditional E-value: 0.19 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 +fs g +la+Gs D+ +r++ tr|H0Y5I9|H0Y5I9_HUMAN 43 SFSVGGMFLATGSTDHVIRMY 63 5999999************86 PP == domain 3 score: 23.0 bits; conditional E-value: 6.1e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+ H + v s++f+ +g+ ++sGs+Dgt riW tr|H0Y5I9|H0Y5I9_HUMAN 73 IAELESHtDKVDSIQFCNNGDRFLSGSRDGTARIW 107 678999*555************************* PP == domain 4 score: 9.5 bits; conditional E-value: 0.12 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 vt +a++++ + ++++ D+ +++W+ tr|H0Y5I9|H0Y5I9_HUMAN 141 VTMIAWNQNDSIVVTAVNDHVLKVWN 166 77799**********988*******8 PP == domain 5 score: 16.9 bits; conditional E-value: 0.00051 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 gq+l+ l GH + v l ++p + l++G+ Dg++ iWd tr|H0Y5I9|H0Y5I9_HUMAN 170 GQLLHNLMGHaDEVFVLETHPFDSRimLSAGH-DGSIFIWD 209 689999****6669888866666663234566.*******9 PP == domain 6 score: 10.7 bits; conditional E-value: 0.046 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fs+dg+ +a ++ D tr|H0Y5I9|H0Y5I9_HUMAN 225 GQGHGAVFDCKFSQDGQHFA-CT-DS 248 469988************97.65.43 PP >> tr|H0Y3M3|H0Y3M3_HUMAN Echinoderm microtubule-associated protein-like 3 (Fragment) OS=Homo sapiens GN=EML3 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.2 7.1e-06 0.00057 4 38 .] 292 337 .. 289 337 .. 0.80 2 ? 4.7 0.2 3.8 3e+02 15 38 .] 404 427 .. 376 427 .. 0.73 3 ? 8.2 0.0 0.29 24 9 37 .. 506 535 .. 499 535 .. 0.87 4 ! 18.7 0.3 0.00014 0.011 7 38 .] 587 619 .. 583 619 .. 0.88 5 ? 10.1 0.0 0.073 5.9 16 37 .. 680 701 .. 667 702 .. 0.86 6 ! 18.4 0.7 0.00017 0.014 9 38 .] 718 748 .. 710 748 .. 0.86 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 7.1e-06 EEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 +r+++GH ++v++la++pdg +asG + + v+iWd tr|H0Y3M3|H0Y3M3_HUMAN 292 QRHYRGHtDCVRCLAVHPDGVRVASGqtaGVdkdgkplQPVVHIWD 337 89*****777**************9874432466778888888887 PP == domain 2 score: 4.7 bits; conditional E-value: 3.8 EEE.EETTSSEEEEEETTSEEEEEE CS WD40 15 sla.fspdgawlasGsdDgtvriWd 38 ++ +++d++ +++++ + +v++W+ tr|H0Y3M3|H0Y3M3_HUMAN 404 AVGfNPRDSSCIVTSG-KSHVHFWN 427 3434566777799999.*******8 PP == domain 3 score: 8.2 bits; conditional E-value: 0.29 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +s+ +l+ +dg+ l+ G++D+ + W tr|H0Y3M3|H0Y3M3_HUMAN 506 AHeGSIFALCLRRDGTVLSGGGRDRRLVQW 535 68888************97678****9999 PP == domain 4 score: 18.7 bits; conditional E-value: 0.00014 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH + ++l+++p+++ +++++ D+ + +Wd tr|H0Y3M3|H0Y3M3_HUMAN 587 IQGHtDELWGLCTHPSQNRFLTCGHDRQLCLWD 619 56**666************998877*******9 PP == domain 5 score: 10.1 bits; conditional E-value: 0.073 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +++spdg +la Gs D+ ++i+ tr|H0Y3M3|H0Y3M3_HUMAN 680 VRYSPDGLYLAIGSHDNVIYIY 701 569**********99*****98 PP == domain 6 score: 18.4 bits; conditional E-value: 0.00017 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH s++t+l++s+dg++++s s D + Wd tr|H0Y3M3|H0Y3M3_HUMAN 718 GHsSFITHLDWSKDGNFIMSNSGDYEILYWD 748 9*777*************97555*****998 PP >> tr|K7EIR0|K7EIR0_HUMAN WD repeat-containing protein 18 OS=Homo sapiens GN=WDR18 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.43 35 12 37 .. 82 106 .. 72 107 .. 0.81 2 ! 21.0 0.6 2.7e-05 0.0022 2 38 .] 112 149 .. 111 149 .. 0.93 3 ! 12.9 0.2 0.0094 0.76 4 37 .. 165 201 .. 163 202 .. 0.83 4 ! 35.9 0.3 5.3e-10 4.3e-08 5 38 .] 263 297 .. 259 297 .. 0.95 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.43 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +vt+l sp+g ++++G ++++W tr|K7EIR0|K7EIR0_HUMAN 82 PVTCLTASPNGLYVLAGV-AESIHLW 106 5**************886.7777777 PP == domain 2 score: 21.0 bits; conditional E-value: 2.7e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l +l+ H ++v++l+f d++ ++sG++D+ v +W+ tr|K7EIR0|K7EIR0_HUMAN 112 NLLVILSRHyQDVSCLQFTGDSSHFISGGKDCLVLVWS 149 67788999*99**************************5 PP == domain 3 score: 12.9 bits; conditional E-value: 0.0094 EEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw..lasGsdDgtvriW 37 ++++ H ++t+l g++ +a++s D+tv++W tr|K7EIR0|K7EIR0_HUMAN 165 RHVWSHHaLPITDLHCGFGGPLarVATSSLDQTVKLW 201 5778888777****98888888778999********* PP == domain 4 score: 35.9 bits; conditional E-value: 5.3e-10 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++GH + vt+l++s dg+ l+sGs D tvr+Wd tr|K7EIR0|K7EIR0_HUMAN 263 KVFKGHrNQVTCLSVSTDGSVLLSGSHDETVRLWD 297 689***999****************99*******9 PP >> sp|Q32P44-2|EMAL3_HUMAN Isoform 2 of Echinoderm microtubule-associated protein-like 3 OS=Homo sapiens GN=EML3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.2 7.1e-06 0.00058 4 38 .] 298 343 .. 295 343 .. 0.80 2 ? 4.7 0.2 3.8 3.1e+02 15 38 .] 410 433 .. 382 433 .. 0.73 3 ? 8.2 0.0 0.3 24 9 37 .. 512 541 .. 505 541 .. 0.87 4 ! 18.7 0.3 0.00014 0.011 7 38 .] 593 625 .. 589 625 .. 0.88 5 ? 10.1 0.0 0.073 6 16 37 .. 686 707 .. 673 708 .. 0.86 6 ! 18.4 0.7 0.00017 0.014 9 38 .] 724 754 .. 716 754 .. 0.86 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 7.1e-06 EEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 +r+++GH ++v++la++pdg +asG + + v+iWd sp|Q32P44-2|EMAL3_HUMAN 298 QRHYRGHtDCVRCLAVHPDGVRVASGqtaGVdkdgkplQPVVHIWD 343 89*****777**************9874432466778888888887 PP == domain 2 score: 4.7 bits; conditional E-value: 3.8 EEE.EETTSSEEEEEETTSEEEEEE CS WD40 15 sla.fspdgawlasGsdDgtvriWd 38 ++ +++d++ +++++ + +v++W+ sp|Q32P44-2|EMAL3_HUMAN 410 AVGfNPRDSSCIVTSG-KSHVHFWN 433 3434566777799999.*******8 PP == domain 3 score: 8.2 bits; conditional E-value: 0.3 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +s+ +l+ +dg+ l+ G++D+ + W sp|Q32P44-2|EMAL3_HUMAN 512 AHeGSIFALCLRRDGTVLSGGGRDRRLVQW 541 68888************97678****9999 PP == domain 4 score: 18.7 bits; conditional E-value: 0.00014 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH + ++l+++p+++ +++++ D+ + +Wd sp|Q32P44-2|EMAL3_HUMAN 593 IQGHtDELWGLCTHPSQNRFLTCGHDRQLCLWD 625 56**666************998877*******9 PP == domain 5 score: 10.1 bits; conditional E-value: 0.073 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 +++spdg +la Gs D+ ++i+ sp|Q32P44-2|EMAL3_HUMAN 686 VRYSPDGLYLAIGSHDNVIYIY 707 569**********99*****98 PP == domain 6 score: 18.4 bits; conditional E-value: 0.00017 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH s++t+l++s+dg++++s s D + Wd sp|Q32P44-2|EMAL3_HUMAN 724 GHsSFITHLDWSKDGNFIMSNSGDYEILYWD 754 9*777*************97555*****998 PP >> tr|H3BS99|H3BS99_HUMAN Zinc finger protein 106 (Fragment) OS=Homo sapiens GN=ZNF106 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 0.00079 0.064 5 38 .] 492 524 .. 489 524 .. 0.87 2 ! 20.8 0.1 3e-05 0.0024 1 38 [] 528 569 .. 528 569 .. 0.79 3 ? 9.6 0.0 0.1 8.4 4 36 .. 615 651 .. 612 653 .. 0.84 4 ? 11.2 0.1 0.033 2.7 3 35 .. 659 690 .. 657 691 .. 0.75 5 ? 9.4 0.0 0.12 10 1 37 [. 697 732 .. 697 733 .. 0.73 6 ? 7.0 0.0 0.71 57 4 34 .. 740 769 .. 738 770 .. 0.78 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 0.00079 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++GH v+++ + g++l ++s D+tvr+++ tr|H3BS99|H3BS99_HUMAN 492 GSFEGHqAAVNAI--QIFGNLLYTCSADKTVRVYN 524 6899**777**99..66888899**********97 PP == domain 2 score: 20.8 bits; conditional E-value: 3e-05 TEEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 ++c+++++GH s v++l +s +a l +Gs D+t+r ++ tr|H3BS99|H3BS99_HUMAN 528 RKCIGVFEGHtSKVNCLLvtqTSGKNAALYTGSSDHTIRCYN 569 58********777****87555555555778988*****987 PP == domain 3 score: 9.6 bits; conditional E-value: 0.1 EEEEESSSS..EEEEEEETTSSE..EEEEETTSEEEE CS WD40 4 lrtltGHss..vtslafspdgaw..lasGsdDgtvri 36 l +++ H++ v++la+ ++ga l+ Gs+D+t+ + tr|H3BS99|H3BS99_HUMAN 615 LEIFECHGPraVSCLATAQEGARklLVVGSYDCTISV 651 568999*6678*****999999998788*******87 PP == domain 4 score: 11.2 bits; conditional E-value: 0.033 EEEEEESS.SS......EEEEEEETTSSEEEEEETTSEEE CS WD40 3 clrtltGH.ss......vtslafspdgawlasGsdDgtvr 35 +lrtl+GH + v++l ++sGs D++v+ tr|H3BS99|H3BS99_HUMAN 659 LLRTLEGHsKTilcmkvVNDL--------VFSGSSDQSVH 690 689*****7775555544666........889*88*9985 PP == domain 5 score: 9.4 bits; conditional E-value: 0.12 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+++r+++GH++ vt + + g+ +++++ D+ vr++ tr|H3BS99|H3BS99_HUMAN 697 GELVRIYKGHNHaVTVV--NILGKVMVTACLDKFVRVY 732 6789******8886555..112444788888*****98 PP == domain 6 score: 7.0 bits; conditional E-value: 0.71 EEEEESSSS.EEEEEEETTSSEEEEEETTSEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtv 34 l+++ GH++ + ++ +++ + +G++Dg++ tr|H3BS99|H3BS99_HUMAN 740 LQVYGGHKDmIMCMTIHKSM--IYTGCYDGSI 769 7899***9999999554444..559*99**98 PP >> sp|Q9BV38|WDR18_HUMAN WD repeat-containing protein 18 OS=Homo sapiens GN=WDR18 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 0.0 0.46 37 12 37 .. 82 106 .. 72 107 .. 0.81 2 ! 20.9 0.6 2.9e-05 0.0024 2 38 .] 112 149 .. 111 149 .. 0.93 3 ? 12.8 0.2 0.01 0.82 4 37 .. 165 201 .. 163 202 .. 0.83 4 ! 35.8 0.3 5.6e-10 4.6e-08 5 38 .] 263 297 .. 259 297 .. 0.95 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.46 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +vt+l sp+g ++++G ++++W sp|Q9BV38|WDR18_HUMAN 82 PVTCLTASPNGLYVLAGV-AESIHLW 106 5**************886.7777777 PP == domain 2 score: 20.9 bits; conditional E-value: 2.9e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l +l+ H ++v++l+f d++ ++sG++D+ v +W+ sp|Q9BV38|WDR18_HUMAN 112 NLLVILSRHyQDVSCLQFTGDSSHFISGGKDCLVLVWS 149 67788999*99**************************5 PP == domain 3 score: 12.8 bits; conditional E-value: 0.01 EEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw..lasGsdDgtvriW 37 ++++ H ++t+l g++ +a++s D+tv++W sp|Q9BV38|WDR18_HUMAN 165 RHVWSHHaLPITDLHCGFGGPLarVATSSLDQTVKLW 201 5778888777****98888888778999********* PP == domain 4 score: 35.8 bits; conditional E-value: 5.6e-10 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++GH + vt+l++s dg+ l+sGs D tvr+Wd sp|Q9BV38|WDR18_HUMAN 263 KVFKGHrNQVTCLSVSTDGSVLLSGSHDETVRLWD 297 689***999****************99*******9 PP >> sp|Q9H2Y7|ZN106_HUMAN Zinc finger protein 106 OS=Homo sapiens GN=ZNF106 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 0.0019 0.16 5 38 .] 1525 1557 .. 1522 1557 .. 0.87 2 ! 19.6 0.1 7.5e-05 0.0061 1 38 [] 1561 1602 .. 1561 1602 .. 0.79 3 ? 8.4 0.0 0.26 21 4 36 .. 1648 1684 .. 1645 1686 .. 0.84 4 ? 10.0 0.1 0.082 6.7 3 35 .. 1692 1723 .. 1690 1724 .. 0.75 5 ? 8.1 0.0 0.31 25 1 37 [. 1730 1765 .. 1730 1766 .. 0.73 6 ? 5.8 0.0 1.7 1.4e+02 4 34 .. 1773 1802 .. 1771 1803 .. 0.78 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 0.0019 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++GH v+++ + g++l ++s D+tvr+++ sp|Q9H2Y7|ZN106_HUMAN 1525 GSFEGHqAAVNAI--QIFGNLLYTCSADKTVRVYN 1557 6899**777**99..66888899**********97 PP == domain 2 score: 19.6 bits; conditional E-value: 7.5e-05 TEEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 ++c+++++GH s v++l +s +a l +Gs D+t+r ++ sp|Q9H2Y7|ZN106_HUMAN 1561 RKCIGVFEGHtSKVNCLLvtqTSGKNAALYTGSSDHTIRCYN 1602 58********777****87555555555778988*****987 PP == domain 3 score: 8.4 bits; conditional E-value: 0.26 EEEEESSSS..EEEEEEETTSSE..EEEEETTSEEEE CS WD40 4 lrtltGHss..vtslafspdgaw..lasGsdDgtvri 36 l +++ H++ v++la+ ++ga l+ Gs+D+t+ + sp|Q9H2Y7|ZN106_HUMAN 1648 LEIFECHGPraVSCLATAQEGARklLVVGSYDCTISV 1684 568999*6678*****999999998788*******87 PP == domain 4 score: 10.0 bits; conditional E-value: 0.082 EEEEEESS.SS......EEEEEEETTSSEEEEEETTSEEE CS WD40 3 clrtltGH.ss......vtslafspdgawlasGsdDgtvr 35 +lrtl+GH + v++l ++sGs D++v+ sp|Q9H2Y7|ZN106_HUMAN 1692 LLRTLEGHsKTilcmkvVNDL--------VFSGSSDQSVH 1723 689*****7775555544666........889*88*9985 PP == domain 5 score: 8.1 bits; conditional E-value: 0.31 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+++r+++GH++ vt + + g+ +++++ D+ vr++ sp|Q9H2Y7|ZN106_HUMAN 1730 GELVRIYKGHNHaVTVV--NILGKVMVTACLDKFVRVY 1765 6789******8886555..112444788888*****98 PP == domain 6 score: 5.8 bits; conditional E-value: 1.7 EEEEESSSS.EEEEEEETTSSEEEEEETTSEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtv 34 l+++ GH++ + ++ +++ + +G++Dg++ sp|Q9H2Y7|ZN106_HUMAN 1773 LQVYGGHKDmIMCMTIHKSM--IYTGCYDGSI 1802 7899***9999999554444..559*99**98 PP >> tr|F5GXB6|F5GXB6_HUMAN WD repeat and SOCS box-containing protein 2 (Fragment) OS=Homo sapiens GN=WSB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.2 0.18 15 14 26 .. 32 44 .. 15 53 .. 0.82 2 ? 11.8 0.0 0.022 1.8 10 37 .. 117 140 .. 109 141 .. 0.73 3 ! 32.9 0.1 4.6e-09 3.8e-07 4 38 .] 148 184 .. 145 184 .. 0.87 4 ! 23.2 0.3 5.4e-06 0.00044 1 38 [] 189 227 .. 189 227 .. 0.91 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.18 EEEEEETTSSEEE CS WD40 14 tslafspdgawla 26 +s+afspdg+w+a tr|F5GXB6|F5GXB6_HUMAN 32 WSVAFSPDGSWFA 44 79*********85 PP == domain 2 score: 11.8 bits; conditional E-value: 0.022 SSS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 Hss....vtslafspdgawlasGsdDgtvriW 37 H + v++l la+G Dg ++iW tr|F5GXB6|F5GXB6_HUMAN 117 H-PqvpdVSCL-------VLATGLNDGQIKIW 140 4.233459999.......4478977******* PP == domain 3 score: 32.9 bits; conditional E-value: 4.6e-09 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 l l+GH++ v++l+f p+g+++ +s+s+D+t+riWd tr|F5GXB6|F5GXB6_HUMAN 148 LLNLSGHQDvVRDLSFTPSGSLIlVSASRDKTLRIWD 184 56799**8857***********62589*********9 PP == domain 4 score: 23.2 bits; conditional E-value: 5.4e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 g+++++l+GH ++v++++ spd ++l+s+ + ++v +W+ tr|F5GXB6|F5GXB6_HUMAN 189 GKQIQVLSGHlQWVYCCSISPDCSMLCSAaG-EKSVFLWS 227 67899*********************98735.*******5 PP >> tr|H0Y463|H0Y463_HUMAN Bromodomain and WD repeat-containing protein 1 (Fragment) OS=Homo sapiens GN=BRWD1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.1 5.6 4.5e+02 25 37 .. 2 13 .. 1 14 [. 0.83 2 ? 8.5 0.0 0.24 19 17 37 .. 43 63 .. 30 63 .. 0.87 3 ! 22.8 0.0 7.4e-06 0.0006 4 37 .. 73 107 .. 70 108 .. 0.89 4 ? 9.2 0.0 0.14 12 13 38 .] 141 166 .. 129 166 .. 0.90 5 ! 16.7 0.1 0.00063 0.051 1 38 [] 170 209 .. 170 209 .. 0.75 6 ? 10.5 0.2 0.057 4.6 7 32 .. 225 248 .. 214 255 .. 0.77 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 5.6 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 +++G Dgtv +W tr|H0Y463|H0Y463_HUMAN 2 VSTGA-DGTVCFW 13 46788.******* PP == domain 2 score: 8.5 bits; conditional E-value: 0.24 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 +fs g +la+Gs D+ +r++ tr|H0Y463|H0Y463_HUMAN 43 SFSVGGMFLATGSTDHVIRMY 63 5999999************86 PP == domain 3 score: 22.8 bits; conditional E-value: 7.4e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+ H + v s++f+ +g+ ++sGs+Dgt riW tr|H0Y463|H0Y463_HUMAN 73 IAELESHtDKVDSIQFCNNGDRFLSGSRDGTARIW 107 678999*555************************* PP == domain 4 score: 9.2 bits; conditional E-value: 0.14 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 vt +a++++ + ++++ D+ +++W+ tr|H0Y463|H0Y463_HUMAN 141 VTMIAWNQNDSIVVTAVNDHVLKVWN 166 77799**********988*******8 PP == domain 5 score: 16.7 bits; conditional E-value: 0.00063 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 gq+l+ l GH + v l ++p + l++G+ Dg++ iWd tr|H0Y463|H0Y463_HUMAN 170 GQLLHNLMGHaDEVFVLETHPFDSRimLSAGH-DGSIFIWD 209 689999****6669888866666663234566.*******9 PP == domain 6 score: 10.5 bits; conditional E-value: 0.057 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fs+dg+ +a ++ D tr|H0Y463|H0Y463_HUMAN 225 GQGHGAVFDCKFSQDGQHFA-CT-DS 248 469988************97.65.43 PP >> sp|Q676U5-3|A16L1_HUMAN Isoform 3 of Autophagy-related protein 16-1 OS=Homo sapiens GN=ATG16L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.7 0.0 4.7e-08 3.8e-06 5 37 .. 316 349 .. 313 350 .. 0.91 2 ! 13.7 0.0 0.0053 0.43 5 37 .. 360 393 .. 356 394 .. 0.87 3 ! 26.8 0.1 3.8e-07 3.1e-05 3 38 .] 400 436 .. 398 436 .. 0.91 Alignments for each domain: == domain 1 score: 29.7 bits; conditional E-value: 4.7e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++H + v++++fsp +++la+G++D+ v++W sp|Q676U5-3|A16L1_HUMAN 316 CVFDAHdGEVNAVQFSPGSRLLATGGMDRRVKLW 349 6799**666************************* PP == domain 2 score: 13.7 bits; conditional E-value: 0.0053 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l+G ++ts+ f++ g++l+++s D riW sp|Q676U5-3|A16L1_HUMAN 360 GSLSGSnAGITSIEFDSAGSYLLAASNDFASRIW 393 578888556**************9999******* PP == domain 3 score: 26.8 bits; conditional E-value: 3.8e-07 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + +tltGHs+ v s +f d+a ++sGs D+t+++Wd sp|Q676U5-3|A16L1_HUMAN 400 LRHTLTGHSGkVLSAKFLLDNARIVSGSHDRTLKLWD 436 5699****556****************99*******9 PP >> tr|H0Y4A7|H0Y4A7_HUMAN Bromodomain and WD repeat-containing protein 1 (Fragment) OS=Homo sapiens GN=BRWD1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.1 2.1 1.7e+02 25 37 .. 2 13 .. 1 14 [. 0.83 2 ? 10.0 0.0 0.078 6.3 17 37 .. 43 63 .. 29 63 .. 0.87 3 ! 24.4 0.0 2.3e-06 0.00019 4 37 .. 73 107 .. 70 108 .. 0.89 4 ? 10.8 0.0 0.046 3.7 13 38 .] 141 166 .. 127 166 .. 0.90 5 ! 18.3 0.1 0.00019 0.015 1 38 [] 170 209 .. 170 209 .. 0.75 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 2.1 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 +++G Dgtv +W tr|H0Y4A7|H0Y4A7_HUMAN 2 VSTGA-DGTVCFW 13 46788.******* PP == domain 2 score: 10.0 bits; conditional E-value: 0.078 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 +fs g +la+Gs D+ +r++ tr|H0Y4A7|H0Y4A7_HUMAN 43 SFSVGGMFLATGSTDHVIRMY 63 5999999************86 PP == domain 3 score: 24.4 bits; conditional E-value: 2.3e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l+ H + v s++f+ +g+ ++sGs+Dgt riW tr|H0Y4A7|H0Y4A7_HUMAN 73 IAELESHtDKVDSIQFCNNGDRFLSGSRDGTARIW 107 678999*555************************* PP == domain 4 score: 10.8 bits; conditional E-value: 0.046 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 vt +a++++ + ++++ D+ +++W+ tr|H0Y4A7|H0Y4A7_HUMAN 141 VTMIAWNQNDSIVVTAVNDHVLKVWN 166 77799**********988*******8 PP == domain 5 score: 18.3 bits; conditional E-value: 0.00019 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 gq+l+ l GH + v l ++p + l++G+ Dg++ iWd tr|H0Y4A7|H0Y4A7_HUMAN 170 GQLLHNLMGHaDEVFVLETHPFDSRimLSAGH-DGSIFIWD 209 68999*****6669888866666663234566.*******9 PP >> tr|B4DFS1|B4DFS1_HUMAN WD repeat and SOCS box-containing protein 2 OS=Homo sapiens GN=WSB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.1 0.1 1.9e-09 1.5e-07 3 38 .] 6 42 .. 4 42 .. 0.94 2 ! 21.8 0.1 1.5e-05 0.0012 10 37 .. 67 95 .. 51 95 .. 0.94 3 ! 15.4 0.0 0.0015 0.12 15 37 .. 113 135 .. 105 136 .. 0.92 Alignments for each domain: == domain 1 score: 34.1 bits; conditional E-value: 1.9e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r+l+GH ssv s++fspd+a+l+++s+D +v +Wd tr|B4DFS1|B4DFS1_HUMAN 6 LIRKLEGHqSSVVSCDFSPDSALLVTASYDTNVIMWD 42 6899****99999***********************9 PP == domain 2 score: 21.8 bits; conditional E-value: 1.5e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ss +s++fsp+g +la+ dD+ +riW tr|B4DFS1|B4DFS1_HUMAN 67 HiSSLRSVCFSPEGLYLATVADDRLLRIW 95 88899*************9999******* PP == domain 3 score: 15.4 bits; conditional E-value: 0.0015 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ f p+g +a+G++Dg+v +W tr|B4DFS1|B4DFS1_HUMAN 113 CCTFFPHGGVIATGTRDGHVQFW 135 788******************** PP >> tr|E9PE29|E9PE29_HUMAN Zinc finger protein 106 OS=Homo sapiens GN=ZNF106 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 0.0011 0.087 5 38 .] 753 785 .. 750 785 .. 0.87 2 ! 20.4 0.1 4.1e-05 0.0033 1 38 [] 789 830 .. 789 830 .. 0.79 3 ? 9.2 0.0 0.14 12 4 36 .. 876 912 .. 873 914 .. 0.84 4 ? 10.8 0.1 0.046 3.7 3 35 .. 920 951 .. 918 952 .. 0.75 5 ? 9.0 0.0 0.17 14 1 37 [. 958 993 .. 958 994 .. 0.73 6 ? 6.6 0.0 0.97 78 4 34 .. 1001 1030 .. 999 1031 .. 0.78 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0011 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++GH v+++ + g++l ++s D+tvr+++ tr|E9PE29|E9PE29_HUMAN 753 GSFEGHqAAVNAI--QIFGNLLYTCSADKTVRVYN 785 6899**777**99..66888899**********97 PP == domain 2 score: 20.4 bits; conditional E-value: 4.1e-05 TEEEEEEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 ++c+++++GH s v++l +s +a l +Gs D+t+r ++ tr|E9PE29|E9PE29_HUMAN 789 RKCIGVFEGHtSKVNCLLvtqTSGKNAALYTGSSDHTIRCYN 830 58********777****87555555555778988*****987 PP == domain 3 score: 9.2 bits; conditional E-value: 0.14 EEEEESSSS..EEEEEEETTSSE..EEEEETTSEEEE CS WD40 4 lrtltGHss..vtslafspdgaw..lasGsdDgtvri 36 l +++ H++ v++la+ ++ga l+ Gs+D+t+ + tr|E9PE29|E9PE29_HUMAN 876 LEIFECHGPraVSCLATAQEGARklLVVGSYDCTISV 912 568999*6678*****999999998788*******87 PP == domain 4 score: 10.8 bits; conditional E-value: 0.046 EEEEEESS.SS......EEEEEEETTSSEEEEEETTSEEE CS WD40 3 clrtltGH.ss......vtslafspdgawlasGsdDgtvr 35 +lrtl+GH + v++l ++sGs D++v+ tr|E9PE29|E9PE29_HUMAN 920 LLRTLEGHsKTilcmkvVNDL--------VFSGSSDQSVH 951 689*****7775555544666........889*88*9985 PP == domain 5 score: 9.0 bits; conditional E-value: 0.17 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+++r+++GH++ vt + + g+ +++++ D+ vr++ tr|E9PE29|E9PE29_HUMAN 958 GELVRIYKGHNHaVTVV--NILGKVMVTACLDKFVRVY 993 6789******8886555..112444788888*****98 PP == domain 6 score: 6.6 bits; conditional E-value: 0.97 EEEEESSSS.EEEEEEETTSSEEEEEETTSEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtv 34 l+++ GH++ + ++ +++ + +G++Dg++ tr|E9PE29|E9PE29_HUMAN 1001 LQVYGGHKDmIMCMTIHKSM--IYTGCYDGSI 1030 7899***9999999554444..559*99**98 PP >> tr|F8VX21|F8VX21_HUMAN POC1 centriolar protein homolog B OS=Homo sapiens GN=POC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.4 0.0 1.4e-08 1.1e-06 6 38 .] 13 46 .. 6 46 .. 0.90 2 ! 39.6 0.0 3.6e-11 2.9e-09 7 37 .. 56 87 .. 52 87 .. 0.92 Alignments for each domain: == domain 1 score: 31.4 bits; conditional E-value: 1.4e-08 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++GH +tsl+ sp+g+ la++s+D +++W+ tr|F8VX21|F8VX21_HUMAN 13 YFKGHkAAITSLDLSPNGKQLATASWDTFLMLWN 46 589**666*************************8 PP == domain 2 score: 39.6 bits; conditional E-value: 3.6e-11 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 + GH++ vts++fsp+g++las+s+D+tvr+W tr|F8VX21|F8VX21_HUMAN 56 YVGHKDvVTSVQFSPHGNLLASASRDRTVRLW 87 67**9966************************ PP >> sp|Q8N157-2|AHI1_HUMAN Isoform 2 of Jouberin OS=Homo sapiens GN=AHI1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.87 70 14 32 .. 613 633 .. 596 634 .. 0.77 2 ! 28.1 0.3 1.6e-07 1.3e-05 2 38 .] 645 682 .. 644 682 .. 0.90 3 ? 10.4 0.0 0.058 4.7 13 38 .] 700 726 .. 688 726 .. 0.65 4 ! 13.5 0.6 0.0061 0.49 4 38 .] 737 772 .. 735 772 .. 0.90 5 ? 12.6 0.0 0.012 1 19 38 .] 852 871 .. 835 871 .. 0.89 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.87 EEEEEETTSSEEEEE..ETTS CS WD40 14 tslafspdgawlasG..sdDg 32 +l+fs++g+ la++ s+Dg sp|Q8N157-2|AHI1_HUMAN 613 FCLDFSHNGRILAAAcaSRDG 633 69*********9854247898 PP == domain 2 score: 28.1 bits; conditional E-value: 1.6e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r+l GH + +++l++s+d ++++++s Dgt riW+ sp|Q8N157-2|AHI1_HUMAN 645 RFMRELCGHlNIIYDLSWSKDDHYILTSSSDGTARIWK 682 5689999**999************998877*******6 PP == domain 3 score: 10.4 bits; conditional E-value: 0.058 EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw.lasGsdDgtvriWd 38 v+ +f+p + +++G++D +riW+ sp|Q8N157-2|AHI1_HUMAN 700 VYTAKFHPAVRElVVTGCYDSMIRIWK 726 444444444444178***********6 PP == domain 4 score: 13.5 bits; conditional E-value: 0.0061 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r ++ H s+++sl+f+ +g+ + sG+ g + +W+ sp|Q8N157-2|AHI1_HUMAN 737 VRQFDVHkSFINSLCFDTEGHHMYSGDCTGVIVVWN 772 688999*777****************77*******8 PP == domain 5 score: 12.6 bits; conditional E-value: 0.012 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 p g++l++Gs+Dg v++W+ sp|Q8N157-2|AHI1_HUMAN 852 TPCGTFLFAGSEDGIVYVWN 871 6999***************8 PP >> sp|Q5XX13-4|FBW10_HUMAN Isoform 4 of F-box/WD repeat-containing protein 10 OS=Homo sapiens GN=FBXW10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 0.0017 0.14 6 38 .] 448 481 .. 445 481 .. 0.95 2 ! 25.7 0.6 8.9e-07 7.2e-05 1 38 [] 485 521 .. 485 521 .. 0.88 3 ? 7.3 0.1 0.59 48 1 37 [. 525 559 .. 525 560 .. 0.89 4 ! 14.3 0.2 0.0034 0.28 2 37 .. 565 599 .. 564 600 .. 0.83 5 ? 7.8 0.0 0.41 33 2 38 .] 607 641 .. 606 641 .. 0.72 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 0.0017 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH +sv++l + + ++l+sGs+D ++r Wd sp|Q5XX13-4|FBW10_HUMAN 448 EFRGHaGSVRALFLCEEENFLLSGSYDLSIRYWD 481 599**999*************************9 PP == domain 2 score: 25.7 bits; conditional E-value: 8.9e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g c+r++ GH + +t++ ++ l+sG++D+ v++Wd sp|Q5XX13-4|FBW10_HUMAN 485 GVCTRIFGGHqGTITCM------DLcknrLVSGGRDCQVKVWD 521 579*******777****......66666699***********9 PP == domain 3 score: 7.3 bits; conditional E-value: 0.59 TEEEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssv..tslafspdgawlasGsdDgtvriW 37 g+cl+t++ H +++ t + + ++++s+++ g v++W sp|Q5XX13-4|FBW10_HUMAN 525 GKCLKTFR-HkDPIlaTRI----NDTYIVSSCERGLVKVW 559 79*****9.9666778999....9*****9999******* PP == domain 4 score: 14.3 bits; conditional E-value: 0.0034 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 q+++tl+GH + v +l f +w l+sGs Dg v+ W sp|Q5XX13-4|FBW10_HUMAN 565 QLVKTLSGHeGAVKCLFF---DQWhLLSGSTDGLVMAW 599 789******888****54...477557********999 PP == domain 5 score: 7.8 bits; conditional E-value: 0.41 EEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +cl ++ H + v ++ ++ ++s++ Dg++ri++ sp|Q5XX13-4|FBW10_HUMAN 607 RCLMAFK-HpKEVLDV------SLlflrVISACADGKIRIYN 641 6777786.87888888......664555456666******98 PP >> sp|Q5XX13|FBW10_HUMAN F-box/WD repeat-containing protein 10 OS=Homo sapiens GN=FBXW10 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 0.0017 0.14 6 38 .] 448 481 .. 445 481 .. 0.95 2 ! 25.7 0.6 8.9e-07 7.2e-05 1 38 [] 485 521 .. 485 521 .. 0.88 3 ? 7.3 0.1 0.59 48 1 37 [. 525 559 .. 525 560 .. 0.89 4 ! 14.3 0.2 0.0034 0.28 2 37 .. 565 599 .. 564 600 .. 0.83 5 ? 7.8 0.0 0.41 33 2 38 .] 607 641 .. 606 641 .. 0.72 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 0.0017 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH +sv++l + + ++l+sGs+D ++r Wd sp|Q5XX13|FBW10_HUMAN 448 EFRGHaGSVRALFLCEEENFLLSGSYDLSIRYWD 481 599**999*************************9 PP == domain 2 score: 25.7 bits; conditional E-value: 8.9e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g c+r++ GH + +t++ ++ l+sG++D+ v++Wd sp|Q5XX13|FBW10_HUMAN 485 GVCTRIFGGHqGTITCM------DLcknrLVSGGRDCQVKVWD 521 579*******777****......66666699***********9 PP == domain 3 score: 7.3 bits; conditional E-value: 0.59 TEEEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssv..tslafspdgawlasGsdDgtvriW 37 g+cl+t++ H +++ t + + ++++s+++ g v++W sp|Q5XX13|FBW10_HUMAN 525 GKCLKTFR-HkDPIlaTRI----NDTYIVSSCERGLVKVW 559 79*****9.9666778999....9*****9999******* PP == domain 4 score: 14.3 bits; conditional E-value: 0.0034 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 q+++tl+GH + v +l f +w l+sGs Dg v+ W sp|Q5XX13|FBW10_HUMAN 565 QLVKTLSGHeGAVKCLFF---DQWhLLSGSTDGLVMAW 599 789******888****54...477557********999 PP == domain 5 score: 7.8 bits; conditional E-value: 0.41 EEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +cl ++ H + v ++ ++ ++s++ Dg++ri++ sp|Q5XX13|FBW10_HUMAN 607 RCLMAFK-HpKEVLDV------SLlflrVISACADGKIRIYN 641 6777786.87888888......664555456666******98 PP >> sp|Q5XX13-2|FBW10_HUMAN Isoform 2 of F-box/WD repeat-containing protein 10 OS=Homo sapiens GN=FBXW10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 0.0017 0.14 6 38 .] 477 510 .. 474 510 .. 0.95 2 ! 25.7 0.6 9e-07 7.3e-05 1 38 [] 514 550 .. 514 550 .. 0.88 3 ? 7.2 0.1 0.59 48 1 37 [. 554 588 .. 554 589 .. 0.89 4 ! 14.3 0.2 0.0035 0.28 2 37 .. 594 628 .. 593 629 .. 0.83 5 ? 7.8 0.0 0.41 33 2 38 .] 636 670 .. 635 670 .. 0.72 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 0.0017 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH +sv++l + + ++l+sGs+D ++r Wd sp|Q5XX13-2|FBW10_HUMAN 477 EFRGHaGSVRALFLCEEENFLLSGSYDLSIRYWD 510 599**999*************************9 PP == domain 2 score: 25.7 bits; conditional E-value: 9e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g c+r++ GH + +t++ ++ l+sG++D+ v++Wd sp|Q5XX13-2|FBW10_HUMAN 514 GVCTRIFGGHqGTITCM------DLcknrLVSGGRDCQVKVWD 550 579*******777****......66666699***********9 PP == domain 3 score: 7.2 bits; conditional E-value: 0.59 TEEEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssv..tslafspdgawlasGsdDgtvriW 37 g+cl+t++ H +++ t + + ++++s+++ g v++W sp|Q5XX13-2|FBW10_HUMAN 554 GKCLKTFR-HkDPIlaTRI----NDTYIVSSCERGLVKVW 588 79*****9.9666778999....9*****9999******* PP == domain 4 score: 14.3 bits; conditional E-value: 0.0035 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 q+++tl+GH + v +l f +w l+sGs Dg v+ W sp|Q5XX13-2|FBW10_HUMAN 594 QLVKTLSGHeGAVKCLFF---DQWhLLSGSTDGLVMAW 628 789******888****54...477557********999 PP == domain 5 score: 7.8 bits; conditional E-value: 0.41 EEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +cl ++ H + v ++ ++ ++s++ Dg++ri++ sp|Q5XX13-2|FBW10_HUMAN 636 RCLMAFK-HpKEVLDV------SLlflrVISACADGKIRIYN 670 6777786.87888888......664555456666******98 PP >> sp|A6NGE4|DC8L1_HUMAN DDB1- and CUL4-associated factor 8-like protein 1 OS=Homo sapiens GN=DCAF8L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.1 0.0077 0.62 4 38 .] 189 224 .. 186 224 .. 0.90 2 ? 6.6 0.0 0.96 78 8 36 .. 236 267 .. 228 267 .. 0.76 3 ? 3.6 0.0 8.3 6.8e+02 25 38 .] 350 363 .. 331 363 .. 0.76 4 ? 7.7 0.0 0.42 34 12 38 .] 388 418 .. 374 418 .. 0.73 5 ! 16.7 0.0 0.00062 0.05 2 37 .. 426 465 .. 425 466 .. 0.87 6 ! 17.4 0.0 0.00036 0.029 9 37 .. 478 508 .. 470 509 .. 0.84 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 0.0077 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ l H +sv+ + f++ g+ las++dD v +Wd sp|A6NGE4|DC8L1_HUMAN 189 QYLLGSHaGSVSTIHFNQRGTRLASSGDDLRVIVWD 224 5567889888***************99********9 PP == domain 2 score: 6.6 bits; conditional E-value: 0.96 ESSSSEEEEE.....EETTSSEEEEEETTSEEEE CS WD40 8 tGHssvtsla.....fspdgawlasGsdDgtvri 36 +GH +++ ++ ++ d+++ ++G+ Dg vr+ sp|A6NGE4|DC8L1_HUMAN 236 SGH-DINVIQakffpNCGDSTLAMCGH-DGQVRV 267 499.88766678877888888888999.****97 PP == domain 3 score: 3.6 bits; conditional E-value: 8.3 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 +a G+ D+ vri+d sp|A6NGE4|DC8L1_HUMAN 350 FAVGGHDQFVRIYD 363 466877******98 PP == domain 4 score: 7.7 bits; conditional E-value: 0.42 S....EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s....vtslafspdgawlasGsdDgtvriWd 38 + +t++ +s+dg+ l+++ D +++++ sp|A6NGE4|DC8L1_HUMAN 388 DfptnITCVVYSHDGTELLASYNDEDIYLFN 418 25667*************9998898888876 PP == domain 5 score: 16.7 bits; conditional E-value: 0.00062 EEEEEEESS..SS.EEEEE.EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH..ss.vtsla.fspdgawlasGsdDgtvriW 37 q ++ ++GH ++ + ++ + p + +++sGsd g+v +W sp|A6NGE4|DC8L1_HUMAN 426 QYVKRYKGHrnNDtIKCVNfYGPRSEFVVSGSDCGHVFFW 465 56788****95449****999999999************* PP == domain 6 score: 17.4 bits; conditional E-value: 0.00036 SS.SS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ss.vtslafspdgawlasGsdDgtvriW 37 G ++ v++l +p+ + la+++ D++vriW sp|A6NGE4|DC8L1_HUMAN 478 GDrGDiVNCLEPHPYLPVLATSGLDQHVRIW 508 5544557*************9999******* PP >> tr|B4DPV6|B4DPV6_HUMAN WD repeat and SOCS box-containing protein 2 OS=Homo sapiens GN=WSB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.9 0.1 2.2e-09 1.8e-07 3 38 .] 21 57 .. 19 57 .. 0.94 2 ! 21.7 0.1 1.7e-05 0.0013 10 37 .. 82 110 .. 66 110 .. 0.94 3 ! 15.3 0.0 0.0017 0.14 15 37 .. 128 150 .. 120 151 .. 0.92 Alignments for each domain: == domain 1 score: 33.9 bits; conditional E-value: 2.2e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r+l+GH ssv s++fspd+a+l+++s+D +v +Wd tr|B4DPV6|B4DPV6_HUMAN 21 LIRKLEGHqSSVVSCDFSPDSALLVTASYDTNVIMWD 57 6899****99999***********************9 PP == domain 2 score: 21.7 bits; conditional E-value: 1.7e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ss +s++fsp+g +la+ dD+ +riW tr|B4DPV6|B4DPV6_HUMAN 82 HiSSLRSVCFSPEGLYLATVADDRLLRIW 110 88899*************9999******* PP == domain 3 score: 15.3 bits; conditional E-value: 0.0017 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ f p+g +a+G++Dg+v +W tr|B4DPV6|B4DPV6_HUMAN 128 CCTFFPHGGVIATGTRDGHVQFW 150 788******************** PP >> tr|B3KPW7|B3KPW7_HUMAN DNA excision repair protein ERCC-8 OS=Homo sapiens GN=ERCC8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.4 0.0081 0.66 9 38 .] 39 70 .. 27 70 .. 0.71 2 ! 30.7 0.1 2.4e-08 1.9e-06 1 38 [] 118 157 .. 118 157 .. 0.92 3 ! 17.9 0.1 0.00026 0.021 8 38 .] 184 215 .. 163 215 .. 0.87 4 ! 14.7 0.0 0.0027 0.22 2 37 .. 267 303 .. 266 304 .. 0.87 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.0081 SS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawla.sGsdDgtvriWd 38 H sv +++ p+ + ++ s+s D+t+++Wd tr|B3KPW7|B3KPW7_HUMAN 39 VHrYSVETVQWYPHDTGMFtSSSFDKTLKVWD 70 454458888766666665516678*******9 PP == domain 2 score: 30.7 bits; conditional E-value: 2.4e-08 TEEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 g+c ++l GH + + ++++sp +++ a++s D v++Wd tr|B3KPW7|B3KPW7_HUMAN 118 GSCSHILQGHrQEILAVSWSPRYDYIlATASADSRVKLWD 157 68********999************6268899*******9 PP == domain 3 score: 17.9 bits; conditional E-value: 0.00026 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 t+H++ v++l+f +dg l++ + D+ r+W+ tr|B3KPW7|B3KPW7_HUMAN 184 TAHNGkVNGLCFTSDGLHLLTVGTDNRMRLWN 215 689556************997666*******8 PP == domain 4 score: 14.7 bits; conditional E-value: 0.0027 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++ l+GH + v ++ f+++ + l sGs+D+++ W tr|B3KPW7|B3KPW7_HUMAN 267 EQITMLKGHyKTVDCCVFQSNFQELYSGSRDCNILAW 303 667889*******77779999999*********9877 PP >> tr|C9JC24|C9JC24_HUMAN WD repeat-containing protein 48 (Fragment) OS=Homo sapiens GN=WDR48 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 1.2 0.00011 0.0087 10 38 .] 4 33 .. 1 33 [. 0.80 2 ! 23.8 0.0 3.5e-06 0.00028 3 38 .] 39 75 .. 37 75 .. 0.93 3 ! 18.0 0.0 0.00024 0.02 4 38 .] 91 126 .. 86 126 .. 0.91 4 ? 11.3 0.0 0.031 2.5 3 32 .. 132 162 .] 130 162 .] 0.88 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 0.00011 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H ++v+++ + +g+ l+s+s D tv++W+ tr|C9JC24|C9JC24_HUMAN 4 HtDWVNDIVLCCNGKTLISASSDTTVKVWN 33 655577777777*****99988*******8 PP == domain 2 score: 23.8 bits; conditional E-value: 3.5e-06 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 c+ tl++H++ v +la+ +d+ ++as++ D+ + +Wd tr|C9JC24|C9JC24_HUMAN 39 CMSTLRTHKDyVKALAYAKDKELVASAGLDRQIFLWD 75 999*****666**************9999*******9 PP == domain 3 score: 18.0 bits; conditional E-value: 0.00024 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +l+G +s++sla ++ g+ ++sGs + +r+Wd tr|C9JC24|C9JC24_HUMAN 91 TSSLSGNkDSIYSLAMNQLGTIIVSGSTEKVLRVWD 126 56799**777*************************9 PP == domain 4 score: 11.3 bits; conditional E-value: 0.031 EEEEEESS.SSEEEEEEETTSSEEEEEETTS CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDg 32 +l +l+GH ++v +l ++dg+ +sGs Dg tr|C9JC24|C9JC24_HUMAN 132 KLMKLKGHtDNVKALLLNRDGTQCLSGSSDG 162 57889***766************99**8897 PP >> sp|Q8NI36|WDR36_HUMAN WD repeat-containing protein 36 OS=Homo sapiens GN=WDR36 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.3 0.3 0.0073 0.59 3 37 .. 154 187 .. 152 188 .. 0.89 2 ? 5.3 0.0 2.4 1.9e+02 9 37 .. 331 360 .. 323 360 .. 0.83 3 ? 3.9 0.0 6.9 5.6e+02 9 34 .. 377 404 .. 369 407 .. 0.80 4 ? 6.4 0.1 1.1 88 9 38 .] 537 567 .. 528 567 .. 0.86 5 ! 36.5 0.0 3.3e-10 2.7e-08 2 38 .] 613 650 .. 612 650 .. 0.93 6 ? 3.5 0.1 8.9 7.2e+02 16 32 .. 669 685 .. 663 686 .. 0.88 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 0.0073 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++t++GH ++ l +p g+ ++s + Dg + iW sp|Q8NI36|WDR36_HUMAN 154 IVHTFKGHkAEIHFL--QPFGDHIISVDTDGILIIW 187 69******655**99..********9988******* PP == domain 2 score: 5.3 bits; conditional E-value: 2.4 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H + + +l f + ++l++ + D+ +riW sp|Q8NI36|WDR36_HUMAN 331 AHsTAIAGLTFLHREPLLVTNGADNALRIW 360 79555999999999999998666******* PP == domain 3 score: 3.9 bits; conditional E-value: 6.9 SS.SSEEEEE.EETTSSEEEEEETTSEE CS WD40 9 GH.ssvtsla.fspdgawlasGsdDgtv 34 GH + t ++ + ++g+ ++s+s Dgt+ sp|Q8NI36|WDR36_HUMAN 377 GHsAPLTNIRyYGQNGQQILSASQDGTL 404 9966688888888899999*******97 PP == domain 4 score: 6.4 bits; conditional E-value: 1.1 SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +H +sv+++a++ +++ +++Gs g +++W+ sp|Q8NI36|WDR36_HUMAN 537 AHkGSVRGVAVDGLNQLtVTTGS-EGLLKFWN 567 79777****99999999788999.*******8 PP == domain 5 score: 36.5 bits; conditional E-value: 3.3e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r+++GH + ++++afspdg+wl+s+ +D+++r Wd sp|Q8NI36|WDR36_HUMAN 613 KIVREFSGHqGQINDMAFSPDGRWLISAAMDCSIRTWD 650 6799*****777**************9999*******9 PP == domain 6 score: 3.5 bits; conditional E-value: 8.9 EEEETTSSEEEEEETTS CS WD40 16 lafspdgawlasGsdDg 32 ++ sp g++la+++ D+ sp|Q8NI36|WDR36_HUMAN 669 VSMSPTGDFLATSHVDH 685 667**********9997 PP >> sp|Q9BQ67|GRWD1_HUMAN Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens GN=GRWD1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 8.2 6.7e+02 2 37 .. 205 242 .. 204 243 .. 0.64 2 ! 26.0 0.1 6.8e-07 5.5e-05 4 38 .] 254 290 .. 252 290 .. 0.89 3 ! 24.9 0.1 1.6e-06 0.00013 6 38 .] 303 336 .. 298 336 .. 0.90 4 ! 19.4 0.1 8.8e-05 0.0071 1 38 [] 343 382 .. 343 382 .. 0.83 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.2 EEEEEEESS..SSEEEEEEETTSSE.......EEEEETTSEEEEE CS WD40 2 qclrtltGH..ssvtslafspdgaw.......lasGsdDgtvriW 37 +++ ++ GH + +l +w l++G+ +++++W sp|Q9BQ67|GRWD1_HUMAN 205 KPIFSFAGHmgEGF-AL------DWsprvtgrLLTGDCQKNIHLW 242 57778888874333.55......333333335779*77******* PP == domain 2 score: 26.0 bits; conditional E-value: 6.8e-07 EEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 +r + GH sv +l++sp + + as+s D ++riWd sp|Q9BQ67|GRWD1_HUMAN 254 QRPFVGHtRSVEDLQWSPTENTVfASCSADASIRIWD 290 67899**777************8468999*******9 PP == domain 3 score: 24.9 bits; conditional E-value: 1.6e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t t+H ++v+ +++s+ ++l+sG+dDg ++iWd sp|Q9BQ67|GRWD1_HUMAN 303 TATAHdGDVNVISWSRREPFLLSGGDDGALKIWD 336 4579*888*************************9 PP == domain 4 score: 19.4 bits; conditional E-value: 8.8e-05 TEEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 g+++ t++ H +vts+ ++p + ++ +++ D+ + Wd sp|Q9BQ67|GRWD1_HUMAN 343 GSPVATFKQHvAPVTSVEWHPQDSGVFaASGADHQITQWD 382 57999*****999****999998887423455*******9 PP >> tr|C9J8B4|C9J8B4_HUMAN pre-mRNA 3' end-processing protein WDR33 (Fragment) OS=Homo sapiens GN=WDR33 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 2.8 2.3e+02 13 38 .] 44 69 .. 30 69 .. 0.81 2 ! 15.3 0.1 0.0017 0.13 5 37 .. 77 110 .. 73 111 .. 0.90 3 ! 31.9 0.0 9.7e-09 7.8e-07 2 38 .] 115 152 .. 114 152 .. 0.92 4 ! 22.7 0.2 7.9e-06 0.00064 5 32 .. 160 188 .. 156 189 .. 0.91 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 2.8 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v +++ p+g+ l++G g +W+ tr|C9J8B4|C9J8B4_HUMAN 44 VFVVRWTPEGRRLVTGASSGEFTLWN 69 55578***********5599999997 PP == domain 2 score: 15.3 bits; conditional E-value: 0.0017 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l +H s+v+++ +s++ w+++++ g v+ W tr|C9J8B4|C9J8B4_HUMAN 77 TILQAHdSPVRAMTWSHNDMWMLTADHGGYVKYW 110 5789**888****************88*****99 PP == domain 3 score: 31.9 bits; conditional E-value: 9.7e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ + +H ++ +fsp + +a++sdDgtvriWd tr|C9J8B4|C9J8B4_HUMAN 115 NNVKMFQAHkEAIREASFSPTDNKFATCSDDGTVRIWD 152 68899****655*************************9 PP == domain 4 score: 22.7 bits; conditional E-value: 7.9e-06 EEEESS.SSEEEEEEETTSSEEEEEETTS CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDg 32 r+l+GH +v +++++p + +++sGs+D tr|C9J8B4|C9J8B4_HUMAN 160 RILRGHgADVKCVDWHPTKGLVVSGSKDS 188 89****888*****************995 PP >> tr|H0Y8R5|H0Y8R5_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 1.1 1.7e-06 0.00014 9 38 .] 4 36 .. 3 36 .. 0.91 2 ! 25.8 0.2 8.3e-07 6.7e-05 7 38 .] 46 78 .. 40 78 .. 0.86 3 ! 22.2 0.4 1.1e-05 0.0009 1 37 [. 82 117 .. 82 132 .. 0.78 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 1.7e-06 SS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGsdDgtvriWd 38 H +v++++fsp+++ ++s+++D+ v++W+ tr|H0Y8R5|H0Y8R5_HUMAN 4 SHsEWVSCVRFSPNSSNpiIVSCGWDKLVKVWN 36 58566*************989***********8 PP == domain 2 score: 25.8 bits; conditional E-value: 8.3e-07 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + + + +spdg++ asG++Dg ++Wd tr|H0Y8R5|H0Y8R5_HUMAN 46 HIGHtGYLNTVTVSPDGSLCASGGKDGQAMLWD 78 3499666*************************9 PP == domain 3 score: 22.2 bits; conditional E-value: 1.1e-05 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g++l+tl+G + +++l+fsp+ wl++++ ++++iW tr|H0Y8R5|H0Y8R5_HUMAN 82 GKHLYTLDGG-DiINALCFSPNRYWLCAAT-GPSIKIW 117 5778889887.448***********98766.7777777 PP >> sp|Q8IWB7|WDFY1_HUMAN WD repeat and FYVE domain-containing protein 1 OS=Homo sapiens GN=WDFY1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.9 0.0 0.0023 0.18 4 37 .. 17 51 .. 15 51 .. 0.83 2 ? 11.0 0.0 0.04 3.2 3 34 .. 106 138 .. 104 139 .. 0.84 3 ! 24.7 0.6 1.8e-06 0.00014 4 38 .] 192 227 .. 189 227 .. 0.92 4 ? 12.5 0.1 0.013 1.1 7 38 .] 238 270 .. 230 270 .. 0.82 5 ? 12.6 0.1 0.012 0.99 13 38 .] 376 394 .. 357 394 .. 0.65 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 0.0023 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l +++GH + vt+ p + ++++s+D+t+r+W sp|Q8IWB7|WDFY1_HUMAN 17 LSKIEGHqDAVTAALLIPKEDGVITASEDRTIRVW 51 56679**666*99977777777899********** PP == domain 2 score: 11.0 bits; conditional E-value: 0.04 EEEEEESS.SSEEEEEEETTSSEEE.EEETTSEE CS WD40 3 clrtltGH.ssvtslafspdgawla.sGsdDgtv 34 ++t+ +H + v+++ fs w++ +G+ D+ v sp|Q8IWB7|WDFY1_HUMAN 106 FIKTYPAHqNRVSAIIFSLATEWVIsTGH-DKCV 138 6899****988************983566.9987 PP == domain 3 score: 24.7 bits; conditional E-value: 1.8e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++tl+GH +sv +l ++p +++l+sG D+++ +Wd sp|Q8IWB7|WDFY1_HUMAN 192 ITTLKGHeGSVACLWWDPIQRLLFSGASDNSIIMWD 227 789****999****************66*******9 PP == domain 4 score: 12.5 bits; conditional E-value: 0.013 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH + v sl++ + + l+s+s Dg + +W+ sp|Q8IWB7|WDFY1_HUMAN 238 LQGHhDKVQSLCYLQLTRQLVSCSSDGGIAVWN 270 5799666****98888888999988*******8 PP == domain 5 score: 12.6 bits; conditional E-value: 0.012 E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 v.tslafspdgawlasGsdDgtvriWd 38 + ++l +++++ D+ v+iWd sp|Q8IWB7|WDFY1_HUMAN 376 IaRGL--------MVTCGTDRIVKIWD 394 44555........778877*******9 PP >> sp|Q04725-2|TLE2_HUMAN Isoform 2 of Transducin-like enhancer protein 2 OS=Homo sapiens GN=TLE2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.3 0.0006 0.049 3 38 .] 328 362 .. 326 362 .. 0.89 2 ? 6.8 0.0 0.79 64 12 38 .] 383 409 .. 373 409 .. 0.91 3 ! 14.2 0.2 0.0037 0.3 14 38 .] 429 453 .. 419 453 .. 0.85 4 ! 15.9 0.6 0.0011 0.089 4 38 .] 460 495 .. 457 495 .. 0.89 5 ? 7.2 0.0 0.62 51 6 34 .. 501 532 .. 497 534 .. 0.76 6 ? 9.7 0.0 0.099 8 10 37 .. 548 576 .. 541 577 .. 0.84 7 ? 8.5 0.0 0.24 20 11 33 .. 591 613 .. 583 618 .. 0.82 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 0.0006 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +l+tl +H+ v+++ s + + + +G+ +g v++Wd sp|Q04725-2|TLE2_HUMAN 328 QLHTL-AHGEvVCAVTISGSTQHVYTGG-KGCVKVWD 362 68888.8*6657****************.*******9 PP == domain 2 score: 6.8 bits; conditional E-value: 0.79 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04725-2|TLE2_HUMAN 383 YIRSCKLLPDGRSLIVGGEASTLSIWD 409 499999********************9 PP == domain 3 score: 14.2 bits; conditional E-value: 0.0037 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la+spd + +s++ Dg++ +Wd sp|Q04725-2|TLE2_HUMAN 429 YALAVSPDAKVCFSCCSDGNIVVWD 453 6899*******887755*******9 PP == domain 4 score: 15.9 bits; conditional E-value: 0.0011 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r + GH ++ ++++ s++g+ l +G+ D+tvr Wd sp|Q04725-2|TLE2_HUMAN 460 VRQFQGHtDGASCIDISDYGTRLWTGGLDNTVRCWD 495 7889***7779***********747999*******9 PP == domain 5 score: 7.2 bits; conditional E-value: 0.62 EEESS.SS..EEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ss..vtslafspdgawlasGsdDgtv 34 l H +s + sl +p+++wla G++ +v sp|Q04725-2|TLE2_HUMAN 501 QLQQHdFSsqIFSLGHCPNQDWLAVGMESSNV 532 5667863347**************99866555 PP == domain 6 score: 9.7 bits; conditional E-value: 0.099 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W sp|Q04725-2|TLE2_HUMAN 548 HeSCVLSLKFASCGRWFVSTGKDNLLNAW 576 7778**************99999987766 PP == domain 7 score: 8.5 bits; conditional E-value: 0.24 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s++++++++Gs D++ sp|Q04725-2|TLE2_HUMAN 591 SSVLSCDISRNNKYIVTGSGDKK 613 4599**************87986 PP >> sp|Q8IWA0|WDR75_HUMAN WD repeat-containing protein 75 OS=Homo sapiens GN=WDR75 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 0.1 2.8e-08 2.3e-06 2 38 .] 48 86 .. 47 86 .. 0.95 2 ! 21.3 0.1 2.2e-05 0.0018 10 37 .. 201 230 .. 192 231 .. 0.87 3 ? 4.2 0.1 5.2 4.3e+02 9 30 .. 246 268 .. 237 276 .. 0.77 4 ? 6.1 0.0 1.4 1.1e+02 13 36 .. 293 316 .. 284 317 .. 0.85 5 ? 8.1 0.0 0.33 26 10 37 .. 441 473 .. 434 473 .. 0.79 6 ? 4.1 0.1 6 4.8e+02 14 38 .] 502 525 .. 489 525 .. 0.83 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 2.8e-08 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +c+++l GH + vt+++ +p++++ l s+s Dgt+++Wd sp|Q8IWA0|WDR75_HUMAN 48 ECVHILHGHrNLVTGIQLNPNNHLqLYSCSLDGTIKLWD 86 8********777************999***********9 PP == domain 2 score: 21.3 bits; conditional E-value: 2.2e-05 S..SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H..ssvtslafspdgawlasGsdDgtvriW 37 H ++ t++a +p + +asG++Dg++r+W sp|Q8IWA0|WDR75_HUMAN 201 HakNNFTCVACHPTEDCIASGHMDGKIRLW 230 6644489*********************** PP == domain 3 score: 4.2 bits; conditional E-value: 5.2 SSSS.EEEEEEETTSSEEEEEET CS WD40 9 GHss.vtslafspdgawlasGsd 30 H + v +lafs g+ l+sG++ sp|Q8IWA0|WDR75_HUMAN 246 WHHDmVMDLAFSVTGTSLLSGGR 268 452479***************96 PP == domain 4 score: 6.1 bits; conditional E-value: 1.4 EEEEEEETTSSEEEEEETTSEEEE CS WD40 13 vtslafspdgawlasGsdDgtvri 36 + ++++sp g+++++++ D+++ i sp|Q8IWA0|WDR75_HUMAN 293 IEHISVSPAGDLFCTSHSDNKIII 316 889999**********77998865 PP == domain 5 score: 8.1 bits; conditional E-value: 0.33 S.SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgaw....lasGsdDgtvriW 37 H +++t+l+f+ + l+++s+Dg ++W sp|Q8IWA0|WDR75_HUMAN 441 HeDCITALCFCNAEKSeqptLVTASKDGYFKVW 473 76669999855555556666999********** PP == domain 6 score: 4.1 bits; conditional E-value: 6 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 t ++fs dg++la + v iWd sp|Q8IWA0|WDR75_HUMAN 502 TNCCFSEDGSLLAVSF-EEIVTIWD 525 7789********9877.99999998 PP >> sp|P55735|SEC13_HUMAN Protein SEC13 homolog OS=Homo sapiens GN=SEC13 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.1 0.008 0.65 9 38 .] 11 41 .. 4 41 .. 0.85 2 ! 20.3 0.1 4.3e-05 0.0035 5 37 .. 51 86 .. 47 87 .. 0.84 3 ! 15.8 1.0 0.0012 0.096 2 35 .. 94 130 .. 93 131 .. 0.78 4 ? 8.0 0.1 0.35 28 19 38 .] 170 195 .. 140 195 .. 0.71 5 ! 17.2 0.2 0.00042 0.034 3 37 .. 204 243 .. 202 244 .. 0.81 6 ? 12.4 0.9 0.014 1.2 10 38 .] 259 290 .. 254 290 .. 0.83 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 0.008 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 H + +++ + + +g+ la++s D++v+i+d sp|P55735|SEC13_HUMAN 11 SHEDmIHDAQMDYYGTRLATCSSDRSVKIFD 41 67556999999999*******88******98 PP == domain 2 score: 20.3 bits; conditional E-value: 4.3e-05 EEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla..fspdgawlasGsdDgtvriW 37 l+GH ++v+ +a + +g+ las+s+D++v iW sp|P55735|SEC13_HUMAN 51 ADLRGHeGPVWQVAwaHPMYGNILASCSYDRKVIIW 86 5699**999****7667777777************* PP == domain 3 score: 15.8 bits; conditional E-value: 0.0012 EEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgawlasGsdDgtvr 35 ++ ++ GH ssv+s++ +++g la+Gs Dg + sp|P55735|SEC13_HUMAN 94 EKSHEHAGHdSSVNSVCwaPHDYGLILACGSSDGAIS 130 5667888**999****9666666666899988**986 PP == domain 4 score: 8.0 bits; conditional E-value: 0.35 ETTSSE......EEEEETTSEEEEEE CS WD40 19 spdgaw......lasGsdDgtvriWd 38 +p+g+ +asG+ D+ +++W+ sp|P55735|SEC13_HUMAN 170 HPSGQKpnyikrFASGGCDNLIKLWK 195 444444555555789988*******6 PP == domain 5 score: 17.2 bits; conditional E-value: 0.00042 EEEEEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 ++l++H ++v+++ aw +as+s Dg v iW sp|P55735|SEC13_HUMAN 204 EEQKLEAHsDWVRDV------AWapsiglptstIASCSQDGRVFIW 243 567899**666****......66666666999999*********** PP == domain 6 score: 12.4 bits; conditional E-value: 0.014 S..SS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 10 H..ss.vtslafspdgawla.sGsdDgtvriWd 38 H ++ v+++++s + la sG+ D++v +W+ sp|P55735|SEC13_HUMAN 259 HkfNDvVWHVSWSITANILAvSGG-DNKVTLWK 290 6444667***********975888.*******6 PP >> tr|J3QT28|J3QT28_HUMAN Mitotic checkpoint protein BUB3 (Fragment) OS=Homo sapiens GN=BUB3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 0.002 0.16 12 38 .] 16 43 .. 4 43 .. 0.85 2 ? 7.4 0.1 0.55 44 10 37 .. 55 82 .. 48 83 .. 0.82 3 ! 25.0 0.0 1.5e-06 0.00012 9 38 .] 94 124 .. 88 124 .. 0.91 4 ? 3.4 0.0 9.5 7.7e+02 13 38 .] 140 163 .. 129 163 .. 0.78 5 ! 16.6 0.0 0.00066 0.053 8 38 .] 222 262 .. 215 262 .. 0.78 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 0.002 SEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriWd 38 +++s++fsp+ + l+ +s+D +vr++d tr|J3QT28|J3QT28_HUMAN 16 GISSVKFSPNTSQfLLVSSWDTSVRLYD 43 499**********54589********98 PP == domain 2 score: 7.4 bits; conditional E-value: 0.55 S.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriW 37 H + v ++a ++p +aw sG+ D+ +++ tr|J3QT28|J3QT28_HUMAN 55 HtGAVLDCAfYDPTHAW--SGGLDHQLKMH 82 7555988888*******..8**9***9985 PP == domain 3 score: 25.0 bits; conditional E-value: 1.5e-06 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++++ ++p+ + +++Gs+D+tv++Wd tr|J3QT28|J3QT28_HUMAN 94 THdAPIRCVEYCPEVNVMVTGSWDQTVKLWD 124 68777*************************9 PP == domain 4 score: 3.4 bits; conditional E-value: 9.5 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v+ l s +g+ l+ G+ + v +Wd tr|J3QT28|J3QT28_HUMAN 140 VYTL--SVSGDRLIVGTAGRRVLVWD 163 6556..668888888*99*******9 PP == domain 5 score: 16.6 bits; conditional E-value: 0.00066 ESS..SS........EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ss........vtslafspdgawlasGsdDgtvriWd 38 + H + v++++f+ ++ +a+G+ Dg v iWd tr|J3QT28|J3QT28_HUMAN 222 KCHrlKEnnieqiypVNAISFHNIHNTFATGGSDGFVNIWD 262 5555433445666669***************88*******9 PP >> sp|Q8N157|AHI1_HUMAN Jouberin OS=Homo sapiens GN=AHI1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 1 81 14 32 .. 613 633 .. 596 634 .. 0.77 2 ! 27.9 0.3 1.8e-07 1.5e-05 2 38 .] 645 682 .. 644 682 .. 0.90 3 ? 10.2 0.0 0.067 5.4 13 38 .] 700 726 .. 688 726 .. 0.65 4 ! 13.3 0.6 0.007 0.57 4 38 .] 737 772 .. 735 772 .. 0.90 5 ? 12.4 0.0 0.014 1.1 19 38 .] 852 871 .. 834 871 .. 0.88 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 1 EEEEEETTSSEEEEE..ETTS CS WD40 14 tslafspdgawlasG..sdDg 32 +l+fs++g+ la++ s+Dg sp|Q8N157|AHI1_HUMAN 613 FCLDFSHNGRILAAAcaSRDG 633 69*********9854247898 PP == domain 2 score: 27.9 bits; conditional E-value: 1.8e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +r+l GH + +++l++s+d ++++++s Dgt riW+ sp|Q8N157|AHI1_HUMAN 645 RFMRELCGHlNIIYDLSWSKDDHYILTSSSDGTARIWK 682 5689999**999************998877*******6 PP == domain 3 score: 10.2 bits; conditional E-value: 0.067 EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw.lasGsdDgtvriWd 38 v+ +f+p + +++G++D +riW+ sp|Q8N157|AHI1_HUMAN 700 VYTAKFHPAVRElVVTGCYDSMIRIWK 726 444444444444178***********6 PP == domain 4 score: 13.3 bits; conditional E-value: 0.007 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r ++ H s+++sl+f+ +g+ + sG+ g + +W+ sp|Q8N157|AHI1_HUMAN 737 VRQFDVHkSFINSLCFDTEGHHMYSGDCTGVIVVWN 772 688999*777****************77*******8 PP == domain 5 score: 12.4 bits; conditional E-value: 0.014 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 p g++l++Gs+Dg v++W+ sp|Q8N157|AHI1_HUMAN 852 TPCGTFLFAGSEDGIVYVWN 871 6999***************8 PP >> tr|G8JLN6|G8JLN6_HUMAN Jouberin OS=Homo sapiens GN=AHI1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.9 0.4 1.8e-07 1.5e-05 5 38 .] 2 36 .. 1 36 [. 0.91 2 ? 11.7 0.0 0.023 1.9 12 38 .] 53 80 .. 41 80 .. 0.66 3 ! 14.8 0.6 0.0024 0.2 4 38 .] 91 126 .. 89 126 .. 0.90 4 ! 13.8 0.0 0.0052 0.42 19 38 .] 206 225 .. 189 225 .. 0.89 Alignments for each domain: == domain 1 score: 27.9 bits; conditional E-value: 1.8e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + +++l++s+d ++++++s Dgt riW+ tr|G8JLN6|G8JLN6_HUMAN 2 RELCGHlNIIYDLSWSKDDHYILTSSSDGTARIWK 36 7889**999************998877*******6 PP == domain 2 score: 11.7 bits; conditional E-value: 0.023 SEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriWd 38 +v+ +f+p + +++G++D +riW+ tr|G8JLN6|G8JLN6_HUMAN 53 FVYTAKFHPAVRElVVTGCYDSMIRIWK 80 4444444444444178***********6 PP == domain 3 score: 14.8 bits; conditional E-value: 0.0024 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r ++ H s+++sl+f+ +g+ + sG+ g + +W+ tr|G8JLN6|G8JLN6_HUMAN 91 VRQFDVHkSFINSLCFDTEGHHMYSGDCTGVIVVWN 126 688999*777****************77*******8 PP == domain 4 score: 13.8 bits; conditional E-value: 0.0052 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 p g++l++Gs+Dg v++W+ tr|G8JLN6|G8JLN6_HUMAN 206 TPCGTFLFAGSEDGIVYVWN 225 6999***************8 PP >> tr|H3BR25|H3BR25_HUMAN Target of rapamycin complex subunit LST8 (Fragment) OS=Homo sapiens GN=MLST8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.034 2.7 24 37 .. 14 27 .. 7 28 .. 0.82 2 ? 8.8 0.0 0.2 16 3 38 .] 34 75 .. 32 75 .. 0.73 3 ! 24.8 0.1 1.7e-06 0.00014 6 38 .] 86 119 .. 81 119 .. 0.82 4 ! 22.2 0.0 1.1e-05 0.00091 2 38 .] 126 162 .. 125 162 .. 0.96 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.034 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W tr|H3BR25|H3BR25_HUMAN 14 ILATAGYDHTVRFW 27 5888888******* PP == domain 2 score: 8.8 bits; conditional E-value: 0.2 EEEEEESS..SSEEEEEEETTSSEEEEE......ETTSEEEEEE CS WD40 3 clrtltGH..ssvtslafspdgawlasG......sdDgtvriWd 38 c+rt H s v++l + pd +++a++ + +++r++d tr|H3BR25|H3BR25_HUMAN 34 CTRTVQ-HqdSQVNALEVTPDRSMIAAAvqpvslG-YQHIRMYD 75 788875.75444*************9863333234.99999987 PP == domain 3 score: 24.8 bits; conditional E-value: 1.7e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd tr|H3BR25|H3BR25_HUMAN 86 SYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 119 5555445688999********************9 PP == domain 4 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtslafspdgawlasGsdDgtvriWd 38 qc+r++ ++++++ +p++a l+ G+ g ++iWd tr|H3BR25|H3BR25_HUMAN 126 QCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWD 162 8******9999*************************9 PP >> tr|B3KQ29|B3KQ29_HUMAN Transducin-like enhancer protein 4 OS=Homo sapiens GN=TLE4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.1 0.018 1.5 9 38 .] 122 151 .. 115 151 .. 0.83 2 ? 8.3 0.0 0.28 23 12 38 .] 172 198 .. 154 198 .. 0.87 3 ! 13.9 0.2 0.0047 0.38 14 38 .] 218 242 .. 208 242 .. 0.85 4 ! 17.2 0.8 0.00043 0.035 3 38 .] 248 284 .. 246 284 .. 0.86 5 ? 8.0 0.0 0.35 28 7 34 .. 291 321 .. 286 323 .. 0.76 6 ? 10.6 0.1 0.052 4.2 10 37 .. 337 365 .. 331 366 .. 0.85 7 ? 7.5 0.1 0.49 40 11 33 .. 380 402 .. 372 407 .. 0.82 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.018 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 H+ v+++ s + + +G+ +g v++Wd tr|B3KQ29|B3KQ29_HUMAN 122 NHGEvVCAVTISNPTRHVYTGG-KGCVKVWD 151 47555799999999999*****.*******9 PP == domain 2 score: 8.3 bits; conditional E-value: 0.28 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|B3KQ29|B3KQ29_HUMAN 172 YIRSCRLLPDGRTLIVGGEASTLSIWD 198 3889999*******************9 PP == domain 3 score: 13.9 bits; conditional E-value: 0.0047 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd++ +s++ Dg++ +Wd tr|B3KQ29|B3KQ29_HUMAN 218 YALAISPDSKVCFSCCSDGNIAVWD 242 6899*******887755*******9 PP == domain 4 score: 17.2 bits; conditional E-value: 0.00043 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s dg+ l +G+ D+tvr Wd tr|B3KQ29|B3KQ29_HUMAN 248 LVRQFQGHtDGASCIDISNDGTKLWTGGLDNTVRSWD 284 6899****777999999999999647999*******9 PP == domain 5 score: 8.0 bits; conditional E-value: 0.35 EESS..SS.EEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH..ss.vtslafspdgawlasGsdDgtv 34 l H +s + sl ++p g wla G+++ +v tr|B3KQ29|B3KQ29_HUMAN 291 LQQHdfTSqIFSLGYCPTGEWLAVGMENSNV 321 566753226****************988777 PP == domain 6 score: 10.6 bits; conditional E-value: 0.052 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W tr|B3KQ29|B3KQ29_HUMAN 337 HeSCVLSLKFAHCGKWFVSTGKDNLLNAW 365 7778**************99999987766 PP == domain 7 score: 7.5 bits; conditional E-value: 0.49 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|B3KQ29|B3KQ29_HUMAN 380 SSVLSCDISVDDKYIVTGSGDKK 402 45999*************87986 PP >> tr|F5H103|F5H103_HUMAN Proteasomal ATPase-associated factor 1 (Fragment) OS=Homo sapiens GN=PAAF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.1 0.00017 0.014 9 37 .. 73 102 .. 64 103 .. 0.81 2 ! 30.8 0.0 2.2e-08 1.8e-06 2 38 .] 108 145 .. 107 145 .. 0.94 3 ! 22.3 0.2 1e-05 0.00085 2 38 .] 150 187 .. 149 187 .. 0.87 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 0.00017 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 H +s+t+l+ s+ g + ++ +s Dgt +iW tr|F5H103|F5H103_HUMAN 73 IHtKSITCLDISSRGGLgVS-SSTDGTMKIW 102 69999*****9999999565.566******* PP == domain 2 score: 30.8 bits; conditional E-value: 2.2e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+l+GH ++v++++f p+g ++sG++D ++iW+ tr|F5H103|F5H103_HUMAN 108 ELRRVLEGHvFDVNCCRFFPSGLVVLSGGMDAQLKIWS 145 67799****999*************************5 PP == domain 3 score: 22.3 bits; conditional E-value: 1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ t++GH +++ + a + g+ ++s+s+Dgt r+Wd tr|F5H103|F5H103_HUMAN 150 SCVVTFKGHkGGILDTAIVDRGRNVVSASRDGTARLWD 187 6999*****777977777888888899**********9 PP >> sp|O75717|WDHD1_HUMAN WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens GN=WDHD1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.2 9.4e-06 0.00076 6 37 .. 12 40 .. 7 41 .. 0.85 2 ? 6.0 0.0 1.4 1.2e+02 14 37 .. 98 121 .. 66 122 .. 0.86 3 ! 31.6 0.1 1.2e-08 9.6e-07 3 37 .. 128 163 .. 126 164 .. 0.93 4 ? 11.7 0.4 0.024 1.9 16 38 .] 236 258 .. 218 258 .. 0.83 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 9.4e-06 EEESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHssvtslafspdgawlasGsdDgtvriW 37 + +GH t ++f+++g+++++++ Dg vriW sp|O75717|WDHD1_HUMAN 12 HTEGH---TEVCFDDSGSFIVTCGSDGDVRIW 40 44678...89999*******98866******* PP == domain 2 score: 6.0 bits; conditional E-value: 1.4 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 +++ f+ dg+ +a+Gs D v+i sp|O75717|WDHD1_HUMAN 98 NHVVFNGDGTKIAAGSSDFLVKIV 121 5778***********98****995 PP == domain 3 score: 31.6 bits; conditional E-value: 1.2e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++t++GH +v sl+f+p +las+s Dg+vr+W sp|O75717|WDHD1_HUMAN 128 QQKTFRGHdAPVLSLSFDPKDIFLASASCDGSVRVW 163 689*****888**************9989******* PP == domain 4 score: 11.7 bits; conditional E-value: 0.024 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 + +sp g++la+Gs +g + +W+ sp|O75717|WDHD1_HUMAN 236 VTWSPCGQYLAAGSINGLIIVWN 258 55********************8 PP >> sp|P55735-2|SEC13_HUMAN Isoform 2 of Protein SEC13 homolog OS=Homo sapiens GN=SEC13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.056 4.6 19 38 .] 8 27 .. 2 27 .. 0.82 2 ! 20.4 0.1 4.1e-05 0.0033 5 37 .. 37 72 .. 33 73 .. 0.84 3 ! 15.9 1.0 0.0011 0.09 2 35 .. 80 116 .. 79 117 .. 0.78 4 ? 8.1 0.1 0.33 27 19 38 .] 156 181 .. 126 181 .. 0.71 5 ! 17.3 0.2 0.0004 0.032 3 37 .. 190 229 .. 188 230 .. 0.81 6 ? 12.5 0.9 0.013 1.1 10 38 .] 245 276 .. 240 276 .. 0.83 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.056 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 + +g+ la++s D++v+i+d sp|P55735-2|SEC13_HUMAN 8 DYYGTRLATCSSDRSVKIFD 27 6688899*9988******98 PP == domain 2 score: 20.4 bits; conditional E-value: 4.1e-05 EEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla..fspdgawlasGsdDgtvriW 37 l+GH ++v+ +a + +g+ las+s+D++v iW sp|P55735-2|SEC13_HUMAN 37 ADLRGHeGPVWQVAwaHPMYGNILASCSYDRKVIIW 72 5699**999****7667777777************* PP == domain 3 score: 15.9 bits; conditional E-value: 0.0011 EEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgawlasGsdDgtvr 35 ++ ++ GH ssv+s++ +++g la+Gs Dg + sp|P55735-2|SEC13_HUMAN 80 EKSHEHAGHdSSVNSVCwaPHDYGLILACGSSDGAIS 116 5667888**999****9666666666899988**986 PP == domain 4 score: 8.1 bits; conditional E-value: 0.33 ETTSSE......EEEEETTSEEEEEE CS WD40 19 spdgaw......lasGsdDgtvriWd 38 +p+g+ +asG+ D+ +++W+ sp|P55735-2|SEC13_HUMAN 156 HPSGQKpnyikrFASGGCDNLIKLWK 181 444444555555789988*******6 PP == domain 5 score: 17.3 bits; conditional E-value: 0.0004 EEEEEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 ++l++H ++v+++ aw +as+s Dg v iW sp|P55735-2|SEC13_HUMAN 190 EEQKLEAHsDWVRDV------AWapsiglptstIASCSQDGRVFIW 229 567899**666****......66666666999999*********** PP == domain 6 score: 12.5 bits; conditional E-value: 0.013 S..SS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 10 H..ss.vtslafspdgawla.sGsdDgtvriWd 38 H ++ v+++++s + la sG+ D++v +W+ sp|P55735-2|SEC13_HUMAN 245 HkfNDvVWHVSWSITANILAvSGG-DNKVTLWK 276 6444667***********975888.*******6 PP >> sp|Q9Y6I7-4|WSB1_HUMAN Isoform 4 of WD repeat and SOCS box-containing protein 1 OS=Homo sapiens GN=WSB1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.3 0.1 1.7e-09 1.4e-07 4 38 .] 47 82 .. 44 82 .. 0.92 2 ! 17.0 0.0 0.00051 0.041 11 37 .. 108 136 .. 89 137 .. 0.82 3 ! 18.7 0.2 0.00015 0.012 15 37 .. 154 176 .. 147 176 .. 0.93 Alignments for each domain: == domain 1 score: 34.3 bits; conditional E-value: 1.7e-09 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r+l+GH +v +++fspdga+la++s+D v+iWd sp|Q9Y6I7-4|WSB1_HUMAN 47 IRKLEGHhHDVVACDFSPDGALLATASYDTRVYIWD 82 7899***77799***********************9 PP == domain 2 score: 17.0 bits; conditional E-value: 0.00051 SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ss..vtslafspdgawlasGsdDgtvriW 37 ++ v+s++fs+dg +as dD+ vr+W sp|Q9Y6I7-4|WSB1_HUMAN 108 NDrwVRSVSFSHDGLHVASLADDKMVRFW 136 4467************985488******* PP == domain 3 score: 18.7 bits; conditional E-value: 0.00015 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++afs dg+ la+G+ Dg+v++W sp|Q9Y6I7-4|WSB1_HUMAN 154 CCAFSTDGSVLAAGTHDGSVYFW 176 999***********88******* PP >> tr|F5H3I1|F5H3I1_HUMAN Proteasomal ATPase-associated factor 1 (Fragment) OS=Homo sapiens GN=PAAF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.1 0.00018 0.015 9 37 .. 73 102 .. 64 103 .. 0.81 2 ! 30.7 0.0 2.3e-08 1.9e-06 2 38 .] 108 145 .. 107 145 .. 0.94 3 ! 22.2 0.2 1.1e-05 0.0009 2 38 .] 150 187 .. 149 187 .. 0.87 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 0.00018 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 H +s+t+l+ s+ g + ++ +s Dgt +iW tr|F5H3I1|F5H3I1_HUMAN 73 IHtKSITCLDISSRGGLgVS-SSTDGTMKIW 102 69999*****9999999565.566******* PP == domain 2 score: 30.7 bits; conditional E-value: 2.3e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+l+GH ++v++++f p+g ++sG++D ++iW+ tr|F5H3I1|F5H3I1_HUMAN 108 ELRRVLEGHvFDVNCCRFFPSGLVVLSGGMDAQLKIWS 145 67799****999*************************5 PP == domain 3 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ t++GH +++ + a + g+ ++s+s+Dgt r+Wd tr|F5H3I1|F5H3I1_HUMAN 150 SCVVTFKGHkGGILDTAIVDRGRNVVSASRDGTARLWD 187 6999*****777977777888888899**********9 PP >> tr|H0YNI7|H0YNI7_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.1 0.0051 0.41 6 38 .] 63 94 .. 58 94 .. 0.83 2 ? 7.4 0.0 0.54 44 12 38 .] 115 141 .. 103 141 .. 0.90 3 ! 13.0 0.1 0.0088 0.71 14 38 .] 161 185 .. 151 185 .. 0.85 4 ! 17.4 1.3 0.00037 0.03 3 38 .] 191 227 .. 189 227 .. 0.88 5 ? 7.1 0.0 0.64 52 7 32 .. 234 262 .. 229 266 .. 0.74 6 ? 9.5 0.1 0.12 9.4 10 37 .. 280 308 .. 273 309 .. 0.85 7 ? 8.7 0.1 0.21 17 11 33 .. 323 345 .. 315 350 .. 0.82 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.0051 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|H0YNI7|H0YNI7_HUMAN 63 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 94 55.48555799999999999*****.*******9 PP == domain 2 score: 7.4 bits; conditional E-value: 0.54 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|H0YNI7|H0YNI7_HUMAN 115 YIRSCKLLPDGRTLIVGGEASTLTIWD 141 49999*********************9 PP == domain 3 score: 13.0 bits; conditional E-value: 0.0088 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd tr|H0YNI7|H0YNI7_HUMAN 161 YALAISPDAKVCFSCCSDGNIAVWD 185 6899*******887755*******9 PP == domain 4 score: 17.4 bits; conditional E-value: 0.00037 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd tr|H0YNI7|H0YNI7_HUMAN 191 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 227 6899****77799***9999999747999*******9 PP == domain 5 score: 7.1 bits; conditional E-value: 0.64 EESS..SS.EEEEEEETTSSEEEEEETTS CS WD40 7 ltGH..ss.vtslafspdgawlasGsdDg 32 l H +s + sl ++p g wla G++ tr|H0YNI7|H0YNI7_HUMAN 234 LQQHdfTSqIFSLGYCPTGEWLAVGMESS 262 566753226**************997555 PP == domain 6 score: 9.5 bits; conditional E-value: 0.12 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W tr|H0YNI7|H0YNI7_HUMAN 280 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 308 7778**************99999987766 PP == domain 7 score: 8.7 bits; conditional E-value: 0.21 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|H0YNI7|H0YNI7_HUMAN 323 SSVLSCDISADDKYIVTGSGDKK 345 4599**************87986 PP >> tr|C9JYB3|C9JYB3_HUMAN WD repeat and HMG-box DNA-binding protein 1 (Fragment) OS=Homo sapiens GN=WDHD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.1 7.3e-07 5.9e-05 6 37 .. 12 40 .. 6 41 .. 0.84 2 ? 9.6 0.1 0.11 8.5 14 37 .. 98 121 .. 58 122 .. 0.84 3 ! 35.2 0.1 8.9e-10 7.2e-08 3 37 .. 128 163 .. 126 164 .. 0.93 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 7.3e-07 EEESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHssvtslafspdgawlasGsdDgtvriW 37 + +GH t ++f+++g+++++++ Dg vriW tr|C9JYB3|C9JYB3_HUMAN 12 HTEGH---TEVCFDDSGSFIVTCGSDGDVRIW 40 44677...89999*******98866******* PP == domain 2 score: 9.6 bits; conditional E-value: 0.11 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 +++ f+ dg+ +a+Gs D v+i tr|C9JYB3|C9JYB3_HUMAN 98 NHVVFNGDGTKIAAGSSDFLVKIV 121 5777***********98****995 PP == domain 3 score: 35.2 bits; conditional E-value: 8.9e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++t++GH +v sl+f+p +las+s Dg+vr+W tr|C9JYB3|C9JYB3_HUMAN 128 QQKTFRGHdAPVLSLSFDPKDIFLASASCDGSVRVW 163 689*****888**************9989******* PP >> tr|B4DXJ1|B4DXJ1_HUMAN Protein SEC13 homolog OS=Homo sapiens GN=SEC13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.1 0.009 0.73 9 38 .] 57 87 .. 48 87 .. 0.85 2 ! 20.1 0.1 5.2e-05 0.0042 5 37 .. 97 132 .. 93 133 .. 0.84 3 ! 15.5 1.0 0.0014 0.12 2 35 .. 140 176 .. 139 177 .. 0.78 4 ? 7.7 0.1 0.42 34 19 38 .] 216 241 .. 186 241 .. 0.71 5 ! 16.9 0.2 0.00051 0.041 3 37 .. 250 289 .. 248 290 .. 0.81 6 ? 12.2 0.7 0.016 1.3 10 38 .] 305 336 .. 301 336 .. 0.83 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.009 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 H + +++ + + +g+ la++s D++v+i+d tr|B4DXJ1|B4DXJ1_HUMAN 57 SHEDmIHDAQMDYYGTRLATCSSDRSVKIFD 87 67556999999999*******88******98 PP == domain 2 score: 20.1 bits; conditional E-value: 5.2e-05 EEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla..fspdgawlasGsdDgtvriW 37 l+GH ++v+ +a + +g+ las+s+D++v iW tr|B4DXJ1|B4DXJ1_HUMAN 97 ADLRGHeGPVWQVAwaHPMYGNILASCSYDRKVIIW 132 5699**999****7667777777************* PP == domain 3 score: 15.5 bits; conditional E-value: 0.0014 EEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgawlasGsdDgtvr 35 ++ ++ GH ssv+s++ +++g la+Gs Dg + tr|B4DXJ1|B4DXJ1_HUMAN 140 EKSHEHAGHdSSVNSVCwaPHDYGLILACGSSDGAIS 176 5667888**999****9666666666899988**986 PP == domain 4 score: 7.7 bits; conditional E-value: 0.42 ETTSSE......EEEEETTSEEEEEE CS WD40 19 spdgaw......lasGsdDgtvriWd 38 +p+g+ +asG+ D+ +++W+ tr|B4DXJ1|B4DXJ1_HUMAN 216 HPSGQKpnyikrFASGGCDNLIKLWK 241 444444555555789988*******6 PP == domain 5 score: 16.9 bits; conditional E-value: 0.00051 EEEEEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 ++l++H ++v+++ aw +as+s Dg v iW tr|B4DXJ1|B4DXJ1_HUMAN 250 EEQKLEAHsDWVRDV------AWapsiglptstIASCSQDGRVFIW 289 567899**666****......66666666999999*********** PP == domain 6 score: 12.2 bits; conditional E-value: 0.016 S..SS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 10 H..ss.vtslafspdgawla.sGsdDgtvriWd 38 H ++ v+++++s + la sG+ D++v +W+ tr|B4DXJ1|B4DXJ1_HUMAN 305 HkfNDvVWHVSWSITANILAvSGG-DNKVTLWK 336 6444667***********975888.*******6 PP >> sp|Q04725|TLE2_HUMAN Transducin-like enhancer protein 2 OS=Homo sapiens GN=TLE2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.3 0.00075 0.06 3 38 .] 450 484 .. 448 484 .. 0.89 2 ? 6.6 0.0 0.98 79 12 38 .] 505 531 .. 495 531 .. 0.91 3 ! 13.9 0.2 0.0046 0.37 14 38 .] 551 575 .. 541 575 .. 0.85 4 ! 15.6 0.6 0.0014 0.11 4 38 .] 582 617 .. 579 617 .. 0.89 5 ? 6.9 0.0 0.77 63 6 34 .. 623 654 .. 619 656 .. 0.76 6 ? 9.4 0.0 0.12 9.9 10 37 .. 670 698 .. 663 699 .. 0.84 7 ? 8.2 0.0 0.3 24 11 33 .. 713 735 .. 705 740 .. 0.82 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 0.00075 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +l+tl +H+ v+++ s + + + +G+ +g v++Wd sp|Q04725|TLE2_HUMAN 450 QLHTL-AHGEvVCAVTISGSTQHVYTGG-KGCVKVWD 484 67888.8*6657****************.*******9 PP == domain 2 score: 6.6 bits; conditional E-value: 0.98 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04725|TLE2_HUMAN 505 YIRSCKLLPDGRSLIVGGEASTLSIWD 531 499999********************9 PP == domain 3 score: 13.9 bits; conditional E-value: 0.0046 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la+spd + +s++ Dg++ +Wd sp|Q04725|TLE2_HUMAN 551 YALAVSPDAKVCFSCCSDGNIVVWD 575 6899*******887755*******9 PP == domain 4 score: 15.6 bits; conditional E-value: 0.0014 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r + GH ++ ++++ s++g+ l +G+ D+tvr Wd sp|Q04725|TLE2_HUMAN 582 VRQFQGHtDGASCIDISDYGTRLWTGGLDNTVRCWD 617 7889***7779***********747999*******9 PP == domain 5 score: 6.9 bits; conditional E-value: 0.77 EEESS.SS..EEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ss..vtslafspdgawlasGsdDgtv 34 l H +s + sl +p+++wla G++ +v sp|Q04725|TLE2_HUMAN 623 QLQQHdFSsqIFSLGHCPNQDWLAVGMESSNV 654 5667863347**************99866555 PP == domain 6 score: 9.4 bits; conditional E-value: 0.12 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W sp|Q04725|TLE2_HUMAN 670 HeSCVLSLKFASCGRWFVSTGKDNLLNAW 698 7778**************99999987766 PP == domain 7 score: 8.2 bits; conditional E-value: 0.3 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s++++++++Gs D++ sp|Q04725|TLE2_HUMAN 713 SSVLSCDISRNNKYIVTGSGDKK 735 4599**************87986 PP >> tr|K7EMK7|K7EMK7_HUMAN Transducin-like enhancer protein 2 OS=Homo sapiens GN=TLE2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.3 0.00075 0.061 3 38 .] 451 485 .. 449 485 .. 0.89 2 ? 6.6 0.0 0.98 80 12 38 .] 506 532 .. 496 532 .. 0.91 3 ! 13.9 0.2 0.0046 0.37 14 38 .] 552 576 .. 542 576 .. 0.85 4 ! 15.6 0.6 0.0014 0.11 4 38 .] 583 618 .. 580 618 .. 0.89 5 ? 6.9 0.0 0.78 63 6 34 .. 624 655 .. 620 657 .. 0.76 6 ? 9.4 0.0 0.12 9.9 10 37 .. 671 699 .. 664 700 .. 0.84 7 ? 8.2 0.0 0.3 24 11 33 .. 714 736 .. 706 741 .. 0.82 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 0.00075 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +l+tl +H+ v+++ s + + + +G+ +g v++Wd tr|K7EMK7|K7EMK7_HUMAN 451 QLHTL-AHGEvVCAVTISGSTQHVYTGG-KGCVKVWD 485 67888.8*6657****************.*******9 PP == domain 2 score: 6.6 bits; conditional E-value: 0.98 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|K7EMK7|K7EMK7_HUMAN 506 YIRSCKLLPDGRSLIVGGEASTLSIWD 532 499999********************9 PP == domain 3 score: 13.9 bits; conditional E-value: 0.0046 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la+spd + +s++ Dg++ +Wd tr|K7EMK7|K7EMK7_HUMAN 552 YALAVSPDAKVCFSCCSDGNIVVWD 576 6899*******887755*******9 PP == domain 4 score: 15.6 bits; conditional E-value: 0.0014 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r + GH ++ ++++ s++g+ l +G+ D+tvr Wd tr|K7EMK7|K7EMK7_HUMAN 583 VRQFQGHtDGASCIDISDYGTRLWTGGLDNTVRCWD 618 7889***7779***********747999*******9 PP == domain 5 score: 6.9 bits; conditional E-value: 0.78 EEESS.SS..EEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ss..vtslafspdgawlasGsdDgtv 34 l H +s + sl +p+++wla G++ +v tr|K7EMK7|K7EMK7_HUMAN 624 QLQQHdFSsqIFSLGHCPNQDWLAVGMESSNV 655 5667863347**************99866555 PP == domain 6 score: 9.4 bits; conditional E-value: 0.12 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W tr|K7EMK7|K7EMK7_HUMAN 671 HeSCVLSLKFASCGRWFVSTGKDNLLNAW 699 7778**************99999987766 PP == domain 7 score: 8.2 bits; conditional E-value: 0.3 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s++++++++Gs D++ tr|K7EMK7|K7EMK7_HUMAN 714 SSVLSCDISRNNKYIVTGSGDKK 736 4599**************87986 PP >> tr|A8MXL6|A8MXL6_HUMAN Protein SEC13 homolog OS=Homo sapiens GN=SEC13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.051 4.1 19 38 .] 8 27 .. 2 27 .. 0.82 2 ! 20.6 0.1 3.6e-05 0.0029 5 37 .. 37 72 .. 33 73 .. 0.84 3 ! 16.0 1.0 0.00099 0.08 2 35 .. 80 116 .. 79 117 .. 0.78 4 ? 8.2 0.1 0.29 24 19 38 .] 156 181 .. 126 181 .. 0.71 5 ! 17.5 0.2 0.00035 0.029 3 37 .. 190 229 .. 188 230 .. 0.81 6 ? 6.3 0.1 1.2 97 10 32 .. 245 270 .. 240 271 .. 0.78 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.051 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 + +g+ la++s D++v+i+d tr|A8MXL6|A8MXL6_HUMAN 8 DYYGTRLATCSSDRSVKIFD 27 6688899*9988******98 PP == domain 2 score: 20.6 bits; conditional E-value: 3.6e-05 EEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtsla..fspdgawlasGsdDgtvriW 37 l+GH ++v+ +a + +g+ las+s+D++v iW tr|A8MXL6|A8MXL6_HUMAN 37 ADLRGHeGPVWQVAwaHPMYGNILASCSYDRKVIIW 72 5699**999****7667777777************* PP == domain 3 score: 16.0 bits; conditional E-value: 0.00099 EEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgawlasGsdDgtvr 35 ++ ++ GH ssv+s++ +++g la+Gs Dg + tr|A8MXL6|A8MXL6_HUMAN 80 EKSHEHAGHdSSVNSVCwaPHDYGLILACGSSDGAIS 116 5667888**999****9666666666899988**986 PP == domain 4 score: 8.2 bits; conditional E-value: 0.29 ETTSSE......EEEEETTSEEEEEE CS WD40 19 spdgaw......lasGsdDgtvriWd 38 +p+g+ +asG+ D+ +++W+ tr|A8MXL6|A8MXL6_HUMAN 156 HPSGQKpnyikrFASGGCDNLIKLWK 181 444444555555789988*******6 PP == domain 5 score: 17.5 bits; conditional E-value: 0.00035 EEEEEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 ++l++H ++v+++ aw +as+s Dg v iW tr|A8MXL6|A8MXL6_HUMAN 190 EEQKLEAHsDWVRDV------AWapsiglptstIASCSQDGRVFIW 229 567899**666****......66666666999999*********** PP == domain 6 score: 6.3 bits; conditional E-value: 1.2 S..SS.EEEEEEETTSSEEE.EEETTS CS WD40 10 H..ss.vtslafspdgawla.sGsdDg 32 H ++ v+++++s + la sG+ D+ tr|A8MXL6|A8MXL6_HUMAN 245 HkfNDvVWHVSWSITANILAvSGG-DN 270 6444667***********975888.75 PP >> sp|Q9BYB4|GNB1L_HUMAN Guanine nucleotide-binding protein subunit beta-like protein 1 OS=Homo sapiens GN=GNB1L PE=1 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.0 0.18 15 3 38 .] 12 53 .. 10 53 .. 0.78 2 ? 10.7 0.0 0.049 4 4 38 .] 60 96 .. 57 96 .. 0.87 3 ? 10.2 0.0 0.068 5.5 21 38 .] 177 194 .. 148 194 .. 0.81 4 ? 10.0 0.0 0.078 6.3 12 37 .. 254 280 .. 240 282 .. 0.78 5 ! 20.4 0.0 4e-05 0.0032 2 38 .] 286 322 .. 285 322 .. 0.89 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.18 EEEEEESS.SSEEEEEEETTSSE...........EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw...........lasGsdDgtvriWd 38 ++ +l+G s+v++l + l+sGs g v+iW+ sp|Q9BYB4|GNB1L_HUMAN 12 PQFVLRGTqSPVHALH------FcegaqaqgrplLFSGSQSGLVHIWS 53 78899999888*9995......44444447777689***********5 PP == domain 2 score: 10.7 bits; conditional E-value: 0.049 EEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 ++tl+GH ++vt l++ p g+ l+s ++D ++ +Wd sp|Q9BYB4|GNB1L_HUMAN 60 VTTLDGHggQCVTWLQTLPQGRQLLSQGRDLKLCLWD 96 789****6444**************7688*******9 PP == domain 3 score: 10.2 bits; conditional E-value: 0.068 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 + ++l++G +Dg+v +Wd sp|Q9BYB4|GNB1L_HUMAN 177 SRPLLLAGYEDGSVVLWD 194 4566889**********9 PP == domain 4 score: 10.0 bits; conditional E-value: 0.078 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 + + + pd + la++++D+ +r++ sp|Q9BYB4|GNB1L_HUMAN 254 PgIAEVTIRPDRKILATAGWDHRIRVF 280 357777889****************96 PP == domain 5 score: 20.4 bits; conditional E-value: 4e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+l +l H v ++af dg + a+Gs+D+ + +W+ sp|Q9BYB4|GNB1L_HUMAN 286 QPLAVLAFHsAAVQCVAFTADGLL-AAGSKDQRISLWS 322 78999999*555************.67**********5 PP >> sp|Q9BRP4-2|PAAF1_HUMAN Isoform 2 of Proteasomal ATPase-associated factor 1 OS=Homo sapiens GN=PAAF1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.2 0.00035 0.029 9 37 .. 73 102 .. 65 103 .. 0.81 2 ! 29.9 0.0 4.2e-08 3.4e-06 2 38 .] 108 145 .. 107 145 .. 0.94 3 ! 21.4 0.2 2e-05 0.0017 2 38 .] 150 187 .. 149 187 .. 0.87 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 0.00035 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 H +s+t+l+ s+ g + ++ +s Dgt +iW sp|Q9BRP4-2|PAAF1_HUMAN 73 IHtKSITCLDISSRGGLgVS-SSTDGTMKIW 102 59999*****9999999565.566******* PP == domain 2 score: 29.9 bits; conditional E-value: 4.2e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+l+GH ++v++++f p+g ++sG++D ++iW+ sp|Q9BRP4-2|PAAF1_HUMAN 108 ELRRVLEGHvFDVNCCRFFPSGLVVLSGGMDAQLKIWS 145 67799****999*************************5 PP == domain 3 score: 21.4 bits; conditional E-value: 2e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ t++GH +++ + a + g+ ++s+s+Dgt r+Wd sp|Q9BRP4-2|PAAF1_HUMAN 150 SCVVTFKGHkGGILDTAIVDRGRNVVSASRDGTARLWD 187 6999*****777977777888888899**********9 PP >> sp|Q9NNW5|WDR6_HUMAN WD repeat-containing protein 6 OS=Homo sapiens GN=WDR6 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 0.0005 0.04 6 38 .] 204 237 .. 200 237 .. 0.88 2 ? 7.9 0.3 0.37 30 2 38 .] 249 284 .. 248 284 .. 0.77 3 ! 21.1 0.1 2.6e-05 0.0021 2 37 .. 288 325 .. 287 326 .. 0.89 4 ? 12.0 0.2 0.019 1.6 2 37 .. 971 1010 .. 970 1011 .. 0.76 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 0.0005 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++GH + + s+++ ++ +la++s+D++vriW+ sp|Q9NNW5|WDR6_HUMAN 204 RISGHvGIIFSMSYLESKGLLATASEDRSVRIWK 237 568**6668***99999999*************6 PP == domain 2 score: 7.9 bits; conditional E-value: 0.37 EEEEEEESSSS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgaw....lasGsdDgtvriWd 38 q+++++ GHs v+ + ++ l+s+++D+ + +W+ sp|Q9NNW5|WDR6_HUMAN 249 QNIGHCFGHSArVWQV------KLlenyLISAGEDCVCLVWS 284 5677777994459999......775666789999*******5 PP == domain 3 score: 21.1 bits; conditional E-value: 2.6e-05 EEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss..vtslafspdgawlasGsdDgtvriW 37 + l+ ++GH++ ++++a + +aw+++G+dD +r+W sp|Q9NNW5|WDR6_HUMAN 288 EILQAFRGHQGrgIRAIAAHERQAWVITGGDDSGIRLW 325 67889****4458************************* PP == domain 4 score: 12.0 bits; conditional E-value: 0.019 EEEEEEESS.SSEEEEE..EETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgaw.lasGsdDgtvriW 37 ++ tl +H ++++sl ++g+ +asGs+Dg+++++ sp|Q9NNW5|WDR6_HUMAN 971 TPSLTLQAHsCGINSLHtlPTREGHHlVASGSEDGSLHVF 1010 5678999**777****887555555535799******986 PP >> sp|Q7Z5U6|WDR53_HUMAN WD repeat-containing protein 53 OS=Homo sapiens GN=WDR53 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.1 2.8 2.3e+02 8 30 .. 7 29 .. 3 41 .. 0.73 2 ? 4.6 0.1 4.1 3.3e+02 4 24 .. 43 65 .. 39 77 .. 0.68 3 ? 9.0 0.0 0.17 14 9 36 .. 90 120 .. 80 122 .. 0.80 4 ? 12.1 0.0 0.018 1.5 3 38 .] 128 165 .. 126 165 .. 0.87 5 ? 8.9 0.0 0.18 15 14 37 .. 201 224 .. 191 225 .. 0.79 6 ! 25.5 0.0 1e-06 8.3e-05 7 38 .] 237 269 .. 230 269 .. 0.90 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 2.8 ESS.SSEEEEEEETTSSEEEEEET CS WD40 8 tGH.ssvtslafspdgawlasGsd 30 GH s+v +l s++g + asG + sp|Q7Z5U6|WDR53_HUMAN 7 GGHsSPVLCLNASKEGLL-ASGAE 29 49*888****88888877.78753 PP == domain 2 score: 4.6 bits; conditional E-value: 4.1 EEE..EESSSSEEEEEEETTSSE CS WD40 4 lrt..ltGHssvtslafspdgaw 24 l++ + G ++vts+ fsp+ + sp|Q7Z5U6|WDR53_HUMAN 43 LGHtrFQGADDVTSVLFSPSCPT 65 44412345566*******99776 PP == domain 3 score: 9.0 bits; conditional E-value: 0.17 SS.SS..EEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ss..vtslafspdgawlasGsdDgtvri 36 H + +++l+ ++ ++las++d g ++i sp|Q7Z5U6|WDR53_HUMAN 90 FHvNEeeINCLSLNQTENLLASADDSGAIKI 120 3554467***************999999998 PP == domain 4 score: 12.1 bits; conditional E-value: 0.018 EEEEEESSSSE.EEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGHssv.tslafspdgaw.lasGsdDgtvriWd 38 +r+l+ Hs++ +s+af p + l+s++ D v++W+ sp|Q7Z5U6|WDR53_HUMAN 128 VIRSLKRHSNIcSSVAFRPQRPQsLVSCGLDMQVMLWS 165 68999***77879**999999998889999*******5 PP == domain 5 score: 8.9 bits; conditional E-value: 0.18 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 +s+++ + g+ +++G +Dg+vri+ sp|Q7Z5U6|WDR53_HUMAN 201 HSISVASCGNIFSCGAEDGKVRIF 224 3555567799999999******97 PP == domain 6 score: 25.5 bits; conditional E-value: 1e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++GH s+v+ ++f p++ +l++G+ Dg++ +Wd sp|Q7Z5U6|WDR53_HUMAN 237 FKGHtSGVSQVCFLPESYLLLTGGNDGKITLWD 269 79**888*************************9 PP >> sp|Q9BRP4|PAAF1_HUMAN Proteasomal ATPase-associated factor 1 OS=Homo sapiens GN=PAAF1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.2 0.00038 0.031 9 37 .. 90 119 .. 82 120 .. 0.81 2 ! 29.8 0.0 4.5e-08 3.6e-06 2 38 .] 125 162 .. 124 162 .. 0.94 3 ! 21.3 0.2 2.2e-05 0.0018 2 38 .] 167 204 .. 166 204 .. 0.87 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 0.00038 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 H +s+t+l+ s+ g + ++ +s Dgt +iW sp|Q9BRP4|PAAF1_HUMAN 90 IHtKSITCLDISSRGGLgVS-SSTDGTMKIW 119 59999*****9999999565.566******* PP == domain 2 score: 29.8 bits; conditional E-value: 4.5e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+l+GH ++v++++f p+g ++sG++D ++iW+ sp|Q9BRP4|PAAF1_HUMAN 125 ELRRVLEGHvFDVNCCRFFPSGLVVLSGGMDAQLKIWS 162 67799****999*************************5 PP == domain 3 score: 21.3 bits; conditional E-value: 2.2e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ t++GH +++ + a + g+ ++s+s+Dgt r+Wd sp|Q9BRP4|PAAF1_HUMAN 167 SCVVTFKGHkGGILDTAIVDRGRNVVSASRDGTARLWD 204 6999*****777977777888888899**********9 PP >> tr|F5H0C4|F5H0C4_HUMAN Proteasomal ATPase-associated factor 1 OS=Homo sapiens GN=PAAF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.2 0.00038 0.031 9 37 .. 91 120 .. 83 121 .. 0.81 2 ! 29.8 0.0 4.5e-08 3.6e-06 2 38 .] 126 163 .. 125 163 .. 0.94 3 ! 21.3 0.2 2.2e-05 0.0018 2 38 .] 168 205 .. 167 205 .. 0.87 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 0.00038 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 H +s+t+l+ s+ g + ++ +s Dgt +iW tr|F5H0C4|F5H0C4_HUMAN 91 IHtKSITCLDISSRGGLgVS-SSTDGTMKIW 120 59999*****9999999565.566******* PP == domain 2 score: 29.8 bits; conditional E-value: 4.5e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+l+GH ++v++++f p+g ++sG++D ++iW+ tr|F5H0C4|F5H0C4_HUMAN 126 ELRRVLEGHvFDVNCCRFFPSGLVVLSGGMDAQLKIWS 163 67799****999*************************5 PP == domain 3 score: 21.3 bits; conditional E-value: 2.2e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ t++GH +++ + a + g+ ++s+s+Dgt r+Wd tr|F5H0C4|F5H0C4_HUMAN 168 SCVVTFKGHkGGILDTAIVDRGRNVVSASRDGTARLWD 205 6999*****777977777888888899**********9 PP >> sp|Q96MT7-2|WDR52_HUMAN Isoform 2 of WD repeat-containing protein 52 OS=Homo sapiens GN=WDR52 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 8.7 7e+02 16 38 .] 234 258 .. 231 258 .. 0.85 2 ? 10.5 0.0 0.058 4.7 9 38 .] 365 393 .. 358 393 .. 0.72 3 ? 9.2 0.0 0.15 12 7 38 .] 466 498 .. 461 498 .. 0.84 4 ! 17.6 0.0 0.00032 0.026 3 36 .. 567 601 .. 565 603 .. 0.89 5 ? 11.7 0.2 0.024 1.9 7 38 .] 851 886 .. 848 886 .. 0.83 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.7 EEEETTSSEEEE.EET.TSEEEEEE CS WD40 16 lafspdgawlas.Gsd.DgtvriWd 38 ++f+ +g++las Gs D t+ iW+ sp|Q96MT7-2|WDR52_HUMAN 234 VDFNYSGNLLASvGSNpDYTLTIWN 258 68999*****9636668*******8 PP == domain 2 score: 10.5 bits; conditional E-value: 0.058 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H ++++ + +g ++ Gs Dg vriWd sp|Q96MT7-2|WDR52_HUMAN 365 CHnGPINQI-MLYEGEVITVGS-DGYVRIWD 393 564447666.44455558889*.*******9 PP == domain 3 score: 9.2 bits; conditional E-value: 0.15 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ H + + ++a+sp ++a+ D++vri+d sp|Q96MT7-2|WDR52_HUMAN 466 FSFHsGAIEAVAVSPLTYLMATTALDCSVRIYD 498 4578445*************99888*******8 PP == domain 4 score: 17.6 bits; conditional E-value: 0.00032 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 + ++++ H +vt+la+ +dg la+Gs+D+tv + sp|Q96MT7-2|WDR52_HUMAN 567 LKQVFKPHtACVTALAYERDGEILATGSKDQTVFF 601 6688999*777*********************976 PP == domain 5 score: 11.7 bits; conditional E-value: 0.024 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 + H ++ + s+a+s d ++l++++ Dg++ +++ sp|Q96MT7-2|WDR52_HUMAN 851 FNMHdNNygcIKSIANSFDDRFLVTAGADGNIFVFN 886 55676446779*************9999****9986 PP >> sp|O43379-3|WDR62_HUMAN Isoform 3 of WD repeat-containing protein 62 OS=Homo sapiens GN=WDR62 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 6.1e-05 0.0049 2 38 .] 102 141 .. 101 141 .. 0.90 2 ! 13.3 0.0 0.0074 0.6 6 38 .] 150 185 .. 145 185 .. 0.80 3 ? 10.7 0.1 0.048 3.9 13 37 .. 201 224 .. 192 224 .. 0.88 4 ? 6.9 0.0 0.74 60 15 37 .. 302 320 .. 291 321 .. 0.75 5 ! 15.4 0.1 0.0016 0.13 15 38 .] 364 387 .. 348 387 .. 0.83 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 6.1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++++++ + +s ++lafspdg+++++G + + vriWd sp|O43379-3|WDR62_HUMAN 102 KQQHIFNTArKSLSALAFSPDGKYIVTGenGHRPAVRIWD 141 678999988899***************98866*******9 PP == domain 2 score: 13.3 bits; conditional E-value: 0.0074 EEESSSS.EEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlas.G..sdDgtvriWd 38 + GH+ v ++afsp+ + ++s G + D + +Wd sp|O43379-3|WDR62_HUMAN 150 EMLGHKYgVACVAFSPNMKHIVSmGyqH-DMVLNVWD 185 5569*555************99656444.*******9 PP == domain 3 score: 10.7 bits; conditional E-value: 0.048 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 v +l+fs d++++++ + +++vr+W sp|O43379-3|WDR62_HUMAN 201 VIALSFSEDSSYFVTVG-NRHVRFW 224 45899**********9*.******* PP == domain 4 score: 6.9 bits; conditional E-value: 0.74 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ ++ ++++G+ Dg vri+ sp|O43379-3|WDR62_HUMAN 302 CV----SQELIFCGCTDGIVRIF 320 33....5566779999*****97 PP == domain 5 score: 15.4 bits; conditional E-value: 0.0016 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +l f+p ++wl++ +D++++iWd sp|O43379-3|WDR62_HUMAN 364 ALTFDPIHQWLSCVYKDHSIYIWD 387 788*******976699*******9 PP >> tr|Q5JP02|Q5JP02_HUMAN Histone-binding protein RBBP7 (Fragment) OS=Homo sapiens GN=RBBP7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.6 6.5 5.3e+02 30 38 .] 1 9 [. 1 9 [. 0.93 2 ! 16.3 0.2 0.00082 0.067 6 38 .] 25 59 .. 21 59 .. 0.75 3 ! 30.4 0.0 2.8e-08 2.3e-06 3 38 .] 68 105 .. 66 105 .. 0.86 4 ! 23.2 0.2 5.4e-06 0.00044 4 38 .] 113 149 .. 111 149 .. 0.85 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.5 TTSEEEEEE CS WD40 30 dDgtvriWd 38 dD+tv +Wd tr|Q5JP02|Q5JP02_HUMAN 1 DDHTVCLWD 9 6*******9 PP == domain 2 score: 16.3 bits; conditional E-value: 0.00082 EEESSSS.EEEEEEETTSSEEEEEE..TTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGs..dDgtvriWd 38 ++tGHs v ++a++ + l+ Gs dD++++iWd tr|Q5JP02|Q5JP02_HUMAN 25 IFTGHSAvVEDVAWHLLHESLF-GSvaDDQKLMIWD 59 79***7767***5544444488.76458*******9 PP == domain 3 score: 30.4 bits; conditional E-value: 2.8e-08 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + + ++H v++l+f+p++ ++ a+Gs D+tv +Wd tr|Q5JP02|Q5JP02_HUMAN 68 PSHLVDAHtAEVNCLSFNPYSEFIlATGSADKTVALWD 105 6677789*666************6379**********9 PP == domain 4 score: 23.2 bits; conditional E-value: 5.4e-06 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38 l+t++ H++ + + +sp++ ++ s++ D+ + +Wd tr|Q5JP02|Q5JP02_HUMAN 113 LHTFESHKDeIFQVHWSPHNETILaSSGTDRRLNVWD 149 8******556************7525567*******9 PP >> tr|G3V4J7|G3V4J7_HUMAN DDB1- and CUL4-associated factor 5 OS=Homo sapiens GN=DCAF5 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.1 5e-05 0.0041 7 37 .. 49 81 .. 42 82 .. 0.86 2 ? 8.2 0.0 0.31 25 9 35 .. 100 126 .. 92 129 .. 0.81 3 ! 17.6 0.1 0.00032 0.026 7 38 .] 138 170 .. 132 170 .. 0.81 4 ? 6.6 0.1 0.97 78 15 37 .. 285 306 .. 272 307 .. 0.78 5 ! 16.9 0.0 0.00053 0.043 6 38 .] 327 360 .. 324 360 .. 0.91 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 5e-05 EESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 l GH ++v+++ + g+wl+sG+dD+ v +W tr|G3V4J7|G3V4J7_HUMAN 49 LLGHfGCVNAIEfSNNGGQWLVSGGDDRRVLLW 81 569*777*****88888888************* PP == domain 2 score: 8.2 bits; conditional E-value: 0.31 SSSSEEEEEEETTSSEEEEEETTSEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvr 35 Hs++ +laf++ ++ ++sG+ D v tr|G3V4J7|G3V4J7_HUMAN 100 HHSNIFCLAFNSGNTKVFSGGNDEQVI 126 4588****************9887765 PP == domain 3 score: 17.6 bits; conditional E-value: 0.00032 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + +H + v++l++sp ++ + as+sdDg v iWd tr|G3V4J7|G3V4J7_HUMAN 138 F-AHeDAVYGLSVSPVNDNIfASSSDDGRVLIWD 170 4.79777*****9999999735779********9 PP == domain 4 score: 6.6 bits; conditional E-value: 0.97 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++a ++d+ +sGsdD ++++W tr|G3V4J7|G3V4J7_HUMAN 285 CFAGDRDQYI-LSGSDDFNLYMW 306 5556666555.58********** PP == domain 5 score: 16.9 bits; conditional E-value: 0.00053 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH s v+ ++f+p+ +++s++ + ++iW+ tr|G3V4J7|G3V4J7_HUMAN 327 VLKGHrSIVNQVRFNPHTYMICSSGVEKIIKIWS 360 799**7779************99999*******5 PP >> sp|Q96JK2|DCAF5_HUMAN DDB1- and CUL4-associated factor 5 OS=Homo sapiens GN=DCAF5 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.1 5e-05 0.0041 7 37 .. 49 81 .. 42 82 .. 0.86 2 ? 8.1 0.0 0.31 25 9 35 .. 100 126 .. 92 129 .. 0.81 3 ! 17.6 0.1 0.00032 0.026 7 38 .] 139 171 .. 133 171 .. 0.81 4 ? 6.6 0.1 0.97 79 15 37 .. 286 307 .. 273 308 .. 0.78 5 ! 16.9 0.0 0.00053 0.043 6 38 .] 328 361 .. 325 361 .. 0.91 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 5e-05 EESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 l GH ++v+++ + g+wl+sG+dD+ v +W sp|Q96JK2|DCAF5_HUMAN 49 LLGHfGCVNAIEfSNNGGQWLVSGGDDRRVLLW 81 569*777*****88888888************* PP == domain 2 score: 8.1 bits; conditional E-value: 0.31 SSSSEEEEEEETTSSEEEEEETTSEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvr 35 Hs++ +laf++ ++ ++sG+ D v sp|Q96JK2|DCAF5_HUMAN 100 HHSNIFCLAFNSGNTKVFSGGNDEQVI 126 4588****************9887765 PP == domain 3 score: 17.6 bits; conditional E-value: 0.00032 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + +H + v++l++sp ++ + as+sdDg v iWd sp|Q96JK2|DCAF5_HUMAN 139 F-AHeDAVYGLSVSPVNDNIfASSSDDGRVLIWD 171 4.79777*****9999999735779********9 PP == domain 4 score: 6.6 bits; conditional E-value: 0.97 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++a ++d+ +sGsdD ++++W sp|Q96JK2|DCAF5_HUMAN 286 CFAGDRDQYI-LSGSDDFNLYMW 307 5556666555.58********** PP == domain 5 score: 16.9 bits; conditional E-value: 0.00053 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH s v+ ++f+p+ +++s++ + ++iW+ sp|Q96JK2|DCAF5_HUMAN 328 VLKGHrSIVNQVRFNPHTYMICSSGVEKIIKIWS 361 799**7779************99999*******5 PP >> sp|P0C7V8|DC8L2_HUMAN DDB1- and CUL4-associated factor 8-like protein 2 OS=Homo sapiens GN=DCAF8L2 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.1 0.0047 0.38 4 38 .] 221 256 .. 218 256 .. 0.88 2 ? 3.9 0.0 6.7 5.5e+02 19 38 .] 375 395 .. 361 395 .. 0.78 3 ? 10.0 0.1 0.082 6.7 7 38 .] 411 450 .. 406 450 .. 0.77 4 ? 12.5 0.0 0.013 1 4 37 .. 460 497 .. 457 498 .. 0.85 5 ! 17.2 0.0 0.00042 0.034 4 37 .. 505 540 .. 502 541 .. 0.84 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0047 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ l H ++v+ + f++ g+ las++dD +v +Wd sp|P0C7V8|DC8L2_HUMAN 221 QYRLADHvGCVNTVHFNQRGTRLASSGDDLKVIVWD 256 55666898889**************99********9 PP == domain 2 score: 3.9 bits; conditional E-value: 6.7 ETTSSE.EEEEETTSEEEEEE CS WD40 19 spdgaw.lasGsdDgtvriWd 38 +p +++ +a G+ D+ vri+d sp|P0C7V8|DC8L2_HUMAN 375 NPANTYqFAVGGQDQFVRIYD 395 5555555678**********8 PP == domain 3 score: 10.0 bits; conditional E-value: 0.082 EESS...SS.....EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH...ss.....vtslafspdgawlasGsdDgtvriWd 38 +t H ++ +t++ +s+dg+ l+++ D +++++ sp|P0C7V8|DC8L2_HUMAN 411 FTPHhlvNCdfptnITCVVYSHDGTELLASYNDDDIYLFN 450 55443553356788**************998899999886 PP == domain 4 score: 12.5 bits; conditional E-value: 0.013 EEEEESS.SS..EEEEE.EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ss..vtsla.fspdgawlasGsdDgtvriW 37 + ++GH ++ v ++ + p + +++sGsd g++ +W sp|P0C7V8|DC8L2_HUMAN 460 SKRFKGHrNNttVKGVNfYGPRSEFVVSGSDCGHIFFW 497 56799**966689999888999999************* PP == domain 5 score: 17.2 bits; conditional E-value: 0.00042 EEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH..ssvtslafspdgawlasGsdDgtvriW 37 ++ l+G + +++l +p+ + la+++ D+ v+iW sp|P0C7V8|DC8L2_HUMAN 505 IQFLKGSreGTINCLEPHPYLPVLACSGLDHDVKIW 540 56678887444**************9999******* PP >> tr|D6RHX7|D6RHX7_HUMAN Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens GN=MAPKBP1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.0 7e-05 0.0057 9 38 .] 83 120 .. 75 120 .. 0.73 2 ! 15.8 0.0 0.0012 0.098 4 37 .. 127 163 .. 125 163 .. 0.79 3 ! 15.5 0.2 0.0015 0.12 12 37 .. 178 203 .. 168 203 .. 0.90 4 ! 15.3 0.1 0.0017 0.14 5 38 .] 273 300 .. 269 300 .. 0.70 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 7e-05 SS..SS....EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 9 GH..ss....vtslafspdgawlasG..sdDgtvriWd 38 H +s +t+lafspdg++l++G + + vr+Wd tr|D6RHX7|D6RHX7_HUMAN 83 HHilNSsrktITALAFSPDGKYLVTGesGHMPAVRVWD 120 3455334666**************98754588888887 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0012 EEEEESSSS.EEEEEEETTSSEEEEEET..TSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsd..DgtvriW 37 + +l H+ v ++afsp+ ++++s ++ D v +W tr|D6RHX7|D6RHX7_HUMAN 127 VAELQEHKYgVACVAFSPSAKYIVSVGYqhDMIVNVW 163 5678899555************99755223***9999 PP == domain 3 score: 15.5 bits; conditional E-value: 0.0015 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 s vt+++fs d +++++++ ++++++W tr|D6RHX7|D6RHX7_HUMAN 178 SrVTAVSFSEDCSYFVTAG-NRHIKFW 203 349****************.******* PP == domain 4 score: 15.3 bits; conditional E-value: 0.0017 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 rt +H ++ s +++++++G+ Dgtvr+++ tr|D6RHX7|D6RHX7_HUMAN 273 RTTVAH-CI-----SVSQDYIFCGCADGTVRLFN 300 555566.44.....335588889*99******97 PP >> sp|Q8IV35-2|WDR49_HUMAN Isoform 2 of WD repeat-containing protein 49 OS=Homo sapiens GN=WDR49 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 1.2e-05 0.001 2 38 .] 6 45 .. 5 45 .. 0.85 2 ! 16.3 0.1 0.00081 0.066 10 38 .] 107 135 .. 101 135 .. 0.89 3 ? 6.8 0.0 0.83 67 22 38 .] 215 230 .. 179 230 .. 0.82 4 ? 11.0 0.0 0.039 3.2 2 38 .] 235 273 .. 234 273 .. 0.87 5 ? 7.2 0.0 0.63 51 3 36 .. 292 328 .. 290 328 .. 0.84 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 1.2e-05 EEEEEEE.SS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtlt.GH.ss.vtslafspdgawlasGsdDgtvriWd 38 q+++ +t H + ++ +a + + + l++Gs Dgtv+iWd sp|Q8IV35-2|WDR49_HUMAN 6 QKIKQFTgCHgNAeISTMALDANETRLLTGSTDGTVKIWD 45 67777874666558*************************9 PP == domain 2 score: 16.3 bits; conditional E-value: 0.00081 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +++ + af p ++++ +Gs+Dg + +W+ sp|Q8IV35-2|WDR49_HUMAN 107 HhDDILCAAFLPPQTLV-TGSYDGEIVLWN 135 4488************7.7**********8 PP == domain 3 score: 6.8 bits; conditional E-value: 0.83 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 +++++G+ g vr+Wd sp|Q8IV35-2|WDR49_HUMAN 215 ANLVSCGG-SGYVRFWD 230 35566677.*******9 PP == domain 4 score: 11.0 bits; conditional E-value: 0.039 EEEEEEESSSSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla..fspdgawlasGsdDgtvriWd 38 q+l ++ +Hs+v s+ +++ +++l++G+ Dg ++iW+ sp|Q8IV35-2|WDR49_HUMAN 235 QLLAEFLAHSGVGSIImsTDKMNRYLTTGDLDGWLKIWN 273 6788899998898888778888999****99*******8 PP == domain 5 score: 7.2 bits; conditional E-value: 0.63 EEEEEESS.SSEEEEE.EETTSSEEE.EEETTSEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgawla.sGsdDgtvri 36 ++r++ H + ++sl p g++l+ s+s D+++ + sp|Q8IV35-2|WDR49_HUMAN 292 LIRSFQPHeDRISSLEmCEPGGQLLIiSSSADCSICV 328 6789999*777****9999999998648889***976 PP >> sp|Q9NWT1|PK1IP_HUMAN p21-activated protein kinase-interacting protein 1 OS=Homo sapiens GN=PAK1IP1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.3 0.011 0.85 9 38 .] 40 68 .. 30 68 .. 0.71 2 ! 20.3 0.3 4.4e-05 0.0036 9 38 .] 80 109 .. 73 109 .. 0.84 3 ! 23.1 0.1 5.8e-06 0.00047 1 38 [] 113 151 .. 113 151 .. 0.87 4 ? 11.8 0.0 0.022 1.8 3 38 .] 237 275 .. 235 275 .. 0.66 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.011 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H s +++ +++++++Gs+D t++i+d sp|Q9NWT1|PK1IP_HUMAN 40 AHtASLSAV--AVNSRFVVTGSKDETIHIYD 68 455445444..4499**************98 PP == domain 2 score: 20.3 bits; conditional E-value: 4.4e-05 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 Hs+ +t+l+f + +++ sG +Dg + iWd sp|Q9NWT1|PK1IP_HUMAN 80 HHSGtITCLKFYGNRHLI-SGAEDGLICIWD 109 46445****999999997.8**********9 PP == domain 3 score: 23.1 bits; conditional E-value: 5.8e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++cl+++++H + vt l+ +p+g++ +s + D+t+r W+ sp|Q9NWT1|PK1IP_HUMAN 113 WECLKSIKAHkGQVTFLSIHPSGKLALSVGTDKTLRTWN 151 68********555************776555*******8 PP == domain 4 score: 11.8 bits; conditional E-value: 0.022 EEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 cl ++++H + v ++ p+++ ++s+s Dg +++W+ sp|Q9NWT1|PK1IP_HUMAN 237 CLCEFKAHeNRVKDMFsfEIPEHHVIVSASSDGFIKMWK 275 8999999988876553332222222677766*******6 PP >> sp|Q96MR6|WDR65_HUMAN WD repeat-containing protein 65 OS=Homo sapiens GN=WDR65 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 2.2 1.8e+02 12 31 .. 340 359 .. 330 363 .. 0.78 2 ! 15.8 0.0 0.0011 0.092 10 38 .] 388 417 .. 382 417 .. 0.90 3 ! 17.9 0.2 0.00025 0.02 2 38 .] 503 540 .. 502 540 .. 0.90 4 ? 6.5 0.1 1 83 14 35 .. 558 579 .. 551 579 .. 0.86 5 ? 6.4 0.0 1.1 90 5 37 .. 632 665 .. 628 666 .. 0.88 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 2.2 SEEEEEEETTSSEEEEE.ETT CS WD40 12 svtslafspdgawlasG.sdD 31 +v +l+fsp+ l+++ s + sp|Q96MR6|WDR65_HUMAN 340 DVLCLCFSPSEETLVAStS-K 359 599**********987634.4 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0011 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H ++t+la++ ++++a++s D+++r+W+ sp|Q96MR6|WDR65_HUMAN 388 HsAPITGLATCIRKPLIATCSLDRSIRLWN 417 856699999999*****************8 PP == domain 3 score: 17.9 bits; conditional E-value: 0.00025 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +l+GH + ++s+ ++ d + l+sG+ Dg v+ W+ sp|Q96MR6|WDR65_HUMAN 503 ENISSLKGHtGKIRSIVWNADDSKLISGGTDGAVYEWN 540 57899****666****************99****9997 PP == domain 4 score: 6.5 bits; conditional E-value: 1 EEEEEETTSSEE.EEEETTSEEE CS WD40 14 tslafspdgawl.asGsdDgtvr 35 +++ +spd + + a Gs D+t++ sp|Q96MR6|WDR65_HUMAN 558 NCVTVSPDAKIIfAVGS-DHTLK 579 7999*******835789.***97 PP == domain 5 score: 6.4 bits; conditional E-value: 1.1 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++ +H +++t + d ++l+++ +Dg + W sp|Q96MR6|WDR65_HUMAN 632 NEYQAHaGPITKMLLTFDDQFLLTAAEDGCLFTW 665 6799**999****************99**99877 PP >> tr|F8W0U9|F8W0U9_HUMAN NACHT and WD repeat domain-containing protein 1 OS=Homo sapiens GN=NWD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.0 0.095 7.7 6 38 .] 863 896 .. 858 896 .. 0.87 2 ! 17.5 0.1 0.00034 0.027 4 38 .] 903 938 .. 900 938 .. 0.87 3 ? 4.7 0.1 3.8 3.1e+02 13 38 .] 1003 1028 .. 988 1028 .. 0.76 4 ? 4.3 0.0 5.2 4.2e+02 13 38 .] 1131 1156 .. 1124 1156 .. 0.80 5 ! 13.5 0.0 0.0063 0.51 7 38 .] 1342 1374 .. 1337 1374 .. 0.93 6 ? 12.5 0.2 0.013 1 12 38 .] 1392 1419 .. 1380 1419 .. 0.83 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.095 EEE.SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tlt.GHssvtslafspdgawlasGsdDgtvriWd 38 tl+ H+++t++a+ + ++l+ G+ Dg +Wd tr|F8W0U9|F8W0U9_HUMAN 863 TLSgCHKGITAMAWGVEEKLLVIGTQDGIMAVWD 896 56635699****99999999*************9 PP == domain 2 score: 17.5 bits; conditional E-value: 0.00034 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ ltGH + v++++ g++ a s+s+D t+++W+ tr|F8W0U9|F8W0U9_HUMAN 903 IHMLTGHtGEVRCVKIFAKGTL-AnSASKDYTLHLWN 938 7889***777****99999999.87789********8 PP == domain 3 score: 4.7 bits; conditional E-value: 3.8 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++a+ ++a l++ s+Dg v +W+ tr|F8W0U9|F8W0U9_HUMAN 1003 WMCMAVLASQATLLTVSRDGVVSLWS 1028 4588888888899999*********5 PP == domain 4 score: 4.3 bits; conditional E-value: 5.2 E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 v.tslafspdgawlasGsdDgtvriWd 38 v t++ f +++++++Gs D + +Wd tr|F8W0U9|F8W0U9_HUMAN 1131 VeTAV-FGTENNLIITGSLDALIQVWD 1156 64444.8889999*************9 PP == domain 5 score: 13.5 bits; conditional E-value: 0.0063 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++H s v ++ +s+ ++++sGs+D + +Wd tr|F8W0U9|F8W0U9_HUMAN 1342 LETHrSRVACVEVSHKEQLVVSGSEDALLCLWD 1374 679*899*************************9 PP == domain 6 score: 12.5 bits; conditional E-value: 0.013 S.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriWd 38 v + +fs+d +++ G +D+++ +W+ tr|F8W0U9|F8W0U9_HUMAN 1392 RgVQCACFSKDDKYVYVGLKDRSILVWS 1419 2499**************9********5 PP >> tr|H7C5J5|H7C5J5_HUMAN Guanine nucleotide-binding protein subunit beta-4 (Fragment) OS=Homo sapiens GN=GNB4 PE=4 SV= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 0.0029 0.23 12 38 .] 22 48 .. 11 48 .. 0.88 2 ! 21.5 0.2 1.9e-05 0.0016 4 38 .] 59 93 .. 56 93 .. 0.90 3 ! 23.7 0.1 3.6e-06 0.00029 2 38 .] 98 135 .. 97 135 .. 0.92 4 ? 9.1 0.0 0.16 13 3 17 .. 141 156 .. 139 161 .. 0.84 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.0029 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ tr|H7C5J5|H7C5J5_HUMAN 22 WVMTCAYAPSGNYVACGGLDNICSIYN 48 487889*******************97 PP == domain 2 score: 21.5 bits; conditional E-value: 1.9e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + ++++f +d++ ++s++ D t+ +Wd tr|H7C5J5|H7C5J5_HUMAN 59 SRELPGHtGYLSCCRFLDDSQIVTSSG-DTTCALWD 93 57899**666*************9989.*******9 PP == domain 3 score: 23.7 bits; conditional E-value: 3.6e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+++t+tGH ++v sl+ spd + ++sG D + ++Wd tr|H7C5J5|H7C5J5_HUMAN 98 QQTTTFTGHsGDVMSLSLSPDMRTFVSGACDASSKLWD 135 67889****777****************77*******9 PP == domain 4 score: 9.1 bits; conditional E-value: 0.16 EEEEEESS.SSEEEEE CS WD40 3 clrtltGH.ssvtsla 17 c +++tGH s++++++ tr|H7C5J5|H7C5J5_HUMAN 141 CRQSFTGHvSDINAVS 156 899*****999*9995 PP >> tr|H3BRY3|H3BRY3_HUMAN Coronin OS=Homo sapiens GN=CORO1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.2 1.7e-06 0.00014 7 37 .. 77 109 .. 72 110 .. 0.86 2 ! 16.7 0.1 0.00059 0.048 2 38 .] 122 160 .. 121 160 .. 0.79 3 ! 18.0 0.0 0.00024 0.019 9 36 .. 174 202 .. 167 204 .. 0.89 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 1.7e-06 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH +v ++a++p+++ + asGs+D+tv++W tr|H3BRY3|H3BRY3_HUMAN 77 VCGHtAPVLDIAWCPHNDNViASGSEDCTVMVW 109 459*888************73699********* PP == domain 2 score: 16.7 bits; conditional E-value: 0.00059 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v +a++ + l++G+ D+ +++Wd tr|H3BRY3|H3BRY3_HUMAN 122 EPVVTLEGHtKRVGIVAWHTTAQNvlLSAGC-DNVIMVWD 160 68899****9889888777777774344677.*******9 PP == domain 3 score: 18.0 bits; conditional E-value: 0.00024 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 H + ++s+++s+dg +++++++D+ vri tr|H3BRY3|H3BRY3_HUMAN 174 VHpDTIYSVDWSRDGGLICTSCRDKRVRI 202 68777**************9999*****9 PP >> tr|H0YMF9|H0YMF9_HUMAN WD repeat-containing protein 61 OS=Homo sapiens GN=WDR61 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.1 0.0044 0.36 9 38 .] 14 48 .. 6 48 .. 0.79 2 ! 20.0 0.4 5.4e-05 0.0044 3 38 .] 56 92 .. 54 92 .. 0.91 3 ? 10.8 0.0 0.044 3.6 14 29 .. 110 125 .. 96 132 .. 0.80 4 ! 21.1 0.0 2.5e-05 0.002 11 38 .] 149 176 .. 138 176 .. 0.84 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.0044 SS.SSEEEEEEETTSSE..........EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..........lasGsdDgtvriWd 38 +H + ++s+a w +++Gs D v++W+ tr|H0YMF9|H0YMF9_HUMAN 14 AHdDAIWSVA------WgtnkkensetVVTGSLDDLVKVWK 48 89555****5......5555555999999***********6 PP == domain 2 score: 20.0 bits; conditional E-value: 5.4e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++l+GH +v s++ s+ + as+s D ++r+Wd tr|H0YMF9|H0YMF9_HUMAN 56 LQWSLEGHqLGVVSVDISHTLPIAASSSLDAHIRLWD 92 6899****76699**********99999********9 PP == domain 3 score: 10.8 bits; conditional E-value: 0.044 EEEEEETTSSEEEEEE CS WD40 14 tslafspdgawlasGs 29 + lafspd+++la+G+ tr|H0YMF9|H0YMF9_HUMAN 110 WTLAFSPDSQYLATGT 125 7899**********95 PP == domain 4 score: 21.1 bits; conditional E-value: 2.5e-05 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 +++ s+a+spdg++lasG Dg + i+d tr|H0YMF9|H0YMF9_HUMAN 149 KFILSIAYSPDGKYLASGAIDGIINIFD 176 5799**********************98 PP >> tr|B4DGZ9|B4DGZ9_HUMAN DNA excision repair protein ERCC-8 OS=Homo sapiens GN=ERCC8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.3 0.1 1.4e-08 1.2e-06 1 38 [] 23 62 .. 23 62 .. 0.92 2 ! 18.6 0.1 0.00016 0.013 8 38 .] 89 120 .. 68 120 .. 0.87 3 ! 15.3 0.0 0.0017 0.13 2 37 .. 172 208 .. 171 209 .. 0.87 Alignments for each domain: == domain 1 score: 31.3 bits; conditional E-value: 1.4e-08 TEEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 g+c ++l GH + + ++++sp +++ a++s D v++Wd tr|B4DGZ9|B4DGZ9_HUMAN 23 GSCSHILQGHrQEILAVSWSPRYDYIlATASADSRVKLWD 62 68********999************6268899*******9 PP == domain 2 score: 18.6 bits; conditional E-value: 0.00016 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 t+H++ v++l+f +dg l++ + D+ r+W+ tr|B4DGZ9|B4DGZ9_HUMAN 89 TAHNGkVNGLCFTSDGLHLLTVGTDNRMRLWN 120 689556************997666*******8 PP == domain 3 score: 15.3 bits; conditional E-value: 0.0017 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++ l+GH + v ++ f+++ + l sGs+D+++ W tr|B4DGZ9|B4DGZ9_HUMAN 172 EQITMLKGHyKTVDCCVFQSNFQELYSGSRDCNILAW 208 667889*******77779999999*********9877 PP >> tr|E9PDU5|E9PDU5_HUMAN WD repeat-containing protein 6 OS=Homo sapiens GN=WDR6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 0.00047 0.038 6 38 .] 153 186 .. 149 186 .. 0.88 2 ? 8.0 0.3 0.35 28 2 38 .] 198 233 .. 197 233 .. 0.77 3 ! 21.1 0.1 2.4e-05 0.002 2 37 .. 237 274 .. 236 275 .. 0.89 4 ? 12.0 0.2 0.018 1.5 2 37 .. 920 959 .. 919 960 .. 0.76 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 0.00047 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++GH + + s+++ ++ +la++s+D++vriW+ tr|E9PDU5|E9PDU5_HUMAN 153 RISGHvGIIFSMSYLESKGLLATASEDRSVRIWK 186 568**6668***99999999*************6 PP == domain 2 score: 8.0 bits; conditional E-value: 0.35 EEEEEEESSSS.EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgaw....lasGsdDgtvriWd 38 q+++++ GHs v+ + ++ l+s+++D+ + +W+ tr|E9PDU5|E9PDU5_HUMAN 198 QNIGHCFGHSArVWQV------KLlenyLISAGEDCVCLVWS 233 5677777994459999......775666789999*******5 PP == domain 3 score: 21.1 bits; conditional E-value: 2.4e-05 EEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss..vtslafspdgawlasGsdDgtvriW 37 + l+ ++GH++ ++++a + +aw+++G+dD +r+W tr|E9PDU5|E9PDU5_HUMAN 237 EILQAFRGHQGrgIRAIAAHERQAWVITGGDDSGIRLW 274 67889****4458************************* PP == domain 4 score: 12.0 bits; conditional E-value: 0.018 EEEEEEESS.SSEEEEE..EETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgaw.lasGsdDgtvriW 37 ++ tl +H ++++sl ++g+ +asGs+Dg+++++ tr|E9PDU5|E9PDU5_HUMAN 920 TPSLTLQAHsCGINSLHtlPTREGHHlVASGSEDGSLHVF 959 5678999**777****887555555535799******986 PP >> tr|U3KQC1|U3KQC1_HUMAN WD repeat-containing protein 18 (Fragment) OS=Homo sapiens GN=WDR18 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.6 2.6e-05 0.0021 2 38 .] 74 111 .. 73 111 .. 0.93 2 ! 13.0 0.2 0.0089 0.72 4 37 .. 127 163 .. 125 164 .. 0.83 3 ! 36.0 0.3 5e-10 4e-08 5 38 .] 225 259 .. 221 259 .. 0.95 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 2.6e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l +l+ H ++v++l+f d++ ++sG++D+ v +W+ tr|U3KQC1|U3KQC1_HUMAN 74 NLLVILSRHyQDVSCLQFTGDSSHFISGGKDCLVLVWS 111 67788999*99**************************5 PP == domain 2 score: 13.0 bits; conditional E-value: 0.0089 EEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw..lasGsdDgtvriW 37 ++++ H ++t+l g++ +a++s D+tv++W tr|U3KQC1|U3KQC1_HUMAN 127 RHVWSHHaLPITDLHCGFGGPLarVATSSLDQTVKLW 163 5778888777****98888888778999********* PP == domain 3 score: 36.0 bits; conditional E-value: 5e-10 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++GH + vt+l++s dg+ l+sGs D tvr+Wd tr|U3KQC1|U3KQC1_HUMAN 225 KVFKGHrNQVTCLSVSTDGSVLLSGSHDETVRLWD 259 689***999****************99*******9 PP >> tr|C0H5X6|C0H5X6_HUMAN PEX7 protein OS=Homo sapiens GN=PEX7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.6 0.013 1 12 38 .] 69 96 .. 58 96 .. 0.75 2 ! 26.4 0.0 5.3e-07 4.3e-05 3 38 .] 103 141 .. 101 141 .. 0.87 3 ! 19.8 0.3 6.4e-05 0.0052 1 38 [] 145 184 .. 145 184 .. 0.74 4 ? 11.4 0.1 0.028 2.3 7 38 .] 194 227 .. 190 227 .. 0.80 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 SEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 12 svtslafspdgawla.sGsdDgtvriWd 38 + ++ +s ++ ++ ++s Dg++ +Wd tr|C0H5X6|C0H5X6_HUMAN 69 GLFDVTWSENNEHVLiTCSGDGSLQLWD 96 46789899999996448877*******9 PP == domain 2 score: 26.4 bits; conditional E-value: 5.3e-07 EEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 +l++++ H + v+s+ +w ++sGs+D+tv++Wd tr|C0H5X6|C0H5X6_HUMAN 103 PLQVYKEHaQEVYSV------DWsqtrgeqlVVSGSWDQTVKLWD 141 7899****888****......777777779788***********9 PP == domain 3 score: 19.8 bits; conditional E-value: 6.4e-05 TEEEEEEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 g+ l t++GH s ++s w +as+s D+t+riWd tr|C0H5X6|C0H5X6_HUMAN 145 GKSLCTFRGHeSIIYST------IWsphipgcFASASGDQTLRIWD 184 57789*****5558888......555555556677766*******9 PP == domain 4 score: 11.4 bits; conditional E-value: 0.028 EESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + +H + s+++++++ l++G D+++r Wd tr|C0H5X6|C0H5X6_HUMAN 194 IPAHqAEILSCDWCKYNENlLVTGAVDCSLRGWD 227 4689666****888888884479*9********8 PP >> sp|Q9H6Y2|WDR55_HUMAN WD repeat-containing protein 55 OS=Homo sapiens GN=WDR55 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.0 0.21 17 15 37 .. 43 65 .. 37 66 .. 0.91 2 ? 11.3 0.1 0.031 2.5 8 36 .. 80 110 .. 74 112 .. 0.86 3 ? 6.7 0.0 0.9 73 8 38 .] 124 154 .. 116 154 .. 0.80 4 ? 5.7 0.0 1.8 1.5e+02 6 38 .] 163 196 .. 158 196 .. 0.81 5 ! 18.5 0.0 0.00017 0.014 5 38 .] 288 323 .. 284 323 .. 0.82 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.21 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 +laf+p ++la+G+ Dg v ++ sp|Q9H6Y2|WDR55_HUMAN 43 GLAFHPARDLLAAGDVDGDVFVF 65 799***********99***9886 PP == domain 2 score: 11.3 bits; conditional E-value: 0.031 ESS..SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 8 tGH..ssvtslafspdgawlasGsdDgtvri 36 +GH + +++afs dg+ l++ s+D+ +++ sp|Q9H6Y2|WDR55_HUMAN 80 SGHhlKACRAVAFSEDGQKLITVSKDKAIHV 110 57868789*******************9987 PP == domain 3 score: 6.7 bits; conditional E-value: 0.9 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++H +++sl d + la+G+d g + +Wd sp|Q9H6Y2|WDR55_HUMAN 124 KAHgAPINSL-LLVDENVLATGDDTGGICLWD 154 6897789999.666666689***9*******9 PP == domain 4 score: 5.7 bits; conditional E-value: 1.8 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H + ++a +p +++l+++s Dg + i++ sp|Q9H6Y2|WDR55_HUMAN 163 DMRQHeEYIADMALDPAKKLLLTASGDGCLGIFN 196 56789666999**********99877**987765 PP == domain 5 score: 18.5 bits; conditional E-value: 0.00017 EEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 ++ H +v la s+ g++las++ D+ +++Wd sp|Q9H6Y2|WDR55_HUMAN 288 GSVGQHtgEPVEELALSHCGRFLASSGHDQRLKFWD 323 5666785344**************8777*******9 PP >> sp|Q9BUR4|WAP53_HUMAN Telomerase Cajal body protein 1 OS=Homo sapiens GN=WRAP53 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.0 0.13 10 11 38 .] 170 197 .. 155 197 .. 0.84 2 ! 15.2 0.0 0.0019 0.15 14 37 .. 281 303 .. 263 304 .. 0.83 3 ? 7.5 0.0 0.51 41 9 32 .. 323 347 .. 315 355 .. 0.79 4 ! 22.0 0.1 1.3e-05 0.001 2 38 .] 358 396 .. 357 396 .. 0.87 5 ? 11.2 0.1 0.033 2.7 15 38 .] 420 441 .. 405 441 .. 0.84 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.13 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++ ++++ pdg+ +++ s D+ +ri++ sp|Q9BUR4|WAP53_HUMAN 170 NFLKGCKWAPDGSCILTNSADNILRIYN 197 4467899*********9899******98 PP == domain 2 score: 15.2 bits; conditional E-value: 0.0019 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 +sl+fspdg+ l++G ++tvr++ sp|Q9BUR4|WAP53_HUMAN 281 HSLCFSPDGSQLFCGF-NRTVRVF 303 69***********999.*****97 PP == domain 3 score: 7.5 bits; conditional E-value: 0.51 SSSS.EEEEEEETTSSEEEEEETTS CS WD40 9 GHss.vtslafspdgawlasGsdDg 32 G+s+ ++++afsp +++ a+Gs+ + sp|Q9BUR4|WAP53_HUMAN 323 GQSGiISCIAFSPAQPLYACGSYGR 347 675557***********99999555 PP == domain 4 score: 22.0 bits; conditional E-value: 1.3e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs.dDgtvriWd 38 ++l l GH +++t+l+f+pdg+ ++sG +D + Wd sp|Q9BUR4|WAP53_HUMAN 358 SPLALLGGHqGGITHLCFHPDGNRFFSGArKDAELLCWD 396 6788899**888****************74699999998 PP == domain 5 score: 11.2 bits; conditional E-value: 0.033 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 + +p g++l+sGs g v +Wd sp|Q9BUR4|WAP53_HUMAN 420 D--LDPTGQFLVSGSTSGAVSVWD 441 3..59******************9 PP >> tr|B3KSY4|B3KSY4_HUMAN Coronin OS=Homo sapiens GN=CORO7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.034 2.7 12 37 .. 326 352 .. 318 353 .. 0.85 2 ! 23.3 0.0 4.9e-06 0.0004 4 38 .] 367 403 .. 364 403 .. 0.85 3 ! 24.4 0.0 2.3e-06 0.00019 7 37 .. 413 444 .. 409 445 .. 0.90 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.034 SEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriW 37 vt+la++p + la +++D +r+W tr|B3KSY4|B3KSY4_HUMAN 326 AVTDLAWDPFDPHrLAVAGEDARIRLW 352 49***********9887888******* PP == domain 2 score: 23.3 bits; conditional E-value: 4.9e-06 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ltGH ++sl+f+p a ++ s+s+D tvriWd tr|B3KSY4|B3KSY4_HUMAN 367 ETVLTGHtEKICSLRFHPLAANVLaSSSYDLTVRIWD 403 5789***666************7527789*******9 PP == domain 3 score: 24.4 bits; conditional E-value: 2.3e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH + + sla+spdg+ la+ ++Dg vr++ tr|B3KSY4|B3KSY4_HUMAN 413 LQGHqDQIFSLAWSPDGQQLATVCKDGRVRVY 444 78**666***************9*******98 PP >> sp|P31146|COR1A_HUMAN Coronin-1A OS=Homo sapiens GN=CORO1A PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.2 2.1e-06 0.00017 7 37 .. 77 109 .. 72 110 .. 0.86 2 ! 16.4 0.1 0.00075 0.06 2 38 .] 122 160 .. 121 160 .. 0.79 3 ! 17.7 0.0 0.00029 0.024 9 36 .. 174 202 .. 167 204 .. 0.89 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 2.1e-06 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH +v ++a++p+++ + asGs+D+tv++W sp|P31146|COR1A_HUMAN 77 VCGHtAPVLDIAWCPHNDNViASGSEDCTVMVW 109 459*888************73699********* PP == domain 2 score: 16.4 bits; conditional E-value: 0.00075 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v +a++ + l++G+ D+ +++Wd sp|P31146|COR1A_HUMAN 122 EPVVTLEGHtKRVGIVAWHTTAQNvlLSAGC-DNVIMVWD 160 68899****9889888777777774344677.*******9 PP == domain 3 score: 17.7 bits; conditional E-value: 0.00029 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 H + ++s+++s+dg +++++++D+ vri sp|P31146|COR1A_HUMAN 174 VHpDTIYSVDWSRDGGLICTSCRDKRVRI 202 68777**************9999*****9 PP >> tr|E9PBV1|E9PBV1_HUMAN NACHT and WD repeat domain-containing protein 1 OS=Homo sapiens GN=NWD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.083 6.7 6 38 .] 657 690 .. 652 690 .. 0.87 2 ! 17.7 0.1 0.0003 0.024 4 38 .] 697 732 .. 694 732 .. 0.87 3 ? 4.9 0.1 3.4 2.7e+02 13 38 .] 797 822 .. 782 822 .. 0.76 4 ! 13.7 0.0 0.0056 0.45 7 38 .] 1178 1210 .. 1173 1210 .. 0.93 5 ? 12.7 0.2 0.011 0.92 12 38 .] 1228 1255 .. 1216 1255 .. 0.83 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.083 EEE.SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tlt.GHssvtslafspdgawlasGsdDgtvriWd 38 tl+ H+++t++a+ + ++l+ G+ Dg +Wd tr|E9PBV1|E9PBV1_HUMAN 657 TLSgCHKGITAMAWGVEEKLLVIGTQDGIMAVWD 690 56635699****99999999*************9 PP == domain 2 score: 17.7 bits; conditional E-value: 0.0003 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ ltGH + v++++ g++ a s+s+D t+++W+ tr|E9PBV1|E9PBV1_HUMAN 697 IHMLTGHtGEVRCVKIFAKGTL-AnSASKDYTLHLWN 732 788****777****99999999.87789********8 PP == domain 3 score: 4.9 bits; conditional E-value: 3.4 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++a+ ++a l++ s+Dg v +W+ tr|E9PBV1|E9PBV1_HUMAN 797 WMCMAVLASQATLLTVSRDGVVSLWS 822 4588888888899999*********5 PP == domain 4 score: 13.7 bits; conditional E-value: 0.0056 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++H s v ++ +s+ ++++sGs+D + +Wd tr|E9PBV1|E9PBV1_HUMAN 1178 LETHrSRVACVEVSHKEQLVVSGSEDALLCLWD 1210 679*899*************************9 PP == domain 5 score: 12.7 bits; conditional E-value: 0.011 S.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriWd 38 v + +fs+d +++ G +D+++ +W+ tr|E9PBV1|E9PBV1_HUMAN 1228 RgVQCACFSKDDKYVYVGLKDRSILVWS 1255 2499**************9********5 PP >> tr|C9J2Y8|C9J2Y8_HUMAN NACHT and WD repeat domain-containing protein 1 OS=Homo sapiens GN=NWD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.088 7.1 6 38 .] 728 761 .. 723 761 .. 0.87 2 ! 17.6 0.1 0.00031 0.025 4 38 .] 768 803 .. 765 803 .. 0.87 3 ? 4.8 0.1 3.6 2.9e+02 13 38 .] 868 893 .. 853 893 .. 0.76 4 ! 13.6 0.0 0.0059 0.48 7 38 .] 1249 1281 .. 1244 1281 .. 0.93 5 ? 12.6 0.2 0.012 0.98 12 38 .] 1299 1326 .. 1287 1326 .. 0.83 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.088 EEE.SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tlt.GHssvtslafspdgawlasGsdDgtvriWd 38 tl+ H+++t++a+ + ++l+ G+ Dg +Wd tr|C9J2Y8|C9J2Y8_HUMAN 728 TLSgCHKGITAMAWGVEEKLLVIGTQDGIMAVWD 761 56635699****99999999*************9 PP == domain 2 score: 17.6 bits; conditional E-value: 0.00031 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ ltGH + v++++ g++ a s+s+D t+++W+ tr|C9J2Y8|C9J2Y8_HUMAN 768 IHMLTGHtGEVRCVKIFAKGTL-AnSASKDYTLHLWN 803 7889***777****99999999.87789********8 PP == domain 3 score: 4.8 bits; conditional E-value: 3.6 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++a+ ++a l++ s+Dg v +W+ tr|C9J2Y8|C9J2Y8_HUMAN 868 WMCMAVLASQATLLTVSRDGVVSLWS 893 4588888888899999*********5 PP == domain 4 score: 13.6 bits; conditional E-value: 0.0059 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++H s v ++ +s+ ++++sGs+D + +Wd tr|C9J2Y8|C9J2Y8_HUMAN 1249 LETHrSRVACVEVSHKEQLVVSGSEDALLCLWD 1281 679*899*************************9 PP == domain 5 score: 12.6 bits; conditional E-value: 0.012 S.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriWd 38 v + +fs+d +++ G +D+++ +W+ tr|C9J2Y8|C9J2Y8_HUMAN 1299 RgVQCACFSKDDKYVYVGLKDRSILVWS 1326 2499**************9********5 PP >> tr|B4DTL1|B4DTL1_HUMAN WD repeat and SOCS box-containing protein 1 OS=Homo sapiens GN=WSB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.1 0.041 3.3 17 38 .] 124 156 .. 95 156 .. 0.71 2 ! 27.1 0.0 3.3e-07 2.6e-05 2 38 .] 161 199 .. 160 199 .. 0.83 3 ! 22.6 0.0 8.6e-06 0.0007 2 36 .. 205 240 .. 204 240 .. 0.85 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.041 E...........EETTSSEEEEEETTSEEEEEE CS WD40 17 a...........fspdgawlasGsdDgtvriWd 38 + f +d+ +la+G +g ++iWd tr|B4DTL1|B4DTL1_HUMAN 124 SrcvniewhrfrFGQDQLLLATGLNNGRIKIWD 156 0555566666668899999****77*******9 PP == domain 2 score: 27.1 bits; conditional E-value: 3.3e-07 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 ++l l H+ v++l f pdg+++ +s+s+D+t+r+Wd tr|B4DTL1|B4DTL1_HUMAN 161 KLLLNLVDHTEvVRDLTFAPDGSLIlVSASRDKTLRVWD 199 6677788896657***********62589*********9 PP == domain 3 score: 22.6 bits; conditional E-value: 8.6e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 + +++l+GH ++v+s+afspd+++l+s + + vr+ tr|B4DTL1|B4DTL1_HUMAN 205 NMMKVLRGHqNWVYSCAFSPDSSMLCSVGASKAVRV 240 66899****999*************87666777775 PP >> sp|Q04727-2|TLE4_HUMAN Isoform 2 of Transducin-like enhancer protein 4 OS=Homo sapiens GN=TLE4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 0.035 2.9 10 38 .] 417 445 .. 409 445 .. 0.83 2 ? 7.3 0.0 0.56 45 12 38 .] 466 492 .. 448 492 .. 0.87 3 ! 13.0 0.2 0.0091 0.74 14 38 .] 512 536 .. 502 536 .. 0.85 4 ! 16.2 0.8 0.00086 0.07 3 38 .] 542 578 .. 540 578 .. 0.86 5 ? 7.1 0.0 0.68 55 7 34 .. 585 615 .. 580 617 .. 0.76 6 ? 9.7 0.1 0.1 8.2 10 37 .. 631 659 .. 625 660 .. 0.85 7 ? 6.6 0.1 0.96 78 11 33 .. 674 696 .. 666 701 .. 0.82 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.035 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H+ v+++ s + + +G+ +g v++Wd sp|Q04727-2|TLE4_HUMAN 417 HGEvVCAVTISNPTRHVYTGG-KGCVKVWD 445 7555799999999999*****.*******9 PP == domain 2 score: 7.3 bits; conditional E-value: 0.56 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04727-2|TLE4_HUMAN 466 YIRSCRLLPDGRTLIVGGEASTLSIWD 492 3889999*******************9 PP == domain 3 score: 13.0 bits; conditional E-value: 0.0091 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd++ +s++ Dg++ +Wd sp|Q04727-2|TLE4_HUMAN 512 YALAISPDSKVCFSCCSDGNIAVWD 536 6899*******887755*******9 PP == domain 4 score: 16.2 bits; conditional E-value: 0.00086 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s dg+ l +G+ D+tvr Wd sp|Q04727-2|TLE4_HUMAN 542 LVRQFQGHtDGASCIDISNDGTKLWTGGLDNTVRSWD 578 6899****777999999999999647999*******9 PP == domain 5 score: 7.1 bits; conditional E-value: 0.68 EESS..SS.EEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH..ss.vtslafspdgawlasGsdDgtv 34 l H +s + sl ++p g wla G+++ +v sp|Q04727-2|TLE4_HUMAN 585 LQQHdfTSqIFSLGYCPTGEWLAVGMENSNV 615 566753226****************988777 PP == domain 6 score: 9.7 bits; conditional E-value: 0.1 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W sp|Q04727-2|TLE4_HUMAN 631 HeSCVLSLKFAHCGKWFVSTGKDNLLNAW 659 7778**************99999987766 PP == domain 7 score: 6.6 bits; conditional E-value: 0.96 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ sp|Q04727-2|TLE4_HUMAN 674 SSVLSCDISVDDKYIVTGSGDKK 696 45999*************87986 PP >> tr|G8JLG4|G8JLG4_HUMAN Transducin-like enhancer protein 4 OS=Homo sapiens GN=TLE4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 0.035 2.9 10 38 .] 417 445 .. 409 445 .. 0.83 2 ? 7.3 0.0 0.56 45 12 38 .] 466 492 .. 448 492 .. 0.87 3 ! 13.0 0.2 0.0091 0.74 14 38 .] 512 536 .. 502 536 .. 0.85 4 ! 16.2 0.8 0.00086 0.07 3 38 .] 542 578 .. 540 578 .. 0.86 5 ? 7.1 0.0 0.68 55 7 34 .. 585 615 .. 580 617 .. 0.76 6 ? 9.7 0.1 0.1 8.2 10 37 .. 631 659 .. 625 660 .. 0.85 7 ? 6.6 0.1 0.96 78 11 33 .. 674 696 .. 666 701 .. 0.82 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.035 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H+ v+++ s + + +G+ +g v++Wd tr|G8JLG4|G8JLG4_HUMAN 417 HGEvVCAVTISNPTRHVYTGG-KGCVKVWD 445 7555799999999999*****.*******9 PP == domain 2 score: 7.3 bits; conditional E-value: 0.56 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|G8JLG4|G8JLG4_HUMAN 466 YIRSCRLLPDGRTLIVGGEASTLSIWD 492 3889999*******************9 PP == domain 3 score: 13.0 bits; conditional E-value: 0.0091 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd++ +s++ Dg++ +Wd tr|G8JLG4|G8JLG4_HUMAN 512 YALAISPDSKVCFSCCSDGNIAVWD 536 6899*******887755*******9 PP == domain 4 score: 16.2 bits; conditional E-value: 0.00086 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s dg+ l +G+ D+tvr Wd tr|G8JLG4|G8JLG4_HUMAN 542 LVRQFQGHtDGASCIDISNDGTKLWTGGLDNTVRSWD 578 6899****777999999999999647999*******9 PP == domain 5 score: 7.1 bits; conditional E-value: 0.68 EESS..SS.EEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH..ss.vtslafspdgawlasGsdDgtv 34 l H +s + sl ++p g wla G+++ +v tr|G8JLG4|G8JLG4_HUMAN 585 LQQHdfTSqIFSLGYCPTGEWLAVGMENSNV 615 566753226****************988777 PP == domain 6 score: 9.7 bits; conditional E-value: 0.1 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W tr|G8JLG4|G8JLG4_HUMAN 631 HeSCVLSLKFAHCGKWFVSTGKDNLLNAW 659 7778**************99999987766 PP == domain 7 score: 6.6 bits; conditional E-value: 0.96 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|G8JLG4|G8JLG4_HUMAN 674 SSVLSCDISVDDKYIVTGSGDKK 696 45999*************87986 PP >> sp|Q58WW2|DCAF6_HUMAN DDB1- and CUL4-associated factor 6 OS=Homo sapiens GN=DCAF6 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.1 0.00065 0.053 5 35 .. 45 76 .. 41 77 .. 0.86 2 ? 7.3 0.0 0.55 45 8 38 .] 138 170 .. 132 170 .. 0.60 3 ? 5.4 0.0 2.3 1.8e+02 24 38 .] 206 220 .. 192 220 .. 0.78 4 ? 4.7 0.0 3.7 3e+02 9 32 .. 247 275 .. 241 281 .. 0.71 5 ? 10.4 0.1 0.06 4.8 6 38 .] 712 747 .. 709 747 .. 0.77 6 ! 14.8 0.0 0.0024 0.19 11 38 .] 761 789 .. 752 789 .. 0.87 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 0.00065 EEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvr 35 tl H ++v+ +++++ g +++sGsdD ++ sp|Q58WW2|DCAF6_HUMAN 45 ATLNVHdGCVNTICWNDTGEYILSGSDDTKLV 76 67889*777*****************998876 PP == domain 2 score: 7.3 bits; conditional E-value: 0.55 ESS.SS...EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 8 tGH.ss...vtslafspdgaw.lasGsdDgtvriWd 38 t H + + + p+ ++ ++s+++Dgtvr +d sp|Q58WW2|DCAF6_HUMAN 138 TCHyGTtyeIMTV---PNDPYtFLSCGEDGTVRWFD 170 4665334567777...333333558999*****776 PP == domain 3 score: 5.4 bits; conditional E-value: 2.3 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +la G+ D +vri+d sp|Q58WW2|DCAF6_HUMAN 206 YLAVGCSDSSVRIYD 220 6888866*******8 PP == domain 4 score: 4.7 bits; conditional E-value: 3.7 SS.SS....EEEEEEETTSSEEEEE.ETTS CS WD40 9 GH.ss....vtslafspdgawlasG.sdDg 32 H ++ vtsl++s dg+ ++ + s sp|Q58WW2|DCAF6_HUMAN 247 SHlNNkscrVTSLCYSEDGQEILVSyS-SD 275 577444578***********9887644.44 PP == domain 5 score: 10.4 bits; conditional E-value: 0.06 EEESS.SS........EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ss........vtslafspdgawlasGsdDgtvriWd 38 +++GH +s ++ ++++sGsd g++ iWd sp|Q58WW2|DCAF6_HUMAN 712 VYKGHrNSrtmikeanFWGA------NFVMSGSDCGHIFIWD 747 68999988888444443455......889************9 PP == domain 6 score: 14.8 bits; conditional E-value: 0.0024 SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ss.vtslafspdgawlasGsdDgtvriWd 38 ++ v++l+ +p + las++ D ++iW+ sp|Q58WW2|DCAF6_HUMAN 761 NHvVNCLQPHPFDPILASSGIDYDIKIWS 789 4546************************5 PP >> tr|G5E996|G5E996_HUMAN WD repeat domain 31, isoform CRA_c OS=Homo sapiens GN=WDR31 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 0.0 9.3e-08 7.5e-06 3 38 .] 13 49 .. 11 49 .. 0.89 2 ! 15.2 0.0 0.0018 0.15 13 38 .] 66 91 .. 51 91 .. 0.84 3 ! 17.7 0.0 0.00029 0.023 4 38 .] 146 185 .. 143 185 .. 0.74 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 9.3e-08 EEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 + + l GH vt+la+spd++ l++Gs+D+t+ +Wd tr|G5E996|G5E996_HUMAN 13 PRQQLCGH-AmvVTGLAVSPDSSQLCTGSRDNTLLLWD 49 667788**.6668************************9 PP == domain 2 score: 15.2 bits; conditional E-value: 0.0018 EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 13 vtslafspdgawla.sGsdDgtvriWd 38 vt+l++ p ++++ + s+D+t+r+Wd tr|G5E996|G5E996_HUMAN 66 VTHLCWVPREPYILqT-SEDKTLRLWD 91 8*************77.66*******9 PP == domain 3 score: 17.7 bits; conditional E-value: 0.00029 EEEEESS.SSE.EEEEEETTSSE..........EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssv.tslafspdgaw..........lasGsdDgtvriWd 38 + +++GH + v +++ + +a++s D++v+iW+ tr|G5E996|G5E996_HUMAN 146 ICEYKGHfQTVaSCV-------FlpralalmplIATSSHDCKVKIWN 185 56899**77796666.......44555556887788888*******8 PP >> tr|J3KSS5|J3KSS5_HUMAN Coronin OS=Homo sapiens GN=CORO6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.2 4.7e-06 0.00038 8 37 .. 78 109 .. 72 110 .. 0.86 2 ! 17.0 0.1 0.00048 0.039 2 38 .] 122 160 .. 121 160 .. 0.84 3 ! 19.1 0.2 0.00011 0.0088 10 38 .] 174 203 .. 165 203 .. 0.87 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 4.7e-06 ESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawla.sGsdDgtvriW 37 tGH +v +++++p+++ ++ s+sdD t+++W tr|J3KSS5|J3KSS5_HUMAN 78 TGHtAPVLDIDWCPHNDNVIaSASDDTTIMVW 109 7**888************762679******** PP == domain 2 score: 17.0 bits; conditional E-value: 0.00048 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v l+++p + l++G+ D+ + iW+ tr|J3KSS5|J3KSS5_HUMAN 122 EPIITLEGHsKRVGILSWHPTARNvlLSAGG-DNVIIIWN 160 57899****888*9999*******4334778.*******8 PP == domain 3 score: 19.1 bits; conditional E-value: 0.00011 SSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriWd 38 H + ++s++++++g++la+ ++D+t+ri d tr|J3KSS5|J3KSS5_HUMAN 174 H-PdvIHSVCWNSNGSLLATTCKDKTLRIID 203 6.3347*************99*******966 PP >> sp|Q6QEF8|CORO6_HUMAN Coronin-6 OS=Homo sapiens GN=CORO6 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.2 4.7e-06 0.00038 8 37 .. 78 109 .. 72 110 .. 0.86 2 ! 17.0 0.1 0.00048 0.039 2 38 .] 122 160 .. 121 160 .. 0.84 3 ! 19.1 0.2 0.00011 0.0088 10 38 .] 174 203 .. 165 203 .. 0.87 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 4.7e-06 ESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawla.sGsdDgtvriW 37 tGH +v +++++p+++ ++ s+sdD t+++W sp|Q6QEF8|CORO6_HUMAN 78 TGHtAPVLDIDWCPHNDNVIaSASDDTTIMVW 109 7**888************762679******** PP == domain 2 score: 17.0 bits; conditional E-value: 0.00048 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v l+++p + l++G+ D+ + iW+ sp|Q6QEF8|CORO6_HUMAN 122 EPIITLEGHsKRVGILSWHPTARNvlLSAGG-DNVIIIWN 160 57899****888*9999*******4334778.*******8 PP == domain 3 score: 19.1 bits; conditional E-value: 0.00011 SSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriWd 38 H + ++s++++++g++la+ ++D+t+ri d sp|Q6QEF8|CORO6_HUMAN 174 H-PdvIHSVCWNSNGSLLATTCKDKTLRIID 203 6.3347*************99*******966 PP >> sp|Q58WW2-2|DCAF6_HUMAN Isoform 2 of DDB1- and CUL4-associated factor 6 OS=Homo sapiens GN=DCAF6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.1 0.00067 0.054 5 35 .. 45 76 .. 41 77 .. 0.86 2 ? 7.3 0.0 0.57 46 8 38 .] 138 170 .. 132 170 .. 0.60 3 ? 5.4 0.0 2.4 1.9e+02 24 38 .] 206 220 .. 193 220 .. 0.78 4 ? 4.7 0.0 3.8 3e+02 9 32 .. 247 275 .. 241 281 .. 0.71 5 ? 10.4 0.1 0.061 5 6 38 .] 732 767 .. 729 767 .. 0.77 6 ! 14.8 0.0 0.0024 0.2 11 38 .] 781 809 .. 772 809 .. 0.87 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 0.00067 EEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvr 35 tl H ++v+ +++++ g +++sGsdD ++ sp|Q58WW2-2|DCAF6_HUMAN 45 ATLNVHdGCVNTICWNDTGEYILSGSDDTKLV 76 67889*777*****************998876 PP == domain 2 score: 7.3 bits; conditional E-value: 0.57 ESS.SS...EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 8 tGH.ss...vtslafspdgaw.lasGsdDgtvriWd 38 t H + + + p+ ++ ++s+++Dgtvr +d sp|Q58WW2-2|DCAF6_HUMAN 138 TCHyGTtyeIMTV---PNDPYtFLSCGEDGTVRWFD 170 4665334567777...333333558999*****776 PP == domain 3 score: 5.4 bits; conditional E-value: 2.4 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +la G+ D +vri+d sp|Q58WW2-2|DCAF6_HUMAN 206 YLAVGCSDSSVRIYD 220 6888866*******8 PP == domain 4 score: 4.7 bits; conditional E-value: 3.8 SS.SS....EEEEEEETTSSEEEEE.ETTS CS WD40 9 GH.ss....vtslafspdgawlasG.sdDg 32 H ++ vtsl++s dg+ ++ + s sp|Q58WW2-2|DCAF6_HUMAN 247 SHlNNkscrVTSLCYSEDGQEILVSyS-SD 275 577444578***********9887644.44 PP == domain 5 score: 10.4 bits; conditional E-value: 0.061 EEESS.SS........EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ss........vtslafspdgawlasGsdDgtvriWd 38 +++GH +s ++ ++++sGsd g++ iWd sp|Q58WW2-2|DCAF6_HUMAN 732 VYKGHrNSrtmikeanFWGA------NFVMSGSDCGHIFIWD 767 68999988888444443455......889************9 PP == domain 6 score: 14.8 bits; conditional E-value: 0.0024 SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ss.vtslafspdgawlasGsdDgtvriWd 38 ++ v++l+ +p + las++ D ++iW+ sp|Q58WW2-2|DCAF6_HUMAN 781 NHvVNCLQPHPFDPILASSGIDYDIKIWS 809 4546************************5 PP >> tr|F8W6T6|F8W6T6_HUMAN Transducin-like enhancer protein 4 OS=Homo sapiens GN=TLE4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.038 3.1 10 38 .] 461 489 .. 453 489 .. 0.83 2 ? 7.2 0.0 0.6 49 12 38 .] 510 536 .. 492 536 .. 0.87 3 ! 12.9 0.2 0.0098 0.8 14 38 .] 556 580 .. 546 580 .. 0.85 4 ! 16.1 0.8 0.00092 0.075 3 38 .] 586 622 .. 584 622 .. 0.86 5 ? 7.0 0.0 0.73 59 7 34 .. 629 659 .. 624 661 .. 0.76 6 ? 9.6 0.1 0.11 8.8 10 37 .. 675 703 .. 669 704 .. 0.85 7 ? 6.5 0.1 1 83 11 33 .. 718 740 .. 710 745 .. 0.82 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.038 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H+ v+++ s + + +G+ +g v++Wd tr|F8W6T6|F8W6T6_HUMAN 461 HGEvVCAVTISNPTRHVYTGG-KGCVKVWD 489 7555799999999999*****.*******9 PP == domain 2 score: 7.2 bits; conditional E-value: 0.6 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|F8W6T6|F8W6T6_HUMAN 510 YIRSCRLLPDGRTLIVGGEASTLSIWD 536 3889999*******************9 PP == domain 3 score: 12.9 bits; conditional E-value: 0.0098 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd++ +s++ Dg++ +Wd tr|F8W6T6|F8W6T6_HUMAN 556 YALAISPDSKVCFSCCSDGNIAVWD 580 6899*******887755*******9 PP == domain 4 score: 16.1 bits; conditional E-value: 0.00092 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s dg+ l +G+ D+tvr Wd tr|F8W6T6|F8W6T6_HUMAN 586 LVRQFQGHtDGASCIDISNDGTKLWTGGLDNTVRSWD 622 6899****777999999999999647999*******9 PP == domain 5 score: 7.0 bits; conditional E-value: 0.73 EESS..SS.EEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH..ss.vtslafspdgawlasGsdDgtv 34 l H +s + sl ++p g wla G+++ +v tr|F8W6T6|F8W6T6_HUMAN 629 LQQHdfTSqIFSLGYCPTGEWLAVGMENSNV 659 556753226****************988777 PP == domain 6 score: 9.6 bits; conditional E-value: 0.11 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W tr|F8W6T6|F8W6T6_HUMAN 675 HeSCVLSLKFAHCGKWFVSTGKDNLLNAW 703 7778**************99999987766 PP == domain 7 score: 6.5 bits; conditional E-value: 1 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|F8W6T6|F8W6T6_HUMAN 718 SSVLSCDISVDDKYIVTGSGDKK 740 45999*************87986 PP >> tr|H3BRJ0|H3BRJ0_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.2 9e-07 7.3e-05 7 37 .. 77 109 .. 72 110 .. 0.86 2 ! 17.6 0.1 0.00031 0.025 2 38 .] 122 160 .. 121 160 .. 0.79 3 ! 18.9 0.0 0.00013 0.01 9 36 .. 174 202 .. 167 204 .. 0.89 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 9e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH +v ++a++p+++ + asGs+D+tv++W tr|H3BRJ0|H3BRJ0_HUMAN 77 VCGHtAPVLDIAWCPHNDNViASGSEDCTVMVW 109 459*888************73699********* PP == domain 2 score: 17.6 bits; conditional E-value: 0.00031 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v +a++ + l++G+ D+ +++Wd tr|H3BRJ0|H3BRJ0_HUMAN 122 EPVVTLEGHtKRVGIVAWHTTAQNvlLSAGC-DNVIMVWD 160 68899****9889888777777774344677.*******9 PP == domain 3 score: 18.9 bits; conditional E-value: 0.00013 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 H + ++s+++s+dg +++++++D+ vri tr|H3BRJ0|H3BRJ0_HUMAN 174 VHpDTIYSVDWSRDGGLICTSCRDKRVRI 202 68777**************9999*****9 PP >> sp|Q04727|TLE4_HUMAN Transducin-like enhancer protein 4 OS=Homo sapiens GN=TLE4 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.039 3.2 10 38 .] 486 514 .. 478 514 .. 0.83 2 ? 7.2 0.0 0.63 51 12 38 .] 535 561 .. 517 561 .. 0.87 3 ? 12.8 0.2 0.01 0.83 14 38 .] 581 605 .. 571 605 .. 0.85 4 ! 16.1 0.8 0.00096 0.078 3 38 .] 611 647 .. 609 647 .. 0.86 5 ? 6.9 0.0 0.76 61 7 34 .. 654 684 .. 649 686 .. 0.76 6 ? 9.5 0.1 0.11 9.2 10 37 .. 700 728 .. 694 729 .. 0.85 7 ? 6.4 0.1 1.1 87 11 33 .. 743 765 .. 735 770 .. 0.82 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.039 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H+ v+++ s + + +G+ +g v++Wd sp|Q04727|TLE4_HUMAN 486 HGEvVCAVTISNPTRHVYTGG-KGCVKVWD 514 7555799999999999*****.*******9 PP == domain 2 score: 7.2 bits; conditional E-value: 0.63 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04727|TLE4_HUMAN 535 YIRSCRLLPDGRTLIVGGEASTLSIWD 561 3889999*******************9 PP == domain 3 score: 12.8 bits; conditional E-value: 0.01 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd++ +s++ Dg++ +Wd sp|Q04727|TLE4_HUMAN 581 YALAISPDSKVCFSCCSDGNIAVWD 605 6899*******887755*******9 PP == domain 4 score: 16.1 bits; conditional E-value: 0.00096 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s dg+ l +G+ D+tvr Wd sp|Q04727|TLE4_HUMAN 611 LVRQFQGHtDGASCIDISNDGTKLWTGGLDNTVRSWD 647 6899****777999999999999647999*******9 PP == domain 5 score: 6.9 bits; conditional E-value: 0.76 EESS..SS.EEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH..ss.vtslafspdgawlasGsdDgtv 34 l H +s + sl ++p g wla G+++ +v sp|Q04727|TLE4_HUMAN 654 LQQHdfTSqIFSLGYCPTGEWLAVGMENSNV 684 556753226****************988777 PP == domain 6 score: 9.5 bits; conditional E-value: 0.11 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W sp|Q04727|TLE4_HUMAN 700 HeSCVLSLKFAHCGKWFVSTGKDNLLNAW 728 7778**************99999987766 PP == domain 7 score: 6.4 bits; conditional E-value: 1.1 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ sp|Q04727|TLE4_HUMAN 743 SSVLSCDISVDDKYIVTGSGDKK 765 45999*************87986 PP >> tr|G3V201|G3V201_HUMAN HCG1985539, isoform CRA_e OS=Homo sapiens GN=WDR90 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.0 2.7e-05 0.0022 2 37 .. 15 61 .. 14 61 .. 0.84 2 ? 7.5 0.0 0.49 39 18 37 .. 90 109 .. 73 110 .. 0.71 3 ! 12.9 0.0 0.0099 0.8 10 34 .. 121 148 .. 114 150 .. 0.80 4 ? 9.0 0.2 0.16 13 3 37 .. 158 203 .. 156 203 .. 0.78 5 ? 4.7 0.0 3.9 3.2e+02 7 37 .. 312 342 .. 308 343 .. 0.80 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 2.7e-05 EEEEEEE....SS.SS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtlt....GH.ss......vtslafspdgawlasGsdDgtvriW 37 +clr +t H ++ v+ + fsp + a++s+Dg+vr+W tr|G3V201|G3V201_HUMAN 15 KCLRPFTlprgQHpQPsygfpqVNEVVFSPGESHCATCSEDGSVRVW 61 6888876666556655778899************************* PP == domain 2 score: 7.5 bits; conditional E-value: 0.49 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 p+++ la+G Dg++ri+ tr|G3V201|G3V201_HUMAN 90 GRPEQQRLAAGYGDGSLRIF 109 5677777****55******7 PP == domain 3 score: 12.9 bits; conditional E-value: 0.0099 S.SSE..EEEEEETTSSEEEEEETTSEE CS WD40 10 H.ssv..tslafspdgawlasGsdDgtv 34 H +v t +afs dg+ ++sG++Dg v tr|G3V201|G3V201_HUMAN 121 HpHPValTTVAFSTDGQTVLSGDKDGLV 148 5335444******************976 PP == domain 4 score: 9.0 bits; conditional E-value: 0.16 EEEEEESS..SSEEEEE..........EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH..ssvtsla..........fspdgawlasGsdDgtvriW 37 + r+l+ H +++ ++ + wla+++ D+ v +W tr|G3V201|G3V201_HUMAN 158 TFRVLSDHqgAPISTICvtckecedlgVEGTDLWLAASG-DQRVSVW 203 567888886444766666688888888888999***999.******* PP == domain 5 score: 4.7 bits; conditional E-value: 3.9 EESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 + GH + v +l+ f p+ ++l+++ + + +W tr|G3V201|G3V201_HUMAN 312 FAGHdNAV-HLCrFTPSARLLFTAA-RNEILVW 342 77**8889.6666********9988.7777776 PP >> sp|Q58WW2-3|DCAF6_HUMAN Isoform 3 of DDB1- and CUL4-associated factor 6 OS=Homo sapiens GN=DCAF6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.1 0.00073 0.059 5 35 .. 45 76 .. 41 77 .. 0.86 2 ? 7.2 0.0 0.62 50 8 38 .] 138 170 .. 132 170 .. 0.60 3 ? 5.2 0.0 2.6 2.1e+02 24 38 .] 206 220 .. 193 220 .. 0.78 4 ? 4.6 0.0 4.1 3.3e+02 9 32 .. 247 275 .. 241 281 .. 0.71 5 ? 10.2 0.1 0.067 5.4 6 38 .] 803 838 .. 800 838 .. 0.77 6 ! 14.7 0.0 0.0026 0.21 11 38 .] 852 880 .. 843 880 .. 0.87 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 0.00073 EEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvr 35 tl H ++v+ +++++ g +++sGsdD ++ sp|Q58WW2-3|DCAF6_HUMAN 45 ATLNVHdGCVNTICWNDTGEYILSGSDDTKLV 76 67889*777*****************998876 PP == domain 2 score: 7.2 bits; conditional E-value: 0.62 ESS.SS...EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 8 tGH.ss...vtslafspdgaw.lasGsdDgtvriWd 38 t H + + + p+ ++ ++s+++Dgtvr +d sp|Q58WW2-3|DCAF6_HUMAN 138 TCHyGTtyeIMTV---PNDPYtFLSCGEDGTVRWFD 170 4665334567777...333333558999*****776 PP == domain 3 score: 5.2 bits; conditional E-value: 2.6 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +la G+ D +vri+d sp|Q58WW2-3|DCAF6_HUMAN 206 YLAVGCSDSSVRIYD 220 6888866*******8 PP == domain 4 score: 4.6 bits; conditional E-value: 4.1 SS.SS....EEEEEEETTSSEEEEE.ETTS CS WD40 9 GH.ss....vtslafspdgawlasG.sdDg 32 H ++ vtsl++s dg+ ++ + s sp|Q58WW2-3|DCAF6_HUMAN 247 SHlNNkscrVTSLCYSEDGQEILVSyS-SD 275 577444578***********9887644.44 PP == domain 5 score: 10.2 bits; conditional E-value: 0.067 EEESS.SS........EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ss........vtslafspdgawlasGsdDgtvriWd 38 +++GH +s ++ ++++sGsd g++ iWd sp|Q58WW2-3|DCAF6_HUMAN 803 VYKGHrNSrtmikeanFWGA------NFVMSGSDCGHIFIWD 838 68999988888444443455......889************9 PP == domain 6 score: 14.7 bits; conditional E-value: 0.0026 SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ss.vtslafspdgawlasGsdDgtvriWd 38 ++ v++l+ +p + las++ D ++iW+ sp|Q58WW2-3|DCAF6_HUMAN 852 NHvVNCLQPHPFDPILASSGIDYDIKIWS 880 4546************************5 PP >> sp|Q149M9|NWD1_HUMAN NACHT and WD repeat domain-containing protein 1 OS=Homo sapiens GN=NWD1 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.0 0.098 7.9 6 38 .] 863 896 .. 858 896 .. 0.87 2 ! 17.5 0.1 0.00035 0.028 4 38 .] 903 938 .. 900 938 .. 0.87 3 ? 4.6 0.1 4 3.2e+02 13 38 .] 1003 1028 .. 988 1028 .. 0.76 4 ! 13.4 0.0 0.0065 0.53 7 38 .] 1384 1416 .. 1379 1416 .. 0.93 5 ? 12.5 0.2 0.013 1.1 12 38 .] 1434 1461 .. 1422 1461 .. 0.83 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.098 EEE.SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tlt.GHssvtslafspdgawlasGsdDgtvriWd 38 tl+ H+++t++a+ + ++l+ G+ Dg +Wd sp|Q149M9|NWD1_HUMAN 863 TLSgCHKGITAMAWGVEEKLLVIGTQDGIMAVWD 896 56635699****99999999*************9 PP == domain 2 score: 17.5 bits; conditional E-value: 0.00035 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ ltGH + v++++ g++ a s+s+D t+++W+ sp|Q149M9|NWD1_HUMAN 903 IHMLTGHtGEVRCVKIFAKGTL-AnSASKDYTLHLWN 938 7889***777****99999999.87789********8 PP == domain 3 score: 4.6 bits; conditional E-value: 4 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++a+ ++a l++ s+Dg v +W+ sp|Q149M9|NWD1_HUMAN 1003 WMCMAVLASQATLLTVSRDGVVSLWS 1028 4588888888899999*********5 PP == domain 4 score: 13.4 bits; conditional E-value: 0.0065 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++H s v ++ +s+ ++++sGs+D + +Wd sp|Q149M9|NWD1_HUMAN 1384 LETHrSRVACVEVSHKEQLVVSGSEDALLCLWD 1416 679*899*************************9 PP == domain 5 score: 12.5 bits; conditional E-value: 0.013 S.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriWd 38 v + +fs+d +++ G +D+++ +W+ sp|Q149M9|NWD1_HUMAN 1434 RgVQCACFSKDDKYVYVGLKDRSILVWS 1461 2499**************9********5 PP >> tr|B4DGB8|B4DGB8_HUMAN WD repeat and SOCS box-containing protein 1 OS=Homo sapiens GN=WSB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 0.032 2.6 17 38 .] 83 125 .. 64 125 .. 0.71 2 ! 27.4 0.0 2.6e-07 2.1e-05 2 38 .] 130 168 .. 129 168 .. 0.84 3 ! 21.2 0.0 2.3e-05 0.0019 2 28 .. 174 201 .. 173 208 .. 0.84 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.032 E.....................EETTSSEEEEEETTSEEEEEE CS WD40 17 a.....................fspdgawlasGsdDgtvriWd 38 a f +d+ +la+G +g ++iWd tr|B4DGB8|B4DGB8_HUMAN 83 AfgssvpekqsrcvniewhrfrFGQDQLLLATGLNNGRIKIWD 125 55555555555555566666668899999****77*******9 PP == domain 2 score: 27.4 bits; conditional E-value: 2.6e-07 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 ++l l H+ v++l f pdg+++ +s+s+D+t+r+Wd tr|B4DGB8|B4DGB8_HUMAN 130 KLLLNLVDHTEvVRDLTFAPDGSLIlVSASRDKTLRVWD 168 6677788896657***********62589*********9 PP == domain 3 score: 21.2 bits; conditional E-value: 2.3e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG 28 + +++l+GH ++v+s+afspd+++l+s tr|B4DGB8|B4DGB8_HUMAN 174 NMMKVLRGHqNWVYSCAFSPDSSMLCSV 201 66899****999************9764 PP >> tr|H0Y9I6|H0Y9I6_HUMAN Intraflagellar transport protein 122 homolog (Fragment) OS=Homo sapiens GN=IFT122 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.81 65 13 34 .. 2 32 .. 1 34 [. 0.77 2 ! 31.1 0.0 1.7e-08 1.4e-06 2 37 .. 31 67 .. 30 68 .. 0.91 3 ? 8.0 0.1 0.34 27 7 31 .. 77 100 .. 70 107 .. 0.75 4 ! 13.5 0.1 0.0061 0.49 7 37 .. 196 227 .. 190 228 .. 0.79 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.81 EEEEEEETTSSE..EEEEET.......TSEE CS WD40 13 vtslafspdgaw..lasGsd.......Dgtv 34 ++++af pdg+ la+Gs+ Dgt+ tr|H0Y9I6|H0Y9I6_HUMAN 2 INDIAFKPDGTQliLAAGSRllvydtsDGTL 32 89**********4446898666666667776 PP == domain 2 score: 31.1 bits; conditional E-value: 1.7e-08 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 ++l+ l+GH++ v+++a+ +dg+ +asGs D++v iW tr|H0Y9I6|H0Y9I6_HUMAN 31 TLLQPLKGHKDtVYCVAYAKDGKRFASGSADKSVIIW 67 67899****555************************* PP == domain 3 score: 8.0 bits; conditional E-value: 0.34 EESSSS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGHss.vtslafspdgawlasGsdD 31 + +H++ + +++++p + las+s tr|H0Y9I6|H0Y9I6_HUMAN 77 Y-THNDaIQCVSYNPITHQLASCS-S 100 3.69556********9999**997.3 PP == domain 4 score: 13.5 bits; conditional E-value: 0.0061 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ tr|H0Y9I6|H0Y9I6_HUMAN 196 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 227 444545698888*****************876 PP >> tr|Q4VXH1|Q4VXH1_HUMAN F-box/WD repeat-containing protein 2 (Fragment) OS=Homo sapiens GN=FBXW2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.1 0.0042 0.34 5 38 .] 13 45 .. 10 45 .. 0.78 2 ? 10.4 0.1 0.061 4.9 1 37 [. 49 82 .. 49 83 .. 0.89 3 ! 26.7 0.1 4.3e-07 3.5e-05 4 37 .. 90 124 .. 87 124 .. 0.92 4 ! 15.2 0.1 0.0018 0.15 1 37 [. 129 175 .. 129 175 .. 0.78 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.0042 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH v++l + +dg l++GsdD + ++Wd tr|Q4VXH1|Q4VXH1_HUMAN 13 SSLIGHsARVYAL-YYKDGL-LCTGSDDLSAKLWD 45 6799**555**99.444444.589**********9 PP == domain 2 score: 10.4 bits; conditional E-value: 0.061 TEEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHssvtslafspdgawlasGsdDgtvriW 37 gqc++ + +H t+ a+ d + l++Gs D+tv W tr|Q4VXH1|Q4VXH1_HUMAN 49 GQCVYGIQTH---TCAAVKFDEQKLVTGSFDNTVACW 82 6888888899...89999999999**********999 PP == domain 3 score: 26.7 bits; conditional E-value: 4.3e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++++GH + v s++++++ + l+sGs D tv++W tr|Q4VXH1|Q4VXH1_HUMAN 90 TQHFRGHtGAVFSVDYNDELDILVSGSADFTVKVW 124 689****777************************* PP == domain 4 score: 15.2 bits; conditional E-value: 0.0018 TEEEEEEESS.SSEEEEE..........EETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtsla..........fspdgawlasGsdDgtvriW 37 g+cl tltGH +vt + sp l+s++ + ++iW tr|Q4VXH1|Q4VXH1_HUMAN 129 GTCLNTLTGHtEWVTKVVlqkckvksllHSPGDYILLSAD-KYEIKIW 175 68********777887777777777884666666678877.******* PP >> sp|Q04727-3|TLE4_HUMAN Isoform 3 of Transducin-like enhancer protein 4 OS=Homo sapiens GN=TLE4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.1 0.041 3.4 10 38 .] 518 546 .. 510 546 .. 0.83 2 ? 7.1 0.0 0.66 53 12 38 .] 567 593 .. 549 593 .. 0.87 3 ? 12.8 0.2 0.011 0.87 14 38 .] 613 637 .. 603 637 .. 0.85 4 ! 16.0 0.8 0.001 0.082 3 38 .] 643 679 .. 641 679 .. 0.86 5 ? 6.8 0.0 0.8 64 7 34 .. 686 716 .. 681 718 .. 0.76 6 ? 9.5 0.1 0.12 9.6 10 37 .. 732 760 .. 726 761 .. 0.85 7 ? 6.4 0.1 1.1 91 11 33 .. 775 797 .. 767 802 .. 0.82 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.041 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H+ v+++ s + + +G+ +g v++Wd sp|Q04727-3|TLE4_HUMAN 518 HGEvVCAVTISNPTRHVYTGG-KGCVKVWD 546 7555799999999999*****.*******9 PP == domain 2 score: 7.1 bits; conditional E-value: 0.66 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04727-3|TLE4_HUMAN 567 YIRSCRLLPDGRTLIVGGEASTLSIWD 593 3889999*******************9 PP == domain 3 score: 12.8 bits; conditional E-value: 0.011 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd++ +s++ Dg++ +Wd sp|Q04727-3|TLE4_HUMAN 613 YALAISPDSKVCFSCCSDGNIAVWD 637 6899*******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s dg+ l +G+ D+tvr Wd sp|Q04727-3|TLE4_HUMAN 643 LVRQFQGHtDGASCIDISNDGTKLWTGGLDNTVRSWD 679 6899****777999999999999647999*******9 PP == domain 5 score: 6.8 bits; conditional E-value: 0.8 EESS..SS.EEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH..ss.vtslafspdgawlasGsdDgtv 34 l H +s + sl ++p g wla G+++ +v sp|Q04727-3|TLE4_HUMAN 686 LQQHdfTSqIFSLGYCPTGEWLAVGMENSNV 716 556753226****************988777 PP == domain 6 score: 9.5 bits; conditional E-value: 0.12 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W sp|Q04727-3|TLE4_HUMAN 732 HeSCVLSLKFAHCGKWFVSTGKDNLLNAW 760 7778**************99999987766 PP == domain 7 score: 6.4 bits; conditional E-value: 1.1 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ sp|Q04727-3|TLE4_HUMAN 775 SSVLSCDISVDDKYIVTGSGDKK 797 45999*************87986 PP >> tr|F8W9R0|F8W9R0_HUMAN Transducin-like enhancer protein 4 OS=Homo sapiens GN=TLE4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.1 0.041 3.4 10 38 .] 518 546 .. 510 546 .. 0.83 2 ? 7.1 0.0 0.66 53 12 38 .] 567 593 .. 549 593 .. 0.87 3 ? 12.8 0.2 0.011 0.87 14 38 .] 613 637 .. 603 637 .. 0.85 4 ! 16.0 0.8 0.001 0.082 3 38 .] 643 679 .. 641 679 .. 0.86 5 ? 6.8 0.0 0.8 64 7 34 .. 686 716 .. 681 718 .. 0.76 6 ? 9.5 0.1 0.12 9.6 10 37 .. 732 760 .. 726 761 .. 0.85 7 ? 6.4 0.1 1.1 91 11 33 .. 775 797 .. 767 802 .. 0.82 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.041 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H+ v+++ s + + +G+ +g v++Wd tr|F8W9R0|F8W9R0_HUMAN 518 HGEvVCAVTISNPTRHVYTGG-KGCVKVWD 546 7555799999999999*****.*******9 PP == domain 2 score: 7.1 bits; conditional E-value: 0.66 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|F8W9R0|F8W9R0_HUMAN 567 YIRSCRLLPDGRTLIVGGEASTLSIWD 593 3889999*******************9 PP == domain 3 score: 12.8 bits; conditional E-value: 0.011 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd++ +s++ Dg++ +Wd tr|F8W9R0|F8W9R0_HUMAN 613 YALAISPDSKVCFSCCSDGNIAVWD 637 6899*******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s dg+ l +G+ D+tvr Wd tr|F8W9R0|F8W9R0_HUMAN 643 LVRQFQGHtDGASCIDISNDGTKLWTGGLDNTVRSWD 679 6899****777999999999999647999*******9 PP == domain 5 score: 6.8 bits; conditional E-value: 0.8 EESS..SS.EEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH..ss.vtslafspdgawlasGsdDgtv 34 l H +s + sl ++p g wla G+++ +v tr|F8W9R0|F8W9R0_HUMAN 686 LQQHdfTSqIFSLGYCPTGEWLAVGMENSNV 716 556753226****************988777 PP == domain 6 score: 9.5 bits; conditional E-value: 0.12 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f + g+w++s ++D+ + W tr|F8W9R0|F8W9R0_HUMAN 732 HeSCVLSLKFAHCGKWFVSTGKDNLLNAW 760 7778**************99999987766 PP == domain 7 score: 6.4 bits; conditional E-value: 1.1 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|F8W9R0|F8W9R0_HUMAN 775 SSVLSCDISVDDKYIVTGSGDKK 797 45999*************87986 PP >> sp|Q96MR6-2|WDR65_HUMAN Isoform 2 of WD repeat-containing protein 65 OS=Homo sapiens GN=WDR65 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 1.1 93 12 31 .. 340 359 .. 330 363 .. 0.78 2 ! 16.8 0.0 0.00058 0.047 10 38 .] 388 417 .. 382 417 .. 0.90 3 ! 18.9 0.2 0.00013 0.01 2 38 .] 503 540 .. 502 540 .. 0.90 4 ? 7.4 0.1 0.53 43 14 35 .. 558 579 .. 551 579 .. 0.86 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 1.1 SEEEEEEETTSSEEEEE.ETT CS WD40 12 svtslafspdgawlasG.sdD 31 +v +l+fsp+ l+++ s + sp|Q96MR6-2|WDR65_HUMAN 340 DVLCLCFSPSEETLVAStS-K 359 599**********987634.4 PP == domain 2 score: 16.8 bits; conditional E-value: 0.00058 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H ++t+la++ ++++a++s D+++r+W+ sp|Q96MR6-2|WDR65_HUMAN 388 HsAPITGLATCIRKPLIATCSLDRSIRLWN 417 856699999999*****************8 PP == domain 3 score: 18.9 bits; conditional E-value: 0.00013 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +l+GH + ++s+ ++ d + l+sG+ Dg v+ W+ sp|Q96MR6-2|WDR65_HUMAN 503 ENISSLKGHtGKIRSIVWNADDSKLISGGTDGAVYEWN 540 57899****666****************99****9997 PP == domain 4 score: 7.4 bits; conditional E-value: 0.53 EEEEEETTSSEE.EEEETTSEEE CS WD40 14 tslafspdgawl.asGsdDgtvr 35 +++ +spd + + a Gs D+t++ sp|Q96MR6-2|WDR65_HUMAN 558 NCVTVSPDAKIIfAVGS-DHTLK 579 7999*******835789.***97 PP >> sp|Q5XX13-3|FBW10_HUMAN Isoform 3 of F-box/WD repeat-containing protein 10 OS=Homo sapiens GN=FBXW10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 0.0016 0.13 6 38 .] 448 481 .. 445 481 .. 0.95 2 ! 25.8 0.6 8.4e-07 6.8e-05 1 38 [] 485 521 .. 485 521 .. 0.88 3 ? 7.3 0.1 0.55 45 1 37 [. 525 559 .. 525 560 .. 0.89 4 ! 14.4 0.2 0.0032 0.26 2 37 .. 565 599 .. 564 600 .. 0.83 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0016 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH +sv++l + + ++l+sGs+D ++r Wd sp|Q5XX13-3|FBW10_HUMAN 448 EFRGHaGSVRALFLCEEENFLLSGSYDLSIRYWD 481 599**999*************************9 PP == domain 2 score: 25.8 bits; conditional E-value: 8.4e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g c+r++ GH + +t++ ++ l+sG++D+ v++Wd sp|Q5XX13-3|FBW10_HUMAN 485 GVCTRIFGGHqGTITCM------DLcknrLVSGGRDCQVKVWD 521 579*******777****......66666699***********9 PP == domain 3 score: 7.3 bits; conditional E-value: 0.55 TEEEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssv..tslafspdgawlasGsdDgtvriW 37 g+cl+t++ H +++ t + + ++++s+++ g v++W sp|Q5XX13-3|FBW10_HUMAN 525 GKCLKTFR-HkDPIlaTRI----NDTYIVSSCERGLVKVW 559 79*****9.9666778999....9*****9999******* PP == domain 4 score: 14.4 bits; conditional E-value: 0.0032 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 q+++tl+GH + v +l f +w l+sGs Dg v+ W sp|Q5XX13-3|FBW10_HUMAN 565 QLVKTLSGHeGAVKCLFF---DQWhLLSGSTDGLVMAW 599 789******888****54...477557********999 PP >> sp|Q9Y6I7-3|WSB1_HUMAN Isoform 3 of WD repeat and SOCS box-containing protein 1 OS=Homo sapiens GN=WSB1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.1 0.04 3.3 17 38 .] 124 156 .. 95 156 .. 0.71 2 ! 27.1 0.0 3.2e-07 2.6e-05 2 38 .] 161 199 .. 160 199 .. 0.83 3 ! 20.9 0.0 2.8e-05 0.0023 2 28 .. 205 232 .. 204 239 .. 0.84 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.04 E...........EETTSSEEEEEETTSEEEEEE CS WD40 17 a...........fspdgawlasGsdDgtvriWd 38 + f +d+ +la+G +g ++iWd sp|Q9Y6I7-3|WSB1_HUMAN 124 SrcvniewhrfrFGQDQLLLATGLNNGRIKIWD 156 0555566666668899999****77*******9 PP == domain 2 score: 27.1 bits; conditional E-value: 3.2e-07 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 ++l l H+ v++l f pdg+++ +s+s+D+t+r+Wd sp|Q9Y6I7-3|WSB1_HUMAN 161 KLLLNLVDHTEvVRDLTFAPDGSLIlVSASRDKTLRVWD 199 6677788896657***********62589*********9 PP == domain 3 score: 20.9 bits; conditional E-value: 2.8e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG 28 + +++l+GH ++v+s+afspd+++l+s sp|Q9Y6I7-3|WSB1_HUMAN 205 NMMKVLRGHqNWVYSCAFSPDSSMLCSV 232 66899****999************9764 PP >> tr|H0YL98|H0YL98_HUMAN DDB1- and CUL4-associated factor 11 (Fragment) OS=Homo sapiens GN=DCAF11 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.93 76 13 38 .] 8 33 .. 3 33 .. 0.89 2 ! 18.3 0.0 0.0002 0.016 4 38 .] 38 76 .. 35 76 .. 0.75 3 ! 21.7 0.0 1.6e-05 0.0013 2 38 .] 86 123 .. 85 123 .. 0.92 4 ? 6.1 0.1 1.3 1.1e+02 4 38 .] 168 209 .. 166 209 .. 0.69 5 ? 8.4 0.1 0.26 21 3 29 .. 215 242 .. 213 244 .. 0.85 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.93 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v s+a+s+dg+ ++ G Dg ++++d tr|H0YL98|H0YL98_HUMAN 8 VFSIAVSSDGREVLGGANDGCLYVFD 33 889***********7778*****998 PP == domain 2 score: 18.3 bits; conditional E-value: 0.0002 EEEEE..SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 4 lrtlt..GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 rtl H ++v+++af + ++ l+sG+dD +++Wd tr|H0YL98|H0YL98_HUMAN 38 RRTLQieSHeDDVNAVAFADISSQiLFSGGDDAICKVWD 76 55653339*888****96666666356***********9 PP == domain 3 score: 21.7 bits; conditional E-value: 1.6e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ l GH +++t ++ d ++l+s s+D+t+++Wd tr|H0YL98|H0YL98_HUMAN 86 KPVGALAGHqDGITFIDSKGDARYLISNSKDQTIKLWD 123 5788899**777**************88*********9 PP == domain 4 score: 6.1 bits; conditional E-value: 1.3 EEEEESSSSE.EEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHssv.tsla.......fspdgawlasGsdDgtvriWd 38 l t++GH +v + l s ++++ sG+ g+v ++d tr|H0YL98|H0YL98_HUMAN 168 LMTYRGH-GVlHTLIrcrfspiHSTGQQFIYSGCSTGKVVVYD 209 789****.75444445555576666667788997699998887 PP == domain 5 score: 8.4 bits; conditional E-value: 0.26 EEEEEESS.SSEEEEEEETTSSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGs 29 +++lt H +v++++++p ++s+s tr|H0YL98|H0YL98_HUMAN 215 IVKKLTNHkACVRDVSWHPFEEKIVSSS 242 578899**666*********99999887 PP >> sp|Q5JSH3-4|WDR44_HUMAN Isoform 4 of WD repeat-containing protein 44 OS=Homo sapiens GN=WDR44 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.1 0.0001 0.0081 9 37 .. 484 513 .. 475 513 .. 0.87 2 ! 22.1 0.1 1.2e-05 0.001 3 37 .. 574 608 .. 572 609 .. 0.85 3 ? 3.8 0.1 7.5 6.1e+02 13 38 .] 656 681 .. 613 681 .. 0.43 4 ! 15.2 0.1 0.0018 0.15 13 38 .] 701 725 .. 686 725 .. 0.74 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 0.0001 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 H + v+ ++fs+ g++las++ D+ vriW sp|Q5JSH3-4|WDR44_HUMAN 484 EHmGAVWTMKFSHCGRLLASAGQDNVVRIW 513 47888************************* PP == domain 2 score: 22.1 bits; conditional E-value: 1.2e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +++GH + +l++s++ +l+ +s+D+tvr+W sp|Q5JSH3-4|WDR44_HUMAN 574 PFCKYKGHtADLLDLSWSKNYFLLS-SSMDKTVRLW 608 56689***88899*******99985.666******* PP == domain 3 score: 3.8 bits; conditional E-value: 7.5 EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw.lasGsdDgtvriWd 38 +t++ p + l+++ D +r++d sp|Q5JSH3-4|WDR44_HUMAN 656 ITGIEPLPGENKiLVTSN-DSRIRLYD 681 333332222233244444.77777776 PP == domain 4 score: 15.2 bits; conditional E-value: 0.0018 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +fs+d ++l+sGs+D+ v+iW+ sp|Q5JSH3-4|WDR44_HUMAN 701 I-KASFSHDFTYLVSGSEDKYVYIWS 725 3.3459*******************5 PP >> tr|F8VSE4|F8VSE4_HUMAN WD repeat domain-containing protein 83 OS=Homo sapiens GN=WDR83 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 0.0 9.2e-07 7.4e-05 4 38 .] 18 53 .. 15 53 .. 0.80 2 ! 24.4 0.2 2.2e-06 0.00018 2 38 .] 58 95 .. 57 95 .. 0.91 3 ? 10.1 0.0 0.074 6 1 27 [. 99 126 .. 99 137 .. 0.84 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 9.2e-07 EEEEE.SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GHssvtslafspdgawlasGsdDgtvriWd 38 l+tl+ G++ v++++f+ dg++ ++++ D+t+++W+ tr|F8VSE4|F8VSE4_HUMAN 18 LKTLDcGQGAVRAVRFNVDGNYCLTCGSDKTLKLWN 53 6677656667************776655*******8 PP == domain 2 score: 24.4 bits; conditional E-value: 2.2e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++lrt++GH+ v + a s d++ l+sG+ D+ v +Wd tr|F8VSE4|F8VSE4_HUMAN 58 TLLRTYSGHGYeVLDAAGSFDNSSLCSGGGDKAVVLWD 95 789******446****************88*******9 PP == domain 3 score: 10.1 bits; conditional E-value: 0.074 TEEEEEEESS.SSEEEEEEETTSSEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlas 27 gq +r+++GH + v+ ++f+ + + ++s tr|F8VSE4|F8VSE4_HUMAN 99 GQVVRKFRGHaGKVNTVQFNEEATVILS 126 6889******777****99999888776 PP >> sp|Q8TBY9-2|WDR66_HUMAN Isoform 2 of WD repeat-containing protein 66 OS=Homo sapiens GN=WDR66 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.3 8.4e-07 6.8e-05 2 38 .] 290 329 .. 289 329 .. 0.92 2 ? 8.7 0.0 0.2 16 13 38 .] 609 634 .. 597 634 .. 0.91 3 ? 7.6 0.0 0.47 38 12 31 .. 695 714 .. 688 720 .. 0.80 4 ? 11.5 0.2 0.027 2.2 9 38 .] 889 920 .. 881 920 .. 0.84 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 8.4e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEET..TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsd..DgtvriWd 38 +++++l GH + +++l++s d +w+a++++ D+ v iWd sp|Q8TBY9-2|WDR66_HUMAN 290 NNQYHLQGHaNIISCLCVSEDRRWIATADKgpDCLVIIWD 329 799******7779**************98788*******9 PP == domain 2 score: 8.7 bits; conditional E-value: 0.2 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 +++++ +p+++++a Gs g +++W+ sp|Q8TBY9-2|WDR66_HUMAN 609 ICAISCHPYQPLIAIGSICGMIKVWN 634 999**********************8 PP == domain 3 score: 7.6 bits; conditional E-value: 0.47 SEEEEEEETTSSEEEEEETT CS WD40 12 svtslafspdgawlasGsdD 31 svt+++fs+d++++a++++ sp|Q8TBY9-2|WDR66_HUMAN 695 SVTHISFSHDSQYMATADRS 714 6*************987554 PP == domain 4 score: 11.5 bits; conditional E-value: 0.027 SS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawla.sGsdDgtvriWd 38 H ++v ++a+s dg + + +G+ D++v W+ sp|Q8TBY9-2|WDR66_HUMAN 889 CHpNGVAGMAVSYDGCYAFtAGGHDRSVVQWK 920 79999************6537788*******5 PP >> tr|F5H7D6|F5H7D6_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 0.012 0.98 6 38 .] 409 440 .. 404 440 .. 0.83 2 ? 6.2 0.0 1.3 1.1e+02 12 38 .] 461 487 .. 450 487 .. 0.91 3 ? 11.9 0.1 0.021 1.7 14 38 .] 507 531 .. 497 531 .. 0.85 4 ! 16.2 1.3 0.0009 0.073 3 38 .] 537 573 .. 535 573 .. 0.88 5 ? 6.0 0.0 1.5 1.2e+02 7 31 .. 580 607 .. 575 612 .. 0.74 6 ? 8.3 0.1 0.27 22 10 37 .. 626 654 .. 619 655 .. 0.85 7 ? 7.5 0.1 0.49 39 11 33 .. 669 691 .. 661 696 .. 0.82 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.012 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|F5H7D6|F5H7D6_HUMAN 409 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 440 55.48555799999999999*****.*******9 PP == domain 2 score: 6.2 bits; conditional E-value: 1.3 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|F5H7D6|F5H7D6_HUMAN 461 YIRSCKLLPDGRTLIVGGEASTLTIWD 487 499999********************9 PP == domain 3 score: 11.9 bits; conditional E-value: 0.021 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd tr|F5H7D6|F5H7D6_HUMAN 507 YALAISPDAKVCFSCCSDGNIAVWD 531 68999******887755*******9 PP == domain 4 score: 16.2 bits; conditional E-value: 0.0009 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd tr|F5H7D6|F5H7D6_HUMAN 537 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 573 6899****77799***9999999747999*******9 PP == domain 5 score: 6.0 bits; conditional E-value: 1.5 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ tr|F5H7D6|F5H7D6_HUMAN 580 LQQHdfTSqIFSLGYCPTGEWLAVGMES 607 566753226**************99755 PP == domain 6 score: 8.3 bits; conditional E-value: 0.27 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W tr|F5H7D6|F5H7D6_HUMAN 626 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 654 7778**************99999987766 PP == domain 7 score: 7.5 bits; conditional E-value: 0.49 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|F5H7D6|F5H7D6_HUMAN 669 SSVLSCDISADDKYIVTGSGDKK 691 4599**************87986 PP >> sp|Q92466|DDB2_HUMAN DNA damage-binding protein 2 OS=Homo sapiens GN=DDB2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.19 16 14 38 .] 115 140 .. 102 140 .. 0.93 2 ! 26.5 0.2 4.7e-07 3.8e-05 2 38 .] 233 271 .. 232 271 .. 0.89 3 ? 11.6 0.0 0.024 2 10 37 .. 287 315 .. 280 316 .. 0.84 4 ? 6.9 0.0 0.76 62 12 38 .] 393 419 .. 371 419 .. 0.85 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.19 EEEEEETTSSE.EEEEETTSEEEEEE CS WD40 14 tslafspdgaw.lasGsdDgtvriWd 38 tsla++p ++ +a Gs+ g +++W+ sp|Q92466|DDB2_HUMAN 115 TSLAWHPTHPStVAVGSKGGDIMLWN 140 89*9*****999889**********8 PP == domain 2 score: 26.5 bits; conditional E-value: 4.7e-07 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + l+ l+ H + vt++a +p +w la++s D+tv+iWd sp|Q92466|DDB2_HUMAN 233 KELWNLRMHkKKVTHVALNPCCDWfLATASVDQTVKIWD 271 67888999*888************55799*********9 PP == domain 3 score: 11.6 bits; conditional E-value: 0.024 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H +v++ +fspdga l++ + + +r++ sp|Q92466|DDB2_HUMAN 287 HrHPVNAACFSPDGARLLTTDQKSEIRVY 315 5448**************99999999997 PP == domain 4 score: 6.9 bits; conditional E-value: 0.76 SEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 12 svtsla.fspdgawlasGsdDgtvriWd 38 +++sl f+p g+ las++ ++ iW+ sp|Q92466|DDB2_HUMAN 393 GISSLNeFNPMGDTLASAM-GYHILIWS 419 4888889********9988.*******5 PP >> tr|H0YNT2|H0YNT2_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 0.012 1 6 38 .] 426 457 .. 421 457 .. 0.83 2 ? 6.1 0.0 1.3 1.1e+02 12 38 .] 478 504 .. 467 504 .. 0.91 3 ? 11.8 0.1 0.021 1.7 14 38 .] 524 548 .. 514 548 .. 0.85 4 ! 16.1 1.3 0.00093 0.075 3 38 .] 554 590 .. 552 590 .. 0.88 5 ? 5.9 0.0 1.5 1.3e+02 7 31 .. 597 624 .. 592 629 .. 0.74 6 ? 8.3 0.1 0.28 23 10 37 .. 643 671 .. 636 672 .. 0.85 7 ? 7.5 0.1 0.5 41 11 33 .. 686 708 .. 678 713 .. 0.82 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.012 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|H0YNT2|H0YNT2_HUMAN 426 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 457 55.48555799999999999*****.*******9 PP == domain 2 score: 6.1 bits; conditional E-value: 1.3 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|H0YNT2|H0YNT2_HUMAN 478 YIRSCKLLPDGRTLIVGGEASTLTIWD 504 499999********************9 PP == domain 3 score: 11.8 bits; conditional E-value: 0.021 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd tr|H0YNT2|H0YNT2_HUMAN 524 YALAISPDAKVCFSCCSDGNIAVWD 548 68999******887755*******9 PP == domain 4 score: 16.1 bits; conditional E-value: 0.00093 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd tr|H0YNT2|H0YNT2_HUMAN 554 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 590 6899****77799***9999999747999*******9 PP == domain 5 score: 5.9 bits; conditional E-value: 1.5 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ tr|H0YNT2|H0YNT2_HUMAN 597 LQQHdfTSqIFSLGYCPTGEWLAVGMES 624 566753226**************99755 PP == domain 6 score: 8.3 bits; conditional E-value: 0.28 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W tr|H0YNT2|H0YNT2_HUMAN 643 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 671 7778**************99999987766 PP == domain 7 score: 7.5 bits; conditional E-value: 0.5 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|H0YNT2|H0YNT2_HUMAN 686 SSVLSCDISADDKYIVTGSGDKK 708 4599**************87986 PP >> tr|F6X3N5|F6X3N5_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Fragment) OS=Homo sapiens G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.0 6.1e-07 4.9e-05 4 38 .] 35 70 .. 32 70 .. 0.94 2 ! 14.8 0.1 0.0024 0.19 12 38 .] 86 112 .. 73 112 .. 0.85 3 ! 20.4 0.2 4.2e-05 0.0034 5 38 .] 124 157 .. 120 157 .. 0.90 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 6.1e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd tr|F6X3N5|F6X3N5_HUMAN 35 RRTLRGHlAKIYAMHWGTDSRLLVSASQDGKLIIWD 70 689****999*************************9 PP == domain 2 score: 14.8 bits; conditional E-value: 0.0024 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ tr|F6X3N5|F6X3N5_HUMAN 86 WVMTCAYAPSGNYVACGGLDNICSIYN 112 488889*******************97 PP == domain 3 score: 20.4 bits; conditional E-value: 4.2e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 r+l GH + ++++f +d++ ++s++ D t+ +Wd tr|F6X3N5|F6X3N5_HUMAN 124 RELAGHtGYLSCCRFLDDNQIVTSSG-DTTCALWD 157 7899**666*************9989.*******9 PP >> sp|Q9HBG6|IF122_HUMAN Intraflagellar transport protein 122 homolog OS=Homo sapiens GN=IFT122 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.83 67 10 34 .. 13 45 .. 4 47 .. 0.77 2 ! 28.2 0.0 1.4e-07 1.1e-05 2 37 .. 44 80 .. 43 81 .. 0.91 3 ? 5.2 0.1 2.5 2.1e+02 9 31 .. 91 113 .. 83 120 .. 0.75 4 ? 6.6 0.0 0.95 77 4 36 .. 123 158 .. 121 160 .. 0.78 5 ? 4.6 0.0 4.1 3.3e+02 9 24 .. 174 190 .. 166 193 .. 0.86 6 ? 10.7 0.1 0.048 3.8 7 37 .. 317 348 .. 311 349 .. 0.79 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.83 SSSEEEEEEETTSSE..EEEEET.......TSEE CS WD40 10 Hssvtslafspdgaw..lasGsd.......Dgtv 34 H +++++af pdg+ la+Gs+ Dgt+ sp|Q9HBG6|IF122_HUMAN 13 H-CINDIAFKPDGTQliLAAGSRllvydtsDGTL 45 6.7************4446898666666667776 PP == domain 2 score: 28.2 bits; conditional E-value: 1.4e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 ++l+ l+GH++ v+++a+ +dg+ +asGs D++v iW sp|Q9HBG6|IF122_HUMAN 44 TLLQPLKGHKDtVYCVAYAKDGKRFASGSADKSVIIW 80 67899****555************************* PP == domain 3 score: 5.2 bits; conditional E-value: 2.5 SSSS.EEEEEEETTSSEEEEEETT CS WD40 9 GHss.vtslafspdgawlasGsdD 31 +H++ + +++++p + las+s sp|Q9HBG6|IF122_HUMAN 91 THNDaIQCVSYNPITHQLASCS-S 113 69556********9999**997.3 PP == domain 4 score: 6.6 bits; conditional E-value: 0.95 EEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ss..vtslafspdgawlasGsdDgtvri 36 +++ + H ss + ++++ dg++la G+ +g + i sp|Q9HBG6|IF122_HUMAN 123 QKSVSKHkSSskIICCSWTNDGQYLALGMFNGIISI 158 56778897447977**********987876777765 PP == domain 5 score: 4.6 bits; conditional E-value: 4.1 SS.SSEEEEEEETTSSE CS WD40 9 GH.ssvtslafspdgaw 24 G s+++s++++p+++w sp|Q9HBG6|IF122_HUMAN 174 GSlSPIWSICWNPSSRW 190 56678***********9 PP == domain 6 score: 10.7 bits; conditional E-value: 0.048 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ sp|Q9HBG6|IF122_HUMAN 317 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 348 444545698888*****************876 PP >> sp|Q9HBG6-2|IF122_HUMAN Isoform 2 of Intraflagellar transport protein 122 homolog OS=Homo sapiens GN=IFT122 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.83 67 10 34 .. 13 45 .. 4 47 .. 0.77 2 ! 28.2 0.0 1.4e-07 1.1e-05 2 37 .. 44 80 .. 43 81 .. 0.91 3 ? 5.2 0.1 2.5 2.1e+02 9 31 .. 91 113 .. 83 120 .. 0.75 4 ? 6.6 0.0 0.96 77 4 36 .. 123 158 .. 121 160 .. 0.78 5 ? 4.6 0.0 4.1 3.3e+02 9 24 .. 174 190 .. 166 193 .. 0.86 6 ? 10.7 0.1 0.048 3.9 7 37 .. 317 348 .. 311 349 .. 0.79 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.83 SSSEEEEEEETTSSE..EEEEET.......TSEE CS WD40 10 Hssvtslafspdgaw..lasGsd.......Dgtv 34 H +++++af pdg+ la+Gs+ Dgt+ sp|Q9HBG6-2|IF122_HUMAN 13 H-CINDIAFKPDGTQliLAAGSRllvydtsDGTL 45 6.7************4446898666666667776 PP == domain 2 score: 28.2 bits; conditional E-value: 1.4e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 ++l+ l+GH++ v+++a+ +dg+ +asGs D++v iW sp|Q9HBG6-2|IF122_HUMAN 44 TLLQPLKGHKDtVYCVAYAKDGKRFASGSADKSVIIW 80 67899****555************************* PP == domain 3 score: 5.2 bits; conditional E-value: 2.5 SSSS.EEEEEEETTSSEEEEEETT CS WD40 9 GHss.vtslafspdgawlasGsdD 31 +H++ + +++++p + las+s sp|Q9HBG6-2|IF122_HUMAN 91 THNDaIQCVSYNPITHQLASCS-S 113 69556********9999**997.3 PP == domain 4 score: 6.6 bits; conditional E-value: 0.96 EEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ss..vtslafspdgawlasGsdDgtvri 36 +++ + H ss + ++++ dg++la G+ +g + i sp|Q9HBG6-2|IF122_HUMAN 123 QKSVSKHkSSskIICCSWTNDGQYLALGMFNGIISI 158 56778897447977**********987876777765 PP == domain 5 score: 4.6 bits; conditional E-value: 4.1 SS.SSEEEEEEETTSSE CS WD40 9 GH.ssvtslafspdgaw 24 G s+++s++++p+++w sp|Q9HBG6-2|IF122_HUMAN 174 GSlSPIWSICWNPSSRW 190 56678***********9 PP == domain 6 score: 10.7 bits; conditional E-value: 0.048 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ sp|Q9HBG6-2|IF122_HUMAN 317 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 348 444545698888*****************876 PP >> tr|D6R997|D6R997_HUMAN Coatomer subunit beta' (Fragment) OS=Homo sapiens GN=COPB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 0.003 0.24 8 38 .] 12 43 .. 6 43 .. 0.82 2 ? 12.3 0.0 0.015 1.2 13 38 .] 60 85 .. 47 85 .. 0.80 3 ! 24.3 0.2 2.4e-06 0.0002 4 37 .. 92 149 .. 89 150 .. 0.66 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 0.003 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 t+ s+ v s++ +p +w++++ ++g+v +W+ tr|D6R997|D6R997_HUMAN 12 TARSDrVKSVDLHPTEPWMLASLYNGSVCVWN 43 55544599***********99967*******8 PP == domain 2 score: 12.3 bits; conditional E-value: 0.015 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v++ +f ++w+++G dD +r+++ tr|D6R997|D6R997_HUMAN 60 VRAAKFVARKNWVVTGADDMQIRVFN 85 7777789999**************97 PP == domain 3 score: 24.3 bits; conditional E-value: 2.4e-06 EEEEESSSS.EEEEEEETTSSE.......................EEEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgaw.......................lasGsdDgtvriW 37 ++ +++Hs+ ++++a++p +++ +as+s D+t+++W tr|D6R997|D6R997_HUMAN 92 VHMFEAHSDyIRCIAVHPTQPFiltssghthyvmqivinpkdnnqFASASLDRTIKVW 149 799****556*****999999944444444444444444444444555777******* PP >> tr|E9PMG4|E9PMG4_HUMAN Telomerase Cajal body protein 1 OS=Homo sapiens GN=WRAP53 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 8.4 6.8e+02 19 38 .] 145 164 .. 142 164 .. 0.88 2 ! 15.3 0.0 0.0017 0.14 14 37 .. 248 270 .. 230 271 .. 0.83 3 ? 7.6 0.0 0.47 38 9 32 .. 290 314 .. 282 322 .. 0.79 4 ! 22.1 0.1 1.2e-05 0.00094 2 38 .] 325 363 .. 324 363 .. 0.87 5 ? 11.3 0.1 0.03 2.5 15 38 .] 387 408 .. 372 408 .. 0.84 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.4 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 pdg+ +++ s D+ +ri++ tr|E9PMG4|E9PMG4_HUMAN 145 APDGSCILTNSADNILRIYN 164 699999999888******98 PP == domain 2 score: 15.3 bits; conditional E-value: 0.0017 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 +sl+fspdg+ l++G ++tvr++ tr|E9PMG4|E9PMG4_HUMAN 248 HSLCFSPDGSQLFCGF-NRTVRVF 270 69***********999.*****97 PP == domain 3 score: 7.6 bits; conditional E-value: 0.47 SSSS.EEEEEEETTSSEEEEEETTS CS WD40 9 GHss.vtslafspdgawlasGsdDg 32 G+s+ ++++afsp +++ a+Gs+ + tr|E9PMG4|E9PMG4_HUMAN 290 GQSGiISCIAFSPAQPLYACGSYGR 314 675557***********99999555 PP == domain 4 score: 22.1 bits; conditional E-value: 1.2e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs.dDgtvriWd 38 ++l l GH +++t+l+f+pdg+ ++sG +D + Wd tr|E9PMG4|E9PMG4_HUMAN 325 SPLALLGGHqGGITHLCFHPDGNRFFSGArKDAELLCWD 363 6788899**888****************74699999998 PP == domain 5 score: 11.3 bits; conditional E-value: 0.03 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 + +p g++l+sGs g v +Wd tr|E9PMG4|E9PMG4_HUMAN 387 D--LDPTGQFLVSGSTSGAVSVWD 408 3..59******************9 PP >> tr|H0YIE8|H0YIE8_HUMAN WD repeat domain-containing protein 83 (Fragment) OS=Homo sapiens GN=WDR83 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.1 5.6e-07 4.6e-05 1 38 [] 2 40 .. 2 40 .. 0.94 2 ? 12.5 0.1 0.013 1 5 36 .. 119 149 .. 115 151 .. 0.78 3 ! 20.0 0.0 5.4e-05 0.0044 1 38 [] 155 195 .. 155 195 .. 0.82 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 5.6e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq +r+++GH + v+ ++f+ + + ++sGs D ++r Wd tr|H0YIE8|H0YIE8_HUMAN 2 GQVVRKFRGHaGKVNTVQFNEEATVILSGSIDSSIRCWD 40 6889******777*************************9 PP == domain 2 score: 12.5 bits; conditional E-value: 0.013 EEEESSSSEEEEEEETTSSE.EEEEETTSEEEE CS WD40 5 rtltGHssvtslafspdgaw.lasGsdDgtvri 36 + G ++t+ +fs+dg+ l+ +s D t+r+ tr|H0YIE8|H0YIE8_HUMAN 119 SDYVGS-PITCTCFSRDGQCtLV-SSLDSTLRL 149 456666.8************766.566****98 PP == domain 3 score: 20.0 bits; conditional E-value: 5.4e-05 TEEEEEEESS.SS...E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ss...v.tslafspdgawlasGsdDgtvriWd 38 g++l++++GH + ++ s + ++s+s+Dg+v +Wd tr|H0YIE8|H0YIE8_HUMAN 155 GELLGEYKGHkNQeykLdCC--LSERDTHVVSCSEDGKVFFWD 195 57899*****6558988444..4888888899**********9 PP >> sp|Q04726-2|TLE3_HUMAN Isoform 2 of Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 0.013 1.1 6 38 .] 470 501 .. 465 501 .. 0.83 2 ? 6.0 0.0 1.4 1.2e+02 12 38 .] 522 548 .. 511 548 .. 0.91 3 ? 11.7 0.1 0.023 1.8 14 38 .] 568 592 .. 558 592 .. 0.85 4 ! 16.0 1.3 0.00099 0.081 3 38 .] 598 634 .. 596 634 .. 0.88 5 ? 5.8 0.0 1.7 1.3e+02 7 31 .. 641 668 .. 636 673 .. 0.74 6 ? 8.2 0.1 0.3 24 10 37 .. 687 715 .. 680 716 .. 0.85 7 ? 7.4 0.1 0.54 43 11 33 .. 730 752 .. 722 757 .. 0.82 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd sp|Q04726-2|TLE3_HUMAN 470 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 501 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.4 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04726-2|TLE3_HUMAN 522 YIRSCKLLPDGRTLIVGGEASTLTIWD 548 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd sp|Q04726-2|TLE3_HUMAN 568 YALAISPDAKVCFSCCSDGNIAVWD 592 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.00099 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd sp|Q04726-2|TLE3_HUMAN 598 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 634 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ sp|Q04726-2|TLE3_HUMAN 641 LQQHdfTSqIFSLGYCPTGEWLAVGMES 668 556753226**************99755 PP == domain 6 score: 8.2 bits; conditional E-value: 0.3 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W sp|Q04726-2|TLE3_HUMAN 687 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 715 7778**************99999987766 PP == domain 7 score: 7.4 bits; conditional E-value: 0.54 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ sp|Q04726-2|TLE3_HUMAN 730 SSVLSCDISADDKYIVTGSGDKK 752 4599**************87986 PP >> tr|F8W964|F8W964_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 0.013 1.1 6 38 .] 472 503 .. 467 503 .. 0.83 2 ? 6.0 0.0 1.4 1.2e+02 12 38 .] 524 550 .. 513 550 .. 0.91 3 ? 11.7 0.1 0.023 1.8 14 38 .] 570 594 .. 560 594 .. 0.85 4 ! 16.0 1.3 0.001 0.081 3 38 .] 600 636 .. 598 636 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 643 670 .. 638 675 .. 0.74 6 ? 8.2 0.1 0.3 25 10 37 .. 689 717 .. 682 718 .. 0.85 7 ? 7.4 0.1 0.54 44 11 33 .. 732 754 .. 724 759 .. 0.82 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|F8W964|F8W964_HUMAN 472 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 503 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.4 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|F8W964|F8W964_HUMAN 524 YIRSCKLLPDGRTLIVGGEASTLTIWD 550 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd tr|F8W964|F8W964_HUMAN 570 YALAISPDAKVCFSCCSDGNIAVWD 594 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd tr|F8W964|F8W964_HUMAN 600 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 636 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ tr|F8W964|F8W964_HUMAN 643 LQQHdfTSqIFSLGYCPTGEWLAVGMES 670 556753226**************99755 PP == domain 6 score: 8.2 bits; conditional E-value: 0.3 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W tr|F8W964|F8W964_HUMAN 689 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 717 7778**************99999987766 PP == domain 7 score: 7.4 bits; conditional E-value: 0.54 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|F8W964|F8W964_HUMAN 732 SSVLSCDISADDKYIVTGSGDKK 754 4599**************87986 PP >> tr|F8W8S3|F8W8S3_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.013 1.1 6 38 .] 474 505 .. 469 505 .. 0.83 2 ? 6.0 0.0 1.4 1.2e+02 12 38 .] 526 552 .. 515 552 .. 0.91 3 ? 11.7 0.1 0.023 1.8 14 38 .] 572 596 .. 562 596 .. 0.85 4 ! 16.0 1.3 0.001 0.081 3 38 .] 602 638 .. 600 638 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 645 672 .. 640 677 .. 0.74 6 ? 8.2 0.1 0.3 25 10 37 .. 691 719 .. 684 720 .. 0.85 7 ? 7.4 0.1 0.54 44 11 33 .. 734 756 .. 726 761 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.013 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|F8W8S3|F8W8S3_HUMAN 474 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 505 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.4 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|F8W8S3|F8W8S3_HUMAN 526 YIRSCKLLPDGRTLIVGGEASTLTIWD 552 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd tr|F8W8S3|F8W8S3_HUMAN 572 YALAISPDAKVCFSCCSDGNIAVWD 596 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd tr|F8W8S3|F8W8S3_HUMAN 602 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 638 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ tr|F8W8S3|F8W8S3_HUMAN 645 LQQHdfTSqIFSLGYCPTGEWLAVGMES 672 556753226**************99755 PP == domain 6 score: 8.2 bits; conditional E-value: 0.3 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W tr|F8W8S3|F8W8S3_HUMAN 691 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 719 7778**************99999987766 PP == domain 7 score: 7.4 bits; conditional E-value: 0.54 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|F8W8S3|F8W8S3_HUMAN 734 SSVLSCDISADDKYIVTGSGDKK 756 4599**************87986 PP >> sp|Q04726-3|TLE3_HUMAN Isoform 3 of Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.013 1.1 6 38 .] 474 505 .. 469 505 .. 0.83 2 ? 6.0 0.0 1.4 1.2e+02 12 38 .] 526 552 .. 515 552 .. 0.91 3 ? 11.7 0.1 0.023 1.8 14 38 .] 572 596 .. 562 596 .. 0.85 4 ! 16.0 1.3 0.001 0.081 3 38 .] 602 638 .. 600 638 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 645 672 .. 640 677 .. 0.74 6 ? 8.2 0.1 0.3 25 10 37 .. 691 719 .. 684 720 .. 0.85 7 ? 7.4 0.1 0.54 44 11 33 .. 734 756 .. 726 761 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.013 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd sp|Q04726-3|TLE3_HUMAN 474 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 505 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.4 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04726-3|TLE3_HUMAN 526 YIRSCKLLPDGRTLIVGGEASTLTIWD 552 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd sp|Q04726-3|TLE3_HUMAN 572 YALAISPDAKVCFSCCSDGNIAVWD 596 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd sp|Q04726-3|TLE3_HUMAN 602 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 638 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ sp|Q04726-3|TLE3_HUMAN 645 LQQHdfTSqIFSLGYCPTGEWLAVGMES 672 556753226**************99755 PP == domain 6 score: 8.2 bits; conditional E-value: 0.3 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W sp|Q04726-3|TLE3_HUMAN 691 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 719 7778**************99999987766 PP == domain 7 score: 7.4 bits; conditional E-value: 0.54 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ sp|Q04726-3|TLE3_HUMAN 734 SSVLSCDISADDKYIVTGSGDKK 756 4599**************87986 PP >> tr|D6R909|D6R909_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.0 3e-05 0.0024 4 38 .] 8 44 .. 5 44 .. 0.87 2 ! 38.0 0.6 1.1e-10 9e-09 3 38 .] 55 91 .. 53 91 .. 0.93 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 3e-05 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s+s+D+t+ +W+ tr|D6R909|D6R909_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRDKTIIMWK 44 5799***666****99888888899***********6 PP == domain 2 score: 38.0 bits; conditional E-value: 1.1e-10 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r l+GHs+ v+++ s+dg++ +sGs+Dgt+r+Wd tr|D6R909|D6R909_HUMAN 55 PQRALRGHSHfVSDVVISSDGQFALSGSWDGTLRLWD 91 7899****667************99***********9 PP >> tr|Q6PI57|Q6PI57_HUMAN TLE3 protein OS=Homo sapiens GN=TLE3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.014 1.1 6 38 .] 477 508 .. 472 508 .. 0.83 2 ? 6.0 0.0 1.5 1.2e+02 12 38 .] 529 555 .. 518 555 .. 0.91 3 ? 11.7 0.1 0.023 1.9 14 38 .] 575 599 .. 565 599 .. 0.85 4 ! 16.0 1.3 0.001 0.082 3 38 .] 605 641 .. 603 641 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 648 675 .. 643 680 .. 0.74 6 ? 8.2 0.1 0.3 25 10 37 .. 694 722 .. 687 723 .. 0.85 7 ? 7.4 0.1 0.54 44 11 33 .. 737 759 .. 729 764 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|Q6PI57|Q6PI57_HUMAN 477 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 508 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|Q6PI57|Q6PI57_HUMAN 529 YIRSCKLLPDGRTLIVGGEASTLTIWD 555 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd tr|Q6PI57|Q6PI57_HUMAN 575 YALAISPDAKVCFSCCSDGNIAVWD 599 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd tr|Q6PI57|Q6PI57_HUMAN 605 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 641 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ tr|Q6PI57|Q6PI57_HUMAN 648 LQQHdfTSqIFSLGYCPTGEWLAVGMES 675 556753226**************99755 PP == domain 6 score: 8.2 bits; conditional E-value: 0.3 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W tr|Q6PI57|Q6PI57_HUMAN 694 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 722 7778**************99999987766 PP == domain 7 score: 7.4 bits; conditional E-value: 0.54 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|Q6PI57|Q6PI57_HUMAN 737 SSVLSCDISADDKYIVTGSGDKK 759 4599**************87986 PP >> sp|Q04726-5|TLE3_HUMAN Isoform 5 of Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.014 1.1 6 38 .] 479 510 .. 474 510 .. 0.83 2 ? 6.0 0.0 1.5 1.2e+02 12 38 .] 531 557 .. 520 557 .. 0.91 3 ? 11.7 0.1 0.023 1.9 14 38 .] 577 601 .. 567 601 .. 0.85 4 ! 16.0 1.3 0.001 0.082 3 38 .] 607 643 .. 605 643 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 650 677 .. 645 682 .. 0.74 6 ? 8.2 0.1 0.31 25 10 37 .. 696 724 .. 689 725 .. 0.85 7 ? 7.4 0.1 0.54 44 11 33 .. 739 761 .. 731 766 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd sp|Q04726-5|TLE3_HUMAN 479 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 510 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04726-5|TLE3_HUMAN 531 YIRSCKLLPDGRTLIVGGEASTLTIWD 557 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd sp|Q04726-5|TLE3_HUMAN 577 YALAISPDAKVCFSCCSDGNIAVWD 601 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd sp|Q04726-5|TLE3_HUMAN 607 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 643 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ sp|Q04726-5|TLE3_HUMAN 650 LQQHdfTSqIFSLGYCPTGEWLAVGMES 677 556753226**************99755 PP == domain 6 score: 8.2 bits; conditional E-value: 0.31 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W sp|Q04726-5|TLE3_HUMAN 696 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 724 7778**************99999987766 PP == domain 7 score: 7.4 bits; conditional E-value: 0.54 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ sp|Q04726-5|TLE3_HUMAN 739 SSVLSCDISADDKYIVTGSGDKK 761 4599**************87986 PP >> sp|Q04726-4|TLE3_HUMAN Isoform 4 of Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.014 1.1 6 38 .] 482 513 .. 477 513 .. 0.83 2 ? 6.0 0.0 1.5 1.2e+02 12 38 .] 534 560 .. 523 560 .. 0.91 3 ? 11.7 0.1 0.023 1.9 14 38 .] 580 604 .. 570 604 .. 0.85 4 ! 16.0 1.3 0.001 0.082 3 38 .] 610 646 .. 608 646 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 653 680 .. 648 685 .. 0.74 6 ? 8.1 0.1 0.31 25 10 37 .. 699 727 .. 692 728 .. 0.85 7 ? 7.4 0.1 0.55 44 11 33 .. 742 764 .. 734 769 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd sp|Q04726-4|TLE3_HUMAN 482 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 513 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04726-4|TLE3_HUMAN 534 YIRSCKLLPDGRTLIVGGEASTLTIWD 560 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd sp|Q04726-4|TLE3_HUMAN 580 YALAISPDAKVCFSCCSDGNIAVWD 604 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd sp|Q04726-4|TLE3_HUMAN 610 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 646 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ sp|Q04726-4|TLE3_HUMAN 653 LQQHdfTSqIFSLGYCPTGEWLAVGMES 680 556753226**************99755 PP == domain 6 score: 8.1 bits; conditional E-value: 0.31 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W sp|Q04726-4|TLE3_HUMAN 699 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 727 7778**************99999987766 PP == domain 7 score: 7.4 bits; conditional E-value: 0.55 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ sp|Q04726-4|TLE3_HUMAN 742 SSVLSCDISADDKYIVTGSGDKK 764 4599**************87986 PP >> sp|Q04726|TLE3_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.014 1.1 6 38 .] 482 513 .. 477 513 .. 0.83 2 ? 6.0 0.0 1.5 1.2e+02 12 38 .] 534 560 .. 523 560 .. 0.91 3 ? 11.7 0.1 0.023 1.9 14 38 .] 580 604 .. 570 604 .. 0.85 4 ! 16.0 1.3 0.001 0.082 3 38 .] 610 646 .. 608 646 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 653 680 .. 648 685 .. 0.74 6 ? 8.1 0.1 0.31 25 10 37 .. 699 727 .. 692 728 .. 0.85 7 ? 7.4 0.1 0.55 44 11 33 .. 742 764 .. 734 769 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd sp|Q04726|TLE3_HUMAN 482 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 513 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04726|TLE3_HUMAN 534 YIRSCKLLPDGRTLIVGGEASTLTIWD 560 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd sp|Q04726|TLE3_HUMAN 580 YALAISPDAKVCFSCCSDGNIAVWD 604 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd sp|Q04726|TLE3_HUMAN 610 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 646 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ sp|Q04726|TLE3_HUMAN 653 LQQHdfTSqIFSLGYCPTGEWLAVGMES 680 556753226**************99755 PP == domain 6 score: 8.1 bits; conditional E-value: 0.31 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W sp|Q04726|TLE3_HUMAN 699 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 727 7778**************99999987766 PP == domain 7 score: 7.4 bits; conditional E-value: 0.55 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ sp|Q04726|TLE3_HUMAN 742 SSVLSCDISADDKYIVTGSGDKK 764 4599**************87986 PP >> tr|H0YKT5|H0YKT5_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.014 1.1 6 38 .] 484 515 .. 479 515 .. 0.83 2 ? 6.0 0.0 1.5 1.2e+02 12 38 .] 536 562 .. 525 562 .. 0.91 3 ? 11.7 0.1 0.023 1.9 14 38 .] 582 606 .. 572 606 .. 0.85 4 ! 16.0 1.3 0.001 0.082 3 38 .] 612 648 .. 610 648 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 655 682 .. 650 687 .. 0.74 6 ? 8.1 0.1 0.31 25 10 37 .. 701 729 .. 694 730 .. 0.85 7 ? 7.4 0.1 0.55 44 11 33 .. 744 766 .. 736 771 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|H0YKT5|H0YKT5_HUMAN 484 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 515 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|H0YKT5|H0YKT5_HUMAN 536 YIRSCKLLPDGRTLIVGGEASTLTIWD 562 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd tr|H0YKT5|H0YKT5_HUMAN 582 YALAISPDAKVCFSCCSDGNIAVWD 606 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd tr|H0YKT5|H0YKT5_HUMAN 612 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 648 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ tr|H0YKT5|H0YKT5_HUMAN 655 LQQHdfTSqIFSLGYCPTGEWLAVGMES 682 556753226**************99755 PP == domain 6 score: 8.1 bits; conditional E-value: 0.31 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W tr|H0YKT5|H0YKT5_HUMAN 701 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 729 7778**************99999987766 PP == domain 7 score: 7.4 bits; conditional E-value: 0.55 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|H0YKT5|H0YKT5_HUMAN 744 SSVLSCDISADDKYIVTGSGDKK 766 4599**************87986 PP >> tr|H0YKN8|H0YKN8_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.014 1.1 6 38 .] 488 519 .. 483 519 .. 0.83 2 ? 6.0 0.0 1.5 1.2e+02 12 38 .] 540 566 .. 529 566 .. 0.91 3 ? 11.7 0.1 0.023 1.9 14 38 .] 586 610 .. 576 610 .. 0.85 4 ! 16.0 1.3 0.001 0.083 3 38 .] 616 652 .. 614 652 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 659 686 .. 654 691 .. 0.74 6 ? 8.1 0.1 0.31 25 10 37 .. 705 733 .. 698 734 .. 0.85 7 ? 7.3 0.1 0.55 45 11 33 .. 748 770 .. 740 775 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|H0YKN8|H0YKN8_HUMAN 488 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 519 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|H0YKN8|H0YKN8_HUMAN 540 YIRSCKLLPDGRTLIVGGEASTLTIWD 566 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd tr|H0YKN8|H0YKN8_HUMAN 586 YALAISPDAKVCFSCCSDGNIAVWD 610 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd tr|H0YKN8|H0YKN8_HUMAN 616 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 652 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ tr|H0YKN8|H0YKN8_HUMAN 659 LQQHdfTSqIFSLGYCPTGEWLAVGMES 686 556753226**************99755 PP == domain 6 score: 8.1 bits; conditional E-value: 0.31 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W tr|H0YKN8|H0YKN8_HUMAN 705 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 733 7778**************99999987766 PP == domain 7 score: 7.3 bits; conditional E-value: 0.55 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|H0YKN8|H0YKN8_HUMAN 748 SSVLSCDISADDKYIVTGSGDKK 770 4599**************87986 PP >> tr|H0YL70|H0YL70_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.014 1.1 6 38 .] 492 523 .. 487 523 .. 0.83 2 ? 6.0 0.0 1.5 1.2e+02 12 38 .] 544 570 .. 533 570 .. 0.91 3 ? 11.7 0.1 0.023 1.9 14 38 .] 590 614 .. 580 614 .. 0.85 4 ! 16.0 1.3 0.001 0.083 3 38 .] 620 656 .. 618 656 .. 0.88 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 663 690 .. 658 695 .. 0.74 6 ? 8.1 0.1 0.31 25 10 37 .. 709 737 .. 702 738 .. 0.85 7 ? 7.3 0.1 0.56 45 11 33 .. 752 774 .. 744 779 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|H0YL70|H0YL70_HUMAN 492 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 523 55.48555799999999999*****.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|H0YL70|H0YL70_HUMAN 544 YIRSCKLLPDGRTLIVGGEASTLTIWD 570 499999********************9 PP == domain 3 score: 11.7 bits; conditional E-value: 0.023 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd + +s++ Dg++ +Wd tr|H0YL70|H0YL70_HUMAN 590 YALAISPDAKVCFSCCSDGNIAVWD 614 68999******887755*******9 PP == domain 4 score: 16.0 bits; conditional E-value: 0.001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s+dg+ l +G+ D+tvr Wd tr|H0YL70|H0YL70_HUMAN 620 LVRQFQGHtDGASCIDISHDGTKLWTGGLDNTVRSWD 656 6899****77799***9999999747999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ tr|H0YL70|H0YL70_HUMAN 663 LQQHdfTSqIFSLGYCPTGEWLAVGMES 690 556753226**************99755 PP == domain 6 score: 8.1 bits; conditional E-value: 0.31 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W tr|H0YL70|H0YL70_HUMAN 709 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 737 7778**************99999987766 PP == domain 7 score: 7.3 bits; conditional E-value: 0.56 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ tr|H0YL70|H0YL70_HUMAN 752 SSVLSCDISADDKYIVTGSGDKK 774 4599**************87986 PP >> sp|Q04724|TLE1_HUMAN Transducin-like enhancer protein 1 OS=Homo sapiens GN=TLE1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.039 3.2 10 38 .] 483 511 .. 475 511 .. 0.83 2 ? 6.8 0.0 0.84 68 12 38 .] 532 558 .. 515 558 .. 0.89 3 ? 12.8 0.2 0.01 0.82 14 38 .] 578 602 .. 568 602 .. 0.85 4 ! 16.1 0.8 0.00096 0.078 3 38 .] 608 644 .. 606 644 .. 0.86 5 ? 5.8 0.0 1.7 1.4e+02 7 31 .. 651 678 .. 646 683 .. 0.74 6 ? 8.1 0.1 0.32 26 10 37 .. 697 725 .. 691 726 .. 0.85 7 ? 6.4 0.1 1.1 86 11 33 .. 740 762 .. 732 767 .. 0.82 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.039 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H+ v+++ s + + +G+ +g v++Wd sp|Q04724|TLE1_HUMAN 483 HGEvVCAVTISNPTRHVYTGG-KGCVKVWD 511 7555799999999999*****.*******9 PP == domain 2 score: 6.8 bits; conditional E-value: 0.84 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg l+ G++ t+ iWd sp|Q04724|TLE1_HUMAN 532 YIRSCKLLPDGCTLIVGGEASTLSIWD 558 489999********************9 PP == domain 3 score: 12.8 bits; conditional E-value: 0.01 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la spd++ +s++ Dg++ +Wd sp|Q04724|TLE1_HUMAN 578 YALAISPDSKVCFSCCSDGNIAVWD 602 6899*******887755*******9 PP == domain 4 score: 16.1 bits; conditional E-value: 0.00096 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++r + GH ++ ++++ s dg+ l +G+ D+tvr Wd sp|Q04724|TLE1_HUMAN 608 LVRQFQGHtDGASCIDISNDGTKLWTGGLDNTVRSWD 644 6899****777999999999999647999*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EESS..SS.EEEEEEETTSSEEEEEETT CS WD40 7 ltGH..ss.vtslafspdgawlasGsdD 31 l H +s + sl ++p g wla G++ sp|Q04724|TLE1_HUMAN 651 LQQHdfTSqIFSLGYCPTGEWLAVGMES 678 556753226**************99755 PP == domain 6 score: 8.1 bits; conditional E-value: 0.32 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H s+v sl+f g+w++s ++D+ + W sp|Q04724|TLE1_HUMAN 697 HeSCVLSLKFAYCGKWFVSTGKDNLLNAW 725 7778**************99999987766 PP == domain 7 score: 6.4 bits; conditional E-value: 1.1 SSEEEEEEETTSSEEEEEETTSE CS WD40 11 ssvtslafspdgawlasGsdDgt 33 ssv s++ s d +++++Gs D++ sp|Q04724|TLE1_HUMAN 740 SSVLSCDISVDDKYIVTGSGDKK 762 45999*************87986 PP >> tr|C9JTS3|C9JTS3_HUMAN Angio-associated migratory cell protein (Fragment) OS=Homo sapiens GN=AAMP PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 0.019 1.5 10 37 .. 44 73 .. 37 74 .. 0.87 2 ! 24.7 0.1 1.9e-06 0.00015 2 37 .. 79 115 .. 78 116 .. 0.91 3 ? 5.4 0.1 2.2 1.8e+02 17 38 .] 135 156 .. 119 156 .. 0.77 4 ! 17.4 0.0 0.00037 0.03 14 38 .] 173 197 .. 162 197 .. 0.79 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.019 S.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 10 H.ssvtslafspdgawla.sGsdDgtvriW 37 H sv +++ +p + la +G++D + +W tr|C9JTS3|C9JTS3_HUMAN 44 HsASVFCVSLDPKTNTLAvTGGEDDKAFVW 73 8667************9769******9999 PP == domain 2 score: 24.7 bits; conditional E-value: 1.9e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l ++ GH +svt+ fs+d++++a+G++ g +++W tr|C9JTS3|C9JTS3_HUMAN 79 ELLFECAGHkDSVTCAGFSHDSTLVATGDMSGLLKVW 115 6788899**777****************99******* PP == domain 3 score: 5.4 bits; conditional E-value: 2.2 EEETTSSEEEEEETTSEEEEEE CS WD40 17 afspdgawlasGsdDgtvriWd 38 ++p + l++G+ Dg+ +W+ tr|C9JTS3|C9JTS3_HUMAN 135 EWHPRAPVLLAGTADGNTWMWK 156 399*********99**999995 PP == domain 4 score: 17.4 bits; conditional E-value: 0.00037 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 t+ ++ pdg+ + G +Dgt+riWd tr|C9JTS3|C9JTS3_HUMAN 173 TCGRVLPDGKRAVVGYEDGTIRIWD 197 5555789****999**********9 PP >> sp|Q9HBG6-3|IF122_HUMAN Isoform 3 of Intraflagellar transport protein 122 homolog OS=Homo sapiens GN=IFT122 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.78 63 10 34 .. 13 45 .. 4 47 .. 0.77 2 ! 28.3 0.0 1.3e-07 1e-05 2 37 .. 44 80 .. 43 81 .. 0.91 3 ? 5.3 0.1 2.4 2e+02 9 31 .. 91 113 .. 83 120 .. 0.75 4 ? 6.7 0.0 0.9 73 4 36 .. 123 158 .. 121 160 .. 0.78 5 ? 10.8 0.1 0.045 3.6 7 37 .. 258 289 .. 252 290 .. 0.79 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.78 SSSEEEEEEETTSSE..EEEEET.......TSEE CS WD40 10 Hssvtslafspdgaw..lasGsd.......Dgtv 34 H +++++af pdg+ la+Gs+ Dgt+ sp|Q9HBG6-3|IF122_HUMAN 13 H-CINDIAFKPDGTQliLAAGSRllvydtsDGTL 45 6.7************4446898666666667776 PP == domain 2 score: 28.3 bits; conditional E-value: 1.3e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 ++l+ l+GH++ v+++a+ +dg+ +asGs D++v iW sp|Q9HBG6-3|IF122_HUMAN 44 TLLQPLKGHKDtVYCVAYAKDGKRFASGSADKSVIIW 80 67899****555************************* PP == domain 3 score: 5.3 bits; conditional E-value: 2.4 SSSS.EEEEEEETTSSEEEEEETT CS WD40 9 GHss.vtslafspdgawlasGsdD 31 +H++ + +++++p + las+s sp|Q9HBG6-3|IF122_HUMAN 91 THNDaIQCVSYNPITHQLASCS-S 113 69556********9999**997.3 PP == domain 4 score: 6.7 bits; conditional E-value: 0.9 EEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ss..vtslafspdgawlasGsdDgtvri 36 +++ + H ss + ++++ dg++la G+ +g + i sp|Q9HBG6-3|IF122_HUMAN 123 QKSVSKHkSSskIICCSWTNDGQYLALGMFNGIISI 158 56778897447977**********987876877765 PP == domain 5 score: 10.8 bits; conditional E-value: 0.045 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ sp|Q9HBG6-3|IF122_HUMAN 258 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 289 444545698888*****************876 PP >> sp|P43034-2|LIS1_HUMAN Isoform 2 of Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens GN=P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.1 5.6e-05 0.0045 7 38 .] 51 88 .. 47 88 .. 0.88 2 ! 34.8 0.1 1.2e-09 9.4e-08 2 37 .. 93 129 .. 92 130 .. 0.93 3 ? 4.0 0.0 6.2 5e+02 2 11 .. 135 145 .. 134 147 .] 0.80 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 5.6e-05 EESS.SSEEEEEEETTSSEEEEEET.....TSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsd.....DgtvriWd 38 l+GH s+vt + f+p + ++s+s+ D t+++Wd sp|P43034-2|LIS1_HUMAN 51 LSGHrSPVTRVIFHPVFSVMVSASEdatikDMTIKLWD 88 89**999**************999556777*******9 PP == domain 2 score: 34.8 bits; conditional E-value: 1.2e-09 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +c+rt GH++ v+s+a p+g+ ++s+s+D+t+++W sp|P43034-2|LIS1_HUMAN 93 ECIRTMHGHDHnVSSVAIMPNGDHIVSASRDKTIKMW 129 8********556************************* PP == domain 3 score: 4.0 bits; conditional E-value: 6.2 EEEEEEESS.S CS WD40 2 qclrtltGH.s 11 c++t+tGH sp|P43034-2|LIS1_HUMAN 135 YCVKTFTGHrE 145 69*******55 PP >> sp|Q6QEF8-5|CORO6_HUMAN Isoform 5 of Coronin-6 OS=Homo sapiens GN=CORO6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.2 4.7e-06 0.00038 8 37 .. 78 109 .. 72 110 .. 0.86 2 ! 17.0 0.1 0.00048 0.039 2 38 .] 122 160 .. 121 160 .. 0.84 3 ! 19.1 0.2 0.00011 0.0088 10 38 .] 174 203 .. 165 203 .. 0.87 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 4.7e-06 ESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawla.sGsdDgtvriW 37 tGH +v +++++p+++ ++ s+sdD t+++W sp|Q6QEF8-5|CORO6_HUMAN 78 TGHtAPVLDIDWCPHNDNVIaSASDDTTIMVW 109 7**888************762679******** PP == domain 2 score: 17.0 bits; conditional E-value: 0.00048 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v l+++p + l++G+ D+ + iW+ sp|Q6QEF8-5|CORO6_HUMAN 122 EPIITLEGHsKRVGILSWHPTARNvlLSAGG-DNVIIIWN 160 57899****888*9999*******4334778.*******8 PP == domain 3 score: 19.1 bits; conditional E-value: 0.00011 SSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriWd 38 H + ++s++++++g++la+ ++D+t+ri d sp|Q6QEF8-5|CORO6_HUMAN 174 H-PdvIHSVCWNSNGSLLATTCKDKTLRIID 203 6.3347*************99*******966 PP >> tr|J3QLV6|J3QLV6_HUMAN Coronin OS=Homo sapiens GN=CORO6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.2 4.2e-06 0.00034 8 37 .. 78 109 .. 72 110 .. 0.86 2 ! 17.2 0.1 0.00043 0.035 2 38 .] 122 160 .. 121 160 .. 0.84 3 ! 19.2 0.2 9.7e-05 0.0079 10 38 .] 174 203 .. 165 203 .. 0.87 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 4.2e-06 ESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawla.sGsdDgtvriW 37 tGH +v +++++p+++ ++ s+sdD t+++W tr|J3QLV6|J3QLV6_HUMAN 78 TGHtAPVLDIDWCPHNDNVIaSASDDTTIMVW 109 7**888************762679******** PP == domain 2 score: 17.2 bits; conditional E-value: 0.00043 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v l+++p + l++G+ D+ + iW+ tr|J3QLV6|J3QLV6_HUMAN 122 EPIITLEGHsKRVGILSWHPTARNvlLSAGG-DNVIIIWN 160 57899****888*9999*******4334778.*******8 PP == domain 3 score: 19.2 bits; conditional E-value: 9.7e-05 SSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriWd 38 H + ++s++++++g++la+ ++D+t+ri d tr|J3QLV6|J3QLV6_HUMAN 174 H-PdvIHSVCWNSNGSLLATTCKDKTLRIID 203 6.3347*************99*******966 PP >> sp|B1ANS9|WDR64_HUMAN WD repeat-containing protein 64 OS=Homo sapiens GN=WDR64 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.032 2.6 13 37 .. 330 350 .. 316 351 .. 0.75 2 ! 17.7 0.0 0.00029 0.024 6 38 .] 493 528 .. 488 528 .. 0.85 3 ? 7.0 0.0 0.72 58 24 37 .. 784 797 .. 775 798 .. 0.90 4 ? 7.5 0.0 0.5 40 4 37 .. 860 894 .. 857 895 .. 0.69 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.032 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ + +++G+dD+ +r+W sp|B1ANS9|WDR64_HUMAN 330 CYCV----KANVIVTGGDDKVIRLW 350 5566....778899*********** PP == domain 2 score: 17.7 bits; conditional E-value: 0.00029 EEESS.SS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ss..vtslafspdgawlasGsdDgtvriWd 38 +l+ H ++ vts a++ +g ++a+G ++gtvriWd sp|B1ANS9|WDR64_HUMAN 493 ILEPHgFNteVTSAAVDESGFLFATGAYNGTVRIWD 528 5677862258****************99*******9 PP == domain 3 score: 7.0 bits; conditional E-value: 0.72 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 l+++++Dg++r+W sp|B1ANS9|WDR64_HUMAN 784 ILVTAHEDGHLRLW 797 5899********** PP == domain 4 score: 7.5 bits; conditional E-value: 0.5 EEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss..vtslafspdgawlasGsdDgtvriW 37 l ++++H s + + + +++ ++++s Dg+vr+W sp|B1ANS9|WDR64_HUMAN 860 LLSWRAH-SleIIQVIYVEEKQVVLTASIDGSVRLW 894 5666777.33444565555666689*********** PP >> sp|Q9HAD4|WDR41_HUMAN WD repeat-containing protein 41 OS=Homo sapiens GN=WDR41 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.0 0.0084 0.68 4 38 .] 36 70 .. 33 70 .. 0.78 2 ! 15.2 0.0 0.0019 0.15 2 38 .] 75 119 .. 74 119 .. 0.73 3 ! 21.7 0.0 1.6e-05 0.0013 3 37 .. 317 349 .. 315 350 .. 0.88 4 ? 9.1 0.1 0.16 13 3 38 .] 397 432 .. 395 432 .. 0.76 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.0084 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l++H + v+ l +d ++ as++dDg v +W+ sp|Q9HAD4|WDR41_HUMAN 36 LLVLKAHhDIVRFLVQLDDYRF-ASAGDDGIVVVWN 70 6789999444788888888888.67777*******8 PP == domain 2 score: 15.2 bits; conditional E-value: 0.0019 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd sp|Q9HAD4|WDR41_HUMAN 75 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 119 6788999**7779999855555544444444779999*******9 PP == domain 3 score: 21.7 bits; conditional E-value: 1.6e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++t +H s+v ++a p+ +++ s+s+Dg+vriW sp|Q9HAD4|WDR41_HUMAN 317 CQKT--AHdSNVLHVARLPNRQLI-SCSEDGSVRIW 349 6777..9*777************7.7999******* PP == domain 4 score: 9.1 bits; conditional E-value: 0.16 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ l GH ssv + + d+ ++ ++s D+ + +W+ sp|Q9HAD4|WDR41_HUMAN 397 LIGDLIGHsSSVEMFLYFEDHGLV-TCSADHLIILWK 432 567789**7779666566666665.7888*******6 PP >> sp|Q8TBY9|WDR66_HUMAN WD repeat-containing protein 66 OS=Homo sapiens GN=WDR66 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 0.3 1.1e-06 8.6e-05 2 38 .] 290 329 .. 289 329 .. 0.92 2 ? 8.4 0.0 0.25 20 13 38 .] 609 634 .. 597 634 .. 0.91 3 ? 7.2 0.0 0.6 48 12 31 .. 695 714 .. 688 720 .. 0.80 4 ? 11.2 0.2 0.034 2.8 9 38 .] 889 920 .. 881 920 .. 0.84 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 1.1e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEET..TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsd..DgtvriWd 38 +++++l GH + +++l++s d +w+a++++ D+ v iWd sp|Q8TBY9|WDR66_HUMAN 290 NNQYHLQGHaNIISCLCVSEDRRWIATADKgpDCLVIIWD 329 799******7779**************98788*******9 PP == domain 2 score: 8.4 bits; conditional E-value: 0.25 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 +++++ +p+++++a Gs g +++W+ sp|Q8TBY9|WDR66_HUMAN 609 ICAISCHPYQPLIAIGSICGMIKVWN 634 999**********************8 PP == domain 3 score: 7.2 bits; conditional E-value: 0.6 SEEEEEEETTSSEEEEEETT CS WD40 12 svtslafspdgawlasGsdD 31 svt+++fs+d++++a++++ sp|Q8TBY9|WDR66_HUMAN 695 SVTHISFSHDSQYMATADRS 714 6*************987554 PP == domain 4 score: 11.2 bits; conditional E-value: 0.034 SS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawla.sGsdDgtvriWd 38 H ++v ++a+s dg + + +G+ D++v W+ sp|Q8TBY9|WDR66_HUMAN 889 CHpNGVAGMAVSYDGCYAFtAGGHDRSVVQWK 920 79999************6537788*******5 PP >> tr|H0YFG0|H0YFG0_HUMAN Autophagy-related protein 16-2 (Fragment) OS=Homo sapiens GN=ATG16L2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.2 0.0 3e-07 2.4e-05 5 38 .] 168 202 .. 165 202 .. 0.94 2 ? 11.3 0.0 0.032 2.6 5 37 .. 212 245 .. 209 246 .. 0.86 3 ! 16.3 0.0 0.00079 0.064 5 38 .] 254 288 .. 250 288 .. 0.81 Alignments for each domain: == domain 1 score: 27.2 bits; conditional E-value: 3e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l++H s v++++f p++++la+G+ D+ +++W+ tr|H0YFG0|H0YFG0_HUMAN 168 DVLDAHlSEVNAVRFGPNSSLLATGGADRLIHLWN 202 5799**999*************************8 PP == domain 2 score: 11.3 bits; conditional E-value: 0.032 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+G +s+ts++f+p+g ++++++++ +W tr|H0YFG0|H0YFG0_HUMAN 212 QTLEGAgGSITSVDFDPSGYQVLAATYNQAAQLW 245 689999888************9999878888888 PP == domain 3 score: 16.3 bits; conditional E-value: 0.00079 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl+GH++ vt+ +f + ++Gs+D+tv+ Wd tr|H0YFG0|H0YFG0_HUMAN 254 ETLSGHKDkVTAAKFKLTRHQAVTGSRDRTVKEWD 288 589***666****66555555889**********8 PP >> tr|H0YAA3|H0YAA3_HUMAN WD repeat-containing protein 41 (Fragment) OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 0.0069 0.56 4 38 .] 29 63 .. 26 63 .. 0.78 2 ! 15.5 0.0 0.0015 0.12 2 38 .] 68 112 .. 67 112 .. 0.73 3 ! 22.0 0.0 1.3e-05 0.0011 3 37 .. 252 284 .. 250 285 .. 0.88 4 ? 9.3 0.1 0.13 11 3 38 .] 332 367 .. 330 367 .. 0.76 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.0069 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l++H + v+ l +d ++ as++dDg v +W+ tr|H0YAA3|H0YAA3_HUMAN 29 LLVLKAHhDIVRFLVQLDDYRF-ASAGDDGIVVVWN 63 6789999444788888888888.67777*******8 PP == domain 2 score: 15.5 bits; conditional E-value: 0.0015 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd tr|H0YAA3|H0YAA3_HUMAN 68 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 112 6788999**7779999855555544444444779999*******9 PP == domain 3 score: 22.0 bits; conditional E-value: 1.3e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++t +H s+v ++a p+ +++ s+s+Dg+vriW tr|H0YAA3|H0YAA3_HUMAN 252 CQKT--AHdSNVLHVARLPNRQLI-SCSEDGSVRIW 284 6777..9*777************7.7999******* PP == domain 4 score: 9.3 bits; conditional E-value: 0.13 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ l GH ssv + + d+ ++ ++s D+ + +W+ tr|H0YAA3|H0YAA3_HUMAN 332 LIGDLIGHsSSVEMFLYFEDHGLV-TCSADHLIILWK 367 567789**7779666566666665.7888*******6 PP >> tr|H0Y626|H0Y626_HUMAN Uncharacterized protein OS=Homo sapiens PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 0.0015 0.12 6 38 .] 758 791 .. 755 791 .. 0.95 2 ! 25.8 0.6 8e-07 6.4e-05 1 38 [] 795 831 .. 795 831 .. 0.88 3 ? 7.4 0.1 0.52 43 1 37 [. 835 869 .. 835 870 .. 0.89 4 ! 14.5 0.2 0.0031 0.25 2 37 .. 875 909 .. 874 910 .. 0.83 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 0.0015 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH +sv++l + + ++l+sGs+D ++r Wd tr|H0Y626|H0Y626_HUMAN 758 EFRGHaGSVRALFLCEEENFLLSGSYDLSIRYWD 791 599**999*************************9 PP == domain 2 score: 25.8 bits; conditional E-value: 8e-07 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 g c+r++ GH + +t++ ++ l+sG++D+ v++Wd tr|H0Y626|H0Y626_HUMAN 795 GVCTRIFGGHqGTITCM------DLcknrLVSGGRDCQVKVWD 831 579*******777****......66666699***********9 PP == domain 3 score: 7.4 bits; conditional E-value: 0.52 TEEEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssv..tslafspdgawlasGsdDgtvriW 37 g+cl+t++ H +++ t + + ++++s+++ g v++W tr|H0Y626|H0Y626_HUMAN 835 GKCLKTFR-HkDPIlaTRI----NDTYIVSSCERGLVKVW 869 79*****9.9666778999....9*****9999******* PP == domain 4 score: 14.5 bits; conditional E-value: 0.0031 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 q+++tl+GH + v +l f +w l+sGs Dg v+ W tr|H0Y626|H0Y626_HUMAN 875 QLVKTLSGHeGAVKCLFF---DQWhLLSGSTDGLVMAW 909 789******888****54...477557********999 PP >> tr|F5H3E9|F5H3E9_HUMAN Proteasomal ATPase-associated factor 1 (Fragment) OS=Homo sapiens GN=PAAF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.0 0.0 4.5e-09 3.6e-07 2 38 .] 10 47 .. 9 47 .. 0.94 2 ! 24.5 0.2 2.1e-06 0.00017 2 38 .] 52 89 .. 51 89 .. 0.87 Alignments for each domain: == domain 1 score: 33.0 bits; conditional E-value: 4.5e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+l+GH ++v++++f p+g ++sG++D ++iW+ tr|F5H3E9|F5H3E9_HUMAN 10 ELRRVLEGHvFDVNCCRFFPSGLVVLSGGMDAQLKIWS 47 67799****999*************************5 PP == domain 2 score: 24.5 bits; conditional E-value: 2.1e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ t++GH +++ + a + g+ ++s+s+Dgt r+Wd tr|F5H3E9|F5H3E9_HUMAN 52 SCVVTFKGHkGGILDTAIVDRGRNVVSASRDGTARLWD 89 6999*****777977777888888899**********9 PP >> tr|I3L167|I3L167_HUMAN Coronin OS=Homo sapiens GN=CORO7-PAM16 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.2 0.1 1.6e-08 1.3e-06 4 37 .. 70 105 .. 67 106 .. 0.88 2 ? 5.8 0.0 1.7 1.4e+02 16 38 .] 132 154 .. 123 154 .. 0.76 3 ! 15.7 0.0 0.0013 0.1 2 38 .] 159 196 .. 158 196 .. 0.88 Alignments for each domain: == domain 1 score: 31.2 bits; conditional E-value: 1.6e-08 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriW 37 + +l Hs+ vt+l+fsp ++l a+Gs D+tv++W tr|I3L167|I3L167_HUMAN 70 VAHLGCHSDlVTDLDFSPFDDFLlATGSADRTVKLW 105 678999*8889***********7369********** PP == domain 2 score: 5.8 bits; conditional E-value: 1.7 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 l+f+p ++ ++ + tv++Wd tr|I3L167|I3L167_HUMAN 132 LQFHPTSDGILVSAAGTTVKVWD 154 567888888654444*******9 PP == domain 3 score: 15.7 bits; conditional E-value: 0.0013 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 q+l++l +H++ v s +s+dga++ ++++D+ +ri+d tr|I3L167|I3L167_HUMAN 159 QPLTELAAHGDlVQSAVWSRDGALVGTACKDKQLRIFD 196 89999****77899999*******856789******98 PP >> sp|Q9HBG6-5|IF122_HUMAN Isoform 5 of Intraflagellar transport protein 122 homolog OS=Homo sapiens GN=IFT122 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.87 70 10 34 .. 13 45 .. 4 47 .. 0.77 2 ! 28.2 0.0 1.4e-07 1.2e-05 2 37 .. 44 80 .. 43 81 .. 0.91 3 ? 3.7 0.2 8.1 6.5e+02 10 31 .. 143 164 .. 134 171 .. 0.77 4 ? 6.5 0.0 1 81 4 36 .. 174 209 .. 172 211 .. 0.78 5 ? 4.5 0.0 4.3 3.5e+02 9 24 .. 225 241 .. 217 244 .. 0.86 6 ? 10.7 0.1 0.05 4 7 37 .. 368 399 .. 362 400 .. 0.79 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.87 SSSEEEEEEETTSSE..EEEEET.......TSEE CS WD40 10 Hssvtslafspdgaw..lasGsd.......Dgtv 34 H +++++af pdg+ la+Gs+ Dgt+ sp|Q9HBG6-5|IF122_HUMAN 13 H-CINDIAFKPDGTQliLAAGSRllvydtsDGTL 45 6.7************4446898666666667776 PP == domain 2 score: 28.2 bits; conditional E-value: 1.4e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 ++l+ l+GH++ v+++a+ +dg+ +asGs D++v iW sp|Q9HBG6-5|IF122_HUMAN 44 TLLQPLKGHKDtVYCVAYAKDGKRFASGSADKSVIIW 80 67899****555************************* PP == domain 3 score: 3.7 bits; conditional E-value: 8.1 SSS.EEEEEEETTSSEEEEEETT CS WD40 10 Hss.vtslafspdgawlasGsdD 31 H++ + +++++p + las+s sp|Q9HBG6-5|IF122_HUMAN 143 HNDaIQCVSYNPITHQLASCS-S 164 75569***99999999**997.3 PP == domain 4 score: 6.5 bits; conditional E-value: 1 EEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ss..vtslafspdgawlasGsdDgtvri 36 +++ + H ss + ++++ dg++la G+ +g + i sp|Q9HBG6-5|IF122_HUMAN 174 QKSVSKHkSSskIICCSWTNDGQYLALGMFNGIISI 209 56778897447977**********987876777765 PP == domain 5 score: 4.5 bits; conditional E-value: 4.3 SS.SSEEEEEEETTSSE CS WD40 9 GH.ssvtslafspdgaw 24 G s+++s++++p+++w sp|Q9HBG6-5|IF122_HUMAN 225 GSlSPIWSICWNPSSRW 241 56678***********9 PP == domain 6 score: 10.7 bits; conditional E-value: 0.05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ sp|Q9HBG6-5|IF122_HUMAN 368 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 399 444545698888*****************876 PP >> sp|Q6PJI9-2|WDR59_HUMAN Isoform 2 of WD repeat-containing protein 59 OS=Homo sapiens GN=WDR59 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.2 0.0011 0.09 4 38 .] 98 134 .. 95 134 .. 0.85 2 ? 12.8 0.2 0.01 0.82 20 38 .] 159 176 .. 143 176 .. 0.76 3 ! 24.6 0.3 1.9e-06 0.00015 8 38 .] 188 220 .. 182 220 .. 0.89 4 ? 10.1 0.1 0.076 6.1 2 37 .. 273 314 .. 272 315 .. 0.74 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0011 EEEEESSSS.EEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgaw.......lasGsdDgtvriWd 38 +tl GH+ +++l +w l+++s D ++iWd sp|Q6PJI9-2|WDR59_HUMAN 98 GTTLQGHTRvISDL------DWavfepdlLVTSSVDTYIYIWD 134 57899**7767***......8888888888899*********9 PP == domain 2 score: 12.8 bits; conditional E-value: 0.01 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 ++ + la+++ Dg vriWd sp|Q6PJI9-2|WDR59_HUMAN 159 KNANCLATSH-DGDVRIWD 176 3445588888.*******9 PP == domain 3 score: 24.6 bits; conditional E-value: 1.9e-06 ESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGsdDgtvriWd 38 +H s +++l+++pd+ + a++s D++v++Wd sp|Q6PJI9-2|WDR59_HUMAN 188 AAHlSKIHGLDWHPDSEHIlATSSQDNSVKFWD 220 589999************626889********9 PP == domain 4 score: 10.1 bits; conditional E-value: 0.076 EEEEEEESSSS.EEEEE......EETTSSEEEEE.ETTSEEEEE CS WD40 2 qclrtltGHss.vtsla......fspdgawlasG.sdDgtvriW 37 ++++t+ GH++ v ++ s+d +++ s+D+t+r+W sp|Q6PJI9-2|WDR59_HUMAN 273 TPVHTFVGHDDvVLEFQwrkqkeGSKDYQLV--TwSRDQTLRMW 314 589******7756888556666666666665..5588******* PP >> sp|Q92828|COR2A_HUMAN Coronin-2A OS=Homo sapiens GN=CORO2A PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.1 8.2e-06 0.00066 9 38 .] 80 111 .. 70 111 .. 0.91 2 ? 11.2 0.0 0.033 2.7 6 38 .] 127 161 .. 121 161 .. 0.75 3 ! 17.9 0.1 0.00025 0.02 3 38 .] 172 208 .. 170 208 .. 0.89 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 8.2e-06 SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 GH ++v +++++p ++ +as+s+D t++iW+ sp|Q92828|COR2A_HUMAN 80 GHrGNVLDVKWNPFDDFeIASCSEDATIKIWS 111 9*888**************************5 PP == domain 2 score: 11.2 bits; conditional E-value: 0.033 EEESS.SSEEEEE.EETTSSEEE.EEETTSEEEEEE CS WD40 6 tltGH.ssvtsla.fspdgawla.sGsdDgtvriWd 38 +l GH v +l ++p a ++ s+++D +v+iW+ sp|Q92828|COR2A_HUMAN 127 ELVGHaRRV-GLVeWHPTAANILfSAGYDYKVMIWN 161 577884448.444599999996558888*******8 PP == domain 3 score: 17.9 bits; conditional E-value: 0.00025 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ t++ H++ + s++f+ +g++la+ ++D+++r+ d sp|Q92828|COR2A_HUMAN 172 PMSTISCHQDvILSMSFNTNGSLLATTCKDRKIRVID 208 788999**8856*************99*******965 PP >> sp|Q53HC9|TSSC1_HUMAN Protein TSSC1 OS=Homo sapiens GN=TSSC1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.1 3.4 2.8e+02 9 38 .] 133 163 .. 123 163 .. 0.66 2 ! 25.6 0.0 9.5e-07 7.7e-05 9 38 .] 226 257 .. 218 257 .. 0.88 3 ? 10.9 0.1 0.04 3.3 2 34 .. 263 297 .. 262 299 .. 0.76 4 ! 16.2 0.0 0.0009 0.073 4 36 .. 340 374 .. 337 374 .. 0.89 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 3.4 SSSSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GHssvtslafspdgaw..lasGsdDgtvriWd 38 +H++ ++ + p g+ ++ + D+++ +Wd sp|Q53HC9|TSSC1_HUMAN 133 AHGNMACVVWEPMGDGkkII-SLADNHILLWD 163 56445677655555555576.545*******9 PP == domain 2 score: 25.6 bits; conditional E-value: 9.5e-07 SSSS.EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgaw.lasGsdDgtvriWd 38 +H+ v++l+f+p++++ las++dD++v++Wd sp|Q53HC9|TSSC1_HUMAN 226 AHGQlVRDLDFNPNKQYyLASCGDDCKVKFWD 257 784469***********99************9 PP == domain 3 score: 10.9 bits; conditional E-value: 0.04 EEEEEEESSSS.EEEEEEETTSSEEE.EEETTSEE CS WD40 2 qclrtltGHss.vtslafspdgawla.sGsdDgtv 34 ++++tl+ Hs+ v+ ++++++++ l+ +Gs D v sp|Q53HC9|TSSC1_HUMAN 263 EPVKTLEEHSHwVWNVRYNHSHDQLVlTGSSDSRV 297 6899*****666*****6666666544**889877 PP == domain 4 score: 16.2 bits; conditional E-value: 0.0009 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvri 36 + t++ H +sv+++++s+ +wl+++ s+Dg + i sp|Q53HC9|TSSC1_HUMAN 340 IATYEEHeDSVYAVDWSSADPWLFASlSYDGRLVI 374 6899***999*************999999*98865 PP >> sp|Q9NW82|WDR70_HUMAN WD repeat-containing protein 70 OS=Homo sapiens GN=WDR70 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.1 0.00057 0.046 10 38 .] 180 210 .. 168 210 .. 0.86 2 ? 3.4 0.0 9.4 7.6e+02 4 29 .. 224 250 .. 221 260 .. 0.76 3 ! 14.3 0.0 0.0036 0.29 13 38 .] 334 360 .. 323 360 .. 0.86 4 ! 16.4 0.6 0.00076 0.061 7 38 .] 371 406 .. 365 406 .. 0.79 5 ? 6.6 0.0 0.92 75 14 29 .. 427 442 .. 418 452 .. 0.90 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 0.00057 S..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H..ssvtslafspdgawlasGsdDgtvriWd 38 H + v++l +p+ga l++G++D v++Wd sp|Q9NW82|WDR70_HUMAN 180 HgtKTVSALGLDPSGARLVTGGYDYDVKFWD 210 54366999999*******************9 PP == domain 2 score: 3.4 bits; conditional E-value: 9.4 EEEEESSSSEEEEEEETTSSE..EEEEE CS WD40 4 lrtltGHssvtslafspdgaw..lasGs 29 l+ ++ H + sl++s g++ ++sGs sp|Q9NW82|WDR70_HUMAN 224 LQPCECH-QIKSLQYSNTGDMilVVSGS 250 5667899.8************4435887 PP == domain 3 score: 14.3 bits; conditional E-value: 0.0036 E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 v.tslafspdgawlasGsdDgtvriWd 38 + t + +s+dg+++a+++ +g++ iWd sp|Q9NW82|WDR70_HUMAN 334 IpTTCTYSRDGNLIAAACQNGSIQIWD 360 468899********************9 PP == domain 4 score: 16.4 bits; conditional E-value: 0.00076 EE.SS.SS..EEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 7 lt.GH.ss..vtslafspdgawlas.GsdDgtvriWd 38 ++ +H s+ +++ fs dg+ las G+ D ++++Wd sp|Q9NW82|WDR70_HUMAN 371 YKqAHdSGtdTSCVTFSYDGNVLASrGG-DDSLKLWD 406 544775445578***********97689.*******9 PP == domain 5 score: 6.6 bits; conditional E-value: 0.92 EEEEEETTSSEEEEEE CS WD40 14 tslafspdgawlasGs 29 t+++fspd +++++G+ sp|Q9NW82|WDR70_HUMAN 427 TDCCFSPDDKLIVTGT 442 89************94 PP >> sp|Q9UKT8|FBXW2_HUMAN F-box/WD repeat-containing protein 2 OS=Homo sapiens GN=FBXW2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 0.013 1.1 5 38 .] 142 174 .. 140 174 .. 0.78 2 ? 8.9 0.1 0.18 15 1 37 [. 178 211 .. 178 212 .. 0.88 3 ! 25.1 0.1 1.3e-06 0.00011 4 37 .. 219 253 .. 216 253 .. 0.92 4 ! 13.5 0.1 0.0061 0.49 1 37 [. 258 304 .. 258 304 .. 0.78 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH v++l + +dg l++GsdD + ++Wd sp|Q9UKT8|FBXW2_HUMAN 142 SSLIGHsARVYAL-YYKDGL-LCTGSDDLSAKLWD 174 5799**555**99.444444.589**********9 PP == domain 2 score: 8.9 bits; conditional E-value: 0.18 TEEEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHssvtslafspdgawlasGsdDgtvriW 37 gqc++ + +H t+ a+ d + l++Gs D+tv W sp|Q9UKT8|FBXW2_HUMAN 178 GQCVYGIQTH---TCAAVKFDEQKLVTGSFDNTVACW 211 6788888899...89999999999**********999 PP == domain 3 score: 25.1 bits; conditional E-value: 1.3e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++++GH + v s++++++ + l+sGs D tv++W sp|Q9UKT8|FBXW2_HUMAN 219 TQHFRGHtGAVFSVDYNDELDILVSGSADFTVKVW 253 689****777************************* PP == domain 4 score: 13.5 bits; conditional E-value: 0.0061 TEEEEEEESS.SSEEEEE..........EETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtsla..........fspdgawlasGsdDgtvriW 37 g+cl tltGH +vt + sp l+s++ + ++iW sp|Q9UKT8|FBXW2_HUMAN 258 GTCLNTLTGHtEWVTKVVlqkckvksllHSPGDYILLSAD-KYEIKIW 304 68********777887777777777884666666678877.******* PP >> tr|B4DDM6|B4DDM6_HUMAN Mitotic checkpoint protein BUB3 OS=Homo sapiens GN=BUB3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.0 1.3e-06 0.0001 9 38 .] 14 44 .. 8 44 .. 0.91 2 ? 3.7 0.0 8.1 6.6e+02 13 38 .] 60 83 .. 49 83 .. 0.78 3 ! 16.8 0.0 0.00055 0.045 8 38 .] 142 182 .. 135 182 .. 0.78 4 ? 7.6 0.0 0.47 38 10 29 .. 193 215 .. 185 225 .. 0.71 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 1.3e-06 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++++ ++p+ + +++Gs+D+tv++Wd tr|B4DDM6|B4DDM6_HUMAN 14 THdAPIRCVEYCPEVNVMVTGSWDQTVKLWD 44 68777*************************9 PP == domain 2 score: 3.7 bits; conditional E-value: 8.1 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v+ l s +g+ l+ G+ + v +Wd tr|B4DDM6|B4DDM6_HUMAN 60 VYTL--SVSGDRLIVGTAGRRVLVWD 83 6556..668888888*99*******9 PP == domain 3 score: 16.8 bits; conditional E-value: 0.00055 ESS..SS........EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH..ss........vtslafspdgawlasGsdDgtvriWd 38 + H + v++++f+ ++ +a+G+ Dg v iWd tr|B4DDM6|B4DDM6_HUMAN 142 KCHrlKEnnieqiypVNAISFHNIHNTFATGGSDGFVNIWD 182 5555533445666669***************88*******9 PP == domain 4 score: 7.6 bits; conditional E-value: 0.47 S...SSEEEEEEETTSSEEEEEE CS WD40 10 H...ssvtslafspdgawlasGs 29 H +s+ slafs dg+ la +s tr|B4DDM6|B4DDM6_HUMAN 193 HrypTSIASLAFSNDGTTLAIAS 215 55445699**********98443 PP >> tr|D6RD66|D6RD66_HUMAN WD repeat-containing protein 1 (Fragment) OS=Homo sapiens GN=WDR1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.0 0.008 0.65 7 38 .] 58 90 .. 54 90 .. 0.81 2 ! 12.9 0.0 0.0095 0.77 3 32 .. 142 173 .. 140 177 .. 0.82 3 ! 27.6 0.0 2.2e-07 1.8e-05 6 38 .] 188 221 .. 183 221 .. 0.86 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 0.008 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 +t H + v ++ p+g ++asG+ g++riWd tr|D6RD66|D6RD66_HUMAN 58 YTEHAHqVVVAKYAPSGFYIASGDVSGKLRIWD 90 66673346566799******************9 PP == domain 2 score: 12.9 bits; conditional E-value: 0.0095 EEEEEESSSS.EEEEEEETTSSE.EEEEETTS CS WD40 3 clrtltGHss.vtslafspdgaw.lasGsdDg 32 ++++tGH+ ++s++ ++ ++ la+GsdD+ tr|D6RD66|D6RD66_HUMAN 142 SVGEITGHNKvINSVDIKQSRPYrLATGSDDN 173 67889***6647***9999999999****886 PP == domain 3 score: 27.6 bits; conditional E-value: 2.2e-07 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 t+ Hs v++++fspdg+ +a++s Dg ++i+d tr|D6RD66|D6RD66_HUMAN 188 TIGDHSRfVNCVRFSPDGNRFATASADGQIYIYD 221 45579445************************98 PP >> sp|Q96S15-2|WDR24_HUMAN Isoform 2 of WD repeat-containing protein 24 OS=Homo sapiens GN=WDR24 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.023 1.8 7 38 .] 116 149 .. 110 149 .. 0.82 2 ? 6.8 0.0 0.84 68 4 38 .] 156 192 .. 153 192 .. 0.81 3 ! 27.6 0.2 2.3e-07 1.8e-05 2 38 .] 198 236 .. 197 236 .. 0.85 4 ? 9.7 0.1 0.098 8 12 38 .] 253 282 .. 238 282 .. 0.71 5 ? 5.8 0.0 1.8 1.4e+02 7 34 .. 293 323 .. 288 325 .. 0.83 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.023 EESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawla.sGsdDgtvriWd 38 +t H+ v+ ++f+p a ++ sGs Dg + +d sp|Q96S15-2|WDR24_HUMAN 116 FTEHKRtVNKVCFHPTEAHVLlSGSQDGFMKCFD 149 7899556************644******888766 PP == domain 2 score: 6.8 bits; conditional E-value: 0.84 EEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + t++G+ sv++++fs + +as ++g+v +Wd sp|Q96S15-2|WDR24_HUMAN 156 VSTFSGQsESVRDVQFSIRDYFtFASTFENGNVQLWD 192 789****777****777666666777789*******9 PP == domain 3 score: 27.6 bits; conditional E-value: 2.3e-07 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +c r +t+H ++v +++++p+ + la+G++D+ v++Wd sp|Q96S15-2|WDR24_HUMAN 198 RCERMFTAHnGPVFCCDWHPEDRGwLATGGRDKMVKVWD 236 58999****777****966666556*************9 PP == domain 4 score: 9.7 bits; conditional E-value: 0.098 SEEEEEEETTSSE.EEEEET..TSEEEEEE CS WD40 12 svtslafspdgaw.lasGsd..DgtvriWd 38 sv +++ p+ + la++s+ D+++++Wd sp|Q96S15-2|WDR24_HUMAN 253 SVARVKWRPECRHhLATCSMmvDHNIYVWD 282 3555658888888568998556*******9 PP == domain 5 score: 5.8 bits; conditional E-value: 1.8 EESSSSE.EEEE..EETTSSEEEEEETTSEE CS WD40 7 ltGHssv.tsla..fspdgawlasGsdDgtv 34 ++ H +v t++a ++d ++l+sGs+D ++ sp|Q96S15-2|WDR24_HUMAN 293 FEEHRDVtTGIAwrHPHDPSFLLSGSKDSSL 323 667877988998888999999*******987 PP >> tr|H7C3Y7|H7C3Y7_HUMAN Neurobeachin-like protein 2 (Fragment) OS=Homo sapiens GN=NBEAL2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.013 1 13 36 .. 799 825 .. 784 825 .. 0.74 2 ! 24.4 0.3 2.2e-06 0.00018 1 37 [. 831 868 .. 831 869 .. 0.90 3 ! 19.0 0.0 0.00012 0.0095 2 36 .. 883 918 .. 882 919 .. 0.92 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 E..EEEEEETTSSEEEEE.ETTSEEEE CS WD40 13 v..tslafspdgawlasG.sdDgtvri 36 v +la+ pdg++l+sG ++Dg++r+ tr|H7C3Y7|H7C3Y7_HUMAN 799 VsgQALAVAPDGKLLFSGgHWDGSLRV 825 6333566**********9569****97 PP == domain 2 score: 24.4 bits; conditional E-value: 2.2e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l l+ H + vt+la + g +l+sGs+D t+++W tr|H7C3Y7|H7C3Y7_HUMAN 831 GKLLSQLSCHlDVVTCLALDTCGIYLISGSRDTTCMVW 868 5788899***5558************************ PP == domain 3 score: 19.0 bits; conditional E-value: 0.00012 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++++l GH v+++a s + ++ +sGs+Dgtv i tr|H7C3Y7|H7C3Y7_HUMAN 883 KPVQVLYGHgAAVSCVAISTELDMAVSGSEDGTVII 918 68999****766*********************976 PP >> sp|Q969X6-3|CIR1A_HUMAN Isoform 3 of Cirhin OS=Homo sapiens GN=CIRH1A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.042 3.4 11 38 .] 17 44 .. 1 44 [. 0.80 2 ! 13.3 0.0 0.0072 0.58 12 37 .. 103 128 .. 95 129 .. 0.89 3 ? 9.7 0.0 0.1 8.1 11 31 .. 146 166 .. 136 169 .. 0.81 4 ? 3.5 0.4 8.8 7.2e+02 7 34 .. 283 309 .. 277 311 .. 0.70 5 ? 10.6 0.0 0.05 4.1 5 29 .. 475 503 .. 471 512 .. 0.65 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.042 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 s+++++a++ ++ la + Dgtv i++ sp|Q969X6-3|CIR1A_HUMAN 17 SGIRCVAYNNQSNRLAVSRTDGTVEIYN 44 349************99967******97 PP == domain 2 score: 13.3 bits; conditional E-value: 0.0072 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +++s+a sp+g+ l+ G++Dg+v+++ sp|Q969X6-3|CIR1A_HUMAN 103 PIWSMAASPSGSQLLVGCEDGSVKLF 128 59**********************97 PP == domain 3 score: 9.7 bits; conditional E-value: 0.1 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 s + sl+++p+g+ +a+Gs D sp|Q969X6-3|CIR1A_HUMAN 146 SRILSLSWHPSGTHIAAGSID 166 3499**************966 PP == domain 4 score: 3.5 bits; conditional E-value: 8.8 EESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtv 34 + H +v+ +a sp sG+ D ++ sp|Q969X6-3|CIR1A_HUMAN 283 FQHHtHDVRTVAHSPTALI--SGGTDTHL 309 5555336*99988777655..89889987 PP == domain 5 score: 10.6 bits; conditional E-value: 0.05 EEEESSSS.EEEEE...EETTSSEEEEEE CS WD40 5 rtltGHss.vtsla...fspdgawlasGs 29 + + +s+ v +++ +spdg+wla+++ sp|Q969X6-3|CIR1A_HUMAN 475 HAFQPQSGtVEAMCllaVSPDGNWLAASG 503 55544422477777778********9665 PP >> sp|Q969X6-2|CIR1A_HUMAN Isoform 2 of Cirhin OS=Homo sapiens GN=CIRH1A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.038 3.1 11 38 .] 17 44 .. 1 44 [. 0.80 2 ! 13.5 0.0 0.0065 0.52 12 37 .. 103 128 .. 95 129 .. 0.89 3 ? 9.8 0.0 0.09 7.3 11 31 .. 146 166 .. 136 169 .. 0.81 4 ? 3.7 0.4 7.9 6.4e+02 7 34 .. 283 309 .. 277 311 .. 0.70 5 ? 9.7 0.1 0.1 8.1 13 29 .. 369 388 .. 353 397 .. 0.72 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.038 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 s+++++a++ ++ la + Dgtv i++ sp|Q969X6-2|CIR1A_HUMAN 17 SGIRCVAYNNQSNRLAVSRTDGTVEIYN 44 349************99967******97 PP == domain 2 score: 13.5 bits; conditional E-value: 0.0065 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +++s+a sp+g+ l+ G++Dg+v+++ sp|Q969X6-2|CIR1A_HUMAN 103 PIWSMAASPSGSQLLVGCEDGSVKLF 128 59**********************97 PP == domain 3 score: 9.8 bits; conditional E-value: 0.09 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 s + sl+++p+g+ +a+Gs D sp|Q969X6-2|CIR1A_HUMAN 146 SRILSLSWHPSGTHIAAGSID 166 3499**************966 PP == domain 4 score: 3.7 bits; conditional E-value: 7.9 EESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtv 34 + H +v+ +a sp sG+ D ++ sp|Q969X6-2|CIR1A_HUMAN 283 FQHHtHDVRTVAHSPTALI--SGGTDTHL 309 5555336*99988777655..89889987 PP == domain 5 score: 9.7 bits; conditional E-value: 0.1 EEEEE...EETTSSEEEEEE CS WD40 13 vtsla...fspdgawlasGs 29 v +++ +spdg+wla+++ sp|Q969X6-2|CIR1A_HUMAN 369 VEAMCllaVSPDGNWLAASG 388 555555569*******9665 PP >> tr|H3BSH7|H3BSH7_HUMAN Cirhin (Fragment) OS=Homo sapiens GN=CIRH1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.059 4.8 11 38 .] 31 58 .. 22 58 .. 0.84 2 ! 13.1 0.0 0.0082 0.67 12 37 .. 117 142 .. 109 143 .. 0.89 3 ? 9.5 0.0 0.11 9.3 11 31 .. 160 180 .. 150 183 .. 0.81 4 ? 10.5 0.0 0.057 4.7 5 29 .. 489 517 .. 485 526 .. 0.65 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.059 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 +++++a++ ++ la + Dgtv i++ tr|H3BSH7|H3BSH7_HUMAN 31 AGIRCVAYNNQSNRLAVSRTDGTVEIYN 58 45*************99967******97 PP == domain 2 score: 13.1 bits; conditional E-value: 0.0082 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +++s+a sp+g+ l+ G++Dg+v+++ tr|H3BSH7|H3BSH7_HUMAN 117 PIWSMAASPSGSQLLVGCEDGSVKLF 142 59**********************97 PP == domain 3 score: 9.5 bits; conditional E-value: 0.11 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 s + sl+++p+g+ +a+Gs D tr|H3BSH7|H3BSH7_HUMAN 160 SRILSLSWHPSGTHIAAGSID 180 3499**************966 PP == domain 4 score: 10.5 bits; conditional E-value: 0.057 EEEESSSS.EEEEE...EETTSSEEEEEE CS WD40 5 rtltGHss.vtsla...fspdgawlasGs 29 + + +s+ v +++ +spdg+wla+++ tr|H3BSH7|H3BSH7_HUMAN 489 HAFQPQSGtVEAMCllaVSPDGNWLAASG 517 55544422477777778********9665 PP >> tr|E7EQF4|E7EQF4_HUMAN Intraflagellar transport protein 122 homolog OS=Homo sapiens GN=IFT122 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.82 67 10 34 .. 13 45 .. 4 47 .. 0.77 2 ! 28.3 0.0 1.4e-07 1.1e-05 2 37 .. 44 80 .. 43 81 .. 0.91 3 ? 3.7 0.2 7.7 6.2e+02 10 31 .. 143 164 .. 134 171 .. 0.77 4 ? 6.6 0.0 0.95 77 4 36 .. 174 209 .. 172 211 .. 0.78 5 ? 10.7 0.1 0.047 3.8 7 37 .. 309 340 .. 303 341 .. 0.79 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.82 SSSEEEEEEETTSSE..EEEEET.......TSEE CS WD40 10 Hssvtslafspdgaw..lasGsd.......Dgtv 34 H +++++af pdg+ la+Gs+ Dgt+ tr|E7EQF4|E7EQF4_HUMAN 13 H-CINDIAFKPDGTQliLAAGSRllvydtsDGTL 45 6.7************4446898666666667776 PP == domain 2 score: 28.3 bits; conditional E-value: 1.4e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 ++l+ l+GH++ v+++a+ +dg+ +asGs D++v iW tr|E7EQF4|E7EQF4_HUMAN 44 TLLQPLKGHKDtVYCVAYAKDGKRFASGSADKSVIIW 80 67899****555************************* PP == domain 3 score: 3.7 bits; conditional E-value: 7.7 SSS.EEEEEEETTSSEEEEEETT CS WD40 10 Hss.vtslafspdgawlasGsdD 31 H++ + +++++p + las+s tr|E7EQF4|E7EQF4_HUMAN 143 HNDaIQCVSYNPITHQLASCS-S 164 75569***99999999**997.3 PP == domain 4 score: 6.6 bits; conditional E-value: 0.95 EEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGH.ss..vtslafspdgawlasGsdDgtvri 36 +++ + H ss + ++++ dg++la G+ +g + i tr|E7EQF4|E7EQF4_HUMAN 174 QKSVSKHkSSskIICCSWTNDGQYLALGMFNGIISI 209 56778897447977**********987876777765 PP == domain 5 score: 10.7 bits; conditional E-value: 0.047 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ tr|E7EQF4|E7EQF4_HUMAN 309 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 340 444545698888*****************876 PP >> sp|Q5XUX1-3|FBXW9_HUMAN Isoform 3 of F-box/WD repeat-containing protein 9 OS=Homo sapiens GN=FBXW9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.1 0.0026 0.21 6 38 .] 170 201 .. 165 201 .. 0.87 2 ! 15.9 2.0 0.0011 0.086 8 38 .] 223 252 .. 213 252 .. 0.79 3 ? 6.1 0.0 1.3 1.1e+02 6 38 .] 262 292 .. 257 292 .. 0.70 4 ? 4.9 0.0 3.2 2.6e+02 20 36 .. 315 331 .. 300 333 .. 0.78 5 ? 12.0 0.1 0.018 1.5 2 36 .. 379 413 .. 378 414 .. 0.75 6 ? 6.2 0.0 1.3 1e+02 10 37 .. 428 454 .. 420 455 .. 0.81 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 0.0026 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH sv s+ + g++ +sGs+D++v +Wd sp|Q5XUX1-3|FBXW9_HUMAN 170 E--GHvASVDSVLLLQGGSLCLSGSRDRNVNLWD 201 4..9*88888888999999999***********9 PP == domain 2 score: 15.9 bits; conditional E-value: 0.0011 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++H ++v+sl + ++sGs+D tv++Wd sp|Q5XUX1-3|FBXW9_HUMAN 223 STHeGWVWSL--AAQDHRVCSGSWDSTVKLWD 252 5898889999..55555588***********9 PP == domain 3 score: 6.1 bits; conditional E-value: 1.3 EEESSSSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGHssvtslafspdgaw....lasGsdDgtvriWd 38 ++++ s v +l ++ l++G++D++v i+d sp|Q5XUX1-3|FBXW9_HUMAN 262 EIKASSAVLCL------SYlpdiLVTGTYDKKVTIYD 292 55555568999......44444479**99*****998 PP == domain 4 score: 4.9 bits; conditional E-value: 3.2 TTSSEEEEEETTSEEEE CS WD40 20 pdgawlasGsdDgtvri 36 d + ++sGs+D+t+ + sp|Q5XUX1-3|FBXW9_HUMAN 315 ADDRHIISGSEDHTLVV 331 6778899*******987 PP == domain 5 score: 12.0 bits; conditional E-value: 0.018 EEEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtlt.GH.ssvtslafspdgawlasGsdDgtvri 36 q++r+++ GH +++t++++s + + s D+t+r+ sp|Q5XUX1-3|FBXW9_HUMAN 379 QLIRSFDvGHsFPITGIQYSVGALY--TTSTDKTIRV 413 78899977**777****66666666..4455*****8 PP == domain 6 score: 6.2 bits; conditional E-value: 1.3 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ++ + + + +g+++++Gs D ++ +W sp|Q5XUX1-3|FBXW9_HUMAN 428 HdNGLNRV--CAEGNLVVAGSGDLSLEVW 454 76666666..779*******88******* PP >> tr|A8MUM1|A8MUM1_HUMAN Protein TSSC1 OS=Homo sapiens GN=TSSC1 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.1 3.8 3e+02 9 38 .] 160 190 .. 150 190 .. 0.66 2 ! 25.5 0.0 1e-06 8.4e-05 9 38 .] 253 284 .. 245 284 .. 0.88 3 ? 10.8 0.1 0.044 3.6 2 34 .. 290 324 .. 289 326 .. 0.76 4 ! 16.0 0.0 0.00098 0.08 4 36 .. 367 401 .. 364 401 .. 0.89 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 3.8 SSSSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 9 GHssvtslafspdgaw..lasGsdDgtvriWd 38 +H++ ++ + p g+ ++ + D+++ +Wd tr|A8MUM1|A8MUM1_HUMAN 160 AHGNMACVVWEPMGDGkkII-SLADNHILLWD 190 56445677655555555576.545*******9 PP == domain 2 score: 25.5 bits; conditional E-value: 1e-06 SSSS.EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgaw.lasGsdDgtvriWd 38 +H+ v++l+f+p++++ las++dD++v++Wd tr|A8MUM1|A8MUM1_HUMAN 253 AHGQlVRDLDFNPNKQYyLASCGDDCKVKFWD 284 784469***********99************9 PP == domain 3 score: 10.8 bits; conditional E-value: 0.044 EEEEEEESSSS.EEEEEEETTSSEEE.EEETTSEE CS WD40 2 qclrtltGHss.vtslafspdgawla.sGsdDgtv 34 ++++tl+ Hs+ v+ ++++++++ l+ +Gs D v tr|A8MUM1|A8MUM1_HUMAN 290 EPVKTLEEHSHwVWNVRYNHSHDQLVlTGSSDSRV 324 6899*****666*****6666666544**889877 PP == domain 4 score: 16.0 bits; conditional E-value: 0.00098 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvri 36 + t++ H +sv+++++s+ +wl+++ s+Dg + i tr|A8MUM1|A8MUM1_HUMAN 367 IATYEEHeDSVYAVDWSSADPWLFASlSYDGRLVI 401 6899***999*************999999*98865 PP >> tr|H7C0R2|H7C0R2_HUMAN Angio-associated migratory cell protein (Fragment) OS=Homo sapiens GN=AAMP PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 0.00013 0.011 7 36 .. 11 41 .. 2 42 .. 0.86 2 ! 17.1 0.1 0.00045 0.037 3 38 .] 105 141 .. 103 141 .. 0.85 3 ! 15.5 0.0 0.0015 0.12 2 37 .. 146 182 .. 145 183 .. 0.85 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 0.00013 EESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvri 36 +GH ++ t++a ++dg+++++Gs D+ ++ tr|H7C0R2|H7C0R2_HUMAN 11 TEGHqGPLTCVAANQDGSLILTGSVDCQAKL 41 46**888*******************98775 PP == domain 2 score: 17.1 bits; conditional E-value: 0.00045 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +lr+ H s++ l + a + ++s Dg vr+Wd tr|H7C0R2|H7C0R2_HUMAN 105 TLRHQCQHqSGIVQLLWEAGTAVVYTCSLDGIVRLWD 141 56666679788999*99999999*************9 PP == domain 3 score: 15.5 bits; conditional E-value: 0.0015 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l+ ++GH + ++a s+d +++++ s D++ +++ tr|H7C0R2|H7C0R2_HUMAN 146 RLLTDYRGHtAEILDFALSKDASLVVTTSGDHKAKVF 182 67889****777************997655**99985 PP >> sp|Q5XUX1-2|FBXW9_HUMAN Isoform 2 of F-box/WD repeat-containing protein 9 OS=Homo sapiens GN=FBXW9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.1 0.0028 0.22 6 38 .] 160 191 .. 155 191 .. 0.87 2 ! 15.9 2.0 0.0011 0.09 8 38 .] 213 242 .. 203 242 .. 0.79 3 ? 6.0 0.0 1.4 1.2e+02 6 38 .] 252 282 .. 247 282 .. 0.70 4 ? 4.9 0.0 3.2 2.6e+02 19 36 .. 334 351 .. 319 353 .. 0.78 5 ? 11.9 0.1 0.02 1.6 2 36 .. 399 433 .. 398 434 .. 0.75 6 ? 6.1 0.0 1.3 1.1e+02 10 37 .. 448 474 .. 440 475 .. 0.81 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.0028 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH sv s+ + g++ +sGs+D++v +Wd sp|Q5XUX1-2|FBXW9_HUMAN 160 E--GHvASVDSVLLLQGGSLCLSGSRDRNVNLWD 191 4..9*88888888999999999***********9 PP == domain 2 score: 15.9 bits; conditional E-value: 0.0011 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++H ++v+sl + ++sGs+D tv++Wd sp|Q5XUX1-2|FBXW9_HUMAN 213 STHeGWVWSL--AAQDHRVCSGSWDSTVKLWD 242 5898889999..55555588***********9 PP == domain 3 score: 6.0 bits; conditional E-value: 1.4 EEESSSSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGHssvtslafspdgaw....lasGsdDgtvriWd 38 ++++ s v +l ++ l++G++D++v i+d sp|Q5XUX1-2|FBXW9_HUMAN 252 EIKASSAVLCL------SYlpdiLVTGTYDKKVTIYD 282 55555568999......44444479**99*****998 PP == domain 4 score: 4.9 bits; conditional E-value: 3.2 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 d + ++sGs+D+t+ + sp|Q5XUX1-2|FBXW9_HUMAN 334 LADDRHIISGSEDHTLVV 351 56778899*******987 PP == domain 5 score: 11.9 bits; conditional E-value: 0.02 EEEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtlt.GH.ssvtslafspdgawlasGsdDgtvri 36 q++r+++ GH +++t++++s + + s D+t+r+ sp|Q5XUX1-2|FBXW9_HUMAN 399 QLIRSFDvGHsFPITGIQYSVGALY--TTSTDKTIRV 433 78899977**777****66666666..4455*****8 PP == domain 6 score: 6.1 bits; conditional E-value: 1.3 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ++ + + + +g+++++Gs D ++ +W sp|Q5XUX1-2|FBXW9_HUMAN 448 HdNGLNRV--CAEGNLVVAGSGDLSLEVW 474 76666666..779*******88******* PP >> sp|Q86W42-3|THOC6_HUMAN Isoform 3 of THO complex subunit 6 homolog OS=Homo sapiens GN=THOC6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.74 60 13 36 .. 27 50 .. 17 52 .. 0.82 2 ? 11.0 0.0 0.039 3.2 2 37 .. 67 100 .. 66 100 .. 0.86 3 ! 25.8 0.0 7.9e-07 6.4e-05 3 38 .] 160 196 .. 158 196 .. 0.84 4 ? 5.9 0.3 1.6 1.3e+02 10 37 .. 218 244 .. 206 245 .. 0.79 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.74 EEEEEEETTSSEEEEEETTSEEEE CS WD40 13 vtslafspdgawlasGsdDgtvri 36 + s+++sp g++la+G g + i sp|Q86W42-3|THOC6_HUMAN 27 IFSQSVSPCGKFLAAGNNYGQIAI 50 88999*********9977887766 PP == domain 2 score: 11.0 bits; conditional E-value: 0.039 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++ t+ +H ++v+s+ +s d ++l s++ Dg v+ W sp|Q86W42-3|THOC6_HUMAN 67 KPVVTFQAHdGPVYSM-VSTDRHLL-SAG-DGEVKAW 100 68899****888****.88888887.689.****988 PP == domain 3 score: 25.8 bits; conditional E-value: 7.9e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r+l+GH + +++la ++ ++sG++Dg vr+Wd sp|Q86W42-3|THOC6_HUMAN 160 FTRVLRGHtDYIHCLALRERSPEVLSGGEDGAVRLWD 196 5799****555****7666666699***********9 PP == domain 4 score: 5.9 bits; conditional E-value: 1.6 SSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriW 37 H++ + +l d++w+++G+ + + +W sp|Q86W42-3|THOC6_HUMAN 218 HNGrwIGCL--ATDSDWMVCGG-GPALTLW 244 644569999..88******999.8877777 PP >> sp|Q96KV7-10|WDR90_HUMAN Isoform 2 of WD repeat-containing protein 90 OS=Homo sapiens GN=WDR90 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.0 1.8e-05 0.0015 2 37 .. 15 61 .. 14 61 .. 0.84 2 ? 8.0 0.0 0.35 28 18 37 .. 90 109 .. 73 110 .. 0.71 3 ! 13.3 0.0 0.0071 0.57 10 34 .. 121 148 .. 114 150 .. 0.80 4 ? 9.6 0.2 0.11 8.9 3 37 .. 158 203 .. 156 203 .. 0.78 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 1.8e-05 EEEEEEE....SS.SS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtlt....GH.ss......vtslafspdgawlasGsdDgtvriW 37 +clr +t H ++ v+ + fsp + a++s+Dg+vr+W sp|Q96KV7-10|WDR90_HUMAN 15 KCLRPFTlprgQHpQPsygfpqVNEVVFSPGESHCATCSEDGSVRVW 61 6888886666556655778899************************* PP == domain 2 score: 8.0 bits; conditional E-value: 0.35 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 p+++ la+G Dg++ri+ sp|Q96KV7-10|WDR90_HUMAN 90 GRPEQQRLAAGYGDGSLRIF 109 5677777****55******7 PP == domain 3 score: 13.3 bits; conditional E-value: 0.0071 S.SSE..EEEEEETTSSEEEEEETTSEE CS WD40 10 H.ssv..tslafspdgawlasGsdDgtv 34 H +v t +afs dg+ ++sG++Dg v sp|Q96KV7-10|WDR90_HUMAN 121 HpHPValTTVAFSTDGQTVLSGDKDGLV 148 5335444******************976 PP == domain 4 score: 9.6 bits; conditional E-value: 0.11 EEEEEESS..SSEEEEE..........EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH..ssvtsla..........fspdgawlasGsdDgtvriW 37 + r+l+ H +++ ++ + wla+++ D+ v +W sp|Q96KV7-10|WDR90_HUMAN 158 TFRVLSDHqgAPISTICvtckecedlgVEGTDLWLAASG-DQRVSVW 203 567888896444766666688888888888999***999.******* PP >> sp|Q9BRP4-3|PAAF1_HUMAN Isoform 3 of Proteasomal ATPase-associated factor 1 OS=Homo sapiens GN=PAAF1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.5 0.0 2.7e-08 2.2e-06 2 38 .] 10 47 .. 9 47 .. 0.94 2 ! 22.0 0.2 1.3e-05 0.0011 2 38 .] 52 89 .. 51 89 .. 0.87 Alignments for each domain: == domain 1 score: 30.5 bits; conditional E-value: 2.7e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+l+GH ++v++++f p+g ++sG++D ++iW+ sp|Q9BRP4-3|PAAF1_HUMAN 10 ELRRVLEGHvFDVNCCRFFPSGLVVLSGGMDAQLKIWS 47 67799****999*************************5 PP == domain 2 score: 22.0 bits; conditional E-value: 1.3e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ t++GH +++ + a + g+ ++s+s+Dgt r+Wd sp|Q9BRP4-3|PAAF1_HUMAN 52 SCVVTFKGHkGGILDTAIVDRGRNVVSASRDGTARLWD 89 6999*****777977777888888899**********9 PP >> sp|Q5XUX1|FBXW9_HUMAN F-box/WD repeat-containing protein 9 OS=Homo sapiens GN=FBXW9 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.1 0.0028 0.23 6 38 .] 170 201 .. 165 201 .. 0.87 2 ! 15.8 2.0 0.0011 0.093 8 38 .] 223 252 .. 213 252 .. 0.79 3 ? 6.0 0.0 1.5 1.2e+02 6 38 .] 262 292 .. 257 292 .. 0.70 4 ? 4.9 0.0 3.3 2.7e+02 19 36 .. 344 361 .. 329 363 .. 0.78 5 ? 11.9 0.1 0.02 1.6 2 36 .. 409 443 .. 408 444 .. 0.75 6 ? 6.1 0.0 1.4 1.1e+02 10 37 .. 458 484 .. 450 485 .. 0.81 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.0028 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH sv s+ + g++ +sGs+D++v +Wd sp|Q5XUX1|FBXW9_HUMAN 170 E--GHvASVDSVLLLQGGSLCLSGSRDRNVNLWD 201 4..9*88888888999999999***********9 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0011 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++H ++v+sl + ++sGs+D tv++Wd sp|Q5XUX1|FBXW9_HUMAN 223 STHeGWVWSL--AAQDHRVCSGSWDSTVKLWD 252 5898889999..55555588***********9 PP == domain 3 score: 6.0 bits; conditional E-value: 1.5 EEESSSSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGHssvtslafspdgaw....lasGsdDgtvriWd 38 ++++ s v +l ++ l++G++D++v i+d sp|Q5XUX1|FBXW9_HUMAN 262 EIKASSAVLCL------SYlpdiLVTGTYDKKVTIYD 292 55555568999......44444479**99*****998 PP == domain 4 score: 4.9 bits; conditional E-value: 3.3 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 d + ++sGs+D+t+ + sp|Q5XUX1|FBXW9_HUMAN 344 LADDRHIISGSEDHTLVV 361 56778899*******987 PP == domain 5 score: 11.9 bits; conditional E-value: 0.02 EEEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtlt.GH.ssvtslafspdgawlasGsdDgtvri 36 q++r+++ GH +++t++++s + + s D+t+r+ sp|Q5XUX1|FBXW9_HUMAN 409 QLIRSFDvGHsFPITGIQYSVGALY--TTSTDKTIRV 443 78899977**777****66666666..4455*****8 PP == domain 6 score: 6.1 bits; conditional E-value: 1.4 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ++ + + + +g+++++Gs D ++ +W sp|Q5XUX1|FBXW9_HUMAN 458 HdNGLNRV--CAEGNLVVAGSGDLSLEVW 484 76666666..779*******88******* PP >> sp|Q86W42|THOC6_HUMAN THO complex subunit 6 homolog OS=Homo sapiens GN=THOC6 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.89 72 13 36 .. 27 50 .. 17 52 .. 0.82 2 ? 10.7 0.0 0.048 3.9 2 37 .. 67 100 .. 66 100 .. 0.86 3 ! 25.6 0.0 9.7e-07 7.9e-05 3 38 .] 160 196 .. 158 196 .. 0.84 4 ? 5.6 0.3 1.9 1.6e+02 10 37 .. 218 244 .. 207 245 .. 0.79 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.89 EEEEEEETTSSEEEEEETTSEEEE CS WD40 13 vtslafspdgawlasGsdDgtvri 36 + s+++sp g++la+G g + i sp|Q86W42|THOC6_HUMAN 27 IFSQSVSPCGKFLAAGNNYGQIAI 50 88999*********9977877766 PP == domain 2 score: 10.7 bits; conditional E-value: 0.048 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++ t+ +H ++v+s+ +s d ++l s++ Dg v+ W sp|Q86W42|THOC6_HUMAN 67 KPVVTFQAHdGPVYSM-VSTDRHLL-SAG-DGEVKAW 100 68899****888****.88888887.689.****988 PP == domain 3 score: 25.6 bits; conditional E-value: 9.7e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r+l+GH + +++la ++ ++sG++Dg vr+Wd sp|Q86W42|THOC6_HUMAN 160 FTRVLRGHtDYIHCLALRERSPEVLSGGEDGAVRLWD 196 5799****555****7666666699***********9 PP == domain 4 score: 5.6 bits; conditional E-value: 1.9 SSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriW 37 H++ + +l d++w+++G+ + + +W sp|Q86W42|THOC6_HUMAN 218 HNGrwIGCL--ATDSDWMVCGG-GPALTLW 244 644569999..88******999.8877777 PP >> tr|H3BM50|H3BM50_HUMAN Target of rapamycin complex subunit LST8 OS=Homo sapiens GN=MLST8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.02 1.6 24 37 .. 14 27 .. 7 28 .. 0.82 2 ! 16.1 0.0 0.00096 0.078 3 38 .] 34 69 .. 32 69 .. 0.86 3 ! 25.7 0.1 9e-07 7.3e-05 5 38 .] 79 113 .. 75 113 .. 0.83 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.02 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W tr|H3BM50|H3BM50_HUMAN 14 ILATAGYDHTVRFW 27 5888888******* PP == domain 2 score: 16.1 bits; conditional E-value: 0.00096 EEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 c+rt H s v++l + pd +++a+++ +++r++d tr|H3BM50|H3BM50_HUMAN 34 CTRTVQ-HqdSQVNALEVTPDRSMIAAAG-YQHIRMYD 69 788875.75444**************99*.******98 PP == domain 3 score: 25.7 bits; conditional E-value: 9e-07 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd tr|H3BM50|H3BM50_HUMAN 79 ISYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 113 55655545688999********************9 PP >> sp|Q92636|FAN_HUMAN Protein FAN OS=Homo sapiens GN=NSMAF PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.04 3.2 6 37 .. 625 657 .. 619 658 .. 0.86 2 ! 16.2 1.9 0.00088 0.071 4 38 .] 707 740 .. 704 740 .. 0.86 3 ? 10.1 0.1 0.075 6.1 10 38 .] 762 791 .. 749 791 .. 0.78 4 ! 13.5 0.5 0.0065 0.52 3 36 .. 797 831 .. 795 833 .. 0.80 5 ? 3.6 0.2 8.4 6.8e+02 20 38 .] 854 872 .. 840 872 .. 0.84 6 ? 12.7 0.1 0.011 0.92 8 38 .] 883 914 .. 877 914 .. 0.78 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.04 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++ H vt++ +s++g+ +++ s D t++++ sp|Q92636|FAN_HUMAN 625 HYKIHkEAVTGITVSRNGSSVFTTSQDSTLKMF 657 68889555**********************986 PP == domain 2 score: 16.2 bits; conditional E-value: 0.00088 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + tl GH + v+ ++++++ + s+s+D tv++W+ sp|Q92636|FAN_HUMAN 707 QDTLMGHdDAVSKICWHDNRLY--SASWDSTVKVWS 740 66888**666****99999999..8**********5 PP == domain 3 score: 10.1 bits; conditional E-value: 0.075 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H sv ++ + +++l+sG++ gtv iWd sp|Q92636|FAN_HUMAN 762 HdVSVDTISLNAASTLLVSGTKEGTVNIWD 791 6444666668888999*************9 PP == domain 4 score: 13.5 bits; conditional E-value: 0.0065 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvri 36 +++ + Hs+ v++ afspd++ ++s + Dg + + sp|Q92636|FAN_HUMAN 797 LMHQIPCHSGiVCDTAFSPDSRHVLSTGTDGCLNV 831 5677889*7757***********986555**9977 PP == domain 5 score: 3.6 bits; conditional E-value: 8.4 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 dg+ ++sGs g + +Wd sp|Q92636|FAN_HUMAN 854 WDGNSVLSGSQSGELLVWD 872 4777788***********9 PP == domain 6 score: 12.7 bits; conditional E-value: 0.011 ESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 GH + vt++ w +++G++D+ + +W+ sp|Q92636|FAN_HUMAN 883 QGHtGAVTCI-------WmneqcssIITGGEDRQIIFWK 914 69*777****.......44444445899**********6 PP >> sp|Q969X6|CIR1A_HUMAN Cirhin OS=Homo sapiens GN=CIRH1A PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 0.048 3.9 11 38 .] 17 44 .. 1 44 [. 0.80 2 ! 13.2 0.0 0.0081 0.65 12 37 .. 103 128 .. 95 129 .. 0.89 3 ? 9.5 0.0 0.11 9 11 31 .. 146 166 .. 136 169 .. 0.81 4 ? 3.4 0.4 9.9 8e+02 7 34 .. 283 309 .. 277 311 .. 0.70 5 ? 10.5 0.0 0.056 4.5 5 29 .. 475 503 .. 471 512 .. 0.65 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.048 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 s+++++a++ ++ la + Dgtv i++ sp|Q969X6|CIR1A_HUMAN 17 SGIRCVAYNNQSNRLAVSRTDGTVEIYN 44 349************99967******97 PP == domain 2 score: 13.2 bits; conditional E-value: 0.0081 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +++s+a sp+g+ l+ G++Dg+v+++ sp|Q969X6|CIR1A_HUMAN 103 PIWSMAASPSGSQLLVGCEDGSVKLF 128 59**********************97 PP == domain 3 score: 9.5 bits; conditional E-value: 0.11 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 s + sl+++p+g+ +a+Gs D sp|Q969X6|CIR1A_HUMAN 146 SRILSLSWHPSGTHIAAGSID 166 3499**************966 PP == domain 4 score: 3.4 bits; conditional E-value: 9.9 EESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtv 34 + H +v+ +a sp sG+ D ++ sp|Q969X6|CIR1A_HUMAN 283 FQHHtHDVRTVAHSPTALI--SGGTDTHL 309 5555336*99988777655..89889987 PP == domain 5 score: 10.5 bits; conditional E-value: 0.056 EEEESSSS.EEEEE...EETTSSEEEEEE CS WD40 5 rtltGHss.vtsla...fspdgawlasGs 29 + + +s+ v +++ +spdg+wla+++ sp|Q969X6|CIR1A_HUMAN 475 HAFQPQSGtVEAMCllaVSPDGNWLAASG 503 55544422477777778********9665 PP >> tr|C9JWF1|C9JWF1_HUMAN WD repeat-containing protein 31 (Fragment) OS=Homo sapiens GN=WDR31 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.0 1.3e-05 0.0011 2 38 .] 26 63 .. 25 63 .. 0.78 2 ! 30.0 0.0 3.7e-08 3e-06 3 38 .] 70 106 .. 68 106 .. 0.89 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.3e-05 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + ++ ++GH + +t +a p ++ ++s+s+D+ v++Wd tr|C9JWF1|C9JWF1_HUMAN 26 NVVKRFKGHEHeITKVACIPKSSQFFSASRDRMVMMWD 63 67889****555999995555555568999*******9 PP == domain 2 score: 30.0 bits; conditional E-value: 3.7e-08 EEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 + + l GH vt+la+spd++ l++Gs+D+t+ +Wd tr|C9JWF1|C9JWF1_HUMAN 70 PRQQLCGH-AmvVTGLAVSPDSSQLCTGSRDNTLLLWD 106 667788**.6668************************9 PP >> tr|E7EW44|E7EW44_HUMAN Coronin OS=Homo sapiens GN=CORO1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.2 2.4e-06 0.0002 8 37 .. 79 110 .. 73 111 .. 0.86 2 ! 16.8 0.0 0.00057 0.047 3 38 .] 124 161 .. 122 161 .. 0.84 3 ! 15.4 0.4 0.0016 0.13 10 38 .] 175 204 .. 170 204 .. 0.87 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 2.4e-06 ESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W tr|E7EW44|E7EW44_HUMAN 79 CGHtGPVLDIDWCPHNDEViASGSEDCTVMVW 110 59*888************73699********* PP == domain 2 score: 16.8 bits; conditional E-value: 0.00057 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ v iW+ tr|E7EW44|E7EW44_HUMAN 124 PVVVLEGHtKRVGIIAWHPTARNVLlsAGC-DNVVLIWN 161 67899***999*9999*******6342677.*******8 PP == domain 3 score: 15.4 bits; conditional E-value: 0.0016 SSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriWd 38 H + ++ ++++++g++++s+++D++vri d tr|E7EW44|E7EW44_HUMAN 175 H-PdlIYNVSWNHNGSLFCSACKDKSVRIID 204 5.235999********************966 PP >> sp|Q92636-2|FAN_HUMAN Isoform 2 of Protein FAN OS=Homo sapiens GN=NSMAF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.042 3.4 6 37 .. 656 688 .. 650 689 .. 0.86 2 ! 16.1 1.9 0.00092 0.074 4 38 .] 738 771 .. 735 771 .. 0.86 3 ? 10.0 0.1 0.078 6.3 10 38 .] 793 822 .. 780 822 .. 0.78 4 ! 13.4 0.5 0.0067 0.54 3 36 .. 828 862 .. 826 864 .. 0.80 5 ? 3.6 0.2 8.7 7.1e+02 20 38 .] 885 903 .. 871 903 .. 0.84 6 ? 12.6 0.1 0.012 0.95 8 38 .] 914 945 .. 908 945 .. 0.78 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.042 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++ H vt++ +s++g+ +++ s D t++++ sp|Q92636-2|FAN_HUMAN 656 HYKIHkEAVTGITVSRNGSSVFTTSQDSTLKMF 688 68889555**********************986 PP == domain 2 score: 16.1 bits; conditional E-value: 0.00092 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + tl GH + v+ ++++++ + s+s+D tv++W+ sp|Q92636-2|FAN_HUMAN 738 QDTLMGHdDAVSKICWHDNRLY--SASWDSTVKVWS 771 66888**666****99999999..8**********5 PP == domain 3 score: 10.0 bits; conditional E-value: 0.078 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H sv ++ + +++l+sG++ gtv iWd sp|Q92636-2|FAN_HUMAN 793 HdVSVDTISLNAASTLLVSGTKEGTVNIWD 822 6444666668888999*************9 PP == domain 4 score: 13.4 bits; conditional E-value: 0.0067 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvri 36 +++ + Hs+ v++ afspd++ ++s + Dg + + sp|Q92636-2|FAN_HUMAN 828 LMHQIPCHSGiVCDTAFSPDSRHVLSTGTDGCLNV 862 5677889*7757***********986555**9977 PP == domain 5 score: 3.6 bits; conditional E-value: 8.7 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 dg+ ++sGs g + +Wd sp|Q92636-2|FAN_HUMAN 885 WDGNSVLSGSQSGELLVWD 903 4777788***********9 PP == domain 6 score: 12.6 bits; conditional E-value: 0.012 ESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 GH + vt++ w +++G++D+ + +W+ sp|Q92636-2|FAN_HUMAN 914 QGHtGAVTCI-------WmneqcssIITGGEDRQIIFWK 945 69*777****.......44444445899**********6 PP >> tr|H3BPU5|H3BPU5_HUMAN Target of rapamycin complex subunit LST8 OS=Homo sapiens GN=MLST8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.024 1.9 24 37 .. 14 27 .. 7 28 .. 0.82 2 ! 15.8 0.0 0.0012 0.099 3 38 .] 34 69 .. 32 69 .. 0.86 3 ! 25.3 0.1 1.1e-06 9.3e-05 5 38 .] 79 113 .. 75 113 .. 0.83 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.024 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W tr|H3BPU5|H3BPU5_HUMAN 14 ILATAGYDHTVRFW 27 5888888******* PP == domain 2 score: 15.8 bits; conditional E-value: 0.0012 EEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 c+rt H s v++l + pd +++a+++ +++r++d tr|H3BPU5|H3BPU5_HUMAN 34 CTRTVQ-HqdSQVNALEVTPDRSMIAAAG-YQHIRMYD 69 788875.75444**************99*.******98 PP == domain 3 score: 25.3 bits; conditional E-value: 1.1e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++G +++ s+ f+ dg+w+ +G++D+t riWd tr|H3BPU5|H3BPU5_HUMAN 79 ISYDGVnKNIASVGFHEDGRWMYTGGEDCTARIWD 113 55555545688999********************9 PP >> tr|Q5JP01|Q5JP01_HUMAN Histone-binding protein RBBP7 (Fragment) OS=Homo sapiens GN=RBBP7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.4 0.0032 0.26 15 38 .] 101 125 .. 86 125 .. 0.60 2 ! 15.2 0.2 0.0018 0.14 6 38 .] 141 175 .. 137 175 .. 0.75 3 ! 19.1 0.0 0.00011 0.0087 3 33 .. 184 216 .. 182 239 .. 0.85 4 ? 12.5 0.3 0.013 1.1 14 38 .] 259 284 .. 249 284 .. 0.79 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 0.0032 EEEEETTSSE...EEEEETTSEEEEEE CS WD40 15 slafspdgaw...lasGsdDgtvriWd 38 +l+++++ + l+s+sdD+tv +Wd tr|Q5JP01|Q5JP01_HUMAN 101 GLSWNSN--LsghLLSASDDHTVCLWD 125 4432222..1334668999*******9 PP == domain 2 score: 15.2 bits; conditional E-value: 0.0018 EEESSSS.EEEEEEETTSSEEEEEE..TTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGs..dDgtvriWd 38 ++tGHs v ++a++ + l+ Gs dD++++iWd tr|Q5JP01|Q5JP01_HUMAN 141 IFTGHSAvVEDVAWHLLHESLF-GSvaDDQKLMIWD 175 79***7767***5544444488.76458*******9 PP == domain 3 score: 19.1 bits; conditional E-value: 0.00011 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgt 33 + + ++H v++l+f+p++ ++ a+Gs D+ tr|Q5JP01|Q5JP01_HUMAN 184 PSHLVDAHtAEVNCLSFNPYSEFIlATGSADKV 216 5677789*666************6379999986 PP == domain 4 score: 12.5 bits; conditional E-value: 0.013 EEEEEETTSSEEE.EEETTSEEEEEE CS WD40 14 tslafspdgawla.sGsdDgtvriWd 38 + + +sp++ ++ s++ D+ + +Wd tr|Q5JP01|Q5JP01_HUMAN 259 HRVHWSPHNETILaSSGTDRRLNVWD 284 6789*******7525567*******9 PP >> tr|I3L426|I3L426_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.1 0.1 4e-09 3.3e-07 4 37 .. 83 118 .. 80 119 .. 0.88 2 ? 7.5 0.0 0.48 39 16 38 .] 145 167 .. 136 167 .. 0.76 3 ? 11.6 0.0 0.026 2.1 2 35 .. 172 206 .] 171 206 .] 0.86 Alignments for each domain: == domain 1 score: 33.1 bits; conditional E-value: 4e-09 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriW 37 + +l Hs+ vt+l+fsp ++l a+Gs D+tv++W tr|I3L426|I3L426_HUMAN 83 VAHLGCHSDlVTDLDFSPFDDFLlATGSADRTVKLW 118 679999*8889***********7369********** PP == domain 2 score: 7.5 bits; conditional E-value: 0.48 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 l+f+p ++ ++ + tv++Wd tr|I3L426|I3L426_HUMAN 145 LQFHPTSDGILVSAAGTTVKVWD 167 568888888654544*******9 PP == domain 3 score: 11.6 bits; conditional E-value: 0.026 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvr 35 q+l++l +H++ v s +s+dga++ ++++D+ +r tr|I3L426|I3L426_HUMAN 172 QPLTELAAHGDlVQSAVWSRDGALVGTACKDKQLR 206 89999****77899999*******85668899987 PP >> tr|F5H390|F5H390_HUMAN Coronin OS=Homo sapiens GN=CORO1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.2 2.3e-06 0.00019 8 37 .. 79 110 .. 73 111 .. 0.86 2 ! 16.8 0.0 0.00055 0.045 3 38 .] 124 161 .. 122 161 .. 0.84 3 ! 15.5 0.4 0.0015 0.12 10 38 .] 175 204 .. 170 204 .. 0.87 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 2.3e-06 ESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W tr|F5H390|F5H390_HUMAN 79 CGHtGPVLDIDWCPHNDEViASGSEDCTVMVW 110 59*888************73699********* PP == domain 2 score: 16.8 bits; conditional E-value: 0.00055 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ v iW+ tr|F5H390|F5H390_HUMAN 124 PVVVLEGHtKRVGIIAWHPTARNVLlsAGC-DNVVLIWN 161 67899***999*9999*******6342677.*******8 PP == domain 3 score: 15.5 bits; conditional E-value: 0.0015 SSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriWd 38 H + ++ ++++++g++++s+++D++vri d tr|F5H390|F5H390_HUMAN 175 H-PdlIYNVSWNHNGSLFCSACKDKSVRIID 204 5.235999********************966 PP >> sp|Q96KV7-7|WDR90_HUMAN Isoform 4 of WD repeat-containing protein 90 OS=Homo sapiens GN=WDR90 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.0 2.2e-05 0.0017 2 37 .. 15 61 .. 14 61 .. 0.84 2 ? 7.8 0.0 0.4 32 18 37 .. 90 109 .. 73 110 .. 0.71 3 ! 13.1 0.0 0.0081 0.66 10 34 .. 121 148 .. 114 150 .. 0.80 4 ? 4.9 0.0 3.2 2.6e+02 7 37 .. 264 294 .. 260 295 .. 0.80 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 2.2e-05 EEEEEEE....SS.SS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtlt....GH.ss......vtslafspdgawlasGsdDgtvriW 37 +clr +t H ++ v+ + fsp + a++s+Dg+vr+W sp|Q96KV7-7|WDR90_HUMAN 15 KCLRPFTlprgQHpQPsygfpqVNEVVFSPGESHCATCSEDGSVRVW 61 6888876666556655778899************************* PP == domain 2 score: 7.8 bits; conditional E-value: 0.4 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 p+++ la+G Dg++ri+ sp|Q96KV7-7|WDR90_HUMAN 90 GRPEQQRLAAGYGDGSLRIF 109 5677777****55******7 PP == domain 3 score: 13.1 bits; conditional E-value: 0.0081 S.SSE..EEEEEETTSSEEEEEETTSEE CS WD40 10 H.ssv..tslafspdgawlasGsdDgtv 34 H +v t +afs dg+ ++sG++Dg v sp|Q96KV7-7|WDR90_HUMAN 121 HpHPValTTVAFSTDGQTVLSGDKDGLV 148 5335444******************976 PP == domain 4 score: 4.9 bits; conditional E-value: 3.2 EESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 + GH + v +l+ f p+ ++l+++ + + +W sp|Q96KV7-7|WDR90_HUMAN 264 FAGHdNAV-HLCrFTPSARLLFTAA-RNEILVW 294 77**8889.6666********9988.7777776 PP >> sp|Q96EE3|SEH1_HUMAN Nucleoporin SEH1 OS=Homo sapiens GN=SEH1L PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.9 1.7e-05 0.0014 10 38 .] 11 40 .. 5 40 .. 0.92 2 ? 11.6 2.6 0.026 2.1 2 37 .. 48 86 .. 47 87 .. 0.85 3 ? 11.5 0.0 0.027 2.1 11 37 .. 114 142 .. 96 143 .. 0.76 4 ? 4.0 0.6 6.4 5.1e+02 13 32 .. 165 189 .. 152 190 .. 0.75 5 ! 22.4 1.9 9.4e-06 0.00076 6 38 .] 273 306 .. 268 306 .. 0.87 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.7e-05 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H++ +++++f+ +g+ +a++s D++v++Wd sp|Q96EE3|SEH1_HUMAN 11 HKDlIHDVSFDFHGRRMATCSSDQSVKVWD 40 87789***************88*******9 PP == domain 2 score: 11.6 bits; conditional E-value: 0.026 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriW 37 c+ ++++H +sv+ + +w las+s D+t +W sp|Q96EE3|SEH1_HUMAN 48 HCTASWKTHsGSVWRV------TWahpefgqvLASCSFDRTAAVW 86 79999****777****......777777777799********999 PP == domain 3 score: 11.5 bits; conditional E-value: 0.027 SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 11 ssvtslafspdgaw..lasGsdDgtvriW 37 +svt+++f p + la++s Dg vri+ sp|Q96EE3|SEH1_HUMAN 114 TSVTDVKFAPKHMGlmLATCSADGIVRIY 142 459999766665555579**********8 PP == domain 4 score: 4.0 bits; conditional E-value: 6.4 EEEEEEETTSSE.....EEEEETTS CS WD40 13 vtslafspdgaw.....lasGsdDg 32 ++++++p+++ +a GsdD sp|Q96EE3|SEH1_HUMAN 165 CSCISWNPSSSRahspmIAVGSDDS 189 57999999999999998889*9885 PP == domain 5 score: 22.4 bits; conditional E-value: 9.4e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ H s v+ ++++ g+ las++dDg vr+W+ sp|Q96EE3|SEH1_HUMAN 273 QFDNHnSQVWRVSWNITGTVLASSGDDGCVRLWK 306 57889555**************999********6 PP >> sp|Q86W42-2|THOC6_HUMAN Isoform 2 of THO complex subunit 6 homolog OS=Homo sapiens GN=THOC6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 1.8 1.5e+02 13 36 .. 3 26 .. 2 28 .. 0.82 2 ? 10.9 0.0 0.043 3.5 2 37 .. 43 76 .. 42 76 .. 0.86 3 ! 25.7 0.0 8.8e-07 7.1e-05 3 38 .] 136 172 .. 134 172 .. 0.84 4 ? 5.8 0.3 1.8 1.4e+02 10 37 .. 194 220 .. 183 221 .. 0.79 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 1.8 EEEEEEETTSSEEEEEETTSEEEE CS WD40 13 vtslafspdgawlasGsdDgtvri 36 + s+++sp g++la+G g + i sp|Q86W42-2|THOC6_HUMAN 3 IFSQSVSPCGKFLAAGNNYGQIAI 26 678999********9977877766 PP == domain 2 score: 10.9 bits; conditional E-value: 0.043 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++ t+ +H ++v+s+ +s d ++l s++ Dg v+ W sp|Q86W42-2|THOC6_HUMAN 43 KPVVTFQAHdGPVYSM-VSTDRHLL-SAG-DGEVKAW 76 68899****888****.88888887.689.****988 PP == domain 3 score: 25.7 bits; conditional E-value: 8.8e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r+l+GH + +++la ++ ++sG++Dg vr+Wd sp|Q86W42-2|THOC6_HUMAN 136 FTRVLRGHtDYIHCLALRERSPEVLSGGEDGAVRLWD 172 5799****555****7666666699***********9 PP == domain 4 score: 5.8 bits; conditional E-value: 1.8 SSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriW 37 H++ + +l d++w+++G+ + + +W sp|Q86W42-2|THOC6_HUMAN 194 HNGrwIGCL--ATDSDWMVCGG-GPALTLW 220 644569999..88******999.8877777 PP >> sp|Q149M9-3|NWD1_HUMAN Isoform 3 of NACHT and WD repeat domain-containing protein 1 OS=Homo sapiens GN=NWD1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.088 7.2 6 38 .] 863 896 .. 858 896 .. 0.87 2 ! 17.6 0.1 0.00031 0.025 4 38 .] 903 938 .. 900 938 .. 0.87 3 ? 4.8 0.1 3.6 2.9e+02 13 38 .] 1003 1028 .. 988 1028 .. 0.76 4 ! 13.6 0.0 0.0059 0.48 7 38 .] 1384 1416 .. 1379 1416 .. 0.93 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.088 EEE.SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tlt.GHssvtslafspdgawlasGsdDgtvriWd 38 tl+ H+++t++a+ + ++l+ G+ Dg +Wd sp|Q149M9-3|NWD1_HUMAN 863 TLSgCHKGITAMAWGVEEKLLVIGTQDGIMAVWD 896 56635699****99999999*************9 PP == domain 2 score: 17.6 bits; conditional E-value: 0.00031 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ ltGH + v++++ g++ a s+s+D t+++W+ sp|Q149M9-3|NWD1_HUMAN 903 IHMLTGHtGEVRCVKIFAKGTL-AnSASKDYTLHLWN 938 7889***777****99999999.87789********8 PP == domain 3 score: 4.8 bits; conditional E-value: 3.6 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++a+ ++a l++ s+Dg v +W+ sp|Q149M9-3|NWD1_HUMAN 1003 WMCMAVLASQATLLTVSRDGVVSLWS 1028 4588888888899999*********5 PP == domain 4 score: 13.6 bits; conditional E-value: 0.0059 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++H s v ++ +s+ ++++sGs+D + +Wd sp|Q149M9-3|NWD1_HUMAN 1384 LETHrSRVACVEVSHKEQLVVSGSEDALLCLWD 1416 679*899*************************9 PP >> sp|Q04725-3|TLE2_HUMAN Isoform 3 of Transducin-like enhancer protein 2 OS=Homo sapiens GN=TLE2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.3 0.0007 0.057 3 38 .] 464 498 .. 462 498 .. 0.89 2 ? 6.6 0.0 0.92 75 12 38 .] 519 545 .. 509 545 .. 0.91 3 ! 14.0 0.2 0.0043 0.35 14 38 .] 565 589 .. 555 589 .. 0.85 4 ! 15.7 0.6 0.0013 0.1 4 38 .] 596 631 .. 593 631 .. 0.89 5 ? 7.0 0.0 0.73 59 6 34 .. 637 668 .. 633 670 .. 0.76 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 0.0007 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +l+tl +H+ v+++ s + + + +G+ +g v++Wd sp|Q04725-3|TLE2_HUMAN 464 QLHTL-AHGEvVCAVTISGSTQHVYTGG-KGCVKVWD 498 67888.8*6657****************.*******9 PP == domain 2 score: 6.6 bits; conditional E-value: 0.92 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd sp|Q04725-3|TLE2_HUMAN 519 YIRSCKLLPDGRSLIVGGEASTLSIWD 545 499999********************9 PP == domain 3 score: 14.0 bits; conditional E-value: 0.0043 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la+spd + +s++ Dg++ +Wd sp|Q04725-3|TLE2_HUMAN 565 YALAVSPDAKVCFSCCSDGNIVVWD 589 6899*******887755*******9 PP == domain 4 score: 15.7 bits; conditional E-value: 0.0013 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r + GH ++ ++++ s++g+ l +G+ D+tvr Wd sp|Q04725-3|TLE2_HUMAN 596 VRQFQGHtDGASCIDISDYGTRLWTGGLDNTVRCWD 631 7889***7779***********747999*******9 PP == domain 5 score: 7.0 bits; conditional E-value: 0.73 EEESS.SS..EEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ss..vtslafspdgawlasGsdDgtv 34 l H +s + sl +p+++wla G++ +v sp|Q04725-3|TLE2_HUMAN 637 QLQQHdFSsqIFSLGHCPNQDWLAVGMESSNV 668 5667863347**************99866555 PP >> sp|Q96S15|WDR24_HUMAN WD repeat-containing protein 24 OS=Homo sapiens GN=WDR24 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.027 2.2 7 38 .] 178 211 .. 172 211 .. 0.82 2 ! 27.3 0.2 2.7e-07 2.2e-05 2 38 .] 328 366 .. 327 366 .. 0.85 3 ? 9.5 0.1 0.12 9.6 12 38 .] 383 412 .. 368 412 .. 0.71 4 ? 5.5 0.0 2.1 1.7e+02 7 34 .. 423 453 .. 418 455 .. 0.83 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.027 EESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawla.sGsdDgtvriWd 38 +t H+ v+ ++f+p a ++ sGs Dg + +d sp|Q96S15|WDR24_HUMAN 178 FTEHKRtVNKVCFHPTEAHVLlSGSQDGFMKCFD 211 7899556************644******888766 PP == domain 2 score: 27.3 bits; conditional E-value: 2.7e-07 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +c r +t+H ++v +++++p+ + la+G++D+ v++Wd sp|Q96S15|WDR24_HUMAN 328 RCERMFTAHnGPVFCCDWHPEDRGwLATGGRDKMVKVWD 366 58999****777****966666556*************9 PP == domain 3 score: 9.5 bits; conditional E-value: 0.12 SEEEEEEETTSSE.EEEEET..TSEEEEEE CS WD40 12 svtslafspdgaw.lasGsd..DgtvriWd 38 sv +++ p+ + la++s+ D+++++Wd sp|Q96S15|WDR24_HUMAN 383 SVARVKWRPECRHhLATCSMmvDHNIYVWD 412 3555658888888568998556*******9 PP == domain 4 score: 5.5 bits; conditional E-value: 2.1 EESSSSE.EEEE..EETTSSEEEEEETTSEE CS WD40 7 ltGHssv.tsla..fspdgawlasGsdDgtv 34 ++ H +v t++a ++d ++l+sGs+D ++ sp|Q96S15|WDR24_HUMAN 423 FEEHRDVtTGIAwrHPHDPSFLLSGSKDSSL 453 667877988998888999999*******987 PP >> sp|O60336-5|MABP1_HUMAN Isoform 5 of Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens GN=MAPKBP1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.2 4e-05 0.0032 9 38 .] 83 120 .. 75 120 .. 0.73 2 ! 16.6 0.0 0.00064 0.052 4 37 .. 127 163 .. 125 163 .. 0.79 3 ! 16.4 0.1 0.00077 0.062 12 37 .. 178 203 .. 167 203 .. 0.89 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 4e-05 SS..SS....EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 9 GH..ss....vtslafspdgawlasG..sdDgtvriWd 38 H +s +t+lafspdg++l++G + + vr+Wd sp|O60336-5|MABP1_HUMAN 83 HHilNSsrktITALAFSPDGKYLVTGesGHMPAVRVWD 120 3455334666**************98754588888887 PP == domain 2 score: 16.6 bits; conditional E-value: 0.00064 EEEEESSSS.EEEEEEETTSSEEEEEET..TSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsd..DgtvriW 37 + +l H+ v ++afsp+ ++++s ++ D v +W sp|O60336-5|MABP1_HUMAN 127 VAELQEHKYgVACVAFSPSAKYIVSVGYqhDMIVNVW 163 5678899555************99755223****999 PP == domain 3 score: 16.4 bits; conditional E-value: 0.00077 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 s vt+++fs d +++++++ ++++++W sp|O60336-5|MABP1_HUMAN 178 SrVTAVSFSEDCSYFVTAG-NRHIKFW 203 34*****************.******* PP >> tr|J3QRV4|J3QRV4_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.3 1.4e-06 0.00011 8 37 .. 78 109 .. 71 110 .. 0.86 2 ! 18.8 0.1 0.00014 0.011 2 38 .] 122 160 .. 121 160 .. 0.84 3 ! 13.3 0.2 0.007 0.57 10 33 .. 174 198 .] 164 198 .] 0.84 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 1.4e-06 ESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawla.sGsdDgtvriW 37 tGH +v +++++p+++ ++ s+sdD t+++W tr|J3QRV4|J3QRV4_HUMAN 78 TGHtAPVLDIDWCPHNDNVIaSASDDTTIMVW 109 7**888************762679******** PP == domain 2 score: 18.8 bits; conditional E-value: 0.00014 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v l+++p + l++G+ D+ + iW+ tr|J3QRV4|J3QRV4_HUMAN 122 EPIITLEGHsKRVGILSWHPTARNvlLSAGG-DNVIIIWN 160 57899****888*9999*******4334778.*******8 PP == domain 3 score: 13.3 bits; conditional E-value: 0.007 SSS..EEEEEEETTSSEEEEEETTSE CS WD40 10 Hss..vtslafspdgawlasGsdDgt 33 H + ++s++++++g++la+ ++D+t tr|J3QRV4|J3QRV4_HUMAN 174 H-PdvIHSVCWNSNGSLLATTCKDKT 198 6.3347*************9999997 PP >> tr|G3V3F1|G3V3F1_HUMAN Neural cell expressed, developmentally down-regulated 1, isoform CRA_c OS=Homo sapiens GN=NED # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.5 0.0052 0.42 8 34 .. 36 67 .. 30 68 .. 0.71 2 ? 10.5 0.0 0.057 4.6 14 38 .] 88 112 .. 81 112 .. 0.93 3 ? 10.9 0.2 0.04 3.3 5 32 .. 120 148 .. 116 154 .. 0.83 4 ? 7.1 0.2 0.64 52 8 38 .] 164 198 .. 155 198 .. 0.77 5 ? 7.9 0.0 0.38 31 3 38 .] 248 283 .. 246 283 .. 0.79 6 ? 5.2 0.1 2.6 2.1e+02 2 20 .. 289 308 .. 288 324 .. 0.84 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.0052 ESS.SS..EEEEEEETTSSEEEEE..ETTSEE CS WD40 8 tGH.ss..vtslafspdgawlasG..sdDgtv 34 H s+ ++s+++s+++++l+++ s D+ v tr|G3V3F1|G3V3F1_HUMAN 36 NPHtSPhgISSICWSSNNNFLVTAssSGDKIV 67 55654466*************86522348776 PP == domain 2 score: 10.5 bits; conditional E-value: 0.057 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 t++ ++ + +l+sG+ ++tv iWd tr|G3V3F1|G3V3F1_HUMAN 88 TCVNLNSTSMYLVSGGLNNTVNIWD 112 79999999999*************9 PP == domain 3 score: 10.9 bits; conditional E-value: 0.04 EEEESSSS.EEEEEEETTSSEEEEEETTS CS WD40 5 rtltGHss.vtslafspdgawlasGsdDg 32 r+l+ H++ vt++ ++ + ++asGs g tr|G3V3F1|G3V3F1_HUMAN 120 RSLKDHKDqVTCVTYNWNDCYIASGSLSG 148 68999*555******99********9655 PP == domain 4 score: 7.1 bits; conditional E-value: 0.64 ESS.SS..EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 8 tGH.ss..vtslafspdgawlasG..sdDgtvriWd 38 GH s+ v++l++s ++ l+ G sd+g v +Wd tr|G3V3F1|G3V3F1_HUMAN 164 FGHgSNqsVRHLKYSLFKKSLL-GsvSDNGIVTLWD 198 39973367****9998899999.53579*******9 PP == domain 5 score: 7.9 bits; conditional E-value: 0.38 EEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtvriWd 38 +++tl + ++ t+++f pdga la Gs g+++ +d tr|G3V3F1|G3V3F1_HUMAN 248 LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYD 283 56777666779***************8677776665 PP == domain 6 score: 5.2 bits; conditional E-value: 2.6 EEEEEEESS.SSEEEEEEET CS WD40 2 qclrtltGH.ssvtslafsp 20 ++++t+++H +sv ++af+ tr|G3V3F1|G3V3F1_HUMAN 289 SPVKTISAHkTSVQCIAFQY 308 6899*****888****8764 PP >> tr|E9PKB8|E9PKB8_HUMAN WD repeat-containing protein KIAA1875 OS=Homo sapiens GN=KIAA1875 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.32 26 12 37 .. 294 319 .. 287 320 .. 0.70 2 ! 22.4 0.0 9.8e-06 0.00079 3 38 .] 325 361 .. 323 361 .. 0.91 3 ? 8.1 0.1 0.33 26 8 37 .. 594 623 .. 587 624 .. 0.68 4 ! 13.5 0.3 0.0063 0.51 8 37 .. 689 716 .. 682 717 .. 0.83 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.32 SEEEEEEETTSSE......EEEEETTSEEEEE CS WD40 12 svtslafspdgaw......lasGsdDgtvriW 37 +++l a+ ++++s+D tv++W tr|E9PKB8|E9PKB8_HUMAN 294 TISDL------AYceeveaMVTASRDSTVKVW 319 46777......44444444679999******* PP == domain 2 score: 22.4 bits; conditional E-value: 9.8e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ GH ++vt++ + p+ ++++s+s Dgt+r Wd tr|E9PKB8|E9PKB8_HUMAN 325 IRMVFVGHtGPVTAMTVLPNTTLVLSASQDGTLRTWD 361 567899**888*************************9 PP == domain 3 score: 8.1 bits; conditional E-value: 0.33 ESSSS..EEEEEEETTSSE...EEEEETTSEEEEE CS WD40 8 tGHss..vtslafspdgaw...lasGsdDgtvriW 37 ++Hs+ v ++ ++w ++sG+ D tv++W tr|E9PKB8|E9PKB8_HUMAN 594 EAHSPgpVVAI----ASTWnsiVSSGG-DLTVKMW 623 58844457788....445566467889.******* PP == domain 4 score: 13.5 bits; conditional E-value: 0.0063 ESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriW 37 t H +t+l+ +p ++ a++s D+tvriW tr|E9PKB8|E9PKB8_HUMAN 689 TDH--ITGLCCCPTLKLYACSSLDCTVRIW 716 567..999999999999888899******* PP >> sp|A6NE52-2|K1875_HUMAN Isoform 2 of WD repeat-containing protein KIAA1875 OS=Homo sapiens GN=KIAA1875 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.32 26 12 37 .. 294 319 .. 287 320 .. 0.70 2 ! 22.4 0.0 9.8e-06 0.00079 3 38 .] 325 361 .. 323 361 .. 0.91 3 ? 8.1 0.1 0.33 26 8 37 .. 594 623 .. 587 624 .. 0.68 4 ! 13.5 0.3 0.0063 0.51 8 37 .. 689 716 .. 682 717 .. 0.83 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.32 SEEEEEEETTSSE......EEEEETTSEEEEE CS WD40 12 svtslafspdgaw......lasGsdDgtvriW 37 +++l a+ ++++s+D tv++W sp|A6NE52-2|K1875_HUMAN 294 TISDL------AYceeveaMVTASRDSTVKVW 319 46777......44444444679999******* PP == domain 2 score: 22.4 bits; conditional E-value: 9.8e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ GH ++vt++ + p+ ++++s+s Dgt+r Wd sp|A6NE52-2|K1875_HUMAN 325 IRMVFVGHtGPVTAMTVLPNTTLVLSASQDGTLRTWD 361 567899**888*************************9 PP == domain 3 score: 8.1 bits; conditional E-value: 0.33 ESSSS..EEEEEEETTSSE...EEEEETTSEEEEE CS WD40 8 tGHss..vtslafspdgaw...lasGsdDgtvriW 37 ++Hs+ v ++ ++w ++sG+ D tv++W sp|A6NE52-2|K1875_HUMAN 594 EAHSPgpVVAI----ASTWnsiVSSGG-DLTVKMW 623 58844457788....445566467889.******* PP == domain 4 score: 13.5 bits; conditional E-value: 0.0063 ESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriW 37 t H +t+l+ +p ++ a++s D+tvriW sp|A6NE52-2|K1875_HUMAN 689 TDH--ITGLCCCPTLKLYACSSLDCTVRIW 716 567..999999999999888899******* PP >> sp|Q6ZNJ1-3|NBEL2_HUMAN Isoform 3 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.035 2.8 13 36 .. 2430 2456 .. 2415 2456 .. 0.74 2 ! 23.0 0.3 6.1e-06 0.00049 1 37 [. 2462 2499 .. 2462 2500 .. 0.90 3 ! 17.6 0.0 0.00033 0.026 2 36 .. 2514 2549 .. 2513 2550 .. 0.92 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.035 E..EEEEEETTSSEEEEE.ETTSEEEE CS WD40 13 v..tslafspdgawlasG.sdDgtvri 36 v +la+ pdg++l+sG ++Dg++r+ sp|Q6ZNJ1-3|NBEL2_HUMAN 2430 VsgQALAVAPDGKLLFSGgHWDGSLRV 2456 6333566**********9569****97 PP == domain 2 score: 23.0 bits; conditional E-value: 6.1e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l l+ H + vt+la + g +l+sGs+D t+++W sp|Q6ZNJ1-3|NBEL2_HUMAN 2462 GKLLSQLSCHlDVVTCLALDTCGIYLISGSRDTTCMVW 2499 5788899***5558************************ PP == domain 3 score: 17.6 bits; conditional E-value: 0.00033 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++++l GH v+++a s + ++ +sGs+Dgtv i sp|Q6ZNJ1-3|NBEL2_HUMAN 2514 KPVQVLYGHgAAVSCVAISTELDMAVSGSEDGTVII 2549 68999****766*********************976 PP >> sp|Q8TDJ6|DMXL2_HUMAN DmX-like protein 2 OS=Homo sapiens GN=DMXL2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.8 0.021 1.7 9 37 .. 168 197 .. 160 197 .. 0.71 2 ? 10.2 0.2 0.069 5.6 6 37 .. 227 268 .. 222 268 .. 0.79 3 ? 7.5 0.0 0.5 40 9 38 .] 998 1028 .. 991 1028 .. 0.70 4 ? 4.3 0.6 5 4.1e+02 8 38 .] 2849 2883 .. 2843 2883 .. 0.72 5 ? 9.3 0.1 0.13 11 3 38 .] 2892 2928 .. 2890 2928 .. 0.85 6 ! 21.1 0.0 2.5e-05 0.002 2 37 .. 2933 2969 .. 2932 2970 .. 0.94 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.021 SSSSEEEEE.....EETTSSEEEEEE.TTSEEEEE CS WD40 9 GHssvtsla.....fspdgawlasGs.dDgtvriW 37 + ++ +spdg ++a+++ dD+ +++W sp|Q8TDJ6|DMXL2_HUMAN 168 TS-----VSvhlmeWSPDGEYFATAGkDDCLLKVW 197 33.....2344667*********88757******* PP == domain 2 score: 10.2 bits; conditional E-value: 0.069 EEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 ++ +H vt++++ + +++ l+s++ Dg +r+W sp|Q8TDJ6|DMXL2_HUMAN 227 VYLAHpRAVTGFSWRKTSKYmprgsvcnvlLTSCH-DGVCRLW 268 56689555999998888888999999998566777.******* PP == domain 3 score: 7.5 bits; conditional E-value: 0.5 SS.SS.....EEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 9 GH.ss.....vtslafspdgawla..sGsdDgtvriWd 38 GH ss v +l ++l+ ++s D++vr+W+ sp|Q8TDJ6|DMXL2_HUMAN 998 GHlSSssiypV-CL-----APYLVvtTCS-DNKVRFWK 1028 88844464444.88.....6775434899.*******6 PP == domain 4 score: 4.3 bits; conditional E-value: 5 ESS.SSEEEEEEETTSSEEEEEE...TTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGs...dDgtvriWd 38 H + +++af +++++a+++ d+++v +Wd sp|Q8TDJ6|DMXL2_HUMAN 2849 QCHsKATSDFAFITSSSLVATSGhsnDNRNVCLWD 2883 567444467778888899996543678*******9 PP == domain 5 score: 9.3 bits; conditional E-value: 0.13 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++ +t H++ t l++ p +++l+sG+++g+v i+d sp|Q8TDJ6|DMXL2_HUMAN 2892 LIHGFTCHDHgATVLQYAPKQQLLISGGRKGHVCIFD 2928 57778999445888899******************98 PP == domain 6 score: 21.1 bits; conditional E-value: 2.5e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 q+++t+ +H s + +la +p+ ++++Gs g++++W sp|Q8TDJ6|DMXL2_HUMAN 2933 QLIHTFQAHdSAIKALALDPYEEYFTTGSAEGNIKVW 2969 899******777************************* PP >> sp|Q8TDJ6-3|DMXL2_HUMAN Isoform 3 of DmX-like protein 2 OS=Homo sapiens GN=DMXL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.8 0.021 1.7 9 37 .. 168 197 .. 160 197 .. 0.71 2 ? 10.2 0.2 0.069 5.6 6 37 .. 227 268 .. 222 268 .. 0.79 3 ? 7.5 0.0 0.5 40 9 38 .] 998 1028 .. 991 1028 .. 0.70 4 ? 4.3 0.6 5 4.1e+02 8 38 .] 2850 2884 .. 2844 2884 .. 0.72 5 ? 9.3 0.1 0.13 11 3 38 .] 2893 2929 .. 2891 2929 .. 0.85 6 ! 21.1 0.0 2.5e-05 0.002 2 37 .. 2934 2970 .. 2933 2971 .. 0.94 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.021 SSSSEEEEE.....EETTSSEEEEEE.TTSEEEEE CS WD40 9 GHssvtsla.....fspdgawlasGs.dDgtvriW 37 + ++ +spdg ++a+++ dD+ +++W sp|Q8TDJ6-3|DMXL2_HUMAN 168 TS-----VSvhlmeWSPDGEYFATAGkDDCLLKVW 197 33.....2344667*********88757******* PP == domain 2 score: 10.2 bits; conditional E-value: 0.069 EEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 ++ +H vt++++ + +++ l+s++ Dg +r+W sp|Q8TDJ6-3|DMXL2_HUMAN 227 VYLAHpRAVTGFSWRKTSKYmprgsvcnvlLTSCH-DGVCRLW 268 56689555999998888888999999998566777.******* PP == domain 3 score: 7.5 bits; conditional E-value: 0.5 SS.SS.....EEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 9 GH.ss.....vtslafspdgawla..sGsdDgtvriWd 38 GH ss v +l ++l+ ++s D++vr+W+ sp|Q8TDJ6-3|DMXL2_HUMAN 998 GHlSSssiypV-CL-----APYLVvtTCS-DNKVRFWK 1028 88844464444.88.....6775434899.*******6 PP == domain 4 score: 4.3 bits; conditional E-value: 5 ESS.SSEEEEEEETTSSEEEEEE...TTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGs...dDgtvriWd 38 H + +++af +++++a+++ d+++v +Wd sp|Q8TDJ6-3|DMXL2_HUMAN 2850 QCHsKATSDFAFITSSSLVATSGhsnDNRNVCLWD 2884 567444467778888899996543678*******9 PP == domain 5 score: 9.3 bits; conditional E-value: 0.13 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++ +t H++ t l++ p +++l+sG+++g+v i+d sp|Q8TDJ6-3|DMXL2_HUMAN 2893 LIHGFTCHDHgATVLQYAPKQQLLISGGRKGHVCIFD 2929 57778999445888899******************98 PP == domain 6 score: 21.1 bits; conditional E-value: 2.5e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 q+++t+ +H s + +la +p+ ++++Gs g++++W sp|Q8TDJ6-3|DMXL2_HUMAN 2934 QLIHTFQAHdSAIKALALDPYEEYFTTGSAEGNIKVW 2970 899******777************************* PP >> sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.035 2.9 13 36 .. 2460 2486 .. 2445 2486 .. 0.74 2 ! 23.0 0.3 6.2e-06 0.0005 1 37 [. 2492 2529 .. 2492 2530 .. 0.90 3 ! 17.5 0.0 0.00033 0.027 2 36 .. 2544 2579 .. 2543 2580 .. 0.92 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.035 E..EEEEEETTSSEEEEE.ETTSEEEE CS WD40 13 v..tslafspdgawlasG.sdDgtvri 36 v +la+ pdg++l+sG ++Dg++r+ sp|Q6ZNJ1|NBEL2_HUMAN 2460 VsgQALAVAPDGKLLFSGgHWDGSLRV 2486 6333566**********9569****97 PP == domain 2 score: 23.0 bits; conditional E-value: 6.2e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l l+ H + vt+la + g +l+sGs+D t+++W sp|Q6ZNJ1|NBEL2_HUMAN 2492 GKLLSQLSCHlDVVTCLALDTCGIYLISGSRDTTCMVW 2529 5788899***5558************************ PP == domain 3 score: 17.5 bits; conditional E-value: 0.00033 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++++l GH v+++a s + ++ +sGs+Dgtv i sp|Q6ZNJ1|NBEL2_HUMAN 2544 KPVQVLYGHgAAVSCVAISTELDMAVSGSEDGTVII 2579 68999****766*********************976 PP >> tr|H0Y764|H0Y764_HUMAN Neurobeachin-like protein 2 (Fragment) OS=Homo sapiens GN=NBEAL2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.025 2.1 13 36 .. 1748 1774 .. 1733 1774 .. 0.74 2 ! 23.5 0.3 4.4e-06 0.00036 1 37 [. 1780 1817 .. 1780 1818 .. 0.90 3 ! 18.0 0.0 0.00024 0.019 2 36 .. 1832 1867 .. 1831 1868 .. 0.92 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.025 E..EEEEEETTSSEEEEE.ETTSEEEE CS WD40 13 v..tslafspdgawlasG.sdDgtvri 36 v +la+ pdg++l+sG ++Dg++r+ tr|H0Y764|H0Y764_HUMAN 1748 VsgQALAVAPDGKLLFSGgHWDGSLRV 1774 6333566**********9569****97 PP == domain 2 score: 23.5 bits; conditional E-value: 4.4e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l l+ H + vt+la + g +l+sGs+D t+++W tr|H0Y764|H0Y764_HUMAN 1780 GKLLSQLSCHlDVVTCLALDTCGIYLISGSRDTTCMVW 1817 5788899***5558************************ PP == domain 3 score: 18.0 bits; conditional E-value: 0.00024 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++++l GH v+++a s + ++ +sGs+Dgtv i tr|H0Y764|H0Y764_HUMAN 1832 KPVQVLYGHgAAVSCVAISTELDMAVSGSEDGTVII 1867 68999****766*********************976 PP >> sp|Q9ULV4|COR1C_HUMAN Coronin-1C OS=Homo sapiens GN=CORO1C PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.6 2.1e-06 0.00017 7 37 .. 76 108 .. 69 109 .. 0.86 2 ! 15.4 0.1 0.0015 0.13 3 38 .] 122 159 .. 120 159 .. 0.83 3 ! 15.7 0.2 0.0013 0.1 10 38 .] 173 202 .. 167 202 .. 0.92 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 2.1e-06 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W sp|Q9ULV4|COR1C_HUMAN 76 VCGHtGPVLDIDWCPHNDQViASGSEDCTVMVW 108 459*888************73699********* PP == domain 2 score: 15.4 bits; conditional E-value: 0.0015 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ + iW+ sp|Q9ULV4|COR1C_HUMAN 122 PVVILEGHsKRVGIVAWHPTARNVLlsAGC-DNAIIIWN 159 77899***888*9999*******6332677.*******8 PP == domain 3 score: 15.7 bits; conditional E-value: 0.0013 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 Hs+ ++ ++++++g++++++s+D++vr+ d sp|Q9ULV4|COR1C_HUMAN 173 HSDmIYNVSWNRNGSLICTASKDKKVRVID 202 86789**********************965 PP >> sp|Q6RI45-4|BRWD3_HUMAN Isoform 4 of Bromodomain and WD repeat-containing protein 3 OS=Homo sapiens GN=BRWD3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.0 9.7e-05 0.0079 4 37 .. 25 61 .. 22 62 .. 0.84 2 ! 19.9 0.1 5.9e-05 0.0048 1 38 [] 125 164 .. 125 164 .. 0.71 3 ? 11.6 0.2 0.025 2 7 32 .. 180 203 .. 173 210 .. 0.80 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 9.7e-05 EEEEESS.SSEEEEEEETTSSEE..EEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawl..asGsdDgtvriW 37 + +l+ H + v +++f+ +g+ l +sGs+Dgt riW sp|Q6RI45-4|BRWD3_HUMAN 25 IAELESHtDKVVAVQFCNNGDSLrfVSGSRDGTARIW 61 678999*55599***9******6559*********** PP == domain 2 score: 19.9 bits; conditional E-value: 5.9e-05 TEEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 gq+l+tl+GH + v l + d++ ++s++ Dg++ iWd sp|Q6RI45-4|BRWD3_HUMAN 125 GQLLHTLSGHdDEVFVLEaHPFDQRIILSAGHDGNIFIWD 164 799*******5557666633555555556555*******9 PP == domain 3 score: 11.6 bits; conditional E-value: 0.025 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fspdg+ +a ++ D sp|Q6RI45-4|BRWD3_HUMAN 180 GQGHGAVFDCKFSPDGNHFA-CT-DS 203 569988************97.66.54 PP >> sp|Q9ULV4-2|COR1C_HUMAN Isoform 2 of Coronin-1C OS=Homo sapiens GN=CORO1C # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.6 2.1e-06 0.00017 7 37 .. 82 114 .. 75 115 .. 0.86 2 ! 15.4 0.1 0.0016 0.13 3 38 .] 128 165 .. 126 165 .. 0.83 3 ! 15.6 0.2 0.0013 0.11 10 38 .] 179 208 .. 173 208 .. 0.92 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 2.1e-06 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W sp|Q9ULV4-2|COR1C_HUMAN 82 VCGHtGPVLDIDWCPHNDQViASGSEDCTVMVW 114 459*888************73699********* PP == domain 2 score: 15.4 bits; conditional E-value: 0.0016 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ + iW+ sp|Q9ULV4-2|COR1C_HUMAN 128 PVVILEGHsKRVGIVAWHPTARNVLlsAGC-DNAIIIWN 165 77899***888*9999*******6332677.*******8 PP == domain 3 score: 15.6 bits; conditional E-value: 0.0013 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 Hs+ ++ ++++++g++++++s+D++vr+ d sp|Q9ULV4-2|COR1C_HUMAN 179 HSDmIYNVSWNRNGSLICTASKDKKVRVID 208 86789**********************965 PP >> tr|J3QSX4|J3QSX4_HUMAN Mitotic checkpoint protein BUB3 OS=Homo sapiens GN=BUB3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.0 0.00071 0.058 12 38 .] 16 43 .. 4 43 .. 0.85 2 ? 8.8 0.1 0.19 15 9 37 .. 54 82 .. 47 83 .. 0.82 3 ! 26.4 0.0 5.3e-07 4.3e-05 9 38 .] 94 124 .. 88 124 .. 0.91 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 0.00071 SEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 12 svtslafspdgaw.lasGsdDgtvriWd 38 +++s++fsp+ + l+ +s+D +vr++d tr|J3QSX4|J3QSX4_HUMAN 16 GISSVKFSPNTSQfLLVSSWDTSVRLYD 43 499**********54589********98 PP == domain 2 score: 8.8 bits; conditional E-value: 0.19 SS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla.fspdgawlasGsdDgtvriW 37 H + v ++a ++p +aw sG+ D+ +++ tr|J3QSX4|J3QSX4_HUMAN 54 QHtGAVLDCAfYDPTHAW--SGGLDHQLKMH 82 47555988888*******..8*******985 PP == domain 3 score: 26.4 bits; conditional E-value: 5.3e-07 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++++ ++p+ + +++Gs+D+tv++Wd tr|J3QSX4|J3QSX4_HUMAN 94 THdAPIRCVEYCPEVNVMVTGSWDQTVKLWD 124 68777*************************9 PP >> sp|Q9C0J8-3|WDR33_HUMAN Isoform 3 of pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens GN=WDR33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 3.9 3.2e+02 13 38 .] 122 147 .. 108 147 .. 0.81 2 ! 14.8 0.1 0.0024 0.19 5 37 .. 155 188 .. 151 189 .. 0.90 3 ! 31.4 0.0 1.4e-08 1.1e-06 2 38 .] 193 230 .. 192 230 .. 0.92 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 3.9 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v +++ p+g+ l++G g +W+ sp|Q9C0J8-3|WDR33_HUMAN 122 VFVVRWTPEGRRLVTGASSGEFTLWN 147 55578***********5599999997 PP == domain 2 score: 14.8 bits; conditional E-value: 0.0024 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l +H s+v+++ +s++ w+++++ g v+ W sp|Q9C0J8-3|WDR33_HUMAN 155 TILQAHdSPVRAMTWSHNDMWMLTADHGGYVKYW 188 5789**888****************88*****99 PP == domain 3 score: 31.4 bits; conditional E-value: 1.4e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ + +H ++ +fsp + +a++sdDgtvriWd sp|Q9C0J8-3|WDR33_HUMAN 193 NNVKMFQAHkEAIREASFSPTDNKFATCSDDGTVRIWD 230 68899****655*************************9 PP >> sp|Q9ULV4-3|COR1C_HUMAN Isoform 3 of Coronin-1C OS=Homo sapiens GN=CORO1C # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.6 2.4e-06 0.00019 7 37 .. 129 161 .. 122 162 .. 0.86 2 ! 15.2 0.1 0.0018 0.14 3 38 .] 175 212 .. 173 212 .. 0.83 3 ! 15.5 0.2 0.0015 0.12 10 38 .] 226 255 .. 220 255 .. 0.92 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 2.4e-06 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W sp|Q9ULV4-3|COR1C_HUMAN 129 VCGHtGPVLDIDWCPHNDQViASGSEDCTVMVW 161 459*888************73699********* PP == domain 2 score: 15.2 bits; conditional E-value: 0.0018 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ + iW+ sp|Q9ULV4-3|COR1C_HUMAN 175 PVVILEGHsKRVGIVAWHPTARNVLlsAGC-DNAIIIWN 212 67899***888*9999*******6332677.*******8 PP == domain 3 score: 15.5 bits; conditional E-value: 0.0015 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 Hs+ ++ ++++++g++++++s+D++vr+ d sp|Q9ULV4-3|COR1C_HUMAN 226 HSDmIYNVSWNRNGSLICTASKDKKVRVID 255 86789**********************965 PP >> tr|C9JRL6|C9JRL6_HUMAN Echinoderm microtubule-associated protein-like 2 OS=Homo sapiens GN=EML2 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.1 0.001 0.085 2 38 .] 254 301 .. 253 301 .. 0.81 2 ? 3.5 0.2 9.1 7.4e+02 13 38 .] 320 349 .. 307 349 .. 0.69 3 ? 3.8 0.0 7.2 5.8e+02 18 37 .. 371 390 .. 354 391 .. 0.74 4 ? 5.8 0.0 1.7 1.4e+02 7 37 .. 404 436 .. 398 436 .. 0.82 5 ! 14.6 0.1 0.0029 0.23 4 37 .. 445 479 .. 442 479 .. 0.89 6 ! 14.6 0.2 0.0029 0.23 8 38 .] 532 563 .. 522 563 .. 0.89 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 0.001 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 q +r++ GH +++ +la +pd +a+G + ++vriWd tr|C9JRL6|C9JRL6_HUMAN 254 QRQRHYLGHnDDIKCLAIHPDMVTIATGqvaGTtkegkplPPHVRIWD 301 779******666*************99754422457778899999998 PP == domain 2 score: 3.5 bits; conditional E-value: 9.1 EEEEE..EETTSSEEEEE..ETTSEEEEEE CS WD40 13 vtsla..fspdgawlasG..sdDgtvriWd 38 v+++ s g++l++ s D+ + +Wd tr|C9JRL6|C9JRL6_HUMAN 320 VCCVGfsKSNGGNLLCAVdeSNDHMLSVWD 349 5555443566666775445556*******9 PP == domain 3 score: 3.8 bits; conditional E-value: 7.2 EETTSSE.EEEEETTSEEEEE CS WD40 18 fspdgaw.lasGsdDgtvriW 37 f+p + l++++ + ++++W tr|C9JRL6|C9JRL6_HUMAN 371 FHPTDPTvLITCG-KSHIYFW 390 77777783569**.******* PP == domain 4 score: 5.8 bits; conditional E-value: 1.7 EESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ss..vtslafspdgawlasGsdDgtvriW 37 ++ H ++ v ++ f g+ + +G+ g++++W tr|C9JRL6|C9JRL6_HUMAN 404 FEKHeKPkyVLCVTFLEGGDVV-TGDSGGNLYVW 436 677987788****999999996.7*66******9 PP == domain 5 score: 14.6 bits; conditional E-value: 0.0029 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l +H ++v +l+ +dg++++ G++D+ v +W tr|C9JRL6|C9JRL6_HUMAN 445 QAVLGAHdGGVFGLCALRDGTLVSGGGRDRRVVLW 479 67899**777************97668******** PP == domain 6 score: 14.6 bits; conditional E-value: 0.0029 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++la++p+ a +++++ D+ v++W+ tr|C9JRL6|C9JRL6_HUMAN 532 QGHvEELWGLATHPSRAQFVTCGQDKLVHLWS 563 5998889************************5 PP >> tr|J3KRG6|J3KRG6_HUMAN WD repeat and SOCS box-containing protein 1 OS=Homo sapiens GN=WSB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.4 0.0 6e-08 4.8e-06 2 38 .] 15 53 .. 14 53 .. 0.84 2 ! 23.1 0.0 5.9e-06 0.00048 2 28 .. 59 86 .. 58 93 .. 0.84 Alignments for each domain: == domain 1 score: 29.4 bits; conditional E-value: 6e-08 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 ++l l H+ v++l f pdg+++ +s+s+D+t+r+Wd tr|J3KRG6|J3KRG6_HUMAN 15 KLLLNLVDHTEvVRDLTFAPDGSLIlVSASRDKTLRVWD 53 6677788896657***********62589*********9 PP == domain 2 score: 23.1 bits; conditional E-value: 5.9e-06 EEEEEEESS.SSEEEEEEETTSSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG 28 + +++l+GH ++v+s+afspd+++l+s tr|J3KRG6|J3KRG6_HUMAN 59 NMMKVLRGHqNWVYSCAFSPDSSMLCSV 86 67899****999************9864 PP >> sp|Q92466-4|DDB2_HUMAN Isoform D3 of DNA damage-binding protein 2 OS=Homo sapiens GN=DDB2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.2 3.8e-07 3.1e-05 2 38 .] 169 207 .. 168 207 .. 0.89 2 ? 11.9 0.0 0.02 1.6 10 37 .. 223 251 .. 216 252 .. 0.84 3 ? 7.2 0.0 0.61 50 12 38 .] 329 355 .. 307 355 .. 0.85 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 3.8e-07 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + l+ l+ H + vt++a +p +w la++s D+tv+iWd sp|Q92466-4|DDB2_HUMAN 169 KELWNLRMHkKKVTHVALNPCCDWfLATASVDQTVKIWD 207 67888999*888************55799*********9 PP == domain 2 score: 11.9 bits; conditional E-value: 0.02 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H +v++ +fspdga l++ + + +r++ sp|Q92466-4|DDB2_HUMAN 223 HrHPVNAACFSPDGARLLTTDQKSEIRVY 251 5448**************99999999997 PP == domain 3 score: 7.2 bits; conditional E-value: 0.61 SEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 12 svtsla.fspdgawlasGsdDgtvriWd 38 +++sl f+p g+ las++ ++ iW+ sp|Q92466-4|DDB2_HUMAN 329 GISSLNeFNPMGDTLASAM-GYHILIWS 355 4888889********9988.*******5 PP >> sp|Q96EX3|WDR34_HUMAN WD repeat-containing protein 34 OS=Homo sapiens GN=WDR34 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.2 2.6 2.1e+02 12 28 .. 161 179 .. 146 190 .. 0.71 2 ? 10.6 0.0 0.052 4.2 12 38 .] 219 246 .. 208 246 .. 0.87 3 ? 3.7 0.1 7.8 6.3e+02 9 37 .. 264 298 .. 257 299 .. 0.67 4 ! 13.8 0.1 0.0049 0.4 5 37 .. 386 420 .. 384 421 .. 0.79 5 ! 13.8 0.0 0.0052 0.42 11 37 .. 483 510 .. 472 511 .. 0.75 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 2.6 S..EEEEEEETTSSEEEEE CS WD40 12 s..vtslafspdgawlasG 28 + vts+++++ g+ +a++ sp|Q96EX3|WDR34_HUMAN 161 GlhVTSISWNSTGSVVACA 179 244************9865 PP == domain 2 score: 10.6 bits; conditional E-value: 0.052 SEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 12 svtslafspdgawlasGs.dDgtvriWd 38 v +laf+p ++ +++G+ + g v +Wd sp|Q96EX3|WDR34_HUMAN 219 AVLCLAFHPTQPSHVAGGlYSGEVLVWD 246 599**************867*******9 PP == domain 3 score: 3.7 bits; conditional E-value: 7.8 SS.SSEEEEEEETTSSE......EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw......lasGsdDgtvriW 37 +H ++v+ + + p+ l+ ++ Dg+v +W sp|Q96EX3|WDR34_HUMAN 264 THtDPVSQVVWLPEPGHshrfqvLSVAT-DGKVLLW 298 5756677775444444466777455566.******* PP == domain 4 score: 13.8 bits; conditional E-value: 0.0049 EEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawla.sGsdDgtvriW 37 t++ H ++++s++ sp ++ l+ s++ Dg+v+++ sp|Q96EX3|WDR34_HUMAN 386 FTFSPHgGPIYSVSCSPFHRNLFlSAGTDGHVHLY 420 68999*888*****89888886335555*****98 PP == domain 5 score: 13.8 bits; conditional E-value: 0.0052 SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 11 ssvtslafspdgaw.lasGsdDgtvriW 37 s+v++l f++ ++ la+G+ gtv++W sp|Q96EX3|WDR34_HUMAN 483 SPVYCLEFNSQQTQlLAAGDAQGTVKVW 510 569****66666662567878******* PP >> tr|F6UT28|F6UT28_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Fragment) OS=Homo sapiens G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.0 6.2e-07 5e-05 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 14.8 0.1 0.0024 0.2 12 38 .] 99 125 .. 86 125 .. 0.85 3 ? 11.5 0.1 0.027 2.2 5 33 .. 137 165 .] 133 165 .] 0.85 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 6.2e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd tr|F6UT28|F6UT28_HUMAN 48 RRTLRGHlAKIYAMHWGTDSRLLVSASQDGKLIIWD 83 689****999*************************9 PP == domain 2 score: 14.8 bits; conditional E-value: 0.0024 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v +a+ p+g+++a+G+ D+ + i++ tr|F6UT28|F6UT28_HUMAN 99 WVMTCAYAPSGNYVACGGLDNICSIYN 125 488889*******************97 PP == domain 3 score: 11.5 bits; conditional E-value: 0.027 EEEESS.SSEEEEEEETTSSEEEEEETTSE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgt 33 r+l GH + ++++f +d++ ++s++ D t tr|F6UT28|F6UT28_HUMAN 137 RELAGHtGYLSCCRFLDDNQIVTSSG-DTT 165 7899**666************99888.876 PP >> tr|K7EJR7|K7EJR7_HUMAN Transducin-like enhancer protein 2 (Fragment) OS=Homo sapiens GN=TLE2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.3 0.00021 0.017 3 38 .] 99 133 .. 97 133 .. 0.89 2 ? 8.3 0.0 0.28 23 12 38 .] 154 180 .. 143 180 .. 0.91 3 ! 15.6 0.2 0.0013 0.11 14 38 .] 200 224 .. 190 224 .. 0.85 4 ! 17.4 0.6 0.00038 0.031 4 38 .] 231 266 .. 228 266 .. 0.89 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 0.00021 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +l+tl +H+ v+++ s + + + +G+ +g v++Wd tr|K7EJR7|K7EJR7_HUMAN 99 QLHTL-AHGEvVCAVTISGSTQHVYTGG-KGCVKVWD 133 68888.8*6657****************.*******9 PP == domain 2 score: 8.3 bits; conditional E-value: 0.28 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++ pdg+ l+ G++ t+ iWd tr|K7EJR7|K7EJR7_HUMAN 154 YIRSCKLLPDGRSLIVGGEASTLSIWD 180 499999********************9 PP == domain 3 score: 15.6 bits; conditional E-value: 0.0013 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++la+spd + +s++ Dg++ +Wd tr|K7EJR7|K7EJR7_HUMAN 200 YALAVSPDAKVCFSCCSDGNIVVWD 224 6899*******887755*******9 PP == domain 4 score: 17.4 bits; conditional E-value: 0.00038 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r + GH ++ ++++ s++g+ l +G+ D+tvr Wd tr|K7EJR7|K7EJR7_HUMAN 231 VRQFQGHtDGASCIDISDYGTRLWTGGLDNTVRCWD 266 7889***7779***********747999*******9 PP >> sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.033 2.7 13 36 .. 2276 2302 .. 2261 2302 .. 0.74 2 ! 23.1 0.3 5.7e-06 0.00046 1 37 [. 2308 2345 .. 2308 2346 .. 0.90 3 ! 17.7 0.0 0.00031 0.025 2 36 .. 2360 2395 .. 2359 2396 .. 0.92 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.033 E..EEEEEETTSSEEEEE.ETTSEEEE CS WD40 13 v..tslafspdgawlasG.sdDgtvri 36 v +la+ pdg++l+sG ++Dg++r+ sp|Q6ZNJ1-2|NBEL2_HUMAN 2276 VsgQALAVAPDGKLLFSGgHWDGSLRV 2302 6333566**********9569****97 PP == domain 2 score: 23.1 bits; conditional E-value: 5.7e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g++l l+ H + vt+la + g +l+sGs+D t+++W sp|Q6ZNJ1-2|NBEL2_HUMAN 2308 GKLLSQLSCHlDVVTCLALDTCGIYLISGSRDTTCMVW 2345 5788899***5558************************ PP == domain 3 score: 17.7 bits; conditional E-value: 0.00031 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++++l GH v+++a s + ++ +sGs+Dgtv i sp|Q6ZNJ1-2|NBEL2_HUMAN 2360 KPVQVLYGHgAAVSCVAISTELDMAVSGSEDGTVII 2395 68999****766*********************976 PP >> tr|F5H5D4|F5H5D4_HUMAN Proteasomal ATPase-associated factor 1 (Fragment) OS=Homo sapiens GN=PAAF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.1 8.2e-05 0.0066 9 37 .. 68 97 .. 59 98 .. 0.81 2 ! 31.8 0.0 1e-08 8.2e-07 2 38 .] 103 140 .. 102 140 .. 0.94 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 8.2e-05 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 H +s+t+l+ s+ g + ++ +s Dgt +iW tr|F5H5D4|F5H5D4_HUMAN 68 IHtKSITCLDISSRGGLgVS-SSTDGTMKIW 97 69999*****9999999565.566******* PP == domain 2 score: 31.8 bits; conditional E-value: 1e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+l+GH ++v++++f p+g ++sG++D ++iW+ tr|F5H5D4|F5H5D4_HUMAN 103 ELRRVLEGHvFDVNCCRFFPSGLVVLSGGMDAQLKIWS 140 67799****999*************************5 PP >> tr|Q9NSS8|Q9NSS8_HUMAN Putative uncharacterized protein DKFZp434D199 OS=Homo sapiens GN=DKFZp434D199 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 0.1 2.7e-07 2.2e-05 2 38 .] 42 83 .. 41 83 .. 0.85 2 ! 22.3 0.0 1.1e-05 0.00086 3 34 .. 89 121 .. 87 123 .. 0.87 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 2.7e-07 EEEEEEESS..SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH..ss...vtslafspdgawlasGsdDgtvriWd 38 +c++++ G ++ +++spdg+ +a+Gs D+ v++Wd tr|Q9NSS8|Q9NSS8_HUMAN 42 RCVKIFQGNvhNFeknLLRCSWSPDGSKIAAGSADRFVYVWD 83 799999988544466777888********************9 PP == domain 2 score: 22.3 bits; conditional E-value: 1.1e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtv 34 l++l GH +s++ +af+pd + ++s+s D+ + tr|Q9NSS8|Q9NSS8_HUMAN 89 ILYKLPGHaGSINEVAFHPDEPIIISASSDKRL 121 578899**999*************999779987 PP >> sp|Q5QP82-2|DCA10_HUMAN Isoform 2 of DDB1- and CUL4-associated factor 10 OS=Homo sapiens GN=DCAF10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 2.8 2.2e+02 8 38 .] 166 196 .. 160 196 .. 0.80 2 ! 16.6 0.1 0.00067 0.054 3 38 .] 202 238 .. 200 238 .. 0.79 3 ! 20.6 0.8 3.6e-05 0.0029 4 38 .] 246 281 .. 243 281 .. 0.90 4 ? 5.3 0.0 2.5 2e+02 13 27 .. 438 452 .. 422 468 .. 0.74 5 ? 6.0 0.1 1.5 1.2e+02 4 37 .. 484 518 .. 481 519 .. 0.84 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 2.8 ESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriWd 38 ++H+ v l +spdg+ l+ +++ v ++d sp|Q5QP82-2|DCA10_HUMAN 166 RTHGAVFNLEYSPDGSVLTVACEQTEVLLFD 196 68978************98777677777665 PP == domain 2 score: 16.6 bits; conditional E-value: 0.00067 EEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 +++tl+ +H ++v+ ++f ++ + a++sdD t+ +Wd sp|Q5QP82-2|DCA10_HUMAN 202 HIKTLSeAHeDCVNNIRFLDNRLF-ATCSDDTTIALWD 238 567776699777888877777666.89**********9 PP == domain 3 score: 20.6 bits; conditional E-value: 3.6e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + tl GH s+v + ++ + ++l++++ Dg+v iWd sp|Q5QP82-2|DCA10_HUMAN 246 VCTLHGHtSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281 67899**888*************98888*******9 PP == domain 4 score: 5.3 bits; conditional E-value: 2.5 EEEEEEETTSSEEEE CS WD40 13 vtslafspdgawlas 27 + l+fspdg++++s sp|Q5QP82-2|DCA10_HUMAN 438 IKELCFSPDGRMISS 452 8889********876 PP == domain 5 score: 6.0 bits; conditional E-value: 1.5 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +r+l H++ v +fsp + +asG+ g v ++ sp|Q5QP82-2|DCA10_HUMAN 484 IRSLYSHNDvVLTTKFSPTHCQIASGCLSGRVSLY 518 788999*99569999***********988888775 PP >> sp|Q96EE3-1|SEH1_HUMAN Isoform B of Nucleoporin SEH1 OS=Homo sapiens GN=SEH1L # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.9 2.1e-05 0.0017 10 38 .] 11 40 .. 5 40 .. 0.92 2 ? 11.3 2.6 0.032 2.6 2 37 .. 48 86 .. 47 87 .. 0.85 3 ? 11.2 0.0 0.034 2.7 11 37 .. 114 142 .. 97 143 .. 0.76 4 ? 3.7 0.6 7.8 6.3e+02 13 32 .. 165 189 .. 152 190 .. 0.75 5 ! 22.2 1.9 1.2e-05 0.00094 6 38 .] 273 306 .. 268 306 .. 0.87 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 2.1e-05 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H++ +++++f+ +g+ +a++s D++v++Wd sp|Q96EE3-1|SEH1_HUMAN 11 HKDlIHDVSFDFHGRRMATCSSDQSVKVWD 40 87789***************88*******9 PP == domain 2 score: 11.3 bits; conditional E-value: 0.032 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriW 37 c+ ++++H +sv+ + +w las+s D+t +W sp|Q96EE3-1|SEH1_HUMAN 48 HCTASWKTHsGSVWRV------TWahpefgqvLASCSFDRTAAVW 86 79999****777****......777777777799********999 PP == domain 3 score: 11.2 bits; conditional E-value: 0.034 SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 11 ssvtslafspdgaw..lasGsdDgtvriW 37 +svt+++f p + la++s Dg vri+ sp|Q96EE3-1|SEH1_HUMAN 114 TSVTDVKFAPKHMGlmLATCSADGIVRIY 142 459999766665555579**********8 PP == domain 4 score: 3.7 bits; conditional E-value: 7.8 EEEEEEETTSSE.....EEEEETTS CS WD40 13 vtslafspdgaw.....lasGsdDg 32 ++++++p+++ +a GsdD sp|Q96EE3-1|SEH1_HUMAN 165 CSCISWNPSSSRahspmIAVGSDDS 189 5799999999999999888999885 PP == domain 5 score: 22.2 bits; conditional E-value: 1.2e-05 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ H s v+ ++++ g+ las++dDg vr+W+ sp|Q96EE3-1|SEH1_HUMAN 273 QFDNHnSQVWRVSWNITGTVLASSGDDGCVRLWK 306 57889555**************999********6 PP >> sp|Q8NHV4|NEDD1_HUMAN Protein NEDD1 OS=Homo sapiens GN=NEDD1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.5 0.0051 0.42 8 34 .. 29 60 .. 23 61 .. 0.71 2 ? 10.5 0.0 0.056 4.5 14 38 .] 81 105 .. 74 105 .. 0.93 3 ? 11.0 0.2 0.04 3.2 5 32 .. 113 141 .. 109 147 .. 0.83 4 ? 7.2 0.2 0.64 51 8 38 .] 157 191 .. 148 191 .. 0.77 5 ? 7.9 0.0 0.37 30 3 38 .] 241 276 .. 239 276 .. 0.79 6 ? 5.2 0.1 2.6 2.1e+02 2 20 .. 282 301 .. 281 317 .. 0.84 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.0051 ESS.SS..EEEEEEETTSSEEEEE..ETTSEE CS WD40 8 tGH.ss..vtslafspdgawlasG..sdDgtv 34 H s+ ++s+++s+++++l+++ s D+ v sp|Q8NHV4|NEDD1_HUMAN 29 NPHtSPhgISSICWSSNNNFLVTAssSGDKIV 60 55654466*************86522348776 PP == domain 2 score: 10.5 bits; conditional E-value: 0.056 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 t++ ++ + +l+sG+ ++tv iWd sp|Q8NHV4|NEDD1_HUMAN 81 TCVNLNSTSMYLVSGGLNNTVNIWD 105 79999999999*************9 PP == domain 3 score: 11.0 bits; conditional E-value: 0.04 EEEESSSS.EEEEEEETTSSEEEEEETTS CS WD40 5 rtltGHss.vtslafspdgawlasGsdDg 32 r+l+ H++ vt++ ++ + ++asGs g sp|Q8NHV4|NEDD1_HUMAN 113 RSLKDHKDqVTCVTYNWNDCYIASGSLSG 141 68999*555******99********9655 PP == domain 4 score: 7.2 bits; conditional E-value: 0.64 ESS.SS..EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 8 tGH.ss..vtslafspdgawlasG..sdDgtvriWd 38 GH s+ v++l++s ++ l+ G sd+g v +Wd sp|Q8NHV4|NEDD1_HUMAN 157 FGHgSNqsVRHLKYSLFKKSLL-GsvSDNGIVTLWD 191 39973367****9998899999.53579*******9 PP == domain 5 score: 7.9 bits; conditional E-value: 0.37 EEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtvriWd 38 +++tl + ++ t+++f pdga la Gs g+++ +d sp|Q8NHV4|NEDD1_HUMAN 241 LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYD 276 56777666779***************8677776665 PP == domain 6 score: 5.2 bits; conditional E-value: 2.6 EEEEEEESS.SSEEEEEEET CS WD40 2 qclrtltGH.ssvtslafsp 20 ++++t+++H +sv ++af+ sp|Q8NHV4|NEDD1_HUMAN 282 SPVKTISAHkTSVQCIAFQY 301 6899*****888****8764 PP >> sp|Q9BR76|COR1B_HUMAN Coronin-1B OS=Homo sapiens GN=CORO1B PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.2 4.9e-06 0.0004 8 37 .. 79 110 .. 73 111 .. 0.86 2 ! 15.8 0.0 0.0012 0.096 3 38 .] 124 161 .. 122 161 .. 0.84 3 ! 14.5 0.4 0.0031 0.25 10 38 .] 175 204 .. 170 204 .. 0.87 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 4.9e-06 ESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W sp|Q9BR76|COR1B_HUMAN 79 CGHtGPVLDIDWCPHNDEViASGSEDCTVMVW 110 59*888************73699********* PP == domain 2 score: 15.8 bits; conditional E-value: 0.0012 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ v iW+ sp|Q9BR76|COR1B_HUMAN 124 PVVVLEGHtKRVGIIAWHPTARNVLlsAGC-DNVVLIWN 161 67899***999*9999*******6342677.*******8 PP == domain 3 score: 14.5 bits; conditional E-value: 0.0031 SSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriWd 38 H + ++ ++++++g++++s+++D++vri d sp|Q9BR76|COR1B_HUMAN 175 H-PdlIYNVSWNHNGSLFCSACKDKSVRIID 204 5.235999********************966 PP >> sp|Q8TDJ6-2|DMXL2_HUMAN Isoform 2 of DmX-like protein 2 OS=Homo sapiens GN=DMXL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.8 0.016 1.3 9 37 .. 168 197 .. 160 197 .. 0.71 2 ? 10.6 0.2 0.053 4.3 6 37 .. 227 268 .. 222 268 .. 0.79 3 ? 4.7 0.6 3.9 3.1e+02 8 38 .] 2213 2247 .. 2207 2247 .. 0.72 4 ? 9.7 0.1 0.1 8.3 3 38 .] 2256 2292 .. 2254 2292 .. 0.85 5 ! 21.5 0.0 1.9e-05 0.0016 2 37 .. 2297 2333 .. 2296 2334 .. 0.94 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.016 SSSSEEEEE.....EETTSSEEEEEE.TTSEEEEE CS WD40 9 GHssvtsla.....fspdgawlasGs.dDgtvriW 37 + ++ +spdg ++a+++ dD+ +++W sp|Q8TDJ6-2|DMXL2_HUMAN 168 TS-----VSvhlmeWSPDGEYFATAGkDDCLLKVW 197 33.....2344667*********88757******* PP == domain 2 score: 10.6 bits; conditional E-value: 0.053 EEESS.SSEEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgaw..........lasGsdDgtvriW 37 ++ +H vt++++ + +++ l+s++ Dg +r+W sp|Q8TDJ6-2|DMXL2_HUMAN 227 VYLAHpRAVTGFSWRKTSKYmprgsvcnvlLTSCH-DGVCRLW 268 56689555999998888888999999998566777.******* PP == domain 3 score: 4.7 bits; conditional E-value: 3.9 ESS.SSEEEEEEETTSSEEEEEE...TTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGs...dDgtvriWd 38 H + +++af +++++a+++ d+++v +Wd sp|Q8TDJ6-2|DMXL2_HUMAN 2213 QCHsKATSDFAFITSSSLVATSGhsnDNRNVCLWD 2247 567444467778888899996543678*******9 PP == domain 4 score: 9.7 bits; conditional E-value: 0.1 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++ +t H++ t l++ p +++l+sG+++g+v i+d sp|Q8TDJ6-2|DMXL2_HUMAN 2256 LIHGFTCHDHgATVLQYAPKQQLLISGGRKGHVCIFD 2292 57778999445888899******************98 PP == domain 5 score: 21.5 bits; conditional E-value: 1.9e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 q+++t+ +H s + +la +p+ ++++Gs g++++W sp|Q8TDJ6-2|DMXL2_HUMAN 2297 QLIHTFQAHdSAIKALALDPYEEYFTTGSAEGNIKVW 2333 899******777************************* PP >> sp|Q5QP82|DCA10_HUMAN DDB1- and CUL4-associated factor 10 OS=Homo sapiens GN=DCAF10 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 3 2.4e+02 8 38 .] 166 196 .. 160 196 .. 0.80 2 ! 16.5 0.1 0.00073 0.059 3 38 .] 202 238 .. 200 238 .. 0.79 3 ! 20.5 0.8 4e-05 0.0032 4 38 .] 246 281 .. 243 281 .. 0.90 4 ? 5.2 0.0 2.7 2.2e+02 13 27 .. 475 489 .. 459 505 .. 0.74 5 ? 5.8 0.1 1.7 1.3e+02 4 37 .. 521 555 .. 518 556 .. 0.84 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 3 ESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriWd 38 ++H+ v l +spdg+ l+ +++ v ++d sp|Q5QP82|DCA10_HUMAN 166 RTHGAVFNLEYSPDGSVLTVACEQTEVLLFD 196 68978************98777677777665 PP == domain 2 score: 16.5 bits; conditional E-value: 0.00073 EEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 +++tl+ +H ++v+ ++f ++ + a++sdD t+ +Wd sp|Q5QP82|DCA10_HUMAN 202 HIKTLSeAHeDCVNNIRFLDNRLF-ATCSDDTTIALWD 238 567776699777888877777666.89**********9 PP == domain 3 score: 20.5 bits; conditional E-value: 4e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + tl GH s+v + ++ + ++l++++ Dg+v iWd sp|Q5QP82|DCA10_HUMAN 246 VCTLHGHtSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281 67899**888*************98888*******9 PP == domain 4 score: 5.2 bits; conditional E-value: 2.7 EEEEEEETTSSEEEE CS WD40 13 vtslafspdgawlas 27 + l+fspdg++++s sp|Q5QP82|DCA10_HUMAN 475 IKELCFSPDGRMISS 489 8889********876 PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +r+l H++ v +fsp + +asG+ g v ++ sp|Q5QP82|DCA10_HUMAN 521 IRSLYSHNDvVLTTKFSPTHCQIASGCLSGRVSLY 555 788999*99569999***********988888775 PP >> tr|Q8TBB7|Q8TBB7_HUMAN DDB1- and CUL4-associated factor 5 OS=Homo sapiens GN=WDR22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.1 1.3e-05 0.0011 7 37 .. 49 81 .. 42 82 .. 0.86 2 ? 10.0 0.0 0.083 6.7 9 35 .. 100 126 .. 92 129 .. 0.81 3 ! 19.4 0.1 8.3e-05 0.0067 7 38 .] 139 171 .. 133 171 .. 0.81 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.3e-05 EESS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.fspdgawlasGsdDgtvriW 37 l GH ++v+++ + g+wl+sG+dD+ v +W tr|Q8TBB7|Q8TBB7_HUMAN 49 LLGHfGCVNAIEfSNNGGQWLVSGGDDRRVLLW 81 569*777*****88888888************* PP == domain 2 score: 10.0 bits; conditional E-value: 0.083 SSSSEEEEEEETTSSEEEEEETTSEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvr 35 Hs++ +laf++ ++ ++sG+ D v tr|Q8TBB7|Q8TBB7_HUMAN 100 HHSNIFCLAFNSGNTKVFSGGNDEQVI 126 4588****************9887765 PP == domain 3 score: 19.4 bits; conditional E-value: 8.3e-05 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + +H + v++l++sp ++ + as+sdDg v iWd tr|Q8TBB7|Q8TBB7_HUMAN 139 F-AHeDAVYGLSVSPVNDNIfASSSDDGRVLIWD 171 4.79777*****9999999735779********9 PP >> tr|D6R9Q1|D6R9Q1_HUMAN Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (Fragment) OS=Homo sapiens # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.5 0.0061 0.49 13 38 .] 12 36 .. 4 36 .. 0.75 2 ! 15.8 0.0 0.0012 0.096 3 38 .] 44 80 .. 42 80 .. 0.89 3 ! 17.8 0.0 0.00027 0.022 14 37 .. 203 226 .. 195 227 .. 0.90 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.0061 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 +t++ ++ ++++++s Dg+v++W+ tr|D6R9Q1|D6R9Q1_HUMAN 12 ITHV-VCTKTDFIITASHDGHVKFWK 36 4555.5556788999999*******6 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0012 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++ H + + s+a+s++ga+++s +dD+ +++d tr|D6R9Q1|D6R9Q1_HUMAN 44 FVKHFRSHlGVIESIAVSSEGALFCSVGDDKAMKVFD 80 5899****6668************98899****9998 PP == domain 3 score: 17.8 bits; conditional E-value: 0.00027 EEEEEETTSSEEEE.EETTSEEEEE CS WD40 14 tslafspdgawlas.GsdDgtvriW 37 ts++fspdg+ +a+ Gs D++vri+ tr|D6R9Q1|D6R9Q1_HUMAN 203 TSVCFSPDGKKIATiGS-DRKVRIF 226 89**********95499.*****97 PP >> sp|Q562E7-2|WDR81_HUMAN Isoform 2 of WD repeat-containing protein 81 OS=Homo sapiens GN=WDR81 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.0 2e-07 1.6e-05 4 37 .. 392 426 .. 390 426 .. 0.92 2 ? 6.3 0.0 1.2 96 6 38 .] 443 474 .. 439 474 .. 0.68 3 ? 3.9 0.0 6.6 5.3e+02 9 29 .. 533 556 .. 524 563 .. 0.75 4 ? 7.7 0.2 0.42 34 7 38 .] 575 606 .. 569 606 .. 0.75 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 2e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l+++ GH + v ++a ++ ++++sGs+D+tvr+W sp|Q562E7-2|WDR81_HUMAN 392 LQSFPGHsGAVKCVAPLSSEDFFLSGSKDRTVRLW 426 6899***555************************* PP == domain 2 score: 6.3 bits; conditional E-value: 1.2 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 ++t H +sv + g++ ++ ++ Dg v++Wd sp|Q562E7-2|WDR81_HUMAN 443 VYTQHrKSVFFV-----GQLeapqHVVSC-DGAVHVWD 474 677888886555.....444444455578.*******9 PP == domain 3 score: 3.9 bits; conditional E-value: 6.6 SS.SS..EEEEEEETTSSEEEEEE CS WD40 9 GH.ss..vtslafspdgawlasGs 29 G ++ v++la sp+g+ +++G sp|Q562E7-2|WDR81_HUMAN 533 GGlNPglVRALAISPSGRSVVAGF 556 44556779************9993 PP == domain 4 score: 7.7 bits; conditional E-value: 0.42 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 + +H ++ + ++ +g+ l+s+s D+++ +W+ sp|Q562E7-2|WDR81_HUMAN 575 WPAHeGDilqIKAV----EGSVLVSSSSDHSLTVWK 606 56786666666777....7888998877*******6 PP >> sp|Q9Y485|DMXL1_HUMAN DmX-like protein 1 OS=Homo sapiens GN=DMXL1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.5 0.004 0.32 1 37 [. 159 196 .. 159 196 .. 0.87 2 ? 8.2 0.1 0.29 24 7 37 .. 227 267 .. 222 268 .. 0.81 3 ? 4.3 0.2 4.9 4e+02 6 38 .] 2833 2869 .. 2828 2869 .. 0.76 4 ? 5.2 0.1 2.7 2.2e+02 3 38 .] 2878 2914 .. 2876 2914 .. 0.86 5 ! 17.7 0.0 0.0003 0.024 6 38 .] 2923 2956 .. 2917 2956 .. 0.88 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.004 TEEEEEEESSSSEEEEEEETTSSEEEEEE.TTSEEEEE CS WD40 1 gqclrtltGHssvtslafspdgawlasGs.dDgtvriW 37 ++c++++++ s v+ ++fspdg ++a+++ dD+ +++W sp|Q9Y485|DMXL1_HUMAN 159 WKCIWHCKTASQVHLMKFSPDGEFFATAGkDDCLLKVW 196 68889988887798889*********88757******* PP == domain 2 score: 8.2 bits; conditional E-value: 0.29 EESS.SSEEEEEEETTSSE.........EEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgaw.........lasGsdDgtvriW 37 + +H v+++++ + +++ l+++++D+ +r+W sp|Q9Y485|DMXL1_HUMAN 227 YLAHpRAVNGFSWRKTSKYmprasvcnvLLTCCKDNVCRLW 267 5578555999988888888888888888889********** PP == domain 3 score: 4.3 bits; conditional E-value: 4.9 EEESS.SSEEEEEEETTSSEEEEEE...TTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGs...dDgtvriWd 38 t+ H + +++ f ++++++a+++ d+++v +Wd sp|Q9Y485|DMXL1_HUMAN 2833 TWQCHnKTANDFVFVSSSSLIATAGlstDNRNVCLWD 2869 56678666788888899999997643459*******9 PP == domain 4 score: 5.2 bits; conditional E-value: 2.7 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +t H s+ t la+ p +++l+sG+++g +++d sp|Q9Y485|DMXL1_HUMAN 2878 LVHAFTCHdSGATVLAYAPKHQLLISGGRKGFTYVFD 2914 7899****888999999***********998766665 PP == domain 5 score: 17.7 bits; conditional E-value: 0.0003 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H s+v ++a++p ++++Gs g+++iW+ sp|Q9Y485|DMXL1_HUMAN 2923 LFQSHdSPVKAVAVDPTEEYFVTGSAEGNIKIWS 2956 4789*888*************************5 PP >> sp|Q64LD2|WDR25_HUMAN WD repeat-containing protein 25 OS=Homo sapiens GN=WDR25 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.1 3.4e-05 0.0027 2 38 .] 237 277 .. 236 277 .. 0.80 2 ? 9.6 0.1 0.1 8.4 1 35 [. 282 317 .. 282 320 .. 0.87 3 ! 14.5 0.0 0.0029 0.24 5 37 .. 465 500 .. 462 501 .. 0.79 4 ? 5.7 0.3 1.8 1.5e+02 6 37 .. 510 543 .. 507 544 .] 0.67 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 3.4e-05 EEEEEEESS.SSEEEEEEETTSSE.........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.........lasGsdDgtvriWd 38 + l +l+GH ++v+ + +w l+s s+D+t ++W+ sp|Q64LD2|WDR25_HUMAN 237 KVLFHLRGHrGPVNTI------QWcpvlskshmLLSTSMDKTFKVWN 277 6789*****999****......66666666766667777*******8 PP == domain 2 score: 9.6 bits; conditional E-value: 0.1 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvr 35 g cl+t++ H v++ ++ p g+ ++sG+ D ++ sp|Q64LD2|WDR25_HUMAN 282 GHCLQTYSLHtEAVRAARWAPCGRRILSGGFDFALH 317 579*******777****************9887665 PP == domain 3 score: 14.5 bits; conditional E-value: 0.0029 EEEESS..SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH..ss..vtslafspdgawlasGsdDgtvriW 37 r ++GH + v ++ sp g++l++Gs Dg v ++ sp|Q64LD2|WDR25_HUMAN 465 RRYEGHkvEGysV-GCECSPGGDLLVTGSADGRVLMY 500 5689995422567.6668***************9886 PP == domain 4 score: 5.7 bits; conditional E-value: 1.8 EEESS.SS.E.E.......EEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ss.v.t.......slafspdgawlasGsdDgtvriW 37 tl GH + v t s+ la++s+ g +iW sp|Q64LD2|WDR25_HUMAN 510 TLQGHtQAcVgTtyhpvlpSV--------LATCSWGGDMKIW 543 567885334432333333466........99*********** PP >> sp|Q562E7-6|WDR81_HUMAN Isoform 6 of WD repeat-containing protein 81 OS=Homo sapiens GN=WDR81 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.0 2e-07 1.7e-05 4 37 .. 414 448 .. 412 448 .. 0.92 2 ? 6.2 0.0 1.2 99 6 38 .] 465 496 .. 461 496 .. 0.68 3 ? 3.9 0.0 6.8 5.5e+02 10 29 .. 556 578 .. 546 585 .. 0.75 4 ? 7.7 0.2 0.43 35 7 38 .] 597 628 .. 591 628 .. 0.75 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 2e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l+++ GH + v ++a ++ ++++sGs+D+tvr+W sp|Q562E7-6|WDR81_HUMAN 414 LQSFPGHsGAVKCVAPLSSEDFFLSGSKDRTVRLW 448 6899***555************************* PP == domain 2 score: 6.2 bits; conditional E-value: 1.2 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 ++t H +sv + g++ ++ ++ Dg v++Wd sp|Q562E7-6|WDR81_HUMAN 465 VYTQHrKSVFFV-----GQLeapqHVVSC-DGAVHVWD 496 677888886555.....444444455578.*******9 PP == domain 3 score: 3.9 bits; conditional E-value: 6.8 S.SS..EEEEEEETTSSEEEEEE CS WD40 10 H.ss..vtslafspdgawlasGs 29 ++ v++la sp+g+ +++G sp|Q562E7-6|WDR81_HUMAN 556 GlNPglVRALAISPSGRSVVAGF 578 4556779************9993 PP == domain 4 score: 7.7 bits; conditional E-value: 0.43 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 + +H ++ + ++ +g+ l+s+s D+++ +W+ sp|Q562E7-6|WDR81_HUMAN 597 WPAHeGDilqIKAV----EGSVLVSSSSDHSLTVWK 628 56786666666777....7888998877*******6 PP >> tr|D6RBT6|D6RBT6_HUMAN Coatomer subunit beta' (Fragment) OS=Homo sapiens GN=COPB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.0 0.0082 0.67 13 38 .] 31 56 .. 18 56 .. 0.80 2 ! 32.6 0.0 5.7e-09 4.6e-07 4 38 .] 63 98 .. 60 98 .. 0.92 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.0082 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v++ +f ++w+++G dD +r+++ tr|D6RBT6|D6RBT6_HUMAN 31 VRAAKFVARKNWVVTGADDMQIRVFN 56 7777799999**************97 PP == domain 2 score: 32.6 bits; conditional E-value: 5.7e-09 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ +++Hs+ ++++a++p +++++++sdD +++Wd tr|D6RBT6|D6RBT6_HUMAN 63 VHMFEAHSDyIRCIAVHPTQPFILTSSDDMLIKLWD 98 899****556*************************9 PP >> tr|H0YI59|H0YI59_HUMAN WD repeat-containing protein 90 (Fragment) OS=Homo sapiens GN=WDR90 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.017 1.4 10 38 .] 4 33 .. 2 33 .. 0.67 2 ? 9.1 0.0 0.16 13 7 34 .. 85 113 .. 80 117 .. 0.77 3 ? 5.7 0.0 1.9 1.5e+02 15 38 .] 238 260 .. 222 260 .. 0.83 4 ! 15.4 0.0 0.0016 0.13 6 31 .. 271 296 .. 269 302 .. 0.84 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.017 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +v +la + la+ s D+tvriWd tr|H0YI59|H0YI59_HUMAN 4 HtAPVLALAMEQRRGQLATVSQDRTVRIWD 33 54556666433333338999*********9 PP == domain 2 score: 9.1 bits; conditional E-value: 0.16 EESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtv 34 t H + vt+l pdg++l+s++ g++ tr|H0YI59|H0YI59_HUMAN 85 HTCHrGAVTGLTATPDGRLLFSSCSQGSL 113 3578777************9865438876 PP == domain 3 score: 5.7 bits; conditional E-value: 1.9 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 sl s d ++l+ + +t+++Wd tr|H0YI59|H0YI59_HUMAN 238 SLTLSEDARFLLIAA-GRTIKVWD 260 566789999999999.*******9 PP == domain 4 score: 15.4 bits; conditional E-value: 0.0016 EEESS.SSEEEEEEETTSSEEEEEETT CS WD40 6 tltGH.ssvtslafspdgawlasGsdD 31 ++ GH +v ++afspd++ ++s++ D tr|H0YI59|H0YI59_HUMAN 271 VYIGHsEPVQAVAFSPDQQQVLSAG-D 296 799**777*************9887.5 PP >> sp|Q9UQ03-2|COR2B_HUMAN Isoform 2 of Coronin-2B OS=Homo sapiens GN=CORO2B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.1 0.00024 0.019 9 37 .. 80 110 .. 73 111 .. 0.77 2 ? 11.5 0.0 0.028 2.2 5 38 .] 126 161 .. 122 161 .. 0.76 3 ! 16.4 0.0 0.00078 0.063 1 36 [. 165 201 .. 165 203 .. 0.90 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 0.00024 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 GH ++v +++++p + +as+s+D +vriW sp|Q9UQ03-2|COR2B_HUMAN 80 GHqGNVLDIKWNPFIDNiIASCSEDTSVRIW 110 9*777****6555555556799********* PP == domain 2 score: 11.5 bits; conditional E-value: 0.028 EEEESSSS.EEEEE.EETTSSEEE.EEETTSEEEEEE CS WD40 5 rtltGHss.vtsla.fspdgawla.sGsdDgtvriWd 38 +l GHs v +l ++p + ++ s+++D +v iW+ sp|Q9UQ03-2|COR2B_HUMAN 126 LELHGHSRrV-GLVeWHPTTNNILfSAGYDYKVLIWN 161 6788994469.555599999996548888*******8 PP == domain 3 score: 16.4 bits; conditional E-value: 0.00078 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvri 36 g++++ ++ H++ + +++f+ dg++l++ ++D+++r+ sp|Q9UQ03-2|COR2B_HUMAN 165 GEPVKMIDCHTDvILCMSFNTDGSLLTTTCKDKKLRV 201 57889999**8856*************9999****98 PP >> sp|Q562E7-5|WDR81_HUMAN Isoform 5 of WD repeat-containing protein 81 OS=Homo sapiens GN=WDR81 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.6 0.0 2.1e-07 1.7e-05 4 37 .. 438 472 .. 436 472 .. 0.92 2 ? 6.2 0.0 1.3 1e+02 6 38 .] 489 520 .. 485 520 .. 0.68 3 ? 3.8 0.0 7.1 5.8e+02 10 29 .. 580 602 .. 570 609 .. 0.75 4 ? 7.6 0.2 0.45 37 7 38 .] 621 652 .. 615 652 .. 0.75 Alignments for each domain: == domain 1 score: 27.6 bits; conditional E-value: 2.1e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l+++ GH + v ++a ++ ++++sGs+D+tvr+W sp|Q562E7-5|WDR81_HUMAN 438 LQSFPGHsGAVKCVAPLSSEDFFLSGSKDRTVRLW 472 6899***555************************* PP == domain 2 score: 6.2 bits; conditional E-value: 1.3 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 ++t H +sv + g++ ++ ++ Dg v++Wd sp|Q562E7-5|WDR81_HUMAN 489 VYTQHrKSVFFV-----GQLeapqHVVSC-DGAVHVWD 520 677888886555.....444444455578.*******9 PP == domain 3 score: 3.8 bits; conditional E-value: 7.1 S.SS..EEEEEEETTSSEEEEEE CS WD40 10 H.ss..vtslafspdgawlasGs 29 ++ v++la sp+g+ +++G sp|Q562E7-5|WDR81_HUMAN 580 GlNPglVRALAISPSGRSVVAGF 602 4556779************9993 PP == domain 4 score: 7.6 bits; conditional E-value: 0.45 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 + +H ++ + ++ +g+ l+s+s D+++ +W+ sp|Q562E7-5|WDR81_HUMAN 621 WPAHeGDilqIKAV----EGSVLVSSSSDHSLTVWK 652 56786666666777....7888998877*******6 PP >> sp|Q9UQ03|COR2B_HUMAN Coronin-2B OS=Homo sapiens GN=CORO2B PE=2 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.1 0.00024 0.019 9 37 .. 85 115 .. 78 116 .. 0.77 2 ? 11.4 0.0 0.028 2.3 5 38 .] 131 166 .. 127 166 .. 0.76 3 ! 16.3 0.0 0.00079 0.064 1 36 [. 170 206 .. 170 208 .. 0.90 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 0.00024 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 GH ++v +++++p + +as+s+D +vriW sp|Q9UQ03|COR2B_HUMAN 85 GHqGNVLDIKWNPFIDNiIASCSEDTSVRIW 115 9*777****6555555556799********* PP == domain 2 score: 11.4 bits; conditional E-value: 0.028 EEEESSSS.EEEEE.EETTSSEEE.EEETTSEEEEEE CS WD40 5 rtltGHss.vtsla.fspdgawla.sGsdDgtvriWd 38 +l GHs v +l ++p + ++ s+++D +v iW+ sp|Q9UQ03|COR2B_HUMAN 131 LELHGHSRrV-GLVeWHPTTNNILfSAGYDYKVLIWN 166 6788994469.555599999996548888*******8 PP == domain 3 score: 16.3 bits; conditional E-value: 0.00079 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvri 36 g++++ ++ H++ + +++f+ dg++l++ ++D+++r+ sp|Q9UQ03|COR2B_HUMAN 170 GEPVKMIDCHTDvILCMSFNTDGSLLTTTCKDKKLRV 206 57889999**8856*************9999****98 PP >> sp|Q96JK2-2|DCAF5_HUMAN Isoform 2 of DDB1- and CUL4-associated factor 5 OS=Homo sapiens GN=DCAF5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.28 22 9 35 .. 18 44 .. 10 47 .. 0.81 2 ! 17.7 0.1 0.00029 0.023 7 38 .] 57 89 .. 51 89 .. 0.81 3 ? 6.7 0.1 0.87 71 15 37 .. 204 225 .. 191 226 .. 0.78 4 ! 17.0 0.0 0.00048 0.039 6 38 .] 246 279 .. 243 279 .. 0.91 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.28 SSSSEEEEEEETTSSEEEEEETTSEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvr 35 Hs++ +laf++ ++ ++sG+ D v sp|Q96JK2-2|DCAF5_HUMAN 18 HHSNIFCLAFNSGNTKVFSGGNDEQVI 44 4588****************9887765 PP == domain 2 score: 17.7 bits; conditional E-value: 0.00029 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + +H + v++l++sp ++ + as+sdDg v iWd sp|Q96JK2-2|DCAF5_HUMAN 57 F-AHeDAVYGLSVSPVNDNIfASSSDDGRVLIWD 89 4.79777*****9999999735779********9 PP == domain 3 score: 6.7 bits; conditional E-value: 0.87 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++a ++d+ +sGsdD ++++W sp|Q96JK2-2|DCAF5_HUMAN 204 CFAGDRDQYI-LSGSDDFNLYMW 225 5556666555.58********** PP == domain 4 score: 17.0 bits; conditional E-value: 0.00048 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH s v+ ++f+p+ +++s++ + ++iW+ sp|Q96JK2-2|DCAF5_HUMAN 246 VLKGHrSIVNQVRFNPHTYMICSSGVEKIIKIWS 279 799**7779************99999*******5 PP >> tr|B7Z6V3|B7Z6V3_HUMAN WD repeat-containing protein 81 OS=Homo sapiens GN=WDR81 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.1 0.0 1.6e-07 1.3e-05 4 37 .. 272 306 .. 270 306 .. 0.92 2 ? 6.6 0.0 0.94 76 6 38 .] 323 354 .. 319 354 .. 0.68 3 ? 4.3 0.0 5.2 4.2e+02 9 29 .. 413 436 .. 404 443 .. 0.75 4 ? 8.0 0.2 0.33 27 7 38 .] 455 486 .. 449 486 .. 0.75 Alignments for each domain: == domain 1 score: 28.1 bits; conditional E-value: 1.6e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l+++ GH + v ++a ++ ++++sGs+D+tvr+W tr|B7Z6V3|B7Z6V3_HUMAN 272 LQSFPGHsGAVKCVAPLSSEDFFLSGSKDRTVRLW 306 6899***555************************* PP == domain 2 score: 6.6 bits; conditional E-value: 0.94 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 ++t H +sv + g++ ++ ++ Dg v++Wd tr|B7Z6V3|B7Z6V3_HUMAN 323 VYTQHrKSVFFV-----GQLeapqHVVSC-DGAVHVWD 354 677888886555.....444444455578.*******9 PP == domain 3 score: 4.3 bits; conditional E-value: 5.2 SS.SS..EEEEEEETTSSEEEEEE CS WD40 9 GH.ss..vtslafspdgawlasGs 29 G ++ v++la sp+g+ +++G tr|B7Z6V3|B7Z6V3_HUMAN 413 GGlNPglVRALAISPSGRSVVAGF 436 44556779************9993 PP == domain 4 score: 8.0 bits; conditional E-value: 0.33 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 + +H ++ + ++ +g+ l+s+s D+++ +W+ tr|B7Z6V3|B7Z6V3_HUMAN 455 WPAHeGDilqIKAV----EGSVLVSSSSDHSLTVWK 486 56786666666777....7888998877*******6 PP >> tr|H3BRD4|H3BRD4_HUMAN Zinc finger protein 106 (Fragment) OS=Homo sapiens GN=ZNF106 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.016 1.3 4 36 .. 34 70 .. 31 72 .. 0.84 2 ! 13.6 0.1 0.0056 0.46 3 35 .. 78 109 .. 76 110 .. 0.75 3 ? 11.9 0.0 0.02 1.6 1 37 [. 116 151 .. 116 152 .. 0.73 4 ? 9.4 0.0 0.12 9.8 4 34 .. 159 188 .. 157 189 .. 0.78 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.016 EEEEESSSS..EEEEEEETTSSE..EEEEETTSEEEE CS WD40 4 lrtltGHss..vtslafspdgaw..lasGsdDgtvri 36 l +++ H++ v++la+ ++ga l+ Gs+D+t+ + tr|H3BRD4|H3BRD4_HUMAN 34 LEIFECHGPraVSCLATAQEGARklLVVGSYDCTISV 70 668999*6678*****999999998788*******87 PP == domain 2 score: 13.6 bits; conditional E-value: 0.0056 EEEEEESS.SS......EEEEEEETTSSEEEEEETTSEEE CS WD40 3 clrtltGH.ss......vtslafspdgawlasGsdDgtvr 35 +lrtl+GH + v++l ++sGs D++v+ tr|H3BRD4|H3BRD4_HUMAN 78 LLRTLEGHsKTilcmkvVNDL--------VFSGSSDQSVH 109 689*****7775555544666........889*88*9985 PP == domain 3 score: 11.9 bits; conditional E-value: 0.02 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+++r+++GH++ vt + + g+ +++++ D+ vr++ tr|H3BRD4|H3BRD4_HUMAN 116 GELVRIYKGHNHaVTVV--NILGKVMVTACLDKFVRVY 151 6789******8886555..112444788888*****98 PP == domain 4 score: 9.4 bits; conditional E-value: 0.12 EEEEESSSS.EEEEEEETTSSEEEEEETTSEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtv 34 l+++ GH++ + ++ +++ + +G++Dg++ tr|H3BRD4|H3BRD4_HUMAN 159 LQVYGGHKDmIMCMTIHKSM--IYTGCYDGSI 188 789****9999999554444..559*99**98 PP >> tr|F5H269|F5H269_HUMAN DmX-like protein 1 OS=Homo sapiens GN=DMXL1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.5 0.004 0.33 1 37 [. 159 196 .. 159 196 .. 0.87 2 ? 8.2 0.1 0.3 24 7 37 .. 227 267 .. 222 268 .. 0.81 3 ? 4.3 0.2 5 4e+02 6 38 .] 2854 2890 .. 2849 2890 .. 0.76 4 ? 5.2 0.1 2.7 2.2e+02 3 38 .] 2899 2935 .. 2897 2935 .. 0.86 5 ! 17.7 0.0 0.0003 0.024 6 38 .] 2944 2977 .. 2938 2977 .. 0.88 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.004 TEEEEEEESSSSEEEEEEETTSSEEEEEE.TTSEEEEE CS WD40 1 gqclrtltGHssvtslafspdgawlasGs.dDgtvriW 37 ++c++++++ s v+ ++fspdg ++a+++ dD+ +++W tr|F5H269|F5H269_HUMAN 159 WKCIWHCKTASQVHLMKFSPDGEFFATAGkDDCLLKVW 196 68889988887798889*********88757******* PP == domain 2 score: 8.2 bits; conditional E-value: 0.3 EESS.SSEEEEEEETTSSE.........EEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgaw.........lasGsdDgtvriW 37 + +H v+++++ + +++ l+++++D+ +r+W tr|F5H269|F5H269_HUMAN 227 YLAHpRAVNGFSWRKTSKYmprasvcnvLLTCCKDNVCRLW 267 5578555999988888888888888888889********** PP == domain 3 score: 4.3 bits; conditional E-value: 5 EEESS.SSEEEEEEETTSSEEEEEE...TTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGs...dDgtvriWd 38 t+ H + +++ f ++++++a+++ d+++v +Wd tr|F5H269|F5H269_HUMAN 2854 TWQCHnKTANDFVFVSSSSLIATAGlstDNRNVCLWD 2890 56678666788888899999997643459*******9 PP == domain 4 score: 5.2 bits; conditional E-value: 2.7 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +t H s+ t la+ p +++l+sG+++g +++d tr|F5H269|F5H269_HUMAN 2899 LVHAFTCHdSGATVLAYAPKHQLLISGGRKGFTYVFD 2935 7899****888999999***********998766665 PP == domain 5 score: 17.7 bits; conditional E-value: 0.0003 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H s+v ++a++p ++++Gs g+++iW+ tr|F5H269|F5H269_HUMAN 2944 LFQSHdSPVKAVAVDPTEEYFVTGSAEGNIKIWS 2977 4789*888*************************5 PP >> tr|E9PDG3|E9PDG3_HUMAN WD repeat-containing protein 81 OS=Homo sapiens GN=WDR81 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.0 0.0 1.6e-07 1.3e-05 4 37 .. 280 314 .. 278 314 .. 0.92 2 ? 6.6 0.0 0.95 77 6 38 .] 331 362 .. 327 362 .. 0.68 3 ? 4.2 0.0 5.3 4.3e+02 9 29 .. 421 444 .. 412 451 .. 0.75 4 ? 8.0 0.2 0.34 27 7 38 .] 463 494 .. 457 494 .. 0.75 Alignments for each domain: == domain 1 score: 28.0 bits; conditional E-value: 1.6e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l+++ GH + v ++a ++ ++++sGs+D+tvr+W tr|E9PDG3|E9PDG3_HUMAN 280 LQSFPGHsGAVKCVAPLSSEDFFLSGSKDRTVRLW 314 6899***555************************* PP == domain 2 score: 6.6 bits; conditional E-value: 0.95 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 ++t H +sv + g++ ++ ++ Dg v++Wd tr|E9PDG3|E9PDG3_HUMAN 331 VYTQHrKSVFFV-----GQLeapqHVVSC-DGAVHVWD 362 677888886555.....444444455578.*******9 PP == domain 3 score: 4.2 bits; conditional E-value: 5.3 SS.SS..EEEEEEETTSSEEEEEE CS WD40 9 GH.ss..vtslafspdgawlasGs 29 G ++ v++la sp+g+ +++G tr|E9PDG3|E9PDG3_HUMAN 421 GGlNPglVRALAISPSGRSVVAGF 444 44556779************9993 PP == domain 4 score: 8.0 bits; conditional E-value: 0.34 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 + +H ++ + ++ +g+ l+s+s D+++ +W+ tr|E9PDG3|E9PDG3_HUMAN 463 WPAHeGDilqIKAV----EGSVLVSSSSDHSLTVWK 494 56786666666777....7888998877*******6 PP >> sp|O95170-2|CDRT1_HUMAN Isoform 2 of CMT1A duplicated region transcript 1 protein OS=Homo sapiens GN=CDRT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.2 0.014 1.1 24 38 .] 7 21 .. 2 21 .. 0.87 2 ? 9.8 0.1 0.094 7.6 1 37 [. 25 59 .. 25 60 .. 0.89 3 ! 16.9 0.2 0.00055 0.044 2 37 .. 65 99 .. 64 100 .. 0.83 4 ? 10.3 0.0 0.066 5.3 2 38 .] 107 141 .. 106 141 .. 0.73 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 l+sG++D+ v++Wd sp|O95170-2|CDRT1_HUMAN 7 RLVSGGRDCQVKVWD 21 5789**********9 PP == domain 2 score: 9.8 bits; conditional E-value: 0.094 TEEEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssv..tslafspdgawlasGsdDgtvriW 37 g+cl+t++ H +++ t + + ++++s+++ g v++W sp|O95170-2|CDRT1_HUMAN 25 GKCLKTFR-HkDPIlaTRI----NDTYIVSSCERGLVKVW 59 79*****9.9666778999....9*****9999******* PP == domain 3 score: 16.9 bits; conditional E-value: 0.00055 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriW 37 q+++tl+GH + v +l f +w l+sGs Dg v+ W sp|O95170-2|CDRT1_HUMAN 65 QLVKTLSGHeGAVKCLFF---DQWhLLSGSTDGLVMAW 99 789******888****54...477557********999 PP == domain 4 score: 10.3 bits; conditional E-value: 0.066 EEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +cl ++ H + v ++ ++ ++s++ Dg++ri++ sp|O95170-2|CDRT1_HUMAN 107 RCLMAFK-HpKEVLDV------SLlflrVISACADGKIRIYN 141 6777887.87888888......664555456666******98 PP >> sp|Q8NFH4|NUP37_HUMAN Nucleoporin Nup37 OS=Homo sapiens GN=NUP37 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.84 68 2 37 .. 64 107 .. 63 108 .. 0.80 2 ! 23.4 0.0 4.6e-06 0.00037 5 38 .] 118 153 .. 114 153 .. 0.86 3 ? 7.1 0.0 0.66 54 15 38 .] 170 194 .. 156 194 .. 0.80 4 ? 8.8 0.4 0.19 15 4 37 .. 282 322 .. 279 323 .. 0.79 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.84 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriW 37 ++lrt+ H v ++a+sp+ ++ ++++ D ++r++ sp|Q8NFH4|NUP37_HUMAN 64 KTLRTF-HHgVRVDGIAWSPETRLdslppvikFCTSAADMKIRLF 107 567777.4744489***************988677767****986 PP == domain 2 score: 23.4 bits; conditional E-value: 4.6e-06 EEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 ++l+GH +++++l f+p +as sdD+t+riW+ sp|Q8NFH4|NUP37_HUMAN 118 KVLEGHtDFINGLVFDPKEGQeIASVSDDHTCRIWN 153 6899**777****9888888879988*********8 PP == domain 3 score: 7.1 bits; conditional E-value: 0.66 EEEEETTSSE.EEEEETTSEEEEEE CS WD40 15 slafspdgaw.lasGsdDgtvriWd 38 s++++p+ ++ l+ + ++gt+r++d sp|Q8NFH4|NUP37_HUMAN 170 SVCWHPEETFkLMVAEKNGTIRFYD 194 99********8678999******98 PP == domain 4 score: 8.8 bits; conditional E-value: 0.19 EEEEESS.SS.......E.EEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ss.......v.tslafspdgawlasGsdDgtvriW 37 +++l GH ++ v ++l++++ ++ + G+ D+++ +W sp|Q8NFH4|NUP37_HUMAN 282 IHHL-GHpQPilmgsvaVgSGLSWHRTLPLCVIGG-DHKLLFW 322 5777.9988866666555667779999999999**.******* PP >> tr|H0YLM8|H0YLM8_HUMAN DmX-like protein 2 (Fragment) OS=Homo sapiens GN=DMXL2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.6 1.8 1.4e+02 8 38 .] 996 1030 .. 990 1030 .. 0.72 2 ? 10.8 0.1 0.046 3.7 3 38 .] 1039 1075 .. 1037 1075 .. 0.85 3 ! 22.5 0.0 8.7e-06 0.0007 2 37 .. 1080 1116 .. 1079 1117 .. 0.94 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 1.8 ESS.SSEEEEEEETTSSEEEEEE...TTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGs...dDgtvriWd 38 H + +++af +++++a+++ d+++v +Wd tr|H0YLM8|H0YLM8_HUMAN 996 QCHsKATSDFAFITSSSLVATSGhsnDNRNVCLWD 1030 567444567778888899996543678*******9 PP == domain 2 score: 10.8 bits; conditional E-value: 0.046 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++ +t H++ t l++ p +++l+sG+++g+v i+d tr|H0YLM8|H0YLM8_HUMAN 1039 LIHGFTCHDHgATVLQYAPKQQLLISGGRKGHVCIFD 1075 57778999445888899******************98 PP == domain 3 score: 22.5 bits; conditional E-value: 8.7e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 q+++t+ +H s + +la +p+ ++++Gs g++++W tr|H0YLM8|H0YLM8_HUMAN 1080 QLIHTFQAHdSAIKALALDPYEEYFTTGSAEGNIKVW 1116 899******777************************* PP >> sp|Q562E7-3|WDR81_HUMAN Isoform 3 of WD repeat-containing protein 81 OS=Homo sapiens GN=WDR81 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 0.0 2.7e-07 2.2e-05 4 37 .. 590 624 .. 588 624 .. 0.92 2 ? 5.9 0.0 1.6 1.3e+02 6 38 .] 641 672 .. 637 672 .. 0.68 3 ? 3.5 0.0 8.9 7.2e+02 10 29 .. 732 754 .. 722 761 .. 0.75 4 ? 7.3 0.2 0.56 46 7 38 .] 773 804 .. 767 804 .. 0.75 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 2.7e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l+++ GH + v ++a ++ ++++sGs+D+tvr+W sp|Q562E7-3|WDR81_HUMAN 590 LQSFPGHsGAVKCVAPLSSEDFFLSGSKDRTVRLW 624 6899***555************************* PP == domain 2 score: 5.9 bits; conditional E-value: 1.6 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 ++t H +sv + g++ ++ ++ Dg v++Wd sp|Q562E7-3|WDR81_HUMAN 641 VYTQHrKSVFFV-----GQLeapqHVVSC-DGAVHVWD 672 677888886555.....444444455578.*******9 PP == domain 3 score: 3.5 bits; conditional E-value: 8.9 S.SS..EEEEEEETTSSEEEEEE CS WD40 10 H.ss..vtslafspdgawlasGs 29 ++ v++la sp+g+ +++G sp|Q562E7-3|WDR81_HUMAN 732 GlNPglVRALAISPSGRSVVAGF 754 4556779************9993 PP == domain 4 score: 7.3 bits; conditional E-value: 0.56 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 + +H ++ + ++ +g+ l+s+s D+++ +W+ sp|Q562E7-3|WDR81_HUMAN 773 WPAHeGDilqIKAV----EGSVLVSSSSDHSLTVWK 804 56786666666777....7888998877*******6 PP >> sp|O60336-4|MABP1_HUMAN Isoform 4 of Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens GN=MAPKBP1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 2.9 2.3e+02 7 36 .. 18 51 .. 10 53 .. 0.71 2 ? 11.1 0.0 0.036 2.9 3 36 .. 60 85 .. 58 96 .. 0.62 3 ? 8.4 0.0 0.25 21 15 38 .] 167 190 .. 149 190 .. 0.75 4 ! 17.3 0.3 0.00038 0.031 1 37 [. 194 231 .. 194 232 .. 0.88 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 2.9 EESS.SSEEEEE...EETTSSE...EEEEETTSEEEE CS WD40 7 ltGH.ssvtsla...fspdgaw...lasGsdDgtvri 36 ++H s + +l + las+s+D+ +++ sp|O60336-4|MABP1_HUMAN 18 VEAHdSEILCLEyskPDT---GlklLASASRDRLIHV 51 579966699997533333...24558999****9987 PP == domain 2 score: 11.1 bits; conditional E-value: 0.036 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvri 36 +++tl+ H ss+t+++ + ++s Dg vr+ sp|O60336-4|MABP1_HUMAN 60 LQQTLDEHsSSITAVK------F--AAS-DGQVRM 85 7899****888****4......4..344.444443 PP == domain 3 score: 8.4 bits; conditional E-value: 0.25 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++++p+g ++a+++ D+++ i+d sp|O60336-4|MABP1_HUMAN 167 KVQTDPSGIYIATSCSDKNLSIFD 190 6789*******96644*****998 PP == domain 4 score: 17.3 bits; conditional E-value: 0.00038 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 g+c+ t GHs vt+++fs d + l+s s D + +W sp|O60336-4|MABP1_HUMAN 194 GECVATMFGHSEiVTGMKFSNDCKHLISVSGDSCIFVW 231 68999999**6657************98766******* PP >> tr|C9JJ54|C9JJ54_HUMAN WD repeat and FYVE domain-containing protein 1 (Fragment) OS=Homo sapiens GN=WDFY1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 0.0009 0.073 4 37 .. 17 51 .. 15 51 .. 0.83 2 ? 7.7 0.2 0.43 35 5 34 .. 65 95 .. 62 96 .. 0.80 3 ! 26.0 0.6 7e-07 5.6e-05 4 38 .] 149 184 .. 146 184 .. 0.92 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 0.0009 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l +++GH + vt+ p + ++++s+D+t+r+W tr|C9JJ54|C9JJ54_HUMAN 17 LSKIEGHqDAVTAALLIPKEDGVITASEDRTIRVW 51 56679**666*99977777777899********** PP == domain 2 score: 7.7 bits; conditional E-value: 0.43 EEEESS.SSEEEEEEETTSSEEE.EEETTSEE CS WD40 5 rtltGH.ssvtslafspdgawla.sGsdDgtv 34 +t H + v+++ fs w++ +G+ D+ v tr|C9JJ54|C9JJ54_HUMAN 65 HTMASHqNRVSAIIFSLATEWVIsTGH-DKCV 95 667789888*9999999****983566.9987 PP == domain 3 score: 26.0 bits; conditional E-value: 7e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++tl+GH +sv +l ++p +++l+sG D+++ +Wd tr|C9JJ54|C9JJ54_HUMAN 149 ITTLKGHeGSVACLWWDPIQRLLFSGASDNSIIMWD 184 789****999****************66*******9 PP >> tr|Q5TFK1|Q5TFK1_HUMAN Eukaryotic translation initiation factor 3 subunit I (Fragment) OS=Homo sapiens GN=EIF3I PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 0.001 0.083 7 37 .. 6 37 .. 3 37 .. 0.94 2 ! 29.4 1.6 5.8e-08 4.7e-06 2 38 .] 43 80 .. 42 80 .. 0.86 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 0.001 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 l GH s+t ++++++g++l++ +D+ v +W tr|Q5TFK1|Q5TFK1_HUMAN 6 LQGHeRSITQIKYNREGDLLFTVAKDPIVNVW 37 68**888************************* PP == domain 2 score: 29.4 bits; conditional E-value: 5.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + l+t+ GH + v++++ + d + +++Gs D+++r+Wd tr|Q5TFK1|Q5TFK1_HUMAN 43 ERLGTYMGHtGAVWCVDADWDTKHVLTGSADNSCRLWD 80 6689999**777****7777777799***********9 PP >> tr|C9J1X0|C9J1X0_HUMAN Uncharacterized protein OS=Homo sapiens GN=WDR91 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.2 0.099 8 7 38 .] 369 401 .. 365 401 .. 0.84 2 ! 18.0 0.0 0.00023 0.019 13 38 .] 530 555 .. 517 555 .. 0.87 3 ? 10.1 0.0 0.077 6.2 3 38 .] 561 597 .. 559 597 .. 0.88 4 ? 7.6 0.1 0.45 36 6 36 .. 671 704 .. 666 704 .. 0.75 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.099 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H ss+ +++++ +g+ +as + Dg +++W+ tr|C9J1X0|C9J1X0_HUMAN 369 YGEHhSSIMHCRVDCSGRRVASLDVDGVIKVWS 401 6667799************975478*******5 PP == domain 2 score: 18.0 bits; conditional E-value: 0.00023 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 +++ af+++g++l++G Dg +r++d tr|C9J1X0|C9J1X0_HUMAN 530 INCTAFNHNGNLLVTGAADGVIRLFD 555 89**************99******98 PP == domain 3 score: 10.1 bits; conditional E-value: 0.077 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++++H + v+s+ fs d + + s ++Dg+ W+ tr|C9J1X0|C9J1X0_HUMAN 561 CAMSWRAHyGEVYSVEFSYDENTVYSIGEDGKFIQWN 597 778999**999*************95477****9998 PP == domain 4 score: 7.6 bits; conditional E-value: 0.45 EEESS.SSEEEEEEETTSSE.........EEEEETTSEEEE CS WD40 6 tltGH.ssvtslafspdgaw.........lasGsdDgtvri 36 +l GH +v + +w l ++s+Dg++++ tr|C9J1X0|C9J1X0_HUMAN 671 SLGGHrAPVVTV------DWstamdcgtcL-TASMDGKIKL 704 678**99999**......665555558845.6778****97 PP >> tr|B4DT55|B4DT55_HUMAN WD repeat-containing protein 41 OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 0.0016 0.13 2 38 .] 20 64 .. 19 64 .. 0.73 2 ! 21.9 0.0 1.4e-05 0.0011 3 37 .. 262 294 .. 260 295 .. 0.88 3 ? 9.3 0.1 0.14 11 3 38 .] 342 377 .. 340 377 .. 0.76 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0016 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd tr|B4DT55|B4DT55_HUMAN 20 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 64 6788999**7779999855555544444444779999*******9 PP == domain 2 score: 21.9 bits; conditional E-value: 1.4e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++t +H s+v ++a p+ +++ s+s+Dg+vriW tr|B4DT55|B4DT55_HUMAN 262 CQKT--AHdSNVLHVARLPNRQLI-SCSEDGSVRIW 294 6777..9*777************7.7999******* PP == domain 3 score: 9.3 bits; conditional E-value: 0.14 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ l GH ssv + + d+ ++ ++s D+ + +W+ tr|B4DT55|B4DT55_HUMAN 342 LIGDLIGHsSSVEMFLYFEDHGLV-TCSADHLIILWK 377 567789**7779666566666665.7888*******6 PP >> sp|A6NE52|K1875_HUMAN WD repeat-containing protein KIAA1875 OS=Homo sapiens GN=KIAA1875 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.67 54 13 37 .. 295 319 .. 287 320 .. 0.70 2 ! 21.3 0.0 2.1e-05 0.0017 3 38 .] 325 361 .. 323 361 .. 0.91 3 ? 7.0 0.1 0.7 56 8 37 .. 594 623 .. 587 624 .. 0.68 4 ? 12.5 0.3 0.013 1.1 8 37 .. 689 716 .. 682 717 .. 0.83 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.67 EEEEEEETTSSE......EEEEETTSEEEEE CS WD40 13 vtslafspdgaw......lasGsdDgtvriW 37 +++l a+ ++++s+D tv++W sp|A6NE52|K1875_HUMAN 295 ISDL------AYceeveaMVTASRDSTVKVW 319 6677......44444444679999******* PP == domain 2 score: 21.3 bits; conditional E-value: 2.1e-05 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ GH ++vt++ + p+ ++++s+s Dgt+r Wd sp|A6NE52|K1875_HUMAN 325 IRMVFVGHtGPVTAMTVLPNTTLVLSASQDGTLRTWD 361 567899**888*************************9 PP == domain 3 score: 7.0 bits; conditional E-value: 0.7 ESSSS..EEEEEEETTSSE...EEEEETTSEEEEE CS WD40 8 tGHss..vtslafspdgaw...lasGsdDgtvriW 37 ++Hs+ v ++ ++w ++sG+ D tv++W sp|A6NE52|K1875_HUMAN 594 EAHSPgpVVAI----ASTWnsiVSSGG-DLTVKMW 623 58844457788....445566467889.******* PP == domain 4 score: 12.5 bits; conditional E-value: 0.013 ESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriW 37 t H +t+l+ +p ++ a++s D+tvriW sp|A6NE52|K1875_HUMAN 689 TDH--ITGLCCCPTLKLYACSSLDCTVRIW 716 567..999999999999888899******* PP >> tr|H7C3R4|H7C3R4_HUMAN WD repeat-containing protein 62 (Fragment) OS=Homo sapiens GN=WDR62 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.0 4.2e-05 0.0034 2 38 .] 124 163 .. 123 163 .. 0.90 2 ! 13.8 0.0 0.0051 0.41 6 38 .] 172 207 .. 167 207 .. 0.80 3 ? 11.2 0.1 0.033 2.7 13 37 .. 223 246 .. 213 246 .. 0.88 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 4.2e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG..sdDgtvriWd 38 ++++++ + +s ++lafspdg+++++G + + vriWd tr|H7C3R4|H7C3R4_HUMAN 124 KQQHIFNTArKSLSALAFSPDGKYIVTGenGHRPAVRIWD 163 678999988899***************98866*******9 PP == domain 2 score: 13.8 bits; conditional E-value: 0.0051 EEESSSS.EEEEEEETTSSEEEE.E..ETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlas.G..sdDgtvriWd 38 + GH+ v ++afsp+ + ++s G + D + +Wd tr|H7C3R4|H7C3R4_HUMAN 172 EMLGHKYgVACVAFSPNMKHIVSmGyqH-DMVLNVWD 207 5569*555************99656444.*******9 PP == domain 3 score: 11.2 bits; conditional E-value: 0.033 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 v +l+fs d++++++ + +++vr+W tr|H7C3R4|H7C3R4_HUMAN 223 VIALSFSEDSSYFVTVG-NRHVRFW 246 45899**********9*.******* PP >> tr|C9JVF0|C9JVF0_HUMAN Transducin beta-like protein 2 OS=Homo sapiens GN=TBL2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.7 0.1 5.9e-10 4.8e-08 7 38 .] 86 118 .. 76 118 .. 0.90 2 ? 10.7 0.0 0.047 3.8 10 38 .] 187 216 .. 179 216 .. 0.79 Alignments for each domain: == domain 1 score: 35.7 bits; conditional E-value: 5.9e-10 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+ H +++++++fs++g++la++ dD+t+riW+ tr|C9JVF0|C9JVF0_HUMAN 86 LKSHsGNISCMDFSSNGKYLATCADDRTIRIWS 118 6789555*************************5 PP == domain 2 score: 10.7 bits; conditional E-value: 0.047 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +v ++ g++++++s D tv iW+ tr|C9JVF0|C9JVF0_HUMAN 187 HkAPVIDIGIANTGKFIMTASSDTTVLIWS 216 64445566678899***99877*******5 PP >> sp|A4D1P6|WDR91_HUMAN WD repeat-containing protein 91 OS=Homo sapiens GN=WDR91 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 0.2 0.1 8.5 7 38 .] 404 436 .. 400 436 .. 0.84 2 ! 18.0 0.0 0.00024 0.02 13 38 .] 565 590 .. 552 590 .. 0.87 3 ? 10.0 0.0 0.081 6.6 3 38 .] 596 632 .. 594 632 .. 0.88 4 ? 7.6 0.1 0.47 38 6 36 .. 706 739 .. 701 739 .. 0.75 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.1 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H ss+ +++++ +g+ +as + Dg +++W+ sp|A4D1P6|WDR91_HUMAN 404 YGEHhSSIMHCRVDCSGRRVASLDVDGVIKVWS 436 6667799************975478*******5 PP == domain 2 score: 18.0 bits; conditional E-value: 0.00024 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 +++ af+++g++l++G Dg +r++d sp|A4D1P6|WDR91_HUMAN 565 INCTAFNHNGNLLVTGAADGVIRLFD 590 89**************99******98 PP == domain 3 score: 10.0 bits; conditional E-value: 0.081 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c ++++H + v+s+ fs d + + s ++Dg+ W+ sp|A4D1P6|WDR91_HUMAN 596 CAMSWRAHyGEVYSVEFSYDENTVYSIGEDGKFIQWN 632 778999**999*************95477****9998 PP == domain 4 score: 7.6 bits; conditional E-value: 0.47 EEESS.SSEEEEEEETTSSE.........EEEEETTSEEEE CS WD40 6 tltGH.ssvtslafspdgaw.........lasGsdDgtvri 36 +l GH +v + +w l ++s+Dg++++ sp|A4D1P6|WDR91_HUMAN 706 SLGGHrAPVVTV------DWstamdcgtcL-TASMDGKIKL 739 678**99999**......665555558845.6778****97 PP >> sp|Q969U6|FBXW5_HUMAN F-box/WD repeat-containing protein 5 OS=Homo sapiens GN=FBXW5 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.1 0.4 3.1e-07 2.5e-05 4 38 .] 85 120 .. 82 120 .. 0.91 2 ? 6.5 0.0 1 83 16 38 .] 479 497 .. 455 497 .. 0.78 3 ? 11.1 0.0 0.036 2.9 4 37 .. 504 538 .. 501 539 .. 0.80 Alignments for each domain: == domain 1 score: 27.1 bits; conditional E-value: 3.1e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++tl+ H + v +l+fs++g +as+s+D+tv+iW+ sp|Q969U6|FBXW5_HUMAN 85 VQTLREHtDQVLHLSFSHSGYQFASCSKDCTVKIWS 120 789****666*************************5 PP == domain 2 score: 6.5 bits; conditional E-value: 1 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 + + +++asG +D++ +iWd sp|Q969U6|FBXW5_HUMAN 479 V----SRDFVASGAEDRHGYIWD 497 4....6788*************9 PP == domain 3 score: 11.1 bits; conditional E-value: 0.036 EEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawla.sGsdDgtvriW 37 l l+ H + v+s+ fsp + l+ ++sdD t++ W sp|Q969U6|FBXW5_HUMAN 504 LARLR-HEDvVNSVVFSPQEQELLlTASDDATIKAW 538 55565.86657********9997559********99 PP >> sp|Q9P2S5|WRP73_HUMAN WD repeat-containing protein WRAP73 OS=Homo sapiens GN=WRAP73 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.93 75 16 28 .. 14 26 .. 4 33 .. 0.81 2 ? 3.9 0.0 6.5 5.3e+02 1 26 [. 168 194 .. 168 206 .. 0.86 3 ! 23.0 0.0 6.1e-06 0.00049 2 36 .. 212 249 .. 211 251 .. 0.84 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.93 EEEETTSSEEEEE CS WD40 16 lafspdgawlasG 28 ++fspdg++las+ sp|Q9P2S5|WRP73_HUMAN 14 CKFSPDGKYLASC 26 35*********98 PP == domain 2 score: 3.9 bits; conditional E-value: 6.5 TEEEEEEESS.SSEEEEEEETTSSEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawla 26 +q+lr++++ ++ t++ + p+g la sp|Q9P2S5|WRP73_HUMAN 168 WQLLRHFDTDtQDLTGIEWAPNGCVLA 194 6899999987788**********9985 PP == domain 3 score: 23.0 bits; conditional E-value: 6.1e-06 EEEEEEESSSS...EEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGHss...vtslafspdgawlasGsdDgtvri 36 ++l t+++ + + s+a+sp++++la Gs+Dg+vri sp|Q9P2S5|WRP73_HUMAN 212 RLLSTYSAYEWslgIKSVAWSPSSQFLAVGSYDGKVRI 249 567778777334679**********************9 PP >> sp|Q6PJI9|WDR59_HUMAN WD repeat-containing protein 59 OS=Homo sapiens GN=WDR59 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.2 0.0021 0.17 4 38 .] 98 134 .. 95 134 .. 0.85 2 ? 12.0 0.2 0.019 1.5 20 38 .] 159 176 .. 143 176 .. 0.76 3 ! 23.7 0.3 3.6e-06 0.00029 8 38 .] 188 220 .. 182 220 .. 0.89 4 ? 9.2 0.1 0.15 12 2 37 .. 273 314 .. 272 315 .. 0.74 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 0.0021 EEEEESSSS.EEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgaw.......lasGsdDgtvriWd 38 +tl GH+ +++l +w l+++s D ++iWd sp|Q6PJI9|WDR59_HUMAN 98 GTTLQGHTRvISDL------DWavfepdlLVTSSVDTYIYIWD 134 57899**7767***......8888888888899*********9 PP == domain 2 score: 12.0 bits; conditional E-value: 0.019 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 ++ + la+++ Dg vriWd sp|Q6PJI9|WDR59_HUMAN 159 KNANCLATSH-DGDVRIWD 176 3445588888.*******9 PP == domain 3 score: 23.7 bits; conditional E-value: 3.6e-06 ESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGsdDgtvriWd 38 +H s +++l+++pd+ + a++s D++v++Wd sp|Q6PJI9|WDR59_HUMAN 188 AAHlSKIHGLDWHPDSEHIlATSSQDNSVKFWD 220 589999************626889********9 PP == domain 4 score: 9.2 bits; conditional E-value: 0.15 EEEEEEESSSS.EEEEE......EETTSSEEEEE.ETTSEEEEE CS WD40 2 qclrtltGHss.vtsla......fspdgawlasG.sdDgtvriW 37 ++++t+ GH++ v ++ s+d +++ s+D+t+r+W sp|Q6PJI9|WDR59_HUMAN 273 TPVHTFVGHDDvVLEFQwrkqkeGSKDYQLV--TwSRDQTLRMW 314 589******7756888556666666666665..5588******* PP >> tr|H3BT67|H3BT67_HUMAN Katanin p80 WD40 repeat-containing subunit B1 (Fragment) OS=Homo sapiens GN=KATNB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.1 0.00019 0.015 4 38 .] 13 49 .. 10 49 .. 0.88 2 ! 28.0 0.0 1.7e-07 1.4e-05 2 38 .] 54 91 .. 53 91 .. 0.93 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 0.00019 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 l+++ +H s+v+sl +g++la+G+dD+ v +W+ tr|H3BT67|H3BT67_HUMAN 13 LQEIVAHaSNVSSLVlGKASGRLLATGGDDCRVNLWS 49 667779*888*999999999****************5 PP == domain 2 score: 28.0 bits; conditional E-value: 1.7e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ +ltGH s+v s++ + ++++Gs g++r+Wd tr|H3BT67|H3BT67_HUMAN 54 NCIMSLTGHtSPVESVRLNTPEELIVAGSQSGSIRVWD 91 79*******999****98888888999**********9 PP >> tr|B3KR43|B3KR43_HUMAN WD repeat-containing protein 20 OS=Homo sapiens GN=WDR20 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 0.0011 0.091 13 38 .] 99 124 .. 86 124 .. 0.85 2 ! 22.3 0.2 1.1e-05 0.00086 13 38 .] 141 166 .. 129 166 .. 0.84 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0011 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +afspdg++la+ s Dg +r+++ tr|B3KR43|B3KR43_HUMAN 99 LNEFAFSPDGKFLACVSQDGFLRVFN 124 67789********988********97 PP == domain 2 score: 22.3 bits; conditional E-value: 1.1e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ tr|B3KR43|B3KR43_HUMAN 141 LLCVCWSPDGKYIVTGGEDDLVTVWS 166 67***********************5 PP >> sp|Q96MX6|WDR92_HUMAN WD repeat-containing protein 92 OS=Homo sapiens GN=WDR92 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 3.3 2.6e+02 21 38 .] 79 96 .. 66 96 .. 0.85 2 ! 21.3 0.0 2.1e-05 0.0017 3 38 .] 103 145 .. 101 145 .. 0.74 3 ! 13.9 0.1 0.0045 0.37 7 36 .. 319 348 .. 314 348 .. 0.81 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 3.3 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +++la+G+ g+++iW+ sp|Q96MX6|WDR92_HUMAN 79 QQRYLATGDFGGNLHIWN 96 5689****99*******8 PP == domain 2 score: 21.3 bits; conditional E-value: 2.1e-05 EEEEEESSSS.EEEEE......EETTSSE.....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtsla......fspdgaw.....lasGsdDgtvriWd 38 ++++ +GH+ +++++ +++Gs+Dgtv++Wd sp|Q96MX6|WDR92_HUMAN 103 PVYSVKGHKEiINAIDgigglgI-----GegapeIVTGSRDGTVKVWD 145 678999**7757*9955555543.....05555599***********9 PP == domain 3 score: 13.9 bits; conditional E-value: 0.0045 EESSSSEEEEEEETTSSEEEEE.ETTSEEEE CS WD40 7 ltGHssvtslafspdgawlasG.sdDgtvri 36 l+++ +++sl++spd++ l+ + s D+tvr+ sp|Q96MX6|WDR92_HUMAN 319 LSTQ-PISSLDWSPDKRGLCVCsSFDQTVRV 348 5555.8************9755267****97 PP >> tr|H0YN02|H0YN02_HUMAN WD repeat-containing protein 72 (Fragment) OS=Homo sapiens GN=WDR72 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 0.0 0.46 38 10 38 .] 18 45 .. 12 45 .. 0.92 2 ? 9.5 0.0 0.12 9.6 9 38 .] 60 93 .. 49 93 .. 0.85 3 ? 3.6 0.1 8.3 6.7e+02 18 36 .. 412 430 .. 396 430 .. 0.75 4 ! 13.6 0.5 0.0058 0.47 5 38 .] 455 495 .. 452 495 .. 0.88 5 ! 14.5 0.1 0.003 0.24 2 37 .. 548 584 .. 547 585 .. 0.90 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.46 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 H s+t++ +d++ +++Gs g + +W+ tr|H0YN02|H0YN02_HUMAN 18 H-SITAIMITDDQRTIVTGSQEGQLCLWN 45 6.79999999******************8 PP == domain 2 score: 9.5 bits; conditional E-value: 0.12 SS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriWd 38 GH svt+la + +++++s+ ++g +W+ tr|H0YN02|H0YN02_HUMAN 60 GHsASVTCLArarDFSKQPYIVSAAENGEMCVWN 93 9*777********6667777889999*******8 PP == domain 3 score: 3.6 bits; conditional E-value: 8.3 EETTSSEEEEEETTSEEEE CS WD40 18 fspdgawlasGsdDgtvri 36 + p+ + l++G++Dgt+ i tr|H0YN02|H0YN02_HUMAN 412 YIPSLDKLICGCEDGTIII 430 4455588999******976 PP == domain 4 score: 13.6 bits; conditional E-value: 0.0058 EEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtsla......fspdgawlasGsdDgtvriWd 38 ++l+GH +svtsl d++w++sG+ D v +Wd tr|H0YN02|H0YN02_HUMAN 455 KVLKGHhQSVTSLLyphglsSKLDQSWMLSGDLDSCVILWD 495 6799**999*98887777779999999****99*******9 PP == domain 5 score: 14.5 bits; conditional E-value: 0.003 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +cl + + H ++v+ ++++p ++l+ G+ D +v+iW tr|H0YN02|H0YN02_HUMAN 548 SCLLHARKHlFPVRMIKWHPVENFLIVGCADDSVYIW 584 577777889999****************99******* PP >> tr|D6RF23|D6RF23_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 0.1 1.1e-06 8.6e-05 1 38 [] 8 44 .. 8 44 .. 0.88 2 ! 21.0 0.0 2.7e-05 0.0022 13 37 .. 70 94 .. 56 95 .. 0.89 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 1.1e-06 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g++l+tl+G + +++l+fsp+ wl++++ ++++iWd tr|D6RF23|D6RF23_HUMAN 8 GKHLYTLDGG-DiINALCFSPNRYWLCAAT-GPSIKIWD 44 5778899887.448************9888.*******9 PP == domain 2 score: 21.0 bits; conditional E-value: 2.7e-05 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 tsla+s dg+ l++G D+ vr+W tr|D6RF23|D6RF23_HUMAN 70 CTSLAWSADGQTLFAGYTDNLVRVW 94 59**************88******* PP >> sp|Q99570|PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 OS=Homo sapiens GN=PIK3R4 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.2 1.2e-06 0.0001 4 38 .] 986 1021 .. 983 1021 .. 0.91 2 ? 8.6 0.0 0.22 18 13 38 .] 1245 1269 .. 1233 1269 .. 0.69 3 ! 17.6 0.1 0.00032 0.026 9 38 .] 1327 1358 .] 1321 1358 .] 0.87 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 1.2e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +l H s v+ +++s++++++a++s Dgtv+iW+ sp|Q99570|PI3R4_HUMAN 986 VAHLHEHkSAVNRIRVSDEHSLFATCSNDGTVKIWN 1021 678999*666*************************8 PP == domain 2 score: 8.6 bits; conditional E-value: 0.22 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 +++ + + +l++Gs D ++r+Wd sp|Q99570|PI3R4_HUMAN 1245 IYCSPADGNPILLTAGS-DMKIRFWD 1269 43333555566678899.*******9 PP == domain 3 score: 17.6 bits; conditional E-value: 0.00032 SS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla.fspdgawlasGsdDgtvriWd 38 GH + +t++a f+ + +++++s+Dg v++W+ sp|Q99570|PI3R4_HUMAN 1327 GHhDIITDVAtFQTTQGFIVTASRDGIVKVWK 1358 894448*************************6 PP >> tr|G5E9A7|G5E9A7_HUMAN Dystrophia myotonica WD repeat-containing protein OS=Homo sapiens GN=DMWD PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.0 0.0077 0.62 13 37 .. 287 311 .. 275 312 .. 0.87 2 ! 20.8 0.2 3.2e-05 0.0026 13 38 .] 329 354 .. 321 354 .. 0.90 3 ? 8.2 0.0 0.29 23 8 25 .. 365 386 .. 358 395 .. 0.66 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 0.0077 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 + +afspdg+ la+ s Dg +r++ tr|G5E9A7|G5E9A7_HUMAN 287 LNEFAFSPDGRHLACVSQDGCLRVF 311 57789********988*******97 PP == domain 2 score: 20.8 bits; conditional E-value: 3.2e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ tr|G5E9A7|G5E9A7_HUMAN 329 LLCVCWSPDGRYVVTGGEDDLVTVWS 354 56***********************5 PP == domain 3 score: 8.2 bits; conditional E-value: 0.29 ESS.SSEEEEEEETTSSE...E CS WD40 8 tGH.ssvtslafspdgaw...l 25 GH s+v+++af+p+ + tr|G5E9A7|G5E9A7_HUMAN 365 HGHkSWVNAVAFDPYTTRaeeA 386 488777********99875542 PP >> sp|P78406|RAE1L_HUMAN mRNA export factor OS=Homo sapiens GN=RAE1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.2 3e-05 0.0025 10 38 .] 85 114 .. 79 114 .. 0.91 2 ! 15.8 0.2 0.0012 0.098 19 38 .] 138 157 .. 119 157 .. 0.72 3 ? 12.0 0.2 0.019 1.6 6 38 .] 256 301 .. 252 301 .. 0.78 4 ? 4.4 0.1 4.7 3.8e+02 12 31 .. 317 337 .. 306 339 .. 0.80 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 3e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H ++v ++++s+dg+ ++++s D+t ++Wd sp|P78406|RAE1L_HUMAN 85 HtGPVLDVCWSDDGSKVFTASCDKTAKMWD 114 7667*************99988*******9 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0012 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 p+ + +++Gs+D+t+++Wd sp|P78406|RAE1L_HUMAN 138 APNYSCVMTGSWDKTLKFWD 157 35555599***********9 PP == domain 3 score: 12.0 bits; conditional E-value: 0.019 EEESS.SS............EEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 6 tltGH.ss............vtslafspdgawlas.GsdDgtvriWd 38 t++ H s+ v+++af+p + la+ Gs Dg +Wd sp|P78406|RAE1L_HUMAN 256 TFKCHrSNgtntsapqdiyaVNGIAFHPVHGTLATvGS-DGRFSFWD 301 5666663336667778888899***********96267.*******9 PP == domain 4 score: 4.4 bits; conditional E-value: 4.7 SEEEEEEETTSSEEE.EEETT CS WD40 12 svtslafspdgawla.sGsdD 31 ++++++f+++g+ +a ++s+D sp|P78406|RAE1L_HUMAN 317 PISACCFNHNGNIFAyASSYD 337 5999*********98777777 PP >> sp|Q09019|DMWD_HUMAN Dystrophia myotonica WD repeat-containing protein OS=Homo sapiens GN=DMWD PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.0 0.008 0.65 13 37 .. 287 311 .. 275 312 .. 0.87 2 ! 20.7 0.2 3.3e-05 0.0027 13 38 .] 329 354 .. 321 354 .. 0.90 3 ? 8.2 0.0 0.3 24 8 25 .. 365 386 .. 358 395 .. 0.66 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 0.008 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 + +afspdg+ la+ s Dg +r++ sp|Q09019|DMWD_HUMAN 287 LNEFAFSPDGRHLACVSQDGCLRVF 311 57789********988*******97 PP == domain 2 score: 20.7 bits; conditional E-value: 3.3e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ sp|Q09019|DMWD_HUMAN 329 LLCVCWSPDGRYVVTGGEDDLVTVWS 354 56***********************5 PP == domain 3 score: 8.2 bits; conditional E-value: 0.3 ESS.SSEEEEEEETTSSE...E CS WD40 8 tGH.ssvtslafspdgaw...l 25 GH s+v+++af+p+ + sp|Q09019|DMWD_HUMAN 365 HGHkSWVNAVAFDPYTTRaeeA 386 488777********99875542 PP >> sp|Q3MJ13|WDR72_HUMAN WD repeat-containing protein 72 OS=Homo sapiens GN=WDR72 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.0 0.7 56 10 38 .] 18 45 .. 12 45 .. 0.92 2 ? 8.9 0.0 0.18 15 9 38 .] 60 93 .. 49 93 .. 0.85 3 ! 13.0 0.5 0.0089 0.72 5 38 .] 455 495 .. 452 495 .. 0.88 4 ! 14.0 0.1 0.0045 0.37 2 37 .. 548 584 .. 547 585 .. 0.90 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.7 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 H s+t++ +d++ +++Gs g + +W+ sp|Q3MJ13|WDR72_HUMAN 18 H-SITAIMITDDQRTIVTGSQEGQLCLWN 45 6.79999999******************8 PP == domain 2 score: 8.9 bits; conditional E-value: 0.18 SS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriWd 38 GH svt+la + +++++s+ ++g +W+ sp|Q3MJ13|WDR72_HUMAN 60 GHsASVTCLArarDFSKQPYIVSAAENGEMCVWN 93 9*777********6667777889999*******8 PP == domain 3 score: 13.0 bits; conditional E-value: 0.0089 EEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtsla......fspdgawlasGsdDgtvriWd 38 ++l+GH +svtsl d++w++sG+ D v +Wd sp|Q3MJ13|WDR72_HUMAN 455 KVLKGHhQSVTSLLyphglsSKLDQSWMLSGDLDSCVILWD 495 6799**999*98887777779999999****99*******9 PP == domain 4 score: 14.0 bits; conditional E-value: 0.0045 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +cl + + H ++v+ ++++p ++l+ G+ D +v+iW sp|Q3MJ13|WDR72_HUMAN 548 SCLLHARKHlFPVRMIKWHPVENFLIVGCADDSVYIW 584 577777889999****************99******* PP >> tr|H0YKE0|H0YKE0_HUMAN WD repeat-containing protein 72 OS=Homo sapiens GN=WDR72 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.0 0.7 57 10 38 .] 18 45 .. 12 45 .. 0.92 2 ? 8.9 0.0 0.18 15 9 38 .] 60 93 .. 49 93 .. 0.85 3 ! 13.0 0.5 0.009 0.73 5 38 .] 465 505 .. 462 505 .. 0.88 4 ! 13.9 0.1 0.0046 0.37 2 37 .. 558 594 .. 557 595 .. 0.90 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.7 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 H s+t++ +d++ +++Gs g + +W+ tr|H0YKE0|H0YKE0_HUMAN 18 H-SITAIMITDDQRTIVTGSQEGQLCLWN 45 6.79999999******************8 PP == domain 2 score: 8.9 bits; conditional E-value: 0.18 SS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriWd 38 GH svt+la + +++++s+ ++g +W+ tr|H0YKE0|H0YKE0_HUMAN 60 GHsASVTCLArarDFSKQPYIVSAAENGEMCVWN 93 9*777********6667777889999*******8 PP == domain 3 score: 13.0 bits; conditional E-value: 0.009 EEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtsla......fspdgawlasGsdDgtvriWd 38 ++l+GH +svtsl d++w++sG+ D v +Wd tr|H0YKE0|H0YKE0_HUMAN 465 KVLKGHhQSVTSLLyphglsSKLDQSWMLSGDLDSCVILWD 505 6799**999*98887777779999999****99*******9 PP == domain 4 score: 13.9 bits; conditional E-value: 0.0046 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +cl + + H ++v+ ++++p ++l+ G+ D +v+iW tr|H0YKE0|H0YKE0_HUMAN 558 SCLLHARKHlFPVRMIKWHPVENFLIVGCADDSVYIW 594 577777889999****************99******* PP >> sp|B1ANS9-2|WDR64_HUMAN Isoform 2 of WD repeat-containing protein 64 OS=Homo sapiens GN=WDR64 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.026 2.1 13 37 .. 330 350 .. 316 351 .. 0.75 2 ! 18.0 0.0 0.00024 0.02 6 38 .] 493 528 .. 488 528 .. 0.85 3 ? 7.7 0.0 0.41 33 4 37 .. 693 727 .. 690 728 .. 0.69 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.026 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ + +++G+dD+ +r+W sp|B1ANS9-2|WDR64_HUMAN 330 CYCV----KANVIVTGGDDKVIRLW 350 5566....778899*********** PP == domain 2 score: 18.0 bits; conditional E-value: 0.00024 EEESS.SS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ss..vtslafspdgawlasGsdDgtvriWd 38 +l+ H ++ vts a++ +g ++a+G ++gtvriWd sp|B1ANS9-2|WDR64_HUMAN 493 ILEPHgFNteVTSAAVDESGFLFATGAYNGTVRIWD 528 5677862258****************99*******9 PP == domain 3 score: 7.7 bits; conditional E-value: 0.41 EEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss..vtslafspdgawlasGsdDgtvriW 37 l ++++H s + + + +++ ++++s Dg+vr+W sp|B1ANS9-2|WDR64_HUMAN 693 LLSWRAH-SleIIQVIYVEEKQVVLTASIDGSVRLW 727 5666777.33444665555666689*********** PP >> sp|Q58WW2-4|DCAF6_HUMAN Isoform 4 of DDB1- and CUL4-associated factor 6 OS=Homo sapiens GN=DCAF6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.0 0.6 48 8 38 .] 107 139 .. 101 139 .. 0.60 2 ? 5.3 0.0 2.5 2e+02 24 38 .] 175 189 .. 162 189 .. 0.78 3 ? 4.6 0.0 4 3.2e+02 9 32 .. 216 244 .. 210 250 .. 0.71 4 ? 10.3 0.1 0.064 5.2 6 38 .] 772 807 .. 769 807 .. 0.77 5 ! 14.7 0.0 0.0025 0.21 11 38 .] 821 849 .. 812 849 .. 0.87 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.6 ESS.SS...EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 8 tGH.ss...vtslafspdgaw.lasGsdDgtvriWd 38 t H + + + p+ ++ ++s+++Dgtvr +d sp|Q58WW2-4|DCAF6_HUMAN 107 TCHyGTtyeIMTV---PNDPYtFLSCGEDGTVRWFD 139 4665334567777...333333558999*****776 PP == domain 2 score: 5.3 bits; conditional E-value: 2.5 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +la G+ D +vri+d sp|Q58WW2-4|DCAF6_HUMAN 175 YLAVGCSDSSVRIYD 189 6888866*******8 PP == domain 3 score: 4.6 bits; conditional E-value: 4 SS.SS....EEEEEEETTSSEEEEE.ETTS CS WD40 9 GH.ss....vtslafspdgawlasG.sdDg 32 H ++ vtsl++s dg+ ++ + s sp|Q58WW2-4|DCAF6_HUMAN 216 SHlNNkscrVTSLCYSEDGQEILVSyS-SD 244 577444578***********9887644.44 PP == domain 4 score: 10.3 bits; conditional E-value: 0.064 EEESS.SS........EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ss........vtslafspdgawlasGsdDgtvriWd 38 +++GH +s ++ ++++sGsd g++ iWd sp|Q58WW2-4|DCAF6_HUMAN 772 VYKGHrNSrtmikeanFWGA------NFVMSGSDCGHIFIWD 807 68999988888444443455......889************9 PP == domain 5 score: 14.7 bits; conditional E-value: 0.0025 SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ss.vtslafspdgawlasGsdDgtvriWd 38 ++ v++l+ +p + las++ D ++iW+ sp|Q58WW2-4|DCAF6_HUMAN 821 NHvVNCLQPHPFDPILASSGIDYDIKIWS 849 4546************************5 PP >> tr|C9JGR9|C9JGR9_HUMAN WD repeat-containing protein 37 (Fragment) OS=Homo sapiens GN=WDR37 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.1 0.00039 0.032 2 38 .] 114 152 .. 113 152 .. 0.91 2 ! 28.3 0.1 1.3e-07 1.1e-05 1 37 [. 156 193 .. 156 194 .. 0.92 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 0.00039 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 q+++++ GH ++++++++ + ++ ++ ++s D+t +W+ tr|C9JGR9|C9JGR9_HUMAN 114 QLVKEYIGHrDGIWDVSVAKTQPVVLgTASADHTALLWS 152 7899*****999*************976789*******5 PP == domain 2 score: 28.3 bits; conditional E-value: 1.3e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+cl ++ GH +sv+s++f+p+ ++ +++s D+t +iW tr|C9JGR9|C9JGR9_HUMAN 156 GKCLVKYAGHvGSVNSIKFHPSEQLALTASGDQTAHIW 193 79********999************887766******* PP >> tr|F2Z305|F2Z305_HUMAN DDB1- and CUL4-associated factor 6 OS=Homo sapiens GN=DCAF6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.1 0.00031 0.025 5 35 .. 45 76 .. 41 77 .. 0.86 2 ? 3.9 0.0 6.6 5.3e+02 7 34 .. 90 120 .. 83 121 .. 0.63 3 ? 8.3 0.0 0.27 22 7 38 .] 137 170 .. 132 170 .. 0.60 4 ? 6.4 0.0 1.1 91 24 38 .] 206 220 .. 192 220 .. 0.78 5 ? 5.7 0.0 1.8 1.4e+02 9 33 .. 247 276 .. 241 281 .. 0.72 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 0.00031 EEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvr 35 tl H ++v+ +++++ g +++sGsdD ++ tr|F2Z305|F2Z305_HUMAN 45 ATLNVHdGCVNTICWNDTGEYILSGSDDTKLV 76 68889*777*****************998876 PP == domain 2 score: 3.9 bits; conditional E-value: 6.6 EESS.SSEEEEE..EETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtsla..fspdgawlasGsdDgtv 34 +GH ++ s + + + + ++s+s Dg + tr|F2Z305|F2Z305_HUMAN 90 RSGHrANIFSAKflPCTNDKQIVSCSGDGVI 120 3599888999986633333336677669987 PP == domain 3 score: 8.3 bits; conditional E-value: 0.27 EESS.SS...EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgaw.lasGsdDgtvriWd 38 +t H + + + p+ ++ ++s+++Dgtvr +d tr|F2Z305|F2Z305_HUMAN 137 FTCHyGTtyeIMTV---PNDPYtFLSCGEDGTVRWFD 170 34665334567777...333333558999*****776 PP == domain 4 score: 6.4 bits; conditional E-value: 1.1 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +la G+ D +vri+d tr|F2Z305|F2Z305_HUMAN 206 YLAVGCSDSSVRIYD 220 6888866*******8 PP == domain 5 score: 5.7 bits; conditional E-value: 1.8 SS.SS....EEEEEEETTSSEEEEE.ETTSE CS WD40 9 GH.ss....vtslafspdgawlasG.sdDgt 33 H ++ vtsl++s dg+ ++ + s tr|F2Z305|F2Z305_HUMAN 247 SHlNNkscrVTSLCYSEDGQEILVSyS-SDY 276 577444578***********9887644.444 PP >> tr|M0QX71|M0QX71_HUMAN Glutamate-rich WD repeat-containing protein 1 (Fragment) OS=Homo sapiens GN=GRWD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 3.2 2.6e+02 2 37 .. 102 139 .. 101 140 .. 0.65 2 ! 27.4 0.1 2.6e-07 2.1e-05 4 38 .] 151 187 .. 149 187 .. 0.89 3 ! 13.4 0.1 0.0069 0.56 6 32 .. 200 227 .. 195 228 .] 0.87 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 3.2 EEEEEEESS..SSEEEEEEETTSSE.......EEEEETTSEEEEE CS WD40 2 qclrtltGH..ssvtslafspdgaw.......lasGsdDgtvriW 37 +++ ++ GH + +l +w l++G+ +++++W tr|M0QX71|M0QX71_HUMAN 102 KPIFSFAGHmgEGF-AL------DWsprvtgrLLTGDCQKNIHLW 139 57778888974333.55......333333335779*77******* PP == domain 2 score: 27.4 bits; conditional E-value: 2.6e-07 EEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 +r + GH sv +l++sp + + as+s D ++riWd tr|M0QX71|M0QX71_HUMAN 151 QRPFVGHtRSVEDLQWSPTENTVfASCSADASIRIWD 187 67899**777************8468999*******9 PP == domain 3 score: 13.4 bits; conditional E-value: 0.0069 EEESS.SSEEEEEEETTSSEEEEEETTS CS WD40 6 tltGH.ssvtslafspdgawlasGsdDg 32 t t+H ++v+ +++s+ ++l+sG+dDg tr|M0QX71|M0QX71_HUMAN 200 TATAHdGDVNVISWSRREPFLLSGGDDG 227 4579*888*****************998 PP >> sp|O15143|ARC1B_HUMAN Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens GN=ARPC1B PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.2 3.4e-06 0.00028 2 37 .. 43 79 .. 42 80 .. 0.91 2 ! 16.8 0.3 0.00056 0.045 12 37 .. 144 169 .. 132 170 .. 0.81 3 ? 6.5 1.0 1 84 11 36 .. 203 228 .. 193 230 .. 0.82 4 ? 3.4 0.1 9.5 7.7e+02 21 38 .] 342 358 .. 323 358 .. 0.63 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 3.4e-06 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +++++l+ H++ vt++++ p+++ +++++ D++ ++W sp|O15143|ARC1B_HUMAN 43 TKVHELKEHNGqVTGIDWAPESNRIVTCGTDRNAYVW 79 689******555**************9999******* PP == domain 2 score: 16.8 bits; conditional E-value: 0.00056 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 v sl+++p++ +la+Gs D ++ri+ sp|O15143|ARC1B_HUMAN 144 TVLSLDWHPNNVLLAAGSCDFKCRIF 169 289**************99*****97 PP == domain 3 score: 6.5 bits; conditional E-value: 1 SSEEEEEEETTSSEEE.EEETTSEEEE CS WD40 11 ssvtslafspdgawla.sGsdDgtvri 36 ++v++++fs +g+ +a ++ D tv + sp|O15143|ARC1B_HUMAN 203 GWVHGVCFSASGSRVAwVSH-DSTVCL 228 349***********988889.***986 PP == domain 4 score: 3.4 bits; conditional E-value: 9.5 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +++ ++G+ Dg iWd sp|O15143|ARC1B_HUMAN 342 CSQFCTTGM-DGGMSIWD 358 344555666.*******9 PP >> sp|Q562E7|WDR81_HUMAN WD repeat-containing protein 81 OS=Homo sapiens GN=WDR81 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 0.0 6.5e-07 5.2e-05 4 37 .. 1641 1675 .. 1639 1675 .. 0.92 2 ? 4.7 0.0 3.8 3.1e+02 6 38 .] 1692 1723 .. 1688 1723 .. 0.68 3 ? 6.1 0.2 1.4 1.1e+02 7 38 .] 1824 1855 .. 1818 1855 .. 0.75 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 6.5e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l+++ GH + v ++a ++ ++++sGs+D+tvr+W sp|Q562E7|WDR81_HUMAN 1641 LQSFPGHsGAVKCVAPLSSEDFFLSGSKDRTVRLW 1675 6899***555************************* PP == domain 2 score: 4.7 bits; conditional E-value: 3.8 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 ++t H +sv + g++ ++ ++ Dg v++Wd sp|Q562E7|WDR81_HUMAN 1692 VYTQHrKSVFFV-----GQLeapqHVVSC-DGAVHVWD 1723 677888886555.....444444455578.*******9 PP == domain 3 score: 6.1 bits; conditional E-value: 1.4 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 + +H ++ + ++ +g+ l+s+s D+++ +W+ sp|Q562E7|WDR81_HUMAN 1824 WPAHeGDilqIKAV----EGSVLVSSSSDHSLTVWK 1855 56786666666777....7888998877*******6 PP >> sp|Q8TBZ3-4|WDR20_HUMAN Isoform 4 of WD repeat-containing protein 20 OS=Homo sapiens GN=WDR20 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 0.0013 0.11 13 38 .] 153 178 .. 140 178 .. 0.85 2 ! 22.1 0.2 1.2e-05 0.00099 13 38 .] 195 220 .. 183 220 .. 0.84 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 0.0013 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +afspdg++la+ s Dg +r+++ sp|Q8TBZ3-4|WDR20_HUMAN 153 LNEFAFSPDGKFLACVSQDGFLRVFN 178 67789********988********97 PP == domain 2 score: 22.1 bits; conditional E-value: 1.2e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ sp|Q8TBZ3-4|WDR20_HUMAN 195 LLCVCWSPDGKYIVTGGEDDLVTVWS 220 67***********************5 PP >> tr|H0YLU1|H0YLU1_HUMAN Guanine nucleotide-binding protein subunit beta-5 (Fragment) OS=Homo sapiens GN=GNB5 PE=2 SV= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.1 0.024 2 13 38 .] 13 38 .. 4 38 .. 0.64 2 ! 26.9 0.1 3.7e-07 3e-05 1 38 [] 42 82 .. 42 82 .. 0.91 3 ? 7.7 0.0 0.44 35 1 16 [. 86 102 .. 86 103 .] 0.94 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.024 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++f + ++++s Dgt+ +Wd tr|H0YLU1|H0YLU1_HUMAN 13 LSACSFTNSDMQILTASGDGTCALWD 38 555554444444555544*******9 PP == domain 2 score: 26.9 bits; conditional E-value: 3.7e-07 TEEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 gq+l+++ GH +v +l+ s g+ ++sG+ D++ ++Wd tr|H0YLU1|H0YLU1_HUMAN 42 GQLLQSFHGHgADVLCLDlaPSETGNTFVSGGCDKKAMVWD 82 689*******888988888899999999***88*******9 PP == domain 3 score: 7.7 bits; conditional E-value: 0.44 TEEEEEEESS.SSEEEE CS WD40 1 gqclrtltGH.ssvtsl 16 gqc++ +++H s+++s+ tr|H0YLU1|H0YLU1_HUMAN 86 GQCVQAFETHeSDINSV 102 79********999***9 PP >> sp|Q8TBZ3-5|WDR20_HUMAN Isoform 5 of WD repeat-containing protein 20 OS=Homo sapiens GN=WDR20 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 0.0013 0.11 13 38 .] 162 187 .. 149 187 .. 0.85 2 ! 22.0 0.2 1.2e-05 0.001 13 38 .] 204 229 .. 192 229 .. 0.84 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 0.0013 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +afspdg++la+ s Dg +r+++ sp|Q8TBZ3-5|WDR20_HUMAN 162 LNEFAFSPDGKFLACVSQDGFLRVFN 187 67789********988********97 PP == domain 2 score: 22.0 bits; conditional E-value: 1.2e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ sp|Q8TBZ3-5|WDR20_HUMAN 204 LLCVCWSPDGKYIVTGGEDDLVTVWS 229 67***********************5 PP >> tr|I3L4T9|I3L4T9_HUMAN Cirhin (Fragment) OS=Homo sapiens GN=CIRH1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 0.012 0.96 11 38 .] 28 55 .. 18 55 .. 0.88 2 ! 15.6 0.0 0.0014 0.11 12 37 .. 114 139 .. 106 140 .. 0.89 3 ? 11.9 0.0 0.02 1.6 11 31 .. 157 177 .. 147 179 .. 0.80 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.012 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++++++a++ ++ la + Dgtv i++ tr|I3L4T9|I3L4T9_HUMAN 28 NGIRCVAYNNQSNRLAVSRTDGTVEIYN 55 569************99967******97 PP == domain 2 score: 15.6 bits; conditional E-value: 0.0014 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +++s+a sp+g+ l+ G++Dg+v+++ tr|I3L4T9|I3L4T9_HUMAN 114 PIWSMAASPSGSQLLVGCEDGSVKLF 139 59**********************97 PP == domain 3 score: 11.9 bits; conditional E-value: 0.02 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 s + sl+++p+g+ +a+Gs D tr|I3L4T9|I3L4T9_HUMAN 157 SRILSLSWHPSGTHIAAGSID 177 4499**************966 PP >> tr|E9PQ57|E9PQ57_HUMAN mRNA export factor OS=Homo sapiens GN=RAE1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.2 3.8e-05 0.0031 10 38 .] 85 114 .. 79 114 .. 0.91 2 ! 15.5 0.2 0.0015 0.12 19 38 .] 138 157 .. 119 157 .. 0.72 3 ? 11.6 0.2 0.025 2 6 38 .] 256 301 .. 252 301 .. 0.78 4 ? 4.1 0.1 5.8 4.7e+02 12 31 .. 317 337 .. 306 339 .. 0.80 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 3.8e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H ++v ++++s+dg+ ++++s D+t ++Wd tr|E9PQ57|E9PQ57_HUMAN 85 HtGPVLDVCWSDDGSKVFTASCDKTAKMWD 114 7667*************99988*******9 PP == domain 2 score: 15.5 bits; conditional E-value: 0.0015 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 p+ + +++Gs+D+t+++Wd tr|E9PQ57|E9PQ57_HUMAN 138 APNYSCVMTGSWDKTLKFWD 157 35555599***********9 PP == domain 3 score: 11.6 bits; conditional E-value: 0.025 EEESS.SS............EEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 6 tltGH.ss............vtslafspdgawlas.GsdDgtvriWd 38 t++ H s+ v+++af+p + la+ Gs Dg +Wd tr|E9PQ57|E9PQ57_HUMAN 256 TFKCHrSNgtntsapqdiyaVNGIAFHPVHGTLATvGS-DGRFSFWD 301 5666663336667778888899***********96267.*******9 PP == domain 4 score: 4.1 bits; conditional E-value: 5.8 SEEEEEEETTSSEEE.EEETT CS WD40 12 svtslafspdgawla.sGsdD 31 ++++++f+++g+ +a ++s+D tr|E9PQ57|E9PQ57_HUMAN 317 PISACCFNHNGNIFAyASSYD 337 5999*********98777777 PP >> sp|P57775|FBXW4_HUMAN F-box/WD repeat-containing protein 4 OS=Homo sapiens GN=FBXW4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 0.3 0.11 8.7 2 34 .. 154 185 .. 153 188 .. 0.83 2 ! 18.0 0.1 0.00024 0.019 6 37 .. 197 227 .. 192 227 .. 0.86 3 ? 7.2 1.9 0.61 49 9 38 .] 267 320 .. 235 320 .. 0.57 4 ! 13.6 0.0 0.0058 0.47 3 38 .] 328 365 .. 326 365 .. 0.70 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.11 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtv 34 ++l+++ GH +v+++ + +++ +++G+ Dg++ sp|P57775|FBXW4_HUMAN 154 RPLGVFAGHdEDVCHF-VLANSHIVSAGG-DGKI 185 6899*****888*777.888888899999.**98 PP == domain 2 score: 18.0 bits; conditional E-value: 0.00024 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++H + v+++ + g ++sGs+D+t ++W sp|P57775|FBXW4_HUMAN 197 KYSAHeQEVNCV--DCKGGIIVSGSRDRTAKVW 227 589**888****..66667799*********** PP == domain 3 score: 7.2 bits; conditional E-value: 0.61 SS.SS..EEEEEEETTSSE...........................EEEEETTSEEEEEE CS WD40 9 GH.ss..vtslafspdgaw...........................lasGsdDgtvriWd 38 GH s+ +++l l+s+++D vr Wd sp|P57775|FBXW4_HUMAN 267 GHfSPlrIWDLN------SgqlmthlgsdfppgagvldvmyespftLLSCGYDTYVRYWD 320 443334444443......0333333333334444446666666667677888*******9 PP == domain 4 score: 13.6 bits; conditional E-value: 0.0058 EEEEEE.SS.SSEEEEEEETTSSEE.EEE.ETTSEEEEEE CS WD40 3 clrtlt.GH.ssvtslafspdgawl.asG.sdDgtvriWd 38 c+ +++ H s ++l + dg+ l a+G s+ g vr+Wd sp|P57775|FBXW4_HUMAN 328 CVMEWEePHdSTLYCL--QTDGNHLlATGsSYYGVVRLWD 365 5555543686669999..67777752688568*******9 PP >> sp|Q8TBZ3-6|WDR20_HUMAN Isoform 6 of WD repeat-containing protein 20 OS=Homo sapiens GN=WDR20 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 0.0014 0.11 13 38 .] 162 187 .. 149 187 .. 0.85 2 ! 22.0 0.2 1.3e-05 0.001 13 38 .] 204 229 .. 192 229 .. 0.84 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 0.0014 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +afspdg++la+ s Dg +r+++ sp|Q8TBZ3-6|WDR20_HUMAN 162 LNEFAFSPDGKFLACVSQDGFLRVFN 187 67789********988********97 PP == domain 2 score: 22.0 bits; conditional E-value: 1.3e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ sp|Q8TBZ3-6|WDR20_HUMAN 204 LLCVCWSPDGKYIVTGGEDDLVTVWS 229 67***********************5 PP >> tr|B4DJV5|B4DJV5_HUMAN Periodic tryptophan protein 1 homolog OS=Homo sapiens GN=PWP1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.2 0.002 0.16 7 38 .] 190 223 .. 184 223 .. 0.83 2 ? 10.2 0.0 0.069 5.6 3 38 .] 229 266 .. 227 266 .. 0.82 3 ! 17.8 0.1 0.00027 0.022 2 38 .] 314 352 .. 313 352 .. 0.75 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 0.002 EESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 +GH + v +l +w las+s D+tv +Wd tr|B4DJV5|B4DJV5_HUMAN 190 AEGHtDAVLDL------SWnklirnvLASASADNTVILWD 223 579*6669999......888889998999999*******9 PP == domain 2 score: 10.2 bits; conditional E-value: 0.069 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + +l H + v l+f+p a l+sGs+D++v ++d tr|B4DJV5|B4DJV5_HUMAN 229 PAASLAVHtDKVQTLQFHPFEAQtLISGSYDKSVALYD 266 55677789555999*99999999999********9998 PP == domain 3 score: 17.8 bits; conditional E-value: 0.00027 EEEEEEESSSS.EEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgaw.......lasGsdDgtvriWd 38 +++ tl +H++ +++l+ + l+++s D+ v+iWd tr|B4DJV5|B4DJV5_HUMAN 314 KPIFTLNAHNDeISGLD------LssqikgcLVTASADKYVKIWD 352 678999***66698884......33333444788999*******9 PP >> sp|Q86Y33-2|CD20B_HUMAN Isoform 2 of Cell division cycle protein 20 homolog B OS=Homo sapiens GN=CDC20B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.1 0.33 27 10 38 .] 274 301 .. 259 301 .. 0.86 2 ! 23.5 0.5 4.4e-06 0.00036 4 37 .. 349 382 .. 346 382 .. 0.86 3 ! 17.0 0.3 0.00049 0.04 8 38 .] 482 513 .. 473 513 .. 0.88 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.33 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 ++s+++ ++g+ la G+ g v +Wd sp|Q86Y33-2|CD20B_HUMAN 274 N-YISSVSWIKEGTCLAVGTSEGEVQLWD 301 3.5999*9***********66*******9 PP == domain 2 score: 23.5 bits; conditional E-value: 4.4e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++tl+ H + v++l++spdg++l+sG+ Dg + iW sp|Q86Y33-2|CD20B_HUMAN 349 VGTLR-HkQAVCALKWSPDGRLLSSGCSDGLLTIW 382 56676.9666****************77******9 PP == domain 3 score: 17.0 bits; conditional E-value: 0.00049 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH + v +l+ spd++ ++s+ Dgt +W+ sp|Q86Y33-2|CD20B_HUMAN 482 SGHrGRVLHLSLSPDQTRVFSAAADGTASVWN 513 6**888**************9988*******8 PP >> tr|H0YLX4|H0YLX4_HUMAN WD repeat-containing protein 72 OS=Homo sapiens GN=WDR72 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.0 0.69 56 10 38 .] 18 45 .. 12 45 .. 0.92 2 ? 8.9 0.0 0.18 14 9 38 .] 60 93 .. 49 93 .. 0.85 3 ! 13.0 0.5 0.0088 0.72 5 38 .] 452 492 .. 449 492 .. 0.88 4 ! 14.0 0.1 0.0045 0.36 2 37 .. 545 581 .. 544 582 .. 0.90 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.69 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 H s+t++ +d++ +++Gs g + +W+ tr|H0YLX4|H0YLX4_HUMAN 18 H-SITAIMITDDQRTIVTGSQEGQLCLWN 45 6.79999999******************8 PP == domain 2 score: 8.9 bits; conditional E-value: 0.18 SS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriWd 38 GH svt+la + +++++s+ ++g +W+ tr|H0YLX4|H0YLX4_HUMAN 60 GHsASVTCLArarDFSKQPYIVSAAENGEMCVWN 93 9*777********6667777889999*******8 PP == domain 3 score: 13.0 bits; conditional E-value: 0.0088 EEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtsla......fspdgawlasGsdDgtvriWd 38 ++l+GH +svtsl d++w++sG+ D v +Wd tr|H0YLX4|H0YLX4_HUMAN 452 KVLKGHhQSVTSLLyphglsSKLDQSWMLSGDLDSCVILWD 492 6799**999*98887777779999999****99*******9 PP == domain 4 score: 14.0 bits; conditional E-value: 0.0045 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +cl + + H ++v+ ++++p ++l+ G+ D +v+iW tr|H0YLX4|H0YLX4_HUMAN 545 SCLLHARKHlFPVRMIKWHPVENFLIVGCADDSVYIW 581 577777889999****************99******* PP >> tr|F5H7P7|F5H7P7_HUMAN Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens GN=PPWD1 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.5 0.02 1.6 13 38 .] 63 87 .. 55 87 .. 0.75 2 ! 14.0 0.0 0.0043 0.35 3 38 .] 95 131 .. 93 131 .. 0.88 3 ! 16.1 0.0 0.00091 0.074 14 37 .. 254 277 .. 246 278 .. 0.90 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.02 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 +t++ ++ ++++++s Dg+v++W+ tr|F5H7P7|F5H7P7_HUMAN 63 ITHV-VCTKTDFIITASHDGHVKFWK 87 4555.5556788999999*******6 PP == domain 2 score: 14.0 bits; conditional E-value: 0.0043 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++ H + + s+a+s++ga+++s +dD+ +++d tr|F5H7P7|F5H7P7_HUMAN 95 FVKHFRSHlGVIESIAVSSEGALFCSVGDDKAMKVFD 131 5899****6668************98899***99998 PP == domain 3 score: 16.1 bits; conditional E-value: 0.00091 EEEEEETTSSEEEE.EETTSEEEEE CS WD40 14 tslafspdgawlas.GsdDgtvriW 37 ts++fspdg+ +a+ Gs D++vri+ tr|F5H7P7|F5H7P7_HUMAN 254 TSVCFSPDGKKIATiGS-DRKVRIF 277 89**********95499.*****97 PP >> sp|Q9NZJ0-2|DTL_HUMAN Isoform 2 of Denticleless protein homolog OS=Homo sapiens GN=DTL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.1 0.0017 0.14 2 38 .] 47 84 .. 46 84 .. 0.83 2 ! 24.3 0.1 2.3e-06 0.00019 1 38 [] 88 127 .. 88 127 .. 0.89 3 ? 3.7 0.0 7.6 6.1e+02 12 35 .. 176 199 .. 167 200 .. 0.82 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 0.0017 EEEEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 +c +++ +H + v +la+ p l+++ + D+t ++Wd sp|Q9NZJ0-2|DTL_HUMAN 47 KCFKEWMAHwNAVFDLAWVPGELKLVTAaG-DQTAKFWD 84 68888889*999****87777777887636.*******9 PP == domain 2 score: 24.3 bits; conditional E-value: 2.3e-06 TEEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 g++++t++GH +s s+afs+ + ++ +G++Dg++++Wd sp|Q9NZJ0-2|DTL_HUMAN 88 GELIGTCKGHqCSLKSVAFSKFEKAVFcTGGRDGNIMVWD 127 57899*****999*****999999975499*********9 PP == domain 3 score: 3.7 bits; conditional E-value: 7.6 SEEEEEEETTSSEEEEEETTSEEE CS WD40 12 svtslafspdgawlasGsdDgtvr 35 svt + f+++++++++G Dg + sp|Q9NZJ0-2|DTL_HUMAN 176 SVTVVLFQDENTLVSAGAVDGIFK 199 5777889999999999999*9865 PP >> sp|Q15061|WDR43_HUMAN WD repeat-containing protein 43 OS=Homo sapiens GN=WDR43 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.0 0.35 28 20 37 .. 23 41 .. 12 42 .. 0.66 2 ! 21.1 1.8 2.4e-05 0.002 8 38 .] 123 154 .. 115 154 .. 0.89 3 ! 15.0 0.2 0.0021 0.17 7 37 .. 164 193 .. 157 194 .. 0.84 4 ? 6.3 0.3 1.2 98 5 37 .. 202 249 .. 198 250 .. 0.58 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.35 TTSSE..EEEEETTSEEEEE CS WD40 20 pdgaw..lasGsdDgtvriW 37 p+++ ++++ Dg++r+W sp|Q15061|WDR43_HUMAN 23 PHSQAyfALAST-DGHLRVW 41 333333334677.******* PP == domain 2 score: 21.1 bits; conditional E-value: 2.4e-05 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + v+++++++d+ l s+sdD+++ W+ sp|Q15061|WDR43_HUMAN 123 GGHdNRVNCIQWHQDSGCLYSCSDDKHIVEWN 154 4**888**********************9887 PP == domain 3 score: 15.0 bits; conditional E-value: 0.0021 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++G ssv+sl+ spdg++l+s +t+++W sp|Q15061|WDR43_HUMAN 164 WKGDnSSVSSLCISPDGKMLLS-A-GRTIKLW 193 4577577**************5.7.9****** PP == domain 4 score: 6.3 bits; conditional E-value: 1.2 EEEESS.SSEEEEE......EETTSSE............EEEE..ETTSEEEEE CS WD40 5 rtltGH.ssvtsla......fspdgaw............lasG..sdDgtvriW 37 r++tGH ++v+sl ++sG + D+ + +W sp|Q15061|WDR43_HUMAN 202 RHFTGHaTPVSSLMfttirpP-----NesqpfdgitglyFLSGavH-DRLLNVW 249 899999888888843333331.....02223344445555567444.8888888 PP >> tr|H3BU76|H3BU76_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.2 4.7e-07 3.8e-05 7 37 .. 77 109 .. 72 110 .. 0.86 2 ! 18.6 0.1 0.00016 0.013 2 38 .] 122 160 .. 121 160 .. 0.79 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 4.7e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH +v ++a++p+++ + asGs+D+tv++W tr|H3BU76|H3BU76_HUMAN 77 VCGHtAPVLDIAWCPHNDNViASGSEDCTVMVW 109 559*888************73699********* PP == domain 2 score: 18.6 bits; conditional E-value: 0.00016 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v +a++ + l++G+ D+ +++Wd tr|H3BU76|H3BU76_HUMAN 122 EPVVTLEGHtKRVGIVAWHTTAQNvlLSAGC-DNVIMVWD 160 68899****9889888777777774344677.*******9 PP >> tr|E7EQ49|E7EQ49_HUMAN WD repeat-containing protein 37 OS=Homo sapiens GN=WDR37 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.1 0.00052 0.042 2 38 .] 147 185 .. 146 185 .. 0.91 2 ! 27.9 0.1 1.8e-07 1.4e-05 1 37 [. 189 226 .. 189 227 .. 0.92 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 0.00052 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 q+++++ GH ++++++++ + ++ ++ ++s D+t +W+ tr|E7EQ49|E7EQ49_HUMAN 147 QLVKEYIGHrDGIWDVSVAKTQPVVLgTASADHTALLWS 185 7899*****999*************976789*******5 PP == domain 2 score: 27.9 bits; conditional E-value: 1.8e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+cl ++ GH +sv+s++f+p+ ++ +++s D+t +iW tr|E7EQ49|E7EQ49_HUMAN 189 GKCLVKYAGHvGSVNSIKFHPSEQLALTASGDQTAHIW 226 79********999************887766******* PP >> sp|Q96BP3|PPWD1_HUMAN Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens GN=PPWD1 PE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.5 0.021 1.7 13 38 .] 93 117 .. 85 117 .. 0.75 2 ! 13.9 0.0 0.0045 0.37 3 38 .] 125 161 .. 123 161 .. 0.88 3 ! 16.1 0.0 0.00097 0.078 14 37 .. 284 307 .. 276 308 .. 0.90 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.021 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 +t++ ++ ++++++s Dg+v++W+ sp|Q96BP3|PPWD1_HUMAN 93 ITHV-VCTKTDFIITASHDGHVKFWK 117 4555.5556788999999*******6 PP == domain 2 score: 13.9 bits; conditional E-value: 0.0045 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++ H + + s+a+s++ga+++s +dD+ +++d sp|Q96BP3|PPWD1_HUMAN 125 FVKHFRSHlGVIESIAVSSEGALFCSVGDDKAMKVFD 161 5899****6668************98899***99998 PP == domain 3 score: 16.1 bits; conditional E-value: 0.00097 EEEEEETTSSEEEE.EETTSEEEEE CS WD40 14 tslafspdgawlas.GsdDgtvriW 37 ts++fspdg+ +a+ Gs D++vri+ sp|Q96BP3|PPWD1_HUMAN 284 TSVCFSPDGKKIATiGS-DRKVRIF 307 89**********95499.*****97 PP >> sp|Q13610|PWP1_HUMAN Periodic tryptophan protein 1 homolog OS=Homo sapiens GN=PWP1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.2 0.0024 0.19 7 38 .] 252 285 .. 246 285 .. 0.83 2 ? 10.0 0.0 0.082 6.7 3 38 .] 291 328 .. 289 328 .. 0.82 3 ! 17.6 0.1 0.00032 0.026 2 38 .] 376 414 .. 375 414 .. 0.75 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 0.0024 EESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 +GH + v +l +w las+s D+tv +Wd sp|Q13610|PWP1_HUMAN 252 AEGHtDAVLDL------SWnklirnvLASASADNTVILWD 285 579*6669999......888889998999999*******9 PP == domain 2 score: 10.0 bits; conditional E-value: 0.082 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + +l H + v l+f+p a l+sGs+D++v ++d sp|Q13610|PWP1_HUMAN 291 PAASLAVHtDKVQTLQFHPFEAQtLISGSYDKSVALYD 328 55677789555999*99999999899********9998 PP == domain 3 score: 17.6 bits; conditional E-value: 0.00032 EEEEEEESSSS.EEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgaw.......lasGsdDgtvriWd 38 +++ tl +H++ +++l+ + l+++s D+ v+iWd sp|Q13610|PWP1_HUMAN 376 KPIFTLNAHNDeISGLD------LssqikgcLVTASADKYVKIWD 414 678999***66698884......33333444788999*******9 PP >> tr|B3KPG5|B3KPG5_HUMAN WD repeat-containing protein 20 OS=Homo sapiens GN=WDR20 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 0.00097 0.078 13 38 .] 50 75 .. 37 75 .. 0.85 2 ! 22.5 0.2 9.1e-06 0.00074 13 38 .] 92 117 .. 80 117 .. 0.84 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 0.00097 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +afspdg++la+ s Dg +r+++ tr|B3KPG5|B3KPG5_HUMAN 50 LNEFAFSPDGKFLACVSQDGFLRVFN 75 67789********988********97 PP == domain 2 score: 22.5 bits; conditional E-value: 9.1e-06 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ tr|B3KPG5|B3KPG5_HUMAN 92 LLCVCWSPDGKYIVTGGEDDLVTVWS 117 67***********************5 PP >> tr|K7EML4|K7EML4_HUMAN WD repeat-containing protein 18 (Fragment) OS=Homo sapiens GN=WDR18 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.0 0.24 20 12 37 .. 81 105 .. 71 106 .. 0.81 2 ! 21.8 0.6 1.5e-05 0.0012 2 38 .] 111 148 .. 110 148 .. 0.93 3 ! 13.8 0.2 0.0052 0.42 4 37 .. 164 200 .. 162 201 .. 0.83 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.24 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +vt+l sp+g ++++G ++++W tr|K7EML4|K7EML4_HUMAN 81 PVTCLTASPNGLYVLAGV-AESIHLW 105 5**************886.7777777 PP == domain 2 score: 21.8 bits; conditional E-value: 1.5e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l +l+ H ++v++l+f d++ ++sG++D+ v +W+ tr|K7EML4|K7EML4_HUMAN 111 NLLVILSRHyQDVSCLQFTGDSSHFISGGKDCLVLVWS 148 67888999*99**************************5 PP == domain 3 score: 13.8 bits; conditional E-value: 0.0052 EEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw..lasGsdDgtvriW 37 ++++ H ++t+l g++ +a++s D+tv++W tr|K7EML4|K7EML4_HUMAN 164 RHVWSHHaLPITDLHCGFGGPLarVATSSLDQTVKLW 200 5778888777****98888888878999********* PP >> sp|Q8TBZ3-7|WDR20_HUMAN Isoform 7 of WD repeat-containing protein 20 OS=Homo sapiens GN=WDR20 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 0.0016 0.13 13 38 .] 254 279 .. 241 279 .. 0.85 2 ! 21.8 0.2 1.5e-05 0.0012 13 38 .] 296 321 .. 284 321 .. 0.84 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0016 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +afspdg++la+ s Dg +r+++ sp|Q8TBZ3-7|WDR20_HUMAN 254 LNEFAFSPDGKFLACVSQDGFLRVFN 279 67789********988********97 PP == domain 2 score: 21.8 bits; conditional E-value: 1.5e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ sp|Q8TBZ3-7|WDR20_HUMAN 296 LLCVCWSPDGKYIVTGGEDDLVTVWS 321 67***********************5 PP >> tr|H0YH33|H0YH33_HUMAN Serine-threonine kinase receptor-associated protein (Fragment) OS=Homo sapiens GN=STRAP PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.6 0.0 4.1e-12 3.3e-10 2 37 .. 23 59 .. 22 60 .. 0.93 Alignments for each domain: == domain 1 score: 42.6 bits; conditional E-value: 4.1e-12 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + l +++GH +++++++fspdg + asGs+Dgt+r+W tr|H0YH33|H0YH33_HUMAN 23 EELESYKGHfGPIHCVRFSPDGELYASGSEDGTLRLW 59 67889****888************************* PP >> sp|Q8TBZ3|WDR20_HUMAN WD repeat-containing protein 20 OS=Homo sapiens GN=WDR20 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 0.0015 0.12 13 38 .] 223 248 .. 210 248 .. 0.85 2 ! 21.9 0.2 1.4e-05 0.0012 13 38 .] 265 290 .. 253 290 .. 0.84 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0015 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +afspdg++la+ s Dg +r+++ sp|Q8TBZ3|WDR20_HUMAN 223 LNEFAFSPDGKFLACVSQDGFLRVFN 248 67789********988********97 PP == domain 2 score: 21.9 bits; conditional E-value: 1.4e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ sp|Q8TBZ3|WDR20_HUMAN 265 LLCVCWSPDGKYIVTGGEDDLVTVWS 290 67***********************5 PP >> tr|K7EQT1|K7EQT1_HUMAN Fizzy-related protein homolog OS=Homo sapiens GN=FZR1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.7 0.0065 0.52 10 38 .] 230 257 .. 206 257 .. 0.85 2 ? 9.7 0.0 0.096 7.8 1 34 [. 261 293 .. 261 297 .. 0.84 3 ! 20.1 0.1 5.1e-05 0.0042 5 34 .. 307 340 .. 303 342 .. 0.80 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.0065 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 svts+ +s g+++a G+ +g v iWd tr|K7EQT1|K7EQT1_HUMAN 230 D-SVTSVGWSERGNLVAVGTHKGFVQIWD 257 3.699999***********88*******9 PP == domain 2 score: 9.7 bits; conditional E-value: 0.096 TEEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw....lasGsdDgtv 34 g++l l+GH v +l aw l+sGs+D+ + tr|K7EQT1|K7EQT1_HUMAN 261 GKKLSMLEGHtARVGAL------AWnaeqLSSGSRDRMI 293 5788999***666****......77777799*****988 PP == domain 3 score: 20.1 bits; conditional E-value: 5.1e-05 EEEESS.SSEEEEEEETTSSEEEEEE...TTSEE CS WD40 5 rtltGH.ssvtslafspdgawlasGs...dDgtv 34 r l GH + v++l++s d+++lasG+ +D+++ tr|K7EQT1|K7EQT1_HUMAN 307 RRLQGHrQEVCGLKWSTDHQLLASGGndnKDNHC 340 6799**999****************943336665 PP >> sp|Q8TBZ3-2|WDR20_HUMAN Isoform 2 of WD repeat-containing protein 20 OS=Homo sapiens GN=WDR20 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 0.0016 0.13 13 38 .] 223 248 .. 210 248 .. 0.85 2 ! 21.8 0.2 1.5e-05 0.0012 13 38 .] 265 290 .. 253 290 .. 0.84 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0016 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 + +afspdg++la+ s Dg +r+++ sp|Q8TBZ3-2|WDR20_HUMAN 223 LNEFAFSPDGKFLACVSQDGFLRVFN 248 67789********988********97 PP == domain 2 score: 21.8 bits; conditional E-value: 1.5e-05 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ sp|Q8TBZ3-2|WDR20_HUMAN 265 LLCVCWSPDGKYIVTGGEDDLVTVWS 290 67***********************5 PP >> tr|C9JW18|C9JW18_HUMAN WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens GN=WDHD1 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.8 0.1 1e-08 8.4e-07 3 37 .. 5 40 .. 3 41 .. 0.93 2 ? 11.8 0.4 0.021 1.7 16 38 .] 113 135 .. 95 135 .. 0.83 Alignments for each domain: == domain 1 score: 31.8 bits; conditional E-value: 1e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++t++GH +v sl+f+p +las+s Dg+vr+W tr|C9JW18|C9JW18_HUMAN 5 QQKTFRGHdAPVLSLSFDPKDIFLASASCDGSVRVW 40 689*****888**************9989******* PP == domain 2 score: 11.8 bits; conditional E-value: 0.021 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 + +sp g++la+Gs +g + +W+ tr|C9JW18|C9JW18_HUMAN 113 VTWSPCGQYLAAGSINGLIIVWN 135 55********************8 PP >> tr|F8VSA4|F8VSA4_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1C PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.5 3.8e-07 3.1e-05 7 37 .. 76 108 .. 68 109 .. 0.86 2 ! 17.6 0.1 0.00031 0.025 3 38 .] 122 159 .. 120 159 .. 0.83 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 3.8e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W tr|F8VSA4|F8VSA4_HUMAN 76 VCGHtGPVLDIDWCPHNDQViASGSEDCTVMVW 108 45**888************73699********* PP == domain 2 score: 17.6 bits; conditional E-value: 0.00031 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ + iW+ tr|F8VSA4|F8VSA4_HUMAN 122 PVVILEGHsKRVGIVAWHPTARNVLlsAGC-DNAIIIWN 159 77899***888*9999*******6332677.*******8 PP >> tr|F8VRE9|F8VRE9_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1C PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.5 3.9e-07 3.1e-05 7 37 .. 76 108 .. 68 109 .. 0.86 2 ! 17.6 0.1 0.00031 0.025 3 38 .] 122 159 .. 120 159 .. 0.83 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 3.9e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W tr|F8VRE9|F8VRE9_HUMAN 76 VCGHtGPVLDIDWCPHNDQViASGSEDCTVMVW 108 45**888************73699********* PP == domain 2 score: 17.6 bits; conditional E-value: 0.00031 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ + iW+ tr|F8VRE9|F8VRE9_HUMAN 122 PVVILEGHsKRVGIVAWHPTARNVLlsAGC-DNAIIIWN 159 77899***888*9999*******6332677.*******8 PP >> tr|H3BSL1|H3BSL1_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.2 7.4e-07 6e-05 7 37 .. 113 145 .. 108 146 .. 0.86 2 ! 17.9 0.1 0.00025 0.02 2 38 .] 158 196 .. 157 196 .. 0.79 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 7.4e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH +v ++a++p+++ + asGs+D+tv++W tr|H3BSL1|H3BSL1_HUMAN 113 VCGHtAPVLDIAWCPHNDNViASGSEDCTVMVW 145 559*888************73699********* PP == domain 2 score: 17.9 bits; conditional E-value: 0.00025 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v +a++ + l++G+ D+ +++Wd tr|H3BSL1|H3BSL1_HUMAN 158 EPVVTLEGHtKRVGIVAWHTTAQNvlLSAGC-DNVIMVWD 196 68899****9889888777777774344677.*******9 PP >> tr|F8VTT6|F8VTT6_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1C PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.7 0.5 4.1e-07 3.3e-05 7 37 .. 76 108 .. 68 109 .. 0.86 2 ! 17.5 0.1 0.00033 0.027 3 38 .] 122 159 .. 120 159 .. 0.83 Alignments for each domain: == domain 1 score: 26.7 bits; conditional E-value: 4.1e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W tr|F8VTT6|F8VTT6_HUMAN 76 VCGHtGPVLDIDWCPHNDQViASGSEDCTVMVW 108 45**888************73699********* PP == domain 2 score: 17.5 bits; conditional E-value: 0.00033 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ + iW+ tr|F8VTT6|F8VTT6_HUMAN 122 PVVILEGHsKRVGIVAWHPTARNVLlsAGC-DNAIIIWN 159 77899***888*9999*******6332677.*******8 PP >> tr|C9JVR6|C9JVR6_HUMAN Protein TSSC1 (Fragment) OS=Homo sapiens GN=TSSC1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.2 3.3 2.7e+02 18 38 .] 41 62 .. 6 62 .. 0.82 2 ! 27.2 0.0 2.8e-07 2.3e-05 9 38 .] 75 106 .. 66 106 .. 0.88 3 ? 12.5 0.1 0.013 1 2 34 .. 112 146 .. 111 148 .. 0.76 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 3.3 EETTSSE..EEEEETTSEEEEEE CS WD40 18 fspdgaw..lasGsdDgtvriWd 38 +sp+++ +a++ D t+r Wd tr|C9JVR6|C9JVR6_HUMAN 41 WSPHHNCtqVATAN-DTTLRGWD 62 66666667799999.*****998 PP == domain 2 score: 27.2 bits; conditional E-value: 2.8e-07 SSSS.EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgaw.lasGsdDgtvriWd 38 +H+ v++l+f+p++++ las++dD++v++Wd tr|C9JVR6|C9JVR6_HUMAN 75 AHGQlVRDLDFNPNKQYyLASCGDDCKVKFWD 106 784469***********99************9 PP == domain 3 score: 12.5 bits; conditional E-value: 0.013 EEEEEEESSSS.EEEEEEETTSSEEE.EEETTSEE CS WD40 2 qclrtltGHss.vtslafspdgawla.sGsdDgtv 34 ++++tl+ Hs+ v+ ++++++++ l+ +Gs D v tr|C9JVR6|C9JVR6_HUMAN 112 EPVKTLEEHSHwVWNVRYNHSHDQLVlTGSSDSRV 146 6899*****666*****6666666544**889877 PP >> tr|G3V2V3|G3V2V3_HUMAN Protein NEDD1 (Fragment) OS=Homo sapiens GN=NEDD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.3 0.0006 0.049 7 34 .. 35 67 .. 29 68 .. 0.72 2 ! 13.1 0.0 0.0086 0.7 14 38 .] 88 112 .. 79 112 .. 0.93 3 ! 13.6 0.2 0.006 0.48 5 32 .. 120 148 .. 116 154 .. 0.83 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 0.0006 EESS.SS..EEEEEEETTSSEEEEE..ETTSEE CS WD40 7 ltGH.ss..vtslafspdgawlasG..sdDgtv 34 + H s+ ++s+++s+++++l+++ s D+ v tr|G3V2V3|G3V2V3_HUMAN 35 FNPHtSPhgISSICWSSNNNFLVTAssSGDKIV 67 555754567*************86522348776 PP == domain 2 score: 13.1 bits; conditional E-value: 0.0086 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 t++ ++ + +l+sG+ ++tv iWd tr|G3V2V3|G3V2V3_HUMAN 88 TCVNLNSTSMYLVSGGLNNTVNIWD 112 79999999999*************9 PP == domain 3 score: 13.6 bits; conditional E-value: 0.006 EEEESSSS.EEEEEEETTSSEEEEEETTS CS WD40 5 rtltGHss.vtslafspdgawlasGsdDg 32 r+l+ H++ vt++ ++ + ++asGs g tr|G3V2V3|G3V2V3_HUMAN 120 RSLKDHKDqVTCVTYNWNDCYIASGSLSG 148 78999*555****************9655 PP >> sp|Q86Y33-3|CD20B_HUMAN Isoform 3 of Cell division cycle protein 20 homolog B OS=Homo sapiens GN=CDC20B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.1 0.3 24 10 38 .] 274 301 .. 259 301 .. 0.86 2 ! 23.6 0.5 4e-06 0.00032 4 37 .. 349 382 .. 346 382 .. 0.86 3 ! 15.9 0.1 0.0011 0.089 9 38 .] 445 475 .. 437 475 .. 0.90 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.3 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 ++s+++ ++g+ la G+ g v +Wd sp|Q86Y33-3|CD20B_HUMAN 274 N-YISSVSWIKEGTCLAVGTSEGEVQLWD 301 3.5999*9***********66*******9 PP == domain 2 score: 23.6 bits; conditional E-value: 4e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++tl+ H + v++l++spdg++l+sG+ Dg + iW sp|Q86Y33-3|CD20B_HUMAN 349 VGTLR-HkQAVCALKWSPDGRLLSSGCSDGLLTIW 382 56776.9666****************77******9 PP == domain 3 score: 15.9 bits; conditional E-value: 0.0011 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + v +l+ spd++ ++s+ Dgt +W+ sp|Q86Y33-3|CD20B_HUMAN 445 GHrGRVLHLSLSPDQTRVFSAAADGTASVWN 475 9*888**************9988*******8 PP >> sp|Q96FK6|WDR89_HUMAN WD repeat-containing protein 89 OS=Homo sapiens GN=WDR89 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.1 0.0049 0.4 3 38 .] 62 98 .. 60 98 .. 0.78 2 ! 17.0 0.1 0.00048 0.039 9 38 .] 168 199 .. 159 199 .. 0.82 3 ! 14.2 0.2 0.0038 0.31 6 38 .] 315 349 .. 308 349 .. 0.85 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.0049 EEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 lr+++G + ++++f + + + s++ Dgtv+ Wd sp|Q96FK6|WDR89_HUMAN 62 VLREFSGY-PglLNGVRFANSCDSVYSACTDGTVKCWD 98 57888888.334789988888888887777*******9 PP == domain 2 score: 17.0 bits; conditional E-value: 0.00048 SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +H ++vt ++f+p+++ ++sGs Dg v ++d sp|Q96FK6|WDR89_HUMAN 168 THsDDVTQVRFHPSNPNmVVSGSSDGLVNVFD 199 89666************4469988****9998 PP == domain 3 score: 14.2 bits; conditional E-value: 0.0038 EEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH v+s++++ + l++G++D + +W+ sp|Q96FK6|WDR89_HUMAN 315 SLQgGHaATVRSFCWNVQDDSLLTGGEDAQLLLWK 349 44359*777*************************6 PP >> tr|D6REC9|D6REC9_HUMAN THO complex subunit 3 OS=Homo sapiens GN=THOC3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.0 1.4e-06 0.00011 2 38 .] 30 67 .. 29 67 .. 0.91 2 ! 13.5 0.1 0.0064 0.52 12 33 .. 83 104 .. 72 106 .. 0.81 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 1.4e-06 EEEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 ++++++ +H +++ +++f+p g+++a+Gs D v +Wd tr|D6REC9|D6REC9_HUMAN 30 KPVQSINAHpsNCI-CIKFDPMGKYFATGSADALVSLWD 67 6899999**95558.***********************9 PP == domain 2 score: 13.5 bits; conditional E-value: 0.0064 SEEEEEEETTSSEEEEEETTSE CS WD40 12 svtslafspdgawlasGsdDgt 33 +v+ l+fs+dg++las+s+D+ tr|D6REC9|D6REC9_HUMAN 83 PVRTLSFSHDGKMLASASEDHF 104 389999**************96 PP >> tr|F8VVB7|F8VVB7_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1C PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.5 4.6e-07 3.7e-05 7 37 .. 76 108 .. 68 109 .. 0.86 2 ! 17.4 0.1 0.00037 0.03 3 38 .] 122 159 .. 120 159 .. 0.83 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 4.6e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W tr|F8VVB7|F8VVB7_HUMAN 76 VCGHtGPVLDIDWCPHNDQViASGSEDCTVMVW 108 45**888************73699********* PP == domain 2 score: 17.4 bits; conditional E-value: 0.00037 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ + iW+ tr|F8VVB7|F8VVB7_HUMAN 122 PVVILEGHsKRVGIVAWHPTARNVLlsAGC-DNAIIIWN 159 77899***888*9999*******6332677.*******8 PP >> tr|C9JEE7|C9JEE7_HUMAN WD repeat-containing protein 43 (Fragment) OS=Homo sapiens GN=WDR43 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 1.9 2.7e-06 0.00022 8 38 .] 34 65 .. 25 65 .. 0.88 2 ! 18.0 0.2 0.00024 0.02 7 37 .. 75 104 .. 68 105 .. 0.84 3 ? 6.2 0.0 1.2 1e+02 5 16 .. 113 125 .. 109 129 .. 0.85 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 2.7e-06 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + v+++++++d+ l s+sdD+++ W+ tr|C9JEE7|C9JEE7_HUMAN 34 GGHdNRVNCIQWHQDSGCLYSCSDDKHIVEWN 65 4**888**********************9887 PP == domain 2 score: 18.0 bits; conditional E-value: 0.00024 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++G ssv+sl+ spdg++l+s +t+++W tr|C9JEE7|C9JEE7_HUMAN 75 WKGDnSSVSSLCISPDGKMLLS-A-GRTIKLW 104 4577577**************5.7.9****** PP == domain 3 score: 6.2 bits; conditional E-value: 1.2 EEEESS.SSEEEE CS WD40 5 rtltGH.ssvtsl 16 r++tGH ++v+sl tr|C9JEE7|C9JEE7_HUMAN 113 RHFTGHaTPVSSL 125 89****999**99 PP >> sp|Q86Y33|CD20B_HUMAN Cell division cycle protein 20 homolog B OS=Homo sapiens GN=CDC20B PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.1 0.33 27 10 38 .] 274 301 .. 259 301 .. 0.86 2 ! 23.5 0.5 4.4e-06 0.00036 4 37 .. 349 382 .. 346 382 .. 0.86 3 ! 15.7 0.1 0.0012 0.099 9 38 .] 487 517 .. 479 517 .. 0.90 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.33 SSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriWd 38 ++s+++ ++g+ la G+ g v +Wd sp|Q86Y33|CD20B_HUMAN 274 N-YISSVSWIKEGTCLAVGTSEGEVQLWD 301 3.5999*9***********66*******9 PP == domain 2 score: 23.5 bits; conditional E-value: 4.4e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++tl+ H + v++l++spdg++l+sG+ Dg + iW sp|Q86Y33|CD20B_HUMAN 349 VGTLR-HkQAVCALKWSPDGRLLSSGCSDGLLTIW 382 56676.9666****************77******9 PP == domain 3 score: 15.7 bits; conditional E-value: 0.0012 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 GH + v +l+ spd++ ++s+ Dgt +W+ sp|Q86Y33|CD20B_HUMAN 487 GHrGRVLHLSLSPDQTRVFSAAADGTASVWN 517 9*888**************9988*******8 PP >> sp|Q9HCU5|PREB_HUMAN Prolactin regulatory element-binding protein OS=Homo sapiens GN=PREB PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.0 7.4e-05 0.006 16 38 .] 160 182 .. 144 182 .. 0.90 2 ? 10.8 0.0 0.044 3.5 3 37 .. 188 222 .. 186 223 .. 0.85 3 ? 5.5 0.1 2 1.7e+02 8 28 .. 297 322 .. 290 326 .. 0.71 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 7.4e-05 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 ++f++d+++la+G+ Dg vr+W+ sp|Q9HCU5|PREB_HUMAN 160 VCFNHDNTLLATGGTDGYVRVWK 182 679**********99*******6 PP == domain 2 score: 10.8 bits; conditional E-value: 0.044 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++ ++++H + + +la pdg++++ G D + +W sp|Q9HCU5|PREB_HUMAN 188 KVLEFKAHeGEIEDLALGPDGKLVTVGR-DLKASVW 222 56789***888************98776.9888888 PP == domain 3 score: 5.5 bits; conditional E-value: 2 E.SSSS.EEEEEEETTSSEE....EEE CS WD40 8 t.GHss.vtslafspdgawl....asG 28 + GH v++l++s +g++l ++G sp|Q9HCU5|PREB_HUMAN 297 ScGH-EvVSCLDVSESGTFLglgtVTG 322 3399.647***********74344455 PP >> sp|Q9P2H3|IFT80_HUMAN Intraflagellar transport protein 80 homolog OS=Homo sapiens GN=IFT80 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.1 1.3 1.1e+02 10 38 .] 13 41 .. 5 41 .. 0.81 2 ? 9.5 0.0 0.12 9.4 6 38 .] 101 134 .. 96 134 .. 0.75 3 ? 11.2 0.4 0.034 2.8 6 38 .] 183 216 .. 178 216 .. 0.86 4 ? 12.0 0.0 0.019 1.5 10 29 .. 228 248 .. 219 258 .. 0.78 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 1.3 SSS.EEEEEEETTSSE.....EEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgaw.....lasGsdDgtvriWd 38 H+ v+++ w l s+sdD+ + W+ sp|Q9P2H3|IFT80_HUMAN 13 HQElVSCV------GWttaeeLYSCSDDHQIVKWN 41 64469999......888888889********9997 PP == domain 2 score: 9.5 bits; conditional E-value: 0.12 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + ++H + v + +++ +g+ l++ ++Dg ++iW+ sp|Q9P2H3|IFT80_HUMAN 101 SVEAHcGAVLAGRWNYEGTALVTVGEDGQIKIWS 134 55666444666668888899999999*******5 PP == domain 3 score: 11.2 bits; conditional E-value: 0.034 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++H++ + +++++ +++++s+++D++ ++Wd sp|Q9P2H3|IFT80_HUMAN 183 QWKAHDGiILKVDWNSVNDLILSAGEDCKYKVWD 216 4679955479**99999****************9 PP == domain 4 score: 12.0 bits; conditional E-value: 0.019 S.SSEEEEEEETTSSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGs 29 H ++ts+a+ pdg ++a Gs sp|Q9P2H3|IFT80_HUMAN 228 HeHPITSVAWAPDGELFAVGS 248 4338**************998 PP >> sp|Q92747|ARC1A_HUMAN Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens GN=ARPC1A PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.5 9.3e-06 0.00075 5 38 .] 46 80 .. 42 80 .. 0.88 2 ! 16.1 0.2 0.00094 0.076 12 37 .. 140 169 .. 132 170 .. 0.81 3 ? 8.8 0.9 0.2 16 2 36 .. 193 230 .. 192 232 .. 0.80 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 9.3e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+ H +++t++++ p ++ +++++ D++ ++W+ sp|Q92747|ARC1A_HUMAN 46 HELKEHnGHITGIDWAPKSDRIVTCGADRNAYVWS 80 788888666***************999*******5 PP == domain 2 score: 16.1 bits; conditional E-value: 0.00094 S....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s....vtslafspdgawlasGsdDgtvriW 37 + v sl+++p++ +la+Gs D ++r++ sp|Q92747|ARC1A_HUMAN 140 PirstVLSLDWHPNNVLLAAGSCDFKCRVF 169 3444489**************99*****97 PP == domain 3 score: 8.8 bits; conditional E-value: 0.2 EEEEEEESS.SS..EEEEEEETTSSEEE.EEETTSEEEE CS WD40 2 qclrtltGH.ss..vtslafspdgawla.sGsdDgtvri 36 q++ ++ G ++ v++++fs +g+ la ++ D tv + sp|Q92747|ARC1A_HUMAN 193 QLMSEFGGSgTGgwVHGVSFSASGSRLAwVSH-DSTVSV 230 67778877753346*************98889.**9976 PP >> tr|C9JZN1|C9JZN1_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (Fragment) OS=Homo sapiens G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.4 0.0 5.4e-07 4.4e-05 4 38 .] 48 83 .. 45 83 .. 0.94 2 ! 13.9 0.1 0.0045 0.37 12 37 .. 99 124 .. 86 125 .. 0.84 Alignments for each domain: == domain 1 score: 26.4 bits; conditional E-value: 5.4e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd tr|C9JZN1|C9JZN1_HUMAN 48 RRTLRGHlAKIYAMHWGTDSRLLVSASQDGKLIIWD 83 689****999*************************9 PP == domain 2 score: 13.9 bits; conditional E-value: 0.0045 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +v +a+ p+g+++a+G+ D+ + i+ tr|C9JZN1|C9JZN1_HUMAN 99 WVMTCAYAPSGNFVACGGLDNICSIY 124 488889*****************998 PP >> tr|D6RIW8|D6RIW8_HUMAN WD repeat-containing protein 70 OS=Homo sapiens GN=WDR70 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.1 0.00029 0.023 10 38 .] 180 210 .. 167 210 .. 0.86 2 ? 4.4 0.0 4.9 3.9e+02 4 29 .. 224 250 .. 221 260 .. 0.76 3 ! 15.2 0.0 0.0019 0.15 13 38 .] 334 360 .. 323 360 .. 0.86 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 0.00029 S..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H..ssvtslafspdgawlasGsdDgtvriWd 38 H + v++l +p+ga l++G++D v++Wd tr|D6RIW8|D6RIW8_HUMAN 180 HgtKTVSALGLDPSGARLVTGGYDYDVKFWD 210 54366999999*******************9 PP == domain 2 score: 4.4 bits; conditional E-value: 4.9 EEEEESSSSEEEEEEETTSSE..EEEEE CS WD40 4 lrtltGHssvtslafspdgaw..lasGs 29 l+ ++ H + sl++s g++ ++sGs tr|D6RIW8|D6RIW8_HUMAN 224 LQPCECH-QIKSLQYSNTGDMilVVSGS 250 6667899.8************4435887 PP == domain 3 score: 15.2 bits; conditional E-value: 0.0019 E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 v.tslafspdgawlasGsdDgtvriWd 38 + t + +s+dg+++a+++ +g++ iWd tr|D6RIW8|D6RIW8_HUMAN 334 IpTTCTYSRDGNLIAAACQNGSIQIWD 360 568899********************9 PP >> sp|O75530-2|EED_HUMAN Isoform 2 of Polycomb protein EED OS=Homo sapiens GN=EED # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.0 7.7e-07 6.2e-05 2 38 .] 181 219 .. 180 219 .. 0.89 2 ? 12.2 0.0 0.016 1.3 8 37 .. 233 263 .. 225 264 .. 0.76 3 ? 7.1 1.0 0.68 55 5 38 .] 427 463 .. 424 463 .. 0.82 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 7.7e-07 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 qc++++ GH + ++ l+f+p + l+ s s+D+ +r+W+ sp|O75530-2|EED_HUMAN 181 QCIKHYVGHgNAINELKFHPRDPNLLlSVSKDHALRLWN 219 8********999*****888888864499*********8 PP == domain 2 score: 12.2 bits; conditional E-value: 0.016 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 +GH + v s +++ g ++s+++D+++++W sp|O75530-2|EED_HUMAN 233 EGHrDEVLSADYDLLGEKIMSCGMDHSLKLW 263 699777999955445555899999******* PP == domain 3 score: 7.1 bits; conditional E-value: 0.68 EEEESS.SS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ss..vtslafspdgawlasGsdDgtvriWd 38 +tlt H ++ ++ +fs+d++ l++ +dD ++ Wd sp|O75530-2|EED_HUMAN 427 TTLTHHkCGaaIRQTSFSRDSSILIAVCDDASIWRWD 463 5788885448899999*******998888*9998887 PP >> sp|Q8N5D0-5|WDTC1_HUMAN Isoform 5 of WD and tetratricopeptide repeats protein 1 OS=Homo sapiens GN=WDTC1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.1 1.1e-07 9e-06 6 38 .] 42 75 .. 39 75 .. 0.92 2 ? 7.3 0.1 0.57 46 4 38 .] 83 120 .. 80 120 .. 0.74 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 1.1e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH ++v++l ++ g++lasGsdD++ +Wd sp|Q8N5D0-5|WDTC1_HUMAN 42 ELQGHsGCVNCLEWNEKGDLLASGSDDQHTIVWD 75 689**666*************************9 PP == domain 2 score: 7.3 bits; conditional E-value: 0.57 EEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 l tGH ++ s++ + + l++G D +v++ d sp|Q8N5D0-5|WDTC1_HUMAN 83 LSMHTGHtANIFSVKflPHAGDRILITGAADSKVHVHD 120 45567**777****8765556666889*99***99865 PP >> sp|Q8N5D0-3|WDTC1_HUMAN Isoform 3 of WD and tetratricopeptide repeats protein 1 OS=Homo sapiens GN=WDTC1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.1 1.1e-07 9e-06 6 38 .] 42 75 .. 39 75 .. 0.92 2 ? 7.3 0.1 0.57 46 4 38 .] 83 120 .. 80 120 .. 0.74 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 1.1e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH ++v++l ++ g++lasGsdD++ +Wd sp|Q8N5D0-3|WDTC1_HUMAN 42 ELQGHsGCVNCLEWNEKGDLLASGSDDQHTIVWD 75 689**666*************************9 PP == domain 2 score: 7.3 bits; conditional E-value: 0.57 EEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 l tGH ++ s++ + + l++G D +v++ d sp|Q8N5D0-3|WDTC1_HUMAN 83 LSMHTGHtANIFSVKflPHAGDRILITGAADSKVHVHD 120 45567**777****8765556666889*99***99865 PP >> tr|H0YJS1|H0YJS1_HUMAN Echinoderm microtubule-associated protein-like 5 (Fragment) OS=Homo sapiens GN=EML5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.1 8.2 6.6e+02 9 38 .] 49 85 .. 20 85 .. 0.68 2 ! 29.3 0.2 6.5e-08 5.3e-06 7 38 .] 138 171 .. 133 171 .. 0.89 3 ? 6.0 0.0 1.4 1.2e+02 9 32 .. 183 205 .. 177 209 .. 0.81 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.2 SS.SSEEEEE.EETTSSE....EEEEET......TSEEEEEE CS WD40 9 GH.ssvtsla.fspdgaw....lasGsd......DgtvriWd 38 +H ++v ++ + + +++G++ g v++Wd tr|H0YJS1|H0YJS1_HUMAN 49 AHnGPVFAMYtT-----LrdglIVTGGKerpskeGGAVKLWD 85 564445555222.....2333356898556666799999998 PP == domain 2 score: 29.3 bits; conditional E-value: 6.5e-08 EESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgawlasGsdDgtvriWd 38 GH +++++la++p+ ++++s+ +Dgtvr+Wd tr|H0YJS1|H0YJS1_HUMAN 138 VNGHvdGPIWGLATHPSRDFFLSAAEDGTVRLWD 171 469*9556*************************9 PP == domain 3 score: 6.0 bits; conditional E-value: 1.4 SSSSEEEEEEETTSSEEEEEETTS CS WD40 9 GHssvtslafspdgawlasGsdDg 32 GH + +++sp+g+++a G+++g tr|H0YJS1|H0YJS1_HUMAN 183 GH-AARTVCYSPEGDMVAIGMKNG 205 67.457899*********999776 PP >> sp|Q8NFP9-2|NBEA_HUMAN Isoform 2 of Neurobeachin OS=Homo sapiens GN=NBEA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.1 0.96 77 14 37 .. 259 283 .. 243 284 .. 0.75 2 ! 12.9 0.3 0.0095 0.77 4 37 .. 291 329 .. 288 329 .. 0.78 3 ? 5.0 0.0 3 2.4e+02 5 29 .. 352 377 .. 349 380 .. 0.77 4 ? 10.3 0.0 0.063 5.1 16 37 .. 446 467 .. 428 468 .. 0.89 5 ? 5.8 0.0 1.7 1.4e+02 2 34 .. 473 506 .. 472 510 .. 0.86 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.96 EEEEEETTSSEEE.EEETTSEEEEE CS WD40 14 tslafspdgawla.sGsdDgtvriW 37 +++ + d+++++ +G +D++ r++ sp|Q8NFP9-2|NBEA_HUMAN 259 HCFVVTADNRYILiCGFWDKSFRVY 283 35556779999653888******98 PP == domain 2 score: 12.9 bits; conditional E-value: 0.0095 EEEEESSSS.EEEEE....EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtsla....fspdgawlasGsdDgtvriW 37 +++ GH + vt+la + +++sGs+D t+ +W sp|Q8NFP9-2|NBEA_HUMAN 291 TQIVFGHWDvVTCLArsesYIGGDCYIVSGSRDATLLLW 329 555559*3358***9888877777779************ PP == domain 3 score: 5.0 bits; conditional E-value: 3 EEEESSSS.EEEEEEETTSSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGs 29 +ltGH++ v +++++ + +++sG sp|Q8NFP9-2|NBEA_HUMAN 352 AVLTGHDHeVVCVSVCAELGLVISGA 377 689***55799**8888888888876 PP == domain 4 score: 10.3 bits; conditional E-value: 0.063 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 + s+dg+ l++G+d+g v +W sp|Q8NFP9-2|NBEA_HUMAN 446 ILLSSDGQNLVTGGDNGVVEVW 467 55799***************** PP == domain 5 score: 5.8 bits; conditional E-value: 1.7 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtv 34 ++l+++ G ++++++ s+d++ l++G+ g++ sp|Q8NFP9-2|NBEA_HUMAN 473 KQLYIYPGCdAGIRAMDLSHDQRTLITGMASGSI 506 678899999777****************878887 PP >> tr|B4DU75|B4DU75_HUMAN U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens GN=UTP15 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.0 0.005 0.4 9 38 .] 14 43 .. 7 43 .. 0.89 2 ! 26.5 0.1 5e-07 4e-05 1 37 [. 48 85 .. 48 86 .. 0.93 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.005 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H ++v s+ p+g +l+s++ + v++Wd tr|B4DU75|B4DU75_HUMAN 14 EHgQPVESVLLFPSGGLLVSAG-GRYVKVWD 43 58778*****************.*******9 PP == domain 2 score: 26.5 bits; conditional E-value: 5e-07 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 gq+l +l+ H + vt+l+ s++g+ l+sGs D++v+++ tr|B4DU75|B4DU75_HUMAN 48 GQLLVSLKNHhKTVTCLCLSSSGQRLLSGSLDRKVKVY 85 6788999999899***********************98 PP >> sp|Q9H1Z4|WDR13_HUMAN WD repeat-containing protein 13 OS=Homo sapiens GN=WDR13 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.1 4.7 3.8e+02 5 35 .. 165 198 .. 163 199 .. 0.72 2 ! 19.2 0.1 0.0001 0.0081 4 37 .. 210 244 .. 207 244 .. 0.93 3 ? 4.6 0.0 3.9 3.2e+02 10 38 .] 406 437 .. 394 437 .. 0.75 4 ! 14.1 0.0 0.0042 0.34 5 37 .. 447 480 .. 444 481 .. 0.89 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 4.7 EEEESS.SS.EEEEEEETTSSE.EEEEETTSEEE CS WD40 5 rtltGH.ss.vtslafspdgaw.lasGsdDgtvr 35 ++++ H + v ++f d + la++s Dg++ sp|Q9H1Z4|WDR13_HUMAN 165 HVFDQHvDEaVPRVRFANDDRHrLACCSLDGSIS 198 667778533566777777777778999*****96 PP == domain 2 score: 19.2 bits; conditional E-value: 0.0001 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 lr+l+GH +v+++a+s +++ l+s s D t riW sp|Q9H1Z4|WDR13_HUMAN 210 LRVLRGHtRGVSDFAWSLSNDILVSTSLDATMRIW 244 899****766**************999******** PP == domain 3 score: 4.6 bits; conditional E-value: 3.9 SSSEEEEE....EETTSSEEEEEETTSEEEEEE CS WD40 10 Hssvtsla....fspdgawlasGsdDgtvriWd 38 H +v+s+ + ga +++Gs+D v+++d sp|Q9H1Z4|WDR13_HUMAN 406 H-PVRSIFcplmSFRQGACVVTGSEDMCVHFFD 437 5.5666655555666778899********9987 PP == domain 4 score: 14.1 bits; conditional E-value: 0.0042 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l GH +v +++f+ d ++las++ g v +W sp|Q9H1Z4|WDR13_HUMAN 447 NKLQGHsAPVLDVSFNCDESLLASSDASGMVIVW 480 5689**777**************9988******* PP >> tr|A5PKZ0|A5PKZ0_HUMAN IFT172 protein OS=Homo sapiens GN=IFT172 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.2 0.0 0.0038 0.31 12 38 .] 15 44 .. 3 44 .. 0.77 2 ? 7.5 0.0 0.51 41 13 37 .. 69 93 .. 60 94 .. 0.86 3 ? 5.1 0.2 2.8 2.3e+02 7 34 .. 148 176 .. 142 177 .. 0.80 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 0.0038 S...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvriWd 38 + vt++a+s+++a +a ++ D+ v ++d tr|A5PKZ0|A5PKZ0_HUMAN 15 GaakVTCMAWSQNNAKFAVCTVDRVVLLYD 44 2345***********************998 PP == domain 2 score: 7.5 bits; conditional E-value: 0.51 EEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 13 vtslafspdgawlasG.sdDgtvriW 37 v ++afspd++ +a G + D+ ++++ tr|A5PKZ0|A5PKZ0_HUMAN 69 VKGMAFSPDSTKIAIGqT-DNIIYVY 93 7899************66.****998 PP == domain 3 score: 5.1 bits; conditional E-value: 2.8 EESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtv 34 + G s v sl ++ +g+ ++sG+ Dgt+ tr|A5PKZ0|A5PKZ0_HUMAN 148 IYGTeSYVVSLTTNCSGKGILSGHADGTI 176 446656688999999999999*******9 PP >> tr|E9PF58|E9PF58_HUMAN Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens GN=ARPC1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.5 6.2e-06 0.00051 5 38 .] 46 80 .. 42 80 .. 0.88 2 ! 16.6 0.3 0.00064 0.052 12 37 .. 140 169 .. 132 170 .. 0.81 3 ? 9.3 0.9 0.13 11 2 36 .. 193 230 .. 192 232 .. 0.80 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 6.2e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+ H +++t++++ p ++ +++++ D++ ++W+ tr|E9PF58|E9PF58_HUMAN 46 HELKEHnGHITGIDWAPKSDRIVTCGADRNAYVWS 80 788888666***************999*******5 PP == domain 2 score: 16.6 bits; conditional E-value: 0.00064 S....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s....vtslafspdgawlasGsdDgtvriW 37 + v sl+++p++ +la+Gs D ++r++ tr|E9PF58|E9PF58_HUMAN 140 PirstVLSLDWHPNNVLLAAGSCDFKCRVF 169 3444489**************99*****97 PP == domain 3 score: 9.3 bits; conditional E-value: 0.13 EEEEEEESS.SS..EEEEEEETTSSEEE.EEETTSEEEE CS WD40 2 qclrtltGH.ss..vtslafspdgawla.sGsdDgtvri 36 q++ ++ G ++ v++++fs +g+ la ++ D tv + tr|E9PF58|E9PF58_HUMAN 193 QLMSEFGGSgTGgwVHGVSFSASGSRLAwVSH-DSTVSV 230 67788877753346*************98889.**9976 PP >> tr|D6R922|D6R922_HUMAN WD repeat-containing protein 36 OS=Homo sapiens GN=WDR36 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.3 0.004 0.33 3 37 .. 98 131 .. 96 132 .. 0.89 2 ? 6.1 0.0 1.3 1.1e+02 9 37 .. 275 304 .. 267 304 .. 0.83 3 ? 4.7 0.0 3.8 3.1e+02 9 34 .. 321 348 .. 313 351 .. 0.80 4 ? 7.2 0.1 0.6 49 9 38 .] 481 511 .. 472 511 .. 0.86 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.004 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++t++GH ++ l +p g+ ++s + Dg + iW tr|D6R922|D6R922_HUMAN 98 IVHTFKGHkAEIHFL--QPFGDHIISVDTDGILIIW 131 69******655**99..********9988******* PP == domain 2 score: 6.1 bits; conditional E-value: 1.3 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H + + +l f + ++l++ + D+ +riW tr|D6R922|D6R922_HUMAN 275 AHsTAIAGLTFLHREPLLVTNGADNALRIW 304 79555999999999999998666******* PP == domain 3 score: 4.7 bits; conditional E-value: 3.8 SS.SSEEEEE.EETTSSEEEEEETTSEE CS WD40 9 GH.ssvtsla.fspdgawlasGsdDgtv 34 GH + t ++ + ++g+ ++s+s Dgt+ tr|D6R922|D6R922_HUMAN 321 GHsAPLTNIRyYGQNGQQILSASQDGTL 348 9966688888888899999*******97 PP == domain 4 score: 7.2 bits; conditional E-value: 0.6 SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +H +sv+++a++ +++ +++Gs g +++W+ tr|D6R922|D6R922_HUMAN 481 AHkGSVRGVAVDGLNQLtVTTGS-EGLLKFWN 511 79777****99999999788999.*******8 PP >> tr|G3V4L2|G3V4L2_HUMAN Protein NEDD1 (Fragment) OS=Homo sapiens GN=NEDD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.3 0.00059 0.048 7 34 .. 28 60 .. 22 61 .. 0.72 2 ! 13.1 0.0 0.0085 0.68 14 38 .] 81 105 .. 72 105 .. 0.93 3 ! 13.6 0.2 0.0059 0.48 5 32 .. 113 141 .. 109 147 .. 0.83 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 0.00059 EESS.SS..EEEEEEETTSSEEEEE..ETTSEE CS WD40 7 ltGH.ss..vtslafspdgawlasG..sdDgtv 34 + H s+ ++s+++s+++++l+++ s D+ v tr|G3V4L2|G3V4L2_HUMAN 28 FNPHtSPhgISSICWSSNNNFLVTAssSGDKIV 60 555754567*************86522348776 PP == domain 2 score: 13.1 bits; conditional E-value: 0.0085 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 t++ ++ + +l+sG+ ++tv iWd tr|G3V4L2|G3V4L2_HUMAN 81 TCVNLNSTSMYLVSGGLNNTVNIWD 105 79999999999*************9 PP == domain 3 score: 13.6 bits; conditional E-value: 0.0059 EEEESSSS.EEEEEEETTSSEEEEEETTS CS WD40 5 rtltGHss.vtslafspdgawlasGsdDg 32 r+l+ H++ vt++ ++ + ++asGs g tr|G3V4L2|G3V4L2_HUMAN 113 RSLKDHKDqVTCVTYNWNDCYIASGSLSG 141 78999*555****************9655 PP >> tr|J3KT03|J3KT03_HUMAN WD repeat and SOCS box-containing protein 1 (Fragment) OS=Homo sapiens GN=WSB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 0.031 2.5 17 38 .] 121 163 .. 102 163 .. 0.71 2 ! 27.4 0.0 2.5e-07 2e-05 2 38 .] 168 206 .. 167 206 .. 0.84 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.031 E.....................EETTSSEEEEEETTSEEEEEE CS WD40 17 a.....................fspdgawlasGsdDgtvriWd 38 a f +d+ +la+G +g ++iWd tr|J3KT03|J3KT03_HUMAN 121 AfgssvpekqsrcvniewhrfrFGQDQLLLATGLNNGRIKIWD 163 55555555555555566666668899999****77*******9 PP == domain 2 score: 27.4 bits; conditional E-value: 2.5e-07 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 ++l l H+ v++l f pdg+++ +s+s+D+t+r+Wd tr|J3KT03|J3KT03_HUMAN 168 KLLLNLVDHTEvVRDLTFAPDGSLIlVSASRDKTLRVWD 206 6677788896657***********62589*********9 PP >> tr|C9JPK3|C9JPK3_HUMAN Syntaxin-binding protein 5-like OS=Homo sapiens GN=STXBP5L PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.56 45 21 38 .] 123 139 .. 102 139 .. 0.67 2 ? 6.7 0.0 0.87 70 8 38 .] 205 237 .. 199 237 .. 0.82 3 ? 12.6 0.1 0.012 0.95 12 38 .] 252 278 .. 242 278 .. 0.86 4 ? 10.7 0.3 0.049 3.9 24 38 .] 460 477 .. 406 477 .. 0.82 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.56 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +ga+++++s D t+++W+ tr|C9JPK3|C9JPK3_HUMAN 123 EGALVSASS-DDTLHLWN 139 455565556.*******8 PP == domain 2 score: 6.7 bits; conditional E-value: 0.87 ESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 ++H ++v +l+ ++g++l+ G ++gtv +Wd tr|C9JPK3|C9JPK3_HUMAN 205 KTHpGPVVHLSdsPRDEGKLLI-GYENGTVVFWD 237 6798889999987777777776.**********9 PP == domain 3 score: 12.6 bits; conditional E-value: 0.012 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++++++g+ +++++ Dg++ +W+ tr|C9JPK3|C9JPK3_HUMAN 252 AIHSIDWHHEGKQFMCSHSDGSLTLWN 278 39*************9988*******8 PP == domain 4 score: 10.7 bits; conditional E-value: 0.049 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 + +++G+ Dg++++Wd tr|C9JPK3|C9JPK3_HUMAN 460 YpeiIITGHADGSIKFWD 477 155488***********9 PP >> tr|H3BTU6|H3BTU6_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.1 0.00031 0.025 2 38 .] 81 119 .. 80 119 .. 0.79 2 ! 18.9 0.0 0.00012 0.01 9 36 .. 133 161 .. 126 163 .. 0.89 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 0.00031 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v +a++ + l++G+ D+ +++Wd tr|H3BTU6|H3BTU6_HUMAN 81 EPVVTLEGHtKRVGIVAWHTTAQNvlLSAGC-DNVIMVWD 119 68899****9889888777777774344677.*******9 PP == domain 2 score: 18.9 bits; conditional E-value: 0.00012 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 H + ++s+++s+dg +++++++D+ vri tr|H3BTU6|H3BTU6_HUMAN 133 VHpDTIYSVDWSRDGGLICTSCRDKRVRI 161 68777**************9999*****9 PP >> tr|H0Y9E1|H0Y9E1_HUMAN Intraflagellar transport protein 122 homolog (Fragment) OS=Homo sapiens GN=IFT122 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.0 0.22 18 13 34 .. 2 32 .. 1 34 [. 0.77 2 ! 33.0 0.1 4.2e-09 3.4e-07 2 37 .. 31 67 .. 30 68 .. 0.91 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.22 EEEEEEETTSSE..EEEEET.......TSEE CS WD40 13 vtslafspdgaw..lasGsd.......Dgtv 34 ++++af pdg+ la+Gs+ Dgt+ tr|H0Y9E1|H0Y9E1_HUMAN 2 INDIAFKPDGTQliLAAGSRllvydtsDGTL 32 89**********5446998666666778876 PP == domain 2 score: 33.0 bits; conditional E-value: 4.2e-09 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 ++l+ l+GH++ v+++a+ +dg+ +asGs D++v iW tr|H0Y9E1|H0Y9E1_HUMAN 31 TLLQPLKGHKDtVYCVAYAKDGKRFASGSADKSVIIW 67 67899****555************************* PP >> sp|O75530|EED_HUMAN Polycomb protein EED OS=Homo sapiens GN=EED PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.0 7.2e-07 5.8e-05 2 38 .] 181 219 .. 180 219 .. 0.89 2 ? 12.3 0.0 0.015 1.2 8 37 .. 233 263 .. 225 264 .. 0.76 3 ? 7.1 1.0 0.64 52 5 38 .] 402 438 .. 399 438 .. 0.82 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 7.2e-07 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 qc++++ GH + ++ l+f+p + l+ s s+D+ +r+W+ sp|O75530|EED_HUMAN 181 QCIKHYVGHgNAINELKFHPRDPNLLlSVSKDHALRLWN 219 8********999*****888888864499*********8 PP == domain 2 score: 12.3 bits; conditional E-value: 0.015 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 +GH + v s +++ g ++s+++D+++++W sp|O75530|EED_HUMAN 233 EGHrDEVLSADYDLLGEKIMSCGMDHSLKLW 263 699777999955445555899999******* PP == domain 3 score: 7.1 bits; conditional E-value: 0.64 EEEESS.SS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ss..vtslafspdgawlasGsdDgtvriWd 38 +tlt H ++ ++ +fs+d++ l++ +dD ++ Wd sp|O75530|EED_HUMAN 402 TTLTHHkCGaaIRQTSFSRDSSILIAVCDDASIWRWD 438 5788885448899999*******998888*9998887 PP >> sp|Q00005-6|2ABB_HUMAN Isoform 6 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 1.4 1.1e+02 9 37 .. 10 40 .. 6 41 .. 0.80 2 ? 7.1 0.0 0.68 55 24 38 .] 92 108 .. 59 108 .. 0.67 3 ? 5.6 0.0 2 1.6e+02 9 38 .] 160 189 .. 152 189 .. 0.71 4 ? 4.1 0.0 6 4.9e+02 19 36 .. 222 238 .. 200 240 .. 0.77 5 ? 10.3 0.1 0.066 5.4 11 38 .] 271 297 .. 262 297 .. 0.89 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 1.4 SS.SS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ss.vtslafspdgawlasGsdDgtvriW 37 G + ++ + f++ g +la+G++ g v i+ sp|Q00005-6|2ABB_HUMAN 10 GNkADiISTVEFNHTGELLATGDKGGRVVIF 40 564445799*************988888875 PP == domain 2 score: 7.1 bits; conditional E-value: 0.68 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 l+s D+tv++W+ sp|Q00005-6|2ABB_HUMAN 92 AayfLLSTN-DKTVKLWK 108 344567666.*******6 PP == domain 3 score: 5.6 bits; conditional E-value: 2 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++s+++++d +s++ D + +W+ sp|Q00005-6|2ABB_HUMAN 160 AHtYHINSISVNSDYETYMSAD-DLRINLWN 189 67445****9555555545777.*******8 PP == domain 4 score: 4.1 bits; conditional E-value: 6 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 ++ ++++ s+s +gt+r+ sp|Q00005-6|2ABB_HUMAN 222 HHCNTFVYSSS-KGTIRL 238 44556699999.*****8 PP == domain 5 score: 10.3 bits; conditional E-value: 0.066 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d tv++Wd sp|Q00005-6|2ABB_HUMAN 271 SSISDVKFSHSGRYIMT-RDYLTVKVWD 297 46999***********6.99*******9 PP >> tr|F8W7Q3|F8W7Q3_HUMAN WD repeat-containing protein 48 OS=Homo sapiens GN=WDR48 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 0.0068 0.55 11 38 .] 31 58 .. 24 58 .. 0.89 2 ! 21.2 0.6 2.4e-05 0.0019 7 38 .] 71 103 .. 66 103 .. 0.81 3 ? 5.0 0.0 3.1 2.5e+02 3 16 .. 109 122 .. 107 130 .. 0.79 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.0068 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v++l+ +p + l+++++D +riW+ tr|F8W7Q3|F8W7Q3_HUMAN 31 NGVNALQLDPALNRLFTAGRDSIIRIWS 58 56999999999999*99999*******5 PP == domain 2 score: 21.2 bits; conditional E-value: 2.4e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H ++v+++ + +g+ l+s+s D tv++W+ tr|F8W7Q3|F8W7Q3_HUMAN 71 MEHHtDWVNDIVLCCNGKTLISASSDTTVKVWN 103 566866688777777*****99988*******8 PP == domain 3 score: 5.0 bits; conditional E-value: 3.1 EEEEEESSSSEEEE CS WD40 3 clrtltGHssvtsl 16 c+ tl++H+ v+s+ tr|F8W7Q3|F8W7Q3_HUMAN 109 CMSTLRTHKYVCSI 122 999*****777666 PP >> tr|C9JAJ5|C9JAJ5_HUMAN Putative uncharacterized protein LOC349136 OS=Homo sapiens GN=WDR86 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 0.00085 0.069 5 37 .. 3 50 .. 1 51 [. 0.78 2 ! 19.0 0.5 0.00012 0.0094 2 38 .] 56 93 .. 55 93 .. 0.91 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 0.00085 EEEESS.SSEEEEEEETTSSE................EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw................lasGsdDgtvriW 37 r+++GH ++v la + +w l++Gs Dgt ++W tr|C9JAJ5|C9JAJ5_HUMAN 3 REFRGHrNCVLTLA--YSAPWdlpstpcaeeaaagglLVTGSTDGTAKVW 50 789***99999994..23444666677788888888789*********** PP == domain 2 score: 19.0 bits; conditional E-value: 0.00012 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +tl+GH + v +l + g+ ++Gs D t+r Wd tr|C9JAJ5|C9JAJ5_HUMAN 56 CCHQTLRGHtGAVLCLVLDTPGHTAFTGSTDATIRAWD 93 68899****777*****999999999***********9 PP >> tr|E7EVM5|E7EVM5_HUMAN DDB1- and CUL4-associated factor 13 OS=Homo sapiens GN=DCAF13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 7.5e-06 0.00061 4 38 .] 55 91 .. 53 91 .. 0.82 2 ! 20.2 0.1 4.6e-05 0.0038 1 38 [] 95 133 .. 95 133 .. 0.91 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 7.5e-06 EEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 l +l+GH ++v++la +p++ ++sG Dg vriW+ tr|E7EVM5|E7EVM5_HUMAN 55 LASLDGHrDGVNCLAKHPEKLAtVLSGACDGEVRIWN 91 6789***999****966665556889966*******8 PP == domain 2 score: 20.2 bits; conditional E-value: 4.6e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++c+rt+ +H ++v+++++ g+ +++ +dD+tv+ W+ tr|E7EVM5|E7EVM5_HUMAN 95 RNCIRTIQAHeGFVRGICTRFCGTSFFTVGDDKTVKQWK 133 58********888*****9999999998888*******6 PP >> sp|Q86TI4-2|WDR86_HUMAN Isoform 2 of WD repeat-containing protein 86 OS=Homo sapiens GN=WDR86 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 0.00085 0.069 5 37 .. 3 50 .. 1 51 [. 0.78 2 ! 19.0 0.5 0.00012 0.0094 2 38 .] 56 93 .. 55 93 .. 0.91 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 0.00085 EEEESS.SSEEEEEEETTSSE................EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw................lasGsdDgtvriW 37 r+++GH ++v la + +w l++Gs Dgt ++W sp|Q86TI4-2|WDR86_HUMAN 3 REFRGHrNCVLTLA--YSAPWdlpstpcaeeaaagglLVTGSTDGTAKVW 50 789***99999994..23444666677788888888789*********** PP == domain 2 score: 19.0 bits; conditional E-value: 0.00012 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c +tl+GH + v +l + g+ ++Gs D t+r Wd sp|Q86TI4-2|WDR86_HUMAN 56 CCHQTLRGHtGAVLCLVLDTPGHTAFTGSTDATIRAWD 93 68899****777*****999999999***********9 PP >> sp|Q15291|RBBP5_HUMAN Retinoblastoma-binding protein 5 OS=Homo sapiens GN=RBBP5 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.4 0.056 4.5 18 38 .] 32 52 .. 17 52 .. 0.80 2 ! 21.2 2.0 2.3e-05 0.0019 6 38 .] 61 94 .. 58 94 .. 0.92 3 ? 9.6 0.0 0.11 8.9 16 37 .. 257 279 .. 248 280 .. 0.89 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.056 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 f++ g++la G+ Dg + iWd sp|Q15291|RBBP5_HUMAN 32 FNRWGTLLAVGCNDGRIVIWD 52 8888899*************9 PP == domain 2 score: 21.2 bits; conditional E-value: 2.3e-05 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++H +v+sl++s+dg+ l+s+s D+ v Wd sp|Q15291|RBBP5_HUMAN 61 IISAHiHPVCSLCWSRDGHKLVSASTDNIVSQWD 94 56799889****************99*******9 PP == domain 3 score: 9.6 bits; conditional E-value: 0.11 EEEETTSSEEEEEE.TTSEEEEE CS WD40 16 lafspdgawlasGs.dDgtvriW 37 ++fs dg ++++Gs + + ++iW sp|Q15291|RBBP5_HUMAN 257 CCFSGDGEYIVAGSaRQHALYIW 279 78***********857******* PP >> sp|Q8NHV4-2|NEDD1_HUMAN Isoform 2 of Protein NEDD1 OS=Homo sapiens GN=NEDD1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 1.6 1.3e+02 24 38 .] 2 16 .. 1 16 [. 0.93 2 ? 11.2 0.2 0.034 2.7 5 32 .. 24 52 .. 20 58 .. 0.83 3 ? 7.4 0.2 0.53 43 8 38 .] 68 102 .. 59 102 .. 0.77 4 ? 8.1 0.0 0.31 25 3 38 .] 152 187 .. 150 187 .. 0.79 5 ? 5.5 0.1 2.2 1.8e+02 2 20 .. 193 212 .. 192 228 .. 0.84 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 1.6 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +l+sG+ ++tv iWd sp|Q8NHV4-2|NEDD1_HUMAN 2 YLVSGGLNNTVNIWD 16 689***********9 PP == domain 2 score: 11.2 bits; conditional E-value: 0.034 EEEESSSS.EEEEEEETTSSEEEEEETTS CS WD40 5 rtltGHss.vtslafspdgawlasGsdDg 32 r+l+ H++ vt++ ++ + ++asGs g sp|Q8NHV4-2|NEDD1_HUMAN 24 RSLKDHKDqVTCVTYNWNDCYIASGSLSG 52 68999*555******99********9655 PP == domain 3 score: 7.4 bits; conditional E-value: 0.53 ESS.SS..EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 8 tGH.ss..vtslafspdgawlasG..sdDgtvriWd 38 GH s+ v++l++s ++ l+ G sd+g v +Wd sp|Q8NHV4-2|NEDD1_HUMAN 68 FGHgSNqsVRHLKYSLFKKSLL-GsvSDNGIVTLWD 102 39973367****9998899999.53579*******9 PP == domain 4 score: 8.1 bits; conditional E-value: 0.31 EEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHssvtslafspdgawlasGsdDgtvriWd 38 +++tl + ++ t+++f pdga la Gs g+++ +d sp|Q8NHV4-2|NEDD1_HUMAN 152 LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYD 187 56777666789***************8677776665 PP == domain 5 score: 5.5 bits; conditional E-value: 2.2 EEEEEEESS.SSEEEEEEET CS WD40 2 qclrtltGH.ssvtslafsp 20 ++++t+++H +sv ++af+ sp|Q8NHV4-2|NEDD1_HUMAN 193 SPVKTISAHkTSVQCIAFQY 212 6899*****888****8764 PP >> sp|Q8N5D0-6|WDTC1_HUMAN Isoform 6 of WD and tetratricopeptide repeats protein 1 OS=Homo sapiens GN=WDTC1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.1 1.1e-07 9.3e-06 6 38 .] 42 75 .. 39 75 .. 0.92 2 ? 7.3 0.1 0.59 48 4 38 .] 83 120 .. 80 120 .. 0.74 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 1.1e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH ++v++l ++ g++lasGsdD++ +Wd sp|Q8N5D0-6|WDTC1_HUMAN 42 ELQGHsGCVNCLEWNEKGDLLASGSDDQHTIVWD 75 689**666*************************9 PP == domain 2 score: 7.3 bits; conditional E-value: 0.59 EEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 l tGH ++ s++ + + l++G D +v++ d sp|Q8N5D0-6|WDTC1_HUMAN 83 LSMHTGHtANIFSVKflPHAGDRILITGAADSKVHVHD 120 45567**777****8765556666889*99***99865 PP >> sp|Q8N5D0-2|WDTC1_HUMAN Isoform 2 of WD and tetratricopeptide repeats protein 1 OS=Homo sapiens GN=WDTC1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.1 1.1e-07 9.3e-06 6 38 .] 42 75 .. 39 75 .. 0.92 2 ? 7.2 0.1 0.59 48 4 38 .] 83 120 .. 80 120 .. 0.74 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 1.1e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l GH ++v++l ++ g++lasGsdD++ +Wd sp|Q8N5D0-2|WDTC1_HUMAN 42 ELQGHsGCVNCLEWNEKGDLLASGSDDQHTIVWD 75 689**666*************************9 PP == domain 2 score: 7.2 bits; conditional E-value: 0.59 EEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 l tGH ++ s++ + + l++G D +v++ d sp|Q8N5D0-2|WDTC1_HUMAN 83 LSMHTGHtANIFSVKflPHAGDRILITGAADSKVHVHD 120 45567**777****8765556666889*99***99865 PP >> sp|Q15291-2|RBBP5_HUMAN Isoform 2 of Retinoblastoma-binding protein 5 OS=Homo sapiens GN=RBBP5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.4 0.051 4.1 18 38 .] 32 52 .. 17 52 .. 0.80 2 ! 21.3 2.0 2.1e-05 0.0017 6 38 .] 61 94 .. 58 94 .. 0.92 3 ? 3.4 0.0 9.4 7.7e+02 8 38 .] 193 226 .. 184 226 .. 0.71 4 ? 9.7 0.0 0.1 8.1 16 37 .. 257 279 .. 247 280 .. 0.89 5 ? 3.4 0.1 9.5 7.7e+02 2 37 .. 285 321 .. 284 321 .. 0.81 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.051 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 f++ g++la G+ Dg + iWd sp|Q15291-2|RBBP5_HUMAN 32 FNRWGTLLAVGCNDGRIVIWD 52 8888899*************9 PP == domain 2 score: 21.3 bits; conditional E-value: 2.1e-05 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++H +v+sl++s+dg+ l+s+s D+ v Wd sp|Q15291-2|RBBP5_HUMAN 61 IISAHiHPVCSLCWSRDGHKLVSASTDNIVSQWD 94 56799889****************99*******9 PP == domain 3 score: 3.4 bits; conditional E-value: 9.4 ESS.SS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ss..vtslafspdgawlasGsdDgtvriWd 38 tG + + s+ f + g+ ++ + D+ +r++d sp|Q15291-2|RBBP5_HUMAN 193 TGTsNTtaIKSIEFARKGSCFLINTADRIIRVYD 226 45532256889988888888765555******98 PP == domain 4 score: 9.7 bits; conditional E-value: 0.1 EEEETTSSEEEEEE.TTSEEEEE CS WD40 16 lafspdgawlasGs.dDgtvriW 37 ++fs dg ++++Gs + + ++iW sp|Q15291-2|RBBP5_HUMAN 257 CCFSGDGEYIVAGSaRQHALYIW 279 78***********857******* PP == domain 5 score: 3.4 bits; conditional E-value: 9.5 EEEEEEESS.SS.EEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 2 qclrtltGH.ss.vtslafspdgawlasG.sdDgtvriW 37 +++++l G + ++a++p + +a + s g v iW sp|Q15291-2|RBBP5_HUMAN 285 NLVKILHGTrGElLLDVAWHPVRPIIA-SiS-SGVVSIW 321 678888888666668**********97.559.9999999 PP >> tr|C9JQS3|C9JQS3_HUMAN Syntaxin-binding protein 5-like (Fragment) OS=Homo sapiens GN=STXBP5L PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.64 52 21 38 .] 123 139 .. 102 139 .. 0.67 2 ? 6.5 0.0 1 81 8 38 .] 205 237 .. 199 237 .. 0.82 3 ? 12.4 0.1 0.013 1.1 12 38 .] 252 278 .. 242 278 .. 0.86 4 ? 10.5 0.3 0.055 4.4 24 38 .] 460 477 .. 406 477 .. 0.82 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.64 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +ga+++++s D t+++W+ tr|C9JQS3|C9JQS3_HUMAN 123 EGALVSASS-DDTLHLWN 139 455565556.*******8 PP == domain 2 score: 6.5 bits; conditional E-value: 1 ESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 ++H ++v +l+ ++g++l+ G ++gtv +Wd tr|C9JQS3|C9JQS3_HUMAN 205 KTHpGPVVHLSdsPRDEGKLLI-GYENGTVVFWD 237 6798889999987777777776.**********9 PP == domain 3 score: 12.4 bits; conditional E-value: 0.013 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++++++g+ +++++ Dg++ +W+ tr|C9JQS3|C9JQS3_HUMAN 252 AIHSIDWHHEGKQFMCSHSDGSLTLWN 278 39*************9988*******8 PP == domain 4 score: 10.5 bits; conditional E-value: 0.055 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 + +++G+ Dg++++Wd tr|C9JQS3|C9JQS3_HUMAN 460 YpeiIITGHADGSIKFWD 477 155488***********9 PP >> tr|H7BZA0|H7BZA0_HUMAN Neurobeachin-like protein 1 (Fragment) OS=Homo sapiens GN=NBEAL1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.7 1.9e-05 0.0015 4 37 .. 449 483 .. 446 484 .. 0.85 2 ! 13.7 0.0 0.0056 0.45 2 36 .. 498 533 .. 497 534 .. 0.90 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 1.9e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + ++ H + vt+la++ g l+sGs+D t++iW tr|H7BZA0|H7BZA0_HUMAN 449 ISHIIRHmDIVTCLATDYCGIHLISGSRDTTCMIW 483 55666696669************************ PP == domain 2 score: 13.7 bits; conditional E-value: 0.0056 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++ ++l GH + v s+ s + ++ +sGs+Dgtv i tr|H7BZA0|H7BZA0_HUMAN 498 KPFQILYGHtNEVLSVGISTELDMAVSGSRDGTVII 533 6788999**9889999999999***********976 PP >> sp|Q12770-4|SCAP_HUMAN Isoform 4 of Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sa # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.1 0.022 1.8 6 38 .] 379 410 .. 377 410 .. 0.95 2 ? 10.0 0.0 0.078 6.3 5 37 .. 679 711 .. 675 712 .. 0.72 3 ! 19.3 0.2 9.4e-05 0.0076 2 38 .] 717 753 .. 716 753 .. 0.79 4 ? 6.9 2.0 0.76 62 5 38 .] 762 793 .. 757 793 .. 0.69 5 ? 3.6 0.2 8.6 6.9e+02 23 38 .] 819 833 .. 813 833 .. 0.89 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.022 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH ++ +l +dg +l+s++ g+v +Wd sp|Q12770-4|SCAP_HUMAN 379 VLRGHlMDIECL--ASDGMLLVSCCLAGHVCVWD 410 689**999****..99*****************9 PP == domain 2 score: 10.0 bits; conditional E-value: 0.078 EEEE.SS.SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 5 rtlt.GH.ssvtslafspdgaw....lasGsdDgtvriW 37 +t +H +++t+l + l++Gs D+t+r++ sp|Q12770-4|SCAP_HUMAN 679 HTVPcAHqKPITAL------KAaagrLVTGSQDHTLRVF 711 4543489999**99......333444679********97 PP == domain 3 score: 19.3 bits; conditional E-value: 9.4e-05 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 cl tl GH + +t + d+++ lasG+ Dg + +Wd sp|Q12770-4|SCAP_HUMAN 717 CCLFTLQGHsGAITTV--YIDQTMvLASGGQDGAICLWD 753 599******5559999..3344444689**********9 PP == domain 4 score: 6.9 bits; conditional E-value: 0.76 EEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +++ +H ++vtsl + ++s++ D + iWd sp|Q12770-4|SCAP_HUMAN 762 HVF-AHrGDVTSL------TCttscVISSGLDDLISIWD 793 445.899999999......333343556666*******9 PP == domain 5 score: 3.6 bits; conditional E-value: 8.6 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++l++G+ g v +Wd sp|Q12770-4|SCAP_HUMAN 819 NLLVTGG-QGCVSFWD 833 6799***.*******9 PP >> tr|H0YGZ5|H0YGZ5_HUMAN Pre-mRNA-processing factor 19 (Fragment) OS=Homo sapiens GN=PRPF19 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.1 9.5e-05 0.0077 12 38 .] 24 50 .. 10 50 .. 0.83 2 ! 18.2 0.1 0.00021 0.017 3 37 .. 82 117 .. 80 118 .. 0.89 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 9.5e-05 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 s t+ +f+pdg + +G++D ++iWd tr|H0YGZ5|H0YGZ5_HUMAN 24 SLTCAQFHPDGLIFGTGTMDSQIKIWD 50 589**********879999*******9 PP == domain 2 score: 18.2 bits; conditional E-value: 0.00021 EEEEEESSSSE.EEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGHssv.tslafspdgawlasGsdDgtvriW 37 + ++t Hs+ t++af ++ +++as ++D++++++ tr|H0YGZ5|H0YGZ5_HUMAN 82 EILHFTEHSGLtTGVAFGHHAKFIASTGMDRSLKFY 117 6789****99889***********98888*****98 PP >> sp|Q00005-2|2ABB_HUMAN Isoform 2 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.0 0.39 31 8 37 .. 22 54 .. 15 55 .. 0.79 2 ? 7.0 0.0 0.71 58 24 38 .] 106 122 .. 73 122 .. 0.67 3 ? 5.5 0.0 2.1 1.7e+02 9 38 .] 174 203 .. 166 203 .. 0.71 4 ? 4.0 0.0 6.3 5.1e+02 19 36 .. 236 252 .. 214 254 .. 0.77 5 ? 10.2 0.1 0.069 5.6 11 38 .] 285 311 .. 276 311 .. 0.89 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.39 ESS..SS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH..ss.vtslafspdgawlasGsdDgtvriW 37 + H + ++ + f++ g +la+G++ g v i+ sp|Q00005-2|2ABB_HUMAN 22 SCHteADiISTVEFNHTGELLATGDKGGRVVIF 54 578644467***************988888875 PP == domain 2 score: 7.0 bits; conditional E-value: 0.71 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 l+s D+tv++W+ sp|Q00005-2|2ABB_HUMAN 106 AayfLLSTN-DKTVKLWK 122 344567666.*******6 PP == domain 3 score: 5.5 bits; conditional E-value: 2.1 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++s+++++d +s++ D + +W+ sp|Q00005-2|2ABB_HUMAN 174 AHtYHINSISVNSDYETYMSAD-DLRINLWN 203 67445****9555555545777.*******8 PP == domain 4 score: 4.0 bits; conditional E-value: 6.3 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 ++ ++++ s+s +gt+r+ sp|Q00005-2|2ABB_HUMAN 236 HHCNTFVYSSS-KGTIRL 252 44556699999.*****8 PP == domain 5 score: 10.2 bits; conditional E-value: 0.069 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d tv++Wd sp|Q00005-2|2ABB_HUMAN 285 SSISDVKFSHSGRYIMT-RDYLTVKVWD 311 46999***********6.99*******9 PP >> sp|Q12770-2|SCAP_HUMAN Isoform 2 of Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sa # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 0.023 1.8 6 38 .] 398 429 .. 396 429 .. 0.95 2 ? 10.0 0.0 0.08 6.5 5 37 .. 698 730 .. 694 731 .. 0.72 3 ! 19.2 0.2 9.6e-05 0.0078 2 38 .] 736 772 .. 735 772 .. 0.79 4 ? 6.9 2.0 0.78 63 5 38 .] 781 812 .. 776 812 .. 0.69 5 ? 3.5 0.2 8.8 7.1e+02 23 38 .] 838 852 .. 832 852 .. 0.89 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.023 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH ++ +l +dg +l+s++ g+v +Wd sp|Q12770-2|SCAP_HUMAN 398 VLRGHlMDIECL--ASDGMLLVSCCLAGHVCVWD 429 689**999****..99*****************9 PP == domain 2 score: 10.0 bits; conditional E-value: 0.08 EEEE.SS.SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 5 rtlt.GH.ssvtslafspdgaw....lasGsdDgtvriW 37 +t +H +++t+l + l++Gs D+t+r++ sp|Q12770-2|SCAP_HUMAN 698 HTVPcAHqKPITAL------KAaagrLVTGSQDHTLRVF 730 4543489999**99......333444679********97 PP == domain 3 score: 19.2 bits; conditional E-value: 9.6e-05 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 cl tl GH + +t + d+++ lasG+ Dg + +Wd sp|Q12770-2|SCAP_HUMAN 736 CCLFTLQGHsGAITTV--YIDQTMvLASGGQDGAICLWD 772 599******5559999..3344444689**********9 PP == domain 4 score: 6.9 bits; conditional E-value: 0.78 EEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +++ +H ++vtsl + ++s++ D + iWd sp|Q12770-2|SCAP_HUMAN 781 HVF-AHrGDVTSL------TCttscVISSGLDDLISIWD 812 445.899999999......333343556666*******9 PP == domain 5 score: 3.5 bits; conditional E-value: 8.8 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++l++G+ g v +Wd sp|Q12770-2|SCAP_HUMAN 838 NLLVTGG-QGCVSFWD 852 6799***.*******9 PP >> sp|Q00005|2ABB_HUMAN Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform OS=Homo sapien # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.96 78 9 37 .. 17 51 .. 11 52 .. 0.76 2 ? 7.0 0.0 0.71 57 24 38 .] 103 119 .. 70 119 .. 0.67 3 ? 5.5 0.0 2.1 1.7e+02 9 38 .] 171 200 .. 163 200 .. 0.71 4 ? 4.0 0.0 6.2 5e+02 19 36 .. 233 249 .. 211 251 .. 0.77 5 ? 10.2 0.1 0.068 5.5 11 38 .] 282 308 .. 273 308 .. 0.89 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.96 SSSS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss......vtslafspdgawlasGsdDgtvriW 37 Hs ++ + f++ g +la+G++ g v i+ sp|Q00005|2ABB_HUMAN 17 DHSYateadiISTVEFNHTGELLATGDKGGRVVIF 51 5622345566799*************988888875 PP == domain 2 score: 7.0 bits; conditional E-value: 0.71 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 l+s D+tv++W+ sp|Q00005|2ABB_HUMAN 103 AayfLLSTN-DKTVKLWK 119 344567666.*******6 PP == domain 3 score: 5.5 bits; conditional E-value: 2.1 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++s+++++d +s++ D + +W+ sp|Q00005|2ABB_HUMAN 171 AHtYHINSISVNSDYETYMSAD-DLRINLWN 200 67445****9555555545777.*******8 PP == domain 4 score: 4.0 bits; conditional E-value: 6.2 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 ++ ++++ s+s +gt+r+ sp|Q00005|2ABB_HUMAN 233 HHCNTFVYSSS-KGTIRL 249 44556699999.*****8 PP == domain 5 score: 10.2 bits; conditional E-value: 0.068 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d tv++Wd sp|Q00005|2ABB_HUMAN 282 SSISDVKFSHSGRYIMT-RDYLTVKVWD 308 46999***********6.99*******9 PP >> sp|O75530-3|EED_HUMAN Isoform 3 of Polycomb protein EED OS=Homo sapiens GN=EED # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.0 6.3e-07 5.1e-05 2 38 .] 181 219 .. 180 219 .. 0.89 2 ? 12.5 0.0 0.013 1.1 8 37 .. 233 263 .. 225 264 .. 0.76 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 6.3e-07 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 qc++++ GH + ++ l+f+p + l+ s s+D+ +r+W+ sp|O75530-3|EED_HUMAN 181 QCIKHYVGHgNAINELKFHPRDPNLLlSVSKDHALRLWN 219 8********999*****888888864499*********8 PP == domain 2 score: 12.5 bits; conditional E-value: 0.013 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 +GH + v s +++ g ++s+++D+++++W sp|O75530-3|EED_HUMAN 233 EGHrDEVLSADYDLLGEKIMSCGMDHSLKLW 263 699777999955445555899999******* PP >> sp|Q6RFH5|WDR74_HUMAN WD repeat-containing protein 74 OS=Homo sapiens GN=WDR74 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 7.8 6.3e+02 13 35 .. 45 68 .. 31 71 .. 0.73 2 ? 7.2 0.0 0.6 48 13 38 .] 133 159 .. 122 159 .. 0.77 3 ? 6.2 0.1 1.3 1e+02 13 38 .] 184 211 .. 176 211 .. 0.83 4 ! 13.5 0.0 0.0065 0.53 6 36 .. 264 295 .. 259 297 .. 0.81 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 7.8 EEEEEEETTSSE..EEEEETTSEEE CS WD40 13 vtslafspdgaw..lasGsdDgtvr 35 v++l++ g l+ G+ D+tv+ sp|Q6RFH5|WDR74_HUMAN 45 VSALCWGTGGETqmLV-GCADRTVK 68 7788766666667465.888****9 PP == domain 2 score: 7.2 bits; conditional E-value: 0.6 EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 13 vtslafspdgawl.asGsdDgtvriWd 38 v+ ++ +p ++ + a+G++ + ++iWd sp|Q6RFH5|WDR74_HUMAN 133 VCRMRQDPAHPHVvATGGKENALKIWD 159 6666667777775269**********9 PP == domain 3 score: 6.2 bits; conditional E-value: 1.3 EEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 13 vtsla..fspdgawlasGsdDgtvriWd 38 +++++ f p ++ l++++ + vr++d sp|Q6RFH5|WDR74_HUMAN 184 IWDQDiqFLPGSQKLVTCTGYHQVRVYD 211 555555599999****9966******98 PP == domain 4 score: 13.5 bits; conditional E-value: 0.0065 EEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvri 36 l+G +sv++l+ +p++++las++ D+ +ri sp|Q6RFH5|WDR74_HUMAN 264 CLKGLaGSVRGLQCHPSKPLLASCGLDRVLRI 295 45544445***********************9 PP >> sp|Q8NFP9-3|NBEA_HUMAN Isoform 3 of Neurobeachin OS=Homo sapiens GN=NBEA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.1 1.5 1.2e+02 14 37 .. 474 498 .. 459 499 .. 0.75 2 ? 12.3 0.3 0.015 1.2 4 37 .. 506 544 .. 503 544 .. 0.78 3 ? 4.5 0.0 4.4 3.6e+02 5 29 .. 567 592 .. 564 595 .. 0.77 4 ? 9.7 0.0 0.097 7.9 17 37 .. 662 682 .. 646 683 .. 0.89 5 ? 5.2 0.0 2.5 2.1e+02 2 34 .. 688 721 .. 687 725 .. 0.86 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 1.5 EEEEEETTSSEEE.EEETTSEEEEE CS WD40 14 tslafspdgawla.sGsdDgtvriW 37 +++ + d+++++ +G +D++ r++ sp|Q8NFP9-3|NBEA_HUMAN 474 HCFVVTADNRYILiCGFWDKSFRVY 498 35556779999653888******98 PP == domain 2 score: 12.3 bits; conditional E-value: 0.015 EEEEESSSS.EEEEE....EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtsla....fspdgawlasGsdDgtvriW 37 +++ GH + vt+la + +++sGs+D t+ +W sp|Q8NFP9-3|NBEA_HUMAN 506 TQIVFGHWDvVTCLArsesYIGGDCYIVSGSRDATLLLW 544 555559*3358***9888877777779************ PP == domain 3 score: 4.5 bits; conditional E-value: 4.4 EEEESSSS.EEEEEEETTSSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGs 29 +ltGH++ v +++++ + +++sG sp|Q8NFP9-3|NBEA_HUMAN 567 AVLTGHDHeVVCVSVCAELGLVISGA 592 689***55799**8888888888876 PP == domain 4 score: 9.7 bits; conditional E-value: 0.097 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 s+dg+ l++G+d+g v +W sp|Q8NFP9-3|NBEA_HUMAN 662 LLSSDGQNLVTGGDNGVVEVW 682 5799***************** PP == domain 5 score: 5.2 bits; conditional E-value: 2.5 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtv 34 ++l+++ G ++++++ s+d++ l++G+ g++ sp|Q8NFP9-3|NBEA_HUMAN 688 KQLYIYPGCdAGIRAMDLSHDQRTLITGMASGSI 721 678899999777****************878887 PP >> tr|F5H7J5|F5H7J5_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.16 13 19 38 .] 920 939 .. 900 939 .. 0.71 2 ! 14.8 0.1 0.0025 0.2 4 38 .] 1001 1036 .. 998 1036 .. 0.88 3 ? 5.6 0.0 1.9 1.5e+02 4 38 .] 1046 1082 .. 1043 1082 .. 0.82 4 ? 4.4 0.0 4.7 3.8e+02 11 37 .. 1144 1170 .. 1130 1171 .. 0.80 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.16 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 +d ++l++++dDg +r+W+ tr|F5H7J5|F5H7J5_HUMAN 920 GQDCSLLLTATDDGAIRVWK 939 445567999*9********6 PP == domain 2 score: 14.8 bits; conditional E-value: 0.0025 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 + + tG s+vtsl+ +++ +++++G + Dg++r++d tr|F5H7J5|F5H7J5_HUMAN 1001 QDIPTGAdSCVTSLSCDSHRSLIVAGlG-DGSIRVYD 1036 5567899777****************88.******98 PP == domain 3 score: 5.6 bits; conditional E-value: 1.9 EEEEESS.SS.E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss.v.tslafspdgawlasGsdDgtvriWd 38 + t++ H + v sl+ pdg+ + s s +g vri+d tr|F5H7J5|F5H7J5_HUMAN 1046 VMTYREHtAWvVkASLQKRPDGHIV-SVSVNGDVRIFD 1082 67899997665577999*******8.5677******98 PP == domain 4 score: 4.4 bits; conditional E-value: 4.7 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 + +++laf+p+ + la Gs D + ++ tr|F5H7J5|F5H7J5_HUMAN 1144 GAISCLAFHPHWPHLAVGSNDYYISVY 1170 339****9999999*****9*999887 PP >> sp|Q6RFH5-2|WDR74_HUMAN Isoform 2 of WD repeat-containing protein 74 OS=Homo sapiens GN=WDR74 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7.3 5.9e+02 13 35 .. 45 68 .. 31 71 .. 0.73 2 ? 7.3 0.0 0.56 45 13 38 .] 133 159 .. 122 159 .. 0.77 3 ? 6.3 0.1 1.2 96 13 38 .] 184 211 .. 176 211 .. 0.83 4 ! 13.5 0.0 0.0061 0.49 6 36 .. 264 295 .. 259 297 .. 0.81 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.3 EEEEEEETTSSE..EEEEETTSEEE CS WD40 13 vtslafspdgaw..lasGsdDgtvr 35 v++l++ g l+ G+ D+tv+ sp|Q6RFH5-2|WDR74_HUMAN 45 VSALCWGTGGETqmLV-GCADRTVK 68 7788766666667465.888****9 PP == domain 2 score: 7.3 bits; conditional E-value: 0.56 EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 13 vtslafspdgawl.asGsdDgtvriWd 38 v+ ++ +p ++ + a+G++ + ++iWd sp|Q6RFH5-2|WDR74_HUMAN 133 VCRMRQDPAHPHVvATGGKENALKIWD 159 6666667777775269**********9 PP == domain 3 score: 6.3 bits; conditional E-value: 1.2 EEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 13 vtsla..fspdgawlasGsdDgtvriWd 38 +++++ f p ++ l++++ + vr++d sp|Q6RFH5-2|WDR74_HUMAN 184 IWDQDiqFLPGSQKLVTCTGYHQVRVYD 211 555555599999****9966******98 PP == domain 4 score: 13.5 bits; conditional E-value: 0.0061 EEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvri 36 l+G +sv++l+ +p++++las++ D+ +ri sp|Q6RFH5-2|WDR74_HUMAN 264 CLKGLaGSVRGLQCHPSKPLLASCGLDRVLRI 295 45544445***********************9 PP >> tr|Q6ZW40|Q6ZW40_HUMAN POC1 centriolar protein homolog B OS=Homo sapiens GN=POC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.0 0.2 5.3e-11 4.3e-09 5 38 .] 8 42 .. 4 42 .. 0.85 Alignments for each domain: == domain 1 score: 39.0 bits; conditional E-value: 5.3e-11 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l H +v++ +fspdg++++s+s+D+t++iWd tr|Q6ZW40|Q6ZW40_HUMAN 8 YSLYRHtHWVRCAKFSPDGRLIVSCSEDKTIKIWD 42 555556336*************************9 PP >> tr|F8W921|F8W921_HUMAN Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sapiens GN=SCAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.1 0.026 2.1 6 38 .] 516 547 .. 514 547 .. 0.95 2 ? 9.8 0.0 0.093 7.5 5 37 .. 816 848 .. 812 849 .. 0.72 3 ! 19.0 0.2 0.00011 0.009 2 38 .] 854 890 .. 853 890 .. 0.79 4 ? 6.7 2.0 0.9 73 5 38 .] 899 930 .. 894 930 .. 0.69 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.026 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH ++ +l +dg +l+s++ g+v +Wd tr|F8W921|F8W921_HUMAN 516 VLRGHlMDIECL--ASDGMLLVSCCLAGHVCVWD 547 689**999****..99*****************9 PP == domain 2 score: 9.8 bits; conditional E-value: 0.093 EEEE.SS.SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 5 rtlt.GH.ssvtslafspdgaw....lasGsdDgtvriW 37 +t +H +++t+l + l++Gs D+t+r++ tr|F8W921|F8W921_HUMAN 816 HTVPcAHqKPITAL------KAaagrLVTGSQDHTLRVF 848 4543489999**99......333444679********97 PP == domain 3 score: 19.0 bits; conditional E-value: 0.00011 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 cl tl GH + +t + d+++ lasG+ Dg + +Wd tr|F8W921|F8W921_HUMAN 854 CCLFTLQGHsGAITTV--YIDQTMvLASGGQDGAICLWD 890 599******5559999..3344444689**********9 PP == domain 4 score: 6.7 bits; conditional E-value: 0.9 EEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +++ +H ++vtsl + ++s++ D + iWd tr|F8W921|F8W921_HUMAN 899 HVF-AHrGDVTSL------TCttscVISSGLDDLISIWD 930 445.899999999......333343556666*******9 PP >> tr|H0YLA1|H0YLA1_HUMAN WD repeat-containing protein 61 (Fragment) OS=Homo sapiens GN=WDR61 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 0.0 4.4e-11 3.5e-09 4 38 .] 2 37 .. 1 37 [. 0.96 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 4.4e-11 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+tl+GH +++sl fspd+++l+++sdDg ++i+d tr|H0YLA1|H0YLA1_HUMAN 2 LHTLEGHaMPIRSLTFSPDSQLLVTASDDGYIKIYD 37 8******888*************************8 PP >> sp|Q00005-4|2ABB_HUMAN Isoform 4 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 1.1 91 9 37 .. 75 109 .. 69 110 .. 0.76 2 ? 6.8 0.0 0.83 67 24 38 .] 161 177 .. 128 177 .. 0.67 3 ? 5.3 0.0 2.4 2e+02 9 38 .] 229 258 .. 221 258 .. 0.71 4 ? 3.8 0.0 7.2 5.9e+02 19 36 .. 291 307 .. 269 309 .. 0.77 5 ? 10.0 0.1 0.08 6.5 11 38 .] 340 366 .. 331 366 .. 0.89 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 1.1 SSSS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss......vtslafspdgawlasGsdDgtvriW 37 Hs ++ + f++ g +la+G++ g v i+ sp|Q00005-4|2ABB_HUMAN 75 DHSYateadiISTVEFNHTGELLATGDKGGRVVIF 109 5522345566799*************988888875 PP == domain 2 score: 6.8 bits; conditional E-value: 0.83 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 l+s D+tv++W+ sp|Q00005-4|2ABB_HUMAN 161 AayfLLSTN-DKTVKLWK 177 344567666.*******6 PP == domain 3 score: 5.3 bits; conditional E-value: 2.4 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++s+++++d +s++ D + +W+ sp|Q00005-4|2ABB_HUMAN 229 AHtYHINSISVNSDYETYMSAD-DLRINLWN 258 67445****9555555545777.*******8 PP == domain 4 score: 3.8 bits; conditional E-value: 7.2 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 ++ ++++ s+s +gt+r+ sp|Q00005-4|2ABB_HUMAN 291 HHCNTFVYSSS-KGTIRL 307 44556699999.*****8 PP == domain 5 score: 10.0 bits; conditional E-value: 0.08 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d tv++Wd sp|Q00005-4|2ABB_HUMAN 340 SSISDVKFSHSGRYIMT-RDYLTVKVWD 366 46999***********6.99*******9 PP >> tr|C9JBE7|C9JBE7_HUMAN WD repeat-containing protein 53 OS=Homo sapiens GN=WDR53 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.0 0.079 6.4 14 37 .. 42 65 .. 31 66 .. 0.79 2 ! 26.7 0.0 4.3e-07 3.4e-05 7 38 .] 78 110 .. 71 110 .. 0.90 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.079 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 +s+++ + g+ +++G +Dg+vri+ tr|C9JBE7|C9JBE7_HUMAN 42 HSISVASCGNIFSCGAEDGKVRIF 65 3555677799999999*******7 PP == domain 2 score: 26.7 bits; conditional E-value: 4.3e-07 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++GH s+v+ ++f p++ +l++G+ Dg++ +Wd tr|C9JBE7|C9JBE7_HUMAN 78 FKGHtSGVSQVCFLPESYLLLTGGNDGKITLWD 110 79**888*************************9 PP >> tr|C9JJZ8|C9JJZ8_HUMAN WD repeat-containing protein 53 OS=Homo sapiens GN=WDR53 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.0 0.078 6.3 14 37 .. 40 63 .. 29 64 .. 0.79 2 ! 26.7 0.0 4.2e-07 3.4e-05 7 38 .] 76 108 .. 69 108 .. 0.90 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.078 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 +s+++ + g+ +++G +Dg+vri+ tr|C9JJZ8|C9JJZ8_HUMAN 40 HSISVASCGNIFSCGAEDGKVRIF 63 3555677799999999*******7 PP == domain 2 score: 26.7 bits; conditional E-value: 4.2e-07 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++GH s+v+ ++f p++ +l++G+ Dg++ +Wd tr|C9JJZ8|C9JJZ8_HUMAN 76 FKGHtSGVSQVCFLPESYLLLTGGNDGKITLWD 108 79**888*************************9 PP >> sp|Q9BQA1|MEP50_HUMAN Methylosome protein 50 OS=Homo sapiens GN=WDR77 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.7 0.062 5 9 38 .] 123 153 .. 116 153 .. 0.87 2 ! 25.5 0.1 9.9e-07 8e-05 4 38 .] 160 196 .. 157 196 .. 0.83 3 ? 3.6 0.3 8.2 6.6e+02 8 33 .. 252 279 .. 245 282 .. 0.69 4 ? 4.6 0.1 4.1 3.3e+02 8 34 .. 294 322 .. 286 323 .. 0.82 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.062 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 H++ v+ +++ ++g+ +sGs+D +++Wd sp|Q9BQA1|MEP50_HUMAN 123 EHDDiVSTVSVLSSGTQAVSGSKDICIKVWD 153 48555799*********9************9 PP == domain 2 score: 25.5 bits; conditional E-value: 9.9e-07 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 l ++++H vt++a sp+++ ++ s+s+D+ + +Wd sp|Q9BQA1|MEP50_HUMAN 160 LSSYRAHaAQVTCVAASPHKDSVFlSCSEDNRILLWD 196 789****777*****77777775339**********9 PP == domain 3 score: 3.6 bits; conditional E-value: 8.2 ESS.SSEEEEEEETTSSEEEEE.ETTSE CS WD40 8 tGH.ssvtslafspdgawlasG.sdDgt 33 H ++vt+l fsp++ ++++ s+D++ sp|Q9BQA1|MEP50_HUMAN 252 AVHsQCVTGLVFSPHSVPFLASlSEDCS 279 4686669***999998766655566666 PP == domain 4 score: 4.6 bits; conditional E-value: 4.1 ESS.SSEEEEEEETTSSEEEEE.ETTSEE CS WD40 8 tGH.ssvtslafspdgawlasG.sdDgtv 34 +H ++v++ +sp ++ l++ ++D+ v sp|Q9BQA1|MEP50_HUMAN 294 QAHrDFVRDATWSPLNHSLLTTvGWDHQV 322 489888****99999999986669**987 PP >> sp|Q00005-5|2ABB_HUMAN Isoform 5 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 1.1 93 9 37 .. 83 117 .. 77 118 .. 0.76 2 ? 6.8 0.0 0.84 68 24 38 .] 169 185 .. 136 185 .. 0.67 3 ? 5.3 0.0 2.5 2e+02 9 38 .] 237 266 .. 229 266 .. 0.71 4 ? 3.8 0.0 7.4 6e+02 19 36 .. 299 315 .. 277 317 .. 0.77 5 ? 10.0 0.1 0.081 6.6 11 38 .] 348 374 .. 339 374 .. 0.89 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 1.1 SSSS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss......vtslafspdgawlasGsdDgtvriW 37 Hs ++ + f++ g +la+G++ g v i+ sp|Q00005-5|2ABB_HUMAN 83 DHSYateadiISTVEFNHTGELLATGDKGGRVVIF 117 5522345566799*************988888875 PP == domain 2 score: 6.8 bits; conditional E-value: 0.84 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 l+s D+tv++W+ sp|Q00005-5|2ABB_HUMAN 169 AayfLLSTN-DKTVKLWK 185 344567666.*******6 PP == domain 3 score: 5.3 bits; conditional E-value: 2.5 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++s+++++d +s++ D + +W+ sp|Q00005-5|2ABB_HUMAN 237 AHtYHINSISVNSDYETYMSAD-DLRINLWN 266 67445****9555555545777.*******8 PP == domain 4 score: 3.8 bits; conditional E-value: 7.4 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 ++ ++++ s+s +gt+r+ sp|Q00005-5|2ABB_HUMAN 299 HHCNTFVYSSS-KGTIRL 315 44556699999.*****8 PP == domain 5 score: 10.0 bits; conditional E-value: 0.081 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d tv++Wd sp|Q00005-5|2ABB_HUMAN 348 SSISDVKFSHSGRYIMT-RDYLTVKVWD 374 46999***********6.99*******9 PP >> sp|Q9HBG6-4|IF122_HUMAN Isoform 4 of Intraflagellar transport protein 122 homolog OS=Homo sapiens GN=IFT122 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.74 60 10 34 .. 13 45 .. 4 47 .. 0.77 2 ? 12.6 0.3 0.012 0.99 2 31 .. 44 91 .. 43 108 .. 0.76 3 ? 10.9 0.1 0.043 3.5 7 37 .. 206 237 .. 200 238 .. 0.79 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.74 SSSEEEEEEETTSSE..EEEEET.......TSEE CS WD40 10 Hssvtslafspdgaw..lasGsd.......Dgtv 34 H +++++af pdg+ la+Gs+ Dgt+ sp|Q9HBG6-4|IF122_HUMAN 13 H-CINDIAFKPDGTQliLAAGSRllvydtsDGTL 45 6.7************4446898666666667776 PP == domain 2 score: 12.6 bits; conditional E-value: 0.012 EEEEEEESSSS.EEEEEEETTSSE...............EEEEET..T CS WD40 2 qclrtltGHss.vtslafspdgaw...............lasGsd..D 31 ++l+ l+GH++ v+++a+ +dg w ++++s+ D sp|Q9HBG6-4|IF122_HUMAN 44 TLLQPLKGHKDtVYCVAYAKDGLWspeqksvskhkssskIICCSWtnD 91 678999***555*****8888888777777777777777666765445 PP == domain 3 score: 10.9 bits; conditional E-value: 0.043 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ sp|Q9HBG6-4|IF122_HUMAN 206 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 237 444545698888*****************876 PP >> sp|P63151|2ABA_HUMAN Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapie # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.92 74 12 37 .. 24 55 .. 11 56 .. 0.73 2 ? 7.2 0.0 0.63 51 23 38 .] 109 123 .. 74 123 .. 0.73 3 ? 4.6 0.1 4.1 3.3e+02 9 37 .. 175 203 .. 167 204 .. 0.73 4 ? 4.8 0.0 3.5 2.8e+02 14 36 .. 230 253 .. 219 255 .. 0.76 5 ? 8.9 0.1 0.18 15 11 38 .] 286 312 .. 277 312 .. 0.89 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.92 S......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s......vtslafspdgawlasGsdDgtvriW 37 + ++ + f+++g +la+G++ g v i+ sp|P63151|2ABA_HUMAN 24 DvaeadiISTVEFNHSGELLATGDKGGRVVIF 55 144455568999***********988888875 PP == domain 2 score: 7.2 bits; conditional E-value: 0.63 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++l+s D+t+++W+ sp|P63151|2ABA_HUMAN 109 QFLLSTN-DKTIKLWK 123 4488766.*******6 PP == domain 3 score: 4.6 bits; conditional E-value: 4.1 SS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla.fspdgawlasGsdDgtvriW 37 +H +++s++ +s++ ++l s++ D + +W sp|P63151|2ABA_HUMAN 175 AHtYHINSISiNSDYETYL-SAD-DLRINLW 203 67445****9677777776.677.*999999 PP == domain 4 score: 4.8 bits; conditional E-value: 3.5 EEEEEETTSSE..EEEEETTSEEEE CS WD40 14 tslafspdgaw..lasGsdDgtvri 36 t+ f+p++ + s+s +gt+r+ sp|P63151|2ABA_HUMAN 230 TAAEFHPNSCNtfVYSSS-KGTIRL 253 566666666666588999.*****8 PP == domain 5 score: 8.9 bits; conditional E-value: 0.18 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d +v+iWd sp|P63151|2ABA_HUMAN 286 SSISDVKFSHSGRYMMT-RDYLSVKIWD 312 46999***********6.89*******9 PP >> tr|J3KSI1|J3KSI1_HUMAN Cirhin (Fragment) OS=Homo sapiens GN=CIRH1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 0.0016 0.13 12 37 .. 55 80 .. 47 81 .. 0.89 2 ? 11.8 0.0 0.022 1.8 11 31 .. 98 118 .. 88 121 .. 0.81 3 ? 5.0 0.3 3.1 2.5e+02 13 38 .] 150 174 .. 140 174 .. 0.82 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0016 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +++s+a sp+g+ l+ G++Dg+v+++ tr|J3KSI1|J3KSI1_HUMAN 55 PIWSMAASPSGSQLLVGCEDGSVKLF 80 59**********************97 PP == domain 2 score: 11.8 bits; conditional E-value: 0.022 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 s + sl+++p+g+ +a+Gs D tr|J3KSI1|J3KSI1_HUMAN 98 SRILSLSWHPSGTHIAAGSID 118 4499**************966 PP == domain 3 score: 5.0 bits; conditional E-value: 3.1 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v+++af +dg+ ++ s g+v +Wd tr|J3KSI1|J3KSI1_HUMAN 150 VWGVAFLSDGTIISVDS-AGKVQFWD 174 79**********86446.99999998 PP >> tr|U3KQQ3|U3KQQ3_HUMAN WD repeat-containing protein 18 (Fragment) OS=Homo sapiens GN=WDR18 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 0.0 0.15 12 12 37 .. 72 96 .. 62 97 .. 0.81 2 ! 22.5 0.6 8.7e-06 0.0007 2 38 .] 102 139 .. 101 139 .. 0.93 3 ? 6.4 0.2 1.1 87 4 35 .. 155 189 .] 153 189 .] 0.82 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.15 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +vt+l sp+g ++++G ++++W tr|U3KQQ3|U3KQQ3_HUMAN 72 PVTCLTASPNGLYVLAGV-AESIHLW 96 5**************886.7777777 PP == domain 2 score: 22.5 bits; conditional E-value: 8.7e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l +l+ H ++v++l+f d++ ++sG++D+ v +W+ tr|U3KQQ3|U3KQQ3_HUMAN 102 NLLVILSRHyQDVSCLQFTGDSSHFISGGKDCLVLVWS 139 67888999*99**************************5 PP == domain 3 score: 6.4 bits; conditional E-value: 1.1 EEEEESS.SSEEEEEEETTSSE..EEEEETTSEEE CS WD40 4 lrtltGH.ssvtslafspdgaw..lasGsdDgtvr 35 ++++ H ++t+l g++ +a++s D+tv+ tr|U3KQQ3|U3KQQ3_HUMAN 155 RHVWSHHaLPITDLHCGFGGPLarVATSSLDQTVK 189 5778888777****9888888877899999***98 PP >> sp|Q00005-3|2ABB_HUMAN Isoform 3 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.0 2 1.7e+02 12 37 .. 31 57 .. 14 58 .. 0.80 2 ? 7.0 0.0 0.72 58 24 38 .] 109 125 .. 76 125 .. 0.67 3 ? 5.5 0.0 2.1 1.7e+02 9 38 .] 177 206 .. 169 206 .. 0.71 4 ? 4.0 0.0 6.3 5.1e+02 19 36 .. 239 255 .. 217 257 .. 0.77 5 ? 10.2 0.1 0.07 5.6 11 38 .] 288 314 .. 279 314 .. 0.89 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 2 S.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriW 37 + ++ + f++ g +la+G++ g v i+ sp|Q00005-3|2ABB_HUMAN 31 DiISTVEFNHTGELLATGDKGGRVVIF 57 3479999***********988888875 PP == domain 2 score: 7.0 bits; conditional E-value: 0.72 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 l+s D+tv++W+ sp|Q00005-3|2ABB_HUMAN 109 AayfLLSTN-DKTVKLWK 125 344567666.*******6 PP == domain 3 score: 5.5 bits; conditional E-value: 2.1 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++s+++++d +s++ D + +W+ sp|Q00005-3|2ABB_HUMAN 177 AHtYHINSISVNSDYETYMSAD-DLRINLWN 206 67445****9555555545777.*******8 PP == domain 4 score: 4.0 bits; conditional E-value: 6.3 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 ++ ++++ s+s +gt+r+ sp|Q00005-3|2ABB_HUMAN 239 HHCNTFVYSSS-KGTIRL 255 44556699999.*****8 PP == domain 5 score: 10.2 bits; conditional E-value: 0.07 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d tv++Wd sp|Q00005-3|2ABB_HUMAN 288 SSISDVKFSHSGRYIMT-RDYLTVKVWD 314 46999***********6.99*******9 PP >> sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.0 0.18 15 19 38 .] 1078 1097 .. 1058 1097 .. 0.71 2 ! 14.6 0.1 0.0029 0.23 4 38 .] 1159 1194 .. 1156 1194 .. 0.88 3 ? 5.5 0.0 2.2 1.8e+02 4 38 .] 1204 1240 .. 1201 1240 .. 0.82 4 ? 4.2 0.0 5.4 4.4e+02 11 37 .. 1302 1328 .. 1288 1329 .. 0.80 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.18 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 +d ++l++++dDg +r+W+ sp|Q8N122|RPTOR_HUMAN 1078 GQDCSLLLTATDDGAIRVWK 1097 445567999*9********6 PP == domain 2 score: 14.6 bits; conditional E-value: 0.0029 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 + + tG s+vtsl+ +++ +++++G + Dg++r++d sp|Q8N122|RPTOR_HUMAN 1159 QDIPTGAdSCVTSLSCDSHRSLIVAGlG-DGSIRVYD 1194 5567899777****************88.******98 PP == domain 3 score: 5.5 bits; conditional E-value: 2.2 EEEEESS.SS.E.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss.v.tslafspdgawlasGsdDgtvriWd 38 + t++ H + v sl+ pdg+ + s s +g vri+d sp|Q8N122|RPTOR_HUMAN 1204 VMTYREHtAWvVkASLQKRPDGHIV-SVSVNGDVRIFD 1240 67899997665577999*******8.5677******98 PP == domain 4 score: 4.2 bits; conditional E-value: 5.4 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 + +++laf+p+ + la Gs D + ++ sp|Q8N122|RPTOR_HUMAN 1302 GAISCLAFHPHWPHLAVGSNDYYISVY 1328 339****9999999*****9*999887 PP >> tr|E9PPG9|E9PPG9_HUMAN mRNA export factor OS=Homo sapiens GN=RAE1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.6 5.2 4.2e+02 22 37 .. 54 69 .. 22 70 .. 0.72 2 ! 21.9 0.2 1.4e-05 0.0011 10 38 .] 85 114 .. 78 114 .. 0.91 3 ! 16.8 0.2 0.00058 0.047 19 38 .] 138 157 .. 119 157 .. 0.71 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 5.2 SSEEEEEETTSEEEEE CS WD40 22 gawlasGsdDgtvriW 37 g++l++Gs+ + vr W tr|E9PPG9|E9PPG9_HUMAN 54 GNFLIAGSWANDVRCW 69 566999***9999999 PP == domain 2 score: 21.9 bits; conditional E-value: 1.4e-05 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H ++v ++++s+dg+ ++++s D+t ++Wd tr|E9PPG9|E9PPG9_HUMAN 85 HtGPVLDVCWSDDGSKVFTASCDKTAKMWD 114 7667*************99988*******9 PP == domain 3 score: 16.8 bits; conditional E-value: 0.00058 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 p+ + +++Gs+D+t+++Wd tr|E9PPG9|E9PPG9_HUMAN 138 APNYSCVMTGSWDKTLKFWD 157 35555599***********9 PP >> sp|Q00005-7|2ABB_HUMAN Isoform 7 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 1.3 1e+02 9 37 .. 123 157 .. 117 158 .. 0.76 2 ? 6.6 0.0 0.93 75 24 38 .] 209 225 .. 176 225 .. 0.68 3 ? 5.2 0.0 2.7 2.2e+02 9 38 .] 277 306 .. 269 306 .. 0.71 4 ? 3.7 0.0 8.1 6.6e+02 19 36 .. 339 355 .. 317 357 .. 0.77 5 ? 9.8 0.1 0.089 7.2 11 38 .] 388 414 .. 379 414 .. 0.89 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 1.3 SSSS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss......vtslafspdgawlasGsdDgtvriW 37 Hs ++ + f++ g +la+G++ g v i+ sp|Q00005-7|2ABB_HUMAN 123 DHSYateadiISTVEFNHTGELLATGDKGGRVVIF 157 5522345566799*************988888875 PP == domain 2 score: 6.6 bits; conditional E-value: 0.93 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 l+s D+tv++W+ sp|Q00005-7|2ABB_HUMAN 209 AayfLLSTN-DKTVKLWK 225 344567666.*******6 PP == domain 3 score: 5.2 bits; conditional E-value: 2.7 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++s+++++d +s++ D + +W+ sp|Q00005-7|2ABB_HUMAN 277 AHtYHINSISVNSDYETYMSAD-DLRINLWN 306 67445****9555555545777.*******8 PP == domain 4 score: 3.7 bits; conditional E-value: 8.1 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 ++ ++++ s+s +gt+r+ sp|Q00005-7|2ABB_HUMAN 339 HHCNTFVYSSS-KGTIRL 355 44556699999.*****8 PP == domain 5 score: 9.8 bits; conditional E-value: 0.089 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d tv++Wd sp|Q00005-7|2ABB_HUMAN 388 SSISDVKFSHSGRYIMT-RDYLTVKVWD 414 46999***********6.99*******9 PP >> sp|Q8WUA4|TF3C2_HUMAN General transcription factor 3C polypeptide 2 OS=Homo sapiens GN=GTF3C2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.052 4.2 12 37 .. 468 511 .. 451 512 .. 0.83 2 ! 15.6 0.1 0.0014 0.11 6 38 .] 608 642 .. 600 642 .. 0.72 3 ? 4.2 0.0 5.5 4.5e+02 8 36 .. 822 863 .. 817 864 .. 0.66 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.052 S.EEEEEEETTSSE...................EEEEETTSEEEEE CS WD40 12 s.vtslafspdgaw...................lasGsdDgtvriW 37 + +++l+f+p+gaw l ++s Dg+v ++ sp|Q8WUA4|TF3C2_HUMAN 468 GcIWDLKFCPSGAWelpgtprkapllprlgllaL-ACS-DGKVLLF 511 2499999***********************8533.79*.***9886 PP == domain 2 score: 15.6 bits; conditional E-value: 0.0014 EEESS.SSEEEEEEETTSSE.EE.EEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw.la.sGsdDgtvriWd 38 + +H + v+ l++++ ++ l+ +Gs D+++++Wd sp|Q8WUA4|TF3C2_HUMAN 608 CFLAHdQAVRTLQWCKANSHfLVsAGS-DRKIKFWD 642 566897779999755555555552567.*******9 PP == domain 3 score: 4.2 bits; conditional E-value: 5.5 ESSSS..........EEEEEEETTSSE...EEEEETTSEEEE CS WD40 8 tGHss..........vtslafspdgaw...lasGsdDgtvri 36 +GHs ++ ++fsp+ + l+sG+ g vri sp|Q8WUA4|TF3C2_HUMAN 822 EGHSQlcldrlqleaIHKVRFSPNLDSygwLVSGGQSGLVRI 863 5774434444444445555667766666669****9999998 PP >> sp|Q64LD2-2|WDR25_HUMAN Isoform 2 of WD repeat-containing protein 25 OS=Homo sapiens GN=WDR25 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.1 0.044 3.6 1 35 [. 25 60 .. 25 63 .. 0.87 2 ! 15.7 0.0 0.0012 0.1 5 37 .. 208 243 .. 205 244 .. 0.79 3 ? 6.9 0.3 0.77 63 6 37 .. 253 286 .. 250 287 .] 0.67 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.044 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvr 35 g cl+t++ H v++ ++ p g+ ++sG+ D ++ sp|Q64LD2-2|WDR25_HUMAN 25 GHCLQTYSLHtEAVRAARWAPCGRRILSGGFDFALH 60 579*******777****************9887665 PP == domain 2 score: 15.7 bits; conditional E-value: 0.0012 EEEESS..SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH..ss..vtslafspdgawlasGsdDgtvriW 37 r ++GH + v ++ sp g++l++Gs Dg v ++ sp|Q64LD2-2|WDR25_HUMAN 208 RRYEGHkvEGysV-GCECSPGGDLLVTGSADGRVLMY 243 5689995422567.6668***************9886 PP == domain 3 score: 6.9 bits; conditional E-value: 0.77 EEESS.SS.E.E.......EEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ss.v.t.......slafspdgawlasGsdDgtvriW 37 tl GH + v t s+ la++s+ g +iW sp|Q64LD2-2|WDR25_HUMAN 253 TLQGHtQAcVgTtyhpvlpSV--------LATCSWGGDMKIW 286 567885334432333333466........99*********** PP >> tr|H3BLT2|H3BLT2_HUMAN WD repeat- and FYVE domain-containing protein 4 (Fragment) OS=Homo sapiens GN=WDFY4 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.1 2.4e-05 0.0019 7 38 .] 1065 1097 .. 1059 1097 .. 0.90 2 ! 16.5 0.1 0.00072 0.058 2 38 .] 1142 1187 .. 1141 1187 .. 0.73 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 2.4e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH + vt+la s ++l+sGs D+t+ +Wd tr|H3BLT2|H3BLT2_HUMAN 1065 LYGHtQAVTCLAASVTFSLLVSGSQDCTCILWD 1097 77**888*****99999***************9 PP == domain 2 score: 16.5 bits; conditional E-value: 0.00072 EEEEEEESS.SS...EEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ss...vtsla......fspdgawlasGsdDgtvriWd 38 q+l ++t+ ++ +t+++ ++ ++ + +Gs Dg vr+W+ tr|H3BLT2|H3BLT2_HUMAN 1142 QPLASITTAwGPegaITCCClmegpaWDTSQIII-TGSQDGMVRVWK 1187 667777655434556*****77777777777765.8**********6 PP >> tr|G3V1J0|G3V1J0_HUMAN WD repeat domain 55, isoform CRA_b OS=Homo sapiens GN=WDR55 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 1.8 1.5e+02 9 38 .] 5 35 .. 2 35 .. 0.81 2 ? 4.3 0.0 5.1 4.1e+02 21 38 .] 60 77 .. 44 79 .. 0.71 3 ? 4.2 0.0 5.6 4.5e+02 15 35 .. 104 116 .. 92 117 .. 0.81 4 ! 19.6 0.0 7.6e-05 0.0062 5 38 .] 127 162 .. 123 162 .. 0.82 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 1.8 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H + ++a +p +++l+++s Dg + i++ tr|G3V1J0|G3V1J0_HUMAN 5 QHeEYIADMALDPAKKLLLTASGDGCLGIFN 35 57555999999*******99877**987765 PP == domain 2 score: 4.3 bits; conditional E-value: 5.1 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 g+ +a+Gs gt+++++ tr|G3V1J0|G3V1J0_HUMAN 60 WGKKVACGSSEGTIYLFN 77 3444999*88*****976 PP == domain 3 score: 4.2 bits; conditional E-value: 5.6 EEEEETTSSEEEEEETTSEEE CS WD40 15 slafspdgawlasGsdDgtvr 35 sl l++Gs Dg +r tr|G3V1J0|G3V1J0_HUMAN 104 SL--------LCTGSTDGVIR 116 45........99*******98 PP == domain 4 score: 19.6 bits; conditional E-value: 7.6e-05 EEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 ++ H +v la s+ g++las++ D+ +++Wd tr|G3V1J0|G3V1J0_HUMAN 127 GSVGQHtgEPVEELALSHCGRFLASSGHDQRLKFWD 162 5666785444**************8777*******9 PP >> tr|H0Y711|H0Y711_HUMAN Methylosome protein 50 (Fragment) OS=Homo sapiens GN=WDR77 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.7 0.05 4 9 38 .] 60 90 .. 53 90 .. 0.87 2 ! 25.8 0.1 7.9e-07 6.4e-05 4 38 .] 97 133 .. 94 133 .. 0.83 3 ? 4.9 0.1 3.3 2.7e+02 8 34 .. 243 271 .. 235 272 .. 0.82 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.05 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 H++ v+ +++ ++g+ +sGs+D +++Wd tr|H0Y711|H0Y711_HUMAN 60 EHDDiVSTVSVLSSGTQAVSGSKDICIKVWD 90 4855579**********9************9 PP == domain 2 score: 25.8 bits; conditional E-value: 7.9e-07 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 l ++++H vt++a sp+++ ++ s+s+D+ + +Wd tr|H0Y711|H0Y711_HUMAN 97 LSSYRAHaAQVTCVAASPHKDSVFlSCSEDNRILLWD 133 789****777*****77777775339**********9 PP == domain 3 score: 4.9 bits; conditional E-value: 3.3 ESS.SSEEEEEEETTSSEEEEE.ETTSEE CS WD40 8 tGH.ssvtslafspdgawlasG.sdDgtv 34 +H ++v++ +sp ++ l++ ++D+ v tr|H0Y711|H0Y711_HUMAN 243 QAHrDFVRDATWSPLNHSLLTTvGWDHQV 271 489888****99999999986669**987 PP >> tr|E9PS41|E9PS41_HUMAN WD repeat-containing protein 74 OS=Homo sapiens GN=WDR74 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 9.8 7.9e+02 20 37 .. 39 55 .. 21 56 .. 0.86 2 ? 7.5 0.0 0.48 39 13 38 .] 76 102 .. 65 102 .. 0.77 3 ? 6.5 0.1 1 83 13 38 .] 127 154 .. 119 154 .. 0.83 4 ! 13.8 0.0 0.0052 0.42 6 36 .. 207 238 .. 202 240 .. 0.81 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 9.8 TTSSEEEEEETTSEEEEE CS WD40 20 pdgawlasGsdDgtvriW 37 dg+++ ++ d g +r+W tr|E9PS41|E9PS41_HUMAN 39 ADGTLI-TCVDSGILRVW 55 577886.6888******* PP == domain 2 score: 7.5 bits; conditional E-value: 0.48 EEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 13 vtslafspdgawl.asGsdDgtvriWd 38 v+ ++ +p ++ + a+G++ + ++iWd tr|E9PS41|E9PS41_HUMAN 76 VCRMRQDPAHPHVvATGGKENALKIWD 102 6666667777775269**********9 PP == domain 3 score: 6.5 bits; conditional E-value: 1 EEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 13 vtsla..fspdgawlasGsdDgtvriWd 38 +++++ f p ++ l++++ + vr++d tr|E9PS41|E9PS41_HUMAN 127 IWDQDiqFLPGSQKLVTCTGYHQVRVYD 154 55555559999*****9966******98 PP == domain 4 score: 13.8 bits; conditional E-value: 0.0052 EEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvri 36 l+G +sv++l+ +p++++las++ D+ +ri tr|E9PS41|E9PS41_HUMAN 207 CLKGLaGSVRGLQCHPSKPLLASCGLDRVLRI 238 45544445***********************9 PP >> sp|P63151-2|2ABA_HUMAN Isoform 2 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isofor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.1 0.88 71 12 37 .. 34 65 .. 12 66 .. 0.75 2 ? 7.1 0.0 0.65 52 23 38 .] 119 133 .. 84 133 .. 0.73 3 ? 4.5 0.1 4.2 3.4e+02 9 37 .. 185 213 .. 177 214 .. 0.73 4 ? 4.8 0.0 3.6 2.9e+02 14 36 .. 240 263 .. 229 265 .. 0.76 5 ? 8.8 0.1 0.18 15 11 38 .] 296 322 .. 287 322 .. 0.89 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.88 S......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s......vtslafspdgawlasGsdDgtvriW 37 + ++ + f+++g +la+G++ g v i+ sp|P63151-2|2ABA_HUMAN 34 DvaeadiISTVEFNHSGELLATGDKGGRVVIF 65 144445468889***********988888875 PP == domain 2 score: 7.1 bits; conditional E-value: 0.65 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++l+s D+t+++W+ sp|P63151-2|2ABA_HUMAN 119 QFLLSTN-DKTIKLWK 133 4488766.*******6 PP == domain 3 score: 4.5 bits; conditional E-value: 4.2 SS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla.fspdgawlasGsdDgtvriW 37 +H +++s++ +s++ ++l s++ D + +W sp|P63151-2|2ABA_HUMAN 185 AHtYHINSISiNSDYETYL-SAD-DLRINLW 213 67445****9677777776.677.*999999 PP == domain 4 score: 4.8 bits; conditional E-value: 3.6 EEEEEETTSSE..EEEEETTSEEEE CS WD40 14 tslafspdgaw..lasGsdDgtvri 36 t+ f+p++ + s+s +gt+r+ sp|P63151-2|2ABA_HUMAN 240 TAAEFHPNSCNtfVYSSS-KGTIRL 263 566666666666588999.*****8 PP == domain 5 score: 8.8 bits; conditional E-value: 0.18 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d +v+iWd sp|P63151-2|2ABA_HUMAN 296 SSISDVKFSHSGRYMMT-RDYLSVKIWD 322 46999***********6.89*******9 PP >> tr|B5MC98|B5MC98_HUMAN Prolactin regulatory element-binding protein OS=Homo sapiens GN=PREB PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 6.1e-05 0.005 16 38 .] 160 182 .. 144 182 .. 0.90 2 ? 11.1 0.0 0.036 2.9 3 37 .. 188 222 .. 186 223 .. 0.85 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 6.1e-05 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 ++f++d+++la+G+ Dg vr+W+ tr|B5MC98|B5MC98_HUMAN 160 VCFNHDNTLLATGGTDGYVRVWK 182 679**********99*******6 PP == domain 2 score: 11.1 bits; conditional E-value: 0.036 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++ ++++H + + +la pdg++++ G D + +W tr|B5MC98|B5MC98_HUMAN 188 KVLEFKAHeGEIEDLALGPDGKLVTVGR-DLKASVW 222 56789***888************98776.9888888 PP >> tr|I3L2Y6|I3L2Y6_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.7 0.1 2.5e-09 2.1e-07 4 37 .. 70 105 .. 67 106 .. 0.88 Alignments for each domain: == domain 1 score: 33.7 bits; conditional E-value: 2.5e-09 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriW 37 + +l Hs+ vt+l+fsp ++l a+Gs D+tv++W tr|I3L2Y6|I3L2Y6_HUMAN 70 VAHLGCHSDlVTDLDFSPFDDFLlATGSADRTVKLW 105 679999*8889***********7369********** PP >> tr|C9IZR2|C9IZR2_HUMAN Intraflagellar transport protein 80 homolog (Fragment) OS=Homo sapiens GN=IFT80 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 2.5 2e+02 10 29 .. 9 30 .. 2 36 .. 0.72 2 ! 14.9 0.4 0.0023 0.18 6 38 .] 46 79 .. 41 79 .. 0.86 3 ! 15.6 0.0 0.0014 0.11 10 29 .. 91 111 .. 82 121 .. 0.77 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 2.5 S.SSEEEEEEETTSSEEE.EEE CS WD40 10 H.ssvtslafspdgawla.sGs 29 + ++v+s+a+ pd+ ++ +++ tr|C9IZR2|C9IZR2_HUMAN 9 QgTPVYSVAWGPDSEKVLyTAG 30 3457*********998654655 PP == domain 2 score: 14.9 bits; conditional E-value: 0.0023 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++H++ + +++++ +++++s+++D++ ++Wd tr|C9IZR2|C9IZR2_HUMAN 46 QWKAHDGiILKVDWNSVNDLILSAGEDCKYKVWD 79 4689*55479***********************9 PP == domain 3 score: 15.6 bits; conditional E-value: 0.0014 S.SSEEEEEEETTSSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGs 29 H ++ts+a+ pdg ++a Gs tr|C9IZR2|C9IZR2_HUMAN 91 HeHPITSVAWAPDGELFAVGS 111 5338**************998 PP >> tr|C9K0E4|C9K0E4_HUMAN Syntaxin-binding protein 5-like OS=Homo sapiens GN=STXBP5L PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.56 45 21 38 .] 123 139 .. 102 139 .. 0.67 2 ? 6.7 0.0 0.87 70 8 38 .] 205 237 .. 199 237 .. 0.82 3 ? 12.6 0.1 0.012 0.95 12 38 .] 252 278 .. 242 278 .. 0.86 4 ? 10.7 0.3 0.048 3.9 24 38 .] 460 477 .. 406 477 .. 0.82 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.56 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +ga+++++s D t+++W+ tr|C9K0E4|C9K0E4_HUMAN 123 EGALVSASS-DDTLHLWN 139 455565556.*******8 PP == domain 2 score: 6.7 bits; conditional E-value: 0.87 ESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 ++H ++v +l+ ++g++l+ G ++gtv +Wd tr|C9K0E4|C9K0E4_HUMAN 205 KTHpGPVVHLSdsPRDEGKLLI-GYENGTVVFWD 237 6798889999987777777776.**********9 PP == domain 3 score: 12.6 bits; conditional E-value: 0.012 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++++++g+ +++++ Dg++ +W+ tr|C9K0E4|C9K0E4_HUMAN 252 AIHSIDWHHEGKQFMCSHSDGSLTLWN 278 39*************9988*******8 PP == domain 4 score: 10.7 bits; conditional E-value: 0.048 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 + +++G+ Dg++++Wd tr|C9K0E4|C9K0E4_HUMAN 460 YpeiIITGHADGSIKFWD 477 155488***********9 PP >> tr|C9JYH8|C9JYH8_HUMAN WD repeat domain 45, isoform CRA_e OS=Homo sapiens GN=WDR45 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 1.3 1.1e+02 12 38 .] 8 33 .. 2 33 .. 0.82 2 ? 9.0 0.0 0.17 14 6 34 .. 152 181 .. 147 186 .. 0.87 3 ! 16.7 0.0 0.00062 0.05 13 37 .. 205 229 .. 191 229 .. 0.84 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 1.3 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +vtsl+f++d++ ++ + + vri++ tr|C9JYH8|C9JYH8_HUMAN 8 GVTSLRFNQDQSCFC-CAMETGVRIYN 33 49***********96.55599999997 PP == domain 2 score: 9.0 bits; conditional E-value: 0.17 EEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H s++ +++ ++ g+ +as+s +gt+ tr|C9JYH8|C9JYH8_HUMAN 152 TINAHqSDIACVSLNQPGTVVASASQKGTL 181 5569*999*****************88875 PP == domain 3 score: 16.7 bits; conditional E-value: 0.00062 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ fs+d+++l+++sd+gtv+i+ tr|C9JYH8|C9JYH8_HUMAN 205 LYCINFSHDSSFLCASSDKGTVHIF 229 78************99******995 PP >> sp|Q12770|SCAP_HUMAN Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sapiens GN=SCAP P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 0.034 2.7 6 38 .] 771 802 .. 769 802 .. 0.95 2 ? 9.4 0.0 0.12 9.7 5 37 .. 1072 1104 .. 1068 1105 .. 0.72 3 ! 18.7 0.2 0.00014 0.012 2 38 .] 1110 1146 .. 1109 1146 .. 0.79 4 ? 6.3 2.0 1.2 94 5 38 .] 1155 1186 .. 1150 1186 .. 0.69 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.034 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+GH ++ +l +dg +l+s++ g+v +Wd sp|Q12770|SCAP_HUMAN 771 VLRGHlMDIECL--ASDGMLLVSCCLAGHVCVWD 802 689**999****..99*****************9 PP == domain 2 score: 9.4 bits; conditional E-value: 0.12 EEEE.SS.SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 5 rtlt.GH.ssvtslafspdgaw....lasGsdDgtvriW 37 +t +H +++t+l + l++Gs D+t+r++ sp|Q12770|SCAP_HUMAN 1072 HTVPcAHqKPITAL------KAaagrLVTGSQDHTLRVF 1104 4543489999**99......333444679********97 PP == domain 3 score: 18.7 bits; conditional E-value: 0.00014 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 cl tl GH + +t + d+++ lasG+ Dg + +Wd sp|Q12770|SCAP_HUMAN 1110 CCLFTLQGHsGAITTV--YIDQTMvLASGGQDGAICLWD 1146 599******5559999..3344444689**********9 PP == domain 4 score: 6.3 bits; conditional E-value: 1.2 EEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +++ +H ++vtsl + ++s++ D + iWd sp|Q12770|SCAP_HUMAN 1155 HVF-AHrGDVTSL------TCttscVISSGLDDLISIWD 1186 445.899999999......333343556666*******9 PP >> tr|H0Y978|H0Y978_HUMAN Intraflagellar transport protein 122 homolog (Fragment) OS=Homo sapiens GN=IFT122 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 1.2 95 13 34 .. 2 32 .. 1 34 [. 0.77 2 ! 13.0 0.0 0.0089 0.72 2 24 .. 31 54 .. 30 79 .. 0.74 3 ! 13.0 0.1 0.009 0.73 7 37 .. 144 175 .. 138 176 .. 0.79 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 1.2 EEEEEEETTSSE..EEEEET.......TSEE CS WD40 13 vtslafspdgaw..lasGsd.......Dgtv 34 ++++af pdg+ la+Gs+ Dgt+ tr|H0Y978|H0Y978_HUMAN 2 INDIAFKPDGTQliLAAGSRllvydtsDGTL 32 89**********4446898666666667776 PP == domain 2 score: 13.0 bits; conditional E-value: 0.0089 EEEEEEESSSS.EEEEEEETTSSE CS WD40 2 qclrtltGHss.vtslafspdgaw 24 ++l+ l+GH++ v+++a+ +dg w tr|H0Y978|H0Y978_HUMAN 31 TLLQPLKGHKDtVYCVAYAKDGLW 54 67899****555*****7777777 PP == domain 3 score: 13.0 bits; conditional E-value: 0.009 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ tr|H0Y978|H0Y978_HUMAN 144 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 175 444545698888*****************876 PP >> tr|C9JCY1|C9JCY1_HUMAN Syntaxin-binding protein 5-like OS=Homo sapiens GN=STXBP5L PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.58 47 21 38 .] 123 139 .. 102 139 .. 0.67 2 ? 6.7 0.0 0.89 72 8 38 .] 205 237 .. 199 237 .. 0.82 3 ? 12.6 0.1 0.012 0.98 12 38 .] 252 278 .. 242 278 .. 0.86 4 ? 10.7 0.3 0.05 4 24 38 .] 460 477 .. 406 477 .. 0.82 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.58 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +ga+++++s D t+++W+ tr|C9JCY1|C9JCY1_HUMAN 123 EGALVSASS-DDTLHLWN 139 455565556.*******8 PP == domain 2 score: 6.7 bits; conditional E-value: 0.89 ESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 ++H ++v +l+ ++g++l+ G ++gtv +Wd tr|C9JCY1|C9JCY1_HUMAN 205 KTHpGPVVHLSdsPRDEGKLLI-GYENGTVVFWD 237 6798889999987777777776.**********9 PP == domain 3 score: 12.6 bits; conditional E-value: 0.012 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++++++g+ +++++ Dg++ +W+ tr|C9JCY1|C9JCY1_HUMAN 252 AIHSIDWHHEGKQFMCSHSDGSLTLWN 278 39*************9988*******8 PP == domain 4 score: 10.7 bits; conditional E-value: 0.05 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 + +++G+ Dg++++Wd tr|C9JCY1|C9JCY1_HUMAN 460 YpeiIITGHADGSIKFWD 477 155488***********9 PP >> tr|A6NM71|A6NM71_HUMAN WD repeat domain phosphoinositide-interacting protein 4 OS=Homo sapiens GN=WDR45 PE=4 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 1.2 94 12 38 .] 8 33 .. 2 33 .. 0.82 2 ? 9.2 0.0 0.14 11 6 34 .. 85 114 .. 78 119 .. 0.86 3 ! 16.9 0.0 0.00053 0.043 13 37 .. 138 162 .. 124 162 .. 0.84 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 1.2 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +vtsl+f++d++ ++ + + vri++ tr|A6NM71|A6NM71_HUMAN 8 GVTSLRFNQDQSCFC-CAMETGVRIYN 33 49***********96.55599999997 PP == domain 2 score: 9.2 bits; conditional E-value: 0.14 EEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H s++ +++ ++ g+ +as+s +gt+ tr|A6NM71|A6NM71_HUMAN 85 TINAHqSDIACVSLNQPGTVVASASQKGTL 114 4569*999*****************88875 PP == domain 3 score: 16.9 bits; conditional E-value: 0.00053 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ fs+d+++l+++sd+gtv+i+ tr|A6NM71|A6NM71_HUMAN 138 LYCINFSHDSSFLCASSDKGTVHIF 162 78************99******995 PP >> tr|H0YAC6|H0YAC6_HUMAN Lipopolysaccharide-responsive and beige-like anchor protein (Fragment) OS=Homo sapiens GN=LRB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.1 1.6 1.3e+02 13 37 .. 1238 1265 .. 1224 1266 .. 0.73 2 ? 11.4 0.2 0.029 2.4 4 37 .. 1273 1311 .. 1270 1312 .. 0.82 3 ? 4.1 0.0 5.9 4.8e+02 5 29 .. 1333 1358 .. 1330 1364 .. 0.82 4 ? 8.2 0.0 0.29 23 10 34 .. 1421 1444 .. 1411 1447 .. 0.77 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 1.6 EEEEE..EETTSSE.EEEEETTSEEEEE CS WD40 13 vtsla..fspdgaw.lasGsdDgtvriW 37 v+s++ +d+++ l++G +D++ r++ tr|H0YAC6|H0YAC6_HUMAN 1238 VHSQCfvITSDNRYiLVCGFWDKSFRVY 1265 55555666666677256889******98 PP == domain 2 score: 11.4 bits; conditional E-value: 0.029 EEEEESSSS.EEEEE....EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtsla....fspdgawlasGsdDgtvriW 37 +++ GH + vt+la + + +++sGs+D t+ +W tr|H0YAC6|H0YAC6_HUMAN 1273 IQVVFGHWDvVTCLArsesYIGGNCYILSGSRDATLLLW 1311 566669*3358***99999888888899*********** PP == domain 3 score: 4.1 bits; conditional E-value: 5.9 EEEESSSS.EEEEEEETTSSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGs 29 +ltGH+ vt+ a++ + +++sGs tr|H0YAC6|H0YAC6_HUMAN 1333 AILTGHDYeVTCAAVCAELGLVLSGS 1358 689***447****9999999999998 PP == domain 4 score: 8.2 bits; conditional E-value: 0.29 SSSEEEEEEETTSSEEEEEETTSEE CS WD40 10 HssvtslafspdgawlasGsdDgtv 34 +++++++ s+dg++l++G+ D+ v tr|H0YAC6|H0YAC6_HUMAN 1421 DDNIRAIQLSRDGQYLLTGG-DRGV 1444 44599***************.9866 PP >> tr|F8VV53|F8VV53_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1C PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.1 0.00019 0.015 3 38 .] 17 54 .. 15 54 .. 0.83 2 ! 18.5 0.1 0.00017 0.014 10 38 .] 68 97 .. 61 97 .. 0.92 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 0.00019 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ + iW+ tr|F8VV53|F8VV53_HUMAN 17 PVVILEGHsKRVGIVAWHPTARNVLlsAGC-DNAIIIWN 54 77899***888*9999*******6332677.*******8 PP == domain 2 score: 18.5 bits; conditional E-value: 0.00017 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 Hs+ ++ ++++++g++++++s+D++vr+ d tr|F8VV53|F8VV53_HUMAN 68 HSDmIYNVSWNRNGSLICTASKDKKVRVID 97 87789**********************965 PP >> sp|Q9Y484|WIPI4_HUMAN WD repeat domain phosphoinositide-interacting protein 4 OS=Homo sapiens GN=WDR45 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 1.5 1.2e+02 12 38 .] 8 33 .. 2 33 .. 0.82 2 ? 8.8 0.0 0.19 15 6 34 .. 187 216 .. 181 221 .. 0.87 3 ! 16.5 0.0 0.00071 0.057 13 37 .. 240 264 .. 226 264 .. 0.84 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +vtsl+f++d++ ++ + + vri++ sp|Q9Y484|WIPI4_HUMAN 8 GVTSLRFNQDQSCFC-CAMETGVRIYN 33 49***********96.55599999997 PP == domain 2 score: 8.8 bits; conditional E-value: 0.19 EEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H s++ +++ ++ g+ +as+s +gt+ sp|Q9Y484|WIPI4_HUMAN 187 TINAHqSDIACVSLNQPGTVVASASQKGTL 216 4569*999*****************88875 PP == domain 3 score: 16.5 bits; conditional E-value: 0.00071 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ fs+d+++l+++sd+gtv+i+ sp|Q9Y484|WIPI4_HUMAN 240 LYCINFSHDSSFLCASSDKGTVHIF 264 78************99******995 PP >> tr|F8WDI9|F8WDI9_HUMAN Transducin beta-like protein 2 OS=Homo sapiens GN=TBL2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.7 0.2 3e-10 2.4e-08 7 38 .] 86 118 .. 74 118 .. 0.90 Alignments for each domain: == domain 1 score: 36.7 bits; conditional E-value: 3e-10 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+ H +++++++fs++g++la++ dD+t+riW+ tr|F8WDI9|F8WDI9_HUMAN 86 LKSHsGNISCMDFSSNGKYLATCADDRTIRIWS 118 6789555*************************5 PP >> tr|B4DZ46|B4DZ46_HUMAN F-box/WD repeat-containing protein 9 OS=Homo sapiens GN=FBXW9 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 1.1 89 13 38 .] 7 30 .. 2 30 .. 0.73 2 ? 6.5 0.0 1.1 85 19 36 .. 52 69 .. 38 71 .. 0.78 3 ! 13.7 0.1 0.0055 0.45 2 36 .. 117 151 .. 116 152 .. 0.75 4 ? 7.8 0.0 0.39 32 10 37 .. 166 192 .. 158 193 .. 0.81 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 1.1 EEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw....lasGsdDgtvriWd 38 v +l ++ l++G++D++v i+d tr|B4DZ46|B4DZ46_HUMAN 7 VLCL------SYlpdiLVTGTYDKKVTIYD 30 7777......44333389**99*****998 PP == domain 2 score: 6.5 bits; conditional E-value: 1.1 ETTSSEEEEEETTSEEEE CS WD40 19 spdgawlasGsdDgtvri 36 d + ++sGs+D+t+ + tr|B4DZ46|B4DZ46_HUMAN 52 LADDRHIISGSEDHTLVV 69 56778899*******987 PP == domain 3 score: 13.7 bits; conditional E-value: 0.0055 EEEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtlt.GH.ssvtslafspdgawlasGsdDgtvri 36 q++r+++ GH +++t++++s + + s D+t+r+ tr|B4DZ46|B4DZ46_HUMAN 117 QLIRSFDvGHsFPITGIQYSVGALY--TTSTDKTIRV 151 78899977**777****66666666..4455*****8 PP == domain 4 score: 7.8 bits; conditional E-value: 0.39 S.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriW 37 H ++ + + + +g+++++Gs D ++ +W tr|B4DZ46|B4DZ46_HUMAN 166 HdNGLNRV--CAEGNLVVAGSGDLSLEVW 192 76666666..779*******88******* PP >> sp|Q9Y484-3|WIPI4_HUMAN Isoform 3 of WD repeat domain phosphoinositide-interacting protein 4 OS=Homo sapiens GN=WDR4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 1.5 1.3e+02 12 38 .] 8 33 .. 2 33 .. 0.82 2 ? 8.8 0.0 0.19 16 6 34 .. 188 217 .. 182 222 .. 0.87 3 ! 16.5 0.0 0.00071 0.058 13 37 .. 241 265 .. 227 265 .. 0.84 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +vtsl+f++d++ ++ + + vri++ sp|Q9Y484-3|WIPI4_HUMAN 8 GVTSLRFNQDQSCFC-CAMETGVRIYN 33 49***********96.55599999997 PP == domain 2 score: 8.8 bits; conditional E-value: 0.19 EEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H s++ +++ ++ g+ +as+s +gt+ sp|Q9Y484-3|WIPI4_HUMAN 188 TINAHqSDIACVSLNQPGTVVASASQKGTL 217 4569*999*****************88875 PP == domain 3 score: 16.5 bits; conditional E-value: 0.00071 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ fs+d+++l+++sd+gtv+i+ sp|Q9Y484-3|WIPI4_HUMAN 241 LYCINFSHDSSFLCASSDKGTVHIF 265 78************99******995 PP >> tr|K7ELV2|K7ELV2_HUMAN Nucleoporin SEH1 (Fragment) OS=Homo sapiens GN=SEH1L PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 0.9 1.1e-05 0.00089 10 38 .] 11 40 .. 5 40 .. 0.92 2 ? 12.2 2.6 0.016 1.3 2 37 .. 48 86 .. 47 87 .. 0.85 3 ? 12.1 0.0 0.017 1.4 11 37 .. 114 142 .. 96 143 .. 0.76 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 1.1e-05 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H++ +++++f+ +g+ +a++s D++v++Wd tr|K7ELV2|K7ELV2_HUMAN 11 HKDlIHDVSFDFHGRRMATCSSDQSVKVWD 40 87789***************88*******9 PP == domain 2 score: 12.2 bits; conditional E-value: 0.016 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriW 37 c+ ++++H +sv+ + +w las+s D+t +W tr|K7ELV2|K7ELV2_HUMAN 48 HCTASWKTHsGSVWRV------TWahpefgqvLASCSFDRTAAVW 86 79999****777****......777777777799********999 PP == domain 3 score: 12.1 bits; conditional E-value: 0.017 SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 11 ssvtslafspdgaw..lasGsdDgtvriW 37 +svt+++f p + la++s Dg vri+ tr|K7ELV2|K7ELV2_HUMAN 114 TSVTDVKFAPKHMGlmLATCSADGIVRIY 142 459999766665555579**********8 PP >> sp|Q9Y484-2|WIPI4_HUMAN Isoform 2 of WD repeat domain phosphoinositide-interacting protein 4 OS=Homo sapiens GN=WDR4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 1.6 1.3e+02 12 38 .] 8 33 .. 2 33 .. 0.82 2 ? 8.7 0.0 0.2 16 6 34 .. 198 227 .. 192 232 .. 0.87 3 ! 16.4 0.0 0.00074 0.06 13 37 .. 251 275 .. 237 275 .. 0.84 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 1.6 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +vtsl+f++d++ ++ + + vri++ sp|Q9Y484-2|WIPI4_HUMAN 8 GVTSLRFNQDQSCFC-CAMETGVRIYN 33 49***********96.55599999997 PP == domain 2 score: 8.7 bits; conditional E-value: 0.2 EEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H s++ +++ ++ g+ +as+s +gt+ sp|Q9Y484-2|WIPI4_HUMAN 198 TINAHqSDIACVSLNQPGTVVASASQKGTL 227 4569*999*****************88875 PP == domain 3 score: 16.4 bits; conditional E-value: 0.00074 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ fs+d+++l+++sd+gtv+i+ sp|Q9Y484-2|WIPI4_HUMAN 251 LYCINFSHDSSFLCASSDKGTVHIF 275 78************99******995 PP >> tr|H0YJX1|H0YJX1_HUMAN Echinoderm microtubule-associated protein-like 5 (Fragment) OS=Homo sapiens GN=EML5 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 0.0 0.36 29 2 25 .. 29 49 .. 25 54 .. 0.83 2 ? 6.9 0.2 0.75 61 11 37 .. 102 128 .. 74 129 .. 0.75 3 ! 27.0 1.9 3.5e-07 2.8e-05 3 38 .] 138 175 .. 136 175 .. 0.87 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.36 EEEEEEESSSSEEEEEEETTSSEE CS WD40 2 qclrtltGHssvtslafspdgawl 25 +cl++l+ ++t+l++s+d+++l tr|H0YJX1|H0YJX1_HUMAN 29 ECLGSLS---FITHLDWSSDSRYL 49 5666666...8**********996 PP == domain 2 score: 6.9 bits; conditional E-value: 0.75 SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 11 ssvtslafspdgaw....lasGsdDgtvriW 37 ++++s+ dg++ l++++d g ++++ tr|H0YJX1|H0YJX1_HUMAN 102 NDINSV----DGNYigqvLVTADDYGIIKLF 128 346677....6666555589**99****997 PP == domain 3 score: 27.0 bits; conditional E-value: 3.5e-07 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriWd 38 + r++ GH +vt +++s+d +w++s G+ D++v W+ tr|H0YJX1|H0YJX1_HUMAN 138 KFRKYIGHsAHVTNVRWSHDYQWVISiGGADHSVFQWK 175 57899***777************9755888*******5 PP >> tr|K7ENI5|K7ENI5_HUMAN Nucleoporin SEH1 (Fragment) OS=Homo sapiens GN=SEH1L PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.9 5e-06 0.0004 10 38 .] 11 40 .. 5 40 .. 0.92 2 ! 13.0 0.0 0.009 0.73 11 37 .. 65 93 .. 54 94 .. 0.76 3 ? 5.6 0.7 1.9 1.6e+02 13 32 .. 116 140 .. 102 141 .. 0.75 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 5e-06 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H++ +++++f+ +g+ +a++s D++v++Wd tr|K7ENI5|K7ENI5_HUMAN 11 HKDlIHDVSFDFHGRRMATCSSDQSVKVWD 40 87789***************88*******9 PP == domain 2 score: 13.0 bits; conditional E-value: 0.009 SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 11 ssvtslafspdgaw..lasGsdDgtvriW 37 +svt+++f p + la++s Dg vri+ tr|K7ENI5|K7ENI5_HUMAN 65 TSVTDVKFAPKHMGlmLATCSADGIVRIY 93 469999766665555579**********8 PP == domain 3 score: 5.6 bits; conditional E-value: 1.9 EEEEEEETTSSE.....EEEEETTS CS WD40 13 vtslafspdgaw.....lasGsdDg 32 ++++++p+++ +a GsdD tr|K7ENI5|K7ENI5_HUMAN 116 CSCISWNPSSSRahspmIAVGSDDS 140 57999***999999998889**885 PP >> tr|H3BR95|H3BR95_HUMAN WD repeat-containing protein 59 (Fragment) OS=Homo sapiens GN=WDR59 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 4.7 3.8e+02 7 31 .. 27 61 .. 22 69 .. 0.71 2 ! 18.5 0.2 0.00016 0.013 4 38 .] 77 113 .. 74 113 .. 0.85 3 ! 15.3 0.2 0.0017 0.14 20 38 .] 138 155 .. 121 155 .. 0.75 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 4.7 EESS.SS.......EEEEEEETTSSE...EEEEETT CS WD40 7 ltGH.ss.......vtslafspdgaw...lasGsdD 31 ++GH + + +++++p+ ++ +a++s + tr|H3BR95|H3BR95_HUMAN 27 FEGHrKIsrqskwdIGAVQWNPHDSFahyFAASS-N 61 7899633446667788888999999976667666.5 PP == domain 2 score: 18.5 bits; conditional E-value: 0.00016 EEEEESSSS.EEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgaw.......lasGsdDgtvriWd 38 +tl GH+ +++l +w l+++s D ++iWd tr|H3BR95|H3BR95_HUMAN 77 GTTLQGHTRvISDL------DWavfepdlLVTSSVDTYIYIWD 113 5789***7767***......8888888888899*********9 PP == domain 3 score: 15.3 bits; conditional E-value: 0.0017 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 ++ + la+++ Dg vriWd tr|H3BR95|H3BR95_HUMAN 138 KNANCLATSH-DGDVRIWD 155 3455588888.*******9 PP >> tr|F8W9K4|F8W9K4_HUMAN WD repeat-containing protein 48 OS=Homo sapiens GN=WDR48 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.0 0.0056 0.45 11 38 .] 31 58 .. 24 58 .. 0.89 2 ! 21.3 0.7 2.1e-05 0.0017 7 38 .] 71 103 .. 65 103 .. 0.81 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.0056 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v++l+ +p + l+++++D +riW+ tr|F8W9K4|F8W9K4_HUMAN 31 NGVNALQLDPALNRLFTAGRDSIIRIWS 58 56999999999999*99999*******5 PP == domain 2 score: 21.3 bits; conditional E-value: 2.1e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H ++v+++ + +g+ l+s+s D tv++W+ tr|F8W9K4|F8W9K4_HUMAN 71 MEHHtDWVNDIVLCCNGKTLISASSDTTVKVWN 103 566866688777777*****99988*******8 PP >> sp|Q96MX6-2|WDR92_HUMAN Isoform 2 of WD repeat-containing protein 92 OS=Homo sapiens GN=WDR92 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 2.5 2e+02 21 38 .] 79 96 .. 66 96 .. 0.85 2 ! 21.7 0.0 1.5e-05 0.0013 3 38 .] 103 145 .. 101 145 .. 0.74 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 2.5 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +++la+G+ g+++iW+ sp|Q96MX6-2|WDR92_HUMAN 79 QQRYLATGDFGGNLHIWN 96 5689****99*******8 PP == domain 2 score: 21.7 bits; conditional E-value: 1.5e-05 EEEEEESSSS.EEEEE......EETTSSE.....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtsla......fspdgaw.....lasGsdDgtvriWd 38 ++++ +GH+ +++++ +++Gs+Dgtv++Wd sp|Q96MX6-2|WDR92_HUMAN 103 PVYSVKGHKEiINAIDgigglgI-----GegapeIVTGSRDGTVKVWD 145 688999**7757*9955555543.....05555599***********9 PP >> tr|J3KTR0|J3KTR0_HUMAN Cirhin (Fragment) OS=Homo sapiens GN=CIRH1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 0.00092 0.075 12 37 .. 20 45 .. 12 46 .. 0.89 2 ? 12.5 0.0 0.013 1.1 11 31 .. 63 83 .. 53 86 .. 0.80 3 ? 5.8 0.3 1.7 1.3e+02 13 38 .] 115 139 .. 104 139 .. 0.82 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 0.00092 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +++s+a sp+g+ l+ G++Dg+v+++ tr|J3KTR0|J3KTR0_HUMAN 20 PIWSMAASPSGSQLLVGCEDGSVKLF 45 59**********************97 PP == domain 2 score: 12.5 bits; conditional E-value: 0.013 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 s + sl+++p+g+ +a+Gs D tr|J3KTR0|J3KTR0_HUMAN 63 SRILSLSWHPSGTHIAAGSID 83 4499**************966 PP == domain 3 score: 5.8 bits; conditional E-value: 1.7 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v+++af +dg+ ++ s g+v +Wd tr|J3KTR0|J3KTR0_HUMAN 115 VWGVAFLSDGTIISVDS-AGKVQFWD 139 7***********86446.99999998 PP >> tr|G3V4B8|G3V4B8_HUMAN WD repeat-containing protein 89 (Fragment) OS=Homo sapiens GN=WDR89 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 8.2 6.6e+02 26 38 .] 46 56 .. 29 56 .. 0.82 2 ! 14.9 0.1 0.0023 0.18 3 38 .] 62 98 .. 60 98 .. 0.79 3 ! 18.1 0.1 0.00022 0.018 9 38 .] 168 199 .. 159 199 .. 0.82 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.2 EEEETTSEEEEEE CS WD40 26 asGsdDgtvriWd 38 + +s +g++ri+d tr|G3V4B8|G3V4B8_HUMAN 46 L-CS-NGSIRIYD 56 2.89.*******8 PP == domain 2 score: 14.9 bits; conditional E-value: 0.0023 EEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss..vtslafspdgawlasGsdDgtvriWd 38 lr+++G + ++++f + + + s++ Dgtv+ Wd tr|G3V4B8|G3V4B8_HUMAN 62 VLREFSGY-PglLNGVRFANSCDSVYSACTDGTVKCWD 98 57888888.334789988888888887777*******9 PP == domain 3 score: 18.1 bits; conditional E-value: 0.00022 SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +H ++vt ++f+p+++ ++sGs Dg v ++d tr|G3V4B8|G3V4B8_HUMAN 168 THsDDVTQVRFHPSNPNmVVSGSSDGLVNVFD 199 89666************4469988****9998 PP >> tr|D6RBG7|D6RBG7_HUMAN Coatomer subunit beta' (Fragment) OS=Homo sapiens GN=COPB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.0 0.0052 0.42 13 38 .] 31 56 .. 18 56 .. 0.80 2 ! 17.1 0.0 0.00045 0.036 3 29 .. 62 89 .] 60 89 .] 0.88 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.0052 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v++ +f ++w+++G dD +r+++ tr|D6RBG7|D6RBG7_HUMAN 31 VRAAKFVARKNWVVTGADDMQIRVFN 56 7777799999**************97 PP == domain 2 score: 17.1 bits; conditional E-value: 0.00045 EEEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGs 29 ++ +++Hs+ ++++a++p +++++++s tr|D6RBG7|D6RBG7_HUMAN 62 RVHMFEAHSDyIRCIAVHPTQPFILTSS 89 5899****556*************9987 PP >> tr|E9PFI2|E9PFI2_HUMAN Syntaxin-binding protein 5-like OS=Homo sapiens GN=STXBP5L PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.66 54 21 38 .] 123 139 .. 102 139 .. 0.67 2 ? 6.5 0.0 1 84 8 38 .] 205 237 .. 199 237 .. 0.82 3 ? 12.4 0.1 0.014 1.1 12 38 .] 252 278 .. 242 278 .. 0.86 4 ? 10.4 0.3 0.059 4.8 24 38 .] 460 477 .. 406 477 .. 0.82 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.66 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +ga+++++s D t+++W+ tr|E9PFI2|E9PFI2_HUMAN 123 EGALVSASS-DDTLHLWN 139 455565556.*******8 PP == domain 2 score: 6.5 bits; conditional E-value: 1 ESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 ++H ++v +l+ ++g++l+ G ++gtv +Wd tr|E9PFI2|E9PFI2_HUMAN 205 KTHpGPVVHLSdsPRDEGKLLI-GYENGTVVFWD 237 6798889999987777777776.**********9 PP == domain 3 score: 12.4 bits; conditional E-value: 0.014 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++++++g+ +++++ Dg++ +W+ tr|E9PFI2|E9PFI2_HUMAN 252 AIHSIDWHHEGKQFMCSHSDGSLTLWN 278 39*************9988*******8 PP == domain 4 score: 10.4 bits; conditional E-value: 0.059 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 + +++G+ Dg++++Wd tr|E9PFI2|E9PFI2_HUMAN 460 YpeiIITGHADGSIKFWD 477 155488***********9 PP >> tr|B4DEY9|B4DEY9_HUMAN Intraflagellar transport protein 122 homolog OS=Homo sapiens GN=IFT122 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.0 0.73 59 10 34 .. 13 45 .. 4 47 .. 0.77 2 ? 9.4 0.3 0.12 10 3 29 .. 45 92 .. 43 113 .. 0.62 3 ? 10.9 0.1 0.042 3.4 7 37 .. 211 242 .. 205 243 .. 0.79 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.73 SSSEEEEEEETTSSE..EEEEET.......TSEE CS WD40 10 Hssvtslafspdgaw..lasGsd.......Dgtv 34 H +++++af pdg+ la+Gs+ Dgt+ tr|B4DEY9|B4DEY9_HUMAN 13 H-CINDIAFKPDGTQliLAAGSRllvydtsDGTL 45 6.7************4446898666666667776 PP == domain 2 score: 9.4 bits; conditional E-value: 0.12 EEEEEESSSS.EEEEE...........EETTSSE.........EEEEE CS WD40 3 clrtltGHss.vtsla...........fspdgaw.........lasGs 29 +l+ l+GH++ v+++a +sp+++ ++++s tr|B4DEY9|B4DEY9_HUMAN 45 LLQPLKGHKDtVYCVAyakdvlcieglWSPEQKSvskhkssskIICCS 92 677888994458888888888888888666666533333333333344 PP == domain 3 score: 10.9 bits; conditional E-value: 0.042 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ tr|B4DEY9|B4DEY9_HUMAN 211 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 242 444545698888*****************876 PP >> tr|H0YEI6|H0YEI6_HUMAN WD and tetratricopeptide repeats protein 1 (Fragment) OS=Homo sapiens GN=WDTC1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.1 0.19 15 25 37 .. 1 13 [. 1 14 [. 0.91 2 ! 25.7 0.0 9e-07 7.3e-05 2 38 .] 19 56 .. 18 56 .. 0.91 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.19 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 ++sGsdDg+ iW tr|H0YEI6|H0YEI6_HUMAN 1 IVSGSDDGSFFIW 13 589********** PP == domain 2 score: 25.7 bits; conditional E-value: 9e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++r+l G s v++l+ +p+ +la+++ D+ vr+W+ tr|H0YEI6|H0YEI6_HUMAN 19 NLVRVLQGDeSIVNCLQPHPSYCFLATSGIDPVVRLWN 56 5789999995558************************8 PP >> sp|Q9Y2K9|STB5L_HUMAN Syntaxin-binding protein 5-like OS=Homo sapiens GN=STXBP5L PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.68 55 21 38 .] 123 139 .. 102 139 .. 0.67 2 ? 6.5 0.0 1.1 86 8 38 .] 205 237 .. 199 237 .. 0.82 3 ? 12.4 0.1 0.014 1.2 12 38 .] 252 278 .. 242 278 .. 0.86 4 ? 10.4 0.3 0.06 4.9 24 38 .] 460 477 .. 406 477 .. 0.82 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.68 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +ga+++++s D t+++W+ sp|Q9Y2K9|STB5L_HUMAN 123 EGALVSASS-DDTLHLWN 139 455565556.*******8 PP == domain 2 score: 6.5 bits; conditional E-value: 1.1 ESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 ++H ++v +l+ ++g++l+ G ++gtv +Wd sp|Q9Y2K9|STB5L_HUMAN 205 KTHpGPVVHLSdsPRDEGKLLI-GYENGTVVFWD 237 6798889999987777777776.**********9 PP == domain 3 score: 12.4 bits; conditional E-value: 0.014 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s++++++g+ +++++ Dg++ +W+ sp|Q9Y2K9|STB5L_HUMAN 252 AIHSIDWHHEGKQFMCSHSDGSLTLWN 278 39*************9988*******8 PP == domain 4 score: 10.4 bits; conditional E-value: 0.06 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 + +++G+ Dg++++Wd sp|Q9Y2K9|STB5L_HUMAN 460 YpeiIITGHADGSIKFWD 477 155488***********9 PP >> tr|D6RH33|D6RH33_HUMAN WD repeat-containing protein 41 (Fragment) OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 0.0016 0.13 4 38 .] 28 62 .. 25 62 .. 0.78 2 ! 17.6 0.0 0.00031 0.025 2 38 .] 67 111 .. 66 111 .. 0.73 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0016 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l++H + v+ l +d ++ as++dDg v +W+ tr|D6RH33|D6RH33_HUMAN 28 LLVLKAHhDIVRFLVQLDDYRF-ASAGDDGIVVVWN 62 6789999444788888888888.67777*******8 PP == domain 2 score: 17.6 bits; conditional E-value: 0.00031 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd tr|D6RH33|D6RH33_HUMAN 67 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 111 6788999**7779999855555544444444779999*******9 PP >> tr|D6RBY6|D6RBY6_HUMAN WD repeat-containing protein 41 (Fragment) OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 0.0021 0.17 4 38 .] 31 65 .. 28 65 .. 0.78 2 ! 17.2 0.0 0.00043 0.035 2 38 .] 70 114 .. 69 114 .. 0.73 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 0.0021 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l++H + v+ l +d ++ as++dDg v +W+ tr|D6RBY6|D6RBY6_HUMAN 31 LLVLKAHhDIVRFLVQLDDYRF-ASAGDDGIVVVWN 65 6789999444788888888888.67777*******8 PP == domain 2 score: 17.2 bits; conditional E-value: 0.00043 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd tr|D6RBY6|D6RBY6_HUMAN 70 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 114 6788999**7779999855555544444444779999*******9 PP >> tr|J3KTP2|J3KTP2_HUMAN WD repeat-containing protein WRAP73 (Fragment) OS=Homo sapiens GN=WRAP73 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 1.9 1.6e+02 1 26 [. 102 128 .. 102 142 .. 0.85 2 ! 24.7 0.0 1.8e-06 0.00015 2 36 .. 146 183 .. 145 185 .. 0.84 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 1.9 TEEEEEEESS.SSEEEEEEETTSSEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawla 26 +q+lr++++ ++ t++ + p+g la tr|J3KTP2|J3KTP2_HUMAN 102 WQLLRHFDTDtQDLTGIEWAPNGCVLA 128 6899999988788**********9986 PP == domain 2 score: 24.7 bits; conditional E-value: 1.8e-06 EEEEEEESSSS...EEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGHss...vtslafspdgawlasGsdDgtvri 36 ++l t+++ + + s+a+sp++++la Gs+Dg+vri tr|J3KTP2|J3KTP2_HUMAN 146 RLLSTYSAYEWslgIKSVAWSPSSQFLAVGSYDGKVRI 183 567788877334779**********************9 PP >> tr|B4DHS8|B4DHS8_HUMAN WD repeat-containing protein 41 OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 0.0021 0.17 4 38 .] 36 70 .. 33 70 .. 0.78 2 ! 17.2 0.0 0.00042 0.034 2 38 .] 75 119 .. 74 119 .. 0.73 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 0.0021 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l++H + v+ l +d ++ as++dDg v +W+ tr|B4DHS8|B4DHS8_HUMAN 36 LLVLKAHhDIVRFLVQLDDYRF-ASAGDDGIVVVWN 70 6789999444788888888888.67777*******8 PP == domain 2 score: 17.2 bits; conditional E-value: 0.00042 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd tr|B4DHS8|B4DHS8_HUMAN 75 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 119 6788999**7779999855555544444444779999*******9 PP >> tr|B4E2L4|B4E2L4_HUMAN WD repeat-containing protein 41 OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.0 5.2e-06 0.00042 3 37 .. 63 95 .. 61 96 .. 0.88 2 ? 10.6 0.1 0.051 4.1 3 38 .] 143 178 .. 141 178 .. 0.76 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 5.2e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++t +H s+v ++a p+ +++ s+s+Dg+vriW tr|B4E2L4|B4E2L4_HUMAN 63 CQKT--AHdSNVLHVARLPNRQLI-SCSEDGSVRIW 95 6777..9*777************7.7999******* PP == domain 2 score: 10.6 bits; conditional E-value: 0.051 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ l GH ssv + + d+ ++ ++s D+ + +W+ tr|B4E2L4|B4E2L4_HUMAN 143 LIGDLIGHsSSVEMFLYFEDHGLV-TCSADHLIILWK 178 567789**7779666566666665.7888*******6 PP >> tr|D6RB94|D6RB94_HUMAN WD repeat-containing protein 41 OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 0.0016 0.13 4 38 .] 36 70 .. 33 70 .. 0.78 2 ! 17.6 0.0 0.00031 0.025 2 38 .] 75 119 .. 74 119 .. 0.73 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0016 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l++H + v+ l +d ++ as++dDg v +W+ tr|D6RB94|D6RB94_HUMAN 36 LLVLKAHhDIVRFLVQLDDYRF-ASAGDDGIVVVWN 70 6789999444788888888888.67777*******8 PP == domain 2 score: 17.6 bits; conditional E-value: 0.00031 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd tr|D6RB94|D6RB94_HUMAN 75 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 119 6788999**7779999855555544444444779999*******9 PP >> tr|C9J4Z7|C9J4Z7_HUMAN Actin-related protein 2/3 complex subunit 1B (Fragment) OS=Homo sapiens GN=ARPC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.2 6.1e-07 4.9e-05 2 37 .. 43 79 .. 42 80 .. 0.91 2 ? 4.3 0.0 4.9 4e+02 14 33 .. 100 119 .. 89 122 .. 0.82 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 6.1e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +++++l+ H++ vt++++ p+++ +++++ D++ ++W tr|C9J4Z7|C9J4Z7_HUMAN 43 TKVHELKEHNGqVTGIDWAPESNRIVTCGTDRNAYVW 79 689******555**************9999******* PP == domain 2 score: 4.3 bits; conditional E-value: 4.9 EEEEEETTSSEEEEEETTSE CS WD40 14 tslafspdgawlasGsdDgt 33 +++++ p+ + +a Gs + tr|C9J4Z7|C9J4Z7_HUMAN 100 RCVRWAPNENKFAVGSGSRV 119 69**********99975555 PP >> sp|Q9Y5J1|UTP18_HUMAN U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens GN=UTP18 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7.4 6e+02 12 36 .. 249 277 .. 237 279 .. 0.75 2 ? 10.7 0.0 0.047 3.8 17 38 .] 386 410 .. 368 410 .. 0.78 3 ? 7.7 0.0 0.44 35 15 38 .] 430 453 .. 415 453 .. 0.86 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.4 S....EEEEEEETTSSEEEEEETTSEEEE CS WD40 12 s....vtslafspdgawlasGsdDgtvri 36 + ++s++f+p + ++ ++ D+ v + sp|Q9Y5J1|UTP18_HUMAN 249 PtvarISSVQFHPGAQIVMVAGLDNAVSL 277 1555599**********986776998877 PP == domain 2 score: 10.7 bits; conditional E-value: 0.047 E...EETTSSEEEEEETTSEEEEEE CS WD40 17 a...fspdgawlasGsdDgtvriWd 38 a fs+d++ + ++s Dg v++Wd sp|Q9Y5J1|UTP18_HUMAN 386 AastFSSDSKKVYASSGDGEVYVWD 410 244599*****976666*******9 PP == domain 3 score: 7.7 bits; conditional E-value: 0.44 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 s+a+s++g+++a+Gs g v i++ sp|Q9Y5J1|UTP18_HUMAN 430 SIATSRNGQYVACGSNCGVVNIYN 453 688************888888876 PP >> sp|Q9BYB4-2|GNB1L_HUMAN Isoform 2 of Guanine nucleotide-binding protein subunit beta-like protein 1 OS=Homo sapiens # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.0 0.093 7.6 3 38 .] 12 53 .. 10 53 .. 0.78 2 ? 11.6 0.0 0.026 2.1 4 38 .] 60 96 .. 57 96 .. 0.87 3 ? 11.1 0.0 0.036 2.9 21 38 .] 177 194 .. 147 194 .. 0.80 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.093 EEEEEESS.SSEEEEEEETTSSE...........EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw...........lasGsdDgtvriWd 38 ++ +l+G s+v++l + l+sGs g v+iW+ sp|Q9BYB4-2|GNB1L_HUMAN 12 PQFVLRGTqSPVHALH------FcegaqaqgrplLFSGSQSGLVHIWS 53 78899999888*9995......44444447777689***********5 PP == domain 2 score: 11.6 bits; conditional E-value: 0.026 EEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 ++tl+GH ++vt l++ p g+ l+s ++D ++ +Wd sp|Q9BYB4-2|GNB1L_HUMAN 60 VTTLDGHggQCVTWLQTLPQGRQLLSQGRDLKLCLWD 96 789****6444**************7688*******9 PP == domain 3 score: 11.1 bits; conditional E-value: 0.036 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 + ++l++G +Dg+v +Wd sp|Q9BYB4-2|GNB1L_HUMAN 177 SRPLLLAGYEDGSVVLWD 194 4566889**********9 PP >> tr|D6R9E7|D6R9E7_HUMAN WD repeat-containing protein 41 (Fragment) OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 0.0016 0.13 4 38 .] 33 67 .. 30 67 .. 0.78 2 ! 17.6 0.0 0.00031 0.025 2 38 .] 72 116 .. 71 116 .. 0.73 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.0016 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l++H + v+ l +d ++ as++dDg v +W+ tr|D6R9E7|D6R9E7_HUMAN 33 LLVLKAHhDIVRFLVQLDDYRF-ASAGDDGIVVVWN 67 6789999444788888888888.67777*******8 PP == domain 2 score: 17.6 bits; conditional E-value: 0.00031 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd tr|D6R9E7|D6R9E7_HUMAN 72 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 116 6788999**7779999855555544444444779999*******9 PP >> tr|C9JEY1|C9JEY1_HUMAN Actin-related protein 2/3 complex subunit 1B (Fragment) OS=Homo sapiens GN=ARPC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.2 6.3e-07 5.1e-05 2 37 .. 43 79 .. 42 80 .. 0.91 2 ? 4.3 0.0 5 4.1e+02 14 33 .. 100 119 .. 89 122 .. 0.82 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 6.3e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +++++l+ H++ vt++++ p+++ +++++ D++ ++W tr|C9JEY1|C9JEY1_HUMAN 43 TKVHELKEHNGqVTGIDWAPESNRIVTCGTDRNAYVW 79 689******555**************9999******* PP == domain 2 score: 4.3 bits; conditional E-value: 5 EEEEEETTSSEEEEEETTSE CS WD40 14 tslafspdgawlasGsdDgt 33 +++++ p+ + +a Gs + tr|C9JEY1|C9JEY1_HUMAN 100 RCVRWAPNENKFAVGSGSRV 119 69**********99975555 PP >> tr|B4E3S0|B4E3S0_HUMAN Coronin OS=Homo sapiens GN=CORO1C PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.1 0.0011 0.09 3 38 .] 17 54 .. 15 54 .. 0.83 2 ! 16.1 0.2 0.00094 0.076 10 38 .] 68 97 .. 62 97 .. 0.92 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0011 EEEEEESS.SSEEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla..sGsdDgtvriWd 38 ++ +l+GH + v +a++p + ++ +G+ D+ + iW+ tr|B4E3S0|B4E3S0_HUMAN 17 PVVILEGHsKRVGIVAWHPTARNVLlsAGC-DNAIIIWN 54 77899***888*9999*******6332677.*******8 PP == domain 2 score: 16.1 bits; conditional E-value: 0.00094 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 Hs+ ++ ++++++g++++++s+D++vr+ d tr|B4E3S0|B4E3S0_HUMAN 68 HSDmIYNVSWNRNGSLICTASKDKKVRVID 97 86789**********************965 PP >> tr|D6R9F7|D6R9F7_HUMAN Mitogen-activated protein kinase-binding protein 1 (Fragment) OS=Homo sapiens GN=MAPKBP1 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.2 2.4e-05 0.0019 9 38 .] 83 120 .. 75 120 .. 0.73 2 ? 12.3 0.0 0.015 1.3 4 29 .. 127 153 .. 125 156 .] 0.80 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 2.4e-05 SS..SS....EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 9 GH..ss....vtslafspdgawlasG..sdDgtvriWd 38 H +s +t+lafspdg++l++G + + vr+Wd tr|D6R9F7|D6R9F7_HUMAN 83 HHilNSsrktITALAFSPDGKYLVTGesGHMPAVRVWD 120 3455334666**************98754588888887 PP == domain 2 score: 12.3 bits; conditional E-value: 0.015 EEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGs 29 + +l H+ v ++afsp+ ++++s + tr|D6R9F7|D6R9F7_HUMAN 127 VAELQEHKYgVACVAFSPSAKYIVSVG 153 5678899555************99755 PP >> tr|K7EMB8|K7EMB8_HUMAN WD repeat-containing protein 7 (Fragment) OS=Homo sapiens GN=WDR7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.4 0.00027 0.022 9 38 .] 19 47 .. 14 47 .. 0.90 2 ! 16.7 0.0 0.00059 0.048 9 38 .] 62 95 .. 54 95 .. 0.92 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 0.00027 SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriWd 38 +H +++++ +dga +++G+ Dg + +Wd tr|K7EMB8|K7EMB8_HUMAN 19 TH-CISAVLLTDDGATIVTGCHDGQICLWD 47 47.7899999**********99*******9 PP == domain 2 score: 16.7 bits; conditional E-value: 0.00059 SS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriWd 38 GH s+t+l+ s+d+++++s+s+ g +Wd tr|K7EMB8|K7EMB8_HUMAN 62 GHtASITCLSkacASSDKQYIVSASESGEMCLWD 95 9*888****************************9 PP >> sp|Q6ZS30-1|NBEL1_HUMAN Isoform 1 of Neurobeachin-like protein 1 OS=Homo sapiens GN=NBEAL1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.7 8.2e-05 0.0066 4 37 .. 2365 2399 .. 2362 2400 .. 0.85 2 ? 11.6 0.0 0.025 2 2 36 .. 2414 2449 .. 2413 2450 .. 0.90 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 8.2e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + ++ H + vt+la++ g l+sGs+D t++iW sp|Q6ZS30-1|NBEL1_HUMAN 2365 ISHIIRHmDIVTCLATDYCGIHLISGSRDTTCMIW 2399 55666696669************************ PP == domain 2 score: 11.6 bits; conditional E-value: 0.025 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++ ++l GH + v s+ s + ++ +sGs+Dgtv i sp|Q6ZS30-1|NBEL1_HUMAN 2414 KPFQILYGHtNEVLSVGISTELDMAVSGSRDGTVII 2449 6788999**9889999999999***********976 PP >> sp|Q5VTH9|WDR78_HUMAN WD repeat-containing protein 78 OS=Homo sapiens GN=WDR78 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.4 0.013 1.1 2 37 .. 695 732 .. 694 733 .. 0.79 2 ? 12.2 0.0 0.016 1.3 12 38 .] 748 775 .. 738 775 .. 0.84 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 EEEEEEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.......lasGsdDgtvriW 37 q l t++GH ++v+ + +w ++s+s D v iW sp|Q5VTH9|WDR78_HUMAN 695 QYLDTYRGHkGPVYKV------TWnpfchdvFLSCSADWGVIIW 732 6789*****777****......555555555579999******* PP == domain 2 score: 12.2 bits; conditional E-value: 0.016 S.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriWd 38 s v+++a+sp +++++++ + v iWd sp|Q5VTH9|WDR78_HUMAN 748 SvVYDVAWSPKSSYIFAAANENRVEIWD 775 447************98988*******9 PP >> tr|D6RE66|D6RE66_HUMAN WD repeat-containing protein 41 (Fragment) OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 0.0023 0.19 4 38 .] 36 70 .. 33 70 .. 0.78 2 ! 17.0 0.0 0.00047 0.038 2 38 .] 75 119 .. 74 119 .. 0.73 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 0.0023 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l++H + v+ l +d ++ as++dDg v +W+ tr|D6RE66|D6RE66_HUMAN 36 LLVLKAHhDIVRFLVQLDDYRF-ASAGDDGIVVVWN 70 6789999444788888888888.67777*******8 PP == domain 2 score: 17.0 bits; conditional E-value: 0.00047 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd tr|D6RE66|D6RE66_HUMAN 75 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 119 6788999**7779999855555544444444779999*******9 PP >> tr|F5H0F7|F5H0F7_HUMAN Proteasomal ATPase-associated factor 1 (Fragment) OS=Homo sapiens GN=PAAF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.044 3.5 18 38 .] 6 26 .. 4 26 .. 0.92 2 ! 23.2 0.2 5.5e-06 0.00045 2 38 .] 31 68 .. 30 68 .. 0.87 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.044 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 f p+g ++sG++D ++iW+ tr|F5H0F7|F5H0F7_HUMAN 6 FFPSGLVVLSGGMDAQLKIWS 26 78999999************5 PP == domain 2 score: 23.2 bits; conditional E-value: 5.5e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ t++GH +++ + a + g+ ++s+s+Dgt r+Wd tr|F5H0F7|F5H0F7_HUMAN 31 SCVVTFKGHkGGILDTAIVDRGRNVVSASRDGTARLWD 68 6999*****777977777888888899**********9 PP >> tr|B4DK73|B4DK73_HUMAN WD repeat-containing protein 41 OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 0.0017 0.14 4 38 .] 36 70 .. 33 70 .. 0.78 2 ! 17.5 0.0 0.00034 0.027 2 38 .] 75 119 .. 74 119 .. 0.73 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 0.0017 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l++H + v+ l +d ++ as++dDg v +W+ tr|B4DK73|B4DK73_HUMAN 36 LLVLKAHhDIVRFLVQLDDYRF-ASAGDDGIVVVWN 70 6789999444788888888888.67777*******8 PP == domain 2 score: 17.5 bits; conditional E-value: 0.00034 EEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++l +l GH + +t++ +++++++s D+tv +Wd tr|B4DK73|B4DK73_HUMAN 75 EKLLELNGHtQKITAIItfpslesCEEKNQLILTASADRTVIVWD 119 6788999**7779999855555544444444779999*******9 PP >> tr|I3L1M1|I3L1M1_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.7 0.1 2.7e-09 2.1e-07 4 37 .. 70 105 .. 67 106 .. 0.88 Alignments for each domain: == domain 1 score: 33.7 bits; conditional E-value: 2.7e-09 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriW 37 + +l Hs+ vt+l+fsp ++l a+Gs D+tv++W tr|I3L1M1|I3L1M1_HUMAN 70 VAHLGCHSDlVTDLDFSPFDDFLlATGSADRTVKLW 105 679999*8889***********7369********** PP >> sp|Q6ZS30|NBEL1_HUMAN Neurobeachin-like protein 1 OS=Homo sapiens GN=NBEAL1 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.7 8.5e-05 0.0069 4 37 .. 2434 2468 .. 2431 2469 .. 0.85 2 ? 11.6 0.0 0.026 2.1 2 36 .. 2483 2518 .. 2482 2519 .. 0.90 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 8.5e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + ++ H + vt+la++ g l+sGs+D t++iW sp|Q6ZS30|NBEL1_HUMAN 2434 ISHIIRHmDIVTCLATDYCGIHLISGSRDTTCMIW 2468 55666696669************************ PP == domain 2 score: 11.6 bits; conditional E-value: 0.026 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++ ++l GH + v s+ s + ++ +sGs+Dgtv i sp|Q6ZS30|NBEL1_HUMAN 2483 KPFQILYGHtNEVLSVGISTELDMAVSGSRDGTVII 2518 6788999**9889999999999***********976 PP >> tr|C9J6C8|C9J6C8_HUMAN Actin-related protein 2/3 complex subunit 1B (Fragment) OS=Homo sapiens GN=ARPC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 0.2 6.6e-07 5.3e-05 2 37 .. 43 79 .. 42 80 .. 0.91 2 ? 4.3 0.0 5.1 4.1e+02 14 33 .. 100 119 .. 89 123 .. 0.83 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 6.6e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +++++l+ H++ vt++++ p+++ +++++ D++ ++W tr|C9J6C8|C9J6C8_HUMAN 43 TKVHELKEHNGqVTGIDWAPESNRIVTCGTDRNAYVW 79 689******555**************9999******* PP == domain 2 score: 4.3 bits; conditional E-value: 5.1 EEEEEETTSSEEEEEETTSE CS WD40 14 tslafspdgawlasGsdDgt 33 +++++ p+ + +a Gs + tr|C9J6C8|C9J6C8_HUMAN 100 RCVRWAPNENKFAVGSGSRV 119 69**********99975555 PP >> tr|C9JFG9|C9JFG9_HUMAN Actin-related protein 2/3 complex subunit 1B (Fragment) OS=Homo sapiens GN=ARPC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 0.2 6.6e-07 5.3e-05 2 37 .. 43 79 .. 42 80 .. 0.91 2 ? 4.3 0.0 5.1 4.1e+02 14 33 .. 100 119 .. 89 123 .. 0.83 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 6.6e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +++++l+ H++ vt++++ p+++ +++++ D++ ++W tr|C9JFG9|C9JFG9_HUMAN 43 TKVHELKEHNGqVTGIDWAPESNRIVTCGTDRNAYVW 79 689******555**************9999******* PP == domain 2 score: 4.3 bits; conditional E-value: 5.1 EEEEEETTSSEEEEEETTSE CS WD40 14 tslafspdgawlasGsdDgt 33 +++++ p+ + +a Gs + tr|C9JFG9|C9JFG9_HUMAN 100 RCVRWAPNENKFAVGSGSRV 119 69**********99975555 PP >> tr|C9JQM8|C9JQM8_HUMAN Actin-related protein 2/3 complex subunit 1B (Fragment) OS=Homo sapiens GN=ARPC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 0.2 6.6e-07 5.3e-05 2 37 .. 43 79 .. 42 80 .. 0.91 2 ? 4.3 0.0 5.1 4.1e+02 14 33 .. 100 119 .. 89 123 .. 0.83 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 6.6e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +++++l+ H++ vt++++ p+++ +++++ D++ ++W tr|C9JQM8|C9JQM8_HUMAN 43 TKVHELKEHNGqVTGIDWAPESNRIVTCGTDRNAYVW 79 689******555**************9999******* PP == domain 2 score: 4.3 bits; conditional E-value: 5.1 EEEEEETTSSEEEEEETTSE CS WD40 14 tslafspdgawlasGsdDgt 33 +++++ p+ + +a Gs + tr|C9JQM8|C9JQM8_HUMAN 100 RCVRWAPNENKFAVGSGSRV 119 69**********99975555 PP >> sp|Q5T5C0|STXB5_HUMAN Syntaxin-binding protein 5 OS=Homo sapiens GN=STXBP5 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 7.9 6.4e+02 9 38 .] 193 224 .. 187 224 .. 0.79 2 ! 15.7 0.3 0.0013 0.1 13 38 .] 240 265 .. 231 265 .. 0.88 3 ? 11.5 0.3 0.028 2.3 22 38 .] 438 464 .. 386 464 .. 0.61 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 7.9 SS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla..fspdgawlasGsdDgtvriWd 38 H ++v +++ ++g++l+ G + gtv +Wd sp|Q5T5C0|STXB5_HUMAN 193 SHpGPVVHISdnPMDEGKLLI-GFESGTVVLWD 224 576677788776677788887.**********9 PP == domain 2 score: 15.7 bits; conditional E-value: 0.0013 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++s+a++++g+ +++++ Dgt+ iW+ sp|Q5T5C0|STXB5_HUMAN 240 IHSVAWHHEGKQFICSHSDGTLTIWN 265 9*************9988*******8 PP == domain 3 score: 11.5 bits; conditional E-value: 0.028 SSE..........EEEEETTSEEEEEE CS WD40 22 gaw..........lasGsdDgtvriWd 38 g+w +++G+ Dg+v++Wd sp|Q5T5C0|STXB5_HUMAN 438 GNWglgaqsypeiIITGHADGSVKFWD 464 344666666677688***********9 PP >> tr|F8W1H8|F8W1H8_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1C PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.0 0.5 3.4e-07 2.7e-05 7 37 .. 76 108 .. 68 109 .. 0.86 2 ? 6.1 0.0 1.4 1.1e+02 3 26 .. 122 146 .. 120 151 .] 0.75 Alignments for each domain: == domain 1 score: 27.0 bits; conditional E-value: 3.4e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W tr|F8W1H8|F8W1H8_HUMAN 76 VCGHtGPVLDIDWCPHNDQViASGSEDCTVMVW 108 45**888************73699********* PP == domain 2 score: 6.1 bits; conditional E-value: 1.4 EEEEEESS.SSEEEEEEETTSSEEE CS WD40 3 clrtltGH.ssvtslafspdgawla 26 ++ +l+GH + v +a++p + ++ tr|F8W1H8|F8W1H8_HUMAN 122 PVVILEGHsKRVGIVAWHPTARNVL 146 77899***887*9999**9998853 PP >> tr|H3BPD7|H3BPD7_HUMAN Cirhin (Fragment) OS=Homo sapiens GN=CIRH1A PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.0 0.0052 0.42 11 38 .] 17 44 .. 1 44 [. 0.79 2 ! 16.1 0.0 0.00098 0.079 12 37 .. 103 128 .. 95 129 .. 0.89 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.0052 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 s+++++a++ ++ la + Dgtv i++ tr|H3BPD7|H3BPD7_HUMAN 17 SGIRCVAYNNQSNRLAVSRTDGTVEIYN 44 349************99967******97 PP == domain 2 score: 16.1 bits; conditional E-value: 0.00098 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +++s+a sp+g+ l+ G++Dg+v+++ tr|H3BPD7|H3BPD7_HUMAN 103 PIWSMAASPSGSQLLVGCEDGSVKLF 128 59**********************97 PP >> sp|Q562E7-4|WDR81_HUMAN Isoform 4 of WD repeat-containing protein 81 OS=Homo sapiens GN=WDR81 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.0 6e-07 4.8e-05 4 37 .. 1641 1675 .. 1639 1675 .. 0.92 2 ? 4.8 0.0 3.5 2.9e+02 6 38 .] 1692 1723 .. 1688 1723 .. 0.68 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 6e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l+++ GH + v ++a ++ ++++sGs+D+tvr+W sp|Q562E7-4|WDR81_HUMAN 1641 LQSFPGHsGAVKCVAPLSSEDFFLSGSKDRTVRLW 1675 6899***555************************* PP == domain 2 score: 4.8 bits; conditional E-value: 3.5 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 ++t H +sv + g++ ++ ++ Dg v++Wd sp|Q562E7-4|WDR81_HUMAN 1692 VYTQHrKSVFFV-----GQLeapqHVVSC-DGAVHVWD 1723 677888886555.....444444455578.*******9 PP >> sp|Q15751|HERC1_HUMAN Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens GN=HERC1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.1 0.0001 0.0083 6 38 .] 3423 3456 .. 3417 3456 .. 0.81 2 ? 8.5 0.1 0.25 20 8 37 .. 3623 3653 .. 3618 3653 .. 0.89 3 ? 3.7 1.2 7.8 6.3e+02 1 37 [. 3660 3703 .. 3660 3704 .. 0.82 4 ! 15.2 0.0 0.0018 0.14 2 37 .. 3738 3774 .. 3737 3781 .. 0.92 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 0.0001 EEESS.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssv.tslafspdgawlasGsdDgtvriWd 38 +l++H + v t++ ++ + +la+++ Dgt+r+W+ sp|Q15751|HERC1_HUMAN 3423 KLEAHqNRVmTCV-WCNKKGLLATSGNDGTIRVWN 3456 489**88898899.7777788898888*******8 PP == domain 2 score: 8.5 bits; conditional E-value: 0.25 ESSSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHss..vtslafspdgawlasGsdDgtvriW 37 ++H++ + s++++p g+ l+++ + +v++W sp|Q15751|HERC1_HUMAN 3623 DAHKDtlI-SMKWDPTGHILMTCAKEDSVKLW 3653 58966667.*********************** PP == domain 3 score: 3.7 bits; conditional E-value: 7.8 TEEEEEEESS.SSEEEEEEETTSSE.............EEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw.............lasGsdDgtvriW 37 + cl++l H s v+++ aw +a+G+ g v +W sp|Q15751|HERC1_HUMAN 3660 WCCLHSL-CHpSIVNGI------AWcrlpgkgsklqllMATGCQSGLVCVW 3703 579***9.8*7779***......777777777777876789********** PP == domain 4 score: 15.2 bits; conditional E-value: 0.0018 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +c++ l+GH ++v+ +afs+dg l+sG+ g iW sp|Q15751|HERC1_HUMAN 3738 KCVYQLRGHiTPVRTVAFSSDGLALVSGGLGGLMNIW 3774 79**************************988888888 PP >> tr|H0YJY3|H0YJY3_HUMAN Echinoderm microtubule-associated protein-like 1 (Fragment) OS=Homo sapiens GN=EML1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.4 9.2 7.5e+02 31 38 .] 27 34 .. 1 34 [. 0.54 2 ? 8.4 0.9 0.25 20 12 37 .. 50 91 .. 38 92 .. 0.68 3 ? 12.2 0.0 0.017 1.4 11 37 .. 112 137 .. 100 137 .. 0.83 4 ? 11.5 0.0 0.027 2.2 9 37 .. 151 180 .. 141 181 .. 0.86 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 9.2 TSEEEEEE CS WD40 31 DgtvriWd 38 ++vriWd tr|H0YJY3|H0YJY3_HUMAN 27 PPHVRIWD 34 57899998 PP == domain 2 score: 8.4 bits; conditional E-value: 0.25 S..EEEEE..............EETTSSE.EEEEETTSEEEEE CS WD40 12 s..vtsla..............fspdgaw.lasGsdDgtvriW 37 + vt++a f+p + +++++ + ++++W tr|H0YJY3|H0YJY3_HUMAN 50 DraVTCIAfskscsneavfaadFHPTDTNiIVTCG-KSHLYFW 91 34699999777666666666675555555457999.******9 PP == domain 3 score: 12.2 bits; conditional E-value: 0.017 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 ++v ++ fs +g+ + +G+ g++ +W tr|H0YJY3|H0YJY3_HUMAN 112 KFVLCVTFSENGDTI-TGDSSGNILVW 137 3499**********8.7*66******* PP == domain 4 score: 11.5 bits; conditional E-value: 0.027 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +++ +l+ +dg++++ G++D+++ W tr|H0YJY3|H0YJY3_HUMAN 151 AHeGGIFALCMLRDGTLVSGGGKDRKLISW 180 79888************97668****9988 PP >> tr|I3NI06|I3NI06_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.2 0.1 3.9e-09 3.1e-07 4 37 .. 70 105 .. 67 106 .. 0.88 Alignments for each domain: == domain 1 score: 33.2 bits; conditional E-value: 3.9e-09 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriW 37 + +l Hs+ vt+l+fsp ++l a+Gs D+tv++W tr|I3NI06|I3NI06_HUMAN 70 VAHLGCHSDlVTDLDFSPFDDFLlATGSADRTVKLW 105 679999*8889***********7369********** PP >> tr|G3V4I9|G3V4I9_HUMAN Protein NEDD1 (Fragment) OS=Homo sapiens GN=NEDD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.0 0.34 28 24 38 .] 2 16 .. 1 16 [. 0.93 2 ! 13.6 0.2 0.0057 0.46 5 32 .. 24 52 .. 20 58 .. 0.83 3 ? 10.0 0.3 0.081 6.6 8 38 .] 68 102 .. 56 102 .. 0.77 4 ? 4.8 0.0 3.5 2.9e+02 9 38 .] 115 146 .. 106 146 .. 0.71 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.34 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +l+sG+ ++tv iWd tr|G3V4I9|G3V4I9_HUMAN 2 YLVSGGLNNTVNIWD 16 689***********9 PP == domain 2 score: 13.6 bits; conditional E-value: 0.0057 EEEESSSS.EEEEEEETTSSEEEEEETTS CS WD40 5 rtltGHss.vtslafspdgawlasGsdDg 32 r+l+ H++ vt++ ++ + ++asGs g tr|G3V4I9|G3V4I9_HUMAN 24 RSLKDHKDqVTCVTYNWNDCYIASGSLSG 52 78999*555****************9655 PP == domain 3 score: 10.0 bits; conditional E-value: 0.081 ESS.SS..EEEEEEETTSSEEEEE..ETTSEEEEEE CS WD40 8 tGH.ss..vtslafspdgawlasG..sdDgtvriWd 38 GH s+ v++l++s ++ l+ G sd+g v +Wd tr|G3V4I9|G3V4I9_HUMAN 68 FGHgSNqsVRHLKYSLFKKSLL-GsvSDNGIVTLWD 102 39973367****9998999999.53579*******9 PP == domain 4 score: 4.8 bits; conditional E-value: 3.5 SS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasG.sdDgtvriWd 38 H + ++++fsp + +l+ + D+ + ++d tr|G3V4I9|G3V4I9_HUMAN 115 VHkAPASGICFSPVNELLFVTiGLDKRIILYD 146 56444679999**9999864334499999987 PP >> sp|Q9UI46|DNAI1_HUMAN Dynein intermediate chain 1, axonemal OS=Homo sapiens GN=DNAI1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 0.019 1.5 7 38 .] 380 412 .. 375 412 .. 0.84 2 ! 18.6 1.7 0.00015 0.012 2 38 .] 531 569 .. 530 569 .. 0.87 3 ? 5.0 0.0 3.2 2.6e+02 12 38 .] 584 611 .. 574 611 .. 0.82 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.019 EESSSSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 7 ltGHssvtslafspdgawla.sGsdDgtvriWd 38 ++ s+v +l+ + d+++l+ G++Dg+v i++ sp|Q9UI46|DNAI1_HUMAN 380 FSSNSGVMCLDIHVDHPYLVaVGHYDGNVAIYN 412 556677************863799*****9997 PP == domain 2 score: 18.6 bits; conditional E-value: 0.00015 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 q l t+++H sv ++++p+++ ++ s+s D tv+iWd sp|Q9UI46|DNAI1_HUMAN 531 QFLDTYDAHnMSVDTVSWNPYHTKVFmSCSSDWTVKIWD 569 56789****777************8558877*******9 PP == domain 3 score: 5.0 bits; conditional E-value: 3.2 SEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 12 svtslafspdgawlasG.sdDgtvriWd 38 v ++a+ p+++ ++++ + Dg+ +i+d sp|Q9UI46|DNAI1_HUMAN 584 AVGDVAWAPYSSTVFAAvTTDGKAHIFD 611 4889*********9877656****9998 PP >> tr|I3L1G9|I3L1G9_HUMAN Coronin OS=Homo sapiens GN=CORO7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.0 0.1 4.4e-09 3.6e-07 4 37 .. 70 105 .. 67 106 .. 0.88 Alignments for each domain: == domain 1 score: 33.0 bits; conditional E-value: 4.4e-09 EEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEE CS WD40 4 lrtltGHss.vtslafspdgawl.asGsdDgtvriW 37 + +l Hs+ vt+l+fsp ++l a+Gs D+tv++W tr|I3L1G9|I3L1G9_HUMAN 70 VAHLGCHSDlVTDLDFSPFDDFLlATGSADRTVKLW 105 679999*8889***********7369********** PP >> sp|Q12770-3|SCAP_HUMAN Isoform 3 of Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sa # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.066 5.4 5 37 .. 564 596 .. 560 597 .. 0.72 2 ! 19.5 0.2 8e-05 0.0065 2 38 .] 602 638 .. 601 638 .. 0.79 3 ? 7.1 2.0 0.65 52 5 38 .] 647 678 .. 642 678 .. 0.69 4 ? 3.8 0.2 7.3 5.9e+02 23 38 .] 704 718 .. 698 718 .. 0.89 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.066 EEEE.SS.SSEEEEEEETTSSE....EEEEETTSEEEEE CS WD40 5 rtlt.GH.ssvtslafspdgaw....lasGsdDgtvriW 37 +t +H +++t+l + l++Gs D+t+r++ sp|Q12770-3|SCAP_HUMAN 564 HTVPcAHqKPITAL------KAaagrLVTGSQDHTLRVF 596 4543489999**99......333444679********97 PP == domain 2 score: 19.5 bits; conditional E-value: 8e-05 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 cl tl GH + +t + d+++ lasG+ Dg + +Wd sp|Q12770-3|SCAP_HUMAN 602 CCLFTLQGHsGAITTV--YIDQTMvLASGGQDGAICLWD 638 599******5559999..3344444689**********9 PP == domain 3 score: 7.1 bits; conditional E-value: 0.65 EEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +++ +H ++vtsl + ++s++ D + iWd sp|Q12770-3|SCAP_HUMAN 647 HVF-AHrGDVTSL------TCttscVISSGLDDLISIWD 678 445.899999999......333343556666*******9 PP == domain 4 score: 3.8 bits; conditional E-value: 7.3 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++l++G+ g v +Wd sp|Q12770-3|SCAP_HUMAN 704 NLLVTGG-QGCVSFWD 718 6799***.*******9 PP >> tr|F8VUX3|F8VUX3_HUMAN Coronin OS=Homo sapiens GN=CORO1C PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.5 3.7e-07 3e-05 7 37 .. 76 108 .. 68 109 .. 0.86 2 ? 5.1 0.0 2.9 2.3e+02 3 24 .. 122 144 .. 120 156 .. 0.81 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 3.7e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W tr|F8VUX3|F8VUX3_HUMAN 76 VCGHtGPVLDIDWCPHNDQViASGSEDCTVMVW 108 45**888************73699********* PP == domain 2 score: 5.1 bits; conditional E-value: 2.9 EEEEEESS.SSEEEEEEETTSSE CS WD40 3 clrtltGH.ssvtslafspdgaw 24 ++ +l+GH + v +a++p + tr|F8VUX3|F8VUX3_HUMAN 122 PVVILEGHsKRVGIVAWHPTARN 144 77899***877*99999998876 PP >> tr|B4DLQ7|B4DLQ7_HUMAN Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens GN=ARPC1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 0.5 0.0059 0.48 13 38 .] 6 33 .. 2 33 .. 0.80 2 ! 16.2 0.2 0.00086 0.07 12 37 .. 93 122 .. 85 123 .. 0.81 3 ? 8.9 0.9 0.18 15 2 36 .. 146 183 .. 145 185 .. 0.80 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 0.0059 EEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 13 vtsla..fspdgawlasGsdDgtvriWd 38 +++++ + p ++ +++++ D++ ++W+ tr|B4DLQ7|B4DLQ7_HUMAN 6 IHCFCidWAPKSDRIVTCGADRNAYVWS 33 5544444**********999*******5 PP == domain 2 score: 16.2 bits; conditional E-value: 0.00086 S....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s....vtslafspdgawlasGsdDgtvriW 37 + v sl+++p++ +la+Gs D ++r++ tr|B4DLQ7|B4DLQ7_HUMAN 93 PirstVLSLDWHPNNVLLAAGSCDFKCRVF 122 3444489**************99*****97 PP == domain 3 score: 8.9 bits; conditional E-value: 0.18 EEEEEEESS.SS..EEEEEEETTSSEEE.EEETTSEEEE CS WD40 2 qclrtltGH.ss..vtslafspdgawla.sGsdDgtvri 36 q++ ++ G ++ v++++fs +g+ la ++ D tv + tr|B4DLQ7|B4DLQ7_HUMAN 146 QLMSEFGGSgTGgwVHGVSFSASGSRLAwVSH-DSTVSV 183 67788877753346*************98889.**9976 PP >> tr|Q3B794|Q3B794_HUMAN STXBP5 protein OS=Homo sapiens GN=STXBP5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 5 4e+02 22 38 .] 111 126 .. 87 126 .. 0.66 2 ? 5.9 0.0 1.5 1.3e+02 9 38 .] 193 224 .. 187 224 .. 0.80 3 ! 17.9 0.3 0.00025 0.02 13 38 .] 240 265 .. 231 265 .. 0.88 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 5 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 ga l+s+ D t+++W+ tr|Q3B794|Q3B794_HUMAN 111 GA-LVSALADDTLHLWN 126 33.568866*******8 PP == domain 2 score: 5.9 bits; conditional E-value: 1.5 SS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla..fspdgawlasGsdDgtvriWd 38 H ++v +++ ++g++l+ G + gtv +Wd tr|Q3B794|Q3B794_HUMAN 193 SHpGPVVHISdnPMDEGKLLI-GFESGTVVLWD 224 576777788777777888887.**********9 PP == domain 3 score: 17.9 bits; conditional E-value: 0.00025 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++s+a++++g+ +++++ Dgt+ iW+ tr|Q3B794|Q3B794_HUMAN 240 IHSVAWHHEGKQFICSHSDGTLTIWN 265 9*************9988*******8 PP >> tr|E5RFG6|E5RFG6_HUMAN TBC1 domain family member 31 (Fragment) OS=Homo sapiens GN=TBC1D31 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.0 0.71 58 15 38 .] 37 60 .. 21 60 .. 0.86 2 ! 12.9 0.2 0.0095 0.77 7 38 .] 112 143 .. 105 143 .. 0.87 3 ? 7.9 0.0 0.37 30 18 37 .. 212 231 .. 200 232 .. 0.88 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.71 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +af+ g+ l++G+ g+++++d tr|E5RFG6|E5RFG6_HUMAN 37 NVAFDGTGDCLIAGDHQGNIYVFD 60 588***********88*****998 PP == domain 2 score: 12.9 bits; conditional E-value: 0.0095 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH ssv s++++ +g++ ++ s t +Wd tr|E5RFG6|E5RFG6_HUMAN 112 MRGHeSSVFSISVHASGKYAITTS-SDTAQLWD 143 48**999************99989.88888887 PP == domain 3 score: 7.9 bits; conditional E-value: 0.37 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 + +dg+ la+G++ +++++W tr|E5RFG6|E5RFG6_HUMAN 212 VTRDGRILAAGGKSNHLHLW 231 5899**************** PP >> sp|Q5T5C0-3|STXB5_HUMAN Isoform 3 of Syntaxin-binding protein 5 OS=Homo sapiens GN=STXBP5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7.5 6e+02 9 38 .] 193 224 .. 187 224 .. 0.79 2 ! 15.8 0.3 0.0012 0.097 13 38 .] 240 265 .. 231 265 .. 0.88 3 ? 11.5 0.3 0.026 2.1 22 38 .] 438 464 .. 386 464 .. 0.61 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.5 SS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla..fspdgawlasGsdDgtvriWd 38 H ++v +++ ++g++l+ G + gtv +Wd sp|Q5T5C0-3|STXB5_HUMAN 193 SHpGPVVHISdnPMDEGKLLI-GFESGTVVLWD 224 576677788776677788887.**********9 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0012 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++s+a++++g+ +++++ Dgt+ iW+ sp|Q5T5C0-3|STXB5_HUMAN 240 IHSVAWHHEGKQFICSHSDGTLTIWN 265 9*************9988*******8 PP == domain 3 score: 11.5 bits; conditional E-value: 0.026 SSE..........EEEEETTSEEEEEE CS WD40 22 gaw..........lasGsdDgtvriWd 38 g+w +++G+ Dg+v++Wd sp|Q5T5C0-3|STXB5_HUMAN 438 GNWglgaqsypeiIITGHADGSVKFWD 464 344666666677688***********9 PP >> sp|Q5T5C0-2|STXB5_HUMAN Isoform 2 of Syntaxin-binding protein 5 OS=Homo sapiens GN=STXBP5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 7.6 6.2e+02 9 38 .] 193 224 .. 187 224 .. 0.79 2 ! 15.8 0.3 0.0012 0.098 13 38 .] 240 265 .. 231 265 .. 0.88 3 ? 11.5 0.3 0.027 2.2 22 38 .] 438 464 .. 386 464 .. 0.61 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 7.6 SS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla..fspdgawlasGsdDgtvriWd 38 H ++v +++ ++g++l+ G + gtv +Wd sp|Q5T5C0-2|STXB5_HUMAN 193 SHpGPVVHISdnPMDEGKLLI-GFESGTVVLWD 224 576677788776677788887.**********9 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0012 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 ++s+a++++g+ +++++ Dgt+ iW+ sp|Q5T5C0-2|STXB5_HUMAN 240 IHSVAWHHEGKQFICSHSDGTLTIWN 265 9*************9988*******8 PP == domain 3 score: 11.5 bits; conditional E-value: 0.027 SSE..........EEEEETTSEEEEEE CS WD40 22 gaw..........lasGsdDgtvriWd 38 g+w +++G+ Dg+v++Wd sp|Q5T5C0-2|STXB5_HUMAN 438 GNWglgaqsypeiIITGHADGSVKFWD 464 344666666677688***********9 PP >> tr|E7ERC8|E7ERC8_HUMAN Protein SEC13 homolog (Fragment) OS=Homo sapiens GN=SEC13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.1 0.00078 0.063 8 38 .] 13 44 .. 6 44 .. 0.85 2 ! 15.8 0.0 0.0011 0.093 5 34 .. 54 86 .] 50 86 .] 0.82 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 0.00078 ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriWd 38 t H + +++ + + +g+ la++s D++v+i+d tr|E7ERC8|E7ERC8_HUMAN 13 TSHEDmIHDAQMDYYGTRLATCSSDRSVKIFD 44 46755699999999********88******98 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0011 EEEESS.SSEEEEE..EETTSSEEEEEETTSEE CS WD40 5 rtltGH.ssvtsla..fspdgawlasGsdDgtv 34 l+GH ++v+ +a + +g+ las+s+D++v tr|E7ERC8|E7ERC8_HUMAN 54 ADLRGHeGPVWQVAwaHPMYGNILASCSYDRKV 86 5699**999****7667777777*******987 PP >> tr|H7C0S9|H7C0S9_HUMAN WD repeat domain-containing protein 83 (Fragment) OS=Homo sapiens GN=WDR83 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.1 5.8 4.7e+02 31 38 .] 1 8 [. 1 8 [. 0.96 2 ! 26.6 0.2 4.6e-07 3.7e-05 1 38 [] 12 50 .. 12 50 .. 0.91 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 5.8 TSEEEEEE CS WD40 31 DgtvriWd 38 D+t+++W+ tr|H7C0S9|H7C0S9_HUMAN 1 DKTLKLWN 8 9******8 PP == domain 2 score: 26.6 bits; conditional E-value: 4.6e-07 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 g++lrt++GH+ v + a s d++ l+sG+ D+ v +Wd tr|H7C0S9|H7C0S9_HUMAN 12 GTLLRTYSGHGYeVLDAAGSFDNSSLCSGGGDKAVVLWD 50 5789******446****************88*******9 PP >> sp|P50851-2|LRBA_HUMAN Isoform 2 of Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens GN=L # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 3.2 2.6e+02 13 37 .. 2585 2612 .. 2571 2613 .. 0.73 2 ? 10.4 0.2 0.06 4.9 4 37 .. 2620 2658 .. 2617 2659 .. 0.82 3 ? 7.3 0.0 0.59 48 10 34 .. 2767 2790 .. 2758 2793 .. 0.77 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 3.2 EEEEE..EETTSSE.EEEEETTSEEEEE CS WD40 13 vtsla..fspdgaw.lasGsdDgtvriW 37 v+s++ +d+++ l++G +D++ r++ sp|P50851-2|LRBA_HUMAN 2585 VHSQCfvITSDNRYiLVCGFWDKSFRVY 2612 55555666666677256889******98 PP == domain 2 score: 10.4 bits; conditional E-value: 0.06 EEEEESSSS.EEEEE....EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtsla....fspdgawlasGsdDgtvriW 37 +++ GH + vt+la + + +++sGs+D t+ +W sp|P50851-2|LRBA_HUMAN 2620 IQVVFGHWDvVTCLArsesYIGGNCYILSGSRDATLLLW 2658 566669*3358***99999888888899*********** PP == domain 3 score: 7.3 bits; conditional E-value: 0.59 SSSEEEEEEETTSSEEEEEETTSEE CS WD40 10 HssvtslafspdgawlasGsdDgtv 34 +++++++ s+dg++l++G+ D+ v sp|P50851-2|LRBA_HUMAN 2767 DDNIRAIQLSRDGQYLLTGG-DRGV 2790 44599***************.9866 PP >> tr|F5H1X8|F5H1X8_HUMAN Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens GN=LRBA PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 3.2 2.6e+02 13 37 .. 2585 2612 .. 2571 2613 .. 0.73 2 ? 10.4 0.2 0.06 4.9 4 37 .. 2620 2658 .. 2617 2659 .. 0.82 3 ? 7.3 0.0 0.59 48 10 34 .. 2768 2791 .. 2759 2794 .. 0.77 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 3.2 EEEEE..EETTSSE.EEEEETTSEEEEE CS WD40 13 vtsla..fspdgaw.lasGsdDgtvriW 37 v+s++ +d+++ l++G +D++ r++ tr|F5H1X8|F5H1X8_HUMAN 2585 VHSQCfvITSDNRYiLVCGFWDKSFRVY 2612 55555666666677256889******98 PP == domain 2 score: 10.4 bits; conditional E-value: 0.06 EEEEESSSS.EEEEE....EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtsla....fspdgawlasGsdDgtvriW 37 +++ GH + vt+la + + +++sGs+D t+ +W tr|F5H1X8|F5H1X8_HUMAN 2620 IQVVFGHWDvVTCLArsesYIGGNCYILSGSRDATLLLW 2658 566669*3358***99999888888899*********** PP == domain 3 score: 7.3 bits; conditional E-value: 0.59 SSSEEEEEEETTSSEEEEEETTSEE CS WD40 10 HssvtslafspdgawlasGsdDgtv 34 +++++++ s+dg++l++G+ D+ v tr|F5H1X8|F5H1X8_HUMAN 2768 DDNIRAIQLSRDGQYLLTGG-DRGV 2791 44599***************.9866 PP >> sp|Q66LE6|2ABD_HUMAN Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapie # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 1.1 91 13 37 .. 37 61 .. 17 62 .. 0.77 2 ? 7.1 0.0 0.66 54 24 38 .] 113 129 .. 80 129 .. 0.71 3 ? 4.5 0.1 4.3 3.5e+02 9 37 .. 181 209 .. 173 210 .. 0.69 4 ? 3.8 0.0 7.3 5.9e+02 13 36 .. 235 259 .. 225 261 .. 0.75 5 ? 8.0 0.1 0.34 28 11 38 .] 292 318 .. 283 318 .. 0.89 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 1.1 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++ + f+ +g++la+G++ g v i+ sp|Q66LE6|2ABD_HUMAN 37 ISTVEFNYSGDLLATGDKGGRVVIF 61 68888***********988888875 PP == domain 2 score: 7.1 bits; conditional E-value: 0.66 E...EEEEETTSEEEEEE CS WD40 24 w...lasGsdDgtvriWd 38 l+s D+t+++W+ sp|Q66LE6|2ABD_HUMAN 113 AahfLLSTN-DKTIKLWK 129 244488766.*******6 PP == domain 3 score: 4.5 bits; conditional E-value: 4.3 SS.SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla.fspdgawlasGsdDgtvriW 37 +H +++s++ +s++ ++l s++ D + +W sp|Q66LE6|2ABD_HUMAN 181 AHtYHINSISvNSDHETYL-SAD-DLRINLW 209 67445****9555555555.677.*999999 PP == domain 4 score: 3.8 bits; conditional E-value: 7.3 EEEEEEETTSSE..EEEEETTSEEEE CS WD40 13 vtslafspdgaw..lasGsdDgtvri 36 +t+ f+p++ + s+s +gt+r+ sp|Q66LE6|2ABD_HUMAN 235 ITAAEFHPHQCNvfVYSSS-KGTIRL 259 5667777777772246999.*****8 PP == domain 5 score: 8.0 bits; conditional E-value: 0.34 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d +v++Wd sp|Q66LE6|2ABD_HUMAN 292 SSISDVKFSHSGRYMMT-RDYLSVKVWD 318 46999***********6.88*******9 PP >> sp|P50851|LRBA_HUMAN Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens GN=LRBA PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 3.2 2.6e+02 13 37 .. 2596 2623 .. 2582 2624 .. 0.73 2 ? 10.4 0.2 0.06 4.9 4 37 .. 2631 2669 .. 2628 2670 .. 0.82 3 ? 7.3 0.0 0.59 48 10 34 .. 2779 2802 .. 2770 2805 .. 0.77 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 3.2 EEEEE..EETTSSE.EEEEETTSEEEEE CS WD40 13 vtsla..fspdgaw.lasGsdDgtvriW 37 v+s++ +d+++ l++G +D++ r++ sp|P50851|LRBA_HUMAN 2596 VHSQCfvITSDNRYiLVCGFWDKSFRVY 2623 55555666666677256889******98 PP == domain 2 score: 10.4 bits; conditional E-value: 0.06 EEEEESSSS.EEEEE....EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtsla....fspdgawlasGsdDgtvriW 37 +++ GH + vt+la + + +++sGs+D t+ +W sp|P50851|LRBA_HUMAN 2631 IQVVFGHWDvVTCLArsesYIGGNCYILSGSRDATLLLW 2669 566669*3358***99999888888899*********** PP == domain 3 score: 7.3 bits; conditional E-value: 0.59 SSSEEEEEEETTSSEEEEEETTSEE CS WD40 10 HssvtslafspdgawlasGsdDgtv 34 +++++++ s+dg++l++G+ D+ v sp|P50851|LRBA_HUMAN 2779 DDNIRAIQLSRDGQYLLTGG-DRGV 2802 44599***************.9866 PP >> tr|G3V3S1|G3V3S1_HUMAN DDB1- and CUL4-associated factor 5 (Fragment) OS=Homo sapiens GN=DCAF5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.044 3.6 9 35 .. 18 44 .. 10 47 .. 0.81 2 ! 20.3 0.1 4.3e-05 0.0035 7 38 .] 56 88 .. 50 88 .. 0.81 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.044 SSSSEEEEEEETTSSEEEEEETTSEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvr 35 Hs++ +laf++ ++ ++sG+ D v tr|G3V3S1|G3V3S1_HUMAN 18 HHSNIFCLAFNSGNTKVFSGGNDEQVI 44 4588****************9887765 PP == domain 2 score: 20.3 bits; conditional E-value: 4.3e-05 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 + +H + v++l++sp ++ + as+sdDg v iWd tr|G3V3S1|G3V3S1_HUMAN 56 F-AHeDAVYGLSVSPVNDNIfASSSDDGRVLIWD 88 4.79777*****9999999735779********9 PP >> tr|Q5SVS2|Q5SVS2_HUMAN F-box/WD repeat-containing protein 4 (Fragment) OS=Homo sapiens GN=FBXW4 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.2 0.036 2.9 2 34 .. 110 141 .. 109 145 .. 0.83 2 ! 19.3 0.1 9.4e-05 0.0076 6 37 .. 153 183 .. 148 183 .. 0.86 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.036 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtv 34 ++l+++ GH +v+++ + +++ +++G+ Dg++ tr|Q5SVS2|Q5SVS2_HUMAN 110 RPLGVFAGHdEDVCHF-VLANSHIVSAGG-DGKI 141 6899*****888*777.888888899999.**98 PP == domain 2 score: 19.3 bits; conditional E-value: 9.4e-05 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++H + v+++ + g ++sGs+D+t ++W tr|Q5SVS2|Q5SVS2_HUMAN 153 KYSAHeQEVNCV--DCKGGIIVSGSRDRTAKVW 183 589**888****..66667799*********** PP >> sp|Q9UG01-2|IF172_HUMAN Isoform 2 of Intraflagellar transport protein 172 homolog OS=Homo sapiens GN=IFT172 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.013 1.1 12 38 .] 15 44 .. 3 44 .. 0.77 2 ? 5.8 0.0 1.7 1.4e+02 13 37 .. 69 93 .. 60 94 .. 0.86 3 ? 3.4 0.2 9.6 7.8e+02 7 34 .. 148 176 .. 142 177 .. 0.79 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 S...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvriWd 38 + vt++a+s+++a +a ++ D+ v ++d sp|Q9UG01-2|IF172_HUMAN 15 GaakVTCMAWSQNNAKFAVCTVDRVVLLYD 44 1345***********************998 PP == domain 2 score: 5.8 bits; conditional E-value: 1.7 EEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 13 vtslafspdgawlasG.sdDgtvriW 37 v ++afspd++ +a G + D+ ++++ sp|Q9UG01-2|IF172_HUMAN 69 VKGMAFSPDSTKIAIGqT-DNIIYVY 93 7899************66.****998 PP == domain 3 score: 3.4 bits; conditional E-value: 9.6 EESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtv 34 + G s v sl ++ +g+ ++sG+ Dgt+ sp|Q9UG01-2|IF172_HUMAN 148 IYGTeSYVVSLTTNCSGKGILSGHADGTI 176 446656688999999999999*******9 PP >> sp|Q96KV7-3|WDR90_HUMAN Isoform 3 of WD repeat-containing protein 90 OS=Homo sapiens GN=WDR90 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 2.4 2e+02 4 28 .. 402 427 .. 400 439 .. 0.75 2 ? 8.3 0.3 0.27 22 12 33 .. 454 476 .. 443 478 .. 0.76 3 ? 8.5 0.0 0.23 19 9 37 .. 501 531 .. 494 532 .. 0.70 4 ? 6.1 0.0 1.3 1.1e+02 13 37 .. 622 644 .. 607 644 .. 0.75 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 2.4 EEEEESS.SSEEEEEEETTSSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG 28 +r + GH + v++la + ++++las+ sp|Q96KV7-3|WDR90_HUMAN 402 QRFFLGHtDKVSALALDGSSSLLASA 427 57788**555*************986 PP == domain 2 score: 8.3 bits; conditional E-value: 0.27 S.EEEEEEETTSSEEEEE.ETTSE CS WD40 12 s.vtslafspdgawlasG.sdDgt 33 + v+sl+fs++ga+l +G ++D++ sp|Q96KV7-3|WDR90_HUMAN 454 HvVCSLSFSDSGALL-CGvGKDHH 476 237***********9.58899997 PP == domain 3 score: 8.5 bits; conditional E-value: 0.23 SS..SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 9 GH..ssvtsla.fspdgawlasGsdDgtvriW 37 +H ++v +++ + d + +as++ g+vr+W sp|Q96KV7-3|WDR90_HUMAN 501 AHtdFDVQAFRvTFFDETRMASCG-QGSVRLW 531 6753347666664445566699**.******* PP == domain 4 score: 6.1 bits; conditional E-value: 1.3 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++sl s + a+ a Gs+Dg +r+W sp|Q96KV7-3|WDR90_HUMAN 622 ISSL--SVSPAMCAVGSEDGFLRLW 644 5666..666677788********** PP >> sp|Q96KV7-5|WDR90_HUMAN Isoform 5 of WD repeat-containing protein 90 OS=Homo sapiens GN=WDR90 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 2.4 2e+02 4 28 .. 403 428 .. 401 440 .. 0.75 2 ? 8.3 0.3 0.27 22 12 33 .. 455 477 .. 444 479 .. 0.76 3 ? 8.5 0.0 0.23 19 9 37 .. 502 532 .. 495 533 .. 0.70 4 ? 6.1 0.0 1.3 1.1e+02 13 37 .. 623 645 .. 608 645 .. 0.75 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 2.4 EEEEESS.SSEEEEEEETTSSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG 28 +r + GH + v++la + ++++las+ sp|Q96KV7-5|WDR90_HUMAN 403 QRFFLGHtDKVSALALDGSSSLLASA 428 57788**555*************986 PP == domain 2 score: 8.3 bits; conditional E-value: 0.27 S.EEEEEEETTSSEEEEE.ETTSE CS WD40 12 s.vtslafspdgawlasG.sdDgt 33 + v+sl+fs++ga+l +G ++D++ sp|Q96KV7-5|WDR90_HUMAN 455 HvVCSLSFSDSGALL-CGvGKDHH 477 237***********9.58899997 PP == domain 3 score: 8.5 bits; conditional E-value: 0.23 SS..SSEEEEE.EETTSSEEEEEETTSEEEEE CS WD40 9 GH..ssvtsla.fspdgawlasGsdDgtvriW 37 +H ++v +++ + d + +as++ g+vr+W sp|Q96KV7-5|WDR90_HUMAN 502 AHtdFDVQAFRvTFFDETRMASCG-QGSVRLW 532 6753347666664445566699**.******* PP == domain 4 score: 6.1 bits; conditional E-value: 1.3 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++sl s + a+ a Gs+Dg +r+W sp|Q96KV7-5|WDR90_HUMAN 623 ISSL--SVSPAMCAVGSEDGFLRLW 645 5666..666677788********** PP >> tr|Q8ND98|Q8ND98_HUMAN Putative uncharacterized protein DKFZp434B156 OS=Homo sapiens GN=DKFZp434B156 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.0 9.6e-06 0.00078 3 38 .] 2 44 .. 1 44 [. 0.74 2 ? 4.1 0.0 5.7 4.6e+02 21 38 .] 78 95 .. 62 95 .. 0.78 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 9.6e-06 EEEEEESSSS.EEEEE......EETTSSE.....EEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtsla......fspdgaw.....lasGsdDgtvriWd 38 ++++ +GH+ +++++ +++Gs+Dgtv++Wd tr|Q8ND98|Q8ND98_HUMAN 2 PVYSVKGHKEiINAIDgigglgI-----GegapeIVTGSRDGTVKVWD 44 578899**7757*9955555543.....05555599***********9 PP == domain 2 score: 4.1 bits; conditional E-value: 5.7 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 + + +++G d+g ++++d tr|Q8ND98|Q8ND98_HUMAN 78 EERVVCAGYDNGDIKLFD 95 4455889999******98 PP >> tr|D6RHJ5|D6RHJ5_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 0.072 5.9 4 31 .. 8 37 .. 5 38 .. 0.77 2 ! 21.5 0.0 1.8e-05 0.0015 13 37 .. 55 79 .. 40 80 .. 0.88 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.072 EEEEESS.SSEEEEE.EETTSSEEEEEETT CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdD 31 +tl+GH ++vt +a +++ ++++s+s+D tr|D6RHJ5|D6RHJ5_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRD 37 5799***666****9866667777788776 PP == domain 2 score: 21.5 bits; conditional E-value: 1.8e-05 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 tsla+s dg+ l++G D+ vr+W tr|D6RHJ5|D6RHJ5_HUMAN 55 CTSLAWSADGQTLFAGYTDNLVRVW 79 59**************88******* PP >> sp|Q6RI45-3|BRWD3_HUMAN Isoform 3 of Bromodomain and WD repeat-containing protein 3 OS=Homo sapiens GN=BRWD3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.1 5.6e-05 0.0045 1 38 [] 51 90 .. 51 90 .. 0.71 2 ? 11.7 0.2 0.023 1.9 7 32 .. 106 129 .. 99 136 .. 0.80 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 5.6e-05 TEEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 gq+l+tl+GH + v l + d++ ++s++ Dg++ iWd sp|Q6RI45-3|BRWD3_HUMAN 51 GQLLHTLSGHdDEVFVLEaHPFDQRIILSAGHDGNIFIWD 90 799*******5557666633555555556555*******9 PP == domain 2 score: 11.7 bits; conditional E-value: 0.023 EESSSSEEEEEEETTSSEEEEEETTS CS WD40 7 ltGHssvtslafspdgawlasGsdDg 32 GH+ v +++fspdg+ +a ++ D sp|Q6RI45-3|BRWD3_HUMAN 106 GQGHGAVFDCKFSPDGNHFA-CT-DS 129 569988************97.66.54 PP >> sp|Q9Y2T4|2ABG_HUMAN Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform OS=Homo sapie # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.51 41 7 37 .. 15 51 .. 8 52 .. 0.72 2 ? 6.9 0.0 0.77 62 13 38 .] 92 119 .. 70 119 .. 0.68 3 ? 4.4 0.1 4.7 3.8e+02 8 37 .. 170 199 .. 163 200 .. 0.70 4 ? 9.6 0.1 0.1 8.5 11 38 .] 282 308 .. 273 308 .. 0.89 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.51 EESSSS......EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss......vtslafspdgawlasGsdDgtvriW 37 l+ Hs ++ + f++ g +la+G++ g v i+ sp|Q9Y2T4|2ABG_HUMAN 15 LRDHSYvteadiISTVEFNHTGELLATGDKGGRVVIF 51 46774533445457788***********988888875 PP == domain 2 score: 6.9 bits; conditional E-value: 0.77 EEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw...lasGsdDgtvriWd 38 ++ +++ p ++ l+s D+t+++W+ sp|Q9Y2T4|2ABG_HUMAN 92 INKIKWLPQQNAahsLLSTN-DKTIKLWK 119 66675444444466667656.*******6 PP == domain 3 score: 4.4 bits; conditional E-value: 4.7 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 GH +++s+++++d +s++ D + +W sp|Q9Y2T4|2ABG_HUMAN 170 NGHtYHINSISVNSDCETYMSAD-DLRINLW 199 499666****9555555545677.9999999 PP == domain 4 score: 9.6 bits; conditional E-value: 0.1 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ssv++++fs++g+++++ d tv++Wd sp|Q9Y2T4|2ABG_HUMAN 282 SSVSDVKFSHSGRYMLT-RDYLTVKVWD 308 4699999*********6.89*******9 PP >> sp|Q9Y2T4-2|2ABG_HUMAN Isoform 2 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isofor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 2.8 2.3e+02 13 37 .. 27 51 .. 12 52 .. 0.83 2 ? 6.9 0.0 0.77 62 13 38 .] 92 119 .. 70 119 .. 0.68 3 ? 4.4 0.1 4.7 3.8e+02 8 37 .. 170 199 .. 163 200 .. 0.70 4 ? 9.6 0.1 0.1 8.5 11 38 .] 282 308 .. 273 308 .. 0.89 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 2.8 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++ + f++ g +la+G++ g v i+ sp|Q9Y2T4-2|2ABG_HUMAN 27 ISTVEFNHTGELLATGDKGGRVVIF 51 68999***********988888875 PP == domain 2 score: 6.9 bits; conditional E-value: 0.77 EEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw...lasGsdDgtvriWd 38 ++ +++ p ++ l+s D+t+++W+ sp|Q9Y2T4-2|2ABG_HUMAN 92 INKIKWLPQQNAahsLLSTN-DKTIKLWK 119 66675444444466667656.*******6 PP == domain 3 score: 4.4 bits; conditional E-value: 4.7 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 GH +++s+++++d +s++ D + +W sp|Q9Y2T4-2|2ABG_HUMAN 170 NGHtYHINSISVNSDCETYMSAD-DLRINLW 199 499666****9555555545677.9999999 PP == domain 4 score: 9.6 bits; conditional E-value: 0.1 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ssv++++fs++g+++++ d tv++Wd sp|Q9Y2T4-2|2ABG_HUMAN 282 SSVSDVKFSHSGRYMLT-RDYLTVKVWD 308 4699999*********6.89*******9 PP >> tr|G3V221|G3V221_HUMAN Mitogen-activated protein kinase organizer 1, isoform CRA_c OS=Homo sapiens GN=WDR83 PE=4 SV= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.9 0.0 1.8e-07 1.4e-05 4 38 .] 18 53 .. 15 53 .. 0.81 2 ? 3.6 0.0 8.7 7.1e+02 1 10 [. 57 66 .. 57 69 .. 0.85 Alignments for each domain: == domain 1 score: 27.9 bits; conditional E-value: 1.8e-07 EEEEE.SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GHssvtslafspdgawlasGsdDgtvriWd 38 l+tl+ G++ v++++f+ dg++ ++++ D+t+++W+ tr|G3V221|G3V221_HUMAN 18 LKTLDcGQGAVRAVRFNVDGNYCLTCGSDKTLKLWN 53 6677657767************776655*******8 PP == domain 2 score: 3.6 bits; conditional E-value: 8.7 TEEEEEEESS CS WD40 1 gqclrtltGH 10 g++lrt++GH tr|G3V221|G3V221_HUMAN 57 GTLLRTYSGH 66 5789****** PP >> sp|Q9Y2T4-4|2ABG_HUMAN Isoform 4 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isofor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 3.7 3e+02 13 37 .. 20 44 .. 12 45 .. 0.85 2 ? 6.9 0.0 0.75 61 13 38 .] 85 112 .. 63 112 .. 0.68 3 ? 4.4 0.1 4.6 3.7e+02 8 37 .. 163 192 .. 156 193 .. 0.70 4 ? 9.7 0.1 0.1 8.3 11 38 .] 275 301 .. 266 301 .. 0.89 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 3.7 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++ + f++ g +la+G++ g v i+ sp|Q9Y2T4-4|2ABG_HUMAN 20 ISTVEFNHTGELLATGDKGGRVVIF 44 68899***********988888875 PP == domain 2 score: 6.9 bits; conditional E-value: 0.75 EEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw...lasGsdDgtvriWd 38 ++ +++ p ++ l+s D+t+++W+ sp|Q9Y2T4-4|2ABG_HUMAN 85 INKIKWLPQQNAahsLLSTN-DKTIKLWK 112 66675444444466667656.*******6 PP == domain 3 score: 4.4 bits; conditional E-value: 4.6 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 GH +++s+++++d +s++ D + +W sp|Q9Y2T4-4|2ABG_HUMAN 163 NGHtYHINSISVNSDCETYMSAD-DLRINLW 192 499666****9555555545677.9999999 PP == domain 4 score: 9.7 bits; conditional E-value: 0.1 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ssv++++fs++g+++++ d tv++Wd sp|Q9Y2T4-4|2ABG_HUMAN 275 SSVSDVKFSHSGRYMLT-RDYLTVKVWD 301 4699999*********6.89*******9 PP >> tr|C9JQN1|C9JQN1_HUMAN WD repeat-containing protein 53 (Fragment) OS=Homo sapiens GN=WDR53 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.1 0.86 69 8 30 .. 7 29 .. 3 41 .. 0.72 2 ? 11.1 0.1 0.035 2.9 9 36 .. 90 120 .. 40 122 .. 0.85 3 ? 5.1 0.0 2.8 2.3e+02 2 31 .. 127 158 .. 126 160 .] 0.78 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.86 ESS.SSEEEEEEETTSSEEEEEET CS WD40 8 tGH.ssvtslafspdgawlasGsd 30 GH s+v +l s++g + asG + tr|C9JQN1|C9JQN1_HUMAN 7 GGHsSPVLCLNASKEGLL-ASGAE 29 49*888****88888877.78853 PP == domain 2 score: 11.1 bits; conditional E-value: 0.035 SS.SS..EEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ss..vtslafspdgawlasGsdDgtvri 36 H + +++l+ ++ ++las++d g ++i tr|C9JQN1|C9JQN1_HUMAN 90 FHvNEeeINCLSLNQTENLLASADDSGAIKI 120 3454467999999999999999998999988 PP == domain 3 score: 5.1 bits; conditional E-value: 2.8 EEEEEEESSSSE.EEEEEETTSSE.EEEEETT CS WD40 2 qclrtltGHssv.tslafspdgaw.lasGsdD 31 + +r+l+ Hs++ +s+af p + l+s++ D tr|C9JQN1|C9JQN1_HUMAN 127 KVIRSLKRHSNIcSSVAFRPQRPQsLVSCGLD 158 568999***77879**9988888876777755 PP >> tr|E9PJK2|E9PJK2_HUMAN Polycomb protein EED OS=Homo sapiens GN=EED PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.4 0.0 5.4e-07 4.4e-05 2 38 .] 181 219 .. 180 219 .. 0.89 2 ? 7.5 1.0 0.49 39 5 38 .] 322 358 .. 319 358 .. 0.82 Alignments for each domain: == domain 1 score: 26.4 bits; conditional E-value: 5.4e-07 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 qc++++ GH + ++ l+f+p + l+ s s+D+ +r+W+ tr|E9PJK2|E9PJK2_HUMAN 181 QCIKHYVGHgNAINELKFHPRDPNLLlSVSKDHALRLWN 219 8********999*****888888864499*********8 PP == domain 2 score: 7.5 bits; conditional E-value: 0.49 EEEESS.SS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ss..vtslafspdgawlasGsdDgtvriWd 38 +tlt H ++ ++ +fs+d++ l++ +dD ++ Wd tr|E9PJK2|E9PJK2_HUMAN 322 TTLTHHkCGaaIRQTSFSRDSSILIAVCDDASIWRWD 358 5788885448899999*******998888*9998887 PP >> tr|H0YNW7|H0YNW7_HUMAN Guanine nucleotide-binding protein subunit beta-5 OS=Homo sapiens GN=GNB5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.3 0.2 7e-09 5.6e-07 3 38 .] 55 91 .. 53 91 .. 0.94 Alignments for each domain: == domain 1 score: 32.3 bits; conditional E-value: 7e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + rtl+GH + v ++++++d++ ++s+s Dg+v +Wd tr|H0YNW7|H0YNW7_HUMAN 55 TRRTLKGHgNKVLCMDWCKDKRRIVSSSQDGKVIVWD 91 6799****888*************************9 PP >> tr|D6RCL6|D6RCL6_HUMAN Coatomer subunit beta' (Fragment) OS=Homo sapiens GN=COPB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 0.0048 0.39 13 38 .] 31 56 .. 18 56 .. 0.80 2 ! 13.1 0.0 0.0081 0.66 3 25 .. 62 85 .. 60 86 .] 0.86 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.0048 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v++ +f ++w+++G dD +r+++ tr|D6RCL6|D6RCL6_HUMAN 31 VRAAKFVARKNWVVTGADDMQIRVFN 56 7777799999**************97 PP == domain 2 score: 13.1 bits; conditional E-value: 0.0081 EEEEEESSSS.EEEEEEETTSSEE CS WD40 3 clrtltGHss.vtslafspdgawl 25 ++ +++Hs+ ++++a++p ++++ tr|D6RCL6|D6RCL6_HUMAN 62 RVHMFEAHSDyIRCIAVHPTQPFI 85 5899****556*********9997 PP >> sp|Q8NFH3|NUP43_HUMAN Nucleoporin Nup43 OS=Homo sapiens GN=NUP43 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.1 0.00026 0.021 5 38 .] 211 246 .. 207 246 .. 0.83 2 ? 10.5 0.1 0.054 4.4 6 38 .] 256 290 .. 252 290 .. 0.84 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 0.00026 EEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 +ltG + ++++ +p+++ ++ +G+ Dg + iWd sp|Q8NFH3|NUP43_HUMAN 211 LSLTGDrVPLHCVDRHPNQQHVVaTGGQDGMLSIWD 246 56777755679**********75499*********9 PP == domain 2 score: 10.5 bits; conditional E-value: 0.054 EEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 l++H + + f+p+++ l+++s+Dg++ Wd sp|Q8NFH3|NUP43_HUMAN 256 LLKAHeAEMWEVHFHPSNPEhLFTCSEDGSLWHWD 290 57889766899999******446***********8 PP >> sp|Q9H808-2|TLE6_HUMAN Isoform 2 of Transducin-like enhancer protein 6 OS=Homo sapiens GN=TLE6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 8.2 6.6e+02 21 38 .] 267 284 .. 247 284 .. 0.72 2 ? 11.1 0.1 0.037 3 4 31 .. 370 399 .. 367 405 .. 0.77 3 ? 9.5 0.0 0.11 9.1 11 29 .. 420 438 .. 410 445 .. 0.86 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.2 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 d ++ +++ g vriWd sp|Q9H808-2|TLE6_HUMAN 267 DANLAFASFTSGVVRIWD 284 44444567669******9 PP == domain 2 score: 11.1 bits; conditional E-value: 0.037 EEEEESS.SS.EEEEEEETTSSEEEEEETT CS WD40 4 lrtltGH.ss.vtslafspdgawlasGsdD 31 +r+ G+ +s + s++fsp g+w as ++D sp|Q9H808-2|TLE6_HUMAN 370 QRHMVGQkDSvILSVKFSPFGQWWASVGMD 399 788899955567***********7764445 PP == domain 3 score: 9.5 bits; conditional E-value: 0.11 SSEEEEEEETTSSEEEEEE CS WD40 11 ssvtslafspdgawlasGs 29 s+vt++++s++++++++Gs sp|Q9H808-2|TLE6_HUMAN 420 SPVTCCDVSSNNRLVVTGS 438 57****************8 PP >> tr|K7EP88|K7EP88_HUMAN Nucleoporin SEH1 (Fragment) OS=Homo sapiens GN=SEH1L PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.4 0.0088 0.72 10 35 .. 11 37 .. 5 38 .. 0.91 2 ? 11.6 0.6 0.026 2.1 6 37 .. 35 69 .. 34 70 .. 0.81 3 ? 12.9 0.0 0.01 0.81 11 37 .. 97 125 .. 79 126 .. 0.76 4 ? 5.2 0.7 2.6 2.1e+02 13 32 .. 148 172 .. 134 173 .. 0.75 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0088 SSS.EEEEEEETTSSEEEEEETTSEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvr 35 H++ +++++f+ +g+ +a++s D++v+ tr|K7EP88|K7EP88_HUMAN 11 HKDlIHDVSFDFHGRRMATCSSDQSVK 37 87789***************88***98 PP == domain 2 score: 11.6 bits; conditional E-value: 0.026 EEESS.SSEEEEEEETTSSE........EEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgaw........lasGsdDgtvriW 37 + ++H +sv+ + +w las+s D+t +W tr|K7EP88|K7EP88_HUMAN 35 SVKTHsGSVWRV------TWahpefgqvLASCSFDRTAAVW 69 56789777****......777777777799********999 PP == domain 3 score: 12.9 bits; conditional E-value: 0.01 SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 11 ssvtslafspdgaw..lasGsdDgtvriW 37 +svt+++f p + la++s Dg vri+ tr|K7EP88|K7EP88_HUMAN 97 TSVTDVKFAPKHMGlmLATCSADGIVRIY 125 459999766665555579**********8 PP == domain 4 score: 5.2 bits; conditional E-value: 2.6 EEEEEEETTSSE.....EEEEETTS CS WD40 13 vtslafspdgaw.....lasGsdDg 32 ++++++p+++ +a GsdD tr|K7EP88|K7EP88_HUMAN 148 CSCISWNPSSSRahspmIAVGSDDS 172 57999***999999998889*9885 PP >> sp|Q9UG01|IF172_HUMAN Intraflagellar transport protein 172 homolog OS=Homo sapiens GN=IFT172 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 0.016 1.3 12 38 .] 15 44 .. 3 44 .. 0.77 2 ? 5.6 0.0 2 1.6e+02 13 37 .. 69 93 .. 60 94 .. 0.86 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.016 S...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvriWd 38 + vt++a+s+++a +a ++ D+ v ++d sp|Q9UG01|IF172_HUMAN 15 GaakVTCMAWSQNNAKFAVCTVDRVVLLYD 44 1345***********************998 PP == domain 2 score: 5.6 bits; conditional E-value: 2 EEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 13 vtslafspdgawlasG.sdDgtvriW 37 v ++afspd++ +a G + D+ ++++ sp|Q9UG01|IF172_HUMAN 69 VKGMAFSPDSTKIAIGqT-DNIIYVY 93 7899************66.****998 PP >> sp|Q9UKT8-2|FBXW2_HUMAN Isoform 2 of F-box/WD repeat-containing protein 2 OS=Homo sapiens GN=FBXW2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.1 0.0011 0.089 6 37 .. 143 188 .. 140 188 .. 0.71 2 ! 13.8 0.1 0.0049 0.4 1 37 [. 193 239 .. 193 239 .. 0.78 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0011 EEESSSS..............EEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHss..............vtslafspdgawlasGsdDgtvriW 37 +l GHs v s++++++ + l+sGs D tv++W sp|Q9UKT8-2|FBXW2_HUMAN 143 SLIGHSArvyalyykdgllctVFSVDYNDELDILVSGSADFTVKVW 188 677884454444444555555667779999999************* PP == domain 2 score: 13.8 bits; conditional E-value: 0.0049 TEEEEEEESS.SSEEEEE..........EETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtsla..........fspdgawlasGsdDgtvriW 37 g+cl tltGH +vt + sp l+s++ + ++iW sp|Q9UKT8-2|FBXW2_HUMAN 193 GTCLNTLTGHtEWVTKVVlqkckvksllHSPGDYILLSAD-KYEIKIW 239 68********777887777777777884666666678877.******* PP >> tr|D6RD43|D6RD43_HUMAN Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (Fragment) OS=Homo sapiens # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 0.01 0.85 23 38 .] 6 21 .. 2 21 .. 0.86 2 ! 17.8 0.0 0.00028 0.023 3 38 .] 29 65 .. 27 65 .. 0.89 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.01 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++++++s Dg+v++W+ tr|D6RD43|D6RD43_HUMAN 6 DFIITASHDGHVKFWK 21 67999988*******6 PP == domain 2 score: 17.8 bits; conditional E-value: 0.00028 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++ H + + s+a+s++ga+++s +dD+ +++d tr|D6RD43|D6RD43_HUMAN 29 FVKHFRSHlGVIESIAVSSEGALFCSVGDDKAMKVFD 65 5899****6668************98899****9998 PP >> tr|F5GZ56|F5GZ56_HUMAN Intraflagellar transport protein 172 homolog OS=Homo sapiens GN=IFT172 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 7.8 6.3e+02 17 38 .] 2 23 .. 1 23 [. 0.92 2 ? 7.5 0.0 0.48 39 13 37 .. 48 72 .. 39 73 .. 0.86 3 ? 5.2 0.2 2.7 2.2e+02 7 34 .. 127 155 .. 121 156 .. 0.80 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 7.8 EEETTSSEEEEEETTSEEEEEE CS WD40 17 afspdgawlasGsdDgtvriWd 38 a+s+++a +a ++ D+ v ++d tr|F5GZ56|F5GZ56_HUMAN 2 AWSQNNAKFAVCTVDRVVLLYD 23 7999******9*9******998 PP == domain 2 score: 7.5 bits; conditional E-value: 0.48 EEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 13 vtslafspdgawlasG.sdDgtvriW 37 v ++afspd++ +a G + D+ ++++ tr|F5GZ56|F5GZ56_HUMAN 48 VKGMAFSPDSTKIAIGqT-DNIIYVY 72 7899************66.****998 PP == domain 3 score: 5.2 bits; conditional E-value: 2.7 EESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtv 34 + G s v sl ++ +g+ ++sG+ Dgt+ tr|F5GZ56|F5GZ56_HUMAN 127 IYGTeSYVVSLTTNCSGKGILSGHADGTI 155 446656688999999999999*******9 PP >> tr|K7EKG3|K7EKG3_HUMAN Echinoderm microtubule-associated protein-like 2 (Fragment) OS=Homo sapiens GN=EML2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.3 1.4 1.1e+02 17 37 .. 53 81 .. 31 82 .. 0.70 2 ? 7.7 0.0 0.43 35 7 37 .. 95 127 .. 89 127 .. 0.83 3 ! 16.5 0.1 0.00073 0.059 4 37 .. 136 170 .. 133 170 .. 0.89 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 1.4 E........EETTSSE.EEEEETTSEEEEE CS WD40 17 a........fspdgaw.lasGsdDgtvriW 37 + f+p + l++++ + ++++W tr|K7EKG3|K7EKG3_HUMAN 53 SneavlvatFHPTDPTvLITCG-KSHIYFW 81 155555556777777735699*.******* PP == domain 2 score: 7.7 bits; conditional E-value: 0.43 EESS.SS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ss..vtslafspdgawlasGsdDgtvriW 37 ++ H ++ v ++ f g+ + +G+ g++++W tr|K7EKG3|K7EKG3_HUMAN 95 FEKHeKPkyVLCVTFLEGGDVV-TGDSGGNLYVW 127 677987788****999999996.7*66******9 PP == domain 3 score: 16.5 bits; conditional E-value: 0.00073 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l +H ++v +l+ +dg++++ G++D+ v +W tr|K7EKG3|K7EKG3_HUMAN 136 QAVLGAHdGGVFGLCALRDGTLVSGGGRDRRVVLW 170 67899**777************97668******** PP >> tr|C9JTT6|C9JTT6_HUMAN Actin-related protein 2/3 complex subunit 1B (Fragment) OS=Homo sapiens GN=ARPC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 6.8 5.5e+02 12 37 .. 10 35 .. 3 36 .. 0.75 2 ! 27.5 0.2 2.4e-07 1.9e-05 2 37 .. 43 79 .. 42 80 .. 0.91 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.8 SEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 12 svtslafspdgawlasG.sdDgtvriW 37 ++++ a+++d + +a + ++ v+i+ tr|C9JTT6|C9JTT6_HUMAN 10 PISCHAWNKDRTQIAICpN-NHEVHIY 35 399*******999998767.7777776 PP == domain 2 score: 27.5 bits; conditional E-value: 2.4e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +++++l+ H++ vt++++ p+++ +++++ D++ ++W tr|C9JTT6|C9JTT6_HUMAN 43 TKVHELKEHNGqVTGIDWAPESNRIVTCGTDRNAYVW 79 689******555**************9999******* PP >> sp|Q6ZS81|WDFY4_HUMAN WD repeat- and FYVE domain-containing protein 4 OS=Homo sapiens GN=WDFY4 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.1 7.1e-05 0.0058 7 38 .] 2978 3010 .. 2973 3010 .. 0.90 2 ! 15.1 0.1 0.002 0.16 2 38 .] 3055 3100 .. 3054 3100 .. 0.73 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 7.1e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH + vt+la s ++l+sGs D+t+ +Wd sp|Q6ZS81|WDFY4_HUMAN 2978 LYGHtQAVTCLAASVTFSLLVSGSQDCTCILWD 3010 67**888*****99999***************9 PP == domain 2 score: 15.1 bits; conditional E-value: 0.002 EEEEEEESS.SS...EEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ss...vtsla......fspdgawlasGsdDgtvriWd 38 q+l ++t+ ++ +t+++ ++ ++ + +Gs Dg vr+W+ sp|Q6ZS81|WDFY4_HUMAN 3055 QPLASITTAwGPegaITCCClmegpaWDTSQIII-TGSQDGMVRVWK 3100 667777655434556*****77777777777765.8**********6 PP >> tr|Q96F32|Q96F32_HUMAN GNB5 protein OS=Homo sapiens GN=GNB5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.7 0.2 1.1e-08 9.1e-07 3 38 .] 55 91 .. 53 91 .. 0.94 Alignments for each domain: == domain 1 score: 31.7 bits; conditional E-value: 1.1e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + rtl+GH + v ++++++d++ ++s+s Dg+v +Wd tr|Q96F32|Q96F32_HUMAN 55 TRRTLKGHgNKVLCMDWCKDKRRIVSSSQDGKVIVWD 91 6799****888*************************9 PP >> tr|H3BNA2|H3BNA2_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.2 3.9e-07 3.1e-05 7 37 .. 77 109 .. 72 110 .. 0.86 2 ? 3.6 0.0 8.4 6.8e+02 2 19 .. 122 140 .. 121 147 .. 0.74 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 3.9e-07 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH +v ++a++p+++ + asGs+D+tv++W tr|H3BNA2|H3BNA2_HUMAN 77 VCGHtAPVLDIAWCPHNDNViASGSEDCTVMVW 109 559*888************73699********* PP == domain 2 score: 3.6 bits; conditional E-value: 8.4 EEEEEEESS.SSEEEEEEE CS WD40 2 qclrtltGH.ssvtslafs 19 +++ tl+GH + v +a++ tr|H3BNA2|H3BNA2_HUMAN 122 EPVVTLEGHtKRVGIVAWH 140 68899****8889777444 PP >> tr|K7EII6|K7EII6_HUMAN Echinoderm microtubule-associated protein-like 2 (Fragment) OS=Homo sapiens GN=EML2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.1 0.00052 0.042 4 37 .. 28 62 .. 25 62 .. 0.89 2 ! 14.4 1.3 0.0033 0.27 9 33 .. 156 180 .. 80 181 .] 0.91 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 0.00052 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +l +H ++v +l+ +dg++++ G++D+ v +W tr|K7EII6|K7EII6_HUMAN 28 QAVLGAHdGGVFGLCALRDGTLVSGGGRDRRVVLW 62 67899**777************97668******** PP == domain 2 score: 14.4 bits; conditional E-value: 0.0033 SSSSEEEEEEETTSSEEEEEETTSE CS WD40 9 GHssvtslafspdgawlasGsdDgt 33 G ++ ++fspdga+la Gs D+ tr|K7EII6|K7EII6_HUMAN 156 GNEQISVVSFSPDGAYLAVGSHDNL 180 333387889***********99985 PP >> sp|Q9Y2T4-3|2ABG_HUMAN Isoform 3 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isofor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 3.8 3e+02 13 37 .. 10 34 .. 4 35 .. 0.84 2 ? 7.0 0.0 0.73 59 13 38 .] 75 102 .. 53 102 .. 0.68 3 ? 4.5 0.1 4.5 3.6e+02 8 37 .. 153 182 .. 146 183 .. 0.70 4 ? 9.7 0.1 0.1 8.1 11 38 .] 265 291 .. 256 291 .. 0.89 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 3.8 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 ++ + f++ g +la+G++ g v i+ sp|Q9Y2T4-3|2ABG_HUMAN 10 ISTVEFNHTGELLATGDKGGRVVIF 34 68899***********988888875 PP == domain 2 score: 7.0 bits; conditional E-value: 0.73 EEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw...lasGsdDgtvriWd 38 ++ +++ p ++ l+s D+t+++W+ sp|Q9Y2T4-3|2ABG_HUMAN 75 INKIKWLPQQNAahsLLSTN-DKTIKLWK 102 66675444444466667656.*******6 PP == domain 3 score: 4.5 bits; conditional E-value: 4.5 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 GH +++s+++++d +s++ D + +W sp|Q9Y2T4-3|2ABG_HUMAN 153 NGHtYHINSISVNSDCETYMSAD-DLRINLW 182 499666****9555555545677.9999999 PP == domain 4 score: 9.7 bits; conditional E-value: 0.1 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ssv++++fs++g+++++ d tv++Wd sp|Q9Y2T4-3|2ABG_HUMAN 265 SSVSDVKFSHSGRYMLT-RDYLTVKVWD 291 4699999*********6.89*******9 PP >> sp|Q5TAQ9-2|DCAF8_HUMAN Isoform 2 of DDB1- and CUL4-associated factor 8 OS=Homo sapiens GN=DCAF8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 0.5 3e-08 2.4e-06 2 38 .] 184 221 .. 183 221 .. 0.93 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 3e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++ l+GH ++v+ l f++ g+wlasGsdD +v +Wd sp|Q5TAQ9-2|DCAF8_HUMAN 184 RLQHGLEGHtGCVNTLHFNQRGTWLASGSDDLKVVVWD 221 57899****777*************************9 PP >> tr|F5H0D2|F5H0D2_HUMAN Coronin OS=Homo sapiens GN=CORO1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.2 1.2e-06 9.7e-05 8 37 .. 79 110 .. 73 111 .. 0.86 2 ? 4.6 0.0 4.2 3.4e+02 3 25 .. 124 147 .. 122 154 .. 0.78 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.2e-06 ESS.SSEEEEEEETTSSEE.EEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGsdDgtvriW 37 GH ++v +++++p+++ + asGs+D+tv++W tr|F5H0D2|F5H0D2_HUMAN 79 CGHtGPVLDIDWCPHNDEViASGSEDCTVMVW 110 59*888************73699********* PP == domain 2 score: 4.6 bits; conditional E-value: 4.2 EEEEEESS.SSEEEEEEETTSSEE CS WD40 3 clrtltGH.ssvtslafspdgawl 25 ++ +l+GH + v +a++p + + tr|F5H0D2|F5H0D2_HUMAN 124 PVVVLEGHtKRVGIIAWHPTARNV 147 77899***999*999999998875 PP >> sp|Q99698|LYST_HUMAN Lysosomal-trafficking regulator OS=Homo sapiens GN=LYST PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 0.0015 0.12 3 38 .] 3608 3644 .. 3606 3644 .. 0.85 2 ? 4.5 0.2 4.5 3.6e+02 4 37 .. 3651 3689 .. 3648 3690 .. 0.67 3 ? 6.2 0.1 1.3 1.1e+02 7 38 .] 3695 3735 .. 3691 3735 .. 0.69 4 ? 5.4 0.1 2.2 1.8e+02 9 37 .. 3750 3778 .. 3739 3779 .. 0.76 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 0.0015 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +l GH +tsl +++ + l+s s+Dgt+ iWd sp|Q99698|LYST_HUMAN 3608 TQIHLYGHtEEITSLFVCKPYSILISVSRDGTCIIWD 3644 678999**666****9888888888899********9 PP == domain 2 score: 4.5 bits; conditional E-value: 4.5 EEEEESS.SSEEEEE.EETTSSE..EE..EEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgaw..la..sGsdDgtvriW 37 +++l GH s+vt+++ +g+ ++ +G+ +r+W sp|Q99698|LYST_HUMAN 3651 VQSLAGHkSPVTAVSaSETSGDIatVCdsAGG-GSDLRLW 3689 68999**888****875555555213232356.8888888 PP == domain 3 score: 6.2 bits; conditional E-value: 1.3 EESS.SS...EEEEEEETTSSE....EEEEE.TTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgaw....lasGs.dDgtvriWd 38 l GH + ++s+afs +++G+ ++g vr+W+ sp|Q99698|LYST_HUMAN 3695 LVGHvHCreiICSVAFSNQPEGvsinVIAGGlENGIVRLWS 3735 568852358789998544444444665778868*******5 PP == domain 4 score: 5.4 bits; conditional E-value: 2.2 SSSSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 9 GHssvtslafspdgawlasG.sdDgtvriW 37 +++ sl fs dg+ l ++ s Dgtv W sp|Q99698|LYST_HUMAN 3750 SNKPIISLTFSCDGHHLYTAnS-DGTVIAW 3778 335677**************66.***9877 PP >> tr|H7C4N7|H7C4N7_HUMAN WD repeat domain phosphoinositide-interacting protein 4 (Fragment) OS=Homo sapiens GN=WDR45 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.033 2.7 6 34 .. 15 44 .. 10 49 .. 0.86 2 ! 18.9 0.0 0.00012 0.01 13 37 .. 68 92 .. 54 92 .. 0.84 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.033 EEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H s++ +++ ++ g+ +as+s +gt+ tr|H7C4N7|H7C4N7_HUMAN 15 TINAHqSDIACVSLNQPGTVVASASQKGTL 44 5569*999*****************88875 PP == domain 2 score: 18.9 bits; conditional E-value: 0.00012 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ fs+d+++l+++sd+gtv+i+ tr|H7C4N7|H7C4N7_HUMAN 68 LYCINFSHDSSFLCASSDKGTVHIF 92 79************99******996 PP >> tr|H0Y8I2|H0Y8I2_HUMAN Intraflagellar transport protein 122 homolog (Fragment) OS=Homo sapiens GN=IFT122 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.0 0.22 18 13 34 .. 2 32 .. 1 34 [. 0.77 2 ! 13.2 0.7 0.008 0.65 2 32 .. 31 66 .. 30 72 .. 0.79 3 ? 10.9 0.1 0.041 3.3 4 35 .. 75 109 .. 73 110 .] 0.77 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.22 EEEEEEETTSSE..EEEEET.......TSEE CS WD40 13 vtslafspdgaw..lasGsd.......Dgtv 34 ++++af pdg+ la+Gs+ Dgt+ tr|H0Y8I2|H0Y8I2_HUMAN 2 INDIAFKPDGTQliLAAGSRllvydtsDGTL 32 89**********5446998666666778876 PP == domain 2 score: 13.2 bits; conditional E-value: 0.008 EEEEEEESSSS......EEEEEEETTSSEEEEEETTS CS WD40 2 qclrtltGHss......vtslafspdgawlasGsdDg 32 ++l+ l+GH++ + +++++p + las+s tr|H0Y8I2|H0Y8I2_HUMAN 31 TLLQPLKGHKDtvhndaIQCVSYNPITHQLASCS-SS 66 6788999**6667888999************997.33 PP == domain 3 score: 10.9 bits; conditional E-value: 0.041 EEEEESS.SS..EEEEEEETTSSEEEEEETTSEEE CS WD40 4 lrtltGH.ss..vtslafspdgawlasGsdDgtvr 35 +++ + H ss + ++++ dg++la G+ +g + tr|H0Y8I2|H0Y8I2_HUMAN 75 QKSVSKHkSSskIICCSWTNDGQYLALGMFNGIIS 109 67788897447977**********98676677775 PP >> sp|Q8N3Y1-2|FBXW8_HUMAN Isoform 2 of F-box/WD repeat-containing protein 8 OS=Homo sapiens GN=FBXW8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.3 0.78 63 14 38 .] 148 170 .. 133 170 .. 0.73 2 ? 6.4 0.0 1.1 89 14 38 .] 370 395 .. 360 395 .. 0.75 3 ? 5.8 0.1 1.7 1.3e+02 6 38 .] 404 435 .. 399 435 .. 0.73 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.78 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 +++ s+dg + +G g vr+Wd sp|Q8N3Y1-2|FBXW8_HUMAN 148 CDV-HSHDGVVI-AGYTSGDVRVWD 170 555.66777776.5*88*******9 PP == domain 2 score: 6.4 bits; conditional E-value: 1.1 EEEEEETTSSEE.EEEETTSEEEEEE CS WD40 14 tslafspdgawl.asGsdDgtvriWd 38 t++ s++ + l +sG +Dg vri d sp|Q8N3Y1-2|FBXW8_HUMAN 370 TCVNLSDSPPNLmVSGNMDGRVRIHD 395 788766666665269988*****976 PP == domain 3 score: 5.8 bits; conditional E-value: 1.7 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +l++H v+++ ++ ++sG++ g v +Wd sp|Q8N3Y1-2|FBXW8_HUMAN 404 SLSAHqLRVSAV------QMddwkIVSGGEEGLVSVWD 435 577774447777......44444888***********9 PP >> sp|Q9P2H3-2|IFT80_HUMAN Isoform 2 of Intraflagellar transport protein 80 homolog OS=Homo sapiens GN=IFT80 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.4 0.027 2.2 6 38 .] 46 79 .. 41 79 .. 0.86 2 ? 12.3 0.0 0.015 1.2 10 29 .. 91 111 .. 82 121 .. 0.78 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.027 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++H++ + +++++ +++++s+++D++ ++Wd sp|Q9P2H3-2|IFT80_HUMAN 46 QWKAHDGiILKVDWNSVNDLILSAGEDCKYKVWD 79 4679955479**99999****************9 PP == domain 2 score: 12.3 bits; conditional E-value: 0.015 S.SSEEEEEEETTSSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGs 29 H ++ts+a+ pdg ++a Gs sp|Q9P2H3-2|IFT80_HUMAN 91 HeHPITSVAWAPDGELFAVGS 111 4338**************998 PP >> sp|Q6ZQQ6|WDR87_HUMAN WD repeat-containing protein 87 OS=Homo sapiens GN=WDR87 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 0.01 0.82 2 38 .] 235 272 .. 234 272 .. 0.87 2 ! 16.6 0.1 0.00067 0.054 10 38 .] 566 595 .. 557 595 .. 0.80 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.01 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+++ +H s+v +++ p+ + l++++ D ++ W+ sp|Q6ZQQ6|WDR87_HUMAN 235 HPLHSFQAHqSGVICIRSRPEAHTLLTAGSDSLIKEWN 272 699******88888**********986544*****997 PP == domain 2 score: 16.6 bits; conditional E-value: 0.00067 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H + +ts++++ + +++++Gs Dg+vriWd sp|Q6ZQQ6|WDR87_HUMAN 566 HlCAITSFDVCLSLSLFVTGSADGSVRIWD 595 777788777777778899***********9 PP >> tr|E7ESW6|E7ESW6_HUMAN WD repeat-containing protein 87 OS=Homo sapiens GN=WDR87 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 0.01 0.83 2 38 .] 274 311 .. 273 311 .. 0.87 2 ! 16.6 0.1 0.00068 0.055 10 38 .] 605 634 .. 596 634 .. 0.80 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.01 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+++ +H s+v +++ p+ + l++++ D ++ W+ tr|E7ESW6|E7ESW6_HUMAN 274 HPLHSFQAHqSGVICIRSRPEAHTLLTAGSDSLIKEWN 311 699******88888**********986544*****997 PP == domain 2 score: 16.6 bits; conditional E-value: 0.00068 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H + +ts++++ + +++++Gs Dg+vriWd tr|E7ESW6|E7ESW6_HUMAN 605 HlCAITSFDVCLSLSLFVTGSADGSVRIWD 634 777788777777778899***********9 PP >> sp|Q6ZQQ6-2|WDR87_HUMAN Isoform 2 of WD repeat-containing protein 87 OS=Homo sapiens GN=WDR87 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 0.01 0.83 2 38 .] 274 311 .. 273 311 .. 0.87 2 ! 16.6 0.1 0.00068 0.055 10 38 .] 605 634 .. 596 634 .. 0.80 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.01 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+++ +H s+v +++ p+ + l++++ D ++ W+ sp|Q6ZQQ6-2|WDR87_HUMAN 274 HPLHSFQAHqSGVICIRSRPEAHTLLTAGSDSLIKEWN 311 699******88888**********986544*****997 PP == domain 2 score: 16.6 bits; conditional E-value: 0.00068 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H + +ts++++ + +++++Gs Dg+vriWd sp|Q6ZQQ6-2|WDR87_HUMAN 605 HlCAITSFDVCLSLSLFVTGSADGSVRIWD 634 777788777777778899***********9 PP >> sp|A4D1P6-2|WDR91_HUMAN Isoform 2 of WD repeat-containing protein 91 OS=Homo sapiens GN=WDR91 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.2 0.086 7 7 38 .] 404 436 .. 400 436 .. 0.84 2 ! 16.1 0.0 0.00095 0.077 13 37 .. 565 589 .. 552 590 .. 0.86 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.086 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H ss+ +++++ +g+ +as + Dg +++W+ sp|A4D1P6-2|WDR91_HUMAN 404 YGEHhSSIMHCRVDCSGRRVASLDVDGVIKVWS 436 6667799************975478*******5 PP == domain 2 score: 16.1 bits; conditional E-value: 0.00095 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ af+++g++l++G Dg +r++ sp|A4D1P6-2|WDR91_HUMAN 565 INCTAFNHNGNLLVTGAADGVIRLF 589 89**************99*****96 PP >> sp|Q6ZS81-4|WDFY4_HUMAN Isoform 4 of WD repeat- and FYVE domain-containing protein 4 OS=Homo sapiens GN=WDFY4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.1 7.1e-05 0.0057 7 38 .] 2978 3010 .. 2973 3010 .. 0.90 2 ! 15.1 0.1 0.002 0.16 2 38 .] 3055 3100 .. 3054 3100 .. 0.73 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 7.1e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH + vt+la s ++l+sGs D+t+ +Wd sp|Q6ZS81-4|WDFY4_HUMAN 2978 LYGHtQAVTCLAASVTFSLLVSGSQDCTCILWD 3010 67**888*****99999***************9 PP == domain 2 score: 15.1 bits; conditional E-value: 0.002 EEEEEEESS.SS...EEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ss...vtsla......fspdgawlasGsdDgtvriWd 38 q+l ++t+ ++ +t+++ ++ ++ + +Gs Dg vr+W+ sp|Q6ZS81-4|WDFY4_HUMAN 3055 QPLASITTAwGPegaITCCClmegpaWDTSQIII-TGSQDGMVRVWK 3100 667777655434556*****77777777777765.8**********6 PP >> tr|H3BTV8|H3BTV8_HUMAN Katanin p80 WD40 repeat-containing subunit B1 (Fragment) OS=Homo sapiens GN=KATNB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.1 7.8e-05 0.0063 4 38 .] 13 49 .. 10 49 .. 0.88 2 ? 10.4 0.0 0.061 4.9 2 16 .. 54 69 .. 53 78 .. 0.87 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 7.8e-05 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 l+++ +H s+v+sl +g++la+G+dD+ v +W+ tr|H3BTV8|H3BTV8_HUMAN 13 LQEIVAHaSNVSSLVlGKASGRLLATGGDDCRVNLWS 49 667779*888*999999999****************5 PP == domain 2 score: 10.4 bits; conditional E-value: 0.061 EEEEEEESS.SSEEEE CS WD40 2 qclrtltGH.ssvtsl 16 +c+ +ltGH s+v s+ tr|H3BTV8|H3BTV8_HUMAN 54 NCIMSLTGHtSPVESV 69 79*******999*999 PP >> tr|C9JBJ7|C9JBJ7_HUMAN Actin-related protein 2/3 complex subunit 1B (Fragment) OS=Homo sapiens GN=ARPC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.2 3.8e-07 3.1e-05 2 37 .. 43 79 .. 42 80 .. 0.91 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 3.8e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +++++l+ H++ vt++++ p+++ +++++ D++ ++W tr|C9JBJ7|C9JBJ7_HUMAN 43 TKVHELKEHNGqVTGIDWAPESNRIVTCGTDRNAYVW 79 689******555**************9999******* PP >> tr|C9K057|C9K057_HUMAN Actin-related protein 2/3 complex subunit 1B (Fragment) OS=Homo sapiens GN=ARPC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.7 0.2 4.3e-07 3.5e-05 2 37 .. 43 79 .. 42 80 .. 0.91 Alignments for each domain: == domain 1 score: 26.7 bits; conditional E-value: 4.3e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +++++l+ H++ vt++++ p+++ +++++ D++ ++W tr|C9K057|C9K057_HUMAN 43 TKVHELKEHNGqVTGIDWAPESNRIVTCGTDRNAYVW 79 689******555**************9999******* PP >> sp|P57081-2|WDR4_HUMAN Isoform 2 of tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 OS=Homo sapien # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.069 5.6 9 36 .. 143 171 .. 133 173 .. 0.86 2 ! 14.1 0.0 0.0042 0.34 9 37 .. 186 216 .. 178 217 .. 0.66 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.069 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 GH s ++a+spd ++++++++D ++r+ sp|P57081-2|WDR4_HUMAN 143 GHlSMLLDVAVSPDDRFILTADRDEKIRV 171 88555789*******************98 PP == domain 2 score: 14.1 bits; conditional E-value: 0.0042 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 GH +v+ +++ p ++ l+s+s Dgt+r+W sp|P57081-2|WDR4_HUMAN 186 GHtEFVSRISVVPTQPGlLLSSSGDGTLRLW 216 897668888755555552335544******* PP >> tr|Q5SVS3|Q5SVS3_HUMAN F-box/WD repeat-containing protein 4 (Fragment) OS=Homo sapiens GN=FBXW4 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.2 0.031 2.5 2 34 .. 67 98 .. 66 102 .. 0.83 2 ! 19.5 0.1 8e-05 0.0064 6 37 .. 110 140 .. 105 140 .. 0.86 3 ? 3.5 1.6 9.3 7.6e+02 1 28 [. 148 175 .. 148 189 .. 0.81 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.031 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtv 34 ++l+++ GH +v+++ + +++ +++G+ Dg++ tr|Q5SVS3|Q5SVS3_HUMAN 67 RPLGVFAGHdEDVCHF-VLANSHIVSAGG-DGKI 98 7899*****888*777.888888899999.**98 PP == domain 2 score: 19.5 bits; conditional E-value: 8e-05 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++H + v+++ + g ++sGs+D+t ++W tr|Q5SVS3|Q5SVS3_HUMAN 110 KYSAHeQEVNCV--DCKGGIIVSGSRDRTAKVW 140 589**888****..66667799*********** PP == domain 3 score: 3.5 bits; conditional E-value: 9.3 TEEEEEEESSSSEEEEEEETTSSEEEEE CS WD40 1 gqclrtltGHssvtslafspdgawlasG 28 gqcl+t+ + + v+s+a sp + +++G tr|Q5SVS3|Q5SVS3_HUMAN 148 GQCLHTIQTEDRVWSIAISPLLSSFVTG 175 79****988777****999877766666 PP >> sp|P57081|WDR4_HUMAN tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 OS=Homo sapiens GN=WDR4 PE=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.069 5.6 9 36 .. 143 171 .. 133 173 .. 0.86 2 ! 14.1 0.0 0.0042 0.34 9 37 .. 186 216 .. 178 217 .. 0.66 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.069 SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvri 36 GH s ++a+spd ++++++++D ++r+ sp|P57081|WDR4_HUMAN 143 GHlSMLLDVAVSPDDRFILTADRDEKIRV 171 88555789*******************98 PP == domain 2 score: 14.1 bits; conditional E-value: 0.0042 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 GH +v+ +++ p ++ l+s+s Dgt+r+W sp|P57081|WDR4_HUMAN 186 GHtEFVSRISVVPTQPGlLLSSSGDGTLRLW 216 897668888755555552335544******* PP >> tr|C9JSB1|C9JSB1_HUMAN Intraflagellar transport protein 80 homolog (Fragment) OS=Homo sapiens GN=IFT80 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.1 0.19 15 10 38 .] 13 41 .. 5 41 .. 0.81 2 ? 12.2 0.0 0.016 1.3 6 38 .] 101 134 .. 96 134 .. 0.75 3 ? 4.5 0.0 4.4 3.6e+02 10 29 .. 146 167 .. 137 172 .. 0.72 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.19 SSS.EEEEEEETTSSE.....EEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgaw.....lasGsdDgtvriWd 38 H+ v+++ w l s+sdD+ + W+ tr|C9JSB1|C9JSB1_HUMAN 13 HQElVSCV------GWttaeeLYSCSDDHQIVKWN 41 64469999......898888889********9997 PP == domain 2 score: 12.2 bits; conditional E-value: 0.016 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + ++H + v + +++ +g+ l++ ++Dg ++iW+ tr|C9JSB1|C9JSB1_HUMAN 101 SVEAHcGAVLAGRWNYEGTALVTVGEDGQIKIWS 134 55667444666668889999999999*******5 PP == domain 3 score: 4.5 bits; conditional E-value: 4.4 S.SSEEEEEEETTSSEEE.EEE CS WD40 10 H.ssvtslafspdgawla.sGs 29 + ++v+s+a+ pd+ ++ +++ tr|C9JSB1|C9JSB1_HUMAN 146 QgTPVYSVAWGPDSEKVLyTAG 167 3457*********988644555 PP >> tr|F5H2L7|F5H2L7_HUMAN WD repeat and SOCS box-containing protein 2 OS=Homo sapiens GN=WSB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 0.0 1.4e-07 1.2e-05 3 32 .. 21 51 .. 19 52 .. 0.91 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 1.4e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTS CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDg 32 ++r+l+GH ssv s++fspd+a+l+++s+D tr|F5H2L7|F5H2L7_HUMAN 21 LIRKLEGHqSSVVSCDFSPDSALLVTASYDT 51 6899****99999**************9886 PP >> sp|Q9C0C7-6|AMRA1_HUMAN Isoform 6 of Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens GN=A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.0 4.2 3.4e+02 16 36 .. 59 79 .. 58 80 .. 0.92 2 ! 22.7 1.0 7.9e-06 0.00064 1 38 [] 85 124 .. 85 124 .. 0.74 3 ? 3.5 0.1 8.9 7.2e+02 11 38 .] 138 164 .. 128 164 .. 0.84 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 4.2 EEEETTSSEEEEEETTSEEEE CS WD40 16 lafspdgawlasGsdDgtvri 36 lafspd ++las + +++++i sp|Q9C0C7-6|AMRA1_HUMAN 59 LAFSPDRTLLASTHVNHNIYI 79 68*********9999999987 PP == domain 2 score: 22.7 bits; conditional E-value: 7.9e-06 TEEEEEEESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+++l GH + +++ f+p + +asG+ Dg vriWd sp|Q9C0C7-6|AMRA1_HUMAN 85 GKCVHSLIGHrrT-PWCVTFHPTISGlIASGCLDGEVRIWD 124 79********844.4666444444443789999*******9 PP == domain 3 score: 3.5 bits; conditional E-value: 8.9 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 + + slaf+p ++l+ ++ + +++Wd sp|Q9C0C7-6|AMRA1_HUMAN 138 NAIASLAFHPTAQLLLIAT-ANEIHFWD 164 4599**********99899.89999998 PP >> tr|F8VUB6|F8VUB6_HUMAN Aladin (Fragment) OS=Homo sapiens GN=AAAS PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.1 5.2e-06 0.00042 6 38 .] 207 240 .. 202 240 .. 0.87 2 ? 4.0 0.0 6.5 5.3e+02 12 27 .. 256 271 .. 249 275 .. 0.82 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 5.2e-06 EEESSSSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 6 tltGHssvtslafspdgawlasGs.dDgtvriWd 38 + GH++vtsla+ p+g l+s+s D +r+Wd tr|F8VUB6|F8VUB6_HUMAN 207 SHPGHTPVTSLAWAPSGGRLLSASpVDAAIRVWD 240 3359*99****************999*******9 PP == domain 2 score: 4.0 bits; conditional E-value: 6.5 SEEEEEEETTSSEEEE CS WD40 12 svtslafspdgawlas 27 +vt l +spdg+ +++ tr|F8VUB6|F8VUB6_HUMAN 256 GVTNLLWSPDGSKILA 271 59*********98764 PP >> tr|F5H050|F5H050_HUMAN Cytoplasmic dynein 1 intermediate chain 1 OS=Homo sapiens GN=DYNC1I1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 5.1 4.1e+02 7 38 .] 243 288 .. 238 288 .. 0.67 2 ? 9.5 0.0 0.11 9 7 38 .] 298 332 .. 292 332 .. 0.81 3 ! 13.5 0.3 0.0064 0.52 6 37 .. 442 480 .. 439 481 .. 0.78 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 5.1 EESS..SS..EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 7 ltGH..ss..vtslafspdgawlasGsd..........DgtvriWd 38 ++ H ++ vt++++s + l+ +s+ Dg +W+ tr|F5H050|F5H050_HUMAN 243 YDEHwsKHrvVTCMDWSLQYPELMVASYnnnedaphepDGVALVWN 288 66787444878***77666666766665455667777777777776 PP == domain 2 score: 9.5 bits; conditional E-value: 0.11 EESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgawlasGs.dDgtvriWd 38 + H ssv s++f + ++ l+ G+ + g + +Wd tr|F5H050|F5H050_HUMAN 298 YVFHcqSSVMSVCFARFHPNLVVGGtYSGQIVLWD 332 55676577*****99999999988548*******9 PP == domain 3 score: 13.5 bits; conditional E-value: 0.0064 EEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 +++GH ++vt++ + ++ ++ ++s D tv++W tr|F5H050|F5H050_HUMAN 442 VFEGHqGPVTGINchmavgpIDFSHLFV-TSSFDWTVKLW 480 689**88899997777888766666666.5666******* PP >> sp|O14576-3|DC1I1_HUMAN Isoform 3 of Cytoplasmic dynein 1 intermediate chain 1 OS=Homo sapiens GN=DYNC1I1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 5.2 4.2e+02 7 38 .] 243 288 .. 238 288 .. 0.67 2 ? 9.5 0.0 0.11 9.1 7 38 .] 298 332 .. 292 332 .. 0.81 3 ! 13.5 0.3 0.0064 0.52 6 37 .. 442 480 .. 439 481 .. 0.78 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 5.2 EESS..SS..EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 7 ltGH..ss..vtslafspdgawlasGsd..........DgtvriWd 38 ++ H ++ vt++++s + l+ +s+ Dg +W+ sp|O14576-3|DC1I1_HUMAN 243 YDEHwsKHrvVTCMDWSLQYPELMVASYnnnedaphepDGVALVWN 288 66787444878***77666666766665455667777777777776 PP == domain 2 score: 9.5 bits; conditional E-value: 0.11 EESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgawlasGs.dDgtvriWd 38 + H ssv s++f + ++ l+ G+ + g + +Wd sp|O14576-3|DC1I1_HUMAN 298 YVFHcqSSVMSVCFARFHPNLVVGGtYSGQIVLWD 332 55676577*****99999999988548*******9 PP == domain 3 score: 13.5 bits; conditional E-value: 0.0064 EEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 +++GH ++vt++ + ++ ++ ++s D tv++W sp|O14576-3|DC1I1_HUMAN 442 VFEGHqGPVTGINchmavgpIDFSHLFV-TSSFDWTVKLW 480 689**88899997777888766666666.5666******* PP >> tr|E9PBK6|E9PBK6_HUMAN WD repeat-containing protein 6 OS=Homo sapiens GN=WDR6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 8 6.5e+02 20 37 .. 322 339 .. 305 339 .. 0.74 2 ! 13.1 0.2 0.0085 0.69 2 37 .. 419 458 .. 418 459 .. 0.76 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 8 TTSSEEE.EEETTSEEEEE CS WD40 20 pdgawla.sGsdDgtvriW 37 g+++a ++s Dg vr++ tr|E9PBK6|E9PBK6_HUMAN 322 GLGPLVAaACS-DGAVRLF 339 55788872557.*****85 PP == domain 2 score: 13.1 bits; conditional E-value: 0.0085 EEEEEEESS.SSEEEEE..EETTSSE.EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgaw.lasGsdDgtvriW 37 ++ tl +H ++++sl ++g+ +asGs+Dg+++++ tr|E9PBK6|E9PBK6_HUMAN 419 TPSLTLQAHsCGINSLHtlPTREGHHlVASGSEDGSLHVF 458 5678999**777****887555555535799******986 PP >> sp|Q8N3Y1|FBXW8_HUMAN F-box/WD repeat-containing protein 8 OS=Homo sapiens GN=FBXW8 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.3 0.9 73 14 38 .] 214 236 .. 199 236 .. 0.73 2 ? 6.2 0.0 1.3 1e+02 14 38 .] 436 461 .. 426 461 .. 0.75 3 ? 5.6 0.1 1.9 1.6e+02 6 38 .] 470 501 .. 465 501 .. 0.73 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.9 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 +++ s+dg + +G g vr+Wd sp|Q8N3Y1|FBXW8_HUMAN 214 CDV-HSHDGVVI-AGYTSGDVRVWD 236 455.66777776.5*88*******9 PP == domain 2 score: 6.2 bits; conditional E-value: 1.3 EEEEEETTSSEE.EEEETTSEEEEEE CS WD40 14 tslafspdgawl.asGsdDgtvriWd 38 t++ s++ + l +sG +Dg vri d sp|Q8N3Y1|FBXW8_HUMAN 436 TCVNLSDSPPNLmVSGNMDGRVRIHD 461 788766666665269988*****976 PP == domain 3 score: 5.6 bits; conditional E-value: 1.9 EEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 +l++H v+++ ++ ++sG++ g v +Wd sp|Q8N3Y1|FBXW8_HUMAN 470 SLSAHqLRVSAV------QMddwkIVSGGEEGLVSVWD 501 577774447777......44444888***********9 PP >> tr|E7EMZ0|E7EMZ0_HUMAN DmX-like protein 1 (Fragment) OS=Homo sapiens GN=DMXL1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.5 0.00061 0.05 1 37 [. 159 196 .. 159 196 .. 0.87 2 ? 10.8 0.1 0.044 3.6 7 37 .. 227 267 .. 222 268 .. 0.81 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 0.00061 TEEEEEEESSSSEEEEEEETTSSEEEEEE.TTSEEEEE CS WD40 1 gqclrtltGHssvtslafspdgawlasGs.dDgtvriW 37 ++c++++++ s v+ ++fspdg ++a+++ dD+ +++W tr|E7EMZ0|E7EMZ0_HUMAN 159 WKCIWHCKTASQVHLMKFSPDGEFFATAGkDDCLLKVW 196 68899998887798889*********88757******* PP == domain 2 score: 10.8 bits; conditional E-value: 0.044 EESS.SSEEEEEEETTSSE.........EEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgaw.........lasGsdDgtvriW 37 + +H v+++++ + +++ l+++++D+ +r+W tr|E7EMZ0|E7EMZ0_HUMAN 227 YLAHpRAVNGFSWRKTSKYmprasvcnvLLTCCKDNVCRLW 267 5578555999988888888888888888889********** PP >> tr|G5E9K1|G5E9K1_HUMAN Cytoplasmic dynein 1 intermediate chain 1 OS=Homo sapiens GN=DYNC1I1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 5.3 4.3e+02 7 38 .] 260 305 .. 255 305 .. 0.67 2 ? 9.5 0.0 0.12 9.4 7 38 .] 315 349 .. 309 349 .. 0.81 3 ! 13.4 0.3 0.0067 0.54 6 37 .. 459 497 .. 456 498 .. 0.78 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 5.3 EESS..SS..EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 7 ltGH..ss..vtslafspdgawlasGsd..........DgtvriWd 38 ++ H ++ vt++++s + l+ +s+ Dg +W+ tr|G5E9K1|G5E9K1_HUMAN 260 YDEHwsKHrvVTCMDWSLQYPELMVASYnnnedaphepDGVALVWN 305 66787444878***77666666766665455667777777777776 PP == domain 2 score: 9.5 bits; conditional E-value: 0.12 EESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgawlasGs.dDgtvriWd 38 + H ssv s++f + ++ l+ G+ + g + +Wd tr|G5E9K1|G5E9K1_HUMAN 315 YVFHcqSSVMSVCFARFHPNLVVGGtYSGQIVLWD 349 55676577*****99999999988548*******9 PP == domain 3 score: 13.4 bits; conditional E-value: 0.0067 EEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 +++GH ++vt++ + ++ ++ ++s D tv++W tr|G5E9K1|G5E9K1_HUMAN 459 VFEGHqGPVTGINchmavgpIDFSHLFV-TSSFDWTVKLW 497 689**88899997777888766666666.5666******* PP >> sp|O14576-2|DC1I1_HUMAN Isoform 2 of Cytoplasmic dynein 1 intermediate chain 1 OS=Homo sapiens GN=DYNC1I1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 5.4 4.4e+02 7 38 .] 263 308 .. 258 308 .. 0.67 2 ? 9.5 0.0 0.12 9.5 7 38 .] 318 352 .. 312 352 .. 0.81 3 ! 13.4 0.3 0.0067 0.54 6 37 .. 462 500 .. 459 501 .. 0.78 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 5.4 EESS..SS..EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 7 ltGH..ss..vtslafspdgawlasGsd..........DgtvriWd 38 ++ H ++ vt++++s + l+ +s+ Dg +W+ sp|O14576-2|DC1I1_HUMAN 263 YDEHwsKHrvVTCMDWSLQYPELMVASYnnnedaphepDGVALVWN 308 66787444878***77666666766665455667777777777776 PP == domain 2 score: 9.5 bits; conditional E-value: 0.12 EESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgawlasGs.dDgtvriWd 38 + H ssv s++f + ++ l+ G+ + g + +Wd sp|O14576-2|DC1I1_HUMAN 318 YVFHcqSSVMSVCFARFHPNLVVGGtYSGQIVLWD 352 55676577*****99999999988548*******9 PP == domain 3 score: 13.4 bits; conditional E-value: 0.0067 EEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 +++GH ++vt++ + ++ ++ ++s D tv++W sp|O14576-2|DC1I1_HUMAN 462 VFEGHqGPVTGINchmavgpIDFSHLFV-TSSFDWTVKLW 500 689**88899997777888766666666.5666******* PP >> sp|Q5VW00|DC122_HUMAN DDB1- and CUL4-associated factor 12-like protein 2 OS=Homo sapiens GN=DCAF12L2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 1 83 9 31 .. 146 170 .. 141 172 .. 0.84 2 ! 16.0 1.6 0.001 0.082 6 37 .. 189 220 .. 185 221 .. 0.74 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 1 SS..SSEEEEEEETTSSEEEEEETT CS WD40 9 GH..ssvtslafspdgawlasGsdD 31 +H ++++++ +p++++la+G+++ sp|Q5VW00|DC122_HUMAN 146 AHqgCGIHAIELNPSKTLLATGGEN 170 786445****************965 PP == domain 2 score: 16.0 bits; conditional E-value: 0.001 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 GH +++ ++a+ +d +sGs+Dgtv +W sp|Q5VW00|DC122_HUMAN 189 DRHGHkDWIFAVAWLSDTVA-VSGSRDGTVALW 220 556**666****55555554.48********** PP >> sp|Q9H6Y2-2|WDR55_HUMAN Isoform 2 of WD repeat-containing protein 55 OS=Homo sapiens GN=WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 3.7 3e+02 15 35 .. 47 59 .. 35 60 .. 0.81 2 ! 20.2 0.0 4.7e-05 0.0038 5 38 .] 70 105 .. 66 105 .. 0.82 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 3.7 EEEEETTSSEEEEEETTSEEE CS WD40 15 slafspdgawlasGsdDgtvr 35 sl l++Gs Dg +r sp|Q9H6Y2-2|WDR55_HUMAN 47 SL--------LCTGSTDGVIR 59 45........99*******98 PP == domain 2 score: 20.2 bits; conditional E-value: 4.7e-05 EEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 ++ H +v la s+ g++las++ D+ +++Wd sp|Q9H6Y2-2|WDR55_HUMAN 70 GSVGQHtgEPVEELALSHCGRFLASSGHDQRLKFWD 105 5666785444**************8777*******9 PP >> tr|B4DP38|B4DP38_HUMAN Methylosome protein 50 OS=Homo sapiens GN=WDR77 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.2 1.7e-05 0.0014 8 38 .] 100 132 .. 93 132 .. 0.80 2 ? 4.0 0.3 6.2 5e+02 8 33 .. 188 215 .. 181 218 .. 0.69 3 ? 5.0 0.1 3.1 2.5e+02 8 34 .. 230 258 .. 222 259 .. 0.82 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.7e-05 ESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++H vt++a sp+++ ++ s+s+D+ + +Wd tr|B4DP38|B4DP38_HUMAN 100 SAHaAQVTCVAASPHKDSVFlSCSEDNRILLWD 132 689777*****77777775339**********9 PP == domain 2 score: 4.0 bits; conditional E-value: 6.2 ESS.SSEEEEEEETTSSEEEEE.ETTSE CS WD40 8 tGH.ssvtslafspdgawlasG.sdDgt 33 H ++vt+l fsp++ ++++ s+D++ tr|B4DP38|B4DP38_HUMAN 188 AVHsQCVTGLVFSPHSVPFLASlSEDCS 215 4696669***999998766656566666 PP == domain 3 score: 5.0 bits; conditional E-value: 3.1 ESS.SSEEEEEEETTSSEEEEE.ETTSEE CS WD40 8 tGH.ssvtslafspdgawlasG.sdDgtv 34 +H ++v++ +sp ++ l++ ++D+ v tr|B4DP38|B4DP38_HUMAN 230 QAHrDFVRDATWSPLNHSLLTTvGWDHQV 258 489888****99999999986669**987 PP >> tr|H3BU82|H3BU82_HUMAN Aladin (Fragment) OS=Homo sapiens GN=AAAS PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.1 7.5e-06 0.00061 6 38 .] 80 113 .. 75 113 .. 0.88 2 ? 4.2 0.0 5.6 4.6e+02 12 28 .. 129 145 .. 122 155 .. 0.78 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 7.5e-06 EEESSSSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 6 tltGHssvtslafspdgawlasGs.dDgtvriWd 38 + GH++vtsla+ p+g l+s+s D +r+Wd tr|H3BU82|H3BU82_HUMAN 80 SHPGHTPVTSLAWAPSGGRLLSASpVDAAIRVWD 113 3359*99****************999*******9 PP == domain 2 score: 4.2 bits; conditional E-value: 5.6 SEEEEEEETTSSEEEEE CS WD40 12 svtslafspdgawlasG 28 +vt l +spdg+ +++ tr|H3BU82|H3BU82_HUMAN 129 GVTNLLWSPDGSKILAT 145 59*********998754 PP >> sp|O14576|DC1I1_HUMAN Cytoplasmic dynein 1 intermediate chain 1 OS=Homo sapiens GN=DYNC1I1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 5.6 4.5e+02 7 38 .] 280 325 .. 275 325 .. 0.67 2 ? 9.4 0.0 0.12 9.8 7 38 .] 335 369 .. 329 369 .. 0.81 3 ! 13.4 0.3 0.0069 0.56 6 37 .. 479 517 .. 476 518 .. 0.78 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 5.6 EESS..SS..EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 7 ltGH..ss..vtslafspdgawlasGsd..........DgtvriWd 38 ++ H ++ vt++++s + l+ +s+ Dg +W+ sp|O14576|DC1I1_HUMAN 280 YDEHwsKHrvVTCMDWSLQYPELMVASYnnnedaphepDGVALVWN 325 66787444878***77666666766665455667777777777776 PP == domain 2 score: 9.4 bits; conditional E-value: 0.12 EESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 7 ltGH..ssvtslafspdgawlasGs.dDgtvriWd 38 + H ssv s++f + ++ l+ G+ + g + +Wd sp|O14576|DC1I1_HUMAN 335 YVFHcqSSVMSVCFARFHPNLVVGGtYSGQIVLWD 369 55676577*****99999999988548*******9 PP == domain 3 score: 13.4 bits; conditional E-value: 0.0069 EEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 +++GH ++vt++ + ++ ++ ++s D tv++W sp|O14576|DC1I1_HUMAN 479 VFEGHqGPVTGINchmavgpIDFSHLFV-TSSFDWTVKLW 517 689**88899997777888766666666.5666******* PP >> sp|Q8NA75|DC4L2_HUMAN DDB1- and CUL4-associated factor 4-like protein 2 OS=Homo sapiens GN=DCAF4L2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.3 4.2e-05 0.0034 9 38 .] 268 298 .. 262 298 .. 0.90 2 ? 8.1 0.0 0.32 26 2 38 .] 303 342 .. 302 342 .. 0.74 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 4.2e-05 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 H s vtsl+ +dg++l+s+++ gt+++Wd sp|Q8NA75|DC4L2_HUMAN 268 SHdSAVTSLQILQDGQFLVSSDMTGTIKLWD 298 69777**************9999*******9 PP == domain 2 score: 8.1 bits; conditional E-value: 0.32 EEEEEEESS..SS......EE...EEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH..ss......vt...slafspdgawlasGsdDgtvriWd 38 +c++ ++GH +s v+ ++ +a+ + D+ riW+ sp|Q8NA75|DC4L2_HUMAN 303 KCVTQYEGHvnNSaylpvhVNeeeGV--------VAAVGQDCYTRIWS 342 7999*****84447877444245566........888899*******5 PP >> sp|Q9H808|TLE6_HUMAN Transducin-like enhancer protein 6 OS=Homo sapiens GN=TLE6 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.1 0.05 4.1 4 31 .. 493 522 .. 490 528 .. 0.77 2 ? 9.1 0.0 0.15 12 11 29 .. 543 561 .. 533 568 .. 0.86 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.05 EEEEESS.SS.EEEEEEETTSSEEEEEETT CS WD40 4 lrtltGH.ss.vtslafspdgawlasGsdD 31 +r+ G+ +s + s++fsp g+w as ++D sp|Q9H808|TLE6_HUMAN 493 QRHMVGQkDSvILSVKFSPFGQWWASVGMD 522 788899955567***********7764445 PP == domain 2 score: 9.1 bits; conditional E-value: 0.15 SSEEEEEEETTSSEEEEEE CS WD40 11 ssvtslafspdgawlasGs 29 s+vt++++s++++++++Gs sp|Q9H808|TLE6_HUMAN 543 SPVTCCDVSSNNRLVVTGS 561 57****************8 PP >> tr|C9JDR5|C9JDR5_HUMAN WD repeat-containing protein 53 (Fragment) OS=Homo sapiens GN=WDR53 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.1 0.8 65 8 30 .. 7 29 .. 3 41 .. 0.72 2 ? 11.2 0.1 0.033 2.7 9 36 .. 90 120 .. 40 122 .. 0.85 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.8 ESS.SSEEEEEEETTSSEEEEEET CS WD40 8 tGH.ssvtslafspdgawlasGsd 30 GH s+v +l s++g + asG + tr|C9JDR5|C9JDR5_HUMAN 7 GGHsSPVLCLNASKEGLL-ASGAE 29 49*888****88888877.78853 PP == domain 2 score: 11.2 bits; conditional E-value: 0.033 SS.SS..EEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GH.ss..vtslafspdgawlasGsdDgtvri 36 H + +++l+ ++ ++las++d g ++i tr|C9JDR5|C9JDR5_HUMAN 90 FHvNEeeINCLSLNQTENLLASADDSGAIKI 120 3454467999999999999999998999988 PP >> tr|F8VZ44|F8VZ44_HUMAN Aladin OS=Homo sapiens GN=AAAS PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.1 9.5 7.7e+02 15 38 .] 29 55 .. 18 55 .. 0.82 2 ! 22.4 0.1 9.4e-06 0.00076 6 38 .] 116 149 .. 111 149 .. 0.88 3 ? 3.9 0.0 6.9 5.6e+02 12 28 .. 165 181 .. 158 191 .. 0.78 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 9.5 EEE...EETTSSEEEEEETTSEEEEEE CS WD40 15 sla...fspdgawlasGsdDgtvriWd 38 +l+ ++p+ + +a + D +vr+++ tr|F8VZ44|F8VZ44_HUMAN 29 CLRvfaWHPHTNKFAVALLDDSVRVYN 55 444666*******999977******97 PP == domain 2 score: 22.4 bits; conditional E-value: 9.4e-06 EEESSSSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 6 tltGHssvtslafspdgawlasGs.dDgtvriWd 38 + GH++vtsla+ p+g l+s+s D +r+Wd tr|F8VZ44|F8VZ44_HUMAN 116 SHPGHTPVTSLAWAPSGGRLLSASpVDAAIRVWD 149 3359*99****************999*******9 PP == domain 3 score: 3.9 bits; conditional E-value: 6.9 SEEEEEEETTSSEEEEE CS WD40 12 svtslafspdgawlasG 28 +vt l +spdg+ +++ tr|F8VZ44|F8VZ44_HUMAN 165 GVTNLLWSPDGSKILAT 181 59*********998754 PP >> tr|H0Y9P0|H0Y9P0_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 (Fragment) OS=Homo sapiens GN=GNB2L1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.2 4.3e-06 0.00035 10 38 .] 7 34 .. 1 34 [. 0.84 2 ? 6.0 0.1 1.4 1.2e+02 13 25 .. 60 75 .. 46 81 .. 0.75 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 4.3e-06 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 + +++l+fsp+ wl++++ ++++iWd tr|H0Y9P0|H0Y9P0_HUMAN 7 G-DiINALCFSPNRYWLCAAT-GPSIKIWD 34 4.447************9888.*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.4 EEEEEEETTSSE...E CS WD40 13 vtslafspdgaw...l 25 tsla+s dg+ + tr|H0Y9P0|H0Y9P0_HUMAN 60 CTSLAWSADGQVsgsV 75 59*********94444 PP >> tr|H0Y4Q6|H0Y4Q6_HUMAN General transcription factor 3C polypeptide 2 (Fragment) OS=Homo sapiens GN=GTF3C2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 3.8 3.1e+02 15 38 .] 68 93 .. 44 93 .. 0.76 2 ! 16.9 0.1 0.00054 0.044 6 38 .] 117 151 .. 106 151 .. 0.74 3 ? 5.5 0.0 2.1 1.7e+02 8 36 .. 331 372 .. 326 373 .. 0.66 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 3.8 EEEEETTSSE..EEEEETTSEEEEEE CS WD40 15 slafspdgaw..lasGsdDgtvriWd 38 sla+ p + la+G ++g v +W+ tr|H0Y4Q6|H0Y4Q6_HUMAN 68 SLAWMPTRPHqhLAAGYYNGMVVFWN 93 555555555576899*99*******8 PP == domain 2 score: 16.9 bits; conditional E-value: 0.00054 EEESS.SSEEEEEEETTSSE.EE.EEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw.la.sGsdDgtvriWd 38 + +H + v+ l++++ ++ l+ +Gs D+++++Wd tr|H0Y4Q6|H0Y4Q6_HUMAN 117 CFLAHdQAVRTLQWCKANSHfLVsAGS-DRKIKFWD 151 566897779999755555555552567.*******9 PP == domain 3 score: 5.5 bits; conditional E-value: 2.1 ESSSS..........EEEEEEETTSSE...EEEEETTSEEEE CS WD40 8 tGHss..........vtslafspdgaw...lasGsdDgtvri 36 +GHs ++ ++fsp+ + l+sG+ g vri tr|H0Y4Q6|H0Y4Q6_HUMAN 331 EGHSQlcldrlqleaIHKVRFSPNLDSygwLVSGGQSGLVRI 372 577443444444444555667777666666*****9999998 PP >> sp|Q969U6-2|FBXW5_HUMAN Isoform 2 of F-box/WD repeat-containing protein 5 OS=Homo sapiens GN=FBXW5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.9 0.4 1.8e-07 1.5e-05 4 38 .] 85 120 .. 82 120 .. 0.91 Alignments for each domain: == domain 1 score: 27.9 bits; conditional E-value: 1.8e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++tl+ H + v +l+fs++g +as+s+D+tv+iW+ sp|Q969U6-2|FBXW5_HUMAN 85 VQTLREHtDQVLHLSFSHSGYQFASCSKDCTVKIWS 120 789****666*************************5 PP >> tr|U3KQK3|U3KQK3_HUMAN WD repeat-containing protein 18 (Fragment) OS=Homo sapiens GN=WDR18 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.0 0.5 7.8e-08 6.3e-06 13 38 .] 1 26 [. 1 26 [. 0.98 Alignments for each domain: == domain 1 score: 29.0 bits; conditional E-value: 7.8e-08 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 vt+l++s dg+ l+sGs D tvr+Wd tr|U3KQK3|U3KQK3_HUMAN 1 VTCLSVSTDGSVLLSGSHDETVRLWD 26 8***************99*******9 PP >> sp|Q13409-6|DC1I2_HUMAN Isoform 2F of Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens GN=DYNC1I2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.1 8.5 6.9e+02 10 38 .] 253 291 .. 246 291 .. 0.75 2 ? 3.9 0.0 7 5.7e+02 8 38 .] 302 335 .. 295 335 .. 0.71 3 ? 4.0 0.2 6.2 5.1e+02 9 37 .. 353 384 .. 344 385 .. 0.70 4 ! 13.1 0.6 0.0084 0.68 7 37 .. 446 483 .. 442 484 .. 0.77 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.5 SSS.EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsd..........DgtvriWd 38 H v++l++s+ + l+ +s+ Dg +W+ sp|Q13409-6|DC1I2_HUMAN 253 H-RvVSCLDWSSQYPELLVASYnnnedaphepDGVALVWN 291 4.4479**99999888877775566677888888888886 PP == domain 2 score: 3.9 bits; conditional E-value: 7 ESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGs.dDgtvriWd 38 H s v s f + ++ l+ G+ + g + +Wd sp|Q13409-6|DC1I2_HUMAN 302 VFHcqSAVMSATFAKFHPNLVVGGtYSGQIVLWD 335 45653448777777777778878538*******9 PP == domain 3 score: 4.0 bits; conditional E-value: 6.2 SS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriW 37 +H +v+++ ++ +++++ ++ Dg++ W sp|Q13409-6|DC1I2_HUMAN 353 AHtHPVYCVNvvgTQNAHNLISIST-DGKICSW 384 5633699998875555555565667.****999 PP == domain 4 score: 13.1 bits; conditional E-value: 0.0084 EESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 ++GH +++t++ ++ ++ +++ +s D tv++W sp|Q13409-6|DC1I2_HUMAN 446 FEGHqGPITGIHchaavgaVDFSHLFVT-SSFDWTVKLW 483 88**877776666669988788888875.555******* PP >> sp|Q13409-3|DC1I2_HUMAN Isoform 2C of Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens GN=DYNC1I2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.1 8.5 6.9e+02 10 38 .] 253 291 .. 246 291 .. 0.75 2 ? 3.8 0.0 7 5.7e+02 8 38 .] 302 335 .. 295 335 .. 0.71 3 ? 4.0 0.2 6.3 5.1e+02 9 37 .. 353 384 .. 344 385 .. 0.70 4 ! 13.1 0.6 0.0084 0.68 7 37 .. 446 483 .. 442 484 .. 0.77 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.5 SSS.EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsd..........DgtvriWd 38 H v++l++s+ + l+ +s+ Dg +W+ sp|Q13409-3|DC1I2_HUMAN 253 H-RvVSCLDWSSQYPELLVASYnnnedaphepDGVALVWN 291 4.4479**99999888877775566677888888888886 PP == domain 2 score: 3.8 bits; conditional E-value: 7 ESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGs.dDgtvriWd 38 H s v s f + ++ l+ G+ + g + +Wd sp|Q13409-3|DC1I2_HUMAN 302 VFHcqSAVMSATFAKFHPNLVVGGtYSGQIVLWD 335 45653448777777777778878538*******9 PP == domain 3 score: 4.0 bits; conditional E-value: 6.3 SS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriW 37 +H +v+++ ++ +++++ ++ Dg++ W sp|Q13409-3|DC1I2_HUMAN 353 AHtHPVYCVNvvgTQNAHNLISIST-DGKICSW 384 5633699998875555555565667.****999 PP == domain 4 score: 13.1 bits; conditional E-value: 0.0084 EESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 ++GH +++t++ ++ ++ +++ +s D tv++W sp|Q13409-3|DC1I2_HUMAN 446 FEGHqGPITGIHchaavgaVDFSHLFVT-SSFDWTVKLW 483 88**877776666669988788888875.555******* PP >> tr|B7ZA04|B7ZA04_HUMAN Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens GN=DYNC1I2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 8.8 7.2e+02 10 38 .] 271 309 .. 264 309 .. 0.75 2 ? 3.8 0.0 7.3 5.9e+02 8 38 .] 320 353 .. 313 353 .. 0.71 3 ? 4.0 0.2 6.5 5.2e+02 9 37 .. 371 402 .. 362 403 .. 0.70 4 ! 13.0 0.6 0.0087 0.71 7 37 .. 464 501 .. 460 502 .. 0.77 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 8.8 SSS.EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsd..........DgtvriWd 38 H v++l++s+ + l+ +s+ Dg +W+ tr|B7ZA04|B7ZA04_HUMAN 271 H-RvVSCLDWSSQYPELLVASYnnnedaphepDGVALVWN 309 4.4479**99999888877775566677888888888886 PP == domain 2 score: 3.8 bits; conditional E-value: 7.3 ESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGs.dDgtvriWd 38 H s v s f + ++ l+ G+ + g + +Wd tr|B7ZA04|B7ZA04_HUMAN 320 VFHcqSAVMSATFAKFHPNLVVGGtYSGQIVLWD 353 45653448777777777778878538*******9 PP == domain 3 score: 4.0 bits; conditional E-value: 6.5 SS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriW 37 +H +v+++ ++ +++++ ++ Dg++ W tr|B7ZA04|B7ZA04_HUMAN 371 AHtHPVYCVNvvgTQNAHNLISIST-DGKICSW 402 5633699998875555555565667.****999 PP == domain 4 score: 13.0 bits; conditional E-value: 0.0087 EESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 ++GH +++t++ ++ ++ +++ +s D tv++W tr|B7ZA04|B7ZA04_HUMAN 464 FEGHqGPITGIHchaavgaVDFSHLFVT-SSFDWTVKLW 501 88**877776666669988788888875.555******* PP >> sp|Q13409-2|DC1I2_HUMAN Isoform 2B of Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens GN=DYNC1I2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 8.9 7.2e+02 10 38 .] 273 311 .. 266 311 .. 0.75 2 ? 3.8 0.0 7.3 5.9e+02 8 38 .] 322 355 .. 315 355 .. 0.71 3 ? 4.0 0.2 6.5 5.3e+02 9 37 .. 373 404 .. 364 405 .. 0.70 4 ! 13.0 0.6 0.0088 0.71 7 37 .. 466 503 .. 462 504 .. 0.77 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 8.9 SSS.EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsd..........DgtvriWd 38 H v++l++s+ + l+ +s+ Dg +W+ sp|Q13409-2|DC1I2_HUMAN 273 H-RvVSCLDWSSQYPELLVASYnnnedaphepDGVALVWN 311 4.4479**99999888877775566677888888888886 PP == domain 2 score: 3.8 bits; conditional E-value: 7.3 ESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGs.dDgtvriWd 38 H s v s f + ++ l+ G+ + g + +Wd sp|Q13409-2|DC1I2_HUMAN 322 VFHcqSAVMSATFAKFHPNLVVGGtYSGQIVLWD 355 45653448777777777778878538*******9 PP == domain 3 score: 4.0 bits; conditional E-value: 6.5 SS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriW 37 +H +v+++ ++ +++++ ++ Dg++ W sp|Q13409-2|DC1I2_HUMAN 373 AHtHPVYCVNvvgTQNAHNLISIST-DGKICSW 404 5633699998875555555565667.****999 PP == domain 4 score: 13.0 bits; conditional E-value: 0.0088 EESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 ++GH +++t++ ++ ++ +++ +s D tv++W sp|Q13409-2|DC1I2_HUMAN 466 FEGHqGPITGIHchaavgaVDFSHLFVT-SSFDWTVKLW 503 88**877776666669988788888875.555******* PP >> sp|Q13409-5|DC1I2_HUMAN Isoform 2E of Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens GN=DYNC1I2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 9 7.3e+02 10 38 .] 279 317 .. 272 317 .. 0.75 2 ? 3.8 0.0 7.4 6e+02 8 38 .] 328 361 .. 321 361 .. 0.71 3 ? 3.9 0.2 6.6 5.3e+02 9 37 .. 379 410 .. 370 411 .. 0.70 4 ! 13.0 0.6 0.0088 0.72 7 37 .. 472 509 .. 468 510 .. 0.77 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 9 SSS.EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsd..........DgtvriWd 38 H v++l++s+ + l+ +s+ Dg +W+ sp|Q13409-5|DC1I2_HUMAN 279 H-RvVSCLDWSSQYPELLVASYnnnedaphepDGVALVWN 317 4.4479**99999888877775566677888888888886 PP == domain 2 score: 3.8 bits; conditional E-value: 7.4 ESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGs.dDgtvriWd 38 H s v s f + ++ l+ G+ + g + +Wd sp|Q13409-5|DC1I2_HUMAN 328 VFHcqSAVMSATFAKFHPNLVVGGtYSGQIVLWD 361 45653448777777777778878538*******9 PP == domain 3 score: 3.9 bits; conditional E-value: 6.6 SS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriW 37 +H +v+++ ++ +++++ ++ Dg++ W sp|Q13409-5|DC1I2_HUMAN 379 AHtHPVYCVNvvgTQNAHNLISIST-DGKICSW 410 5633699998875555555565667.****999 PP == domain 4 score: 13.0 bits; conditional E-value: 0.0088 EESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 ++GH +++t++ ++ ++ +++ +s D tv++W sp|Q13409-5|DC1I2_HUMAN 472 FEGHqGPITGIHchaavgaVDFSHLFVT-SSFDWTVKLW 509 88**877776666669988788888875.555******* PP >> tr|F8W8S0|F8W8S0_HUMAN Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens GN=DYNC1I2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 9 7.3e+02 10 38 .] 279 317 .. 272 317 .. 0.75 2 ? 3.8 0.0 7.4 6e+02 8 38 .] 328 361 .. 321 361 .. 0.71 3 ? 3.9 0.2 6.6 5.3e+02 9 37 .. 379 410 .. 370 411 .. 0.70 4 ! 13.0 0.6 0.0089 0.72 7 37 .. 472 509 .. 468 510 .. 0.77 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 9 SSS.EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsd..........DgtvriWd 38 H v++l++s+ + l+ +s+ Dg +W+ tr|F8W8S0|F8W8S0_HUMAN 279 H-RvVSCLDWSSQYPELLVASYnnnedaphepDGVALVWN 317 4.4479**99999888877775566677888888888886 PP == domain 2 score: 3.8 bits; conditional E-value: 7.4 ESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGs.dDgtvriWd 38 H s v s f + ++ l+ G+ + g + +Wd tr|F8W8S0|F8W8S0_HUMAN 328 VFHcqSAVMSATFAKFHPNLVVGGtYSGQIVLWD 361 45653448777777777778878538*******9 PP == domain 3 score: 3.9 bits; conditional E-value: 6.6 SS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriW 37 +H +v+++ ++ +++++ ++ Dg++ W tr|F8W8S0|F8W8S0_HUMAN 379 AHtHPVYCVNvvgTQNAHNLISIST-DGKICSW 410 5633699998875555555565667.****999 PP == domain 4 score: 13.0 bits; conditional E-value: 0.0089 EESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 ++GH +++t++ ++ ++ +++ +s D tv++W tr|F8W8S0|F8W8S0_HUMAN 472 FEGHqGPITGIHchaavgaVDFSHLFVT-SSFDWTVKLW 509 88**877776666669988788888875.555******* PP >> sp|Q13409|DC1I2_HUMAN Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens GN=DYNC1I2 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 9 7.3e+02 10 38 .] 279 317 .. 272 317 .. 0.75 2 ? 3.8 0.0 7.4 6e+02 8 38 .] 328 361 .. 321 361 .. 0.71 3 ? 3.9 0.2 6.6 5.3e+02 9 37 .. 379 410 .. 370 411 .. 0.70 4 ! 13.0 0.6 0.0089 0.72 7 37 .. 472 509 .. 468 510 .. 0.77 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 9 SSS.EEEEEEETTSSEEEEEET..........TSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsd..........DgtvriWd 38 H v++l++s+ + l+ +s+ Dg +W+ sp|Q13409|DC1I2_HUMAN 279 H-RvVSCLDWSSQYPELLVASYnnnedaphepDGVALVWN 317 4.4479**99999888877775566677888888888886 PP == domain 2 score: 3.8 bits; conditional E-value: 7.4 ESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 8 tGH..ssvtslafspdgawlasGs.dDgtvriWd 38 H s v s f + ++ l+ G+ + g + +Wd sp|Q13409|DC1I2_HUMAN 328 VFHcqSAVMSATFAKFHPNLVVGGtYSGQIVLWD 361 45653448777777777778878538*******9 PP == domain 3 score: 3.9 bits; conditional E-value: 6.6 SS.SSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvriW 37 +H +v+++ ++ +++++ ++ Dg++ W sp|Q13409|DC1I2_HUMAN 379 AHtHPVYCVNvvgTQNAHNLISIST-DGKICSW 410 5633699998875555555565667.****999 PP == domain 4 score: 13.0 bits; conditional E-value: 0.0089 EESS.SSEEEEE.......EETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtsla.......fspdgawlasGsdDgtvriW 37 ++GH +++t++ ++ ++ +++ +s D tv++W sp|Q13409|DC1I2_HUMAN 472 FEGHqGPITGIHchaavgaVDFSHLFVT-SSFDWTVKLW 509 88**877776666669988788888875.555******* PP >> tr|B1AKQ8|B1AKQ8_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Fragment) OS=Homo sapiens G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 0.0 2.8e-07 2.2e-05 4 38 .] 48 83 .. 45 83 .. 0.94 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 2.8e-07 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 rtl+GH ++++ + d+++l+s+s Dg++ iWd tr|B1AKQ8|B1AKQ8_HUMAN 48 RRTLRGHlAKIYAMHWGTDSRLLVSASQDGKLIIWD 83 689****999*************************9 PP >> tr|K7ERC0|K7ERC0_HUMAN WD repeat-containing protein 16 (Fragment) OS=Homo sapiens GN=WDR16 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.0 3.8e-05 0.0031 7 38 .] 9 41 .. 3 41 .. 0.90 2 ? 5.9 0.0 1.6 1.3e+02 14 35 .. 58 79 .. 48 84 .. 0.84 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 3.8e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l+ H ssv+++++ +++ +++s Dgt+ iWd tr|K7ERC0|K7ERC0_HUMAN 9 LKEHkSSVSCIRVKRNNEECVTASTDGTCIIWD 41 789*888************999999*******9 PP == domain 2 score: 5.9 bits; conditional E-value: 1.6 EEEEEETTSSEEEEEETTSEEE CS WD40 14 tslafspdgawlasGsdDgtvr 35 +++++p+ +++++ D++v tr|K7ERC0|K7ERC0_HUMAN 58 QCVCYHPEEFQIITSGTDRKVE 79 59999999999987777**996 PP >> tr|J3KTF7|J3KTF7_HUMAN CMT1A duplicated region transcript 1 protein OS=Homo sapiens GN=CDRT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.2 0.0025 0.2 24 38 .] 7 21 .. 2 21 .. 0.87 2 ? 12.8 0.1 0.01 0.85 1 37 [. 25 59 .. 25 60 .. 0.89 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 0.0025 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 l+sG++D+ v++Wd tr|J3KTF7|J3KTF7_HUMAN 7 RLVSGGRDCQVKVWD 21 5789**********9 PP == domain 2 score: 12.8 bits; conditional E-value: 0.01 TEEEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssv..tslafspdgawlasGsdDgtvriW 37 g+cl+t++ H +++ t + + ++++s+++ g v++W tr|J3KTF7|J3KTF7_HUMAN 25 GKCLKTFR-HkDPIlaTRI----NDTYIVSSCERGLVKVW 59 79*****9.9666778999....******9999******* PP >> tr|K7EKU5|K7EKU5_HUMAN Echinoderm microtubule-associated protein-like 2 (Fragment) OS=Homo sapiens GN=EML2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.4 0.00029 0.024 2 38 .] 74 121 .. 73 121 .. 0.81 2 ? 5.3 0.2 2.4 1.9e+02 13 38 .] 140 169 .. 127 169 .. 0.69 3 ? 5.6 0.0 2 1.6e+02 18 37 .. 191 210 .. 174 211 .. 0.73 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 0.00029 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 q +r++ GH +++ +la +pd +a+G + ++vriWd tr|K7EKU5|K7EKU5_HUMAN 74 QRQRHYLGHnDDIKCLAIHPDMVTIATGqvaGTtkegkplPPHVRIWD 121 779******666*************99754422457778899999998 PP == domain 2 score: 5.3 bits; conditional E-value: 2.4 EEEEE..EETTSSEEEEE..ETTSEEEEEE CS WD40 13 vtsla..fspdgawlasG..sdDgtvriWd 38 v+++ s g++l++ s D+ + +Wd tr|K7EKU5|K7EKU5_HUMAN 140 VCCVGfsKSNGGNLLCAVdeSNDHMLSVWD 169 5555443566666775445556*******9 PP == domain 3 score: 5.6 bits; conditional E-value: 2 EETTSSE.EEEEETTSEEEEE CS WD40 18 fspdgaw.lasGsdDgtvriW 37 f+p + l++++ + ++++W tr|K7EKU5|K7EKU5_HUMAN 191 FHPTDPTvLITCG-KSHIYFW 210 77888883569**.******* PP >> tr|K7EPH1|K7EPH1_HUMAN WD repeat-containing protein 88 OS=Homo sapiens GN=WDR88 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.9 0.7 1.8e-07 1.5e-05 3 38 .] 94 130 .. 92 130 .. 0.89 Alignments for each domain: == domain 1 score: 27.9 bits; conditional E-value: 1.8e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + ++l+GH v+ + f+ d + l+sGs+D+tv++Wd tr|K7EPH1|K7EPH1_HUMAN 94 PFKILSGHeHAVSTCHFCVDDTKLLSGSYDCTVKLWD 130 56899***555*8888999*****************9 PP >> tr|H0YJK4|H0YJK4_HUMAN Echinoderm microtubule-associated protein-like 1 (Fragment) OS=Homo sapiens GN=EML1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 2.0 6.5e-06 0.00053 2 38 .] 4 51 .. 3 51 .. 0.80 2 ? 7.8 1.8 0.39 31 9 38 .] 64 99 .. 55 99 .. 0.65 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 6.5e-06 EEEEEEESS.SSEEEEEEETTSSEEEEE.....ET.....TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG.....sd.....DgtvriWd 38 q++r++ GH ++v +la++pd +a+G s+ ++vriWd tr|H0YJK4|H0YJK4_HUMAN 4 QLQRHYAGHnDDVKCLAVHPDRITIATGqvagtSKdgkqlPPHVRIWD 51 89*******666*************99765433335777788888887 PP == domain 2 score: 7.8 bits; conditional E-value: 0.39 SSSS..EEEEEEETTSSE..EEEE..ETTSEEEEEE CS WD40 9 GHss..vtslafspdgaw..lasG..sdDgtvriWd 38 G ++ vt++afs+++ l++ s D+ + +Wd tr|H0YJK4|H0YJK4_HUMAN 64 GFFDraVTCIAFSKSNGGtnLCAVddSNDHVLSVWD 99 4433579***955555555586654445*******9 PP >> tr|J3QLS4|J3QLS4_HUMAN CMT1A duplicated region transcript 1 protein OS=Homo sapiens GN=CDRT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.2 0.003 0.24 24 38 .] 7 21 .. 2 21 .. 0.87 2 ? 12.4 0.1 0.014 1.1 1 37 [. 25 59 .. 25 60 .. 0.89 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 0.003 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 l+sG++D+ v++Wd tr|J3QLS4|J3QLS4_HUMAN 7 RLVSGGRDCQVKVWD 21 5789**********9 PP == domain 2 score: 12.4 bits; conditional E-value: 0.014 TEEEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssv..tslafspdgawlasGsdDgtvriW 37 g+cl+t++ H +++ t + + ++++s+++ g v++W tr|J3QLS4|J3QLS4_HUMAN 25 GKCLKTFR-HkDPIlaTRI----NDTYIVSSCERGLVKVW 59 79*****9.9666778999....******9999******* PP >> tr|B0QZ36|B0QZ36_HUMAN mRNA export factor (Fragment) OS=Homo sapiens GN=RAE1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.8 2.9 2.4e+02 21 37 .. 53 69 .. 25 70 .. 0.71 2 ! 22.9 0.2 6.5e-06 0.00053 10 38 .] 85 114 .. 77 114 .. 0.91 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 2.9 TSSEEEEEETTSEEEEE CS WD40 21 dgawlasGsdDgtvriW 37 g++l++Gs+ + vr W tr|B0QZ36|B0QZ36_HUMAN 53 PGNFLIAGSWANDVRCW 69 3566999***9999999 PP == domain 2 score: 22.9 bits; conditional E-value: 6.5e-06 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H ++v ++++s+dg+ ++++s D+t ++Wd tr|B0QZ36|B0QZ36_HUMAN 85 HtGPVLDVCWSDDGSKVFTASCDKTAKMWD 114 7667*************99988*******9 PP >> sp|Q15334|L2GL1_HUMAN Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens GN=LLGL1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 1.4 1.9 1.5e+02 5 37 .. 232 264 .. 227 265 .. 0.81 2 ! 13.4 0.0 0.0069 0.56 16 38 .] 447 461 .. 422 461 .. 0.83 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 1.9 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriW 37 +++ G + sl++ +d++ ++s++ Dg+ +W sp|Q15334|L2GL1_HUMAN 232 HIFLGNQQLESLCWGRDSSTVVSSHSDGSYAVW 264 4467887799**************88**97777 PP == domain 2 score: 13.4 bits; conditional E-value: 0.0069 EEEETTSSEEEEEETTSEEEEEE CS WD40 16 lafspdgawlasGsdDgtvriWd 38 l l++G++Dgtvr+Wd sp|Q15334|L2GL1_HUMAN 447 L--------LLTGHEDGTVRFWD 461 2........679**********9 PP >> sp|Q9BTV6|DPH7_HUMAN Diphthamide biosynthesis protein 7 OS=Homo sapiens GN=DPH7 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.1 1.1 86 5 38 .] 189 224 .. 185 224 .. 0.66 2 ! 13.9 0.1 0.0045 0.37 8 38 .] 236 268 .. 229 268 .. 0.81 3 ? 4.3 0.0 4.9 4e+02 23 37 .. 432 447 .. 405 448 .. 0.84 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 1.1 EEEESS.SS..EEEEEEETTSSE.....EEEEETTSEEEEEE CS WD40 5 rtltGH.ss..vtslafspdgaw.....lasGsdDgtvriWd 38 ++ +H + + ++ ++ + sG+dDg +r Wd sp|Q9BTV6|DPH7_HUMAN 189 ASWQAHqFEawIAAF------NYwhpeiVYSGGDDGLLRGWD 224 556666422456666......4446664679********998 PP == domain 2 score: 13.9 bits; conditional E-value: 0.0045 ESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + H +v+s++ sp+ la+Gs+D ++ +Wd sp|Q9BTV6|DPH7_HUMAN 236 KRHtMGVCSIQSSPHREHiLATGSYDEHILLWD 268 4575569****99999994479**********9 PP == domain 3 score: 4.3 bits; conditional E-value: 4.9 SEEEEEE.TTSEEEEE CS WD40 23 awlasGs.dDgtvriW 37 ++la++s +D+ +++W sp|Q9BTV6|DPH7_HUMAN 432 SLLATCSfYDHALHLW 447 339999768******* PP >> tr|J3KSR7|J3KSR7_HUMAN U3 small nucleolar RNA-associated protein 18 homolog (Fragment) OS=Homo sapiens GN=UTP18 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 0.2 0.006 0.49 17 38 .] 96 120 .. 40 120 .. 0.76 2 ? 4.3 0.0 5 4e+02 15 28 .. 140 153 .. 124 161 .. 0.82 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 0.006 E...EETTSSEEEEEETTSEEEEEE CS WD40 17 a...fspdgawlasGsdDgtvriWd 38 a fs+d++ + ++s Dg v++Wd tr|J3KSR7|J3KSR7_HUMAN 96 AastFSSDSKKVYASSGDGEVYVWD 120 25569999999976666*******9 PP == domain 2 score: 4.3 bits; conditional E-value: 5 EEEEETTSSEEEEE CS WD40 15 slafspdgawlasG 28 s+a+s++g+++a+G tr|J3KSR7|J3KSR7_HUMAN 140 SIATSRNGQYVACG 153 678********987 PP >> sp|P61962|DCAF7_HUMAN DDB1- and CUL4-associated factor 7 OS=Homo sapiens GN=DCAF7 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.2 6.4 5.2e+02 13 37 .. 123 148 .. 109 148 .. 0.83 2 ? 10.3 0.0 0.063 5.1 6 38 .] 169 205 .. 161 205 .. 0.79 3 ! 15.0 1.0 0.0021 0.17 4 38 .] 259 295 .. 256 295 .. 0.84 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 6.4 EEEEEEETTSSEEE.EEETTSEEEEE CS WD40 13 vtslafspdgawla.sGsdDgtvriW 37 ts++++ ++l+ ++s D t+ iW sp|P61962|DCAF7_HUMAN 123 LTSFDWNEVDPYLLgTSSIDTTCTIW 148 7999999999999966789******* PP == domain 2 score: 10.3 bits; conditional E-value: 0.063 EEESS.SSEEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw...lasGsdDgtvriWd 38 l +H + v+++afs+ g +as + Dg+vr++d sp|P61962|DCAF7_HUMAN 169 QLIAHdKEVYDIAFSRAGGGrdmFASVGADGSVRMFD 205 36799888****88877777997666566*****998 PP == domain 3 score: 15.0 bits; conditional E-value: 0.0021 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 + l H +v+++a+ p+++ ++ ++ dD+ iWd sp|P61962|DCAF7_HUMAN 259 VARLNNHrACVNGIAWAPHSSCHIcTAADDHQALIWD 295 5667789888************7636689*******9 PP >> sp|Q96DN5-3|TBC31_HUMAN Isoform 3 of TBC1 domain family member 31 OS=Homo sapiens GN=TBC1D31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.0 4.1 3.4e+02 15 38 .] 47 70 .. 33 70 .. 0.87 2 ? 10.5 0.2 0.055 4.5 8 38 .] 123 153 .. 115 153 .. 0.87 3 ? 5.5 0.0 2 1.7e+02 18 37 .. 222 241 .. 211 242 .. 0.88 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 4.1 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +af+ g+ l++G+ g+++++d sp|Q96DN5-3|TBC31_HUMAN 47 NVAFDGTGDCLIAGDHQGNIYVFD 70 588***********88*****998 PP == domain 2 score: 10.5 bits; conditional E-value: 0.055 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH ssv s++++ +g++ ++ s t +Wd sp|Q96DN5-3|TBC31_HUMAN 123 RGHeSSVFSISVHASGKYAITTS-SDTAQLWD 153 8**999************99989.88888887 PP == domain 3 score: 5.5 bits; conditional E-value: 2 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 + +dg+ la+G++ +++++W sp|Q96DN5-3|TBC31_HUMAN 222 VTRDGRILAAGGKSNHLHLW 241 5889**************** PP >> sp|Q9BZH6|WDR11_HUMAN WD repeat-containing protein 11 OS=Homo sapiens GN=WDR11 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 1.6 1.3e+02 2 38 .] 52 99 .. 51 99 .. 0.71 2 ? 9.8 0.2 0.09 7.3 9 38 .] 708 736 .. 701 736 .. 0.81 3 ? 4.9 0.3 3.2 2.6e+02 13 36 .. 798 820 .. 784 820 .. 0.81 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 1.6 EEEEEEESS.SSEEEEE.....EETTSSE..........EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.....fspdgaw..........lasGsdDgtvriWd 38 q+l++l+ H +v ++ + las++ +g++ +Wd sp|Q9BZH6|WDR11_HUMAN 52 QTLQVLEKHkADVVKVKwarenY-----HhnigspyclrLASADVNGKIIVWD 99 67888999977788997444440.....35555555555999999*******9 PP == domain 2 score: 9.8 bits; conditional E-value: 0.09 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 G +s+t++a+ d l G++Dg++ +Wd sp|Q9BZH6|WDR11_HUMAN 708 GSmGSITCIAWKGDTLVL--GDMDGNLNFWD 736 56567****777776666..*99*******9 PP == domain 3 score: 4.9 bits; conditional E-value: 3.2 EEEEEEETTSSEEEEEETTSEEEE CS WD40 13 vtslafspdgawlasGsdDgtvri 36 + +++++ + + +++ sdDg +r+ sp|Q9BZH6|WDR11_HUMAN 798 ILDVDWCTSDKVILA-SDDGCIRV 820 889999999999995.66****97 PP >> sp|Q9NRG9|AAAS_HUMAN Aladin OS=Homo sapiens GN=AAAS PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.1 1.3e-05 0.0011 6 38 .] 240 273 .. 235 273 .. 0.88 2 ? 3.4 0.0 9.5 7.7e+02 12 28 .. 289 305 .. 282 315 .. 0.78 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.3e-05 EEESSSSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 6 tltGHssvtslafspdgawlasGs.dDgtvriWd 38 + GH++vtsla+ p+g l+s+s D +r+Wd sp|Q9NRG9|AAAS_HUMAN 240 SHPGHTPVTSLAWAPSGGRLLSASpVDAAIRVWD 273 3359*99****************999*******9 PP == domain 2 score: 3.4 bits; conditional E-value: 9.5 SEEEEEEETTSSEEEEE CS WD40 12 svtslafspdgawlasG 28 +vt l +spdg+ +++ sp|Q9NRG9|AAAS_HUMAN 289 GVTNLLWSPDGSKILAT 305 59*********998754 PP >> tr|Q5T321|Q5T321_HUMAN Neurobeachin OS=Homo sapiens GN=NBEA PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.1 7.2 5.8e+02 14 37 .. 2678 2702 .. 2664 2703 .. 0.75 2 ? 10.2 0.3 0.071 5.7 4 37 .. 2710 2748 .. 2707 2748 .. 0.78 3 ? 7.6 0.0 0.47 38 17 37 .. 2866 2886 .. 2853 2887 .. 0.89 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.2 EEEEEETTSSEEE.EEETTSEEEEE CS WD40 14 tslafspdgawla.sGsdDgtvriW 37 +++ + d+++++ +G +D++ r++ tr|Q5T321|Q5T321_HUMAN 2678 HCFVVTADNRYILiCGFWDKSFRVY 2702 35556779999653888******98 PP == domain 2 score: 10.2 bits; conditional E-value: 0.071 EEEEESSSS.EEEEE....EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtsla....fspdgawlasGsdDgtvriW 37 +++ GH + vt+la + +++sGs+D t+ +W tr|Q5T321|Q5T321_HUMAN 2710 TQIVFGHWDvVTCLArsesYIGGDCYIVSGSRDATLLLW 2748 555559*3358***9888877777779************ PP == domain 3 score: 7.6 bits; conditional E-value: 0.47 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 s+dg+ l++G+d+g v +W tr|Q5T321|Q5T321_HUMAN 2866 LLSSDGQNLVTGGDNGVVEVW 2886 5799***************** PP >> tr|F5H8E6|F5H8E6_HUMAN WD repeat-containing protein 20 OS=Homo sapiens GN=WDR20 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.4 1.3e-05 0.0011 14 38 .] 9 33 .. 2 33 .. 0.91 2 ? 3.5 0.0 8.9 7.2e+02 8 24 .. 44 61 .. 37 77 .. 0.71 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.3e-05 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++++spdg+++++G++D v +W+ tr|F5H8E6|F5H8E6_HUMAN 9 LCVCWSPDGKYIVTGGEDDLVTVWS 33 6***********************5 PP == domain 2 score: 3.5 bits; conditional E-value: 8.9 ESS.SSEEEEEEETTSSE CS WD40 8 tGH.ssvtslafspdgaw 24 GH s+v+ +af+p+ + tr|F5H8E6|F5H8E6_HUMAN 44 HGHkSWVSVVAFDPYTTS 61 477666999999999775 PP >> tr|B3KRG7|B3KRG7_HUMAN DENN domain-containing protein 3 OS=Homo sapiens GN=DENND3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.1 0.00036 0.029 2 38 .] 27 67 .. 26 67 .. 0.78 2 ? 6.1 0.0 1.4 1.1e+02 5 38 .] 211 246 .. 207 246 .. 0.77 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 0.00036 EEEEEEESS.SSEEEEE...EETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgaw....lasGsdDgtvriWd 38 +c + lt+H ssvt+l + + s+s+Dg v +W+ tr|B3KRG7|B3KRG7_HUMAN 27 SCNKQLTAHcSSVTDLIvqdG----QEapsnVYSCSMDGMVLVWN 67 68999****999****54331....224666789**********8 PP == domain 2 score: 6.1 bits; conditional E-value: 1.4 EEEESS.SSEEEEEEETTSSEEEEEE..TTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGs..dDgtvriWd 38 ++l +H + v+ l s + ++++sGs + g+v iW+ tr|B3KRG7|B3KRG7_HUMAN 211 KELVAHmDTVRTL-CSAEDRYVLSGSgrEEGKVAIWK 246 5677998889999.666667777886557******95 PP >> tr|D6RAF7|D6RAF7_HUMAN Intraflagellar transport protein 122 homolog OS=Homo sapiens GN=IFT122 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.013 1 10 34 .. 13 45 .. 4 47 .. 0.78 2 ! 14.2 0.0 0.0037 0.3 2 24 .. 44 67 .. 43 79 .. 0.81 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 SSSEEEEEEETTSSE..EEEEET.......TSEE CS WD40 10 Hssvtslafspdgaw..lasGsd.......Dgtv 34 H +++++af pdg+ la+Gs+ Dgt+ tr|D6RAF7|D6RAF7_HUMAN 13 H-CINDIAFKPDGTQliLAAGSRllvydtsDGTL 45 7.7************5446998666666778876 PP == domain 2 score: 14.2 bits; conditional E-value: 0.0037 EEEEEEESSSS.EEEEEEETTSSE CS WD40 2 qclrtltGHss.vtslafspdgaw 24 ++l+ l+GH++ v+++a+ +dg+ tr|D6RAF7|D6RAF7_HUMAN 44 TLLQPLKGHKDtVYCVAYAKDGNE 67 67899****555*****9999986 PP >> sp|Q9NRG9-2|AAAS_HUMAN Isoform 2 of Aladin OS=Homo sapiens GN=AAAS # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.1 1.2e-05 0.00098 6 38 .] 207 240 .. 202 240 .. 0.88 2 ? 3.5 0.0 8.8 7.1e+02 12 28 .. 256 272 .. 249 282 .. 0.78 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 1.2e-05 EEESSSSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 6 tltGHssvtslafspdgawlasGs.dDgtvriWd 38 + GH++vtsla+ p+g l+s+s D +r+Wd sp|Q9NRG9-2|AAAS_HUMAN 207 SHPGHTPVTSLAWAPSGGRLLSASpVDAAIRVWD 240 3359*99****************999*******9 PP == domain 2 score: 3.5 bits; conditional E-value: 8.8 SEEEEEEETTSSEEEEE CS WD40 12 svtslafspdgawlasG 28 +vt l +spdg+ +++ sp|Q9NRG9-2|AAAS_HUMAN 256 GVTNLLWSPDGSKILAT 272 59*********998754 PP >> tr|J3QRV5|J3QRV5_HUMAN Lethal(2) giant larvae protein homolog 2 OS=Homo sapiens GN=LLGL2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.6 1.2 1e+02 17 34 .. 232 254 .. 199 257 .. 0.71 2 ! 14.8 0.0 0.0025 0.2 20 38 .] 433 451 .. 414 451 .. 0.89 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 1.2 E.....EETTSSEEEEEETTSEE CS WD40 17 a.....fspdgawlasGsdDgtv 34 + +++dg++l+s++ Dg+ tr|J3QRV5|J3QRV5_HUMAN 232 QleniwWQRDGRLLVSCHSDGSY 254 145555***********88*985 PP == domain 2 score: 14.8 bits; conditional E-value: 0.0025 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 p ++l++G++Dgtvr+Wd tr|J3QRV5|J3QRV5_HUMAN 433 PQRDLLLTGHEDGTVRFWD 451 6667899***********9 PP >> sp|Q6P1M3|L2GL2_HUMAN Lethal(2) giant larvae protein homolog 2 OS=Homo sapiens GN=LLGL2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.6 1.2 1e+02 17 34 .. 232 254 .. 199 257 .. 0.71 2 ! 14.8 0.0 0.0025 0.2 20 38 .] 433 451 .. 414 451 .. 0.89 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 1.2 E.....EETTSSEEEEEETTSEE CS WD40 17 a.....fspdgawlasGsdDgtv 34 + +++dg++l+s++ Dg+ sp|Q6P1M3|L2GL2_HUMAN 232 QleniwWQRDGRLLVSCHSDGSY 254 145555***********88*985 PP == domain 2 score: 14.8 bits; conditional E-value: 0.0025 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 p ++l++G++Dgtvr+Wd sp|Q6P1M3|L2GL2_HUMAN 433 PQRDLLLTGHEDGTVRFWD 451 6667899***********9 PP >> sp|Q96DN5-2|TBC31_HUMAN Isoform 2 of TBC1 domain family member 31 OS=Homo sapiens GN=TBC1D31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 4.3 3.5e+02 15 38 .] 47 70 .. 33 70 .. 0.87 2 ? 10.5 0.2 0.057 4.6 8 38 .] 123 153 .. 115 153 .. 0.87 3 ? 5.5 0.0 2.1 1.7e+02 18 37 .. 222 241 .. 211 242 .. 0.88 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 4.3 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +af+ g+ l++G+ g+++++d sp|Q96DN5-2|TBC31_HUMAN 47 NVAFDGTGDCLIAGDHQGNIYVFD 70 588***********88*****998 PP == domain 2 score: 10.5 bits; conditional E-value: 0.057 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH ssv s++++ +g++ ++ s t +Wd sp|Q96DN5-2|TBC31_HUMAN 123 RGHeSSVFSISVHASGKYAITTS-SDTAQLWD 153 8**999************99989.88888887 PP == domain 3 score: 5.5 bits; conditional E-value: 2.1 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 + +dg+ la+G++ +++++W sp|Q96DN5-2|TBC31_HUMAN 222 VTRDGRILAAGGKSNHLHLW 241 5889**************** PP >> sp|Q6P1M3-2|L2GL2_HUMAN Isoform A of Lethal(2) giant larvae protein homolog 2 OS=Homo sapiens GN=LLGL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.6 1.2 1e+02 17 34 .. 232 254 .. 199 257 .. 0.71 2 ! 14.8 0.0 0.0025 0.2 20 38 .] 433 451 .. 414 451 .. 0.89 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 1.2 E.....EETTSSEEEEEETTSEE CS WD40 17 a.....fspdgawlasGsdDgtv 34 + +++dg++l+s++ Dg+ sp|Q6P1M3-2|L2GL2_HUMAN 232 QleniwWQRDGRLLVSCHSDGSY 254 145555***********88*985 PP == domain 2 score: 14.8 bits; conditional E-value: 0.0025 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 p ++l++G++Dgtvr+Wd sp|Q6P1M3-2|L2GL2_HUMAN 433 PQRDLLLTGHEDGTVRFWD 451 6667899***********9 PP >> tr|J3KSE6|J3KSE6_HUMAN Cirhin (Fragment) OS=Homo sapiens GN=CIRH1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 0.00028 0.023 12 37 .. 20 45 .. 11 46 .. 0.89 2 ? 7.7 0.0 0.43 35 10 26 .. 61 78 .. 52 79 .] 0.76 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 0.00028 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 +++s+a sp+g+ l+ G++Dg+v+++ tr|J3KSE6|J3KSE6_HUMAN 20 PIWSMAASPSGSQLLVGCEDGSVKLF 45 59**********************97 PP == domain 2 score: 7.7 bits; conditional E-value: 0.43 S.SSEEEEEEETTSSEEE CS WD40 10 H.ssvtslafspdgawla 26 + s + sl+++p+g+ +a tr|J3KSE6|J3KSE6_HUMAN 61 QkSRILSLSWHPSGTHIA 78 534499*********997 PP >> sp|Q8NFP9|NBEA_HUMAN Neurobeachin OS=Homo sapiens GN=NBEA PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.1 7.2 5.8e+02 14 37 .. 2681 2705 .. 2667 2706 .. 0.75 2 ? 10.2 0.3 0.071 5.7 4 37 .. 2713 2751 .. 2710 2751 .. 0.78 3 ? 7.6 0.0 0.47 38 17 37 .. 2869 2889 .. 2857 2890 .. 0.89 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.2 EEEEEETTSSEEE.EEETTSEEEEE CS WD40 14 tslafspdgawla.sGsdDgtvriW 37 +++ + d+++++ +G +D++ r++ sp|Q8NFP9|NBEA_HUMAN 2681 HCFVVTADNRYILiCGFWDKSFRVY 2705 35556779999653888******98 PP == domain 2 score: 10.2 bits; conditional E-value: 0.071 EEEEESSSS.EEEEE....EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtsla....fspdgawlasGsdDgtvriW 37 +++ GH + vt+la + +++sGs+D t+ +W sp|Q8NFP9|NBEA_HUMAN 2713 TQIVFGHWDvVTCLArsesYIGGDCYIVSGSRDATLLLW 2751 555559*3358***9888877777779************ PP == domain 3 score: 7.6 bits; conditional E-value: 0.47 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 s+dg+ l++G+d+g v +W sp|Q8NFP9|NBEA_HUMAN 2869 LLSSDGQNLVTGGDNGVVEVW 2889 5799***************** PP >> tr|F5GXV7|F5GXV7_HUMAN Neurobeachin OS=Homo sapiens GN=NBEA PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.1 7.2 5.8e+02 14 37 .. 2681 2705 .. 2667 2706 .. 0.75 2 ? 10.2 0.3 0.071 5.7 4 37 .. 2713 2751 .. 2710 2751 .. 0.78 3 ? 7.6 0.0 0.47 38 17 37 .. 2869 2889 .. 2857 2890 .. 0.89 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.2 EEEEEETTSSEEE.EEETTSEEEEE CS WD40 14 tslafspdgawla.sGsdDgtvriW 37 +++ + d+++++ +G +D++ r++ tr|F5GXV7|F5GXV7_HUMAN 2681 HCFVVTADNRYILiCGFWDKSFRVY 2705 35556779999653888******98 PP == domain 2 score: 10.2 bits; conditional E-value: 0.071 EEEEESSSS.EEEEE....EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss.vtsla....fspdgawlasGsdDgtvriW 37 +++ GH + vt+la + +++sGs+D t+ +W tr|F5GXV7|F5GXV7_HUMAN 2713 TQIVFGHWDvVTCLArsesYIGGDCYIVSGSRDATLLLW 2751 555559*3358***9888877777779************ PP == domain 3 score: 7.6 bits; conditional E-value: 0.47 EEETTSSEEEEEETTSEEEEE CS WD40 17 afspdgawlasGsdDgtvriW 37 s+dg+ l++G+d+g v +W tr|F5GXV7|F5GXV7_HUMAN 2869 LLSSDGQNLVTGGDNGVVEVW 2889 5799***************** PP >> tr|H0YGB1|H0YGB1_HUMAN Proteasomal ATPase-associated factor 1 (Fragment) OS=Homo sapiens GN=PAAF1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 0.2 3e-06 0.00024 2 38 .] 8 45 .. 7 45 .. 0.87 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 3e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ t++GH +++ + a + g+ ++s+s+Dgt r+Wd tr|H0YGB1|H0YGB1_HUMAN 8 SCVVTFKGHkGGILDTAIVDRGRNVVSASRDGTARLWD 45 6999*****777977777888888899**********9 PP >> tr|C9IZ29|C9IZ29_HUMAN WD repeat-containing protein 49 (Fragment) OS=Homo sapiens GN=WDR49 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.0 1.2e-06 9.4e-05 2 38 .] 74 113 .. 73 113 .. 0.85 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.2e-06 EEEEEEE.SS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtlt.GH.ss.vtslafspdgawlasGsdDgtvriWd 38 q+++ +t H + ++ +a + + + l++Gs Dgtv+iWd tr|C9IZ29|C9IZ29_HUMAN 74 QKIKQFTgCHgNAeISTMALDANETRLLTGSTDGTVKIWD 113 67778874666558*************************9 PP >> sp|Q5VTH9-3|WDR78_HUMAN Isoform 3 of WD repeat-containing protein 78 OS=Homo sapiens GN=WDR78 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 6.7 5.4e+02 12 38 .] 284 311 .. 274 311 .. 0.75 2 ? 4.6 0.3 4.2 3.4e+02 9 37 .. 414 445 .. 407 446 .. 0.64 3 ! 12.9 0.0 0.01 0.81 12 38 .] 461 488 .. 451 488 .. 0.84 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.7 SEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 12 svtslafspdgawl.asGsdDgtvriWd 38 +vt+++fs + l a G +gt+ i++ sp|Q5VTH9-3|WDR78_HUMAN 284 GVTAVDFSIGAPNLlAVGYHNGTIAIYN 311 39999988888886257867****9987 PP == domain 2 score: 4.6 bits; conditional E-value: 4.2 SS.SS.EEEEEEETTSSE.......EEEEETTSEEEEE CS WD40 9 GH.ss.vtslafspdgaw.......lasGsdDgtvriW 37 H ++ v+ + +w ++s+s D v iW sp|Q5VTH9-3|WDR78_HUMAN 414 FHpKGpVYKV------TWnpfchdvFLSCSADWGVIIW 445 3442235555......336666666679999******* PP == domain 3 score: 12.9 bits; conditional E-value: 0.01 S.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriWd 38 s v+++a+sp +++++++ + v iWd sp|Q5VTH9-3|WDR78_HUMAN 461 SvVYDVAWSPKSSYIFAAANENRVEIWD 488 447************98988*******9 PP >> tr|H0Y6L4|H0Y6L4_HUMAN WD repeat-containing protein 64 (Fragment) OS=Homo sapiens GN=WDR64 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 9.3 7.5e+02 13 38 .] 127 154 .. 114 154 .. 0.72 2 ? 8.0 0.0 0.34 27 24 37 .. 263 276 .. 253 277 .. 0.89 3 ? 8.6 0.0 0.23 19 4 37 .. 339 373 .. 336 374 .. 0.69 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 9.3 EEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 13 vtsla..fspdgawlasGsdDgtvriWd 38 v++++ +++a+G+ +g + +W+ tr|H0Y6L4|H0Y6L4_HUMAN 127 VNCIDllQVEGYNLIAAGTLNGVIILWN 154 56663322222355899999*******8 PP == domain 2 score: 8.0 bits; conditional E-value: 0.34 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 l+++++Dg++r+W tr|H0Y6L4|H0Y6L4_HUMAN 263 ILVTAHEDGHLRLW 276 5899********** PP == domain 3 score: 8.6 bits; conditional E-value: 0.23 EEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGHss..vtslafspdgawlasGsdDgtvriW 37 l ++++H s + + + +++ ++++s Dg+vr+W tr|H0Y6L4|H0Y6L4_HUMAN 339 LLSWRAH-SleIIQVIYVEEKQVVLTASIDGSVRLW 373 5666777.33444665555666689*********** PP >> sp|Q8IZQ1-2|WDFY3_HUMAN Isoform 2 of WD repeat and FYVE domain-containing protein 3 OS=Homo sapiens GN=WDFY3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.3 0.0018 0.15 7 38 .] 3106 3138 .. 3099 3138 .. 0.79 2 ? 10.9 0.2 0.042 3.4 5 37 .. 3189 3227 .. 3185 3228 .. 0.76 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.0018 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH + vt+ s + ++sGs+D+t+ iWd sp|Q8IZQ1-2|WDFY3_HUMAN 3106 LLGHtDTVTCATASLAYHIIVSGSRDRTCIIWD 3138 559*666**996666666689***********9 PP == domain 2 score: 10.9 bits; conditional E-value: 0.042 EEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 t+tG + + +++ s + w +++G+ Dg vr+W sp|Q8IZQ1-2|WDFY3_HUMAN 3189 NTFTGRsQQIICCCMSEMNEWdtqnvIVTGHSDGVVRFW 3227 67888844465788777888888887789*88******* PP >> tr|H3BRJ5|H3BRJ5_HUMAN Uncharacterized protein OS=Homo sapiens PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.4 0.043 3.5 6 38 .] 354 387 .. 349 387 .. 0.86 2 ? 11.7 0.0 0.024 1.9 10 29 .. 399 419 .. 390 429 .. 0.78 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.043 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++H++ + +++++ +++++s+++D++ ++Wd tr|H3BRJ5|H3BRJ5_HUMAN 354 QWKAHDGiILKVDWNSVNDLILSAGEDCKYKVWD 387 4679955479**99999****************9 PP == domain 2 score: 11.7 bits; conditional E-value: 0.024 S.SSEEEEEEETTSSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGs 29 H ++ts+a+ pdg ++a Gs tr|H3BRJ5|H3BRJ5_HUMAN 399 HeHPITSVAWAPDGELFAVGS 419 4338**************998 PP >> sp|Q8IZQ1|WDFY3_HUMAN WD repeat and FYVE domain-containing protein 3 OS=Homo sapiens GN=WDFY3 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.3 0.0018 0.15 7 38 .] 3123 3155 .. 3116 3155 .. 0.79 2 ? 10.9 0.2 0.042 3.4 5 37 .. 3206 3244 .. 3202 3245 .. 0.76 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.0018 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l GH + vt+ s + ++sGs+D+t+ iWd sp|Q8IZQ1|WDFY3_HUMAN 3123 LLGHtDTVTCATASLAYHIIVSGSRDRTCIIWD 3155 559*666**996666666689***********9 PP == domain 2 score: 10.9 bits; conditional E-value: 0.042 EEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 t+tG + + +++ s + w +++G+ Dg vr+W sp|Q8IZQ1|WDFY3_HUMAN 3206 NTFTGRsQQIICCCMSEMNEWdtqnvIVTGHSDGVVRFW 3244 67888844465788777888888887789*88******* PP >> tr|J3QRG0|J3QRG0_HUMAN U3 small nucleolar RNA-associated protein 18 homolog (Fragment) OS=Homo sapiens GN=UTP18 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.1 0.3 25 26 38 .] 8 19 .. 1 19 [. 0.73 2 ? 10.8 0.0 0.045 3.6 15 38 .] 39 62 .. 23 62 .. 0.82 3 ? 4.2 0.0 5.3 4.3e+02 12 29 .. 84 101 .. 70 110 .. 0.85 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.3 EEEETTSEEEEEE CS WD40 26 asGsdDgtvriWd 38 as++ Dg v++Wd tr|J3QRG0|J3QRG0_HUMAN 8 ASSG-DGEVYVWD 19 4566.*******9 PP == domain 2 score: 10.8 bits; conditional E-value: 0.045 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 s+a+s++g+++a+Gs g v i++ tr|J3QRG0|J3QRG0_HUMAN 39 SIATSRNGQYVACGSNCGVVNIYN 62 678************888888886 PP == domain 3 score: 4.2 bits; conditional E-value: 5.3 SEEEEEEETTSSEEEEEE CS WD40 12 svtslafspdgawlasGs 29 +vtsl f+p la +s tr|J3QRG0|J3QRG0_HUMAN 84 GVTSLTFNPTTEILAIAS 101 599********9999777 PP >> tr|F8WB94|F8WB94_HUMAN WD repeat-containing protein 35 OS=Homo sapiens GN=WDR35 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 0.0 0.17 14 14 36 .. 18 40 .. 9 40 .. 0.89 2 ? 7.1 0.0 0.68 55 5 37 .. 65 98 .. 62 99 .. 0.89 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.17 EEEEEETTSSEEEEEETTSEEEE CS WD40 14 tslafspdgawlasGsdDgtvri 36 ++++++++ ++a+G++Dg +++ tr|F8WB94|F8WB94_HUMAN 18 QCVSWNKEQGFIACGGEDGLLKV 40 7******************9986 PP == domain 2 score: 7.1 bits; conditional E-value: 0.68 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+GH +sv + ++ + l++++++g + +W tr|F8WB94|F8WB94_HUMAN 65 QTLEGHsGSVQVVTWNEQYQKLTTSDENGLIIVW 98 699***777*99989999999*99999******* PP >> tr|D6RCR1|D6RCR1_HUMAN Uncharacterized protein OS=Homo sapiens GN=WDR64 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.014 1.1 13 37 .. 330 350 .. 316 351 .. 0.75 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ + +++G+dD+ +r+W tr|D6RCR1|D6RCR1_HUMAN 330 CYCV----KANVIVTGGDDKVIRLW 350 5566....778899*********** PP >> tr|H0Y9T1|H0Y9T1_HUMAN THO complex subunit 3 (Fragment) OS=Homo sapiens GN=THOC3 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.1 9e-07 7.3e-05 6 38 .] 3 36 .. 1 36 [. 0.88 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 9e-07 EEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH..ssvtslafspdgawlasGsdDgtvriWd 38 ++ +H +++ +++f+p g+++a+Gs D v +Wd tr|H0Y9T1|H0Y9T1_HUMAN 3 SINAHpsNCI-CIKFDPMGKYFATGSADALVSLWD 36 5679985558.***********************9 PP >> tr|H0YDI6|H0YDI6_HUMAN WD repeat-containing protein 78 (Fragment) OS=Homo sapiens GN=WDR78 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 7 5.7e+02 12 38 .] 304 331 .. 294 331 .. 0.76 2 ? 4.5 0.3 4.4 3.5e+02 9 37 .. 434 465 .. 427 466 .. 0.64 3 ? 12.8 0.0 0.01 0.84 12 38 .] 481 508 .. 471 508 .. 0.84 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 7 SEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 12 svtslafspdgawl.asGsdDgtvriWd 38 +vt+++fs + l a G +gt+ i++ tr|H0YDI6|H0YDI6_HUMAN 304 GVTAVDFSIGAPNLlAVGYHNGTIAIYN 331 39999988888886257867****9987 PP == domain 2 score: 4.5 bits; conditional E-value: 4.4 SS.SS.EEEEEEETTSSE.......EEEEETTSEEEEE CS WD40 9 GH.ss.vtslafspdgaw.......lasGsdDgtvriW 37 H ++ v+ + +w ++s+s D v iW tr|H0YDI6|H0YDI6_HUMAN 434 FHpKGpVYKV------TWnpfchdvFLSCSADWGVIIW 465 3442235555......336666666679999******* PP == domain 3 score: 12.8 bits; conditional E-value: 0.01 S.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriWd 38 s v+++a+sp +++++++ + v iWd tr|H0YDI6|H0YDI6_HUMAN 481 SvVYDVAWSPKSSYIFAAANENRVEIWD 508 447************98988*******9 PP >> tr|E7ESI5|E7ESI5_HUMAN TBC1 domain family member 31 OS=Homo sapiens GN=TBC1D31 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.2 0.034 2.8 8 38 .] 18 48 .. 10 48 .. 0.87 2 ? 6.2 0.0 1.3 1e+02 18 37 .. 117 136 .. 106 137 .. 0.88 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.034 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH ssv s++++ +g++ ++ s t +Wd tr|E7ESI5|E7ESI5_HUMAN 18 RGHeSSVFSISVHASGKYAITTS-SDTAQLWD 48 8**999************99989.88888887 PP == domain 2 score: 6.2 bits; conditional E-value: 1.3 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 + +dg+ la+G++ +++++W tr|E7ESI5|E7ESI5_HUMAN 117 VTRDGRILAAGGKSNHLHLW 136 5889**************** PP >> tr|G3V2M9|G3V2M9_HUMAN Protein NEDD1 (Fragment) OS=Homo sapiens GN=NEDD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.4 0.00023 0.019 7 34 .. 28 60 .. 22 62 .. 0.73 2 ? 3.8 0.0 7.3 5.9e+02 14 34 .. 81 101 .] 71 101 .] 0.88 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 0.00023 EESS.SS..EEEEEEETTSSEEEEE..ETTSEE CS WD40 7 ltGH.ss..vtslafspdgawlasG..sdDgtv 34 + H s+ ++s+++s+++++l+++ s D+ v tr|G3V2M9|G3V2M9_HUMAN 28 FNPHtSPhgISSICWSSNNNFLVTAssSGDKIV 60 556755577*************86522348876 PP == domain 2 score: 3.8 bits; conditional E-value: 7.3 EEEEEETTSSEEEEEETTSEE CS WD40 14 tslafspdgawlasGsdDgtv 34 t++ ++ + +l+sG+ ++tv tr|G3V2M9|G3V2M9_HUMAN 81 TCVNLNSTSMYLVSGGLNNTV 101 79999999999****988886 PP >> sp|Q5VU92|DC121_HUMAN DDB1- and CUL4-associated factor 12-like protein 1 OS=Homo sapiens GN=DCAF12L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 6.7 5.4e+02 12 31 .. 151 170 .. 143 172 .. 0.84 2 ! 16.0 1.6 0.001 0.082 6 37 .. 189 220 .. 185 221 .. 0.74 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 6.7 SEEEEEEETTSSEEEEEETT CS WD40 12 svtslafspdgawlasGsdD 31 +++++ +p++++la+G+++ sp|Q5VU92|DC121_HUMAN 151 GIHAIELNPSKTLLATGGEN 170 599999***********965 PP == domain 2 score: 16.0 bits; conditional E-value: 0.001 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 GH +++ ++a+ +d +sGs+Dgtv +W sp|Q5VU92|DC121_HUMAN 189 DRHGHkDWIFAVAWLSDTVA-VSGSRDGTVALW 220 556**666****55555554.48********** PP >> tr|H0Y6V0|H0Y6V0_HUMAN Dynein intermediate chain 1, axonemal (Fragment) OS=Homo sapiens GN=DNAI1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 1.7 1.5e-05 0.0012 2 38 .] 35 73 .. 34 73 .. 0.87 2 ? 3.6 0.0 8.3 6.8e+02 11 32 .. 87 109 .. 77 110 .. 0.75 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 1.5e-05 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 q l t+++H sv ++++p+++ ++ s+s D tv+iWd tr|H0Y6V0|H0Y6V0_HUMAN 35 QFLDTYDAHnMSVDTVSWNPYHTKVFmSCSSDWTVKIWD 73 56789****777************8558877*******9 PP == domain 2 score: 3.6 bits; conditional E-value: 8.3 SSEEEEEEETTSSEEEEE.ETTS CS WD40 11 ssvtslafspdgawlasG.sdDg 32 s v ++a+ p+++ ++++ + Dg tr|H0Y6V0|H0Y6V0_HUMAN 87 SAVGDVAWAPYSSTVFAAvTTDG 109 44899*********986654476 PP >> sp|P57081-3|WDR4_HUMAN Isoform 3 of tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 OS=Homo sapien # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.31 25 15 36 .. 4 25 .. 2 27 .. 0.91 2 ! 14.9 0.0 0.0023 0.18 9 37 .. 40 70 .. 32 71 .. 0.66 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.31 EEEEETTSSEEEEEETTSEEEE CS WD40 15 slafspdgawlasGsdDgtvri 36 ++a+spd ++++++++D ++r+ sp|P57081-3|WDR4_HUMAN 4 DVAVSPDDRFILTADRDEKIRV 25 7999****************98 PP == domain 2 score: 14.9 bits; conditional E-value: 0.0023 SS.SSEEEEEEETTSSE.EEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgaw.lasGsdDgtvriW 37 GH +v+ +++ p ++ l+s+s Dgt+r+W sp|P57081-3|WDR4_HUMAN 40 GHtEFVSRISVVPTQPGlLLSSSGDGTLRLW 70 897668888755555552335544******* PP >> tr|D6RJA5|D6RJA5_HUMAN WD repeat-containing protein 41 (Fragment) OS=Homo sapiens GN=WDR41 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.0 2.8e-06 0.00022 3 37 .. 88 120 .. 86 121 .. 0.88 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 2.8e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 c++t +H s+v ++a p+ +++ s+s+Dg+vriW tr|D6RJA5|D6RJA5_HUMAN 88 CQKT--AHdSNVLHVARLPNRQLI-SCSEDGSVRIW 120 7777..9*777************7.7999******* PP >> sp|Q96DN5|TBC31_HUMAN TBC1 domain family member 31 OS=Homo sapiens GN=TBC1D31 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 4.6 3.7e+02 15 38 .] 47 70 .. 33 70 .. 0.87 2 ? 10.4 0.2 0.062 5 8 38 .] 123 153 .. 115 153 .. 0.87 3 ? 5.4 0.0 2.3 1.8e+02 18 37 .. 222 241 .. 211 242 .. 0.88 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 4.6 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 +af+ g+ l++G+ g+++++d sp|Q96DN5|TBC31_HUMAN 47 NVAFDGTGDCLIAGDHQGNIYVFD 70 588***********88*****998 PP == domain 2 score: 10.4 bits; conditional E-value: 0.062 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH ssv s++++ +g++ ++ s t +Wd sp|Q96DN5|TBC31_HUMAN 123 RGHeSSVFSISVHASGKYAITTS-SDTAQLWD 153 8**999************99989.88888887 PP == domain 3 score: 5.4 bits; conditional E-value: 2.3 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 + +dg+ la+G++ +++++W sp|Q96DN5|TBC31_HUMAN 222 VTRDGRILAAGGKSNHLHLW 241 5889**************** PP >> sp|Q13216-2|ERCC8_HUMAN Isoform 2 of DNA excision repair protein ERCC-8 OS=Homo sapiens GN=ERCC8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.0 0.29 24 10 38 .] 42 72 .. 38 72 .. 0.79 2 ! 14.1 0.5 0.0041 0.33 9 38 .] 97 128 .. 84 128 .. 0.71 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.29 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H ++++ l+ + +g++++sG+ Dg + ++d sp|Q13216-2|ERCC8_HUMAN 42 HgGGINTLDiEPVEGRYMLSGGSDGVIVLYD 72 64457777666678999999988******98 PP == domain 2 score: 14.1 bits; conditional E-value: 0.0041 SS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawla.sGsdDgtvriWd 38 H sv +++ p+ + ++ s+s D+t+++Wd sp|Q13216-2|ERCC8_HUMAN 97 VHrYSVETVQWYPHDTGMFtSSSFDKTLKVWD 128 454448888766666665516678*******9 PP >> tr|J3QR85|J3QR85_HUMAN U3 small nucleolar RNA-associated protein 18 homolog (Fragment) OS=Homo sapiens GN=UTP18 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.3 0.0051 0.41 17 38 .] 45 69 .. 1 69 [. 0.76 2 ? 6.5 0.0 1 83 15 29 .. 89 103 .. 73 108 .. 0.80 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.0051 E...EETTSSEEEEEETTSEEEEEE CS WD40 17 a...fspdgawlasGsdDgtvriWd 38 a fs+d++ + ++s Dg v++Wd tr|J3QR85|J3QR85_HUMAN 45 AastFSSDSKKVYASSGDGEVYVWD 69 25569999***976666*******9 PP == domain 2 score: 6.5 bits; conditional E-value: 1 EEEEETTSSEEEEEE CS WD40 15 slafspdgawlasGs 29 s+a+s++g+++a+G+ tr|J3QR85|J3QR85_HUMAN 89 SIATSRNGQYVACGC 103 678*********996 PP >> sp|Q8NEZ3-2|WDR19_HUMAN Isoform 2 of WD repeat-containing protein 19 OS=Homo sapiens GN=WDR19 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 3.8 3.1e+02 21 38 .] 25 42 .. 20 42 .. 0.84 2 ? 4.2 0.1 5.4 4.4e+02 15 38 .] 57 83 .. 44 83 .. 0.77 3 ? 9.3 0.0 0.13 10 8 36 .. 272 300 .. 265 302 .. 0.85 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 3.8 TSSEEE.EEETTSEEEEEE CS WD40 21 dgawla.sGsdDgtvriWd 38 +g++la +G D v+i+d sp|Q8NEZ3-2|WDR19_HUMAN 25 SGNYLAvTGA-DYIVKIFD 42 6899974777.******98 PP == domain 2 score: 4.2 bits; conditional E-value: 5.4 EEE..EETTSSEEE.EEETTSEEEEEE CS WD40 15 sla..fspdgawla.sGsdDgtvriWd 38 ++a +++dg+ la + + +++Wd sp|Q8NEZ3-2|WDR19_HUMAN 57 CVAmdWDKDGDVLAvIAEKSSCIYLWD 83 44555*******974678899999998 PP == domain 3 score: 9.3 bits; conditional E-value: 0.13 ESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvri 36 + H ++ ts+a+s+ + +a+++ D+ ++i sp|Q8NEZ3-2|WDR19_HUMAN 272 RNHkDNLTSIAVSQTLNKVATCG-DNCIKI 300 569555*****************.****98 PP >> tr|D6R9P6|D6R9P6_HUMAN WD repeat domain 19, isoform CRA_a OS=Homo sapiens GN=WDR19 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 3.8 3.1e+02 21 38 .] 25 42 .. 20 42 .. 0.84 2 ? 4.2 0.1 5.4 4.4e+02 15 38 .] 57 83 .. 44 83 .. 0.77 3 ? 9.3 0.0 0.13 10 8 36 .. 272 300 .. 265 302 .. 0.85 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 3.8 TSSEEE.EEETTSEEEEEE CS WD40 21 dgawla.sGsdDgtvriWd 38 +g++la +G D v+i+d tr|D6R9P6|D6R9P6_HUMAN 25 SGNYLAvTGA-DYIVKIFD 42 6899974777.******98 PP == domain 2 score: 4.2 bits; conditional E-value: 5.4 EEE..EETTSSEEE.EEETTSEEEEEE CS WD40 15 sla..fspdgawla.sGsdDgtvriWd 38 ++a +++dg+ la + + +++Wd tr|D6R9P6|D6R9P6_HUMAN 57 CVAmdWDKDGDVLAvIAEKSSCIYLWD 83 44555*******974678899999998 PP == domain 3 score: 9.3 bits; conditional E-value: 0.13 ESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvri 36 + H ++ ts+a+s+ + +a+++ D+ ++i tr|D6R9P6|D6R9P6_HUMAN 272 RNHkDNLTSIAVSQTLNKVATCG-DNCIKI 300 569555*****************.****98 PP >> tr|D6RBZ7|D6RBZ7_HUMAN Coatomer subunit beta' (Fragment) OS=Homo sapiens GN=COPB2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.2 0.0 0.0038 0.3 13 38 .] 31 56 .. 18 56 .. 0.80 2 ? 5.5 0.0 2.1 1.7e+02 3 16 .. 62 76 .. 60 77 .] 0.82 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 0.0038 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v++ +f ++w+++G dD +r+++ tr|D6RBZ7|D6RBZ7_HUMAN 31 VRAAKFVARKNWVVTGADDMQIRVFN 56 7777899999**************97 PP == domain 2 score: 5.5 bits; conditional E-value: 2.1 EEEEEESSSS.EEEE CS WD40 3 clrtltGHss.vtsl 16 ++ +++Hs+ ++++ tr|D6RBZ7|D6RBZ7_HUMAN 62 RVHMFEAHSDyIRCI 76 5899****556***9 PP >> sp|Q9C0C7-4|AMRA1_HUMAN Isoform 4 of Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens GN=A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7 5.7e+02 16 36 .. 59 79 .. 58 80 .. 0.92 2 ! 21.9 1.0 1.4e-05 0.0011 1 38 [] 85 124 .. 85 124 .. 0.74 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7 EEEETTSSEEEEEETTSEEEE CS WD40 16 lafspdgawlasGsdDgtvri 36 lafspd ++las + +++++i sp|Q9C0C7-4|AMRA1_HUMAN 59 LAFSPDRTLLASTHVNHNIYI 79 68*********9999999987 PP == domain 2 score: 21.9 bits; conditional E-value: 1.4e-05 TEEEEEEESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+++l GH + +++ f+p + +asG+ Dg vriWd sp|Q9C0C7-4|AMRA1_HUMAN 85 GKCVHSLIGHrrT-PWCVTFHPTISGlIASGCLDGEVRIWD 124 79********844.4666444444443789999*******9 PP >> sp|Q8WV16-4|DCAF4_HUMAN Isoform 4 of DDB1- and CUL4-associated factor 4 OS=Homo sapiens GN=DCAF4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.013 1.1 10 38 .] 269 298 .. 262 298 .. 0.91 2 ? 9.3 0.0 0.13 10 2 38 .] 303 342 .. 302 342 .. 0.70 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H s vts++ +d ++l+++++ g++++Wd sp|Q8WV16-4|DCAF4_HUMAN 269 HdSAVTSVRILQDEQYLMASDMAGKIKLWD 298 9667**************9999*******9 PP == domain 2 score: 9.3 bits; conditional E-value: 0.13 EEEEEEESSSSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla......fspdgawlasGsdDgtvriWd 38 +c+r ++GH v+ a +g l++ + D+ riW+ sp|Q8WV16-4|DCAF4_HUMAN 303 KCVRQYEGH--VNEYAylplhvHEEEGI-LVAVGQDCYTRIWS 342 79*******..87776555553444444.555677*******5 PP >> sp|Q9C0C7-2|AMRA1_HUMAN Isoform 2 of Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens GN=A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7.2 5.9e+02 16 36 .. 59 79 .. 58 80 .. 0.92 2 ! 21.9 1.0 1.4e-05 0.0011 1 38 [] 85 124 .. 85 124 .. 0.74 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.2 EEEETTSSEEEEEETTSEEEE CS WD40 16 lafspdgawlasGsdDgtvri 36 lafspd ++las + +++++i sp|Q9C0C7-2|AMRA1_HUMAN 59 LAFSPDRTLLASTHVNHNIYI 79 68*********9999999987 PP == domain 2 score: 21.9 bits; conditional E-value: 1.4e-05 TEEEEEEESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+++l GH + +++ f+p + +asG+ Dg vriWd sp|Q9C0C7-2|AMRA1_HUMAN 85 GKCVHSLIGHrrT-PWCVTFHPTISGlIASGCLDGEVRIWD 124 79********844.4666444444443789999*******9 PP >> tr|Q86SY2|Q86SY2_HUMAN DDB1- and CUL4-associated factor 4 OS=Homo sapiens GN=DCAF4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 0.01 0.82 10 38 .] 199 228 .. 192 228 .. 0.91 2 ? 9.7 0.0 0.098 8 2 38 .] 233 272 .. 232 272 .. 0.70 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.01 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H s vts++ +d ++l+++++ g++++Wd tr|Q86SY2|Q86SY2_HUMAN 199 HdSAVTSVRILQDEQYLMASDMAGKIKLWD 228 9667**************9999*******9 PP == domain 2 score: 9.7 bits; conditional E-value: 0.098 EEEEEEESSSSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla......fspdgawlasGsdDgtvriWd 38 +c+r ++GH v+ a +g l++ + D+ riW+ tr|Q86SY2|Q86SY2_HUMAN 233 KCVRQYEGH--VNEYAylplhvHEEEGI-LVAVGQDCYTRIWS 272 79*******..87776555553444444.555677*******5 PP >> sp|Q9Y4P8-2|WIPI2_HUMAN Isoform 2 of WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 0.0 0.25 21 8 34 .. 181 208 .. 176 209 .. 0.90 2 ? 6.3 0.0 1.2 97 12 32 .. 232 252 .. 217 258 .. 0.77 3 ? 5.5 0.0 2.1 1.7e+02 7 38 .] 309 340 .. 303 340 .. 0.74 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.25 ESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtv 34 +H s+ +laf+ +g+ la++s++gtv sp|Q9Y4P8-2|WIPI2_HUMAN 181 PAHdSPLAALAFDASGTKLATASEKGTV 208 58988899******************98 PP == domain 2 score: 6.3 bits; conditional E-value: 1.2 SEEEEEEETTSSEEEEEETTS CS WD40 12 svtslafspdgawlasGsdDg 32 s++slafs dg +l+++s sp|Q9Y4P8-2|WIPI2_HUMAN 232 SICSLAFSMDGMFLSASSNTE 252 489***********8888555 PP == domain 3 score: 5.5 bits; conditional E-value: 2.1 EESSSSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtsla.fspdgawlasGsdDgtvriWd 38 + GH++++sla ++ ++l+ G Dg +++++ sp|Q9Y4P8-2|WIPI2_HUMAN 309 FCGHKNICSLAtIQKIPRLLV-GAADGYLYMYN 340 67**99999965444445555.988**999987 PP >> sp|Q9C0C7-3|AMRA1_HUMAN Isoform 3 of Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens GN=A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7.4 6e+02 16 36 .. 59 79 .. 58 80 .. 0.92 2 ! 21.9 1.0 1.4e-05 0.0012 1 38 [] 85 124 .. 85 124 .. 0.74 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.4 EEEETTSSEEEEEETTSEEEE CS WD40 16 lafspdgawlasGsdDgtvri 36 lafspd ++las + +++++i sp|Q9C0C7-3|AMRA1_HUMAN 59 LAFSPDRTLLASTHVNHNIYI 79 68*********9999999987 PP == domain 2 score: 21.9 bits; conditional E-value: 1.4e-05 TEEEEEEESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+++l GH + +++ f+p + +asG+ Dg vriWd sp|Q9C0C7-3|AMRA1_HUMAN 85 GKCVHSLIGHrrT-PWCVTFHPTISGlIASGCLDGEVRIWD 124 79********844.4666444444443789999*******9 PP >> sp|Q9C0C7-5|AMRA1_HUMAN Isoform 5 of Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens GN=A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 7.6 6.2e+02 16 36 .. 59 79 .. 58 80 .. 0.92 2 ! 21.8 1.0 1.5e-05 0.0012 1 38 [] 85 124 .. 85 124 .. 0.74 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 7.6 EEEETTSSEEEEEETTSEEEE CS WD40 16 lafspdgawlasGsdDgtvri 36 lafspd ++las + +++++i sp|Q9C0C7-5|AMRA1_HUMAN 59 LAFSPDRTLLASTHVNHNIYI 79 68*********9999999987 PP == domain 2 score: 21.8 bits; conditional E-value: 1.5e-05 TEEEEEEESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+++l GH + +++ f+p + +asG+ Dg vriWd sp|Q9C0C7-5|AMRA1_HUMAN 85 GKCVHSLIGHrrT-PWCVTFHPTISGlIASGCLDGEVRIWD 124 79********844.4666444444443789999*******9 PP >> sp|Q9Y4P8-4|WIPI2_HUMAN Isoform 4 of WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 0.0 0.26 21 8 34 .. 181 208 .. 176 209 .. 0.90 2 ? 6.2 0.0 1.2 1e+02 12 32 .. 232 252 .. 217 258 .. 0.77 3 ? 5.5 0.0 2.2 1.7e+02 7 38 .] 309 340 .. 303 340 .. 0.74 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.26 ESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtv 34 +H s+ +laf+ +g+ la++s++gtv sp|Q9Y4P8-4|WIPI2_HUMAN 181 PAHdSPLAALAFDASGTKLATASEKGTV 208 58988899******************98 PP == domain 2 score: 6.2 bits; conditional E-value: 1.2 SEEEEEEETTSSEEEEEETTS CS WD40 12 svtslafspdgawlasGsdDg 32 s++slafs dg +l+++s sp|Q9Y4P8-4|WIPI2_HUMAN 232 SICSLAFSMDGMFLSASSNTE 252 489***********8888555 PP == domain 3 score: 5.5 bits; conditional E-value: 2.2 EESSSSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtsla.fspdgawlasGsdDgtvriWd 38 + GH++++sla ++ ++l+ G Dg +++++ sp|Q9Y4P8-4|WIPI2_HUMAN 309 FCGHKNICSLAtIQKIPRLLV-GAADGYLYMYN 340 67**99999965444445555.988**999987 PP >> sp|Q8TAF3-5|WDR48_HUMAN Isoform 5 of WD repeat-containing protein 48 OS=Homo sapiens GN=WDR48 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.03 2.4 26 38 .] 18 30 .. 5 30 .. 0.84 2 ? 11.5 0.1 0.027 2.2 2 35 .. 35 69 .. 34 72 .. 0.88 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.03 EEEETTSEEEEEE CS WD40 26 asGsdDgtvriWd 38 +sGs Dgt+r+W+ sp|Q8TAF3-5|WDR48_HUMAN 18 LSGSSDGTIRLWS 30 47988*******5 PP == domain 2 score: 11.5 bits; conditional E-value: 0.027 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvr 35 +c+ t++ H +v++l++++ + + sG++D++++ sp|Q8TAF3-5|WDR48_HUMAN 35 RCIATYRVHdEGVWALQVNDAFTHVYSGGRDRKIY 69 79*******777****888888889*******996 PP >> sp|Q9Y4P8-3|WIPI2_HUMAN Isoform 3 of WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.0 0.22 18 8 34 .. 140 167 .. 135 168 .. 0.90 2 ? 6.5 0.0 1.1 85 12 33 .. 191 212 .. 176 217 .. 0.77 3 ? 5.7 0.0 1.8 1.5e+02 7 38 .] 268 299 .. 262 299 .. 0.74 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.22 ESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtv 34 +H s+ +laf+ +g+ la++s++gtv sp|Q9Y4P8-3|WIPI2_HUMAN 140 PAHdSPLAALAFDASGTKLATASEKGTV 167 58988899******************98 PP == domain 2 score: 6.5 bits; conditional E-value: 1.1 SEEEEEEETTSSEEEEEETTSE CS WD40 12 svtslafspdgawlasGsdDgt 33 s++slafs dg +l+++s t sp|Q9Y4P8-3|WIPI2_HUMAN 191 SICSLAFSMDGMFLSASSNTET 212 489***********88885555 PP == domain 3 score: 5.7 bits; conditional E-value: 1.8 EESSSSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtsla.fspdgawlasGsdDgtvriWd 38 + GH++++sla ++ ++l+ G Dg +++++ sp|Q9Y4P8-3|WIPI2_HUMAN 268 FCGHKNICSLAtIQKIPRLLV-GAADGYLYMYN 299 67**99999965444445555.988**999987 PP >> sp|Q8WV16-3|DCAF4_HUMAN Isoform 3 of DDB1- and CUL4-associated factor 4 OS=Homo sapiens GN=DCAF4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 0.015 1.2 10 38 .] 309 338 .. 302 338 .. 0.91 2 ? 9.2 0.0 0.15 12 2 38 .] 343 382 .. 342 382 .. 0.70 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.015 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H s vts++ +d ++l+++++ g++++Wd sp|Q8WV16-3|DCAF4_HUMAN 309 HdSAVTSVRILQDEQYLMASDMAGKIKLWD 338 9667**************9999*******9 PP == domain 2 score: 9.2 bits; conditional E-value: 0.15 EEEEEEESSSSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla......fspdgawlasGsdDgtvriWd 38 +c+r ++GH v+ a +g l++ + D+ riW+ sp|Q8WV16-3|DCAF4_HUMAN 343 KCVRQYEGH--VNEYAylplhvHEEEGI-LVAVGQDCYTRIWS 382 79*******..87776555553444444.555677*******5 PP >> sp|Q9C0C7|AMRA1_HUMAN Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens GN=AMBRA1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 7.6 6.2e+02 16 36 .. 59 79 .. 58 80 .. 0.92 2 ! 21.8 1.0 1.5e-05 0.0012 1 38 [] 85 124 .. 85 124 .. 0.74 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 7.6 EEEETTSSEEEEEETTSEEEE CS WD40 16 lafspdgawlasGsdDgtvri 36 lafspd ++las + +++++i sp|Q9C0C7|AMRA1_HUMAN 59 LAFSPDRTLLASTHVNHNIYI 79 68*********9999999987 PP == domain 2 score: 21.8 bits; conditional E-value: 1.5e-05 TEEEEEEESS..SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 1 gqclrtltGH..ssvtslafspdgaw.lasGsdDgtvriWd 38 g+c+++l GH + +++ f+p + +asG+ Dg vriWd sp|Q9C0C7|AMRA1_HUMAN 85 GKCVHSLIGHrrT-PWCVTFHPTISGlIASGCLDGEVRIWD 124 79********844.4666444444443789999*******9 PP >> sp|Q9P2L0-2|WDR35_HUMAN Isoform 2 of WD repeat-containing protein 35 OS=Homo sapiens GN=WDR35 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.0 0.24 19 14 36 .. 18 40 .. 9 40 .. 0.89 2 ? 6.6 0.0 0.96 78 5 37 .. 65 98 .. 62 99 .. 0.89 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.24 EEEEEETTSSEEEEEETTSEEEE CS WD40 14 tslafspdgawlasGsdDgtvri 36 ++++++++ ++a+G++Dg +++ sp|Q9P2L0-2|WDR35_HUMAN 18 QCVSWNKEQGFIACGGEDGLLKV 40 6******************9986 PP == domain 2 score: 6.6 bits; conditional E-value: 0.96 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+GH +sv + ++ + l++++++g + +W sp|Q9P2L0-2|WDR35_HUMAN 65 QTLEGHsGSVQVVTWNEQYQKLTTSDENGLIIVW 98 699***777*99989999999*99999******* PP >> tr|H0Y6G3|H0Y6G3_HUMAN WD repeat-containing protein 46 (Fragment) OS=Homo sapiens GN=WDR46 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 0.00043 0.035 4 38 .] 279 314 .. 276 314 .. 0.88 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 0.00043 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l ++ H ++v+++a+++ g+++a+++ D+ ++i+d tr|H0Y6G3|H0Y6G3_HUMAN 279 LAKILCHrGGVRAVAVDSTGTYMATSGLDHQLKIFD 314 5555689999**************9999******98 PP >> sp|Q9P2L0|WDR35_HUMAN WD repeat-containing protein 35 OS=Homo sapiens GN=WDR35 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.0 0.24 19 14 36 .. 18 40 .. 9 40 .. 0.89 2 ? 6.6 0.0 0.97 78 5 37 .. 65 98 .. 62 99 .. 0.89 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.24 EEEEEETTSSEEEEEETTSEEEE CS WD40 14 tslafspdgawlasGsdDgtvri 36 ++++++++ ++a+G++Dg +++ sp|Q9P2L0|WDR35_HUMAN 18 QCVSWNKEQGFIACGGEDGLLKV 40 6******************9986 PP == domain 2 score: 6.6 bits; conditional E-value: 0.97 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+GH +sv + ++ + l++++++g + +W sp|Q9P2L0|WDR35_HUMAN 65 QTLEGHsGSVQVVTWNEQYQKLTTSDENGLIIVW 98 699***777*99989999999*99999******* PP >> sp|O94979-5|SC31A_HUMAN Isoform 5 of Protein transport protein Sec31A OS=Homo sapiens GN=SEC31A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 8 6.5e+02 12 38 .] 84 102 .. 60 102 .. 0.86 2 ? 4.7 0.0 3.8 3.1e+02 10 38 .] 121 151 .. 115 151 .. 0.74 3 ? 4.9 0.0 3.4 2.7e+02 2 34 .. 251 285 .. 250 287 .. 0.73 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 8 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v+++ l++G+++g++ ++d sp|O94979-5|SC31A_HUMAN 84 DVSGV--------LIAGGENGNIILYD 102 47888........999*******9998 PP == domain 2 score: 4.7 bits; conditional E-value: 3.8 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H ++v++l+ + +++asG ++iWd sp|O94979-5|SC31A_HUMAN 121 HtGPVRALDvNIFQTNLVASGANESEIYIWD 151 65668888744444455789989*******9 PP == domain 3 score: 4.9 bits; conditional E-value: 3.4 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtv 34 ++lr+l+ H ++ ++a+s + l+s+++D ++ sp|O94979-5|SC31A_HUMAN 251 SPLRVLENHaRGILAIAWSMADPElLLSCGKDAKI 285 6899*****777****6444444446799999766 PP >> tr|H0YF49|H0YF49_HUMAN E3 ubiquitin-protein ligase RFWD2 (Fragment) OS=Homo sapiens GN=RFWD2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 1.7 1.4e+02 9 37 .. 140 168 .. 126 169 .. 0.80 2 ! 15.8 0.1 0.0012 0.094 10 38 .] 190 219 .. 181 219 .. 0.80 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 1.7 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 G s v+s+ f++d +++a ++ ++++++ tr|H0YF49|H0YF49_HUMAN 140 GS-SiVSSIEFDRDCDYFAIAGVTKKIKVY 168 44.348************977779999987 PP == domain 2 score: 15.8 bits; conditional E-value: 0.0012 SSSEEEEEEETTSSEEEEEET.TSEEEEEE CS WD40 10 HssvtslafspdgawlasGsd.DgtvriWd 38 s ++++++s++++ l+++sd gtv +Wd tr|H0YF49|H0YF49_HUMAN 190 NSKISCISWSSYHKNLLASSDyEGTVILWD 219 4449****99999998777644*******9 PP >> tr|J3KSQ3|J3KSQ3_HUMAN WD repeat and SOCS box-containing protein 1 OS=Homo sapiens GN=WSB1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.0 0.0 1.4e-06 0.00012 2 29 .. 15 43 .. 14 49 .. 0.84 Alignments for each domain: == domain 1 score: 25.0 bits; conditional E-value: 1.4e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs 29 + +++l+GH ++v+s+afspd+++l+s + tr|J3KSQ3|J3KSQ3_HUMAN 15 NMMKVLRGHqNWVYSCAFSPDSSMLCSVG 43 67899****999************98643 PP >> sp|Q6P2E9|EDC4_HUMAN Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.1 0.00015 0.012 6 37 .. 292 324 .. 287 325 .. 0.87 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 0.00015 EEESSSSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 6 tltGHssvtsla...fspdgawlasGsdDgtvriW 37 + +GH t+l+ spdg+ la++s Dg v++W sp|Q6P2E9|EDC4_HUMAN 292 VVKGH--STCLSegaLSPDGTVLATASHDGYVKFW 324 57899..489999999*********999******* PP >> tr|H7C4Y4|H7C4Y4_HUMAN WD repeat-containing protein 49 (Fragment) OS=Homo sapiens GN=WDR49 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.16 13 22 38 .] 28 43 .. 7 43 .. 0.80 2 ! 13.8 0.0 0.0052 0.42 2 38 .] 48 86 .. 47 86 .. 0.87 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.16 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 +++++G+ g vr+Wd tr|H7C4Y4|H7C4Y4_HUMAN 28 ANLVSCGG-SGYVRFWD 43 35566667.*******9 PP == domain 2 score: 13.8 bits; conditional E-value: 0.0052 EEEEEEESSSSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla..fspdgawlasGsdDgtvriWd 38 q+l ++ +Hs+v s+ +++ +++l++G+ Dg ++iW+ tr|H7C4Y4|H7C4Y4_HUMAN 48 QLLAEFLAHSGVGSIImsTDKMNRYLTTGDLDGWLKIWN 86 67888999*8899888778889999****99*******8 PP >> tr|H0YAG9|H0YAG9_HUMAN Intraflagellar transport protein 122 homolog (Fragment) OS=Homo sapiens GN=IFT122 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 0.075 6 13 34 .. 2 32 .. 1 34 [. 0.78 2 ! 14.8 0.0 0.0025 0.2 2 24 .. 31 54 .. 30 66 .. 0.80 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.075 EEEEEEETTSSE..EEEEET.......TSEE CS WD40 13 vtslafspdgaw..lasGsd.......Dgtv 34 ++++af pdg+ la+Gs+ Dgt+ tr|H0YAG9|H0YAG9_HUMAN 2 INDIAFKPDGTQliLAAGSRllvydtsDGTL 32 89**********5446998666666778886 PP == domain 2 score: 14.8 bits; conditional E-value: 0.0025 EEEEEEESSSS.EEEEEEETTSSE CS WD40 2 qclrtltGHss.vtslafspdgaw 24 ++l+ l+GH++ v+++a+ +dg+ tr|H0YAG9|H0YAG9_HUMAN 31 TLLQPLKGHKDtVYCVAYAKDGNE 54 67899****555*****9999986 PP >> sp|Q9Y4P8-6|WIPI2_HUMAN Isoform 6 of WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.27 22 8 34 .. 199 226 .. 194 227 .. 0.90 2 ? 6.2 0.0 1.3 1e+02 12 32 .. 250 270 .. 235 276 .. 0.77 3 ? 5.4 0.0 2.2 1.8e+02 7 38 .] 327 358 .. 321 358 .. 0.74 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.27 ESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtv 34 +H s+ +laf+ +g+ la++s++gtv sp|Q9Y4P8-6|WIPI2_HUMAN 199 PAHdSPLAALAFDASGTKLATASEKGTV 226 58988899******************98 PP == domain 2 score: 6.2 bits; conditional E-value: 1.3 SEEEEEEETTSSEEEEEETTS CS WD40 12 svtslafspdgawlasGsdDg 32 s++slafs dg +l+++s sp|Q9Y4P8-6|WIPI2_HUMAN 250 SICSLAFSMDGMFLSASSNTE 270 489***********8888555 PP == domain 3 score: 5.4 bits; conditional E-value: 2.2 EESSSSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtsla.fspdgawlasGsdDgtvriWd 38 + GH++++sla ++ ++l+ G Dg +++++ sp|Q9Y4P8-6|WIPI2_HUMAN 327 FCGHKNICSLAtIQKIPRLLV-GAADGYLYMYN 358 67**99999965444445555.988**999987 PP >> sp|Q9Y4P8-5|WIPI2_HUMAN Isoform 5 of WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 0.0 0.26 21 8 34 .. 194 221 .. 189 222 .. 0.90 2 ? 6.2 0.0 1.2 1e+02 12 32 .. 245 265 .. 230 271 .. 0.77 3 ? 5.5 0.0 2.2 1.8e+02 7 38 .] 322 353 .. 316 353 .. 0.74 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.26 ESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtv 34 +H s+ +laf+ +g+ la++s++gtv sp|Q9Y4P8-5|WIPI2_HUMAN 194 PAHdSPLAALAFDASGTKLATASEKGTV 221 58988899******************98 PP == domain 2 score: 6.2 bits; conditional E-value: 1.2 SEEEEEEETTSSEEEEEETTS CS WD40 12 svtslafspdgawlasGsdDg 32 s++slafs dg +l+++s sp|Q9Y4P8-5|WIPI2_HUMAN 245 SICSLAFSMDGMFLSASSNTE 265 489***********8888555 PP == domain 3 score: 5.5 bits; conditional E-value: 2.2 EESSSSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtsla.fspdgawlasGsdDgtvriWd 38 + GH++++sla ++ ++l+ G Dg +++++ sp|Q9Y4P8-5|WIPI2_HUMAN 322 FCGHKNICSLAtIQKIPRLLV-GAADGYLYMYN 353 67**99999965444445555.988**999987 PP >> sp|Q8WV16|DCAF4_HUMAN DDB1- and CUL4-associated factor 4 OS=Homo sapiens GN=DCAF4 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.018 1.4 10 38 .] 369 398 .. 362 398 .. 0.91 2 ? 8.9 0.0 0.17 14 2 38 .] 403 442 .. 402 442 .. 0.70 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.018 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H s vts++ +d ++l+++++ g++++Wd sp|Q8WV16|DCAF4_HUMAN 369 HdSAVTSVRILQDEQYLMASDMAGKIKLWD 398 9667**************9999*******9 PP == domain 2 score: 8.9 bits; conditional E-value: 0.17 EEEEEEESSSSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla......fspdgawlasGsdDgtvriWd 38 +c+r ++GH v+ a +g l++ + D+ riW+ sp|Q8WV16|DCAF4_HUMAN 403 KCVRQYEGH--VNEYAylplhvHEEEGI-LVAVGQDCYTRIWS 442 79*******..87776555553444444.555677*******5 PP >> tr|H0YAE4|H0YAE4_HUMAN WD repeat-containing protein 17 (Fragment) OS=Homo sapiens GN=WDR17 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.1 4.6e-06 0.00037 5 38 .] 137 171 .. 133 171 .. 0.84 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 4.6e-06 EEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 r l GH + +++f pd + l a++s Dgt+++Wd tr|H0YAE4|H0YAE4_HUMAN 137 RDL-GHvETIFDCKFKPDDPNLlATASFDGTIKVWD 171 555.9*888************7368899*******9 PP >> tr|G3V2S2|G3V2S2_HUMAN Protein NEDD1 OS=Homo sapiens GN=NEDD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.0 0.13 10 24 38 .] 2 16 .. 1 16 [. 0.93 2 ! 15.5 0.2 0.0015 0.12 5 32 .. 24 52 .. 20 58 .. 0.83 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.13 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +l+sG+ ++tv iWd tr|G3V2S2|G3V2S2_HUMAN 2 YLVSGGLNNTVNIWD 16 689***********9 PP == domain 2 score: 15.5 bits; conditional E-value: 0.0015 EEEESSSS.EEEEEEETTSSEEEEEETTS CS WD40 5 rtltGHss.vtslafspdgawlasGsdDg 32 r+l+ H++ vt++ ++ + ++asGs g tr|G3V2S2|G3V2S2_HUMAN 24 RSLKDHKDqVTCVTYNWNDCYIASGSLSG 52 78999*555****************9665 PP >> tr|H0Y329|H0Y329_HUMAN WD repeat domain phosphoinositide-interacting protein 4 (Fragment) OS=Homo sapiens GN=WDR45 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 0.00052 0.042 13 37 .. 167 191 .. 153 191 .. 0.84 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 0.00052 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++ fs+d+++l+++sd+gtv+i+ tr|H0Y329|H0Y329_HUMAN 167 LYCINFSHDSSFLCASSDKGTVHIF 191 78************99******995 PP >> sp|Q9Y4P8|WIPI2_HUMAN WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.28 22 8 34 .. 199 226 .. 194 227 .. 0.90 2 ? 6.2 0.0 1.3 1.1e+02 12 32 .. 250 270 .. 235 276 .. 0.77 3 ? 5.4 0.0 2.3 1.8e+02 7 38 .] 327 358 .. 321 358 .. 0.74 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.28 ESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtv 34 +H s+ +laf+ +g+ la++s++gtv sp|Q9Y4P8|WIPI2_HUMAN 199 PAHdSPLAALAFDASGTKLATASEKGTV 226 58988899******************98 PP == domain 2 score: 6.2 bits; conditional E-value: 1.3 SEEEEEEETTSSEEEEEETTS CS WD40 12 svtslafspdgawlasGsdDg 32 s++slafs dg +l+++s sp|Q9Y4P8|WIPI2_HUMAN 250 SICSLAFSMDGMFLSASSNTE 270 489***********8888555 PP == domain 3 score: 5.4 bits; conditional E-value: 2.3 EESSSSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHssvtsla.fspdgawlasGsdDgtvriWd 38 + GH++++sla ++ ++l+ G Dg +++++ sp|Q9Y4P8|WIPI2_HUMAN 327 FCGHKNICSLAtIQKIPRLLV-GAADGYLYMYN 358 67**99999965444445555.988**999987 PP >> sp|Q8WV16-5|DCAF4_HUMAN Isoform 5 of DDB1- and CUL4-associated factor 4 OS=Homo sapiens GN=DCAF4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.017 1.4 10 38 .] 363 392 .. 356 392 .. 0.91 2 ? 8.9 0.0 0.17 14 2 38 .] 397 436 .. 396 436 .. 0.70 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.017 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H s vts++ +d ++l+++++ g++++Wd sp|Q8WV16-5|DCAF4_HUMAN 363 HdSAVTSVRILQDEQYLMASDMAGKIKLWD 392 9667**************9999*******9 PP == domain 2 score: 8.9 bits; conditional E-value: 0.17 EEEEEEESSSSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla......fspdgawlasGsdDgtvriWd 38 +c+r ++GH v+ a +g l++ + D+ riW+ sp|Q8WV16-5|DCAF4_HUMAN 397 KCVRQYEGH--VNEYAylplhvHEEEGI-LVAVGQDCYTRIWS 436 79*******..87776555553444444.555677*******5 PP >> tr|Q5JNZ6|Q5JNZ6_HUMAN Histone-binding protein RBBP7 (Fragment) OS=Homo sapiens GN=RBBP7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.1 3.8e-06 0.00031 4 37 .. 26 61 .. 23 62 .. 0.85 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 3.8e-06 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriW 37 l + GH +++++++p+ +w++++ s+D+ iW tr|Q5JNZ6|Q5JNZ6_HUMAN 26 LFIHGGHtAKISDFSWNPNEPWVICSvSEDNIMQIW 61 56678**666************9977799******* PP >> sp|A2RUS2-2|DEND3_HUMAN Isoform 2 of DENN domain-containing protein 3 OS=Homo sapiens GN=DENND3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.1 0.0027 0.22 2 38 .] 925 965 .. 924 965 .. 0.78 2 ? 3.4 0.0 9.6 7.8e+02 6 38 .] 1110 1144 .. 1105 1144 .. 0.76 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.0027 EEEEEEESS.SSEEEEE...EETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgaw....lasGsdDgtvriWd 38 +c + lt+H ssvt+l + + s+s+Dg v +W+ sp|A2RUS2-2|DEND3_HUMAN 925 SCNKQLTAHcSSVTDLIvqdG----QEapsnVYSCSMDGMVLVWN 965 68999****999****54331....224666789**********8 PP == domain 2 score: 3.4 bits; conditional E-value: 9.6 EEESS.SSEEEEEEETTSSEEEEEE..TTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGs..dDgtvriWd 38 +l +H + v+ l s + ++++sGs + g+v iW+ sp|A2RUS2-2|DEND3_HUMAN 1110 ELVAHmDTVRTL-CSAEDRYVLSGSgrEEGKVAIWK 1144 677998889999.666667777886557******95 PP >> tr|D6RFM8|D6RFM8_HUMAN WD repeat-containing protein 36 (Fragment) OS=Homo sapiens GN=WDR36 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.3 0.00057 0.046 3 37 .. 25 58 .. 23 59 .. 0.89 2 ? 3.6 0.0 8.3 6.7e+02 15 38 .] 90 104 .. 71 104 .. 0.78 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 0.00057 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++t++GH ++ l +p g+ ++s + Dg + iW tr|D6RFM8|D6RFM8_HUMAN 25 IVHTFKGHkAEIHFL--QPFGDHIISVDTDGILIIW 58 69******655**99..********9988******* PP == domain 2 score: 3.6 bits; conditional E-value: 8.3 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 + l+ Gs+ g++ +W+ tr|D6RFM8|D6RFM8_HUMAN 90 KI--------LL-GSEQGSLQLWN 104 33........77.**********8 PP >> tr|H3BRM8|H3BRM8_HUMAN Cirhin (Fragment) OS=Homo sapiens GN=CIRH1A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.1 5.6 4.6e+02 9 26 .. 13 30 .. 4 36 .. 0.62 2 ? 12.7 0.0 0.011 0.93 5 29 .. 99 127 .. 95 136 .. 0.65 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 5.6 SS.SSEEEEEEETTSSEEE CS WD40 9 GH.ssvtslafspdgawla 26 G + + + + sp g+w+a tr|H3BRM8|H3BRM8_HUMAN 13 GPeNII-CSCISPCGSWIA 30 443335.3336******97 PP == domain 2 score: 12.7 bits; conditional E-value: 0.011 EEEESSSS.EEEEE...EETTSSEEEEEE CS WD40 5 rtltGHss.vtsla...fspdgawlasGs 29 + + +s+ v +++ +spdg+wla+++ tr|H3BRM8|H3BRM8_HUMAN 99 HAFQPQSGtVEAMCllaVSPDGNWLAASG 127 55544422487777778********9665 PP >> sp|A2RUS2|DEND3_HUMAN DENN domain-containing protein 3 OS=Homo sapiens GN=DENND3 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.1 0.0029 0.23 2 38 .] 977 1017 .. 976 1017 .. 0.78 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.0029 EEEEEEESS.SSEEEEE...EETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgaw....lasGsdDgtvriWd 38 +c + lt+H ssvt+l + + s+s+Dg v +W+ sp|A2RUS2|DEND3_HUMAN 977 SCNKQLTAHcSSVTDLIvqdG----QEapsnVYSCSMDGMVLVWN 1017 68999****999****54331....224666789**********8 PP >> tr|G3V3N9|G3V3N9_HUMAN Echinoderm microtubule-associated protein-like 1 (Fragment) OS=Homo sapiens GN=EML1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 1.3 2.8e-05 0.0022 2 38 .] 249 296 .. 248 296 .. 0.79 2 ? 6.5 0.6 1 84 12 38 .] 312 344 .. 300 344 .. 0.65 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 2.8e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE.....ET.....TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG.....sd.....DgtvriWd 38 q++r++ GH ++v +la++pd +a+G s+ ++vriWd tr|G3V3N9|G3V3N9_HUMAN 249 QLQRHYAGHnDDVKCLAVHPDRITIATGqvagtSKdgkqlPPHVRIWD 296 89*******666*************99755433335677788888887 PP == domain 2 score: 6.5 bits; conditional E-value: 1 S..EEEEEEETTSSE..EEEE..ETTSEEEEEE CS WD40 12 s..vtslafspdgaw..lasG..sdDgtvriWd 38 + vt++afs+++ l++ s D+ + +Wd tr|G3V3N9|G3V3N9_HUMAN 312 DraVTCIAFSKSNGGtnLCAVddSNDHVLSVWD 344 3569***955555555586554445*******9 PP >> tr|H0YAY3|H0YAY3_HUMAN DENN domain-containing protein 3 (Fragment) OS=Homo sapiens GN=DENND3 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.1 0.0029 0.23 2 38 .] 982 1022 .. 981 1022 .. 0.78 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.0029 EEEEEEESS.SSEEEEE...EETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgaw....lasGsdDgtvriWd 38 +c + lt+H ssvt+l + + s+s+Dg v +W+ tr|H0YAY3|H0YAY3_HUMAN 982 SCNKQLTAHcSSVTDLIvqdG----QEapsnVYSCSMDGMVLVWN 1022 68999****999****54331....224666789**********8 PP >> tr|Q5T0D5|Q5T0D5_HUMAN WD repeat-containing protein WRAP73 (Fragment) OS=Homo sapiens GN=WRAP73 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.56 45 16 28 .. 14 26 .. 4 33 .. 0.81 2 ? 4.7 0.0 3.8 3.1e+02 1 26 [. 168 194 .. 168 202 .. 0.84 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.56 EEEETTSSEEEEE CS WD40 16 lafspdgawlasG 28 ++fspdg++las+ tr|Q5T0D5|Q5T0D5_HUMAN 14 CKFSPDGKYLASC 26 35*********98 PP == domain 2 score: 4.7 bits; conditional E-value: 3.8 TEEEEEEESS.SSEEEEEEETTSSEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawla 26 +q+lr++++ ++ t++ + p+g la tr|Q5T0D5|Q5T0D5_HUMAN 168 WQLLRHFDTDtQDLTGIEWAPNGCVLA 194 6899999988788**********9985 PP >> tr|I3L2E7|I3L2E7_HUMAN Target of rapamycin complex subunit LST8 OS=Homo sapiens GN=MLST8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.0 0.0088 0.71 24 37 .. 14 27 .. 7 28 .. 0.82 2 ? 8.8 0.0 0.19 15 3 28 .. 34 59 .. 32 62 .. 0.82 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0088 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W tr|I3L2E7|I3L2E7_HUMAN 14 ILATAGYDHTVRFW 27 5888888******* PP == domain 2 score: 8.8 bits; conditional E-value: 0.19 EEEEEESS.SSEEEEEEETTSSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasG 28 c+rt H +sv++l + pd +++a++ tr|I3L2E7|I3L2E7_HUMAN 34 CTRTV-QHqDSVNALEVTPDRSMIAAA 59 78887.58788************9865 PP >> tr|K7EPZ5|K7EPZ5_HUMAN Nucleoporin SEH1 (Fragment) OS=Homo sapiens GN=SEH1L PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.2 0.019 1.6 26 38 .] 2 14 .. 1 14 [. 0.86 2 ! 14.6 3.5 0.0028 0.23 1 37 [. 21 60 .. 21 61 .. 0.85 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.019 EEEETTSEEEEEE CS WD40 26 asGsdDgtvriWd 38 a++s D++v++Wd tr|K7EPZ5|K7EPZ5_HUMAN 2 ATCSSDQSVKVWD 14 78877*******9 PP == domain 2 score: 14.6 bits; conditional E-value: 0.0028 TEEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw........lasGsdDgtvriW 37 + c+ ++++H +sv+ + +w las+s D+t +W tr|K7EPZ5|K7EPZ5_HUMAN 21 WHCTASWKTHsGSVWRV------TWahpefgqvLASCSFDRTAAVW 60 579999****777****......777777777799*********99 PP >> tr|E9PF32|E9PF32_HUMAN DENN domain-containing protein 3 OS=Homo sapiens GN=DENND3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.1 0.0031 0.25 2 38 .] 1057 1097 .. 1056 1097 .. 0.78 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 0.0031 EEEEEEESS.SSEEEEE...EETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgaw....lasGsdDgtvriWd 38 +c + lt+H ssvt+l + + s+s+Dg v +W+ tr|E9PF32|E9PF32_HUMAN 1057 SCNKQLTAHcSSVTDLIvqdG----QEapsnVYSCSMDGMVLVWN 1097 68999****999****54331....224666789**********8 PP >> tr|C9JBU3|C9JBU3_HUMAN WD repeat-containing protein 82 (Fragment) OS=Homo sapiens GN=WDR82 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.2 0.00054 0.044 22 38 .] 5 21 .. 1 21 [. 0.79 2 ? 5.0 0.0 3.1 2.5e+02 6 38 .] 32 61 .. 27 61 .. 0.70 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 0.00054 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 + ++sGs D+t+r+Wd tr|C9JBU3|C9JBU3_HUMAN 5 DDTFISGSLDKTIRLWD 21 445569**********9 PP == domain 2 score: 5.0 bits; conditional E-value: 3.1 EEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHssvtslafspdgawlasGsdDgtvriWd 38 +l G +v+s+ +p+g +a+G v+++d tr|C9JBU3|C9JBU3_HUMAN 32 HLQGK-PVCSF--DPEGLIFAAGVNSEMVKLYD 61 55555.67766..******99996566666665 PP >> tr|H0Y9E5|H0Y9E5_HUMAN Intraflagellar transport protein 122 homolog (Fragment) OS=Homo sapiens GN=IFT122 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.0 0.18 14 13 34 .. 2 32 .. 1 34 [. 0.77 2 ! 13.9 0.0 0.0047 0.38 2 25 .. 31 55 .. 30 60 .. 0.82 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.18 EEEEEEETTSSE..EEEEET.......TSEE CS WD40 13 vtslafspdgaw..lasGsd.......Dgtv 34 ++++af pdg+ la+Gs+ Dgt+ tr|H0Y9E5|H0Y9E5_HUMAN 2 INDIAFKPDGTQliLAAGSRllvydtsDGTL 32 89**********5446998666666778876 PP == domain 2 score: 13.9 bits; conditional E-value: 0.0047 EEEEEEESSSS.EEEEEEETTSSEE CS WD40 2 qclrtltGHss.vtslafspdgawl 25 ++l+ l+GH++ v+++a+ +dg+++ tr|H0Y9E5|H0Y9E5_HUMAN 31 TLLQPLKGHKDtVYCVAYAKDGTMM 55 67899****555****999999874 PP >> tr|E7EWW7|E7EWW7_HUMAN TBC1 domain family member 31 OS=Homo sapiens GN=TBC1D31 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.2 0.054 4.3 8 38 .] 18 48 .. 10 48 .. 0.87 2 ? 5.6 0.0 2 1.6e+02 18 37 .. 117 136 .. 106 137 .. 0.88 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.054 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH ssv s++++ +g++ ++ s t +Wd tr|E7EWW7|E7EWW7_HUMAN 18 RGHeSSVFSISVHASGKYAITTS-SDTAQLWD 48 8**999************99989.88888887 PP == domain 2 score: 5.6 bits; conditional E-value: 2 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 + +dg+ la+G++ +++++W tr|E7EWW7|E7EWW7_HUMAN 117 VTRDGRILAAGGKSNHLHLW 136 5889**************** PP >> tr|E7ERK7|E7ERK7_HUMAN TBC1 domain family member 31 OS=Homo sapiens GN=TBC1D31 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.2 0.055 4.4 8 38 .] 18 48 .. 10 48 .. 0.87 2 ? 5.6 0.0 2 1.6e+02 18 37 .. 117 136 .. 106 137 .. 0.88 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.055 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH ssv s++++ +g++ ++ s t +Wd tr|E7ERK7|E7ERK7_HUMAN 18 RGHeSSVFSISVHASGKYAITTS-SDTAQLWD 48 8**999************99989.88888887 PP == domain 2 score: 5.6 bits; conditional E-value: 2 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 + +dg+ la+G++ +++++W tr|E7ERK7|E7ERK7_HUMAN 117 VTRDGRILAAGGKSNHLHLW 136 5889**************** PP >> tr|G3V500|G3V500_HUMAN Echinoderm microtubule-associated protein-like 1 (Fragment) OS=Homo sapiens GN=EML1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 1.5 2.1e-05 0.0017 2 38 .] 231 278 .. 230 278 .. 0.79 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 2.1e-05 EEEEEEESS.SSEEEEEEETTSSEEEEE.....ET.....TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG.....sd.....DgtvriWd 38 q++r++ GH ++v +la++pd +a+G s+ ++vriWd tr|G3V500|G3V500_HUMAN 231 QLQRHYAGHnDDVKCLAVHPDRITIATGqvagtSKdgkqlPPHVRIWD 278 89*******666*************99755433335677788888887 PP >> tr|Q4G115|Q4G115_HUMAN DNAI2 protein OS=Homo sapiens GN=DNAI2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.2 4.5 3.6e+02 23 38 .] 135 150 .. 109 150 .. 0.63 2 ? 11.2 0.0 0.034 2.8 2 38 .] 212 249 .. 211 249 .. 0.75 3 ? 3.6 0.0 8.6 7e+02 13 38 .] 267 293 .. 260 293 .. 0.77 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 4.5 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 + +s+s Dg v+ Wd tr|Q4G115|Q4G115_HUMAN 135 TECFSASTDGQVMWWD 150 33456777*******9 PP == domain 2 score: 11.2 bits; conditional E-value: 0.034 EEEEEEESS.SSEEEEE.EETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgaw.lasGsdDgtvriWd 38 + + t+ GH +++++l+ + p + +++ + D t riW+ tr|Q4G115|Q4G115_HUMAN 212 KIVCTFPGHhGPIYALQrN-PFYPKnFLTVG-DWTARIWS 249 567899***999****963.33333456789.*******5 PP == domain 3 score: 3.6 bits; conditional E-value: 8.6 EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 13 vtslafspdgawla.sGsdDgtvriWd 38 t+ a+sp + ++ + +Dgt+ iWd tr|Q4G115|Q4G115_HUMAN 267 LTDAAWSPVRPTVFfTTRMDGTLDIWD 293 6777888888887548888*******9 PP >> tr|H0YAA2|H0YAA2_HUMAN Pleiotropic regulator 1 (Fragment) OS=Homo sapiens GN=PLRG1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.042 3.4 4 37 .. 8 41 .. 5 42 .. 0.87 2 ? 11.0 0.1 0.04 3.2 3 29 .. 48 74 .. 46 79 .. 0.81 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.042 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 tlt H +sv+++ +p + +asGs +++ W tr|H0YAA2|H0YAA2_HUMAN 8 RVTLTNHkKSVRAVVLHPRHYTFASGS-PDNIKQW 41 55899**999*****************.8888888 PP == domain 2 score: 11.0 bits; conditional E-value: 0.04 EEEEEESSSS.EEEEEEETTSSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGs 29 ++ l+GH+ ++ l +++dg ++ sG+ tr|H0YAA2|H0YAA2_HUMAN 48 FIQNLSGHNAiINTLTVNSDGVLV-SGD 74 57889***7757**********96.674 PP >> tr|D6RGZ2|D6RGZ2_HUMAN THO complex subunit 3 OS=Homo sapiens GN=THOC3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 0.5 1.1e-05 0.00087 4 36 .. 48 81 .. 39 82 .. 0.82 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 1.1e-05 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvri 36 +r++ +Hs v+s+a+s dg+ lasGs D+t + tr|D6RGZ2|D6RGZ2_HUMAN 48 TREFLAHSAkVHSVAWSCDGRRLASGSFDKTASV 81 5677788336*****************9**9765 PP >> tr|E5RFR9|E5RFR9_HUMAN Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (Fragment) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 1.4 1.1e+02 14 36 .. 9 32 .. 4 34 .. 0.73 2 ? 10.4 0.1 0.058 4.7 11 38 .] 65 91 .. 56 91 .. 0.89 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 1.4 EEEEEETTSSE..EEEEETTSEEEE CS WD40 14 tslafspdgaw..lasGsdDgtvri 36 t+ f+p++ + s+s +gt+r+ tr|E5RFR9|E5RFR9_HUMAN 9 TAAEFHPNSCNtfVYSSS-KGTIRL 32 555566666665588999.*****8 PP == domain 2 score: 10.4 bits; conditional E-value: 0.058 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fs++g+++++ d +v+iWd tr|E5RFR9|E5RFR9_HUMAN 65 SSISDVKFSHSGRYMMT-RDYLSVKIWD 91 46999***********6.89*******9 PP >> tr|H3BR38|H3BR38_HUMAN Target of rapamycin complex subunit LST8 OS=Homo sapiens GN=MLST8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.0 0.009 0.73 24 37 .. 14 27 .. 7 28 .. 0.82 2 ? 8.1 0.0 0.32 26 3 28 .. 34 60 .. 32 63 .. 0.78 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.009 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W tr|H3BR38|H3BR38_HUMAN 14 ILATAGYDHTVRFW 27 5888888******* PP == domain 2 score: 8.1 bits; conditional E-value: 0.32 EEEEEESS..SSEEEEEEETTSSEEEEE CS WD40 3 clrtltGH..ssvtslafspdgawlasG 28 c+rt H s v++l + pd +++a++ tr|H3BR38|H3BR38_HUMAN 34 CTRTVQ-HqdSQVNALEVTPDRSMIAAA 60 788875.75444************9865 PP >> sp|O15213|WDR46_HUMAN WD repeat-containing protein 46 OS=Homo sapiens GN=WDR46 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 0.001 0.081 5 38 .] 353 387 .. 349 387 .. 0.88 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 0.001 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ H ++v+++a+++ g+++a+++ D+ ++i+d sp|O15213|WDR46_HUMAN 353 AKILCHrGGVRAVAVDSTGTYMATSGLDHQLKIFD 387 555589999**************9999******98 PP >> tr|D6RGK8|D6RGK8_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1 OS=Homo sapiens GN=GNB2L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.0 9.5e-06 0.00077 4 38 .] 8 44 .. 5 44 .. 0.87 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 9.5e-06 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +tl+GH ++vt +a +++ ++++s+s+D+t+ +W+ tr|D6RGK8|D6RGK8_HUMAN 8 RGTLKGHnGWVTQIAtTPQFPDMILSASRDKTIIMWK 44 579****666****99888888899***********6 PP >> sp|Q92466-2|DDB2_HUMAN Isoform D1 of DNA damage-binding protein 2 OS=Homo sapiens GN=DDB2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.087 7 14 38 .] 115 140 .. 101 140 .. 0.93 2 ? 8.0 0.0 0.33 27 12 38 .] 204 230 .. 182 230 .. 0.85 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.087 EEEEEETTSSE.EEEEETTSEEEEEE CS WD40 14 tslafspdgaw.lasGsdDgtvriWd 38 tsla++p ++ +a Gs+ g +++W+ sp|Q92466-2|DDB2_HUMAN 115 TSLAWHPTHPStVAVGSKGGDIMLWN 140 89*9******99889**********8 PP == domain 2 score: 8.0 bits; conditional E-value: 0.33 SEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 12 svtsla.fspdgawlasGsdDgtvriWd 38 +++sl f+p g+ las++ ++ iW+ sp|Q92466-2|DDB2_HUMAN 204 GISSLNeFNPMGDTLASAM-GYHILIWS 230 4888889********9988.*******5 PP >> tr|F8VTY2|F8VTY2_HUMAN Nucleoporin Nup37 (Fragment) OS=Homo sapiens GN=NUP37 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.42 34 2 37 .. 64 107 .. 63 108 .. 0.80 2 ? 11.7 0.0 0.023 1.9 5 34 .. 118 149 .. 114 150 .. 0.83 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.42 EEEEEEESS.SSEEEEEEETTSSE........EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw........lasGsdDgtvriW 37 ++lrt+ H v ++a+sp+ ++ ++++ D ++r++ tr|F8VTY2|F8VTY2_HUMAN 64 KTLRTF-HHgVRVDGIAWSPETRLdslppvikFCTSAADMKIRLF 107 567787.4744489***************988677767****986 PP == domain 2 score: 11.7 bits; conditional E-value: 0.023 EEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 5 rtltGH.ssvtslafspdgaw.lasGsdDgtv 34 ++l+GH +++++l f+p +as sdD+t+ tr|F8VTY2|F8VTY2_HUMAN 118 KVLEGHtDFINGLVFDPKEGQeIASVSDDHTC 149 6899**777****988888887998899*998 PP >> tr|H7C3C8|H7C3C8_HUMAN Neurobeachin-like protein 1 (Fragment) OS=Homo sapiens GN=NBEAL1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 0.0012 0.1 2 36 .. 11 46 .. 10 47 .. 0.90 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 0.0012 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++ ++l GH + v s+ s + ++ +sGs+Dgtv i tr|H7C3C8|H7C3C8_HUMAN 11 KPFQILYGHtNEVLSVGISTELDMAVSGSRDGTVII 46 6789999**9889999999999***********976 PP >> tr|E9PDB0|E9PDB0_HUMAN Uncharacterized protein OS=Homo sapiens GN=WDR49 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 3.3 2.7e+02 12 38 .] 362 388 .. 352 388 .. 0.85 2 ? 11.7 0.0 0.023 1.9 2 38 .] 394 431 .. 393 431 .. 0.88 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 3.3 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +++++++++ +++a+++ +++v +W+ tr|E9PDB0|E9PDB0_HUMAN 362 GIHAFDYHSRLNLIATAGINNKVCLWN 388 5888989999999*************8 PP == domain 2 score: 11.7 bits; conditional E-value: 0.023 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++l GH sv +++f + + l+s s+D+ +r+Wd tr|E9PDB0|E9PDB0_HUMAN 394 KPVGVLWGHsASVIAVQFFVERKQLFSFSKDKVLRLWD 431 6788999**77788**99999999**88*********9 PP >> tr|C9K020|C9K020_HUMAN WD repeat-containing protein 6 (Fragment) OS=Homo sapiens GN=WDR6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 8.2e-05 0.0067 6 38 .] 236 269 .. 232 269 .. 0.88 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 8.2e-05 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++GH + + s+++ ++ +la++s+D++vriW+ tr|C9K020|C9K020_HUMAN 236 RISGHvGIIFSMSYLESKGLLATASEDRSVRIWK 269 568**6668***99999999*************6 PP >> tr|H7C355|H7C355_HUMAN Echinoderm microtubule-associated protein-like 3 (Fragment) OS=Homo sapiens GN=EML3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.4 2.4e-05 0.002 3 37 .. 72 108 .. 70 109 .. 0.90 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 2.4e-05 EEEEEESS.SSEEEEEEETTSSEEEE.EETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas.GsdDgtvriW 37 + r + GH s+vts++f +d + l+s G++D ++ W tr|H7C355|H7C355_HUMAN 72 PSRMYGGHgSHVTSVRFTHDDSHLVSlGGKDASIFQW 108 67899***999*****9999999998899******99 PP >> tr|K7ERF4|K7ERF4_HUMAN Coronin (Fragment) OS=Homo sapiens GN=CORO6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.1 1.8e-05 0.0014 2 38 .] 16 54 .. 15 54 .. 0.84 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.8e-05 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 +++ tl+GH + v l+++p + l++G+ D+ + iW+ tr|K7ERF4|K7ERF4_HUMAN 16 EPIITLEGHsKRVGILSWHPTARNvlLSAGG-DNVIIIWN 54 57899****888*9999*******4334778.*******8 PP >> tr|C9JNT2|C9JNT2_HUMAN DNA excision repair protein ERCC-8 (Fragment) OS=Homo sapiens GN=ERCC8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7.3 6e+02 26 38 .] 2 14 .. 1 14 [. 0.81 2 ! 15.1 0.5 0.0019 0.15 9 38 .] 39 70 .. 25 70 .. 0.71 3 ? 4.9 0.1 3.3 2.6e+02 1 16 [. 118 134 .] 118 134 .] 0.86 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.3 EEEETTSEEEEEE CS WD40 26 asGsdDgtvriWd 38 +sG+ Dg + ++d tr|C9JNT2|C9JNT2_HUMAN 2 LSGGSDGVIVLYD 14 47766******98 PP == domain 2 score: 15.1 bits; conditional E-value: 0.0019 SS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawla.sGsdDgtvriWd 38 H sv +++ p+ + ++ s+s D+t+++Wd tr|C9JNT2|C9JNT2_HUMAN 39 VHrYSVETVQWYPHDTGMFtSSSFDKTLKVWD 70 454448888766666665516678*******9 PP == domain 3 score: 4.9 bits; conditional E-value: 3.3 TEEEEEEESS.SSEEEE CS WD40 1 gqclrtltGH.ssvtsl 16 g+c ++l GH + + ++ tr|C9JNT2|C9JNT2_HUMAN 118 GSCSHILQGHrQEILAV 134 68********8888777 PP >> sp|Q3SXM0|DC4L1_HUMAN DDB1- and CUL4-associated factor 4-like protein 1 OS=Homo sapiens GN=DCAF4L1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.0 0.18 15 10 38 .] 269 298 .. 263 298 .. 0.90 2 ? 7.9 0.0 0.37 30 2 38 .] 303 342 .. 302 342 .. 0.64 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.18 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H s vts++ ++ + l+++++ g++++Wd sp|Q3SXM0|DC4L1_HUMAN 269 HdSAVTSVQILQEEQCLMASDMTGKIKLWD 298 9667****99999999*99999*******9 PP == domain 2 score: 7.9 bits; conditional E-value: 0.37 EEEEEEESS.SS.......EE...EEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ss.......vt...slafspdgawlasGsdDgtvriWd 38 +c+r ++GH + v+ ++ +++ + D+ riW+ sp|Q3SXM0|DC4L1_HUMAN 303 KCVRQYEGHvNEsaylplhVHeeeGI--------VVAVGQDCYTRIWS 342 79*******53334543333122233........666788*******5 PP >> sp|Q8NEZ3|WDR19_HUMAN WD repeat-containing protein 19 OS=Homo sapiens GN=WDR19 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.43 35 8 36 .. 272 300 .. 265 302 .. 0.85 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.43 ESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvri 36 + H ++ ts+a+s+ + +a+++ D+ ++i sp|Q8NEZ3|WDR19_HUMAN 272 RNHkDNLTSIAVSQTLNKVATCG-DNCIKI 300 569555*****************.****98 PP >> tr|B9TWZ6|B9TWZ6_HUMAN Mediator complex subunit MED16 variant MED16_i3 (Fragment) OS=Homo sapiens GN=MED16 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.8 5.2e-05 0.0042 7 38 .] 77 109 .. 71 109 .. 0.85 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 5.2e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H +t+l ++++g+ l+s++ Dg ++ W+ tr|B9TWZ6|B9TWZ6_HUMAN 77 PSEHhEAITCLEWDQSGSRLLSADADGQIKCWS 109 4567577****************99*******5 PP >> tr|B4DGE3|B4DGE3_HUMAN Protein transport protein Sec31B OS=Homo sapiens GN=SEC31B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.0 0.0053 0.43 10 38 .] 120 150 .. 111 150 .. 0.84 2 ? 6.5 0.0 1 81 2 34 .. 254 288 .. 253 290 .. 0.73 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.0053 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H + v++l+ ++ g++lasG D + iWd tr|B4DGE3|B4DGE3_HUMAN 120 HtGAVRALDlNPFQGNLLASGASDSEIFIWD 150 644599999999999999***66*******9 PP == domain 2 score: 6.5 bits; conditional E-value: 1 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtv 34 ++l++l+ H ++ s+++s+ a l+++ +D + tr|B4DGE3|B4DGE3_HUMAN 254 SPLKVLESHsRGILSVSWSQADAElLLTSAKDSQI 288 5899*****555****9665555525688888776 PP >> sp|Q5T6F0|DCA12_HUMAN DDB1- and CUL4-associated factor 12 OS=Homo sapiens GN=DCAF12 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 3 2.4e+02 11 31 .. 141 160 .. 132 163 .. 0.82 2 ? 10.2 1.0 0.07 5.7 8 37 .. 181 210 .. 173 211 .. 0.74 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 3 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 ++++++ +p+ ++la+G+ D sp|Q5T6F0|DCA12_HUMAN 141 CGIHAIELNPSRTLLATGG-D 160 4599999************.5 PP == domain 2 score: 10.2 bits; conditional E-value: 0.07 ESS.SSEEEEEEETTSSE.....EEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgaw.....lasGsdDgtvriW 37 +GH +++ s+ aw +sGs+Dg+ +W sp|Q5T6F0|DCA12_HUMAN 181 DGHkDWIFSI------AWisdtmAVSGSRDGSMGLW 210 59*666****......7744443358******9999 PP >> sp|Q9C0J8-2|WDR33_HUMAN Isoform 2 of pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens GN=WDR33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 5.6 4.5e+02 13 38 .] 122 147 .. 109 147 .. 0.81 2 ! 14.4 0.1 0.0033 0.27 5 37 .. 155 188 .. 151 189 .. 0.90 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 5.6 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 v +++ p+g+ l++G g +W+ sp|Q9C0J8-2|WDR33_HUMAN 122 VFVVRWTPEGRRLVTGASSGEFTLWN 147 55578***********5599999997 PP == domain 2 score: 14.4 bits; conditional E-value: 0.0033 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++l +H s+v+++ +s++ w+++++ g v+ W sp|Q9C0J8-2|WDR33_HUMAN 155 TILQAHdSPVRAMTWSHNDMWMLTADHGGYVKYW 188 5789**888****************88*****99 PP >> tr|H0YAG6|H0YAG6_HUMAN Intraflagellar transport protein 122 homolog (Fragment) OS=Homo sapiens GN=IFT122 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.0 0.08 6.5 13 34 .. 2 32 .. 1 34 [. 0.78 2 ? 11.3 0.0 0.032 2.6 2 19 .. 31 49 .. 30 64 .. 0.78 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.08 EEEEEEETTSSE..EEEEET.......TSEE CS WD40 13 vtslafspdgaw..lasGsd.......Dgtv 34 ++++af pdg+ la+Gs+ Dgt+ tr|H0YAG6|H0YAG6_HUMAN 2 INDIAFKPDGTQliLAAGSRllvydtsDGTL 32 89**********5446998666666778876 PP == domain 2 score: 11.3 bits; conditional E-value: 0.032 EEEEEEESSSS.EEEEEEE CS WD40 2 qclrtltGHss.vtslafs 19 ++l+ l+GH++ v+++a+ tr|H0YAG6|H0YAG6_HUMAN 31 TLLQPLKGHKDtVYCVAYA 49 67899****555****754 PP >> tr|F2Z2B5|F2Z2B5_HUMAN Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens GN=EML4 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 1.1 2.1e-05 0.0017 3 38 .] 90 127 .. 88 127 .. 0.80 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 2.1e-05 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 + +++++H s+vt ++f ++ + +++G++D ++ W+ tr|F2Z2B5|F2Z2B5_HUMAN 90 PSHKYSAHsSHVTNVSFTHNDSHlISTGGKDMSIIQWK 127 6899****888*****666666615699********95 PP >> tr|G8JLI5|G8JLI5_HUMAN WD repeat domain phosphoinositide-interacting protein 4 OS=Homo sapiens GN=WDR45 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 1.5 1.2e+02 12 38 .] 8 33 .. 2 33 .. 0.82 2 ? 8.9 0.0 0.18 15 6 34 .. 187 216 .. 181 221 .. 0.87 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 1.5 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +vtsl+f++d++ ++ + + vri++ tr|G8JLI5|G8JLI5_HUMAN 8 GVTSLRFNQDQSCFC-CAMETGVRIYN 33 49***********96.55599999997 PP == domain 2 score: 8.9 bits; conditional E-value: 0.18 EEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H s++ +++ ++ g+ +as+s +gt+ tr|G8JLI5|G8JLI5_HUMAN 187 TINAHqSDIACVSLNQPGTVVASASQKGTL 216 4569*999*****************88875 PP >> sp|Q9NQW1-2|SC31B_HUMAN Isoform 2 of Protein transport protein Sec31B OS=Homo sapiens GN=SEC31B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.0 0.0053 0.43 10 38 .] 120 150 .. 111 150 .. 0.84 2 ? 6.6 0.0 0.98 79 2 34 .. 250 284 .. 249 286 .. 0.73 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.0053 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H + v++l+ ++ g++lasG D + iWd sp|Q9NQW1-2|SC31B_HUMAN 120 HtGAVRALDlNPFQGNLLASGASDSEIFIWD 150 644599999999999999***66*******9 PP == domain 2 score: 6.6 bits; conditional E-value: 0.98 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtv 34 ++l++l+ H ++ s+++s+ a l+++ +D + sp|Q9NQW1-2|SC31B_HUMAN 250 SPLKVLESHsRGILSVSWSQADAElLLTSAKDSQI 284 5899*****555****9665555525688888776 PP >> tr|U3KQ43|U3KQ43_HUMAN Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens GN=MED16 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.8 6.8e-05 0.0055 7 38 .] 77 109 .. 71 109 .. 0.85 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 6.8e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H +t+l ++++g+ l+s++ Dg ++ W+ tr|U3KQ43|U3KQ43_HUMAN 77 PSEHhEAITCLEWDQSGSRLLSADADGQIKCWS 109 4567577****************99*******5 PP >> sp|Q9Y2X0-5|MED16_HUMAN Isoform 5 of Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens GN=MED16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.8 6.8e-05 0.0055 7 38 .] 77 109 .. 71 109 .. 0.85 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 6.8e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H +t+l ++++g+ l+s++ Dg ++ W+ sp|Q9Y2X0-5|MED16_HUMAN 77 PSEHhEAITCLEWDQSGSRLLSADADGQIKCWS 109 4567577****************99*******5 PP >> tr|H7C3C0|H7C3C0_HUMAN Intraflagellar transport 122 homolog (Chlamydomonas), isoform CRA_b OS=Homo sapiens GN=IFT122 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 3.6 2.9e+02 9 24 .. 24 40 .. 16 43 .. 0.86 2 ? 10.9 0.1 0.041 3.3 7 37 .. 167 198 .. 161 199 .. 0.79 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 3.6 SS.SSEEEEEEETTSSE CS WD40 9 GH.ssvtslafspdgaw 24 G s+++s++++p+++w tr|H7C3C0|H7C3C0_HUMAN 24 GSlSPIWSICWNPSSRW 40 56678***********9 PP == domain 2 score: 10.9 bits; conditional E-value: 0.041 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ tr|H7C3C0|H7C3C0_HUMAN 167 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 198 444545698888*****************876 PP >> tr|E9PKR7|E9PKR7_HUMAN Protein transport protein Sec31B OS=Homo sapiens GN=SEC31B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.0 0.0053 0.43 10 38 .] 120 150 .. 111 150 .. 0.84 2 ? 6.6 0.0 0.98 80 2 34 .. 251 285 .. 250 287 .. 0.73 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.0053 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H + v++l+ ++ g++lasG D + iWd tr|E9PKR7|E9PKR7_HUMAN 120 HtGAVRALDlNPFQGNLLASGASDSEIFIWD 150 644599999999999999***66*******9 PP == domain 2 score: 6.6 bits; conditional E-value: 0.98 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtv 34 ++l++l+ H ++ s+++s+ a l+++ +D + tr|E9PKR7|E9PKR7_HUMAN 251 SPLKVLESHsRGILSVSWSQADAElLLTSAKDSQI 285 5899*****555****9665555525688888776 PP >> tr|K7EQR0|K7EQR0_HUMAN Echinoderm microtubule-associated protein-like 2 (Fragment) OS=Homo sapiens GN=EML2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.5 0.00012 0.0096 2 38 .] 74 121 .. 73 121 .. 0.81 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 0.00012 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 q +r++ GH +++ +la +pd +a+G + ++vriWd tr|K7EQR0|K7EQR0_HUMAN 74 QRQRHYLGHnDDIKCLAIHPDMVTIATGqvaGTtkegkplPPHVRIWD 121 779******666*************99755422457778899999998 PP >> tr|H0Y9T9|H0Y9T9_HUMAN Protein transport protein Sec31A (Fragment) OS=Homo sapiens GN=SEC31A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 3.4 2.8e+02 12 38 .] 55 73 .. 46 73 .. 0.85 2 ? 6.2 0.0 1.3 1.1e+02 10 38 .] 92 122 .. 85 122 .. 0.74 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 3.4 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v+++ l++G+++g++ ++d tr|H0Y9T9|H0Y9T9_HUMAN 55 DVSGV--------LIAGGENGNIILYD 73 48888........999*******9998 PP == domain 2 score: 6.2 bits; conditional E-value: 1.3 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H ++v++l+ + +++asG ++iWd tr|H0Y9T9|H0Y9T9_HUMAN 92 HtGPVRALDvNIFQTNLVASGANESEIYIWD 122 65668888744444455789989*******9 PP >> tr|H0YDT9|H0YDT9_HUMAN Dynein intermediate chain 1, axonemal (Fragment) OS=Homo sapiens GN=DNAI1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 0.0028 0.23 7 38 .] 26 58 .. 21 58 .. 0.84 2 ? 4.6 0.8 4.1 3.3e+02 10 37 .. 77 109 .. 69 110 .. 0.72 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.0028 EESSSSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 7 ltGHssvtslafspdgawla.sGsdDgtvriWd 38 ++ s+v +l+ + d+++l+ G++Dg+v i++ tr|H0YDT9|H0YDT9_HUMAN 26 FSSNSGVMCLDIHVDHPYLVaVGHYDGNVAIYN 58 566677************863799*****9997 PP == domain 2 score: 4.6 bits; conditional E-value: 4.1 S.SSEEEEE.....EETTSSEEEEEETTSEEEEE CS WD40 10 H.ssvtsla.....fspdgawlasGsdDgtvriW 37 H ++v+ ++ +++ ++++ +s Dg + W tr|H0YDT9|H0YDT9_HUMAN 77 HsDPVWQVKwqkddMDQNLNFFSVSS-DGRIVSW 109 75559999666655666666687778.*999988 PP >> tr|D6RHZ5|D6RHZ5_HUMAN Protein transport protein Sec31A OS=Homo sapiens GN=SEC31A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 7.4 6e+02 10 38 .] 121 151 .. 115 151 .. 0.74 2 ? 4.0 0.0 6.5 5.3e+02 2 34 .. 251 285 .. 250 287 .. 0.73 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.4 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H ++v++l+ + +++asG ++iWd tr|D6RHZ5|D6RHZ5_HUMAN 121 HtGPVRALDvNIFQTNLVASGANESEIYIWD 151 65668888744444455789989*******9 PP == domain 2 score: 4.0 bits; conditional E-value: 6.5 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtv 34 ++lr+l+ H ++ ++a+s + l+s+++D ++ tr|D6RHZ5|D6RHZ5_HUMAN 251 SPLRVLENHaRGILAIAWSMADPElLLSCGKDAKI 285 6899*****777****6444444446799999766 PP >> sp|Q9H6U6-6|BCAS3_HUMAN Isoform 6 of Breast carcinoma-amplified sequence 3 OS=Homo sapiens GN=BCAS3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 0.012 0.94 4 34 .. 115 149 .. 113 151 .. 0.84 2 ? 6.0 0.2 1.5 1.2e+02 8 28 .. 169 194 .. 162 205 .. 0.74 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.012 EEEEESS.SSEEEEEEETTSSEEEE....EETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlas....GsdDgtv 34 + ++ +H ++v+++af+ +g +l++ G+ D +v sp|Q9H6U6-6|BCAS3_HUMAN 115 VAHFPAHeKPVCCMAFNTSGMLLVTtdtlGH-DFHV 149 6799*******************98555556.8776 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 ESS.SS....EEEEEEETTSSEEEEE CS WD40 8 tGH.ss....vtslafspdgawlasG 28 t H + v +++fs+d +w++ + sp|Q9H6U6-6|BCAS3_HUMAN 169 TLHrGEteakVQDICFSHDCRWVVVS 194 4454224567************9854 PP >> tr|K7ESE9|K7ESE9_HUMAN Breast carcinoma-amplified sequence 3 OS=Homo sapiens GN=BCAS3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 0.012 0.97 4 34 .. 115 149 .. 113 151 .. 0.84 2 ? 6.0 0.2 1.5 1.2e+02 8 28 .. 169 194 .. 162 205 .. 0.74 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.012 EEEEESS.SSEEEEEEETTSSEEEE....EETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlas....GsdDgtv 34 + ++ +H ++v+++af+ +g +l++ G+ D +v tr|K7ESE9|K7ESE9_HUMAN 115 VAHFPAHeKPVCCMAFNTSGMLLVTtdtlGH-DFHV 149 6799*******************98555556.8776 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 ESS.SS....EEEEEEETTSSEEEEE CS WD40 8 tGH.ss....vtslafspdgawlasG 28 t H + v +++fs+d +w++ + tr|K7ESE9|K7ESE9_HUMAN 169 TLHrGEteakVQDICFSHDCRWVVVS 194 4454224567************9854 PP >> sp|Q8IWG1-2|WDR63_HUMAN Isoform 2 of WD repeat-containing protein 63 OS=Homo sapiens GN=WDR63 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 0.0 0.14 12 11 38 .] 359 387 .. 350 387 .. 0.85 2 ? 10.8 4.1 0.044 3.5 11 38 .] 466 485 .. 428 485 .. 0.81 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.14 SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 11 ssvtslafspdgawlasGs.dDgtvriWd 38 +++ +++f+p+ + +++G+ +g + +Wd sp|Q8IWG1-2|WDR63_HUMAN 359 DDIFCFKFCPSDPNIIAGGcINGQIVMWD 387 4699***********999626*******9 PP == domain 2 score: 10.8 bits; conditional E-value: 0.044 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 s+++++ l+++s D+t+ +Wd sp|Q8IWG1-2|WDR63_HUMAN 466 SGICCQ--------LVTCSADCTICFWD 485 458888........99***********9 PP >> sp|Q9Y2X0-2|MED16_HUMAN Isoform 2 of Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens GN=MED16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.8 9e-05 0.0073 7 38 .] 77 109 .. 71 109 .. 0.85 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 9e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H +t+l ++++g+ l+s++ Dg ++ W+ sp|Q9Y2X0-2|MED16_HUMAN 77 PSEHhEAITCLEWDQSGSRLLSADADGQIKCWS 109 4567577****************99*******5 PP >> sp|Q8WVS4|WDR60_HUMAN WD repeat-containing protein 60 OS=Homo sapiens GN=WDR60 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.1 0.026 2.1 5 38 .] 691 725 .. 687 725 .. 0.82 2 ? 4.9 0.0 3.3 2.7e+02 13 36 .. 912 936 .. 898 938 .. 0.64 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.026 EEEESSSSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawla.sGsdDgtvriWd 38 ++l s vt+++ sp +a+l+ +G+ g+v +Wd sp|Q8WVS4|WDR60_HUMAN 691 KVLICESQVTCCCLSPLKAFLLfAGTAHGSVVVWD 725 45554455************8559*99*******9 PP == domain 2 score: 4.9 bits; conditional E-value: 3.3 EEEEEEETTSSEE.EEEETTSEEEE CS WD40 13 vtslafspdgawl.asGsdDgtvri 36 v+ ++fsp g + ++G+ Dg++r+ sp|Q8WVS4|WDR60_HUMAN 912 VNVIDFSPFGEPIfLAGCSDGSIRL 936 4555555555554235755*****8 PP >> tr|F5H6G7|F5H6G7_HUMAN Nucleolar protein 10 OS=Homo sapiens GN=NOL10 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.57 46 14 38 .] 6 31 .. 2 31 .. 0.85 2 ? 6.6 0.0 0.94 76 12 38 .] 221 249 .. 212 249 .. 0.82 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.57 EEEEEETTSSEE.EEEETTSEEEEEE CS WD40 14 tslafspdgawl.asGsdDgtvriWd 38 t +++s+dg+++ a+G++++ vr +d tr|F5H6G7|F5H6G7_HUMAN 6 TTIKVSKDGQYIlATGTYKPRVRCYD 31 8899*******6369999*****998 PP == domain 2 score: 6.6 bits; conditional E-value: 0.94 S...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvriWd 38 + s+ f+++ ++++s++ + v++W+ tr|F5H6G7|F5H6G7_HUMAN 221 YglpIKSVHFQDSLDLILSAD-SRIVKMWN 249 235599999*********878.*******8 PP >> sp|Q9BSC4|NOL10_HUMAN Nucleolar protein 10 OS=Homo sapiens GN=NOL10 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.52 42 13 38 .] 54 81 .. 47 81 .. 0.85 2 ? 6.5 0.0 1 83 12 38 .] 271 299 .. 262 299 .. 0.82 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.52 E.EEEEEETTSSEE.EEEETTSEEEEEE CS WD40 13 v.tslafspdgawl.asGsdDgtvriWd 38 v t +++s+dg+++ a+G++++ vr +d sp|Q9BSC4|NOL10_HUMAN 54 VcTTIKVSKDGQYIlATGTYKPRVRCYD 81 558899*******6369999*****998 PP == domain 2 score: 6.5 bits; conditional E-value: 1 S...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvriWd 38 + s+ f+++ ++++s++ + v++W+ sp|Q9BSC4|NOL10_HUMAN 271 YglpIKSVHFQDSLDLILSAD-SRIVKMWN 299 235599999*********878.*******8 PP >> sp|Q9Y2X0-3|MED16_HUMAN Isoform 3 of Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens GN=MED16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.8 9.2e-05 0.0075 7 38 .] 77 109 .. 71 109 .. 0.85 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 9.2e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H +t+l ++++g+ l+s++ Dg ++ W+ sp|Q9Y2X0-3|MED16_HUMAN 77 PSEHhEAITCLEWDQSGSRLLSADADGQIKCWS 109 4567577****************99*******5 PP >> tr|K7EJ50|K7EJ50_HUMAN Telomerase Cajal body protein 1 (Fragment) OS=Homo sapiens GN=WRAP53 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.0 6.3e-05 0.0051 14 37 .. 7 29 .. 3 30 .. 0.92 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 6.3e-05 EEEEEETTSSEEEEEETTSEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriW 37 +sl+fspdg+ l++G ++tvr++ tr|K7EJ50|K7EJ50_HUMAN 7 HSLCFSPDGSQLFCGF-NRTVRVF 29 59***********999.*****97 PP >> sp|Q9Y2X0|MED16_HUMAN Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens GN=MED16 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.8 9.5e-05 0.0077 7 38 .] 77 109 .. 71 109 .. 0.85 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 9.5e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H +t+l ++++g+ l+s++ Dg ++ W+ sp|Q9Y2X0|MED16_HUMAN 77 PSEHhEAITCLEWDQSGSRLLSADADGQIKCWS 109 4567577****************99*******5 PP >> tr|C9J355|C9J355_HUMAN WD repeat-containing protein 82 (Fragment) OS=Homo sapiens GN=WDR82 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.2 0.00022 0.018 22 38 .] 5 21 .. 1 21 [. 0.79 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 0.00022 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 + ++sGs D+t+r+Wd tr|C9J355|C9J355_HUMAN 5 DDTFISGSLDKTIRLWD 21 445579**********9 PP >> tr|K7EKS6|K7EKS6_HUMAN Mediator of RNA polymerase II transcription subunit 16 (Fragment) OS=Homo sapiens GN=MED16 PE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.8 4.3e-05 0.0035 7 38 .] 77 109 .. 71 109 .. 0.85 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 4.3e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H +t+l ++++g+ l+s++ Dg ++ W+ tr|K7EKS6|K7EKS6_HUMAN 77 PSEHhEAITCLEWDQSGSRLLSADADGQIKCWS 109 4567577****************99*******5 PP >> sp|Q8IWG1|WDR63_HUMAN WD repeat-containing protein 63 OS=Homo sapiens GN=WDR63 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.15 12 11 38 .] 398 426 .. 389 426 .. 0.85 2 ? 10.6 4.2 0.05 4.1 11 38 .] 505 524 .. 468 524 .. 0.81 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.15 SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 11 ssvtslafspdgawlasGs.dDgtvriWd 38 +++ +++f+p+ + +++G+ +g + +Wd sp|Q8IWG1|WDR63_HUMAN 398 DDIFCFKFCPSDPNIIAGGcINGQIVMWD 426 4699***********999626*******9 PP == domain 2 score: 10.6 bits; conditional E-value: 0.05 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 s+++++ l+++s D+t+ +Wd sp|Q8IWG1|WDR63_HUMAN 505 SGICCQ--------LVTCSADCTICFWD 524 458888........99***********9 PP >> tr|K7ERY9|K7ERY9_HUMAN Echinoderm microtubule-associated protein-like 2 (Fragment) OS=Homo sapiens GN=EML2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.5 0.00015 0.012 2 38 .] 74 121 .. 73 121 .. 0.81 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 0.00015 EEEEEEESS.SSEEEEEEETTSSEEEEE...ET.......TSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG...sd.......DgtvriWd 38 q +r++ GH +++ +la +pd +a+G + ++vriWd tr|K7ERY9|K7ERY9_HUMAN 74 QRQRHYLGHnDDIKCLAIHPDMVTIATGqvaGTtkegkplPPHVRIWD 121 779******666*************99755422457778899999998 PP >> tr|B4DWR9|B4DWR9_HUMAN Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens GN=PPWD1 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.0 0.00069 0.056 14 37 .. 128 151 .. 120 152 .. 0.90 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 0.00069 EEEEEETTSSEEEE.EETTSEEEEE CS WD40 14 tslafspdgawlas.GsdDgtvriW 37 ts++fspdg+ +a+ Gs D++vri+ tr|B4DWR9|B4DWR9_HUMAN 128 TSVCFSPDGKKIATiGS-DRKVRIF 151 89**********95499.*****97 PP >> tr|E5RHM4|E5RHM4_HUMAN DDB1- and CUL4-associated factor 13 OS=Homo sapiens GN=DCAF13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 0.00019 0.015 4 38 .] 55 97 .. 53 97 .. 0.72 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 0.00019 EEEEESS.SSEEEEEEETTSSE.EEEE......ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw.lasG......sdDgtvriWd 38 l +l+GH ++v++la +p++ ++sG +dD+tv+ W+ tr|E5RHM4|E5RHM4_HUMAN 55 LASLDGHrDGVNCLAKHPEKLAtVLSGacdgevGDDKTVKQWK 97 6789***999****865555555667643323336*******6 PP >> tr|K7ELI8|K7ELI8_HUMAN Echinoderm microtubule-associated protein-like 2 (Fragment) OS=Homo sapiens GN=EML2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.2 0.00023 0.019 8 38 .] 70 101 .. 58 101 .. 0.88 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 0.00023 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH ++la++p+ a +++++ D+ v++W+ tr|K7ELI8|K7ELI8_HUMAN 70 QGHvEELWGLATHPSRAQFVTCGQDKLVHLWS 101 5998889************************5 PP >> sp|O15040|TCPR2_HUMAN Tectonin beta-propeller repeat-containing protein 2 OS=Homo sapiens GN=TECPR2 PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 0.0031 0.25 10 34 .. 126 151 .. 115 152 .. 0.87 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 0.0031 S.SSEEEEEEETTSSEEEEEETTSEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtv 34 H +s+t+la+sp+g l+sG+d+g++ sp|O15040|TCPR2_HUMAN 126 HkNSITALAWSPNGMKLFSGDDKGKI 151 9899****************988876 PP >> sp|Q9GZS0|DNAI2_HUMAN Dynein intermediate chain 2, axonemal OS=Homo sapiens GN=DNAI2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.2 7.5 6.1e+02 23 38 .] 278 293 .. 252 293 .. 0.63 2 ? 10.4 0.0 0.058 4.7 3 38 .] 356 392 .. 354 392 .. 0.75 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.5 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 + +s+s Dg v+ Wd sp|Q9GZS0|DNAI2_HUMAN 278 TECFSASTDGQVMWWD 293 33456777*******9 PP == domain 2 score: 10.4 bits; conditional E-value: 0.058 EEEEEESS.SSEEEEE.EETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgaw.lasGsdDgtvriWd 38 + t+ GH +++++l+ + p + +++ + D t riW+ sp|Q9GZS0|DNAI2_HUMAN 356 IVCTFPGHhGPIYALQrN-PFYPKnFLTVG-DWTARIWS 392 67899***999****963.33333456789.*******5 PP >> tr|H0Y8N5|H0Y8N5_HUMAN Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (Fragment) OS=Homo sapiens # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 0.00011 0.0086 14 37 .. 28 51 .. 19 52 .. 0.90 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 0.00011 EEEEEETTSSEEEE.EETTSEEEEE CS WD40 14 tslafspdgawlas.GsdDgtvriW 37 ts++fspdg+ +a+ Gs D++vri+ tr|H0Y8N5|H0Y8N5_HUMAN 28 TSVCFSPDGKKIATiGS-DRKVRIF 51 89**********95499.******7 PP >> sp|A2RUS2-3|DEND3_HUMAN Isoform 3 of DENN domain-containing protein 3 OS=Homo sapiens GN=DENND3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.1 0.00041 0.033 2 38 .] 27 67 .. 26 67 .. 0.78 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 0.00041 EEEEEEESS.SSEEEEE...EETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla...fspdgaw....lasGsdDgtvriWd 38 +c + lt+H ssvt+l + + s+s+Dg v +W+ sp|A2RUS2-3|DEND3_HUMAN 27 SCNKQLTAHcSSVTDLIvqdG----QEapsnVYSCSMDGMVLVWN 67 68999****999****54331....224666789**********8 PP >> tr|C9J471|C9J471_HUMAN WD repeat domain phosphoinositide-interacting protein 4 OS=Homo sapiens GN=WDR45 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.97 79 12 38 .] 8 33 .. 2 33 .. 0.82 2 ? 9.5 0.0 0.12 9.6 6 34 .. 187 216 .. 181 221 .. 0.87 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.97 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +vtsl+f++d++ ++ + + vri++ tr|C9J471|C9J471_HUMAN 8 GVTSLRFNQDQSCFC-CAMETGVRIYN 33 49***********96.55599999997 PP == domain 2 score: 9.5 bits; conditional E-value: 0.12 EEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H s++ +++ ++ g+ +as+s +gt+ tr|C9J471|C9J471_HUMAN 187 TINAHqSDIACVSLNQPGTVVASASQKGTL 216 4569*999*****************88875 PP >> tr|H7C3X9|H7C3X9_HUMAN General transcription factor 3C polypeptide 2 (Fragment) OS=Homo sapiens GN=GTF3C2 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.1 0.00016 0.013 5 38 .] 9 44 .. 5 44 .. 0.71 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 0.00016 EEEESS.SSEEEEEEETTSSE.EE.EEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw.la.sGsdDgtvriWd 38 + + +H + v+ l++++ ++ l+ +Gs D+++++Wd tr|H7C3X9|H7C3X9_HUMAN 9 QCFLAHdQAVRTLQWCKANSHfLVsAGS-DRKIKFWD 44 556689777*999755555555552567.*******9 PP >> tr|J3QRG2|J3QRG2_HUMAN Dynein intermediate chain 2, axonemal OS=Homo sapiens GN=DNAI2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.2 8.5 6.9e+02 23 38 .] 335 350 .. 310 350 .. 0.63 2 ? 10.3 0.0 0.065 5.2 3 38 .] 413 449 .. 411 449 .. 0.75 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.5 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 + +s+s Dg v+ Wd tr|J3QRG2|J3QRG2_HUMAN 335 TECFSASTDGQVMWWD 350 33456777*******9 PP == domain 2 score: 10.3 bits; conditional E-value: 0.065 EEEEEESS.SSEEEEE.EETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgaw.lasGsdDgtvriWd 38 + t+ GH +++++l+ + p + +++ + D t riW+ tr|J3QRG2|J3QRG2_HUMAN 413 IVCTFPGHhGPIYALQrN-PFYPKnFLTVG-DWTARIWS 449 67899***999****963.33333456789.*******5 PP >> sp|Q9H6U6-2|BCAS3_HUMAN Isoform 1 of Breast carcinoma-amplified sequence 3 OS=Homo sapiens GN=BCAS3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.1 0.016 1.3 4 34 .. 344 378 .. 342 380 .. 0.84 2 ? 5.4 0.3 2.2 1.8e+02 8 28 .. 398 423 .. 391 432 .. 0.72 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.016 EEEEESS.SSEEEEEEETTSSEEEE....EETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlas....GsdDgtv 34 + ++ +H ++v+++af+ +g +l++ G+ D +v sp|Q9H6U6-2|BCAS3_HUMAN 344 VAHFPAHeKPVCCMAFNTSGMLLVTtdtlGH-DFHV 378 6799*******************98555556.8776 PP == domain 2 score: 5.4 bits; conditional E-value: 2.2 ESS.SS....EEEEEEETTSSEEEEE CS WD40 8 tGH.ss....vtslafspdgawlasG 28 t H + v +++fs+d +w++ + sp|Q9H6U6-2|BCAS3_HUMAN 398 TLHrGEteakVQDICFSHDCRWVVVS 423 4454224567************9854 PP >> sp|Q9H6U6-3|BCAS3_HUMAN Isoform 3 of Breast carcinoma-amplified sequence 3 OS=Homo sapiens GN=BCAS3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.017 1.4 4 34 .. 344 378 .. 342 380 .. 0.84 2 ? 5.4 0.3 2.3 1.8e+02 8 28 .. 398 423 .. 391 432 .. 0.72 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.017 EEEEESS.SSEEEEEEETTSSEEEE....EETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlas....GsdDgtv 34 + ++ +H ++v+++af+ +g +l++ G+ D +v sp|Q9H6U6-3|BCAS3_HUMAN 344 VAHFPAHeKPVCCMAFNTSGMLLVTtdtlGH-DFHV 378 6799*******************98555556.8776 PP == domain 2 score: 5.4 bits; conditional E-value: 2.3 ESS.SS....EEEEEEETTSSEEEEE CS WD40 8 tGH.ss....vtslafspdgawlasG 28 t H + v +++fs+d +w++ + sp|Q9H6U6-3|BCAS3_HUMAN 398 TLHrGEteakVQDICFSHDCRWVVVS 423 4454224567************9854 PP >> sp|Q9Y2X0-4|MED16_HUMAN Isoform 4 of Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens GN=MED16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.8 7.9e-05 0.0064 7 38 .] 77 109 .. 71 109 .. 0.85 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 7.9e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H +t+l ++++g+ l+s++ Dg ++ W+ sp|Q9Y2X0-4|MED16_HUMAN 77 PSEHhEAITCLEWDQSGSRLLSADADGQIKCWS 109 4567577****************99*******5 PP >> sp|Q9H6U6-7|BCAS3_HUMAN Isoform 5 of Breast carcinoma-amplified sequence 3 OS=Homo sapiens GN=BCAS3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.017 1.4 4 34 .. 344 378 .. 342 380 .. 0.84 2 ? 5.4 0.3 2.2 1.8e+02 8 28 .. 398 423 .. 391 432 .. 0.72 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.017 EEEEESS.SSEEEEEEETTSSEEEE....EETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlas....GsdDgtv 34 + ++ +H ++v+++af+ +g +l++ G+ D +v sp|Q9H6U6-7|BCAS3_HUMAN 344 VAHFPAHeKPVCCMAFNTSGMLLVTtdtlGH-DFHV 378 6799*******************98555556.8776 PP == domain 2 score: 5.4 bits; conditional E-value: 2.2 ESS.SS....EEEEEEETTSSEEEEE CS WD40 8 tGH.ss....vtslafspdgawlasG 28 t H + v +++fs+d +w++ + sp|Q9H6U6-7|BCAS3_HUMAN 398 TLHrGEteakVQDICFSHDCRWVVVS 423 4454224567************9854 PP >> tr|G3V3D6|G3V3D6_HUMAN DDB1- and CUL4-associated factor 4 OS=Homo sapiens GN=DCAF4 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 0.011 0.85 10 38 .] 269 298 .. 262 298 .. 0.91 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.011 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H s vts++ +d ++l+++++ g++++Wd tr|G3V3D6|G3V3D6_HUMAN 269 HdSAVTSVRILQDEQYLMASDMAGKIKLWD 298 9667**************9999*******9 PP >> sp|Q9H6U6|BCAS3_HUMAN Breast carcinoma-amplified sequence 3 OS=Homo sapiens GN=BCAS3 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.017 1.4 4 34 .. 344 378 .. 342 380 .. 0.84 2 ? 5.4 0.3 2.2 1.8e+02 8 28 .. 398 423 .. 391 432 .. 0.72 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.017 EEEEESS.SSEEEEEEETTSSEEEE....EETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlas....GsdDgtv 34 + ++ +H ++v+++af+ +g +l++ G+ D +v sp|Q9H6U6|BCAS3_HUMAN 344 VAHFPAHeKPVCCMAFNTSGMLLVTtdtlGH-DFHV 378 6799*******************98555556.8776 PP == domain 2 score: 5.4 bits; conditional E-value: 2.2 ESS.SS....EEEEEEETTSSEEEEE CS WD40 8 tGH.ss....vtslafspdgawlasG 28 t H + v +++fs+d +w++ + sp|Q9H6U6|BCAS3_HUMAN 398 TLHrGEteakVQDICFSHDCRWVVVS 423 4454224567************9854 PP >> sp|Q9H6U6-8|BCAS3_HUMAN Isoform 4 of Breast carcinoma-amplified sequence 3 OS=Homo sapiens GN=BCAS3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.017 1.4 4 34 .. 344 378 .. 342 380 .. 0.84 2 ? 5.4 0.3 2.3 1.9e+02 8 28 .. 398 423 .. 391 432 .. 0.72 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.017 EEEEESS.SSEEEEEEETTSSEEEE....EETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlas....GsdDgtv 34 + ++ +H ++v+++af+ +g +l++ G+ D +v sp|Q9H6U6-8|BCAS3_HUMAN 344 VAHFPAHeKPVCCMAFNTSGMLLVTtdtlGH-DFHV 378 6799*******************98555556.8776 PP == domain 2 score: 5.4 bits; conditional E-value: 2.3 ESS.SS....EEEEEEETTSSEEEEE CS WD40 8 tGH.ss....vtslafspdgawlasG 28 t H + v +++fs+d +w++ + sp|Q9H6U6-8|BCAS3_HUMAN 398 TLHrGEteakVQDICFSHDCRWVVVS 423 4454224567************9854 PP >> tr|Q5TAQ8|Q5TAQ8_HUMAN DDB1- and CUL4-associated factor 8 (Fragment) OS=Homo sapiens GN=DCAF8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.3 0.00022 0.018 2 29 .. 184 212 .] 183 212 .] 0.91 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 0.00022 EEEEEEESS.SSEEEEEEETTSSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGs 29 ++++ l+GH ++v+ l f++ g+wlasGs tr|Q5TAQ8|Q5TAQ8_HUMAN 184 RLQHGLEGHtGCVNTLHFNQRGTWLASGS 212 57899****777***************98 PP >> tr|B4E039|B4E039_HUMAN DDB1- and CUL4-associated factor 7 OS=Homo sapiens GN=DCAF7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 1.0 0.00052 0.042 4 38 .] 59 95 .. 56 95 .. 0.84 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 0.00052 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 + l H +v+++a+ p+++ ++ ++ dD+ iWd tr|B4E039|B4E039_HUMAN 59 VARLNNHrACVNGIAWAPHSSCHIcTAADDHQALIWD 95 5667889888************7636689*******9 PP >> tr|Q5TBW1|Q5TBW1_HUMAN WD repeat-containing protein WRAP73 (Fragment) OS=Homo sapiens GN=WRAP73 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.27 22 16 29 .. 14 27 .. 4 33 .. 0.80 2 ? 4.1 0.0 5.7 4.6e+02 13 37 .. 51 76 .. 38 77 .. 0.70 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.27 EEEETTSSEEEEEE CS WD40 16 lafspdgawlasGs 29 ++fspdg++las+ tr|Q5TBW1|Q5TBW1_HUMAN 14 CKFSPDGKYLASCV 27 35*********985 PP == domain 2 score: 4.1 bits; conditional E-value: 5.7 EEEEEEETTSSEEEEEE.TTSEEEEE CS WD40 13 vtslafspdgawlasGs.dDgtvriW 37 + ++ +s d+ ++++++ + g v +W tr|Q5TBW1|Q5TBW1_HUMAN 51 IQHIEWSADSLFILCAMyKRGLVQVW 76 66677*********885245555555 PP >> sp|Q9NQW1-4|SC31B_HUMAN Isoform 4 of Protein transport protein Sec31B OS=Homo sapiens GN=SEC31B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.0 0.0082 0.66 10 38 .] 120 150 .. 112 150 .. 0.84 2 ? 6.0 0.0 1.5 1.2e+02 2 34 .. 251 285 .. 250 287 .. 0.73 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.0082 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H + v++l+ ++ g++lasG D + iWd sp|Q9NQW1-4|SC31B_HUMAN 120 HtGAVRALDlNPFQGNLLASGASDSEIFIWD 150 644599999999999999***66*******9 PP == domain 2 score: 6.0 bits; conditional E-value: 1.5 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtv 34 ++l++l+ H ++ s+++s+ a l+++ +D + sp|Q9NQW1-4|SC31B_HUMAN 251 SPLKVLESHsRGILSVSWSQADAElLLTSAKDSQI 285 5899*****555****9665555525688888776 PP >> sp|Q9NQW1-5|SC31B_HUMAN Isoform 5 of Protein transport protein Sec31B OS=Homo sapiens GN=SEC31B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.024 2 10 38 .] 120 150 .. 113 150 .. 0.84 2 ? 4.5 0.0 4.4 3.6e+02 2 34 .. 250 284 .. 249 286 .. 0.73 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.024 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H + v++l+ ++ g++lasG D + iWd sp|Q9NQW1-5|SC31B_HUMAN 120 HtGAVRALDlNPFQGNLLASGASDSEIFIWD 150 644499999999999999***66*******9 PP == domain 2 score: 4.5 bits; conditional E-value: 4.4 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtv 34 ++l++l+ H ++ s+++s+ a l+++ +D + sp|Q9NQW1-5|SC31B_HUMAN 250 SPLKVLESHsRGILSVSWSQADAElLLTSAKDSQI 284 5899*****555****9665555525688888776 PP >> sp|Q9NQW1|SC31B_HUMAN Protein transport protein Sec31B OS=Homo sapiens GN=SEC31B PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.024 2 10 38 .] 120 150 .. 113 150 .. 0.84 2 ? 4.5 0.0 4.4 3.6e+02 2 34 .. 251 285 .. 250 287 .. 0.73 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.024 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H + v++l+ ++ g++lasG D + iWd sp|Q9NQW1|SC31B_HUMAN 120 HtGAVRALDlNPFQGNLLASGASDSEIFIWD 150 644499999999999999***66*******9 PP == domain 2 score: 4.5 bits; conditional E-value: 4.4 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtv 34 ++l++l+ H ++ s+++s+ a l+++ +D + sp|Q9NQW1|SC31B_HUMAN 251 SPLKVLESHsRGILSVSWSQADAElLLTSAKDSQI 285 5899*****555****9665555525688888776 PP >> sp|O15040-2|TCPR2_HUMAN Isoform 2 of Tectonin beta-propeller repeat-containing protein 2 OS=Homo sapiens GN=TECPR2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 0.0027 0.22 10 34 .. 126 151 .. 115 152 .. 0.87 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.0027 S.SSEEEEEEETTSSEEEEEETTSEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtv 34 H +s+t+la+sp+g l+sG+d+g++ sp|O15040-2|TCPR2_HUMAN 126 HkNSITALAWSPNGMKLFSGDDKGKI 151 9899****************988876 PP >> tr|H0YM76|H0YM76_HUMAN WD repeat-containing protein 61 OS=Homo sapiens GN=WDR61 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 18.5 0.1 0.00016 0.013 9 38 .] 14 48 .] 5 48 .] 0.79 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 0.00016 SS.SSEEEEEEETTSSE..........EEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..........lasGsdDgtvriWd 38 +H + ++s+a w +++Gs D v++W+ tr|H0YM76|H0YM76_HUMAN 14 AHdDAIWSVA------WgtnkkensetVVTGSLDDLVKVWK 48 89555****5......5555555999999***********6 PP >> tr|H0YFZ7|H0YFZ7_HUMAN Autophagy-related protein 16-2 (Fragment) OS=Homo sapiens GN=ATG16L2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 18.3 0.0 0.00019 0.015 5 38 .] 65 98 .. 56 98 .. 0.81 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 0.00019 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 +++ ++ vtsl+ s+d+ l+s+s+D+t+++ d tr|H0YFZ7|H0YFZ7_HUMAN 65 QVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVID 98 44444444***********************965 PP >> tr|H7C5M3|H7C5M3_HUMAN Intraflagellar transport protein 80 homolog (Fragment) OS=Homo sapiens GN=IFT80 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.045 3.7 25 38 .] 6 19 .. 2 19 .. 0.75 2 ? 6.4 0.0 1.1 88 9 25 .. 30 47 .. 22 54 .. 0.74 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.045 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 l++ ++Dg ++iW+ tr|H7C5M3|H7C5M3_HUMAN 6 LVTVGEDGQIKIWS 19 455667*******6 PP == domain 2 score: 6.4 bits; conditional E-value: 1.1 SS.SSEEEEEEETTSSEE CS WD40 9 GH.ssvtslafspdgawl 25 + ++v+s+a+ pd+ + tr|H7C5M3|H7C5M3_HUMAN 30 QQgTPVYSVAWGPDSEKV 47 34457*********9765 PP >> sp|Q9UFC0|LRWD1_HUMAN Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens GN=LRWD1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.1 0.0014 0.11 3 38 .] 384 421 .. 382 421 .. 0.88 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 0.0014 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 c +++++H + + l+fsp + l+++s+D+ + +Wd sp|Q9UFC0|LRWD1_HUMAN 384 CCGVIRAHkKAIATLCFSPAHEThLFTASYDKRIILWD 421 778899**888************4459999*******9 PP >> tr|C9JD14|C9JD14_HUMAN Guanine nucleotide-binding protein subunit beta-4 (Fragment) OS=Homo sapiens GN=GNB4 PE=2 SV= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 18.1 0.0 0.00022 0.018 4 34 .. 48 79 .] 45 79 .] 0.91 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 0.00022 EEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtv 34 rtl+GH ++++ + d+++l+s+s Dg++ tr|C9JD14|C9JD14_HUMAN 48 RRTLRGHlAKIYAMHWGYDSRLLVSASQDGKL 79 699****999*******************975 PP >> tr|F8WE20|F8WE20_HUMAN WD repeat-containing protein 75 OS=Homo sapiens GN=WDR75 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.1 0.0057 0.46 2 24 .. 48 71 .. 47 81 .. 0.88 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 0.0057 EEEEEEESS.SSEEEEEEETTSSE CS WD40 2 qclrtltGH.ssvtslafspdgaw 24 +c+++l GH + vt+++ +p++++ tr|F8WE20|F8WE20_HUMAN 48 ECVHILHGHrNLVTGIQLNPNNHL 71 8********777****99999875 PP >> sp|Q8WV16-2|DCAF4_HUMAN Isoform 2 of DDB1- and CUL4-associated factor 4 OS=Homo sapiens GN=DCAF4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 0.015 1.2 10 38 .] 369 398 .. 362 398 .. 0.91 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.015 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H s vts++ +d ++l+++++ g++++Wd sp|Q8WV16-2|DCAF4_HUMAN 369 HdSAVTSVRILQDEQYLMASDMAGKIKLWD 398 9667**************9999*******9 PP >> tr|E9PDG2|E9PDG2_HUMAN Intraflagellar transport protein 122 homolog OS=Homo sapiens GN=IFT122 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.038 3.1 7 37 .. 108 139 .. 102 140 .. 0.79 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.038 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 + s+v+ ++ pd+++++ G+ Dgt+ ++ tr|E9PDG2|E9PDG2_HUMAN 108 VGEQnSWVWTCQAKPDSNYVVVGCQDGTISFY 139 444545698888*****************876 PP >> tr|B9A049|B9A049_HUMAN WD repeat-containing protein 54 OS=Homo sapiens GN=WDR54 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.0 0.23 18 8 38 .] 197 228 .. 190 228 .. 0.67 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.23 ESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +H +++l+ s g++l s+++D v+iW+ tr|B9A049|B9A049_HUMAN 197 NAHaRAICALDlASEVGKLL-SAGEDTFVHIWK 228 57855599995444445555.6777*******6 PP >> tr|C9JUJ1|C9JUJ1_HUMAN Intraflagellar transport protein 80 homolog (Fragment) OS=Homo sapiens GN=IFT80 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 1 84 10 29 .. 9 30 .. 2 36 .. 0.72 2 ? 9.8 0.0 0.091 7.3 6 33 .. 46 74 .. 41 77 .] 0.81 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 1 S.SSEEEEEEETTSSEEE.EEE CS WD40 10 H.ssvtslafspdgawla.sGs 29 + ++v+s+a+ pd+ ++ +++ tr|C9JUJ1|C9JUJ1_HUMAN 9 QgTPVYSVAWGPDSEKVLyTAG 30 3457*********998654655 PP == domain 2 score: 9.8 bits; conditional E-value: 0.091 EEESSSS.EEEEEEETTSSEEEEEETTSE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgt 33 +++H++ + +++++ +++++s+++D++ tr|C9JUJ1|C9JUJ1_HUMAN 46 QWKAHDGiILKVDWNSVNDLILSAGEDCK 74 5689*55479************9999985 PP >> tr|F8WC81|F8WC81_HUMAN WD repeat-containing protein 75 OS=Homo sapiens GN=WDR75 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.1 0.0072 0.59 2 23 .. 48 70 .. 47 81 .. 0.88 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 0.0072 EEEEEEESS.SSEEEEEEETTSS CS WD40 2 qclrtltGH.ssvtslafspdga 23 +c+++l GH + vt+++ +p+++ tr|F8WC81|F8WC81_HUMAN 48 ECVHILHGHrNLVTGIQLNPNNH 70 8********777****9999986 PP >> sp|Q92466-5|DDB2_HUMAN Isoform D4 of DNA damage-binding protein 2 OS=Homo sapiens GN=DDB2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.0 0.09 7.3 14 38 .] 115 140 .. 101 140 .. 0.93 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.09 EEEEEETTSSE.EEEEETTSEEEEEE CS WD40 14 tslafspdgaw.lasGsdDgtvriWd 38 tsla++p ++ +a Gs+ g +++W+ sp|Q92466-5|DDB2_HUMAN 115 TSLAWHPTHPStVAVGSKGGDIMLWN 140 89*9******99889**********8 PP >> tr|H0YA17|H0YA17_HUMAN Lipopolysaccharide-responsive and beige-like anchor protein (Fragment) OS=Homo sapiens GN=LRB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.1 2 1.6e+02 24 37 .. 2 15 .. 1 16 [. 0.92 2 ? 8.9 0.1 0.17 14 5 29 .. 37 62 .. 34 132 .. 0.92 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 2 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 +++sGs+D t+ +W tr|H0YA17|H0YA17_HUMAN 2 YILSGSRDATLLLW 15 688*********** PP == domain 2 score: 8.9 bits; conditional E-value: 0.17 EEEESSSS.EEEEEEETTSSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGs 29 +ltGH+ vt+ a++ + +++sGs tr|H0YA17|H0YA17_HUMAN 37 AILTGHDYeVTCAAVCAELGLVLSGS 62 689***447****9888888888888 PP >> tr|H7C5P3|H7C5P3_HUMAN Intraflagellar transport protein 80 homolog (Fragment) OS=Homo sapiens GN=IFT80 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 17.2 0.0 0.00041 0.033 10 29 .. 19 39 .. 10 49 .. 0.76 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 0.00041 S.SSEEEEEEETTSSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGs 29 H ++ts+a+ pdg ++a Gs tr|H7C5P3|H7C5P3_HUMAN 19 HeHPITSVAWAPDGELFAVGS 39 5338**************998 PP >> tr|H3BNC5|H3BNC5_HUMAN Intraflagellar transport protein 140 homolog (Fragment) OS=Homo sapiens GN=IFT140 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.025 2.1 4 28 .. 95 121 .] 92 121 .] 0.81 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.025 EEEEE.SS.SSEEEEEEETTSSEEEEE CS WD40 4 lrtlt.GH.ssvtslafspdgawlasG 28 ++t +H ++t l++sp+g+ l+sG tr|H3BNC5|H3BNC5_HUMAN 95 QHTMPlTHtADITVLRWSPSGNCLLSG 121 55544479888*************998 PP >> tr|E5RG45|E5RG45_HUMAN TBC1 domain family member 31 (Fragment) OS=Homo sapiens GN=TBC1D31 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.2 0.0015 0.12 8 38 .] 2 32 .. 1 32 [. 0.91 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 0.0015 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH ssv s++++ +g++ ++ s t +Wd tr|E5RG45|E5RG45_HUMAN 2 RGHeSSVFSISVHASGKYAITTS-SDTAQLWD 32 7**999************99999.88888887 PP >> sp|Q9BSC4-3|NOL10_HUMAN Isoform 3 of Nucleolar protein 10 OS=Homo sapiens GN=NOL10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 8.6 6.9e+02 11 38 .] 35 54 .. 20 54 .. 0.77 2 ? 8.8 0.0 0.19 15 10 38 .] 119 149 .. 112 149 .. 0.82 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 8.6 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 +sv++l +a+G+ g v Wd sp|Q9BSC4-3|NOL10_HUMAN 35 NSVHGL--------FATGTIEGRVECWD 54 235555........799**********9 PP == domain 2 score: 8.8 bits; conditional E-value: 0.19 SSS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss...vtslafspdgawlasGsdDgtvriWd 38 H+ + s+ f+++ ++++s++ + v++W+ sp|Q9BSC4-3|NOL10_HUMAN 119 HQYglpIKSVHFQDSLDLILSAD-SRIVKMWN 149 52235599999*********888.*******8 PP >> tr|C9J5L0|C9J5L0_HUMAN WD repeat domain phosphoinositide-interacting protein 4 (Fragment) OS=Homo sapiens GN=WDR45 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.0 0.4 32 12 38 .] 8 33 .. 2 33 .. 0.82 2 ? 4.2 0.1 5.3 4.3e+02 6 27 .. 120 142 .. 116 143 .] 0.82 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.4 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +vtsl+f++d++ ++ + + vri++ tr|C9J5L0|C9J5L0_HUMAN 8 GVTSLRFNQDQSCFC-CAMETGVRIYN 33 49***********96.55599999997 PP == domain 2 score: 4.2 bits; conditional E-value: 5.3 EEESS.SSEEEEEEETTSSEEEE CS WD40 6 tltGH.ssvtslafspdgawlas 27 t+ +H s++ +++ ++ g+ +as tr|C9J5L0|C9J5L0_HUMAN 120 TINAHqSDIACVSLNQPGTVVAS 142 5569*999****99999988876 PP >> tr|H3BQ74|H3BQ74_HUMAN Target of rapamycin complex subunit LST8 (Fragment) OS=Homo sapiens GN=MLST8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 0.0045 0.36 24 37 .. 14 27 .. 6 28 .. 0.82 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.0045 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 la++++D+tvr+W tr|H3BQ74|H3BQ74_HUMAN 14 ILATAGYDHTVRFW 27 5888888******* PP >> sp|Q9H967|WDR76_HUMAN WD repeat-containing protein 76 OS=Homo sapiens GN=WDR76 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.5 41 4 35 .. 353 386 .. 350 387 .. 0.78 2 ? 8.0 0.0 0.35 28 2 38 .] 486 524 .. 485 524 .. 0.74 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.5 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvr 35 ++++ H ++v++l fsp ++ ++ s s+Dgt+r sp|Q9H967|WDR76_HUMAN 353 VYVFHPHsQPVSCLYFSPANPAHIlSLSYDGTLR 386 5677788777*****99999995425588**998 PP == domain 2 score: 8.0 bits; conditional E-value: 0.35 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 q+l +lt H +s+ s fsp ++++ D+++ri+d sp|Q9H967|WDR76_HUMAN 486 QPLISLTEHtKSIASAYFSPLTGNrvVTTCA-DCNLRIFD 524 7899999**9999777655555556355666.******98 PP >> tr|K7ER35|K7ER35_HUMAN Elongator complex protein 2 OS=Homo sapiens GN=ELP2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 17.2 0.5 0.00042 0.034 4 37 .. 51 90 .. 48 91 .. 0.71 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 0.00042 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 ++ l GH v++++ sp+ ++ sG+ D+ v W tr|K7ER35|K7ER35_HUMAN 51 VTNLNGHtARVNCIQwickqdGSPSTELV-SGGSDNQVIHW 90 56789**6669999555555566666665.6766**99998 PP >> tr|J3QLD6|J3QLD6_HUMAN U3 small nucleolar RNA-associated protein 18 homolog (Fragment) OS=Homo sapiens GN=UTP18 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.039 3.2 15 38 .] 21 44 .. 5 44 .. 0.82 2 ? 4.4 0.0 4.7 3.8e+02 12 29 .. 66 83 .. 52 92 .. 0.85 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.039 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 s+a+s++g+++a+Gs g v i++ tr|J3QLD6|J3QLD6_HUMAN 21 SIATSRNGQYVACGSNCGVVNIYN 44 678************888888886 PP == domain 2 score: 4.4 bits; conditional E-value: 4.7 SEEEEEEETTSSEEEEEE CS WD40 12 svtslafspdgawlasGs 29 +vtsl f+p la +s tr|J3QLD6|J3QLD6_HUMAN 66 GVTSLTFNPTTEILAIAS 83 599********9999777 PP >> sp|Q5MNZ9-2|WIPI1_HUMAN Isoform 2 of WD repeat domain phosphoinositide-interacting protein 1 OS=Homo sapiens GN=WIPI # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 1.5 1.2e+02 5 34 .. 175 205 .. 166 206 .. 0.79 2 ? 4.3 0.0 5.1 4.1e+02 13 34 .. 230 251 .. 214 255 .. 0.73 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 1.5 EEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H + ++ f+ +g+ las+s++gtv sp|Q5MNZ9-2|WIPI1_HUMAN 175 CTIAAHeGTLAAITFNASGSKLASASEKGTV 205 44557766678888***************98 PP == domain 2 score: 4.3 bits; conditional E-value: 5.1 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 ++sl fs d+++l+++s tv sp|Q5MNZ9-2|WIPI1_HUMAN 230 ISSLVFSMDSQFLCASSNTETV 251 88999********988855555 PP >> sp|Q9GZS0-2|DNAI2_HUMAN Isoform 2 of Dynein intermediate chain 2, axonemal OS=Homo sapiens GN=DNAI2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.2 7.3 5.9e+02 23 38 .] 278 293 .. 252 293 .. 0.63 2 ? 10.5 0.0 0.057 4.6 3 38 .] 356 392 .. 354 392 .. 0.75 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 7.3 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 + +s+s Dg v+ Wd sp|Q9GZS0-2|DNAI2_HUMAN 278 TECFSASTDGQVMWWD 293 33456777*******9 PP == domain 2 score: 10.5 bits; conditional E-value: 0.057 EEEEEESS.SSEEEEE.EETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgaw.lasGsdDgtvriWd 38 + t+ GH +++++l+ + p + +++ + D t riW+ sp|Q9GZS0-2|DNAI2_HUMAN 356 IVCTFPGHhGPIYALQrN-PFYPKnFLTVG-DWTARIWS 392 67899***999****963.33333456789.*******5 PP >> sp|Q5MNZ9|WIPI1_HUMAN WD repeat domain phosphoinositide-interacting protein 1 OS=Homo sapiens GN=WIPI1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 1.6 1.3e+02 5 34 .. 180 210 .. 172 211 .. 0.81 2 ? 4.3 0.0 5.2 4.2e+02 13 34 .. 235 256 .. 219 260 .. 0.73 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 1.6 EEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H + ++ f+ +g+ las+s++gtv sp|Q5MNZ9|WIPI1_HUMAN 180 CTIAAHeGTLAAITFNASGSKLASASEKGTV 210 44557866688899***************98 PP == domain 2 score: 4.3 bits; conditional E-value: 5.2 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 ++sl fs d+++l+++s tv sp|Q5MNZ9|WIPI1_HUMAN 235 ISSLVFSMDSQFLCASSNTETV 256 88999********988855555 PP >> tr|D6RCF7|D6RCF7_HUMAN WD repeat-containing protein 19 OS=Homo sapiens GN=WDR19 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.42 34 21 38 .] 25 42 .. 18 42 .. 0.85 2 ? 7.6 0.1 0.45 37 14 38 .] 56 83 .. 44 83 .. 0.77 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.42 TSSEEE.EEETTSEEEEEE CS WD40 21 dgawla.sGsdDgtvriWd 38 +g++la +G D v+i+d tr|D6RCF7|D6RCF7_HUMAN 25 SGNYLAvTGA-DYIVKIFD 42 6899974777.******98 PP == domain 2 score: 7.6 bits; conditional E-value: 0.45 EEEE..EETTSSEEE.EEETTSEEEEEE CS WD40 14 tsla..fspdgawla.sGsdDgtvriWd 38 +++a +++dg+ la + + +++Wd tr|D6RCF7|D6RCF7_HUMAN 56 NCVAmdWDKDGDVLAvIAEKSSCIYLWD 83 345555*******974688899999998 PP >> tr|K7EIM1|K7EIM1_HUMAN Echinoderm microtubule-associated protein-like 2 (Fragment) OS=Homo sapiens GN=EML2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.2 0.0 0.0009 0.073 2 28 .. 74 101 .. 73 107 .. 0.88 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 0.0009 EEEEEEESS.SSEEEEEEETTSSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasG 28 q +r++ GH +++ +la +pd +a+G tr|K7EIM1|K7EIM1_HUMAN 74 QRQRHYLGHnDDIKCLAIHPDMVTIATG 101 779******666*********9999987 PP >> tr|D6RBA0|D6RBA0_HUMAN WD repeat-containing protein 19 OS=Homo sapiens GN=WDR19 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.43 35 21 38 .] 25 42 .. 18 42 .. 0.85 2 ? 7.6 0.1 0.46 38 14 38 .] 56 83 .. 44 83 .. 0.77 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.43 TSSEEE.EEETTSEEEEEE CS WD40 21 dgawla.sGsdDgtvriWd 38 +g++la +G D v+i+d tr|D6RBA0|D6RBA0_HUMAN 25 SGNYLAvTGA-DYIVKIFD 42 6899974777.******98 PP == domain 2 score: 7.6 bits; conditional E-value: 0.46 EEEE..EETTSSEEE.EEETTSEEEEEE CS WD40 14 tsla..fspdgawla.sGsdDgtvriWd 38 +++a +++dg+ la + + +++Wd tr|D6RBA0|D6RBA0_HUMAN 56 NCVAmdWDKDGDVLAvIAEKSSCIYLWD 83 345555*******974688899999998 PP >> tr|K7EJH7|K7EJH7_HUMAN Breast carcinoma-amplified sequence 3 (Fragment) OS=Homo sapiens GN=BCAS3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.3 0.0018 0.15 4 34 .. 115 149 .. 113 167 .. 0.89 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.0018 EEEEESS.SSEEEEEEETTSSEEEE....EETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlas....GsdDgtv 34 + ++ +H ++v+++af+ +g +l++ G+ D +v tr|K7EJH7|K7EJH7_HUMAN 115 VAHFPAHeKPVCCMAFNTSGMLLVTtdtlGH-DFHV 149 6799*******************98555556.8777 PP >> tr|F5GYE9|F5GYE9_HUMAN Elongator complex protein 2 OS=Homo sapiens GN=ELP2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.7 0.5 0.0006 0.049 4 37 .. 51 90 .. 48 91 .. 0.71 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 0.0006 EEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 ++ l GH v++++ sp+ ++ sG+ D+ v W tr|F5GYE9|F5GYE9_HUMAN 51 VTNLNGHtARVNCIQwickqdGSPSTELV-SGGSDNQVIHW 90 56789**6669999555555566666665.6766**99998 PP >> tr|K7EK57|K7EK57_HUMAN WD repeat domain phosphoinositide-interacting protein 1 OS=Homo sapiens GN=WIPI1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 1.2 93 5 34 .. 180 210 .. 171 211 .. 0.79 2 ? 4.6 0.0 4.1 3.3e+02 13 34 .. 235 256 .. 219 260 .. 0.73 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 1.2 EEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H + ++ f+ +g+ las+s++gtv tr|K7EK57|K7EK57_HUMAN 180 CTIAAHeGTLAAITFNASGSKLASASEKGTV 210 44557766678888***************98 PP == domain 2 score: 4.6 bits; conditional E-value: 4.1 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 ++sl fs d+++l+++s tv tr|K7EK57|K7EK57_HUMAN 235 ISSLVFSMDSQFLCASSNTETV 256 88999********988855555 PP >> tr|K7EML5|K7EML5_HUMAN Breast carcinoma-amplified sequence 3 (Fragment) OS=Homo sapiens GN=BCAS3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.1 0.0018 0.15 4 34 .. 115 149 .. 113 152 .. 0.85 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.0018 EEEEESS.SSEEEEEEETTSSEEEE....EETTSEE CS WD40 4 lrtltGH.ssvtslafspdgawlas....GsdDgtv 34 + ++ +H ++v+++af+ +g +l++ G+ D +v tr|K7EML5|K7EML5_HUMAN 115 VAHFPAHeKPVCCMAFNTSGMLLVTtdtlGH-DFHV 149 6799*******************98555566.8777 PP >> tr|H0YCY3|H0YCY3_HUMAN TBC1 domain family member 31 (Fragment) OS=Homo sapiens GN=TBC1D31 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.19 15 18 37 .. 26 45 .. 14 46 .. 0.88 2 ? 4.6 0.0 4.2 3.4e+02 13 37 .. 113 137 .. 99 138 .. 0.75 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.19 EETTSSEEEEEETTSEEEEE CS WD40 18 fspdgawlasGsdDgtvriW 37 + +dg+ la+G++ +++++W tr|H0YCY3|H0YCY3_HUMAN 26 VTRDGRILAAGGKSNHLHLW 45 5899**************** PP == domain 2 score: 4.6 bits; conditional E-value: 4.2 EEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 13 vtslafspdgawlasG.sdDgtvriW 37 ++s a sp+g+++a + +++g++ i+ tr|H0YCY3|H0YCY3_HUMAN 113 ISSSAISPHGRYIA-SiMENGSLNIY 137 556669******98.44888888887 PP >> tr|D6RGJ8|D6RGJ8_HUMAN WD repeat-containing protein 55 OS=Homo sapiens GN=WDR55 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 0.048 3.9 15 37 .. 43 65 .. 36 66 .. 0.91 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.048 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 +laf+p ++la+G+ Dg v ++ tr|D6RGJ8|D6RGJ8_HUMAN 43 GLAFHPARDLLAAGDVDGDVFVF 65 799***********99***9886 PP >> tr|D6RE64|D6RE64_HUMAN Protein transport protein Sec31A (Fragment) OS=Homo sapiens GN=SEC31A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 1.6 1.3e+02 12 38 .] 84 102 .. 59 102 .. 0.85 2 ? 7.0 0.0 0.71 58 10 38 .] 121 151 .. 112 151 .. 0.75 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 1.6 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v+++ l++G+++g++ ++d tr|D6RE64|D6RE64_HUMAN 84 DVSGV--------LIAGGENGNIILYD 102 47788........999*******9998 PP == domain 2 score: 7.0 bits; conditional E-value: 0.71 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H ++v++l+ + +++asG ++iWd tr|D6RE64|D6RE64_HUMAN 121 HtGPVRALDvNIFQTNLVASGANESEIYIWD 151 75668888744444455789989*******9 PP >> tr|D6RCQ9|D6RCQ9_HUMAN Protein transport protein Sec31A (Fragment) OS=Homo sapiens GN=SEC31A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 1.6 1.3e+02 12 38 .] 84 102 .. 59 102 .. 0.85 2 ? 7.0 0.0 0.72 58 10 38 .] 121 151 .. 112 151 .. 0.75 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 1.6 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v+++ l++G+++g++ ++d tr|D6RCQ9|D6RCQ9_HUMAN 84 DVSGV--------LIAGGENGNIILYD 102 47788........999*******9998 PP == domain 2 score: 7.0 bits; conditional E-value: 0.72 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 H ++v++l+ + +++asG ++iWd tr|D6RCQ9|D6RCQ9_HUMAN 121 HtGPVRALDvNIFQTNLVASGANESEIYIWD 151 75668888744444455789989*******9 PP >> tr|A3KFI9|A3KFI9_HUMAN Cleavage stimulation factor subunit 1 (Fragment) OS=Homo sapiens GN=CSTF1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.0 0.0019 0.15 8 36 .. 105 134 .. 98 136 .. 0.82 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 0.0019 ESSSSEEEEE.EETTSSEEEEEETTSEEEE CS WD40 8 tGHssvtsla.fspdgawlasGsdDgtvri 36 t H++ + +a +s+dg+++a+Gs D +++i tr|A3KFI9|A3KFI9_HUMAN 105 TSHKGPCRVAtYSRDGQLIATGSADASIKI 134 467555677789*****************9 PP >> tr|K7EL23|K7EL23_HUMAN Echinoderm microtubule-associated protein-like 2 (Fragment) OS=Homo sapiens GN=EML2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.8 0.4 0.0011 0.093 4 31 .. 8 36 .. 5 41 .. 0.79 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 0.0011 EEEEESS.SSEEEEEEETTSSEEEEEETT CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdD 31 l++++GH s++t+l++ +d++ +++ s D tr|K7EL23|K7EL23_HUMAN 8 LGKCSGHsSFITHLDWAQDSSCFVTNSGD 36 67899**777***********99863336 PP >> tr|H7C1Z3|H7C1Z3_HUMAN Nucleolar protein 10 (Fragment) OS=Homo sapiens GN=NOL10 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.28 22 10 38 .] 160 190 .. 153 190 .. 0.82 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.28 SSS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss...vtslafspdgawlasGsdDgtvriWd 38 H+ + s+ f+++ ++++s++ + v++W+ tr|H7C1Z3|H7C1Z3_HUMAN 160 HQYglpIKSVHFQDSLDLILSAD-SRIVKMWN 190 52235599999*********888.*******8 PP >> tr|F8W7Y5|F8W7Y5_HUMAN WD repeat-containing protein 48 OS=Homo sapiens GN=WDR48 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 0.0014 0.11 11 38 .] 31 58 .. 23 58 .. 0.89 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 0.0014 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v++l+ +p + l+++++D +riW+ tr|F8W7Y5|F8W7Y5_HUMAN 31 NGVNALQLDPALNRLFTAGRDSIIRIWS 58 56999999999999**9999*******6 PP >> tr|G5EA37|G5EA37_HUMAN WD repeat domain phosphoinositide-interacting protein 1 OS=Homo sapiens GN=WIPI1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 1.1 92 5 34 .. 98 128 .. 89 129 .. 0.79 2 ? 4.6 0.0 4 3.2e+02 13 34 .. 153 174 .. 137 178 .. 0.73 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 1.1 EEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtv 34 t+ +H + ++ f+ +g+ las+s++gtv tr|G5EA37|G5EA37_HUMAN 98 CTIAAHeGTLAAITFNASGSKLASASEKGTV 128 44557766678888***************98 PP == domain 2 score: 4.6 bits; conditional E-value: 4 EEEEEEETTSSEEEEEETTSEE CS WD40 13 vtslafspdgawlasGsdDgtv 34 ++sl fs d+++l+++s tv tr|G5EA37|G5EA37_HUMAN 153 ISSLVFSMDSQFLCASSNTETV 174 88999********988855555 PP >> tr|H7C0C5|H7C0C5_HUMAN THO complex subunit 3 (Fragment) OS=Homo sapiens GN=THOC3 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.1 0.0013 0.11 12 34 .. 22 44 .. 10 45 .. 0.80 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 0.0013 SEEEEEEETTSSEEEEEETTSEE CS WD40 12 svtslafspdgawlasGsdDgtv 34 +v+ l+fs+dg++las+s+D+ + tr|H7C0C5|H7C0C5_HUMAN 22 PVRTLSFSHDGKMLASASEDHFI 44 389999**************965 PP >> tr|F8VZB3|F8VZB3_HUMAN Protein POC1B-GALNT4 OS=Homo sapiens GN=POC1B-GALNT4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 0.0 0.0013 0.1 6 25 .. 13 33 .. 6 39 .. 0.83 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 0.0013 EEESS.SSEEEEEEETTSSEE CS WD40 6 tltGH.ssvtslafspdgawl 25 ++GH +tsl+ sp+g+ l tr|F8VZB3|F8VZB3_HUMAN 13 YFKGHkAAITSLDLSPNGKQL 33 589**666**********875 PP >> tr|Q5TDQ5|Q5TDQ5_HUMAN Peroxisomal targeting signal 2 receptor OS=Homo sapiens GN=PEX7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.6 0.0033 0.26 12 38 .] 69 96 .. 58 96 .. 0.75 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 0.0033 SEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 12 svtslafspdgawla.sGsdDgtvriWd 38 + ++ +s ++ ++ ++s Dg++ +Wd tr|Q5TDQ5|Q5TDQ5_HUMAN 69 GLFDVTWSENNEHVLiTCSGDGSLQLWD 96 46789999999996448877*******9 PP >> sp|Q6P1M3-3|L2GL2_HUMAN Isoform B of Lethal(2) giant larvae protein homolog 2 OS=Homo sapiens GN=LLGL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 1.0 0.41 33 17 34 .. 229 254 .. 191 257 .. 0.74 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.41 E........EETTSSEEEEEETTSEE CS WD40 17 a........fspdgawlasGsdDgtv 34 + +++dg++l+s++ Dg+ sp|Q6P1M3-3|L2GL2_HUMAN 229 SsqqleniwWQRDGRLLVSCHSDGSY 254 033355555***********88*985 PP >> tr|F8W6P2|F8W6P2_HUMAN WD repeat-containing protein 48 OS=Homo sapiens GN=WDR48 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.0 0.002 0.16 11 38 .] 31 58 .. 23 58 .. 0.89 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 0.002 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v++l+ +p + l+++++D +riW+ tr|F8W6P2|F8W6P2_HUMAN 31 NGVNALQLDPALNRLFTAGRDSIIRIWS 58 56999999999999**9999*******6 PP >> sp|Q96RY7|IF140_HUMAN Intraflagellar transport protein 140 homolog OS=Homo sapiens GN=IFT140 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.035 2.8 4 37 .. 95 130 .. 92 131 .. 0.80 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.035 EEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtlt.GH.ssvtslafspdgawlasGsdDgtvriW 37 ++t +H ++t l++sp+g+ l+sG++ g + +W sp|Q96RY7|IF140_HUMAN 95 QHTMPlTHtADITVLRWSPSGNCLLSGDRLGVLLLW 130 55543479888***************9888888888 PP >> tr|E5RI27|E5RI27_HUMAN TBC1 domain family member 31 (Fragment) OS=Homo sapiens GN=TBC1D31 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.1 0.0017 0.14 7 31 .. 17 42 .. 9 44 .] 0.80 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 0.0017 EESS.SSEEEEEEETTSSEEEEEETT CS WD40 7 ltGH.ssvtslafspdgawlasGsdD 31 +GH ssv s++++ +g++ ++ s D tr|E5RI27|E5RI27_HUMAN 17 MRGHeSSVFSISVHASGKYAITTSSD 42 48**999************7655437 PP >> tr|F8VV91|F8VV91_HUMAN POC1 centriolar protein homolog B OS=Homo sapiens GN=POC1B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.0 0.0017 0.14 6 25 .. 13 33 .. 2 43 .. 0.85 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 0.0017 EEESS.SSEEEEEEETTSSEE CS WD40 6 tltGH.ssvtslafspdgawl 25 ++GH +tsl+ sp+g+ l tr|F8VV91|F8VV91_HUMAN 13 YFKGHkAAITSLDLSPNGKQL 33 589**666**********875 PP >> sp|Q9NXC5-2|MIO_HUMAN Isoform 2 of WD repeat-containing protein mio OS=Homo sapiens GN=MIOS # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.2 0.24 19 21 38 .] 125 146 .. 110 146 .. 0.80 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.24 TSSEEEEEET....TSEEEEEE CS WD40 21 dgawlasGsd....DgtvriWd 38 d++wla+G d D +v iWd sp|Q9NXC5-2|MIO_HUMAN 125 DSNWLAAGLDkhraDFSVLIWD 146 89*****9433556*******9 PP >> tr|F5GY56|F5GY56_HUMAN Pre-mRNA-processing factor 19 (Fragment) OS=Homo sapiens GN=PRPF19 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.1 0.0036 0.29 13 38 .] 224 250 .. 208 250 .. 0.67 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 0.0036 EEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 13 vtsla..fspdgawlasGsdDgtvriWd 38 + +l+ s+ ++ ++G++D ++iWd tr|F5GY56|F5GY56_HUMAN 224 ILALDlcPSDTNKI-LTGTMDSQIKIWD 250 54444315555555.58*99*******9 PP >> tr|K7EKB0|K7EKB0_HUMAN Breast carcinoma-amplified sequence 3 (Fragment) OS=Homo sapiens GN=BCAS3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 0.0078 0.63 4 27 .. 115 139 .. 112 144 .. 0.89 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 0.0078 EEEEESS.SSEEEEEEETTSSEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlas 27 + ++ +H ++v+++af+ +g +l++ tr|K7EKB0|K7EKB0_HUMAN 115 VAHFPAHeKPVCCMAFNTSGMLLVT 139 6799*****************9987 PP >> sp|Q9NRJ4-2|TULP4_HUMAN Isoform 2 of Tubby-related protein 4 OS=Homo sapiens GN=TULP4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.0 0.39 31 6 37 .. 77 109 .. 71 109 .. 0.83 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.39 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 l+GH s v ++++ + la+++ Dg + +W sp|Q9NRJ4-2|TULP4_HUMAN 77 NLRGHnSEVVLVRWNEPYQKLATCDADGGIFVW 109 589**5559899888888889***99******* PP >> tr|H7BXC4|H7BXC4_HUMAN Syntaxin binding protein 5 (Tomosyn), isoform CRA_e OS=Homo sapiens GN=STXBP5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.4 0.019 1.5 22 38 .] 109 135 .. 57 135 .. 0.61 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.019 SSE..........EEEEETTSEEEEEE CS WD40 22 gaw..........lasGsdDgtvriWd 38 g+w +++G+ Dg+v++Wd tr|H7BXC4|H7BXC4_HUMAN 109 GNWglgaqsypeiIITGHADGSVKFWD 135 344666666677688***********9 PP >> tr|F5GX79|F5GX79_HUMAN Elongator complex protein 2 (Fragment) OS=Homo sapiens GN=ELP2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 0.0058 0.47 3 37 .. 2 41 .. 1 41 [. 0.76 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 0.0058 EEEEEE.SS.SSE.EEEEEETTSSE..EEEEETTSEEEEE CS WD40 3 clrtlt.GH.ssv.tslafspdgaw..lasGsdDgtvriW 37 cl+tl G + +l+f p+ + la+G dD+ ++i+ tr|F5GX79|F5GX79_HUMAN 2 CLQTLNfGNgFALaLCLSFLPNTDVpiLACGNDDCRIHIF 41 6666665663334479999999999*8888989****995 PP >> sp|Q6P4I2|WDR73_HUMAN WD repeat-containing protein 73 OS=Homo sapiens GN=WDR73 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 1.4 1.1e+02 14 38 .] 289 304 .. 256 304 .. 0.65 2 ? 7.1 0.1 0.68 55 3 38 .] 323 370 .. 321 370 .. 0.77 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 1.4 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 ++l +sG Dgtv ++d sp|Q6P4I2|WDR73_HUMAN 289 NCL--------AISGF-DGTVQVYD 304 233........55788.******98 PP == domain 2 score: 7.1 bits; conditional E-value: 0.68 EEEEEESS...SS........EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH...ss........vtslafspdgaw.lasGsdDgtvriWd 38 +l t +GH ++ vt ++p + l+s++ D ++++Wd sp|Q6P4I2|WDR73_HUMAN 323 PLFTHRGHiflDGngmdpaplVTTHTWHPCRPRtLLSATNDASLHVWD 370 5667778866522567778888999788888889889999*******9 PP >> tr|D6RE75|D6RE75_HUMAN WD repeat-containing protein 19 (Fragment) OS=Homo sapiens GN=WDR19 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 2.8 2.3e+02 17 38 .] 45 66 .. 31 66 .. 0.87 2 ? 4.1 0.0 5.8 4.7e+02 6 34 .. 75 103 .. 70 105 .. 0.82 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 2.8 EEETTSSEEEEEETTSEEEEEE CS WD40 17 afspdgawlasGsdDgtvriWd 38 +s+ g++la G+ +g++ i++ tr|D6RE75|D6RE75_HUMAN 45 LWSKVGSFLAVGTVKGNLLIYN 66 49999**************997 PP == domain 2 score: 4.1 bits; conditional E-value: 5.8 EEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtv 34 +l H + +t+ +++ ++ + + G++D+ + tr|D6RE75|D6RE75_HUMAN 75 VLGKHtKRITCGCWNAENLLAL-GGEDKMI 103 56679888**999*99999988.9999987 PP >> tr|I3L3A5|I3L3A5_HUMAN WD repeat domain phosphoinositide-interacting protein 3 (Fragment) OS=Homo sapiens GN=WDR45B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.016 1.3 11 37 .. 11 37 .. 1 37 [. 0.81 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.016 SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriW 37 +++++ f++d ++++ +sd gtv+i+ tr|I3L3A5|I3L3A5_HUMAN 11 ANIYCINFNQDASLICVSSDHGTVHIF 37 34*************999999999985 PP >> sp|O75529-2|TAF5L_HUMAN Isoform 2 of TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 0.0086 0.7 18 38 .] 276 296 .. 252 296 .. 0.84 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.0086 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 spd+++la+G d+ +++W+ sp|O75529-2|TAF5L_HUMAN 276 ISPDSKLLAAGFDNSCIKLWS 296 8**********99*******5 PP >> tr|H0YLI3|H0YLI3_HUMAN Transducin-like enhancer protein 3 (Fragment) OS=Homo sapiens GN=TLE3 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 0.01 0.83 6 38 .] 553 584 .. 548 584 .. 0.83 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.01 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriWd 38 tl H+ v+++ s + + +G+ +g v+iWd tr|H0YLI3|H0YLI3_HUMAN 553 TL-SHGEvVCAVTISNPTRHVYTGG-KGCVKIWD 584 55.48555799999999999*****.*******9 PP >> tr|D6RAP6|D6RAP6_HUMAN Anaphase-promoting complex subunit 4 (Fragment) OS=Homo sapiens GN=ANAPC4 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.033 2.6 11 26 .. 66 81 .. 49 91 .. 0.79 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.033 SSEEEEEEETTSSEEE CS WD40 11 ssvtslafspdgawla 26 + vt+la+ pdg++la tr|D6RAP6|D6RAP6_HUMAN 66 KEVTCLAWRPDGKLLA 81 34************96 PP >> tr|G3V2K8|G3V2K8_HUMAN WD repeat-containing protein 25 OS=Homo sapiens GN=WDR25 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 0.012 0.95 2 35 .. 237 274 .] 236 274 .] 0.75 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.012 EEEEEEESS.SSEEEEEEETTSSE.........EEEEETTSEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.........lasGsdDgtvr 35 + l +l+GH ++v+ + +w l+s s+D+t + tr|G3V2K8|G3V2K8_HUMAN 237 KVLFHLRGHrGPVNTI------QWcpvlskshmLLSTSMDKTFK 274 6789*****999****......66666555666666777*9976 PP >> sp|Q9H977|WDR54_HUMAN WD repeat-containing protein 54 OS=Homo sapiens GN=WDR54 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.0 0.35 29 8 38 .] 249 280 .. 242 280 .. 0.67 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.35 ESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +H +++l+ s g++l s+++D v+iW+ sp|Q9H977|WDR54_HUMAN 249 NAHaRAICALDlASEVGKLL-SAGEDTFVHIWK 280 57855599995444445555.6777*******6 PP >> tr|G3V367|G3V367_HUMAN WD repeat-containing protein 25 OS=Homo sapiens GN=WDR25 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.013 1 2 35 .. 237 274 .. 236 274 .. 0.75 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.013 EEEEEEESS.SSEEEEEEETTSSE.........EEEEETTSEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.........lasGsdDgtvr 35 + l +l+GH ++v+ + +w l+s s+D+t + tr|G3V367|G3V367_HUMAN 237 KVLFHLRGHrGPVNTI------QWcpvlskshmLLSTSMDKTFK 274 6789*****999****......66666555666666777*9976 PP >> tr|K7ERR2|K7ERR2_HUMAN Echinoderm microtubule-associated protein-like 2 (Fragment) OS=Homo sapiens GN=EML2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 0.01 0.81 2 21 .. 74 94 .. 73 97 .. 0.88 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.01 EEEEEEESS.SSEEEEEEETT CS WD40 2 qclrtltGH.ssvtslafspd 21 q +r++ GH +++ +la +pd tr|K7ERR2|K7ERR2_HUMAN 74 QRQRHYLGHnDDIKCLAIHPD 94 779******666*******98 PP >> tr|C9J627|C9J627_HUMAN Intraflagellar transport protein 80 homolog (Fragment) OS=Homo sapiens GN=IFT80 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.1 0.094 7.6 10 38 .] 13 41 .. 5 41 .. 0.81 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.094 SSS.EEEEEEETTSSE.....EEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgaw.....lasGsdDgtvriWd 38 H+ v+++ w l s+sdD+ + W+ tr|C9J627|C9J627_HUMAN 13 HQElVSCV------GWttaeeLYSCSDDHQIVKWN 41 6446999*......898888889********9997 PP >> tr|H7C4E4|H7C4E4_HUMAN Transducin-like enhancer protein 4 (Fragment) OS=Homo sapiens GN=TLE4 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 0.014 1.2 9 38 .] 301 330 .. 294 330 .. 0.83 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 H+ v+++ s + + +G+ +g v++Wd tr|H7C4E4|H7C4E4_HUMAN 301 NHGEvVCAVTISNPTRHVYTGG-KGCVKVWD 330 47555799999999999*****.*******9 PP >> tr|B4E2F0|B4E2F0_HUMAN Nucleoporin Nup43 OS=Homo sapiens GN=NUP43 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 9.2 7.5e+02 7 29 .. 71 93 .. 65 157 .. 0.83 2 ? 10.4 0.7 0.058 4.7 12 38 .] 162 194 .. 153 194 .. 0.79 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 9.2 EESSSSEEEEEEETTSSEEEEEE CS WD40 7 ltGHssvtslafspdgawlasGs 29 ++ H++v +l+f + + +a++s tr|B4E2F0|B4E2F0_HUMAN 71 IRHHGDVMDLQFFDQERIVAASS 93 56678899998888888888766 PP == domain 2 score: 10.4 bits; conditional E-value: 0.058 S.....EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 12 s.....vtslafspdgaw.lasGsdDgtvriWd 38 v+ + f+p+++ l+++s+Dg++ Wd tr|B4E2F0|B4E2F0_HUMAN 162 EavrtiVWEVHFHPSNPEhLFTCSEDGSLWHWD 194 345554789999999999456***********8 PP >> tr|C9J0A8|C9J0A8_HUMAN WD repeat domain phosphoinositide-interacting protein 4 (Fragment) OS=Homo sapiens GN=WDR45 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.51 41 12 38 .] 8 33 .. 2 33 .. 0.82 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.51 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +vtsl+f++d++ ++ + + vri++ tr|C9J0A8|C9J0A8_HUMAN 8 GVTSLRFNQDQSCFC-CAMETGVRIYN 33 49***********96.55599999997 PP >> tr|C9JTV2|C9JTV2_HUMAN WD repeat-containing protein mio (Fragment) OS=Homo sapiens GN=MIOS PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.2 0.035 2.9 21 38 .] 125 146 .. 108 146 .. 0.80 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.035 TSSEEEEEET....TSEEEEEE CS WD40 21 dgawlasGsd....DgtvriWd 38 d++wla+G d D +v iWd tr|C9JTV2|C9JTV2_HUMAN 125 DSNWLAAGLDkhraDFSVLIWD 146 89*****9433556*******9 PP >> tr|H0YN92|H0YN92_HUMAN DDB1- and CUL4-associated factor 11 (Fragment) OS=Homo sapiens GN=DCAF11 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.014 1.1 17 38 .] 151 174 .. 126 174 .. 0.86 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.014 E..EETTSSEEEEEETTSEEEEEE CS WD40 17 a..fspdgawlasGsdDgtvriWd 38 + +s+dg+ ++s++ D+t+r++d tr|H0YN92|H0YN92_HUMAN 151 CgiYSKDGQIFMSACQDQTIRLYD 174 25589*****************98 PP >> tr|Q5TA04|Q5TA04_HUMAN WD repeat-containing protein 96 OS=Homo sapiens GN=WDR96 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.2 2.3 1.9e+02 5 34 .. 610 639 .. 606 641 .. 0.82 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 2.3 EEEESSSSEEEEEEETTSSEEE.EEETTSEE CS WD40 5 rtltGHssvtslafspdgawla.sGsdDgtv 34 ++ GH ++ s++ s dg+ ++ G dDgt+ tr|Q5TA04|Q5TA04_HUMAN 610 HSHQGH-GIQSMRISMDGQNILvNGRDDGTL 639 667799.9************7527989**97 PP >> tr|F5GXJ6|F5GXJ6_HUMAN Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sap # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 1.6 1.3e+02 13 36 .. 8 32 .. 4 34 .. 0.73 2 ? 4.5 0.0 4.3 3.5e+02 11 27 .. 65 81 .. 56 90 .. 0.84 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 1.6 EEEEEEETTSSE..EEEEETTSEEEE CS WD40 13 vtslafspdgaw..lasGsdDgtvri 36 +t+ f+p++ + s+s +gt+r+ tr|F5GXJ6|F5GXJ6_HUMAN 8 ITAAEFHPHQCNvfVYSSS-KGTIRL 32 5666777777772246999.*****8 PP == domain 2 score: 4.5 bits; conditional E-value: 4.3 SSEEEEEEETTSSEEEE CS WD40 11 ssvtslafspdgawlas 27 ss+++++fs++g+++++ tr|F5GXJ6|F5GXJ6_HUMAN 65 SSISDVKFSHSGRYMMT 81 46999********9875 PP >> sp|Q9NV06-2|DCA13_HUMAN Isoform 2 of DDB1- and CUL4-associated factor 13 OS=Homo sapiens GN=DCAF13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.016 1.3 4 33 .. 59 90 .. 57 93 .. 0.74 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.016 EEEEESS.SSEEEEEEETTSSE.EEEEETTSE CS WD40 4 lrtltGH.ssvtslafspdgaw.lasGsdDgt 33 l +l+GH ++v++la +p++ ++sG Dg sp|Q9NV06-2|DCA13_HUMAN 59 LASLDGHrDGVNCLAKHPEKLAtVLSGACDGE 90 6789***999****966665445678855876 PP >> sp|Q8WUA4-2|TF3C2_HUMAN Isoform 2 of General transcription factor 3C polypeptide 2 OS=Homo sapiens GN=GTF3C2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.03 2.4 12 37 .. 468 511 .. 451 512 .. 0.83 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.03 S.EEEEEEETTSSE...................EEEEETTSEEEEE CS WD40 12 s.vtslafspdgaw...................lasGsdDgtvriW 37 + +++l+f+p+gaw l ++s Dg+v ++ sp|Q8WUA4-2|TF3C2_HUMAN 468 GcIWDLKFCPSGAWelpgtprkapllprlgllaL-ACS-DGKVLLF 511 2499999***********************8533.79*.***9886 PP >> sp|Q9BSC4-2|NOL10_HUMAN Isoform 2 of Nucleolar protein 10 OS=Homo sapiens GN=NOL10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 0.0 0.47 38 13 38 .] 54 81 .. 47 81 .. 0.85 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.47 E.EEEEEETTSSEE.EEEETTSEEEEEE CS WD40 13 v.tslafspdgawl.asGsdDgtvriWd 38 v t +++s+dg+++ a+G++++ vr +d sp|Q9BSC4-2|NOL10_HUMAN 54 VcTTIKVSKDGQYIlATGTYKPRVRCYD 81 558899*******6369999*****998 PP >> tr|H0YL77|H0YL77_HUMAN Uncharacterized protein (Fragment) OS=Homo sapiens PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.1 1.4 1.1e+02 4 38 .] 18 59 .. 16 59 .. 0.69 2 ? 8.7 0.1 0.2 16 3 29 .. 65 92 .. 63 102 .. 0.86 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 1.4 EEEEESSSSE.EEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHssv.tsla.......fspdgawlasGsdDgtvriWd 38 l t++GH +v + l s ++++ sG+ g+v ++d tr|H0YL77|H0YL77_HUMAN 18 LMTYRGH-GVlHTLIrcrfspiHSTGQQFIYSGCSTGKVVVYD 59 789****.75444445555576666667788997699998887 PP == domain 2 score: 8.7 bits; conditional E-value: 0.2 EEEEEESS.SSEEEEEEETTSSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGs 29 +++lt H +v++++++p ++s+s tr|H0YL77|H0YL77_HUMAN 65 IVKKLTNHkACVRDVSWHPFEEKIVSSS 92 578899**666*********99999987 PP >> tr|M0R0E3|M0R0E3_HUMAN SH3KBP1-binding protein 1 (Fragment) OS=Homo sapiens GN=SHKBP1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.18 15 2 37 .. 69 104 .. 68 105 .. 0.80 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.18 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 q+ +t+t H s+vt + +++++++ + d+++vr W tr|M0R0E3|M0R0E3_HUMAN 69 QLFQTFTVHrSPVTKI-MLSEKHLISVCADNNHVRTW 104 67899****999**99.5555555666889*****99 PP >> tr|K7ERN7|K7ERN7_HUMAN Notchless protein homolog 1 OS=Homo sapiens GN=NLE1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.027 2.2 2 22 .. 105 126 .. 104 127 .] 0.84 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.027 EEEEEEESS.SSEEEEEEETTS CS WD40 2 qclrtltGH.ssvtslafspdg 22 +c+ +l+GH v s+afsp g tr|K7ERN7|K7ERN7_HUMAN 105 RCTSSLEGHsEAVISVAFSPTG 126 6999*****54488******98 PP >> tr|M0QYB1|M0QYB1_HUMAN SH3KBP1-binding protein 1 (Fragment) OS=Homo sapiens GN=SHKBP1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.0 0.17 14 2 37 .. 56 91 .. 55 92 .. 0.80 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.17 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 q+ +t+t H s+vt + +++++++ + d+++vr W tr|M0QYB1|M0QYB1_HUMAN 56 QLFQTFTVHrSPVTKI-MLSEKHLISVCADNNHVRTW 91 67899****999**99.5555555666889*****99 PP >> sp|Q5MNZ6|WIPI3_HUMAN WD repeat domain phosphoinositide-interacting protein 3 OS=Homo sapiens GN=WDR45B PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 9.5 7.7e+02 8 34 .. 182 209 .. 175 214 .. 0.81 2 ? 10.7 0.3 0.048 3.9 9 37 .. 227 257 .. 210 257 .. 0.77 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 9.5 ESSSSE.EEEEEETTSSEEEEEETTSEE CS WD40 8 tGHssv.tslafspdgawlasGsdDgtv 34 +H +v +++a + g+ +a++s++gt+ sp|Q5MNZ6|WIPI3_HUMAN 182 PAHEGVlSCIALNLQGTRIATASEKGTL 209 57977779**99999999****987775 PP == domain 2 score: 10.7 bits; conditional E-value: 0.048 SSSS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss...vtslafspdgawlasGsdDgtvriW 37 G ++++ f++d ++++ +sd gtv+i+ sp|Q5MNZ6|WIPI3_HUMAN 227 GS-QaanIYCINFNQDASLICVSSDHGTVHIF 257 44.0345*************999999999985 PP >> tr|H0Y4P4|H0Y4P4_HUMAN EF-hand calcium-binding domain-containing protein 8 (Fragment) OS=Homo sapiens GN=EFCAB8 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.5 0.18 14 22 38 .] 287 304 .. 274 304 .. 0.84 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.18 SSEE.EEEETTSEEEEEE CS WD40 22 gawl.asGsdDgtvriWd 38 ++w+ ++G+ +g ++iWd tr|H0Y4P4|H0Y4P4_HUMAN 287 NDWIlITGDCKGYIKIWD 304 6896269977*******9 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (38 nodes) Target sequences: 88473 (35070517 residues searched) Passed MSV filter: 3287 (0.0371526); expected 1769.5 (0.02) Passed bias filter: 2894 (0.0327105); expected 1769.5 (0.02) Passed Vit filter: 1262 (0.0142642); expected 88.5 (0.001) Passed Fwd filter: 1095 (0.0123767); expected 0.9 (1e-05) Initial search space (Z): 88473 [actual number of targets] Domain search space (domZ): 1092 [number of targets reported over threshold] # CPU time: 1.05u 0.05s 00:00:01.10 Elapsed: 00:00:00.39 # Mc/sec: 3417.13 // [ok]