# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/WD40.hmm.txt # target sequence database: proteomes/Saccharomyces_cerevisiae.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: WD40 [M=38] Accession: PF00400.32 Description: WD domain, G-beta repeat Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-63 207.1 36.9 7.6e-13 47.2 0.3 9.1 9 sp|P25382|NLE1_YEAST Ribosome assembly protein 4 OS=Sacchar 4.1e-51 168.3 12.1 3.4e-09 35.7 0.0 7.4 7 sp|P16649|TUP1_YEAST General transcriptional corepressor TU 4.4e-51 168.2 21.5 3.9e-10 38.7 0.3 6.7 6 sp|P38129|TAF5_YEAST Transcription initiation factor TFIID 2.3e-48 159.6 34.4 8.4e-07 28.1 0.2 10.8 10 sp|Q12220|UTP12_YEAST U3 small nucleolar RNA-associated prot 2e-47 156.7 11.7 5e-09 35.2 0.1 12.6 11 sp|P25635|PWP2_YEAST Periodic tryptophan protein 2 OS=Sacch 5.8e-46 152.0 16.5 9e-07 28.0 0.0 10.5 10 sp|Q05946|UTP13_YEAST U3 small nucleolar RNA-associated prot 1.7e-44 147.4 11.0 1.1e-07 30.9 0.3 7.2 7 sp|P38011|GBLP_YEAST Guanine nucleotide-binding protein sub 8.8e-43 142.0 17.8 4.4e-11 41.7 0.1 8.0 8 sp|P41318|LST8_YEAST Target of rapamycin complex subunit LS 3.2e-40 133.9 17.7 1.2e-08 33.9 0.1 7.0 6 sp|P53622|COPA_YEAST Coatomer subunit alpha OS=Saccharomyce 3.5e-40 133.8 13.3 4.5e-09 35.3 0.0 10.2 8 sp|P42935|ELP2_YEAST Elongator complex protein 2 OS=Sacchar 2.6e-36 121.5 19.6 2.5e-06 26.6 0.3 7.7 6 sp|P07834|CDC4_YEAST Cell division control protein 4 OS=Sac 1.2e-35 119.4 5.1 3.2e-07 29.4 0.0 8.5 7 sp|P41811|COPB2_YEAST Coatomer subunit beta' OS=Saccharomyce 3e-35 118.1 25.6 6e-07 28.6 0.7 8.2 7 sp|P39014|MET30_YEAST F-box protein MET30 OS=Saccharomyces c 6.2e-35 117.1 21.0 8.1e-08 31.3 0.0 7.2 7 sp|Q05583|CIAO1_YEAST Cytosolic iron-sulfur protein assembly 2.9e-34 115.0 5.4 1.7e-08 33.5 0.2 6.1 5 sp|P47025|MDV1_YEAST Mitochondrial division protein 1 OS=Sa 1.2e-32 109.9 19.4 4.5e-08 32.1 0.1 7.1 7 sp|P20053|PRP4_YEAST U4/U6 small nuclear ribonucleoprotein 3.2e-32 108.5 21.2 3.4e-09 35.7 0.0 7.9 7 sp|P36037|DOA1_YEAST Protein DOA1 OS=Saccharomyces cerevisi 8.5e-31 104.0 15.6 8.1e-06 25.0 0.1 7.3 7 sp|Q12417|PRP46_YEAST Pre-mRNA-splicing factor PRP46 OS=Sacc 1.4e-30 103.4 11.7 1e-06 27.8 0.1 6.9 6 sp|P42841|PFS2_YEAST Polyadenylation factor subunit 2 OS=Sa 3.3e-30 102.2 7.1 5.1e-07 28.8 0.0 6.2 5 sp|P40968|PRP17_YEAST Pre-mRNA-processing factor 17 OS=Sacch 4e-30 101.9 18.6 5.6e-09 35.0 0.1 7.8 7 sp|P32479|HIR1_YEAST Protein HIR1 OS=Saccharomyces cerevisi 8.4e-30 100.9 17.1 6.7e-07 28.4 0.3 7.3 7 sp|P18851|GBB_YEAST Guanine nucleotide-binding protein sub 2.9e-28 96.0 9.4 3e-07 29.5 0.0 6.8 6 sp|P36130|CAF4_YEAST CCR4-associated factor 4 OS=Saccharomy 5.6e-27 92.0 8.6 3.2e-06 26.3 0.0 6.7 6 sp|P33750|DCA13_YEAST Protein SOF1 OS=Saccharomyces cerevisi 2.7e-26 89.8 17.7 5.6e-08 31.8 0.1 6.6 5 sp|Q12024|YTM1_YEAST Ribosome biogenesis protein YTM1 OS=Sa 8.5e-25 85.1 6.1 9.3e-10 37.5 0.2 6.7 6 sp|Q04660|ERB1_YEAST Ribosome biogenesis protein ERB1 OS=Sa 1.4e-24 84.4 10.9 4.5e-07 29.0 0.0 7.2 7 sp|P38123|SWD3_YEAST COMPASS component SWD3 OS=Saccharomyce 2e-24 83.9 6.2 9.5e-06 24.8 1.0 6.2 6 sp|P40217|EIF3I_YEAST Eukaryotic translation initiation fact 2e-24 83.9 22.1 4.3e-06 25.9 0.4 7.4 7 sp|P39946|LIS1_YEAST Nuclear distribution protein PAC1 OS=S 3.4e-23 80.0 12.3 4e-07 29.1 0.6 6.1 5 sp|P20484|MAK11_YEAST Protein MAK11 OS=Saccharomyces cerevis 2.1e-21 74.3 16.8 1.2e-05 24.5 0.6 6.4 6 sp|Q04491|SEC13_YEAST Protein transport protein SEC13 OS=Sac 2.7e-21 74.0 11.9 0.00031 20.0 0.0 5.6 5 sp|Q04199|CAC2_YEAST Chromatin assembly factor 1 subunit p6 5.8e-21 72.9 15.4 2.4e-05 23.5 0.4 5.6 5 sp|P53011|SEH1_YEAST Nucleoporin SEH1 OS=Saccharomyces cere 9.2e-21 72.3 12.2 7.2e-06 25.2 0.1 5.5 4 sp|P38262|SIF2_YEAST SIR4-interacting protein SIF2 OS=Sacch 7e-20 69.5 5.6 6.1e-06 25.4 0.3 4.7 4 sp|P40066|GLE2_YEAST Nucleoporin GLE2 OS=Saccharomyces cere 3.2e-19 67.4 16.2 0.025 14.0 0.0 10.6 8 sp|P46680|AIP1_YEAST Actin-interacting protein 1 OS=Sacchar 6.7e-19 66.4 11.9 0.0005 19.3 0.0 6.1 5 sp|P53197|CDH1_YEAST APC/C activator protein CDH1 OS=Saccha 1e-18 65.8 15.1 6.6e-06 25.3 0.1 6.1 5 sp|Q03177|YMZ2_YEAST WD repeat-containing protein YMR102C O 1.9e-17 61.8 9.2 0.0002 20.6 1.3 6.6 6 sp|P13712|MSI1_YEAST Chromatin assembly factor 1 subunit p5 5.4e-17 60.4 11.7 0.0014 17.9 0.0 6.3 6 sp|P39108|PEX7_YEAST Peroxisomal targeting signal 2 recepto 6e-17 60.2 5.4 5.8e-05 22.3 0.0 4.8 4 sp|Q06440|CORO_YEAST Coronin-like protein OS=Saccharomyces 6.3e-17 60.1 1.3 3.4e-08 32.5 0.2 5.2 4 sp|P39706|SWD1_YEAST COMPASS component SWD1 OS=Saccharomyce 1e-16 59.5 0.5 5.7e-05 22.3 0.0 5.9 5 sp|P36104|SWD2_YEAST COMPASS component SWD2 OS=Saccharomyce 2.3e-16 58.4 5.6 0.011 15.0 0.0 6.9 6 sp|Q04305|UTP15_YEAST U3 small nucleolar RNA-associated prot 3.1e-16 58.0 1.8 2.2e-05 23.6 0.0 5.8 5 sp|Q06506|RRP9_YEAST Ribosomal RNA-processing protein 9 OS= 1e-15 56.3 0.1 5.3e-05 22.4 0.0 5.6 4 sp|P53196|RPN14_YEAST 26S proteasome regulatory subunit RPN1 1.2e-15 56.1 20.1 7.6e-07 28.2 0.1 9.1 6 sp|Q08924|WDR6_YEAST Regulator of Ty1 transposition protein 1.6e-15 55.7 0.2 0.0014 17.9 0.0 7.0 6 sp|Q00362|2ABA_YEAST Protein phosphatase PP2A regulatory su 2.5e-15 55.1 0.6 8.6e-05 21.7 0.1 4.8 4 sp|P39984|HAT2_YEAST Histone acetyltransferase type B subun 2.9e-15 54.9 0.6 0.00075 18.8 0.0 6.2 4 sp|P25569|GID7_YEAST Glucose-induced degradation protein 7 4.5e-15 54.3 1.5 1.8e-05 23.9 0.0 5.2 4 sp|P40362|UTP18_YEAST U3 small nucleolar RNA-associated prot 3.9e-14 51.3 2.9 6.9e-06 25.2 0.1 3.9 3 sp|P40042|RRT13_YEAST Regulator of rDNA transcription protei 7.1e-14 50.5 7.4 0.0012 18.1 0.3 4.9 4 sp|Q12021|RAD28_YEAST Radiation-sensitive protein 28 OS=Sacc 1.7e-13 49.3 16.4 7.7e-05 21.9 0.2 5.6 4 sp|P26309|CDC20_YEAST APC/C activator protein CDC20 OS=Sacch 2.2e-13 48.9 19.3 0.01 15.2 0.0 8.7 7 sp|Q06679|UTP4_YEAST U3 small nucleolar RNA-associated prot 3.9e-13 48.2 3.7 0.00039 19.7 0.0 6.0 5 sp|P38149|DUG2_YEAST Probable di- and tripeptidase DUG2 OS= 1.1e-12 46.7 15.3 2.5e-07 29.8 0.3 8.1 7 sp|Q06078|UTP21_YEAST U3 small nucleolar RNA-associated prot 4.4e-12 44.8 17.1 8.5e-05 21.8 0.2 6.7 5 sp|P32330|DGR2_YEAST 2-deoxy-glucose resistant protein 2 OS 3.2e-11 42.1 16.7 1.2e-05 24.5 0.6 5.4 4 sp|Q02793|SKI8_YEAST Antiviral protein SKI8 OS=Saccharomyce 3.6e-11 41.9 8.0 0.0005 19.3 0.0 5.3 4 sp|Q04225|RRB1_YEAST Ribosome assembly protein RRB1 OS=Sacc 4.8e-11 41.5 6.4 0.0018 17.5 0.2 6.0 5 sp|P38328|ARPC1_YEAST Actin-related protein 2/3 complex subu 5.9e-11 41.3 14.5 2.1e-05 23.7 0.3 4.9 3 sp|Q12523|YP247_YEAST WD repeat-containing protein YPL247C O 9.8e-11 40.6 14.7 0.00039 19.7 0.1 7.1 5 sp|P38968|SEC31_YEAST Protein transport protein SEC31 OS=Sac 4.7e-10 38.4 1.0 0.00021 20.5 0.0 3.8 2 sp|Q08281|RTC1_YEAST Restriction of telomere capping protei 3e-09 35.9 5.3 0.044 13.2 0.0 5.8 3 sp|P50082|AMA1_YEAST Meiosis-specific APC/C activator prote 2.6e-08 32.9 5.3 0.0013 18.0 0.5 4.1 3 sp|P53962|YND5_YEAST Uncharacterized WD repeat-containing p 4.7e-08 32.1 2.2 0.049 13.0 0.0 5.4 4 sp|Q12510|CMR1_YEAST DNA damage-binding protein CMR1 OS=Sac 5.6e-08 31.8 6.8 0.0043 16.4 0.6 5.7 4 sp|P21304|PWP1_YEAST Periodic tryptophan protein 1 OS=Sacch 7.9e-08 31.4 3.3 0.0022 17.3 0.3 5.0 3 sp|Q02931|UTP17_YEAST NET1-associated nuclear protein 1 OS=S 8.5e-08 31.3 9.0 0.0029 16.9 0.1 5.9 4 sp|P53851|TEX1_YEAST Protein TEX1 OS=Saccharomyces cerevisi 9.2e-08 31.1 0.0 0.036 13.5 0.0 3.5 2 sp|P43601|ATG18_YEAST Autophagy-related protein 18 OS=Saccha 1.2e-07 30.8 4.3 7.1 6.2 0.0 6.1 5 sp|P38915|SPT8_YEAST Transcription factor SPT8 OS=Saccharom 3.6e-07 29.3 0.7 0.004 16.5 0.0 4.3 3 sp|P26449|BUB3_YEAST Cell cycle arrest protein BUB3 OS=Sacc 6.8e-07 28.4 0.6 0.51 9.8 0.1 4.0 3 sp|P38163|SRO77_YEAST Lethal(2) giant larvae protein homolog 1.7e-06 27.1 0.1 0.03 13.7 0.0 4.9 3 sp|P25365|SED4_YEAST Putative guanine nucleotide-exchange f 2.5e-06 26.6 0.2 0.0042 16.4 0.0 4.4 2 sp|P40055|UTP7_YEAST U3 small nucleolar RNA-associated prot 3.3e-06 26.2 3.7 0.089 12.2 0.0 6.0 5 sp|P38873|KOG1_YEAST Target of rapamycin complex 1 subunit 3.6e-06 26.1 22.6 2.5e-05 23.4 0.2 5.6 5 sp|Q03897|WDR59_YEAST Maintenance of telomere capping protei 7.6e-06 25.1 1.7 0.42 10.1 0.1 4.6 3 sp|Q99247|YO087_YEAST Uncharacterized WD repeat-containing p 1e-05 24.7 0.4 0.68 9.4 0.0 4.4 3 sp|P53877|IPI3_YEAST Pre-rRNA-processing protein IPI3 OS=Sa 2.8e-05 23.3 7.4 2.8 7.5 0.1 6.8 4 sp|P47104|RAV1_YEAST Regulator of V-ATPase in vacuolar memb 3.7e-05 22.9 0.4 0.0036 16.6 0.1 3.7 2 sp|Q02887|ATG21_YEAST Autophagy-related protein 21 OS=Saccha 9.4e-05 21.6 5.1 0.0058 16.0 0.2 3.6 2 sp|Q12363|WTM1_YEAST Transcriptional modulator WTM1 OS=Sacc 9.9e-05 21.5 0.1 0.0014 17.9 0.1 3.0 1 sp|P38959|VPS41_YEAST Vacuolar protein sorting-associated pr 0.00035 19.8 7.3 0.0046 16.3 0.3 4.0 3 sp|Q12206|WTM2_YEAST Transcriptional modulator WTM2 OS=Sacc 0.00058 19.1 1.1 0.0044 16.3 0.1 2.8 1 sp|P40960|PAC11_YEAST WD repeat-containing protein PAC11 OS= 0.00064 19.0 3.2 0.92 9.0 0.1 4.7 3 sp|P53235|EIF2A_YEAST Eukaryotic translation initiation fact 0.00082 18.7 1.4 0.61 9.6 0.0 4.9 3 sp|P32480|HIR2_YEAST Protein HIR2 OS=Saccharomyces cerevisi 0.001 18.3 5.6 0.55 9.7 1.0 4.2 3 sp|Q03774|TRM82_YEAST tRNA (guanine-N(7)-)-methyltransferase 0.0018 17.6 3.9 0.06 12.8 0.0 3.9 2 sp|Q03010|UME1_YEAST Transcriptional regulatory protein UME 0.0055 16.0 1.4 0.3 10.5 0.0 3.9 2 sp|P11655|SEC12_YEAST Guanine nucleotide-exchange factor SEC 0.0074 15.6 0.9 1.5 8.3 0.0 4.1 2 sp|P38164|SEA4_YEAST SEH-associated protein 4 OS=Saccharomy 0.0098 15.2 1.4 0.24 10.8 0.0 3.5 2 sp|P22219|VPS15_YEAST Serine/threonine-protein kinase VPS15 ------ inclusion threshold ------ 0.017 14.5 0.4 31 4.2 0.0 4.0 3 sp|P48234|NOL10_YEAST Ribosome biogenesis protein ENP2 OS=Sa 0.018 14.4 0.0 33 4.1 0.0 4.5 4 sp|Q12038|SRO7_YEAST Lethal(2) giant larvae protein homolog 0.019 14.3 0.0 0.11 11.9 0.0 2.3 1 sp|Q00772|SLT2_YEAST Mitogen-activated protein kinase SLT2/ 0.04 13.3 0.0 5.7 6.5 0.0 3.4 2 sp|P50079|HSV2_YEAST SVP1-like protein 2 OS=Saccharomyces c 0.075 12.4 5.5 27 4.4 0.0 5.0 4 sp|P38332|DPH7_YEAST Diphthine methyltransferase OS=Sacchar 0.16 11.4 8.5 1.2 8.6 0.0 4.9 3 sp|P40077|DSE1_YEAST Protein DSE1 OS=Saccharomyces cerevisi 0.29 10.6 11.4 1.2 8.6 0.3 4.9 3 sp|P35184|SQT1_YEAST Ribosome assembly protein SQT1 OS=Sacc 1.5 8.4 5.5 2.1 7.9 0.1 4.0 1 sp|Q06214|JIP5_YEAST WD repeat-containing protein JIP5 OS=S Domain annotation for each sequence (and alignments): >> sp|P25382|NLE1_YEAST Ribosome assembly protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.2 0.00029 0.017 8 38 .] 140 172 .. 133 172 .. 0.68 2 ! 47.2 0.3 1.3e-14 7.6e-13 2 38 .] 177 214 .. 176 214 .. 0.97 3 ! 28.8 0.3 8.6e-09 5.1e-07 1 38 [] 218 264 .. 218 264 .. 0.85 4 ! 31.5 1.2 1.2e-09 6.9e-08 2 38 .] 269 305 .. 268 305 .. 0.87 5 ? 6.7 0.2 0.083 5 1 33 [. 310 342 .. 310 345 .. 0.82 6 ? 3.4 0.0 0.91 55 24 38 .] 373 387 .. 355 387 .. 0.86 7 ! 35.1 0.0 8.7e-11 5.2e-09 3 38 .] 394 430 .. 392 430 .. 0.90 8 ! 34.2 0.9 1.6e-10 9.7e-09 2 38 .] 435 472 .. 434 472 .. 0.95 9 ! 26.7 0.2 3.9e-08 2.3e-06 7 37 .. 482 513 .. 476 514 .. 0.88 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 0.00029 ESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 GH s + + a + ++++ ++G D+t riWd sp|P25382|NLE1_YEAST 140 AGHgSTILCSAfaPHTSSRM-VTGAGDNTARIWD 172 59*76785555115555555.57855*******9 PP == domain 2 score: 47.2 bits; conditional E-value: 1.3e-14 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++tl+GH ++v ++++spdg +a+Gs+D+t+r+Wd sp|P25382|NLE1_YEAST 177 TPMHTLKGHyNWVLCVSWSPDGEVIATGSMDNTIRLWD 214 689**********************************9 PP == domain 3 score: 28.8 bits; conditional E-value: 8.6e-09 TEEEEE.EESS.SSEEEEEEETTSSE.............EEEEETTSEEEEEE CS WD40 1 gqclrt.ltGH.ssvtslafspdgaw.............lasGsdDgtvriWd 38 gqcl+ l+GH +++tsl +w las+s+Dgt++iWd sp|P25382|NLE1_YEAST 218 GQCLGDaLRGHsKWITSL------SWepihlvkpgskprLASSSKDGTIKIWD 264 57788879***999****......666666669999999*************9 PP == domain 4 score: 31.5 bits; conditional E-value: 1.2e-09 EEEEEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw.....lasGsdDgtvriWd 38 c++t +GH +sv+++ +w l sGs D+tvr+Wd sp|P25382|NLE1_YEAST 269 VCQYTMSGHtNSVSCV------KWggqglLYSGSHDRTVRVWD 305 69*******999****......666666558**99*******9 PP == domain 5 score: 6.7 bits; conditional E-value: 0.083 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgt 33 g+c+ +l+ H +v++l+ s d a+ + G D+t sp|P25382|NLE1_YEAST 310 GRCINILKSHaHWVNHLSLSTDYALRI-GAFDHT 342 6899****99556****9999999865.655776 PP == domain 6 score: 3.4 bits; conditional E-value: 0.91 EEEEEETTSEEEEEE CS WD40 24 wlasGsdDgtvriWd 38 +++++sdD t +W+ sp|P25382|NLE1_YEAST 373 MMVTASDDYTMFLWN 387 468999********8 PP == domain 7 score: 35.1 bits; conditional E-value: 8.7e-11 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ tGH + v+++afspdg++++s+s D+++++Wd sp|P25382|NLE1_YEAST 394 PIARMTGHqKLVNHVAFSPDGRYIVSASFDNSIKLWD 430 666789**666****************99*******9 PP == domain 8 score: 34.2 bits; conditional E-value: 1.6e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + t++GH sv+ +a+s+d ++l+s+s+D t+++Wd sp|P25382|NLE1_YEAST 435 KFISTFRGHvASVYQVAWSSDCRLLVSCSKDTTLKVWD 472 6789*****999*************************9 PP == domain 9 score: 26.7 bits; conditional E-value: 3.9e-08 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 l GH++ v+ +++s dg+ ++sG++D+ vr+W sp|P25382|NLE1_YEAST 482 LPGHKDeVYTVDWSVDGKRVCSGGKDKMVRLW 513 78**556************************* PP >> sp|P16649|TUP1_YEAST General transcriptional corepressor TUP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 3.9e-05 0.0023 9 34 .. 342 367 .. 336 371 .. 0.79 2 ! 31.0 0.0 1.7e-09 9.9e-08 12 38 .] 442 471 .. 432 471 .. 0.86 3 ! 35.7 0.0 5.8e-11 3.4e-09 2 38 .] 476 513 .. 475 513 .. 0.94 4 ! 19.0 0.0 1.1e-05 0.00065 2 38 .] 518 555 .. 517 555 .. 0.87 5 ! 27.3 0.2 2.6e-08 1.5e-06 7 38 .] 572 604 .. 568 604 .. 0.92 6 ! 22.6 0.1 7.9e-07 4.7e-05 2 38 .] 621 658 .. 620 658 .. 0.92 7 ! 17.3 0.0 3.7e-05 0.0022 1 38 [] 662 706 .. 662 706 .. 0.82 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 3.9e-05 SSSS.EEEEEEETTSSEEEEEETTSEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtv 34 H+s v++++fs dg +la+G+ ++t sp|P16649|TUP1_YEAST 342 DHTSvVCCVKFSNDGEYLATGC-NKTT 367 486657***************9.8875 PP == domain 2 score: 31.0 bits; conditional E-value: 1.7e-09 S...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvriWd 38 s ++s++fspdg++la+G +D+ +riWd sp|P16649|TUP1_YEAST 442 SdlyIRSVCFSPDGKFLATGAEDRLIRIWD 471 24779************************9 PP == domain 3 score: 35.7 bits; conditional E-value: 5.8e-11 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + +l GH ++++sl++ p+g+ l+sGs D+tvriWd sp|P16649|TUP1_YEAST 476 KIVMILQGHeQDIYSLDYFPSGDKLVSGSGDRTVRIWD 513 567899***999****************99*******9 PP == domain 4 score: 19.0 bits; conditional E-value: 1.1e-05 EEEEEEESSSSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHssvtsla.fspdgawlasGsdDgtvriWd 38 qc tl+ ++vt +a + dg+++a+Gs D+ vr+Wd sp|P16649|TUP1_YEAST 518 QCSLTLSIEDGVTTVAvSPGDGKYIAAGSLDRAVRVWD 555 6777777666799999999******************9 PP == domain 5 score: 27.3 bits; conditional E-value: 2.6e-08 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tGH +sv+s+ f +dg+ ++sGs D++v++W+ sp|P16649|TUP1_YEAST 572 GTGHkDSVYSVVFTRDGQSVVSGSLDRSVKLWN 604 47**777*************************8 PP == domain 6 score: 22.6 bits; conditional E-value: 7.9e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c t+ GH ++v s+a+ ++ +++sGs+D+ v +Wd sp|P16649|TUP1_YEAST 621 TCEVTYIGHkDFVLSVATTQNDEYILSGSKDRGVLFWD 658 68889****666*************************9 PP == domain 7 score: 17.3 bits; conditional E-value: 3.7e-05 TEEEEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla......fspdgawlasGsdDgtvriWd 38 g++l l GH +sv s+a p+ + +a+Gs D++ riW+ sp|P16649|TUP1_YEAST 662 GNPLLMLQGHrNSVISVAvangspLGPEYNVFATGSGDCKARIWK 706 678999*******8788866777766666669***99*******6 PP >> sp|P38129|TAF5_YEAST Transcription initiation factor TFIID subunit 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.1 0.00013 0.0081 3 38 .] 458 494 .. 456 494 .. 0.88 2 ! 34.0 0.1 2e-10 1.2e-08 5 38 .] 519 553 .. 516 553 .. 0.91 3 ! 28.2 0.5 1.4e-08 8.1e-07 5 38 .] 561 595 .. 558 595 .. 0.91 4 ! 38.7 0.3 6.5e-12 3.9e-10 3 38 .] 601 637 .. 599 637 .. 0.96 5 ! 30.5 0.4 2.4e-09 1.4e-07 3 38 .] 643 679 .. 641 679 .. 0.90 6 ! 32.8 0.0 4.6e-10 2.7e-08 2 38 .] 684 722 .. 683 722 .. 0.90 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 0.00013 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c++t+ ++ ++l+fs+d + a+G D ++iW+ sp|P38129|TAF5_YEAST 458 CMYTFQNTnKDMSCLDFSDDCRIAAAGFQDSYIKIWS 494 7888876668899***********************5 PP == domain 2 score: 34.0 bits; conditional E-value: 2e-10 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tl GH + v+s +fspd+++l+sGs+D+tvr+W+ sp|P38129|TAF5_YEAST 519 KTLVGHsGTVYSTSFSPDNKYLLSGSEDKTVRLWS 553 6899**555*************************5 PP == domain 3 score: 28.2 bits; conditional E-value: 1.4e-08 EEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++GH++ v++++fsp g+++a++s D+t r+W+ sp|P38129|TAF5_YEAST 561 VSYKGHNHpVWDVSFSPLGHYFATASHDQTARLWS 595 589***666***************999*******5 PP == domain 4 score: 38.7 bits; conditional E-value: 6.5e-12 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +lr++ GH ++v +++f+p+g ++++Gs D+t+r+Wd sp|P38129|TAF5_YEAST 601 PLRIFAGHlNDVDCVSFHPNGCYVFTGSSDKTCRMWD 637 799************************99*******9 PP == domain 5 score: 30.5 bits; conditional E-value: 2.4e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r + GH +v s+a++pdg+wl++Gs+Dg + +Wd sp|P38129|TAF5_YEAST 643 SVRLFLGHtAPVISIAVCPDGRWLSTGSEDGIINVWD 679 567788**88888***********************9 PP == domain 6 score: 32.8 bits; conditional E-value: 4.6e-10 EEEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH..ssvtslafspdgawlasGsdDgtvriWd 38 + l+ +GH + ++sl++s++g+ l+sG+ D+tvr+Wd sp|P38129|TAF5_YEAST 684 KRLKQMRGHgkNAIYSLSYSKEGNVLISGGADHTVRVWD 722 5678899**9555*************************9 PP >> sp|Q12220|UTP12_YEAST U3 small nucleolar RNA-associated protein 12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 0.0 0.0025 0.15 19 38 .] 88 107 .. 77 107 .. 0.85 2 ! 17.9 0.1 2.4e-05 0.0014 5 38 .] 115 149 .. 111 149 .. 0.90 3 ! 21.7 0.4 1.5e-06 9.2e-05 4 38 .] 156 190 .. 153 190 .. 0.91 4 ? 8.4 0.5 0.024 1.4 2 38 .] 195 230 .. 192 230 .. 0.64 5 ! 22.1 0.0 1.1e-06 6.8e-05 5 38 .] 385 418 .. 380 418 .. 0.90 6 ! 23.4 0.4 4.4e-07 2.6e-05 9 38 .] 471 501 .. 463 501 .. 0.89 7 ! 10.5 0.0 0.0052 0.31 12 37 .. 533 558 .. 517 558 .. 0.81 8 ! 20.2 0.0 4.4e-06 0.00026 6 37 .. 568 600 .. 564 600 .. 0.92 9 ! 13.0 0.3 0.00084 0.051 2 38 .] 606 643 .. 605 643 .. 0.92 10 ! 28.1 0.2 1.4e-08 8.4e-07 2 37 .. 648 684 .. 647 685 .. 0.93 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.0025 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 ++d ++la G Dg +++Wd sp|Q12220|UTP12_YEAST 88 HKDTDLLAVGYADGVIKVWD 107 566777****99*******9 PP == domain 2 score: 17.9 bits; conditional E-value: 2.4e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH +t l+f+ g+ l+sGs+D ++ +Wd sp|Q12220|UTP12_YEAST 115 LNFNGHkAAITLLQFDGTGTRLISGSKDSNIIVWD 149 5789**666*************************9 PP == domain 3 score: 21.7 bits; conditional E-value: 1.5e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++l+ H +s+t++ +++ +wl+s s+Dg +++Wd sp|Q12220|UTP12_YEAST 156 LYKLRSHkDSITGF-WCQGEDWLISTSKDGMIKLWD 190 67899**777****.********************9 PP == domain 4 score: 8.4 bits; conditional E-value: 0.024 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 qc+ t +H + ++la+ ++l+ +G+ D v+iW+ sp|Q12220|UTP12_YEAST 195 QCIETHIAHtGECWGLAV--KDDLLItTGT-DSQVKIWK 230 566666677544666633..3344542777.*******6 PP == domain 5 score: 22.1 bits; conditional E-value: 1.1e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l G+ ++v+s++ s+d+++la++s +g+++iW+ sp|Q12220|UTP12_YEAST 385 IELQGQrTDVRSIDISDDNKLLATAS-NGSLKIWN 418 457899999*****************.*******8 PP == domain 6 score: 23.4 bits; conditional E-value: 4.4e-07 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H ++sl+ +dg+ l++Gs D+tv++Wd sp|Q12220|UTP12_YEAST 471 AHdAAIWSLDLTSDGKRLVTGSADKTVKFWD 501 89666*************************9 PP == domain 7 score: 10.5 bits; conditional E-value: 0.0052 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 ++ ++++spd ++la + D+tv+++ sp|Q12220|UTP12_YEAST 533 DILCVRVSPDDRYLAISLLDNTVKVF 558 499************9978*****95 PP == domain 8 score: 20.2 bits; conditional E-value: 4.4e-06 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l GH +v s++ s d+++++++s D++++iW sp|Q12220|UTP12_YEAST 568 SLYGHkLPVLSIDISFDSKMIITSSADKNIKIW 600 577**777****************99******* PP == domain 9 score: 13.0 bits; conditional E-value: 0.00084 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c ++l +H +s+ ++f p ++ ++s+s+D v+ Wd sp|Q12220|UTP12_YEAST 606 DCHKSLFAHqDSIMNVKFLPQSHNFFSCSKDAVVKYWD 643 67888889*888*************************9 PP == domain 10 score: 28.1 bits; conditional E-value: 1.4e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +c+++l +H s v++la+ dg +++s+s D+++riW sp|Q12220|UTP12_YEAST 648 ECIQKLYAHqSEVWALAVATDGGFVVSSSHDHSIRIW 684 799******777**************9999******* PP >> sp|P25635|PWP2_YEAST Periodic tryptophan protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 0.17 10 12 37 .. 95 122 .. 87 123 .. 0.64 2 ! 20.5 0.8 3.5e-06 0.00021 8 38 .] 143 174 .. 137 174 .. 0.90 3 ! 9.7 0.0 0.0095 0.57 6 37 .. 186 218 .. 183 219 .. 0.92 4 ? 6.2 0.0 0.12 7.1 7 38 .] 256 288 .. 249 288 .. 0.78 5 ? 3.7 0.0 0.7 42 8 29 .. 299 321 .. 292 329 .. 0.82 6 ! 26.5 0.0 4.5e-08 2.7e-06 8 38 .] 342 373 .. 334 373 .. 0.88 7 ! 23.3 0.0 4.6e-07 2.8e-05 3 38 .] 379 415 .. 377 415 .. 0.95 8 ! 13.5 0.0 0.00057 0.034 3 38 .] 421 459 .. 419 459 .. 0.89 9 ! 35.2 0.1 8.3e-11 5e-09 1 38 [] 463 501 .. 463 501 .. 0.94 10 ? 1.8 0.0 2.9 1.7e+02 14 38 .] 581 605 .. 570 605 .. 0.87 11 ? 1.2 0.0 4.4 2.6e+02 13 29 .. 681 697 .. 670 708 .. 0.86 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.17 S...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvriW 37 + ++++fspdg+++a +s + + iW sp|P25635|PWP2_YEAST 95 FkekCSAVKFSPDGRLFALAS-GRFLQIW 122 34457899********76345.5555555 PP == domain 2 score: 20.5 bits; conditional E-value: 3.5e-06 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH +++tsl +s+d++++++ s+D + +iW+ sp|P25635|PWP2_YEAST 143 AGHfQDITSLTWSQDSRFILTTSKDLSAKIWS 174 49*999*************************5 PP == domain 3 score: 9.7 bits; conditional E-value: 0.0095 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 t+ GH + v + fs+d+ + + s+Dg v +W sp|P25635|PWP2_YEAST 186 TFNGHrDYVMGAFFSHDQEKIYTVSKDGAVFVW 218 899**888*9999******************** PP == domain 4 score: 6.2 bits; conditional E-value: 0.12 EESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss..vtslafspdgawlasGsdDgtvriWd 38 + + v ++ f+p ++la G g r++d sp|P25635|PWP2_YEAST 256 FYAN-QakVKCVTFHPATRLLAVGFTSGEFRLYD 288 3344.1459***************7799999998 PP == domain 5 score: 3.7 bits; conditional E-value: 0.7 E.SSSSEEEEEEETTSSEEEEEE CS WD40 8 t.GHssvtslafspdgawlasGs 29 + G+++v+ +++++ g wla Gs sp|P25635|PWP2_YEAST 299 SmGQNPVNTVSVNQTGEWLAFGS 321 448899*************8665 PP == domain 6 score: 26.5 bits; conditional E-value: 4.5e-08 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 GH +s +sla+spdg+ ++++s+Dg++++Wd sp|P25635|PWP2_YEAST 342 QGHfDSTNSLAYSPDGSRVVTASEDGKIKVWD 373 4997779************************9 PP == domain 7 score: 23.3 bits; conditional E-value: 4.6e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 cl t++ H ssvt+++f + g+ ++s+s Dgtvr Wd sp|P25635|PWP2_YEAST 379 CLATFEEHtSSVTAVQFAKRGQVMFSSSLDGTVRAWD 415 99******999*************************9 PP == domain 8 score: 13.5 bits; conditional E-value: 0.00057 EEEEEESSSSE..EEEEEETTSSEEEEEE.TTSEEEEEE CS WD40 3 clrtltGHssv..tslafspdgawlasGs.dDgtvriWd 38 + rt+tG + ++la++p+g +++Gs d+ +++W+ sp|P25635|PWP2_YEAST 421 NFRTFTGTERIqfNCLAVDPSGEVVCAGSlDNFDIHVWS 459 78999999778779**************98899999995 PP == domain 9 score: 35.2 bits; conditional E-value: 8.3e-11 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 gq+l l+GH ++v++l+fs++++ las+s+D+t+riW+ sp|P25635|PWP2_YEAST 463 GQLLDALSGHeGPVSCLSFSQENSVLASASWDKTIRIWS 501 5788899***999*************************5 PP == domain 10 score: 1.8 bits; conditional E-value: 2.9 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 t + +s dg +++G+ ++++ ++d sp|P25635|PWP2_YEAST 581 TTIHYSFDGMAIVAGGNNNSICLYD 605 56778889999999********998 PP == domain 11 score: 1.2 bits; conditional E-value: 4.4 EEEEEEETTSSEEEEEE CS WD40 13 vtslafspdgawlasGs 29 vts++fsp + +a++s sp|P25635|PWP2_YEAST 681 VTSVQFSPTANAFAAAS 697 9********99998877 PP >> sp|Q05946|UTP13_YEAST U3 small nucleolar RNA-associated protein 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 3.5 2.1e+02 12 25 .. 61 76 .. 50 81 .. 0.73 2 ? 3.4 0.0 0.92 55 18 36 .. 110 128 .. 82 130 .. 0.64 3 ! 19.0 0.4 1.1e-05 0.00066 4 38 .] 137 176 .. 134 176 .. 0.78 4 ! 18.5 0.0 1.5e-05 0.00089 1 38 [] 180 224 .. 180 224 .. 0.81 5 ! 16.6 0.0 6.2e-05 0.0037 6 37 .. 383 415 .. 380 416 .. 0.91 6 ? 3.0 0.0 1.2 74 6 37 .. 429 466 .. 425 466 .. 0.71 7 ! 28.0 0.0 1.5e-08 9e-07 8 38 .] 488 519 .. 481 519 .. 0.87 8 ! 20.0 0.1 5e-06 0.0003 5 38 .] 527 561 .. 523 561 .. 0.84 9 ! 22.9 0.0 6.3e-07 3.8e-05 3 38 .] 567 603 .. 565 603 .. 0.88 10 ! 19.9 0.1 5.7e-06 0.00034 1 38 [] 607 645 .. 607 645 .. 0.94 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 3.5 S..EEEEEEETTSSEE CS WD40 12 s..vtslafspdgawl 25 +t+l+ pdg++l sp|Q05946|UTP13_YEAST 61 EqeITALKLTPDGQYL 76 145************8 PP == domain 2 score: 3.4 bits; conditional E-value: 0.92 EETTSSEEEEEETTSEEEE CS WD40 18 fspdgawlasGsdDgtvri 36 ++ +++la G+ Dg++ + sp|Q05946|UTP13_YEAST 110 ADSTSTLLAVGGTDGSIIV 128 4556666999999***976 PP == domain 3 score: 19.0 bits; conditional E-value: 1.1e-05 EEEEESS.SSEEEEE...EETTSSE.EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla...fspdgaw.lasGsdDgtvriWd 38 +++++GH + ++sl+ ++ w lasG+ +g v++Wd sp|Q05946|UTP13_YEAST 137 THSFKGHgGTISSLKfygQLNSKIWlLASGDTNGMVKVWD 176 799****666****866666666665567777*******9 PP == domain 4 score: 18.5 bits; conditional E-value: 1.5e-05 TEEEEEEESS.SSEEEEE.......EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla.......fspdgawlasGsdDgtvriWd 38 ++cl+tl H s v++l+ p+ + l+sG++D + +Wd sp|Q05946|UTP13_YEAST 180 RKCLHTLQEHtSAVRGLDiievpdnDEPSLN-LLSGGRDDIINLWD 224 58********777****99988654444444.569**********9 PP == domain 5 score: 16.6 bits; conditional E-value: 6.2e-05 EEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHss.vtslafspdgawlasGsdDgtvriW 37 +++GH + +sl+ dg w+a++s+D+t +W sp|Q05946|UTP13_YEAST 383 IYEGHEDlLNSLDATEDGLWIATASKDNTAIVW 415 799**7757************************ PP == domain 6 score: 3.0 bits; conditional E-value: 1.2 EEESS.SSEEEEE.....EETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtsla.....fspdgawlasGsdDgtvriW 37 ++ GH vt++ + +l+++s D t++ W sp|Q05946|UTP13_YEAST 429 KYIGHsAAVTAVGlpnivSKGYPEFLLTASNDLTIKKW 466 588**555999966666555555558889989999877 PP == domain 7 score: 28.0 bits; conditional E-value: 1.5e-08 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +H +++++l++sp+ + +a++s+D+t++iW+ sp|Q05946|UTP13_YEAST 488 HAHeKDINALSVSPNDSIFATASYDKTCKIWN 519 288999*************************8 PP == domain 8 score: 20.0 bits; conditional E-value: 5e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl H + ++++f+++ ++la++s D+tv+iW+ sp|Q05946|UTP13_YEAST 527 ATLANHkRGLWDVSFCQYDKLLATSSGDKTVKIWS 561 5777895559*************9978*******5 PP == domain 9 score: 22.9 bits; conditional E-value: 6.3e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++tl+GH + v ++f ++ l+s++ Dg ++iWd sp|Q05946|UTP13_YEAST 567 VMKTLEGHtNAVQRCSFINKQKQLISCGADGLIKIWD 603 5799****999*99998888888888988*******9 PP == domain 10 score: 19.9 bits; conditional E-value: 5.7e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+cl+tl+GH + ++l++ dg++++s++ Dg +W+ sp|Q05946|UTP13_YEAST 607 GECLKTLDGHnNRLWALSTMNDGDMIVSADADGVFQFWK 645 69********777****************99*****995 PP >> sp|P38011|GBLP_YEAST Guanine nucleotide-binding protein subunit beta-like protein OS=Saccharomyces cerevisiae (strai # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 1.8e-05 0.0011 5 37 .. 11 45 .. 8 46 .. 0.83 2 ! 30.9 0.3 1.8e-09 1.1e-07 2 38 .] 56 93 .. 55 93 .. 0.93 3 ! 26.2 0.1 5.5e-08 3.3e-06 5 37 .. 101 134 .. 97 135 .. 0.90 4 ! 15.1 0.1 0.00018 0.011 1 38 [] 138 182 .. 138 182 .. 0.85 5 ! 28.5 0.0 1.1e-08 6.4e-07 6 38 .] 191 224 .. 186 224 .. 0.90 6 ! 11.0 0.0 0.0035 0.21 4 29 .. 231 256 .. 228 264 .. 0.84 7 ! 18.2 0.0 1.8e-05 0.0011 13 37 .. 290 313 .. 280 314 .. 0.90 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 1.8e-05 EEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawla.sGsdDgtvriW 37 +tl+GH ++vtsla+s ++ l+ s+s+D+t+ W sp|P38011|GBLP_YEAST 11 GTLEGHnGWVTSLATSAGQPNLLlSASRDKTLISW 45 689***666*****88888886449*******999 PP == domain 2 score: 30.9 bits; conditional E-value: 1.8e-09 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++r+++GHs+ v ++ dga+ +s+s+D+t+r+Wd sp|P38011|GBLP_YEAST 56 VPVRSFKGHSHiVQDCTLTADGAYALSASWDKTLRLWD 93 689******8867***********99***********9 PP == domain 3 score: 26.2 bits; conditional E-value: 5.5e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 + + GH s+v s++ ++ ++++sGs+D+t+++W sp|P38011|GBLP_YEAST 101 QRFVGHkSDVMSVDIDKKASMIISGSRDKTIKVW 134 4578**888************************* PP == domain 4 score: 15.1 bits; conditional E-value: 0.00018 TEEEEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtsla......fspdgawlasGsdDgtvriWd 38 gqcl tl GH ++v+ ++ ++d+ ++s++ D+ v+ W+ sp|P38011|GBLP_YEAST 138 GQCLATLLGHnDWVSQVRvvpnekADDDSVTIISAGNDKMVKAWN 182 79********555999988888887777777999888*******8 PP == domain 5 score: 28.5 bits; conditional E-value: 1.1e-08 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + GH s+++ l spdg+++as+++Dg +++W+ sp|P38011|GBLP_YEAST 191 DFIGHnSNINTLTASPDGTLIASAGKDGEIMLWN 224 589**666*************************8 PP == domain 6 score: 11.0 bits; conditional E-value: 0.0035 EEEEESSSSEEEEEEETTSSEEEEEE CS WD40 4 lrtltGHssvtslafspdgawlasGs 29 ++tl++++ v slafsp+ wla+++ sp|P38011|GBLP_YEAST 231 MYTLSAQDEVFSLAFSPNRYWLAAAT 256 678999977*************9764 PP == domain 7 score: 18.2 bits; conditional E-value: 1.8e-05 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 v sla+s dg+ l++G D+ +r+W sp|P38011|GBLP_YEAST 290 V-SLAWSADGQTLFAGYTDNVIRVW 313 6.99************88******* PP >> sp|P41318|LST8_YEAST Target of rapamycin complex subunit LST8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.0 0.0069 0.42 25 37 .. 5 17 .. 2 18 .. 0.77 2 ? 9.5 0.0 0.011 0.63 2 38 .] 23 59 .. 22 59 .. 0.85 3 ! 41.7 0.1 7.4e-13 4.4e-11 2 38 .] 66 103 .. 65 103 .. 0.96 4 ! 20.4 0.0 3.8e-06 0.00023 8 38 .] 114 144 .. 108 144 .. 0.89 5 ? 7.7 0.0 0.039 2.3 2 37 .. 149 186 .. 148 187 .. 0.81 6 ! 22.9 0.1 6.1e-07 3.7e-05 2 38 .] 198 235 .. 197 235 .. 0.92 7 ! 33.6 0.7 2.5e-10 1.5e-08 3 38 .] 242 278 .. 240 278 .. 0.90 8 ? 1.9 0.0 2.7 1.6e+02 3 16 .. 284 298 .. 282 302 .. 0.76 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.0069 EEEEETTSEEEEE CS WD40 25 lasGsdDgtvriW 37 l+s+++D+t+r+W sp|P41318|LST8_YEAST 5 LVSAGYDHTIRFW 17 566777******* PP == domain 2 score: 9.5 bits; conditional E-value: 0.011 EEEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 c rt+ H +s v+ l d+++la+++ ++vr++d sp|P41318|LST8_YEAST 23 VCSRTI-QHsDSqVNRLEITNDKKLLATAG-HQNVRLYD 59 577887.595337*****************.*****998 PP == domain 3 score: 41.7 bits; conditional E-value: 7.4e-13 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +++GH ++vts++f++d++w++++s+Dgt+++Wd sp|P41318|LST8_YEAST 66 NPVASFEGHrGNVTSVSFQQDNRWMVTSSEDGTIKVWD 103 6899*****999*************************9 PP == domain 4 score: 20.4 bits; conditional E-value: 3.8e-06 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 + H +v+ + +p++ l+s+++Dg++riWd sp|P41318|LST8_YEAST 114 K-HnAPVNEVVIHPNQGELISCDRDGNIRIWD 144 4.7567*************************9 PP == domain 5 score: 7.7 bits; conditional E-value: 0.039 EEEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH..ssvtslafspdgawlasGsdDgtvriW 37 qc++ lt +s sl+ +dg++la++ +g++++W sp|P41318|LST8_YEAST 149 QCTHQLTPEddTSLQSLSMASDGSMLAAANTKGNCYVW 186 677777755334499999*********9977******* PP == domain 6 score: 22.9 bits; conditional E-value: 6.1e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++++++++H + +t + s+d + la++s D+t r+W+ sp|P41318|LST8_YEAST 198 KPVTKFRAHsTYITRILLSSDVKHLATCSADHTARVWS 235 68999****666*************************5 PP == domain 7 score: 33.6 bits; conditional E-value: 2.5e-10 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +tl+GH +v+++afs d+a+l+++s D+ vr+Wd sp|P41318|LST8_YEAST 242 LETTLDGHqRWVWDCAFSADSAYLVTASSDHYVRLWD 278 56799***777**************9988*******9 PP == domain 8 score: 1.9 bits; conditional E-value: 2.7 EEEEEESS.SS.EEEE CS WD40 3 clrtltGH.ss.vtsl 16 +r + GH ++ v ++ sp|P41318|LST8_YEAST 284 IVRQYGGHhKGaV-CV 298 68999***97767.88 PP >> sp|P53622|COPA_YEAST Coatomer subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CO # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.29 17 15 38 .] 16 39 .. 8 39 .. 0.90 2 ! 26.9 0.0 3.5e-08 2.1e-06 2 38 .] 44 81 .. 43 81 .. 0.94 3 ! 33.9 0.1 2e-10 1.2e-08 2 38 .] 86 123 .. 85 123 .. 0.97 4 ! 27.1 0.1 2.9e-08 1.7e-06 3 38 .] 129 165 .. 127 165 .. 0.91 5 ! 22.4 0.2 8.6e-07 5.2e-05 6 37 .. 204 236 .. 197 237 .. 0.87 6 ! 26.1 0.5 5.9e-08 3.5e-06 4 38 .] 246 281 .. 243 281 .. 0.93 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.29 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 ++af+p+ +w++ + t+ +Wd sp|P53622|COPA_YEAST 16 GIAFHPSRPWVLVALFSSTIQLWD 39 689*******999955*******9 PP == domain 2 score: 26.9 bits; conditional E-value: 3.5e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++l+ ++ H ++v++l+f+p ++ ++s++dD t+++W+ sp|P53622|COPA_YEAST 44 TLLHRFEDHeGPVRGLDFHPTQPIFVSAGDDYTIKVWS 81 68999****999***************9*********5 PP == domain 3 score: 33.9 bits; conditional E-value: 2e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl+tltGH + v+ + f+++ +w++s+sdD+t+riW+ sp|P53622|COPA_YEAST 86 KCLYTLTGHlDYVRTVFFHRELPWIISASDDQTIRIWN 123 8********999*************************8 PP == domain 4 score: 27.1 bits; conditional E-value: 2.9e-08 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 + ltGH++ v + +f+p ++++s+s D t+riWd sp|P53622|COPA_YEAST 129 EIACLTGHNHfVMCAQFHPTDDLIVSASLDETIRIWD 165 67789***777*************************9 PP == domain 5 score: 22.4 bits; conditional E-value: 8.6e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l+GH +v+ +f+p ++++sGsdD+ v++W sp|P53622|COPA_YEAST 204 ILEGHtRGVNWASFHPTLPLIVSGSDDRQVKLW 236 578**666************************* PP == domain 6 score: 26.1 bits; conditional E-value: 5.9e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + t++GH ++v s+ f+p++++++s ++D+t+r+Wd sp|P53622|COPA_YEAST 246 VDTCRGHtNNVDSVIFHPHQNLIISVGEDKTLRVWD 281 6799***999**************9999*******9 PP >> sp|P42935|ELP2_YEAST Elongator complex protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.3 0.0 7.5e-11 4.5e-09 6 38 .] 54 87 .. 51 87 .. 0.94 2 ! 10.0 0.1 0.0077 0.46 2 37 .. 95 129 .. 94 130 .. 0.68 3 ! 18.0 0.0 2.3e-05 0.0014 4 37 .. 195 233 .. 192 234 .. 0.77 4 ! 11.0 0.0 0.0037 0.22 9 37 .. 279 308 .. 271 309 .. 0.84 5 ! 16.3 0.0 7.5e-05 0.0045 8 36 .. 382 411 .. 376 412 .. 0.86 6 ! 17.2 0.0 3.9e-05 0.0023 6 32 .. 553 580 .. 547 591 .. 0.78 7 ! 12.6 0.0 0.0011 0.067 10 37 .. 605 633 .. 599 634 .. 0.84 8 ! 10.6 0.1 0.0048 0.29 23 37 .. 660 682 .. 646 683 .. 0.72 Alignments for each domain: == domain 1 score: 35.3 bits; conditional E-value: 7.5e-11 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 tl+GH vt+++f pd+++++s+s+D++v+iW+ sp|P42935|ELP2_YEAST 54 TLKGHeAEVTCVRFVPDSDFMVSASEDHHVKIWK 87 89***877*************************6 PP == domain 2 score: 10.0 bits; conditional E-value: 0.0077 EEEEEEESS..SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH..ssvtslafspdgawlasGsdDgtvriW 37 qc++t+ H + + +l s ++++ G+ Dgt+ iW sp|P42935|ELP2_YEAST 95 QCIQTI-QHysKTIVAL--SALPSLISVGCADGTISIW 129 677776.4764446666..444555777999******* PP == domain 3 score: 18.0 bits; conditional E-value: 2.3e-05 EEEEESS.SSEEEEE...EETTSSE.EEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla...fspdgaw.lasGsdDgtvriW 37 + +l+GH ++v sla g++ l+sGs D+ +r+W sp|P42935|ELP2_YEAST 195 VAELEGHeDWVKSLAfrhQETPGDYlLCSGSQDRYIRLW 233 67899**888****8888444444435799********* PP == domain 4 score: 11.0 bits; conditional E-value: 0.0037 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 GH ++++sl+++ + l++++ D ++++W sp|P42935|ELP2_YEAST 279 GHdDWISSLQWHESRLQLLAATADTSLMVW 308 9*777****88888777988988******* PP == domain 5 score: 16.3 bits; conditional E-value: 7.5e-05 ESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvri 36 +G ++vt++a+sp+g +l++ s D+t r+ sp|P42935|ELP2_YEAST 382 SGAtKDVTDIAWSPSGEYLLATSLDQTTRL 411 577789************998899**9998 PP == domain 6 score: 17.2 bits; conditional E-value: 3.9e-05 EEESS.SSEEEEEEETTSSEEEEEETTS CS WD40 6 tltGH.ssvtslafspdgawlasGsdDg 32 +l GH + +t+l+ spd++++as+++ + sp|P42935|ELP2_YEAST 553 KLYGHgFEITCLDISPDQKLIASACRSN 580 578**666**************987633 PP == domain 7 score: 12.6 bits; conditional E-value: 0.0011 SSS..EEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 Hss..vtslafspdgawlasGsdDgtvriW 37 H s +t l+fs+dg++l+s ++D++ +W sp|P42935|ELP2_YEAST 605 H-SltITRLKFSKDGKFLLSVCRDRKWALW 633 6.334**************9999**99888 PP == domain 8 score: 10.6 bits; conditional E-value: 0.0048 SE........EEEEETTSEEEEE CS WD40 23 aw........lasGsdDgtvriW 37 +w ++++s+D+tv++W sp|P42935|ELP2_YEAST 660 DWaplefgnvFVTASRDKTVKVW 682 45555555547899********* PP >> sp|P07834|CDC4_YEAST Cell division control protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 7.9e-07 4.7e-05 5 38 .] 375 408 .. 371 408 .. 0.86 2 ! 26.6 0.3 4.2e-08 2.5e-06 4 38 .] 415 449 .. 412 449 .. 0.88 3 ! 26.2 0.6 5.6e-08 3.4e-06 1 38 [] 453 493 .. 453 493 .. 0.84 4 ! 21.9 0.4 1.3e-06 7.9e-05 4 38 .] 523 556 .. 521 556 .. 0.95 5 ! 22.5 0.1 8.5e-07 5.1e-05 2 38 .] 561 598 .. 560 598 .. 0.90 6 ? 8.9 0.0 0.017 1 5 38 .] 626 658 .. 623 658 .. 0.77 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 7.9e-07 EEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 +tl+GH +s +t+l + + +++++G dD+ +r++d sp|P07834|CDC4_YEAST 375 TTLRGHmTSvITCL--QFEDNYVITGADDKMIRVYD 408 469****9956***..77888899**********98 PP == domain 2 score: 26.6 bits; conditional E-value: 4.2e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l l+GH ++v++l++ + g ++ sGs D+tvr+Wd sp|P07834|CDC4_YEAST 415 LLQLSGHdGGVWALKYAHGGILV-SGSTDRTVRVWD 449 66799**877****999999996.8*99*******9 PP == domain 3 score: 26.2 bits; conditional E-value: 5.6e-08 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 g c+++++GH s v++l+ +++ +++Gs+D+t+++W+ sp|P07834|CDC4_YEAST 453 GCCTHVFKGHnSTVRCLDIVEYKNIkyIVTGSRDNTLHVWK 493 579*******655****866666667799***********6 PP == domain 4 score: 21.9 bits; conditional E-value: 1.3e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++l+GH sv+ + s +g+ ++sGs+D+t+ +Wd sp|P07834|CDC4_YEAST 523 VGVLRGHmASVRTV--SGHGNIVVSGSYDNTLIVWD 556 6799**********..*******************9 PP == domain 5 score: 22.5 bits; conditional E-value: 8.5e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl++l+GH + ++s ++++ + +s+s+D t+riWd sp|P07834|CDC4_YEAST 561 KCLYILSGHtDRIYSTIYDHERKRCISASMDTTIRIWD 598 8********666*99989999999999999*******9 PP == domain 6 score: 8.9 bits; conditional E-value: 0.017 EEEESSSS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGHss...vtslafspdgawlasGsdDgtvriWd 38 +tl GH+ l + ++l+s+ Dg++r Wd sp|P07834|CDC4_YEAST 626 YTLQGHTAlvgLLRL----SDKFLVSAAADGSIRGWD 658 689999555334677....7888999988*******8 PP >> sp|P41811|COPB2_YEAST Coatomer subunit beta' OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.014 0.84 11 38 .] 13 41 .. 4 41 .. 0.83 2 ? 6.7 0.0 0.085 5.1 21 38 .] 66 83 .. 47 83 .. 0.84 3 ! 26.4 0.0 5e-08 3e-06 4 38 .] 90 125 .. 87 125 .. 0.90 4 ! 24.4 0.0 2.1e-07 1.2e-05 4 38 .] 133 169 .. 130 169 .. 0.85 5 ! 13.9 0.0 0.00042 0.025 13 38 .] 187 214 .. 174 214 .. 0.79 6 ! 29.4 0.0 5.4e-09 3.2e-07 2 38 .] 219 256 .. 218 256 .. 0.91 7 ? 1.9 0.0 2.7 1.6e+02 14 32 .. 360 377 .. 349 382 .. 0.81 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.014 SS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ss.vtslafspdgawlasGsdDgtvriWd 38 s+ v +++f+p +w+++ + g v +W+ sp|P41811|COPB2_YEAST 13 SDrVKGIDFHPTEPWVLTTLYSGRVELWN 41 44699************9977*******8 PP == domain 2 score: 6.7 bits; conditional E-value: 0.085 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 ++w++ GsdD +r+++ sp|P41811|COPB2_YEAST 66 RKNWIIVGSDDFRIRVFN 83 579*************97 PP == domain 3 score: 26.4 bits; conditional E-value: 5e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++H + ++s+a++p +++++sGsdD tv++W+ sp|P41811|COPB2_YEAST 90 VVDFEAHpDYIRSIAVHPTKPYVLSGSDDLTVKLWN 125 56699**777*************************8 PP == domain 4 score: 24.4 bits; conditional E-value: 2.1e-07 EEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +t++GH +v ++af+p + +asG+ D+tv++W+ sp|P41811|COPB2_YEAST 133 EQTFEGHeHFVMCVAFNPKDPStFASGCLDRTVKVWS 169 689****666*****8888888799***********5 PP == domain 5 score: 13.9 bits; conditional E-value: 0.00042 EEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 13 vtsla..fspdgawlasGsdDgtvriWd 38 v+ ++ pd+++++++sdD t++iWd sp|P41811|COPB2_YEAST 187 VNYVDyyPLPDKPYMITASDDLTIKIWD 214 666666678******************9 PP == domain 6 score: 29.4 bits; conditional E-value: 5.4e-09 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +c+ tl+GH s+v s+a f+p + ++sGs+Dgt++iW+ sp|P41811|COPB2_YEAST 219 SCVATLEGHmSNV-SFAvFHPTLPIIISGSEDGTLKIWN 256 79*******999*.5555********************8 PP == domain 7 score: 1.9 bits; conditional E-value: 2.7 EEEEEETTSSEEEEEETTS CS WD40 14 tslafspdgawlasGsdDg 32 sla sp+g++++ + Dg sp|P41811|COPB2_YEAST 360 QSLAHSPNGRFVTVVG-DG 377 5899*******97666.66 PP >> sp|P39014|MET30_YEAST F-box protein MET30 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MET3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 3.1e-05 0.0018 4 38 .] 295 328 .. 293 328 .. 0.91 2 ! 22.1 0.1 1.1e-06 6.7e-05 1 38 [] 332 368 .. 332 368 .. 0.81 3 ! 28.6 0.7 1e-08 6e-07 1 37 [. 372 407 .. 372 408 .. 0.93 4 ! 25.9 1.0 6.9e-08 4.2e-06 5 38 .] 415 449 .. 411 449 .. 0.91 5 ? 3.8 0.0 0.68 41 2 15 .. 454 468 .. 453 502 .. 0.77 6 ! 11.4 0.0 0.0026 0.15 20 38 .] 520 538 .. 504 538 .. 0.86 7 ! 20.4 1.0 3.9e-06 0.00024 1 38 [] 542 578 .. 542 578 .. 0.84 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 3.1e-05 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++GH ++v l + + ++l++Gs+D t+ iWd sp|P39014|MET30_YEAST 295 IQEFKGHmDGVLTL--QFNYRLLFTGSYDSTIGIWD 328 5789***999*999..778899*************9 PP == domain 2 score: 22.1 bits; conditional E-value: 1.1e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+++r l+GH ++v l + d + l++Gs D+t+r+W+ sp|P39014|MET30_YEAST 332 GKLIRRLSGHsDGVKTL-YF-DDRKLITGSLDKTIRVWN 368 678999****666**99.44.4445669**********8 PP == domain 3 score: 28.6 bits; conditional E-value: 1e-08 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 g+c+ t++GH +sv s+ +++++ ++sGs D+tv++W sp|P39014|MET30_YEAST 372 GECISTYRGHsDSVLSV--DSYQKVIVSGSADKTVKVW 407 68********777****..999999************* PP == domain 4 score: 25.9 bits; conditional E-value: 6.9e-08 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +tl+GH +v++++ +p + +s+sdD t+r+Wd sp|P39014|MET30_YEAST 415 YTLRGHtEWVNCVKLHPKSFSCFSCSDDTTIRMWD 449 799***888*****999999999***********9 PP == domain 5 score: 3.8 bits; conditional E-value: 0.68 EEEEEEESS.SSEEE CS WD40 2 qclrtltGH.ssvts 15 +cl++++GH + v sp|P39014|MET30_YEAST 454 SCLKVFRGHvGQVQK 468 79*******666543 PP == domain 6 score: 11.4 bits; conditional E-value: 0.0026 TTSSEEEEEETTSEEEEEE CS WD40 20 pdgawlasGsdDgtvriWd 38 p+ + l+s++ D+t+++Wd sp|P39014|MET30_YEAST 520 PYPTHLLSCGLDNTIKLWD 538 55566788999*******9 PP == domain 7 score: 20.4 bits; conditional E-value: 3.9e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+c+rt GH +v+++ d+ ++sGs Dg++++Wd sp|P39014|MET30_YEAST 542 GKCIRTQFGHvEGVWDI--AADNFRIISGSHDGSIKVWD 578 68999977**8889999..55555588**99*******9 PP >> sp|Q05583|CIAO1_YEAST Cytosolic iron-sulfur protein assembly protein 1 OS=Saccharomyces cerevisiae (strain ATCC 2045 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.061 3.7 14 36 .. 18 38 .. 4 40 .. 0.73 2 ! 22.8 0.2 6.7e-07 4e-05 8 37 .. 55 85 .. 47 85 .. 0.92 3 ! 31.3 0.0 1.3e-09 8.1e-08 3 37 .. 99 134 .. 97 135 .. 0.93 4 ! 30.6 0.2 2.3e-09 1.4e-07 2 38 .] 144 181 .. 143 181 .. 0.95 5 ! 22.2 1.1 1e-06 6.1e-05 1 38 [] 187 227 .. 187 227 .. 0.87 6 ? 2.9 0.0 1.3 79 9 36 .. 248 275 .. 239 277 .. 0.71 7 ! 9.9 0.1 0.0079 0.47 23 38 .] 310 325 .. 291 325 .. 0.77 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.061 EEEEEETTSSEEEEEETTSEEEE CS WD40 14 tslafspdgawlasGsdDgtvri 36 +s f+ ++ la+Gs D+++++ sp|Q05583|CIAO1_YEAST 18 WS--FDFSQGILATGSTDRKIKL 38 33..45666669*********97 PP == domain 2 score: 22.8 bits; conditional E-value: 6.7e-07 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 t+H + ++s+a+ p+ ++la+Gs D tv iW sp|Q05583|CIAO1_YEAST 55 TAHkKAIRSVAWRPHTSLLAAGSFDSTVSIW 85 59*888************************* PP == domain 3 score: 31.3 bits; conditional E-value: 1.3e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +l +++GH + v ++a+s dg +la++s+D++v iW sp|Q05583|CIAO1_YEAST 99 LLAIIEGHeNEVKGVAWSNDGYYLATCSRDKSVWIW 134 678899**999************************* PP == domain 4 score: 30.6 bits; conditional E-value: 2.3e-09 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ +l H ++v ++ ++p+ a+las+s+D tvriW+ sp|Q05583|CIAO1_YEAST 144 ECISVLQEHsQDVKHVIWHPSEALLASSSYDDTVRIWK 181 799******888*************************6 PP == domain 5 score: 22.2 bits; conditional E-value: 1e-06 TEEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgaw..lasGsdDgtvriWd 38 ++c+ +l GH + v+s +f++ l+sGsdD tvr+W+ sp|Q05583|CIAO1_YEAST 187 WECVAVLNGHeGTVWSSDFDKTEGVfrLCSGSDDSTVRVWK 227 68********888****777777778889***********6 PP == domain 6 score: 2.9 bits; conditional E-value: 1.3 SSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvri 36 H+ v+ +a+ +g + G Dg + + sp|Q05583|CIAO1_YEAST 248 VHKRqVYNVAWGFNGLIASVGA-DGVLAV 275 68445999*8888888866666.*98766 PP == domain 7 score: 9.9 bits; conditional E-value: 0.0079 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 + la+G+dDg v +W+ sp|Q05583|CIAO1_YEAST 310 TILATGGDDGIVNFWS 325 3389***********5 PP >> sp|P47025|MDV1_YEAST Mitochondrial division protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.3 1.5e-05 0.0009 6 38 .] 393 427 .. 388 427 .. 0.74 2 ! 18.8 0.0 1.2e-05 0.00071 2 38 .] 432 469 .. 431 469 .. 0.93 3 ! 29.4 0.1 5.7e-09 3.4e-07 3 38 .] 494 528 .. 492 528 .. 0.92 4 ! 11.4 0.0 0.0027 0.16 21 38 .] 576 592 .. 557 592 .. 0.83 5 ! 33.5 0.2 2.8e-10 1.7e-08 1 38 [] 596 632 .. 596 632 .. 0.89 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 1.5e-05 EEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 + ++H ++ t+l+ p g++ ++G D+tv+iWd sp|P47025|MDV1_YEAST 393 IMSTHdDFLTCLDfDAPFGTLCTAGYLDHTVKIWD 427 5689*6669***855555555556777*******9 PP == domain 2 score: 18.8 bits; conditional E-value: 1.2e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++l GH +++++ ++d l++G++D +++W+ sp|P47025|MDV1_YEAST 432 NKIGELAGHlATINCMQINRDYGTLVTGGRDAALKLWN 469 5678999**999*************************8 PP == domain 3 score: 29.4 bits; conditional E-value: 5.7e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 c++t+++H + vt+l s d ++l+sGs D+t+r Wd sp|P47025|MDV1_YEAST 494 CVHTFEAHtDEVTAL--SLDPSFLVSGSQDRTIRQWD 528 9*******666**99..889999*************9 PP == domain 4 score: 11.4 bits; conditional E-value: 0.0027 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 d a la+G++Dg vr+Wd sp|P47025|MDV1_YEAST 576 DAA-LATGTKDGVVRLWD 592 444.589**********9 PP == domain 5 score: 33.5 bits; conditional E-value: 2.8e-10 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+ +rtl+GH + +tsl d+a l++Gs+D+tvriWd sp|P47025|MDV1_YEAST 596 GKVIRTLKGHtDAITSL--KFDSACLVTGSYDRTVRIWD 632 5789******666****..559999*************9 PP >> sp|P20053|PRP4_YEAST U4/U6 small nuclear ribonucleoprotein PRP4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.1 5.2 3.1e+02 11 30 .. 176 195 .. 169 201 .. 0.82 2 ! 10.1 0.0 0.0071 0.42 5 35 .. 212 244 .. 207 246 .. 0.86 3 ! 20.4 0.2 3.7e-06 0.00022 3 38 .] 257 293 .. 255 293 .. 0.84 4 ! 19.6 0.0 7e-06 0.00042 8 38 .] 304 335 .. 298 335 .. 0.92 5 ! 32.1 0.1 7.5e-10 4.5e-08 2 38 .] 340 377 .. 339 377 .. 0.93 6 ? 5.3 0.0 0.22 13 5 37 .. 388 422 .. 384 423 .. 0.70 7 ! 28.9 1.4 8e-09 4.8e-07 4 38 .] 430 465 .] 427 465 .] 0.89 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 5.2 SSEEEEEEETTSSEEEEEET CS WD40 11 ssvtslafspdgawlasGsd 30 +++++++ s d +a+Gs+ sp|P20053|PRP4_YEAST 176 KPISAVSLSTDDMVVATGSW 195 56999999999999****97 PP == domain 2 score: 10.1 bits; conditional E-value: 0.0071 EEEESS.SSEEEEEEETTSSE.EEEEETTSEEE CS WD40 5 rtltGH.ssvtslafspdgaw.lasGsdDgtvr 35 ++l+ H + + +++++pd++ ++s+ +Dg ++ sp|P20053|PRP4_YEAST 212 QKLDSHvGKIGAIDWHPDSNNqMISCAEDGLIK 244 568899888************9789999**997 PP == domain 3 score: 20.4 bits; conditional E-value: 3.7e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+ l GH +++++++p+g+++ s+s D t r+Wd sp|P20053|PRP4_YEAST 257 LLGDLVGHeRRISDVKYHPSGKFIGSASHDMTWRLWD 293 577889**666************945566*******9 PP == domain 4 score: 19.6 bits; conditional E-value: 7e-06 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 +GH ++v sl+f+ dg++++sG++D ++Wd sp|P20053|PRP4_YEAST 304 EGHdKGVFSLSFQCDGSLVCSGGMDSLSMLWD 335 5**999*************************9 PP == domain 5 score: 32.1 bits; conditional E-value: 7.5e-10 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ tl GH ++++ +a+sp+g +a+G+ Dg + +Wd sp|P20053|PRP4_YEAST 340 SKVMTLAGHsKPIYTVAWSPNGYQVATGGGDGIINVWD 377 67899****999****************88*******9 PP == domain 6 score: 5.3 bits; conditional E-value: 0.22 EEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw..lasGsdDgtvriW 37 ++l +H + vt ++fs++ l+s+++D+ + ++ sp|P20053|PRP4_YEAST 388 QIL-AHrNIVTQVRFSKEDGGkkLVSCGYDNLINVY 422 555.7988899997554444466889999*999887 PP == domain 7 score: 28.9 bits; conditional E-value: 8e-09 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 +++l GH++ + sl+ s ++++l+sG++D+++++W+ sp|P20053|PRP4_YEAST 430 MGSLAGHTDkIISLDISNNSHFLVSGGWDRSIKLWN 465 67899**44577***********************8 PP >> sp|P36037|DOA1_YEAST Protein DOA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DOA1 PE=1 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.1 4.1e-06 0.00024 2 38 .] 4 40 .. 3 40 .. 0.80 2 ? 3.4 0.0 0.88 53 6 34 .. 50 78 .. 46 79 .. 0.86 3 ! 22.8 0.2 6.9e-07 4.1e-05 2 38 .] 90 125 .. 89 125 .. 0.81 4 ! 16.2 0.0 8.3e-05 0.0049 2 37 .. 128 165 .. 127 166 .. 0.77 5 ! 11.6 0.7 0.0023 0.14 4 36 .. 171 204 .. 168 206 .. 0.80 6 ! 35.7 0.0 5.7e-11 3.4e-09 2 38 .] 211 247 .. 210 247 .. 0.91 7 ? 7.6 0.2 0.044 2.6 12 37 .. 263 287 .. 254 288 .. 0.86 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 4.1e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q+ tl+GH ++v+++ + d + +as s+Dgtvr+W+ sp|P36037|DOA1_YEAST 4 QLSATLKGHdQDVRDV-VAVDDSKVASVSRDGTVRLWS 40 56789****8888888.4446666788899*******5 PP == domain 2 score: 3.4 bits; conditional E-value: 0.88 EEESSSSEEEEEEETTSSEEEEEETTSEE CS WD40 6 tltGHssvtslafspdgawlasGsdDgtv 34 ++tG+++ +s+++++++ +l+ G++D + sp|P36037|DOA1_YEAST 50 VYTGQGFLNSVCYDSEKELLLFGGKDTMI 78 5899988************9889999766 PP == domain 3 score: 22.8 bits; conditional E-value: 6.9e-07 EEEEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 ++l+tl GH ++v+sl ++ ++sGs+D+t ++W+ sp|P36037|DOA1_YEAST 90 DPLYTLIGHqGNVCSL------SFqdgvVISGSWDKTAKVWK 125 6899*****777****......444443679**********6 PP == domain 4 score: 16.2 bits; conditional E-value: 8.3e-05 EEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgawlasGsdDgtvriW 37 ++++ l +H sv++ + +++++l ++s D+t+++W sp|P36037|DOA1_YEAST 128 SLVYNLQAHnASVWDAKvvSFSENKFL-TASADKTIKLW 165 6788899**777*99999555666665.6777******* PP == domain 5 score: 11.6 bits; conditional E-value: 0.0023 EEEEE.SSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 4 lrtlt.GHss.vtslafspdgawlasGsdDgtvri 36 ++t++ H++ v++la+ +dg+++ s+s Dg +++ sp|P36037|DOA1_YEAST 171 IKTFSgIHNDvVRHLAVVDDGHFI-SCSNDGLIKL 204 567763469966***********8.6888****98 PP == domain 6 score: 35.7 bits; conditional E-value: 5.7e-11 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + lrt++GH s+v++++ p+g+ + s+++D+tvriW+ sp|P36037|DOA1_YEAST 211 DVLRTYEGHeSFVYCIKLLPNGDIV-SCGEDRTVRIWS 247 679******999************8.6788*******5 PP == domain 7 score: 7.6 bits; conditional E-value: 0.044 SEEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriW 37 s++s++ ++g+ ++ Gs D+ vri+ sp|P36037|DOA1_YEAST 263 SIWSVDCMSNGDIIV-GSSDNLVRIF 287 4899*********98.877*****97 PP >> sp|Q12417|PRP46_YEAST Pre-mRNA-splicing factor PRP46 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 1.2 2.8e-07 1.7e-05 2 38 .] 130 168 .. 129 168 .. 0.94 2 ! 21.1 0.1 2.3e-06 0.00014 2 38 .] 173 210 .. 172 210 .. 0.92 3 ! 25.0 0.1 1.3e-07 8.1e-06 2 38 .] 215 252 .. 214 252 .. 0.94 4 ! 20.0 0.0 5.2e-06 0.00031 3 38 .] 258 294 .. 256 294 .. 0.87 5 ? 1.5 0.0 3.5 2.1e+02 1 31 [. 298 329 .. 298 334 .. 0.71 6 ? 4.1 0.0 0.54 32 12 38 .] 351 377 .. 339 377 .. 0.73 7 ! 12.6 0.0 0.0012 0.069 4 38 .] 393 427 .. 380 427 .. 0.82 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 2.8e-07 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 ++ r++ GH ++v+++a + d+ w+++Gs D t ++Wd sp|Q12417|PRP46_YEAST 130 KLSRVINGHlGWVRCVAiDPVDNEWFITGSNDTTMKVWD 168 7789999***********999*****************9 PP == domain 2 score: 21.1 bits; conditional E-value: 2.3e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +tl GH v+++a+s+ +++l+s s+D+tv+ Wd sp|Q12417|PRP46_YEAST 173 KLKTTLAGHvMTVRDVAVSDRHPYLFSVSEDKTVKCWD 210 6678999**8889*************99*********9 PP == domain 3 score: 25.0 bits; conditional E-value: 1.3e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 q +r + GH s+v+ ++ +p +++a++++D +++Wd sp|Q12417|PRP46_YEAST 215 QIIRDYYGHlSGVRTVSIHPTLDLIATAGRDSVIKLWD 252 6688999******************************9 PP == domain 4 score: 20.0 bits; conditional E-value: 5.2e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ tl GH ++++ ++ p + ++s+s D tvr+Wd sp|Q12417|PRP46_YEAST 258 PVITLVGHkGPINQVQCTPVDPQVVSSSTDATVRLWD 294 678999**777****98888888889989*******9 PP == domain 5 score: 1.5 bits; conditional E-value: 3.5 TEEEEEEESS.SSEEEEEEETTSSEEEEEETT CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdD 31 g+++++lt H sv++ a +p +as++ D sp|Q12417|PRP46_YEAST 298 GKTMKVLTHHkRSVRATALHPKEFSVASACTD 329 57889999996669777768877778766533 PP == domain 6 score: 4.1 bits; conditional E-value: 0.54 S.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s.vtslafspdgawlasGsdDgtvriWd 38 + ++ l+ ++d ++a G+d+g + ++d sp|Q12417|PRP46_YEAST 351 GiINTLSINQDDVLFA-GGDNGVLSFYD 377 3479999999999986.99999998887 PP == domain 7 score: 12.6 bits; conditional E-value: 0.0012 EEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHssvtslafspdgawlasGsdDgtvriWd 38 +++l+G sv + f++ g l++G D++++iW+ sp|Q12417|PRP46_YEAST 393 VGSLEGERSVLCSTFDKTGLRLITGEADKSIKIWK 427 4556666557788899*********77*******6 PP >> sp|P42841|PFS2_YEAST Polyadenylation factor subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 1.2 74 10 38 .] 86 121 .. 80 121 .. 0.71 2 ! 27.8 0.1 1.7e-08 1e-06 8 37 .. 132 162 .. 124 163 .. 0.89 3 ! 22.4 0.1 8.8e-07 5.2e-05 9 38 .] 175 205 .. 167 205 .. 0.90 4 ! 25.9 0.5 6.8e-08 4e-06 2 38 .] 210 247 .. 209 247 .. 0.92 5 ? 2.5 0.0 1.7 1e+02 22 38 .] 274 290 .. 251 290 .. 0.73 6 ! 22.3 0.0 9.3e-07 5.5e-05 6 37 .. 345 377 .. 339 378 .. 0.89 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 1.2 S.SS......EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ss......vtslafspdgawlasGsdDgtvriWd 38 H ss + ++++ p+g+ l+ +++ g +W+ sp|P42841|PFS2_YEAST 86 HlSSnkvkhvIPAIQWTPEGRRLVVATYSGEFSLWN 121 443334222335677********9998899999998 PP == domain 2 score: 27.8 bits; conditional E-value: 1.7e-08 ESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriW 37 +H s vt +++s+d++w++sG+ Dg ++iW sp|P42841|PFS2_YEAST 132 QAHdSAVTTMKYSHDSDWMISGDADGMIKIW 162 58*777****************99******* PP == domain 3 score: 22.4 bits; conditional E-value: 8.8e-07 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H s++++afs++ + ++++sdD+ ++iW+ sp|P42841|PFS2_YEAST 175 AHtESIRDMAFSSNDSKFVTCSDDNILKIWN 205 79888*****999999999***********8 PP == domain 4 score: 25.9 bits; conditional E-value: 6.8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ r+l+GH +v s++++p+ ++as+s+D+ v++Wd sp|P42841|PFS2_YEAST 210 KQERVLSGHhWDVKSCDWHPEMGLIASASKDNLVKLWD 247 67899****666*************************9 PP == domain 5 score: 2.5 bits; conditional E-value: 1.7 SSEEEEE.ETTSEEEEEE CS WD40 22 gawlasG.sdDgtvriWd 38 g++l+ + s+D+++r++d sp|P42841|PFS2_YEAST 274 GNLLM-AiSKDKSCRVFD 290 55666.4499******98 PP == domain 6 score: 22.3 bits; conditional E-value: 9.3e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 + +H +++tsl+++p g+ +a++ +D+t+r+W sp|P42841|PFS2_YEAST 345 IPYAHdKCITSLSYNPVGHIFATAAKDRTIRFW 377 4559*999************************* PP >> sp|P40968|PRP17_YEAST Pre-mRNA-processing factor 17 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5592 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 7.6e-07 4.5e-05 3 38 .] 154 191 .. 152 191 .. 0.81 2 ! 27.4 0.0 2.4e-08 1.4e-06 2 38 .] 197 234 .. 196 234 .. 0.94 3 ! 28.8 0.0 8.6e-09 5.1e-07 3 37 .. 285 320 .. 283 321 .. 0.94 4 ! 17.7 0.3 2.7e-05 0.0016 3 37 .. 373 410 .. 371 411 .. 0.76 5 ? 3.8 0.0 0.68 40 8 28 .. 424 446 .. 418 455 .] 0.70 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 7.6e-07 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +r + GH + t+l+f p ++sG+ D+t++iWd sp|P40968|PRP17_YEAST 154 VIRNYPGHpEGTTALKFLPKTGHlILSGGNDHTIKIWD 191 67899***8779***96666666156***********9 PP == domain 2 score: 27.4 bits; conditional E-value: 2.4e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +clr + GH +++ +l+f d + ++s+s D++v+iWd sp|P40968|PRP17_YEAST 197 ECLRDFQGHnKPIKALRFTEDCQSFLSSSFDRSVKIWD 234 7********999*****9999999999999*******9 PP == domain 3 score: 28.8 bits; conditional E-value: 8.6e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +++t++ H ss+ +l++ pdg+ ++s+s+D+tvriW sp|P40968|PRP17_YEAST 285 LVQTYDHHlSSILALKYFPDGSKFISSSEDKTVRIW 320 5789*99***************************** PP == domain 4 score: 17.7 bits; conditional E-value: 2.7e-05 EEEEEESSSS....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGHss....vtslafspdgawlasGsdDgtvriW 37 + ++++GHss + slafs dg++++sG+ + + W sp|P40968|PRP17_YEAST 373 PKKIFKGHSSagygI-SLAFSGDGRYICSGDSKSRLFTW 410 6789****55599**.**********9877435555446 PP == domain 5 score: 3.8 bits; conditional E-value: 0.68 ESSSSEEEEEEETTSSE..EEEE CS WD40 8 tGHssvtslafspdgaw..lasG 28 G +++t ++++p + ++sG sp|P40968|PRP17_YEAST 424 PGNKPITQVDWHPQETSkvICSG 446 58999****99999888533333 PP >> sp|P32479|HIR1_YEAST Protein HIR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=HIR1 PE=1 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 0.0 3.3e-06 0.0002 12 38 .] 15 45 .. 5 45 .. 0.84 2 ! 35.0 0.1 9.3e-11 5.6e-09 4 37 .. 72 106 .. 69 106 .. 0.90 3 ! 20.1 1.0 4.6e-06 0.00028 7 38 .] 133 165 .. 127 165 .. 0.90 4 ! 15.0 0.0 0.00019 0.011 3 37 .. 171 206 .. 169 207 .. 0.89 5 ? 0.3 0.0 8.3 5e+02 18 33 .. 240 271 .. 216 278 .. 0.70 6 ? 5.0 0.2 0.28 17 10 38 .] 319 341 .. 309 341 .. 0.77 7 ! 11.3 0.1 0.0028 0.17 11 36 .. 357 382 .. 349 384 .. 0.86 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 3.3e-06 S....EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s....vtslafspdgawlasGsdDgtvriWd 38 s ++ +++s+dg+ la+G+ Dg++riW+ sp|P32479|HIR1_YEAST 15 SrkyeIYTVDVSHDGKRLATGGLDGKIRIWS 45 24556999**********************5 PP == domain 2 score: 35.0 bits; conditional E-value: 9.3e-11 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l + + H +s+t+++fspdg++lasGsdD+ + iW sp|P32479|HIR1_YEAST 72 LCSMSRHtGSITCVKFSPDGKYLASGSDDRILLIW 106 5566779888************************* PP == domain 3 score: 20.1 bits; conditional E-value: 4.6e-06 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +H +++ ++++ pd++ l++ + D++v +W+ sp|P32479|HIR1_YEAST 133 LVAHdNDIQDICWAPDSSILVTVGLDRSVIVWN 165 779*999**************9888*******8 PP == domain 4 score: 15.0 bits; conditional E-value: 0.00019 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +l+ ++ H+s v ++ f+p ++++a+ sdD+t +i+ sp|P32479|HIR1_YEAST 171 KLKRFDVHQSlVKGVVFDPANKYFATTSDDRTMKIF 206 6788999*6669**********************97 PP == domain 5 score: 0.3 bits; conditional E-value: 8.3 EETTSSEEEE................EETTSE CS WD40 18 fspdgawlas................GsdDgt 33 +spdg+ +a G++D + sp|P32479|HIR1_YEAST 240 WSPDGQHIAVpnatngpvssvaivnrGTWDTN 271 89999987644444444444555555555555 PP == domain 6 score: 5.0 bits; conditional E-value: 0.28 S..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H..ssvtslafspdgawlasGsdDgtvriWd 38 H +++ s+ +a+++ D+++ +W+ sp|P32479|HIR1_YEAST 319 HfdKNIDSV--------VATAGQDKSLAVWS 341 332338899........9************5 PP == domain 7 score: 11.3 bits; conditional E-value: 0.0028 SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvri 36 +s+t+++++pdg++l+ +s D ++ + sp|P32479|HIR1_YEAST 357 KSITDMSWNPDGSLLFVASLDSSITL 382 78*************99999*99966 PP >> sp|P18851|GBB_YEAST Guanine nucleotide-binding protein subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.1 5.8e-07 3.5e-05 3 38 .] 84 120 .. 82 120 .. 0.92 2 ? 6.4 0.0 0.1 6.1 12 36 .. 136 160 .. 127 162 .. 0.80 3 ! 17.2 0.2 4e-05 0.0024 5 38 .] 175 208 .. 171 208 .. 0.89 4 ! 14.3 0.0 0.00033 0.02 3 38 .] 214 256 .. 212 256 .. 0.82 5 ! 11.8 0.0 0.0021 0.12 6 38 .] 265 298 .. 261 298 .. 0.86 6 ? 6.5 0.1 0.092 5.5 11 38 .] 350 377 .. 336 377 .. 0.78 7 ! 28.4 0.3 1.1e-08 6.7e-07 2 38 .] 382 419 .. 381 419 .. 0.91 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 5.8e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +l+GH + ++++++s+d++ ++s+s Dg iWd sp|P18851|GBB_YEAST 84 PNIVLKGHnNKISDFRWSRDSKRILSASQDGFMLIWD 120 66789***777*************************9 PP == domain 2 score: 6.4 bits; conditional E-value: 0.1 SEEEEEEETTSSEEEEEETTSEEEE CS WD40 12 svtslafspdgawlasGsdDgtvri 36 +v s+a sp+++++as++ ++++ i sp|P18851|GBB_YEAST 136 WVLSCAISPSSTLVASAGLNNNCTI 160 58999**********9987666655 PP == domain 3 score: 17.2 bits; conditional E-value: 4e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++GH + ++++ f ++ + l++++ D t+ +Wd sp|P18851|GBB_YEAST 175 SIFKGHtCYISDIEFTDNAHILTASG-DMTCALWD 208 469***777*************9888.*******9 PP == domain 4 score: 14.3 bits; conditional E-value: 0.00033 EEEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtsla......fspdgawlasGsdDgtvriWd 38 +r+++ H ++v +la +++ +as++ Dg +iWd sp|P18851|GBB_YEAST 214 RVREYSDHlGDVLALAipeepnSENSSNTFASCGSDGYTYIWD 256 5899************9999985555555776655*******9 PP == domain 5 score: 11.8 bits; conditional E-value: 0.0021 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ s++++l+f +dg +++Gsd+g + ++d sp|P18851|GBB_YEAST 265 SFYVNdSDINALRFFKDGMSIVAGSDNGAINMYD 298 55566577********************999987 PP == domain 6 score: 6.5 bits; conditional E-value: 0.092 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v sl+fs +g+++ s+ D + +Wd sp|P18851|GBB_YEAST 350 QGVVSLDFSASGRLMYSCYTDIGCVVWD 377 3489**************8898888887 PP == domain 7 score: 28.4 bits; conditional E-value: 1.1e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + +++l+GH + vt+++ spdg +++Gs+D t +iW+ sp|P18851|GBB_YEAST 382 EIVGKLEGHgGRVTGVRSSPDGLAVCTGSWDSTMKIWS 419 67889****666*************************5 PP >> sp|P36130|CAF4_YEAST CCR4-associated factor 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.2 6.4e-05 0.0039 9 38 .] 317 348 .. 309 348 .. 0.83 2 ! 19.9 0.0 5.5e-06 0.00033 4 38 .] 355 391 .. 352 391 .. 0.88 3 ! 16.5 0.1 6.7e-05 0.004 3 38 .] 416 450 .. 414 450 .. 0.88 4 ! 11.7 0.0 0.0022 0.13 25 38 .] 502 515 .. 480 515 .. 0.85 5 ! 29.5 0.0 5e-09 3e-07 1 38 [] 519 555 .. 519 555 .. 0.86 6 ? 1.6 0.1 3.3 2e+02 24 37 .. 628 641 .. 608 642 .. 0.87 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 6.4e-05 SS.SSEEEEEEETTSSE..EEEEE.TTSEEEEEE CS WD40 9 GH.ssvtslafspdgaw..lasGs.dDgtvriWd 38 H +s+t+l + d +w l+s+s D+ v++Wd sp|P36130|CAF4_YEAST 317 EHgNSITAL--DFDTPWgtLCSSSyQDRIVKVWD 348 58889****..779999998877636*******9 PP == domain 2 score: 19.9 bits; conditional E-value: 5.5e-06 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 +++l GH v++++ ++ ++l++Gs+D t+++Wd sp|P36130|CAF4_YEAST 355 VGELPGHlATVNCMQiDKKNYNMLITGSKDATLKLWD 391 67899**999****97777777799***********9 PP == domain 3 score: 16.5 bits; conditional E-value: 6.7e-05 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 c++ ++ H++ +t+l s d+ l+sGs+D+++ Wd sp|P36130|CAF4_YEAST 416 CIHNFELHKDeITAL--SFDSEALVSGSRDKKIFHWD 450 899999**556****..77888899***********9 PP == domain 4 score: 11.7 bits; conditional E-value: 0.0022 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 la+G++Dg vr+Wd sp|P36130|CAF4_YEAST 502 LATGTKDGIVRLWD 515 79***********9 PP == domain 5 score: 29.5 bits; conditional E-value: 5e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g+++r l+GH +++tsl+f d+ l++Gs+D++vriWd sp|P36130|CAF4_YEAST 519 GKPVRLLEGHtDGITSLKF--DSEKLVTGSMDNSVRIWD 555 689999****777****55..555588***********9 PP == domain 6 score: 1.6 bits; conditional E-value: 3.3 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 +l+ G+ Dg + +W sp|P36130|CAF4_YEAST 628 FLINGHNDGDINVW 641 4778999******* PP >> sp|P33750|DCA13_YEAST Protein SOF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SOF1 PE=1 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.0 0.00078 0.047 9 38 .] 65 96 .. 58 96 .. 0.80 2 ! 19.0 0.0 1.1e-05 0.00064 6 38 .] 105 149 .. 100 149 .. 0.80 3 ? 0.6 0.0 6.8 4.1e+02 4 38 .] 173 205 .. 170 205 .. 0.75 4 ? 9.0 0.1 0.015 0.9 9 38 .] 218 248 .. 209 248 .. 0.68 5 ! 26.3 0.0 5.4e-08 3.2e-06 4 37 .. 298 332 .. 295 333 .. 0.92 6 ! 22.8 0.1 6.6e-07 3.9e-05 10 37 .. 350 375 .. 334 376 .. 0.80 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.00078 SS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtsla.fspdgawlasGsdDgtvriWd 38 GH ++v+++a + + + la+Gs Dg ++ W+ sp|P33750|DCA13_YEAST 65 GHrDGVYAIAkNYGSLNKLATGSADGVIKYWN 96 9988899996655555559************8 PP == domain 2 score: 19.0 bits; conditional E-value: 1.1e-05 EEESS.SSEEEEE...........EETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtsla...........fspdgawlasGsdDgtvriWd 38 ++++H + vt+l+ +++++++s+sdD+tv++W+ sp|P33750|DCA13_YEAST 105 SFKAHyGLVTGLCvtqprfhdkkpDLKSQNFMLSCSDDKTVKLWS 149 688885558888888888888777777779999***********5 PP == domain 3 score: 0.6 bits; conditional E-value: 6.8 EEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGHssvtslafspdgawlasGsdDgtvriWd 38 +rt++G s +++ +++++ +a+G ++++Wd sp|P33750|DCA13_YEAST 173 IRTFDGESAFQGIDSHRENSTFATG--GAKIHLWD 205 6777777667889999999999886..66777776 PP == domain 4 score: 9.0 bits; conditional E-value: 0.015 SSSSEEEEEEETTSSE.EE.EEETTSEEEEEE CS WD40 9 GHssvtslafspdgaw.la.sGsdDgtvriWd 38 G +++tsl+f+++ + la +Gs D+++ ++d sp|P33750|DCA13_YEAST 218 GADNITSLKFNQNETDiLAsTGS-DNSIVLYD 248 44459999966666662554678.*****998 PP == domain 5 score: 26.3 bits; conditional E-value: 5.4e-08 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 l +++ H s v +++fsp g+ +++Gs+D+++ri+ sp|P33750|DCA13_YEAST 298 LNVFKDHvSAVMDVDFSPTGDEIVTGSYDKSIRIY 332 67899**999************************8 PP == domain 6 score: 22.8 bits; conditional E-value: 6.6e-07 SSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 10 HssvtslafspdgawlasGsdDgtvriW 37 H v +++s d+++++sGsdDg+vr+W sp|P33750|DCA13_YEAST 350 H--VFQVKYSMDSKYIISGSDDGNVRLW 375 3..88999******************** PP >> sp|Q12024|YTM1_YEAST Ribosome biogenesis protein YTM1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 1.6 0.0014 0.086 11 38 .] 104 131 .. 95 131 .. 0.84 2 ! 23.8 0.0 3.2e-07 1.9e-05 2 38 .] 135 171 .. 134 171 .. 0.87 3 ! 19.6 0.1 6.6e-06 0.0004 1 38 [] 198 235 .. 198 235 .. 0.88 4 ? 8.7 0.0 0.018 1.1 3 38 .] 279 316 .. 277 316 .. 0.83 5 ! 31.8 0.1 9.3e-10 5.6e-08 4 38 .] 368 404 .. 365 404 .. 0.88 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.0014 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v+sl++ + ++ ++sGs+Dg vr Wd sp|Q12024|YTM1_YEAST 104 DWVSSLDVGDGSKHIISGSYDGIVRTWD 131 55999*99999999*************9 PP == domain 2 score: 23.8 bits; conditional E-value: 3.2e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + ++ ++GH ++++++++ ++ +++++G D+t+r+W+ sp|Q12024|YTM1_YEAST 135 NVQKQYSGHsGPIRAVKYISNTRLVSAGN-DRTLRLWK 171 67899****777****9999999997777.*******6 PP == domain 3 score: 19.6 bits; conditional E-value: 6.6e-06 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 g++l +l+GH +v s+++s++++ l+ +s+D+++ +W+ sp|Q12024|YTM1_YEAST 198 GKTLAILEGHkAPVVSIDVSDNSRILS-ASYDNSIGFWS 235 678999****77799**********95.677****9995 PP == domain 4 score: 8.7 bits; conditional E-value: 0.018 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 +l l+ H +v + f++ + + s s D+t++ Wd sp|Q12024|YTM1_YEAST 279 PLSLLESHtAPVEQVIFDSTDNTVgYSVSQDHTIKTWD 316 56668899888************8545589*******9 PP == domain 5 score: 31.8 bits; conditional E-value: 9.3e-10 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ l GH ++v+sl+++p++ +++ sGs Dgtv++Wd sp|Q12024|YTM1_YEAST 368 QQQLIGHkNFVSSLDTCPENEYILcSGSHDGTVKVWD 404 67789**999************7638899*******9 PP >> sp|Q04660|ERB1_YEAST Ribosome biogenesis protein ERB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.5 0.2 1.5e-11 9.3e-10 2 37 .. 428 464 .. 427 465 .. 0.92 2 ? 0.2 0.0 9 5.4e+02 10 23 .. 487 498 .. 481 508 .. 0.81 3 ? 6.6 0.0 0.087 5.2 12 38 .] 636 666 .. 620 666 .. 0.77 4 ? 0.7 0.0 6.6 4e+02 15 34 .. 685 704 .. 675 707 .. 0.82 5 ! 12.9 0.0 0.00087 0.052 4 37 .. 716 750 .. 713 751 .. 0.89 6 ! 22.0 0.1 1.2e-06 7.1e-05 3 37 .. 766 805 .. 764 806 .. 0.84 Alignments for each domain: == domain 1 score: 37.5 bits; conditional E-value: 1.5e-11 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 +c +++ GH++ v+ l+ +p+g wla+GsdDgtvr+W sp|Q04660|ERB1_YEAST 428 RCSTIYAGHKGkVRTLSIDPSGLWLATGSDDGTVRVW 464 68999****555************************* PP == domain 2 score: 0.2 bits; conditional E-value: 9 SSSEEEEEEETTSS CS WD40 10 Hssvtslafspdga 23 H + ++ ++pd + sp|Q04660|ERB1_YEAST 487 H--IECIEWNPDAN 498 4..99******987 PP == domain 3 score: 6.6 bits; conditional E-value: 0.087 S.....EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s.....vtslafspdgawlasGsdDgtvriWd 38 + + +f+p ++ l+ +s + vri+d sp|Q04660|ERB1_YEAST 636 KkskgiIMDAKFHPFKPQLFVCS-QRYVRIYD 666 04455578999************.*******8 PP == domain 4 score: 0.7 bits; conditional E-value: 6.6 EEEEETTSSEEEEEETTSEE CS WD40 15 slafspdgawlasGsdDgtv 34 ++ +p g+ l+++s D+ v sp|Q04660|ERB1_YEAST 685 KIDIHPRGDNLIASSFDKRV 704 56789999999988889887 PP == domain 5 score: 12.9 bits; conditional E-value: 0.00087 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +tl+ H + v+s+ f++ ++++s+ dDgt++++ sp|Q04660|ERB1_YEAST 716 YKTLRYHeKAVRSVNFHKKLPLFSSAADDGTIHVF 750 578889*999*************99999****996 PP == domain 6 score: 22.0 bits; conditional E-value: 1.2e-06 EEEEEESSSSEEEEE.....EETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGHssvtsla.....fspdgawlasGsdDgtvriW 37 +l++ltGH+ ++sl ++p awl+s++ D+t r+W sp|Q04660|ERB1_YEAST 766 PLKKLTGHKVINSLGvldaiWHPREAWLFSAGADNTARLW 805 7899****556766666777********99999******* PP >> sp|P38123|SWD3_YEAST COMPASS component SWD3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SW # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.52 31 14 26 .. 17 29 .. 3 37 .. 0.80 2 ! 15.9 0.1 9.8e-05 0.0059 8 36 .. 52 81 .. 44 82 .. 0.80 3 ! 29.0 0.0 7.6e-09 4.5e-07 3 38 .] 88 124 .. 86 124 .. 0.94 4 ! 18.1 0.0 2e-05 0.0012 2 38 .] 129 167 .. 128 167 .. 0.81 5 ! 12.5 0.1 0.0012 0.074 12 38 .] 188 217 .. 171 217 .. 0.69 6 ? 3.6 0.0 0.76 45 21 38 .] 252 269 .. 226 269 .. 0.85 7 ? 1.5 0.4 3.6 2.2e+02 7 37 .. 283 312 .. 279 313 .. 0.62 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.52 EEEEEETTSSEEE CS WD40 14 tslafspdgawla 26 t+ + spdg++la sp|P38123|SWD3_YEAST 17 TCAKISPDGQFLA 29 8999*******97 PP == domain 2 score: 15.9 bits; conditional E-value: 9.8e-05 ESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvri 36 t H + + l++spdg+ +a++sdD +v i sp|P38123|SWD3_YEAST 52 TSHaRPFSELCWSPDGQCIATASDDFSVEI 81 45644467899**************99987 PP == domain 3 score: 29.0 bits; conditional E-value: 7.6e-09 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +l+t+ GH +v sl f++ g++l+++s+D +++iWd sp|P38123|SWD3_YEAST 88 LLHTFIGHtAPVISLTFNRKGNLLFTSSMDESIKIWD 124 69******88888***********************9 PP == domain 4 score: 18.1 bits; conditional E-value: 2e-05 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 ++++t+++H v s++ d++ l+sGs+Dg +ri+d sp|P38123|SWD3_YEAST 129 SLMKTISAHsEAVVSVDvPMNDSSILSSGSYDGLIRIFD 167 67899****55599**9666666667899********98 PP == domain 5 score: 12.5 bits; conditional E-value: 0.0012 S...EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 12 s...vtslafspdgawla.sGsdDgtvriWd 38 + ++ ++fs + ++l+ + Dg v+iWd sp|P38123|SWD3_YEAST 188 GvvpISQVKFSENARYLLvKSL-DGVVKIWD 217 1555899*********862655.*******9 PP == domain 6 score: 3.6 bits; conditional E-value: 0.76 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 + ++++sG ++g ++ W+ sp|P38123|SWD3_YEAST 252 STPLVISGYENGDIYCWN 269 446699***********8 PP == domain 7 score: 1.5 bits; conditional E-value: 3.6 EESS.SS...EEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasG.sdDgtvriW 37 l H s+ ++++ g+ + ++ +g + +W sp|P38123|SWD3_YEAST 283 LYHHsSPvmsIHCF-----GNIM-CSlALNGDCCLW 312 56685555556666.....5554.444458888888 PP >> sp|P40217|EIF3I_YEAST Eukaryotic translation initiation factor 3 subunit I OS=Saccharomyces cerevisiae (strain ATCC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 4.1e-05 0.0024 6 37 .. 5 37 .. 2 37 .. 0.94 2 ! 24.8 1.0 1.6e-07 9.5e-06 2 38 .] 43 80 .. 42 80 .. 0.92 3 ? 3.7 0.0 0.7 42 1 26 [. 84 109 .. 84 118 .. 0.85 4 ! 10.3 0.0 0.0059 0.36 3 35 .. 143 178 .. 141 181 .. 0.73 5 ! 10.6 0.0 0.0047 0.28 10 32 .. 195 218 .. 187 222 .. 0.90 6 ! 14.0 0.0 0.0004 0.024 5 36 .. 287 319 .. 283 321 .. 0.88 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 4.1e-05 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 +ltGH + t ++++++g++l+s+s+D + +W sp|P40217|EIF3I_YEAST 5 KLTGHeRPLTQVKYNKEGDLLFSCSKDSSASVW 37 589**888************************9 PP == domain 2 score: 24.8 bits; conditional E-value: 1.6e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + l+tl+GH + ++s++++ ++ ++Gs D ++++Wd sp|P40217|EIF3I_YEAST 43 ERLGTLDGHtGTIWSIDVDCFTKYCVTGSADYSIKLWD 80 6789*****777*************************9 PP == domain 3 score: 3.7 bits; conditional E-value: 0.7 TEEEEEEESSSSEEEEEEETTSSEEE CS WD40 1 gqclrtltGHssvtslafspdgawla 26 gqc+ t++ +v + fsp g++++ sp|P40217|EIF3I_YEAST 84 GQCVATWKSPVPVKRVEFSPCGNYFL 109 6888888876779**********976 PP == domain 4 score: 10.3 bits; conditional E-value: 0.0059 EEEEEESSSSEEEEE......EETTSSEEEEEETTSEEE CS WD40 3 clrtltGHssvtsla......fspdgawlasGsdDgtvr 35 +++++ +H + + +s g+++++G++Dg++ sp|P40217|EIF3I_YEAST 143 PIHKIITHEGL---DaatvagWSTKGKYIIAGHKDGKIS 178 66777777333...3334559***************996 PP == domain 5 score: 10.6 bits; conditional E-value: 0.0047 S.SSEEEEEEETTSSEEEEEETTS CS WD40 10 H.ssvtslafspdgawlasGsdDg 32 H +s+++++fspd ++++++s+D sp|P40217|EIF3I_YEAST 195 HeKSISDMQFSPDLTYFITSSRDT 218 9999*****************996 PP == domain 6 score: 14.0 bits; conditional E-value: 0.0004 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvri 36 + GH ++ + +a sp g+ asG++Dg +r+ sp|P40217|EIF3I_YEAST 287 GRVQGHfGPLNTVAISPQGTSYASGGEDGFIRL 319 5568**888**********************97 PP >> sp|P39946|LIS1_YEAST Nuclear distribution protein PAC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 3.3 2e+02 11 31 .. 156 175 .. 148 180 .. 0.81 2 ? 6.5 0.0 0.091 5.5 3 37 .. 190 234 .. 189 235 .. 0.81 3 ! 25.9 0.4 7.1e-08 4.3e-06 2 38 .] 244 283 .. 243 283 .. 0.88 4 ! 12.6 0.8 0.0011 0.068 2 36 .. 288 321 .. 287 324 .. 0.86 5 ! 15.6 0.0 0.00012 0.0073 4 37 .. 330 385 .. 327 386 .. 0.86 6 ! 25.7 0.6 8e-08 4.8e-06 2 38 .] 408 443 .. 407 443 .. 0.95 7 ? 5.8 0.1 0.16 9.6 1 32 [. 447 487 .. 447 492 .. 0.75 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 3.3 SSEEEEEEETTSSEEEEEETT CS WD40 11 ssvtslafspdgawlasGsdD 31 ssvts++ +p+ + ++ ++ D sp|P39946|LIS1_YEAST 156 SSVTSVKLHPNLPIVFVAT-D 175 46*********99988777.5 PP == domain 2 score: 6.5 bits; conditional E-value: 0.091 EEEEEESS.SSEEEEE.......EETTSSE..EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtsla.......fspdgaw..lasGsdDgtvriW 37 +l +l H + +ts++ +s+ +++ ++++s+D ++++ sp|P39946|LIS1_YEAST 190 PLASLQSHtKAITSMDvlftnytNSSKKNYlvIVTASKDLQIHVF 234 5789999*999*****99999998888888433599999888886 PP == domain 3 score: 25.9 bits; conditional E-value: 7.1e-08 EEEEEEESSSS.EEEEE.EETTSSE.EEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtsla.fspdgaw.lasGsdDgtvriWd 38 q++r+l GH + v++++ ++++++ +as+s+D+tv+iWd sp|P39946|LIS1_YEAST 244 QQIRSLLGHEHiVSAVKiWQKNNDVhIASCSRDQTVKIWD 283 78999****77579999********55799*********9 PP == domain 4 score: 12.6 bits; conditional E-value: 0.0011 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 + l+t+ H ++v+s+ + g++++sGs D t+r+ sp|P39946|LIS1_YEAST 288 WSLKTFQPHsQWVRSI--DVLGDYIISGSHDTTLRL 321 57899999*777**99..77899999**99****98 PP == domain 5 score: 15.6 bits; conditional E-value: 0.00012 EEEEESS.SSEEEEE.................EETTSSE....EEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla.................fspdgaw....lasGsdDgtvriW 37 l + tGH +++ ++ ++++++w +s+s+D+t++iW sp|P39946|LIS1_YEAST 330 LSVGTGHeFPIEKVKfihfiedspeirfrtpsTDRYKNWgmqyCVSASRDRTIKIW 385 667789988899888888999999999999999999999*999778999******* PP == domain 6 score: 25.7 bits; conditional E-value: 8e-08 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +c+ tl+GH s+v+++ s g++l+s+ dD++vr Wd sp|P39946|LIS1_YEAST 408 RCVLTLKGHlSWVRDI--SIRGQYLFSCADDKSVRCWD 443 79************99..9999***************9 PP == domain 7 score: 5.8 bits; conditional E-value: 0.16 TEEEEEEE.SS.SSEEEEE..EETTSSE.....EEEEETTS CS WD40 1 gqclrtlt.GH.ssvtsla..fspdgaw.....lasGsdDg 32 gqcl++++ H ++v++l+ ++ d++ +++G+ D+ sp|P39946|LIS1_YEAST 447 GQCLHVWEkLHtGFVNCLDldVDFDSNVtprqmMVTGGLDC 487 68999985588677****97777777667777767888776 PP >> sp|P20484|MAK11_YEAST Protein MAK11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MAK11 PE=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 0.0001 0.0062 3 38 .] 44 78 .. 42 78 .. 0.86 2 ! 21.4 0.6 1.9e-06 0.00011 2 37 .. 83 134 .. 82 135 .. 0.93 3 ! 29.1 0.6 6.7e-09 4e-07 1 38 [] 139 177 .. 139 177 .. 0.92 4 ? 2.4 0.0 1.8 1.1e+02 13 37 .. 241 266 .. 234 266 .. 0.85 5 ! 13.9 0.0 0.00044 0.026 6 38 .] 295 330 .. 291 330 .. 0.85 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.0001 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ ++ +H s+ +l + ++l+sGs D ++ri+d sp|P20484|MAK11_YEAST 44 PIFHFQAHsLSIKCL--AVSRRYLVSGSNDEHIRIYD 78 67899***655*999..55788899***********8 PP == domain 2 score: 21.4 bits; conditional E-value: 1.9e-06 EEEEEEESS.SSEEEEE...............EETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtsla...............fspdgawlasGsdDgtvriW 37 + l+tl H +s+t+l+ s++++wl+s+s+D+++++W sp|P20484|MAK11_YEAST 83 KELGTLLSHqGSITALQfshpasssedaavskGSKNSKWLLSASEDHKIMVW 134 67889999*888**************************************** PP == domain 3 score: 29.1 bits; conditional E-value: 6.7e-09 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++++tl+GH v++++ +p ++ +s sdD+++r+W+ sp|P20484|MAK11_YEAST 139 WETVGTLKGHtARVNDVDIHPTNRIAISVSDDHSIRLWN 177 57899*****666************9999*********8 PP == domain 4 score: 2.4 bits; conditional E-value: 1.8 E.EEEEEETTSSEEEEE.ETTSEEEEE CS WD40 13 v.tslafspdgawlasG.sdDgtvriW 37 + t++ +++ +l+ G s Dg+v+++ sp|P20484|MAK11_YEAST 241 IeTHILPFDNKEYLSVGiS-DGNVHFY 266 667888899999**99***.****975 PP == domain 5 score: 13.9 bits; conditional E-value: 0.00044 EEESS.SSEEEEE..EETTSSEEE.EEETTSEEEEEE CS WD40 6 tltGH.ssvtsla..fspdgawla.sGsdDgtvriWd 38 +l GH + + +++ ++ g++l+ Gs Dg++ +Wd sp|P20484|MAK11_YEAST 295 SLLGHtNRIKDFKfyTNEFGTYLVtIGS-DGKIVVWD 330 6779*888*999999999999987359*.*******9 PP >> sp|Q04491|SEC13_YEAST Protein transport protein SEC13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.0 0.0 0.0017 0.1 9 37 .. 7 36 .. 3 37 .. 0.84 2 ! 24.5 0.6 1.9e-07 1.2e-05 3 38 .] 45 83 .. 43 83 .. 0.82 3 ? 8.6 0.1 0.021 1.3 9 36 .. 97 127 .. 89 128 .. 0.67 4 ? 9.3 0.0 0.013 0.76 24 38 .] 168 186 .. 137 186 .. 0.65 5 ! 19.2 0.3 9.1e-06 0.00054 5 37 .. 198 234 .. 194 235 .. 0.88 6 ? 8.0 0.1 0.031 1.8 14 38 .] 258 282 .. 248 282 .. 0.84 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.0017 SSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriW 37 +H+ +++ + +g+ la++s D+t++i+ sp|Q04491|SEC13_YEAST 7 AHNElIHDAVLDYYGKRLATCSSDKTIKIF 36 57556788888899*******88*****97 PP == domain 2 score: 24.5 bits; conditional E-value: 1.9e-07 EEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 ++ tltGH ++v+ ++ ++ g+ las+s+Dg+v iW+ sp|Q04491|SEC13_YEAST 45 LIDTLTGHeGPVWRVDwaHPKFGTILASCSYDGKVLIWK 83 6789****999****5555555555*************6 PP == domain 3 score: 8.6 bits; conditional E-value: 0.021 SS.SSEEEEE..EETTSSE.EEEEETTSEEEE CS WD40 9 GH.ssvtsla..fspdgaw.lasGsdDgtvri 36 H sv+s++ + +g++ l+++s Dg+v + sp|Q04491|SEC13_YEAST 97 VHsASVNSVQwaPHEYGPLlLVASS-DGKVSV 127 58666****6555666666445667.**9975 PP == domain 4 score: 9.3 bits; conditional E-value: 0.013 E....EEEEETTSEEEEEE CS WD40 24 w....lasGsdDgtvriWd 38 +++G+ D+ v+iW+ sp|Q04491|SEC13_YEAST 168 KesrkFVTGGADNLVKIWK 186 14444789*99*******6 PP == domain 5 score: 19.2 bits; conditional E-value: 9.1e-06 EEEESS.SSEEEEEEETTSSE...EEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw...lasGsdDgtvriW 37 tl+GH ++v+++a+sp + las s D+t+ iW sp|Q04491|SEC13_YEAST 198 STLEGHsDWVRDVAWSPTVLLrsyLASVSQDRTCIIW 234 689***666****999998889999999********* PP == domain 6 score: 8.0 bits; conditional E-value: 0.031 EEEEEETTSSEEE.EEETTSEEEEEE CS WD40 14 tslafspdgawla.sGsdDgtvriWd 38 + ++s +g+ la sG+ D++v +W+ sp|Q04491|SEC13_YEAST 258 WRASWSLSGNVLAlSGG-DNKVTLWK 282 56678889999977***.*******6 PP >> sp|Q04199|CAC2_YEAST Chromatin assembly factor 1 subunit p60 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.1 8.4e-05 0.005 10 38 .] 11 43 .. 4 43 .. 0.71 2 ! 20.0 0.0 5.2e-06 0.00031 4 38 .] 64 99 .. 61 99 .. 0.92 3 ! 18.3 0.0 1.7e-05 0.001 12 38 .] 145 173 .. 133 173 .. 0.78 4 ! 10.7 0.2 0.0046 0.27 8 37 .. 186 214 .. 179 214 .. 0.84 5 ! 12.8 0.2 0.00097 0.058 10 33 .. 372 396 .. 364 398 .. 0.86 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 8.4e-05 S..SSEEEEE...EETTSSEEEEEETTSEEEEEE CS WD40 10 H..ssvtsla...fspdgawlasGsdDgtvriWd 38 H ++v+sl +s + +++++G+ D++vriW+ sp|Q04199|CAC2_YEAST 11 HdsQPVYSLTfqkNSANDKLFTAGG-DNKVRIWK 43 8534488888444666666688999.*******6 PP == domain 2 score: 20.0 bits; conditional E-value: 5.2e-06 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l++lt H + ++ ++f++ g+ las++dDg v +W+ sp|Q04199|CAC2_YEAST 64 LGSLTHHeQAINVIRFNSKGDVLASAGDDGQVLLWK 99 7899999888*************************6 PP == domain 3 score: 18.3 bits; conditional E-value: 1.7e-05 S..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s..vtslafspdgawlasGsdDgtvriWd 38 +++la+spd++ ++ +++D+++r++d sp|Q04199|CAC2_YEAST 145 AaeIYDLAWSPDNRNIVVACMDNSIRLFD 173 1569***********987777******98 PP == domain 4 score: 10.7 bits; conditional E-value: 0.0046 ESSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHssvtslafspdgawlasGsdDgtvriW 37 GH v ++a++p +++++s s D++++++ sp|Q04199|CAC2_YEAST 186 HGH-YVQGVAWDPLNQFILSQSADRSLHVY 214 477.8**************7688***9986 PP == domain 5 score: 12.8 bits; conditional E-value: 0.00097 S.SSEEEEEEETTSSEEEEEETTSE CS WD40 10 H.ssvtslafspdgawlasGsdDgt 33 H s++t+la+s dg+ l+ +s Dg sp|Q04199|CAC2_YEAST 372 HySPITDLAWSEDGSTLLISSTDGF 396 8899************987777996 PP >> sp|P53011|SEH1_YEAST Nucleoporin SEH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SEH1 PE= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.3 1.3e-05 0.00078 8 37 .. 6 36 .. 1 37 [. 0.88 2 ! 19.6 0.3 7e-06 0.00042 4 37 .. 48 84 .. 45 85 .. 0.78 3 ? 2.5 0.0 1.8 1.1e+02 24 38 .] 122 138 .. 98 138 .. 0.61 4 ! 15.8 0.1 0.00011 0.0067 6 37 .. 207 243 .. 201 244 .. 0.82 5 ! 23.5 0.4 3.9e-07 2.4e-05 7 38 .] 300 332 .. 291 332 .. 0.81 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 1.3e-05 ESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 8 tGHss.vtslafspdgawlasGsdDgtvriW 37 +GH++ v+++ ++ +g+ +a++s D++++++ sp|P53011|SEH1_YEAST 6 SGHDDlVHDVVYDFYGRHVATCSSDQHIKVF 36 5**6689***************88*****97 PP == domain 2 score: 19.6 bits; conditional E-value: 7e-06 EEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEE CS WD40 4 lrtltGH.ssvtsla..fspdgawlasGsdDgtvriW 37 ++++H ss+ +++ + +g+ +as+s+D+tv++W sp|P53011|SEH1_YEAST 48 SDSWRAHdSSIVAIDwaSPEYGRIIASASYDKTVKLW 84 56789**888999966566666669999********* PP == domain 3 score: 2.5 bits; conditional E-value: 1.8 EE.EEE.ETTSEEEEEE CS WD40 24 wl.asG.sdDgtvriWd 38 l +++ + Dg +r++d sp|P53011|SEH1_YEAST 122 GLkLAClGNDGILRLYD 138 323456677******98 PP == domain 4 score: 15.8 bits; conditional E-value: 0.00011 EEESSSS.EEEEEEETTSSE..........EEEEETTSEEEEE CS WD40 6 tltGHss.vtslafspdgaw..........lasGsdDgtvriW 37 +l GH+s ++s+ +w +a+G++Dg +ri+ sp|P53011|SEH1_YEAST 207 KLPGHKSlIRSI------SWapsigrwyqlIATGCKDGRIRIF 243 588**8879***......66666666799899**********8 PP == domain 5 score: 23.5 bits; conditional E-value: 3.9e-07 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 + H++ v+s++++ g+ l+s++dDg+vr+W+ sp|P53011|SEH1_YEAST 300 HDDHNGeVWSVSWNLTGTILSSAGDDGKVRLWK 332 3446447**************999********6 PP >> sp|P38262|SIF2_YEAST SIR4-interacting protein SIF2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.1 6.2e-07 3.7e-05 11 38 .] 221 248 .. 206 248 .. 0.86 2 ? 7.0 0.1 0.065 3.9 3 27 .. 253 278 .. 251 294 .. 0.83 3 ! 25.2 0.1 1.2e-07 7.2e-06 3 37 .. 351 386 .. 349 387 .. 0.91 4 ! 19.9 1.7 5.7e-06 0.00034 2 38 .] 392 428 .. 391 428 .. 0.84 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 6.2e-07 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 + vt+la+s+dg+ +++G ++g +r+W+ sp|P38262|SIF2_YEAST 221 NQVTCLAWSHDGNSIVTGVENGELRLWN 248 45****************99*******8 PP == domain 2 score: 7.0 bits; conditional E-value: 0.065 EEEEEESS.SSEEEEEEETTSSEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlas 27 +l +l H ++ s+++++dg+ ++s sp|P38262|SIF2_YEAST 253 LLNVLNFHrAPIVSVKWNKDGTHIIS 278 6778899*99999**********984 PP == domain 3 score: 25.2 bits; conditional E-value: 1.2e-07 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++++l GH ++++ l f++ +++l+s+sdDgt+riW sp|P38262|SIF2_YEAST 351 PTGKLIGHhGPISVLEFNDTNKLLLSASDDGTLRIW 386 678899**999*9999******************** PP == domain 4 score: 19.9 bits; conditional E-value: 5.7e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 + + + GH +s+ s ++ d + + s+s+Dg+vr+W+ sp|P38262|SIF2_YEAST 392 NSQNCFYGHsQSIVSASWVGDDKVI-SCSMDGSVRLWS 428 5677899**88899**888888887.7899*******5 PP >> sp|P40066|GLE2_YEAST Nucleoporin GLE2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GLE2 PE= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 0.3 1e-07 6.1e-06 12 38 .] 38 65 .. 30 65 .. 0.86 2 ! 15.8 0.0 0.00011 0.0067 10 38 .] 77 108 .. 71 108 .. 0.87 3 ! 13.9 0.0 0.00044 0.026 19 38 .] 134 153 .. 115 153 .. 0.81 4 ! 13.8 0.0 0.00048 0.029 12 38 .] 267 297 .. 247 297 .. 0.76 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 1e-07 SEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 12 svtslafspdgawlasG.sdDgtvriWd 38 s++++afsp +++++s+ s+Dg+vriWd sp|P40066|GLE2_YEAST 38 SISDIAFSPQQDFMFSAsSWDGKVRIWD 65 599**********986648********9 PP == domain 2 score: 15.8 bits; conditional E-value: 0.00011 S.SS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ss..vtslafspdgawlasGsdDgtvriWd 38 H ss v + ++s dg+ +asG+ D+ ++++d sp|P40066|GLE2_YEAST 77 HeSSspVLCTRWSNDGTKVASGGCDNALKLYD 108 6633469***************88******98 PP == domain 3 score: 13.9 bits; conditional E-value: 0.00044 ETTSSEEEEEETTSEEEEEE CS WD40 19 spdgawlasGsdDgtvriWd 38 +++ +++Gs+D+t++ Wd sp|P40066|GLE2_YEAST 134 PSNTECIVTGSWDKTIKYWD 153 55556689***********9 PP == domain 4 score: 13.8 bits; conditional E-value: 0.00048 S....EEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 12 s....vtslafspdgawla.sGsdDgtvriWd 38 s v+s+af+p ++ +G+ Dgt +Wd sp|P40066|GLE2_YEAST 267 SlvypVNSIAFHPLYGTFVtAGG-DGTFNFWD 297 1445599**98888888762567.*******9 PP >> sp|P46680|AIP1_YEAST Actin-interacting protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.2 0.1 0.0015 0.088 5 37 .. 57 93 .. 54 93 .. 0.80 2 ? 5.4 0.0 0.21 13 2 37 .. 151 188 .. 150 189 .. 0.66 3 ? 8.8 0.1 0.018 1.1 9 38 .] 202 235 .. 194 235 .. 0.74 4 ! 11.8 0.1 0.0021 0.12 12 38 .] 255 280 .. 248 280 .. 0.87 5 ! 14.0 0.0 0.00041 0.025 3 37 .. 331 362 .. 329 363 .. 0.87 6 ? 1.1 0.1 4.9 2.9e+02 9 36 .. 370 397 .. 365 397 .. 0.79 7 ? 3.8 0.0 0.68 41 10 37 .. 530 568 .. 521 569 .. 0.71 8 ? 9.1 0.0 0.014 0.85 4 38 .] 577 611 .. 574 611 .. 0.84 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.0015 EEEESS.SS.EEEEEEETTSSE..EEEEETTSEEEEE CS WD40 5 rtltGH.ss.vtslafspdgaw..lasGsdDgtvriW 37 +tGH ss vt ++fsp + l+sG++ g+v +W sp|P46680|AIP1_YEAST 57 VQFTGHgSSvVTTVKFSPIKGSqyLCSGDESGKVIVW 93 5699**87767***9666655566999999*****99 PP == domain 2 score: 5.4 bits; conditional E-value: 0.21 EEEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgaw..lasGsdDgtvriW 37 + l++ +GH + ++++ ++ ++ ++ G+ Dg+v ++ sp|P46680|AIP1_YEAST 151 NSLGEVSGHsQRINACHLKQSRPMrsMTVGD-DGSVVFY 188 678999***666*988533333335455566.9999876 PP == domain 3 score: 8.8 bits; conditional E-value: 0.018 SS.SS..EEEEEEETTSSEEE..EEETTSEEEEEE CS WD40 9 GH.ss..vtslafspdgawla..sGsdDgtvriWd 38 H ++ v+++ fspd+ ++ Gs D+++ +d sp|P46680|AIP1_YEAST 202 HHkQGsfVRDVEFSPDSGEFVitVGS-DRKISCFD 235 3452256*********9996433689.**998766 PP == domain 4 score: 11.8 bits; conditional E-value: 0.0021 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++ +l++ +++++ + G D t+r+Wd sp|P46680|AIP1_YEAST 255 GIFALSWLDSQKFATVGA-DATIRVWD 280 4889999999***87778.*******9 PP == domain 5 score: 14.0 bits; conditional E-value: 0.00041 EEEEEESS.SSEEEEEEETTSSE..EEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw..lasGsdDgtvriW 37 l+t++GH +++t+l + l+sGs+Dg ++ W sp|P46680|AIP1_YEAST 331 VLKTISGHnKGITAL------TVnpLISGSYDGRIMEW 362 58999***999****......7788889*******988 PP == domain 6 score: 1.1 bits; conditional E-value: 4.9 SSSS.EEEEEEETTSSEEEEE.ETTSEEEE CS WD40 9 GHss.vtslafspdgawlasG.sdDgtvri 36 Hs+ + sl++s+ + + s+ s+D t+++ sp|P46680|AIP1_YEAST 370 DHSNlIVSLDNSKAQEY--SSiSWDDTLKV 397 46446889999999999..6779****997 PP == domain 7 score: 3.8 bits; conditional E-value: 0.68 S.SSEEEEEEETTSSE................EEEEETTSEEEEE CS WD40 10 H.ssvtslafspdgaw................lasGsdDgtvriW 37 H s ++++ +w +a+Gs D ++ i+ sp|P46680|AIP1_YEAST 530 HtSKINAI------SWkpaekganeeeieedlVATGSLDTNIFIY 568 64447777......55555555667777777699********998 PP == domain 8 score: 9.1 bits; conditional E-value: 0.014 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ l +H ++v+ l + +++++sG D ++ W+ sp|P46680|AIP1_YEAST 577 IKALNAHkDGVNNLLWETPSTLVSSGA-DACIKRWN 611 667899*666****9999999998888.*****997 PP >> sp|P53197|CDH1_YEAST APC/C activator protein CDH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.7 1.6e-05 0.00093 1 34 [. 334 366 .. 334 368 .. 0.85 2 ! 11.1 0.0 0.0032 0.19 7 37 .. 381 412 .. 377 413 .. 0.87 3 ! 18.1 0.0 2e-05 0.0012 3 38 .] 419 458 .. 417 458 .. 0.82 4 ? 1.1 0.2 4.8 2.9e+02 12 38 .] 473 501 .. 464 501 .. 0.78 5 ! 19.3 0.0 8.4e-06 0.0005 2 38 .] 506 543 .. 505 543 .. 0.88 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 1.6e-05 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 1 gqclrtltGH.ssvtslafspdgawlasGsdDgtv 34 ++c+rtl+GH + v +l s +++ l+sGs+D+ + sp|P53197|CDH1_YEAST 334 RKCIRTLSGHiDRVACL--SWNNHVLTSGSRDHRI 366 58********999****..44666699*****988 PP == domain 2 score: 11.1 bits; conditional E-value: 0.0032 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++ H + v++l+++ + lasG+ D+ v+++ sp|P53197|CDH1_YEAST 381 IESHtQEVCGLKWNVADNKLASGGNDNVVHVY 412 5789777****99999999**********998 PP == domain 3 score: 18.1 bits; conditional E-value: 2e-05 EEEEEESS.SSEEEEEEETTSSEE.EEEE..TTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGs..dDgtvriWd 38 ++ t++ H v ++a+sp+++ + a+G+ D+ ++iW+ sp|P53197|CDH1_YEAST 419 PILTFDEHkAAVKAMAWSPHKRGVlATGGgtADRRLKIWN 458 78899***666************625774347*******8 PP == domain 4 score: 1.1 bits; conditional E-value: 4.8 SEEEEEEETTSSEEEEE...ETTSEEEEEE CS WD40 12 svtslafspdgawlasG...sdDgtvriWd 38 ++ + +s++ + l+++ s + ++ +Wd sp|P53197|CDH1_YEAST 473 QICNMVWSKNTNELVTShgyS-KYNLTLWD 501 378888*********984333.99999998 PP == domain 5 score: 19.3 bits; conditional E-value: 8.4e-06 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ +l+GH + v +l s dg+ ++sG D t+r W+ sp|P53197|CDH1_YEAST 506 DPIAILKGHsFRVLHLTLSNDGTTVVSGAGDETLRYWK 543 57899****555****************55*******5 PP >> sp|Q03177|YMZ2_YEAST WD repeat-containing protein YMR102C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) O # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.1 1.1e-07 6.6e-06 11 38 .] 174 201 .. 159 201 .. 0.85 2 ! 20.2 0.0 4.6e-06 0.00027 3 37 .. 270 304 .. 268 305 .. 0.87 3 ! 20.6 0.4 3.3e-06 0.0002 3 38 .] 311 347 .. 309 347 .. 0.84 4 ? 2.9 0.0 1.3 79 13 38 .] 428 457 .. 418 457 .. 0.65 5 ? 2.9 0.0 1.3 77 6 18 .. 577 590 .. 573 619 .. 0.84 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.1e-07 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 + ++s +fs+dg+++a+Gs+Dg++riW+ sp|Q03177|YMZ2_YEAST 174 KAIWSTKFSRDGKFMATGSKDGKIRIWK 201 349999*********************6 PP == domain 2 score: 20.2 bits; conditional E-value: 4.6e-06 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 +lr ++ H ++v ++ +s+++ l s+s+D+tv++W sp|Q03177|YMZ2_YEAST 270 PLRLYKEHvQDVLDINWSKNNFIL-SASMDKTVKLW 304 78999***999****999997776.6788******* PP == domain 3 score: 20.6 bits; conditional E-value: 3.3e-06 EEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 l+t+ H ++vt++ f+p + + +sG+ D+++r+W+ sp|Q03177|YMZ2_YEAST 311 SLKTFI-HpDFVTCVEFHPTDDRFfISGCLDHKCRLWS 347 577886.9788*****99999996269*9********5 PP == domain 4 score: 2.9 bits; conditional E-value: 1.3 EEEEE.....EETTSSEEEEEETTSEEEEEE CS WD40 13 vtsla.....fspdgawlasGsdDgtvriWd 38 vt+l+ + + ++++++ D +ri+d sp|Q03177|YMZ2_YEAST 428 VTGLQafrsqLDNSFRLVVTSN-DSRIRIFD 457 6666555543333335678766.******98 PP == domain 5 score: 2.9 bits; conditional E-value: 1.3 EEESS.SSEEEEEE CS WD40 6 tltGH.ssvtslaf 18 ++ +H +vt+++ sp|Q03177|YMZ2_YEAST 577 SFHAHnAPVTCVSI 590 68899777****74 PP >> sp|P13712|MSI1_YEAST Chromatin assembly factor 1 subunit p50 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.13 7.6 13 38 .] 120 158 .. 107 158 .. 0.76 2 ? 5.6 0.0 0.18 11 14 38 .] 204 229 .. 180 229 .. 0.77 3 ? 0.2 0.0 9.4 5.6e+02 12 29 .. 253 270 .. 234 276 .. 0.73 4 ! 10.7 0.0 0.0043 0.26 9 38 .] 294 325 .. 286 325 .. 0.79 5 ! 16.7 0.0 5.7e-05 0.0034 9 38 .] 338 370 .. 331 370 .. 0.80 6 ! 20.6 1.3 3.3e-06 0.0002 4 38 .] 377 413 .. 374 413 .. 0.82 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.13 EEEEE.EETTSSE...........EEEE.ETTSEEEEEE CS WD40 13 vtsla.fspdgaw...........lasG.sdDgtvriWd 38 v++++ f p+g +++G s Dg ++i+d sp|P13712|MSI1_YEAST 120 VNDISiFFPNGECnrarylpqnpdIIAGaSSDGAIYIFD 158 7777778888888888888888886667656******98 PP == domain 2 score: 5.6 bits; conditional E-value: 0.18 EEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 14 tslafspdgaw.......lasGsdDgtvriWd 38 tsl aw l+s++ +g v +Wd sp|P13712|MSI1_YEAST 204 TSL------AWnlqqealLLSSHSNGQVQVWD 229 455......334444444889*88*******9 PP == domain 3 score: 0.2 bits; conditional E-value: 9.4 SEEEEEEETTSSEEEEEE CS WD40 12 svtslafspdgawlasGs 29 v+++ + p ++ l++++ sp|P13712|MSI1_YEAST 253 AVNDVTWMPTHDSLFAAC 270 399998888888876543 PP == domain 4 score: 10.7 bits; conditional E-value: 0.0043 SS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasG.sdDgtvriWd 38 H ++v+s++f+ +++++++ + +g + +Wd sp|P13712|MSI1_YEAST 294 KHdGGVNSCRFNYKNSLILASaDSNGRLNLWD 325 59777******9999998655344*******9 PP == domain 5 score: 16.7 bits; conditional E-value: 5.7e-05 SS.SSEEEEEEETTSSEEE.EEE.TTSEEEEEE CS WD40 9 GH.ssvtslafspdgawla.sGs.dDgtvriWd 38 H +sv+ l +sp+ + ++ +++ +Dg v++Wd sp|P13712|MSI1_YEAST 338 EHgTSVSTLEWSPNFDTVLaTAGqEDGLVKLWD 370 48788************75266647*******9 PP == domain 6 score: 20.6 bits; conditional E-value: 3.3e-06 EEEEESS.SSEEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasG.sdDgtvriWd 38 + t GH +v++++++ + +wl+++ D++v+iW+ sp|P13712|MSI1_YEAST 377 IFTHGGHmLGVNDISWDAHDPWLMCSvANDNSVHIWK 413 5566799888*************966556*******6 PP >> sp|P39108|PEX7_YEAST Peroxisomal targeting signal 2 receptor OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.73 44 20 38 .] 72 89 .. 53 89 .. 0.68 2 ! 17.9 0.0 2.3e-05 0.0014 4 38 .] 97 133 .. 94 133 .. 0.75 3 ? 1.3 0.0 4.3 2.6e+02 13 31 .. 177 196 .. 164 203 .. 0.60 4 ! 16.3 0.0 7.7e-05 0.0046 3 38 .] 211 249 .. 209 249 .. 0.73 5 ! 16.1 0.3 8.5e-05 0.0051 8 37 .. 280 311 .. 270 312 .. 0.79 6 ? 7.4 0.4 0.048 2.9 6 38 .] 337 372 .. 333 372 .. 0.81 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.73 TTSSEEEEE.ETTSEEEEEE CS WD40 20 pdgawlasG.sdDgtvriWd 38 ++++ l+ + + Dgt+r++d sp|P39108|PEX7_YEAST 72 HENQVLV-AqG-DGTLRLFD 89 3333466.548.******98 PP == domain 2 score: 17.9 bits; conditional E-value: 2.3e-05 EEEEESS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 + +++ H v s+ +w ++s+s+Dg+++iW+ sp|P39108|PEX7_YEAST 97 IAIFKEHeREVFSC------NWnlvnrqnFLSSSWDGSIKIWS 133 67788885447777......6666666675689*********5 PP == domain 3 score: 1.3 bits; conditional E-value: 4.3 EEEEEEETTSSEEE.EEETT CS WD40 13 vtslafspdgawla.sGsdD 31 v+ +fsp+ + l+ s+s + sp|P39108|PEX7_YEAST 177 VYQAQFSPHDQNLVlSCSGN 196 54445666666654488644 PP == domain 4 score: 16.3 bits; conditional E-value: 7.7e-05 EEEEEESSSSEEEEE..EETTSSEEE.EEETTSEEEEEE CS WD40 3 clrtltGHssvtsla..fspdgawla.sGsdDgtvriWd 38 ++ + Hs+ +l f+++ ++++ +G+ D+ +riWd sp|P39108|PEX7_YEAST 211 NQNNFLVHSGLEALTcdFNKYRPYVVaTGGVDNAIRIWD 249 56666677665444444999999974499*********9 PP == domain 5 score: 16.1 bits; conditional E-value: 8.5e-05 ESSSS..EEEEEEETTSSEEE.EEETTSEEEEE CS WD40 8 tGHss..vtslafspdgawla.sGsdDgtvriW 37 +H + ++ + +sp+++ ++ s+s+D t+riW sp|P39108|PEX7_YEAST 280 NAH-GlaIRKVTWSPHHSNILmSASYDMTCRIW 311 478.34599999*******7559999******* PP == domain 6 score: 7.4 bits; conditional E-value: 0.048 EEESS.SSEEEEEEETTSSE........EEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgaw........lasGsdDgtvriWd 38 +t H +v + +w +as +Dg++ +W+ sp|P39108|PEX7_YEAST 337 NFTQHsEFVFGA------DWslwgkpgyVASTAWDGNLFVWN 372 577885558888......777778888899999********8 PP >> sp|Q06440|CORO_YEAST Coronin-like protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CRN1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.3 3.4e-05 0.0021 7 38 .] 77 110 .. 72 110 .. 0.89 2 ! 16.0 0.0 9.5e-05 0.0057 2 38 .] 131 169 .. 130 169 .. 0.78 3 ! 22.3 0.0 9.6e-07 5.8e-05 6 38 .] 178 210 .. 173 210 .. 0.85 4 ? 3.2 0.1 1 60 16 38 .] 231 257 .. 216 257 .. 0.75 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 3.4e-05 EESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 ++GH v + +f+p ++ +asGsdD ++ iWd sp|Q06440|CORO_YEAST 77 FRGHtAQVLDTDFDPFNDHrIASGSDDSKIGIWD 110 89**766*99999999999999***********9 PP == domain 2 score: 16.0 bits; conditional E-value: 9.5e-05 EEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 ++++ ltGH v ++ ++p + as+s D tv++W+ sp|Q06440|CORO_YEAST 131 KPVKFLTGHaRKVGHVLYHPVAENVlASSSGDYTVKLWN 169 688999***5449999888888886256666*******8 PP == domain 3 score: 22.3 bits; conditional E-value: 9.6e-07 EEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHss..vtslafspdgawlasGsdDgtvriWd 38 tl+ H + vts++fs dg++la+ +D+++r+W+ sp|Q06440|CORO_YEAST 178 TLK-H-PdmVTSMSFSYDGNYLATVARDKKLRVWN 210 555.7.346**************9999*******8 PP == domain 4 score: 3.2 bits; conditional E-value: 1 EEEETTSSEEE.EE.ET..TSEEEEEE CS WD40 16 lafspdgawla.sG.sd..DgtvriWd 38 + + +++ la +G s+ D+ + iWd sp|Q06440|CORO_YEAST 231 VVWLGNSDRLAtTGfSKlsDRQIGIWD 257 4577888889845663345*******9 PP >> sp|P39706|SWD1_YEAST COMPASS component SWD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SW # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.0 0.011 0.68 14 38 .] 30 54 .. 7 54 .. 0.77 2 ! 32.5 0.2 5.7e-10 3.4e-08 7 38 .] 68 100 .. 62 100 .. 0.92 3 ! 10.4 0.0 0.0057 0.34 2 37 .. 205 241 .. 204 242 .. 0.85 4 ? 1.8 0.0 3 1.8e+02 3 38 .] 304 341 .. 302 341 .. 0.72 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.011 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 +l+fsp g++la G+ +g + i+d sp|P39706|SWD1_YEAST 30 ECLQFSPCGDYLALGCANGALVIYD 54 59**********87888**999998 PP == domain 2 score: 32.5 bits; conditional E-value: 5.7e-10 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +H ++ts+a+spdg++l+++s+D ++++Wd sp|P39706|SWD1_YEAST 68 LGAHvRPITSIAWSPDGRLLLTSSRDWSIKLWD 100 6799889*************************9 PP == domain 3 score: 10.4 bits; conditional E-value: 0.0057 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriW 37 +c+++l+ s++ +l +s++g la +s D+t+r + sp|P39706|SWD1_YEAST 205 ECIHSLKITsSNIKHLIVSQNGERLAiNCS-DRTIRQY 241 699999977566************985699.*****86 PP == domain 4 score: 1.8 bits; conditional E-value: 3 EEEEEESS.SS.EEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 3 clrtltGH.ss.vtslafspdgawlas.GsdDgtvriWd 38 ++r+l+G + ++ ++ ++ ++s G + g+v++W+ sp|P39706|SWD1_YEAST 304 LVRVLEGAeEElI-DINWDFYSMSIVSnGFESGNVYVWS 341 6788888854455.88777777777754789*******5 PP >> sp|P36104|SWD2_YEAST COMPASS component SWD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SW # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.8 0.0 0.00097 0.058 4 33 .. 17 50 .. 14 55 .. 0.70 2 ! 22.3 0.0 9.5e-07 5.7e-05 2 38 .] 104 141 .. 103 141 .. 0.88 3 ? 3.0 0.0 1.2 70 14 29 .. 205 220 .. 194 227 .. 0.82 4 ! 11.7 0.0 0.0022 0.13 16 38 .] 256 278 .. 234 278 .. 0.89 5 ? 1.3 0.0 4 2.4e+02 9 29 .. 298 319 .. 290 327 .. 0.75 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00097 EEEEESS.SS...EEEEEEETTSSEEEEEETTSE CS WD40 4 lrtltGH.ss...vtslafspdgawlasGsdDgt 33 ++++ + ++ vtsl f+++g++l+++s + t sp|P36104|SWD2_YEAST 17 VKSFQPQeKDcgpVTSLNFDDNGQFLLTSSSNDT 50 5555545544566************998865655 PP == domain 2 score: 22.3 bits; conditional E-value: 9.5e-07 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 q lr ++GH+ v++l+ +p ++ ++s+s+D +vr+Wd sp|P36104|SWD2_YEAST 104 QYLRYFSGHGAlVNDLKMNPVNDTFLSSSYDESVRLWD 141 678889***557*****9999999999999*******9 PP == domain 3 score: 3.0 bits; conditional E-value: 1.2 EEEEEETTSSEEEEEE CS WD40 14 tslafspdgawlasGs 29 + l fs +g++l+ Gs sp|P36104|SWD2_YEAST 205 NKLEFSNNGKYLLVGS 220 5678********9997 PP == domain 4 score: 11.7 bits; conditional E-value: 0.0022 EEEETTSSEEEEE.ETTSEEEEEE CS WD40 16 lafspdgawlasG.sdDgtvriWd 38 +f pdg +++ G ++Dg + iW+ sp|P36104|SWD2_YEAST 256 ACFTPDGEFVL-GtDYDGRIAIWN 278 579********.8346*******8 PP == domain 5 score: 1.3 bits; conditional E-value: 4 SS.SSEEEEEEETTSSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGs 29 H ++ +s+af+p +++++++ sp|P36104|SWD2_YEAST 298 SHeTCPRSIAFNPKYSMFVTAD 319 565556899********99874 PP >> sp|Q04305|UTP15_YEAST U3 small nucleolar RNA-associated protein 15 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.1 0.38 23 8 25 .. 37 55 .. 31 67 .. 0.78 2 ? 5.3 0.0 0.22 13 3 38 .] 73 109 .. 71 109 .. 0.76 3 ! 13.2 0.1 0.00072 0.043 9 38 .] 124 153 .. 115 153 .. 0.79 4 ! 15.0 0.0 0.00019 0.011 2 38 .] 159 197 .. 158 197 .. 0.86 5 ? 3.6 0.1 0.76 46 10 38 .] 211 238 .. 201 238 .. 0.62 6 ! 12.1 0.0 0.0016 0.095 8 38 .] 248 285 .. 242 285 .. 0.69 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.38 ESSSSEEEEEEETTSSE.E CS WD40 8 tGHssvtslafspdgaw.l 25 + H+svt+++f+p ++ + sp|Q04305|UTP15_YEAST 37 KEHNSVTHISFNPQHPHdF 55 5799********9988762 PP == domain 2 score: 5.3 bits; conditional E-value: 0.22 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++t++ ++ v+s +f +dg++l++G+ g v ++d sp|Q04305|UTP15_YEAST 73 VIKTFSRFKDvVYSASFRSDGKLLCAGDATGLVSVYD 109 566776666756************9997777777776 PP == domain 3 score: 13.2 bits; conditional E-value: 0.00072 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 +H ++vt + +d++ la++sdD+ r+Wd sp|Q04305|UTP15_YEAST 124 THpTHVTKF-HTQDNKILATASDDRVTRLWD 153 576669888.5556666799**********9 PP == domain 4 score: 15.0 bits; conditional E-value: 0.00019 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 +++ +ltG + v+ l+f p + l+ +Gs+Dg +r++d sp|Q04305|UTP15_YEAST 159 EPQLELTGAtDYVRTLSFIPAAPHLVaTGSYDGLIRLYD 197 578899999555*****999999975499********98 PP == domain 5 score: 3.6 bits; conditional E-value: 0.76 S.SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssv.tslafspdgawlasGsdDgtvriWd 38 H ++v + +a+sp + ++s++ ++ ++Wd sp|Q04305|UTP15_YEAST 211 HdQPVeNVIAVSPTQ--IVSCG-GNNFKVWD 238 655553333344444..55899.*******9 PP == domain 6 score: 12.1 bits; conditional E-value: 0.0016 ESS..SSEEEEE.....EETTSSE...EEEEETTSEEEEEE CS WD40 8 tGH..ssvtsla.....fspdgaw...lasGsdDgtvriWd 38 +G + vt+l+ sp + l+++s Dg+v+++d sp|Q04305|UTP15_YEAST 248 RGNfnKAVTCLDyvenfDSP---MqsaLIASSLDGHVKVFD 285 4776445****877665333...2444777888******98 PP >> sp|Q06506|RRP9_YEAST Ribosomal RNA-processing protein 9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.0 3.7e-07 2.2e-05 6 38 .] 231 264 .. 225 264 .. 0.90 2 ? 3.4 0.0 0.9 54 13 35 .. 283 305 .. 270 308 .. 0.83 3 ? 7.4 0.0 0.049 2.9 4 38 .] 315 350 .. 312 350 .. 0.71 4 ? 6.1 0.2 0.13 7.8 23 38 .] 412 426 .. 397 426 .. 0.80 5 ! 11.1 0.1 0.0033 0.2 12 38 .] 474 500 .. 463 500 .. 0.88 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 3.7e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t +GH + + +a spdg+++++G++D+++ +W+ sp|Q06506|RRP9_YEAST 231 TTEGHyDEILTVAASPDGKYVVTGGRDRKLIVWS 264 456**888*************************5 PP == domain 2 score: 3.4 bits; conditional E-value: 0.9 EEEEEEETTSSEEEEEETTSEEE CS WD40 13 vtslafspdgawlasGsdDgtvr 35 v slaf ++++ l +++ D ++r sp|Q06506|RRP9_YEAST 283 VLSLAFRKNSDQLYASCADFKIR 305 899**********87766*9998 PP == domain 3 score: 7.4 bits; conditional E-value: 0.049 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 l +l GH + v +++ + ++ G +D+t ++W+ sp|Q06506|RRP9_YEAST 315 LEILYGHhDIVEDISALAMERCVTVGARDRTAMLWK 350 6678899444677754455555888*9********6 PP == domain 4 score: 6.1 bits; conditional E-value: 0.13 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++ ++Gsd+g++ +W+ sp|Q06506|RRP9_YEAST 412 HF-ITGSDNGNICLWS 426 34.58**********5 PP == domain 5 score: 11.1 bits; conditional E-value: 0.0033 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++tsl p+++ ++sGs+ g++++W+ sp|Q06506|RRP9_YEAST 474 WITSLYAIPYSNVFISGSWSGSLKVWK 500 48888888999999************6 PP >> sp|P53196|RPN14_YEAST 26S proteasome regulatory subunit RPN14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 8e-06 0.00048 5 38 .] 129 164 .. 125 164 .. 0.86 2 ! 22.4 0.0 8.9e-07 5.3e-05 2 37 .. 169 205 .. 168 206 .. 0.89 3 ? 3.5 0.1 0.83 50 10 30 .. 223 264 .. 210 316 .. 0.67 4 ? 3.1 0.0 1.1 67 12 36 .. 334 357 .. 323 357 .. 0.69 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 8e-06 EEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 r+++ +H s +t l+f p+g l+s+s D ++iW+ sp|P53196|RPN14_YEAST 129 REIDqAHvSEITKLKFFPSGEALISSSQDMQLKIWS 164 5554499999*************************5 PP == domain 2 score: 22.4 bits; conditional E-value: 8.9e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++ rtl GH vt++a + g+ ++s+s Dgt+r+W sp|P53196|RPN14_YEAST 169 SNPRTLIGHrATVTDIAIIDRGRNVLSASLDGTIRLW 205 56799****888*****9999999999999******* PP == domain 3 score: 3.5 bits; conditional E-value: 0.83 SSSEEEEE.....................EETTSSEEEEEET CS WD40 10 Hssvtsla.....................fspdgawlasGsd 30 H++v+s+a f +g+++++G+ sp|P53196|RPN14_YEAST 223 HDGVNSIAlfvgtdrqlheistskknnleFGTYGKYVIAGHV 264 555777754444444444444444444445555555555554 PP == domain 4 score: 3.1 bits; conditional E-value: 1.1 SEEEEEEETTSSEEEEEETTSEEEE CS WD40 12 svtslafspdgawlasGsdDgtvri 36 +++ + f +++sG D ++++ sp|P53196|RPN14_YEAST 334 PINNVYFAAGALFVSSGF-DTSIKL 357 577775555555666666.****97 PP >> sp|Q08924|WDR6_YEAST Regulator of Ty1 transposition protein 10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 0.1 1.3e-08 7.6e-07 3 38 .] 171 207 .. 169 207 .. 0.93 2 ! 12.0 1.2 0.0017 0.1 10 38 .] 220 249 .. 211 249 .. 0.73 3 ? 5.8 0.1 0.16 9.4 6 38 .] 265 299 .. 260 299 .. 0.86 4 ? 4.2 0.0 0.5 30 13 36 .. 657 691 .. 647 691 .. 0.74 5 ? 8.4 0.1 0.023 1.4 17 37 .. 770 794 .. 756 795 .. 0.73 6 ? 1.9 0.0 2.7 1.6e+02 5 32 .. 876 908 .. 873 910 .. 0.65 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 1.3e-08 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++ l GH +s+ + s +g+++as+sdD+++r+Wd sp|Q08924|WDR6_YEAST 171 KIHNLLGHeGSIFYVNLSNNGRYVASCSDDRSIRLWD 207 689999**999*99999*******************9 PP == domain 2 score: 12.0 bits; conditional E-value: 0.0017 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H ++ l f ++ + l+s s+D+t+r+W+ sp|Q08924|WDR6_YEAST 220 HtARIWNLMFFDNDSKLISVSEDCTCRVWN 249 6444888886666666678899*******8 PP == domain 3 score: 5.8 bits; conditional E-value: 0.16 EEESS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH..ssvtslafspdgawlasGsdDgtvriWd 38 +++ H +s++++++ +d ++++ Dg +++ d sp|Q08924|WDR6_YEAST 265 VYEVHliKSIWGVDVKDDEMIAVTSGNDGRLKLID 299 68899999*****99999999888888****9865 PP == domain 4 score: 4.2 bits; conditional E-value: 0.5 EEEEE...........EETTSSEEEEEETTSEEEE CS WD40 13 vtsla...........fspdgawlasGsdDgtvri 36 +++++ + +dg+ ++++s+D t+++ sp|Q08924|WDR6_YEAST 657 IRDISicpvsntntndNFKDGHIFCTASEDTTIKL 691 5555555666666666788999999********97 PP == domain 5 score: 8.4 bits; conditional E-value: 0.023 E...EETTSSEEE.EE.ETTSEEEEE CS WD40 17 a...fspdgawla.sG.sdDgtvriW 37 + s++g++l+ + s D t++iW sp|Q08924|WDR6_YEAST 770 DvkfISQSGDFLLvTVyS-DSTIKIW 794 34467999***8625556.******* PP == domain 6 score: 1.9 bits; conditional E-value: 2.7 EEEESS.SSEEEEE....EETTSSE....EEEEETTS CS WD40 5 rtltGH.ssvtsla....fspdgaw....lasGsdDg 32 l H s+v sl+ +++G+dD+ sp|Q08924|WDR6_YEAST 876 AQLPVHqSGVKSLDyvanAT----RtsatILTGGDDN 908 56778988899996444433....2444477899775 PP >> sp|Q00362|2ABA_YEAST Protein phosphatase PP2A regulatory subunit B OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.038 2.3 13 36 .. 28 51 .. 15 53 .. 0.84 2 ? 7.0 0.0 0.063 3.8 21 38 .] 98 114 .. 63 114 .. 0.72 3 ? 9.0 0.0 0.015 0.89 4 38 .] 176 211 .. 173 211 .. 0.82 4 ? 1.8 0.0 2.9 1.7e+02 13 36 .. 236 260 .. 227 262 .. 0.78 5 ! 17.9 0.0 2.4e-05 0.0014 11 38 .] 293 319 .. 278 319 .. 0.83 6 ? 2.3 0.0 2.1 1.2e+02 16 37 .. 355 376 .. 339 376 .. 0.89 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.038 EEEEEEETTSSEEEEEETTSEEEE CS WD40 13 vtslafspdgawlasGsdDgtvri 36 +t++ f+ g++la+G++ g v + sp|Q00362|2ABA_YEAST 28 ITAVEFDYTGNYLATGDKGGRVVL 51 9***************98777766 PP == domain 2 score: 7.0 bits; conditional E-value: 0.063 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 +++l+s D+t+++W+ sp|Q00362|2ABA_YEAST 98 RSHFLLSTN-DKTIKLWK 114 456689766.*******6 PP == domain 3 score: 9.0 bits; conditional E-value: 0.015 EEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 r+++ +H +++s++ ++d+ ++s++ D + +W+ sp|Q00362|2ABA_YEAST 176 KRIYSnAHtYHINSISLNSDQETFLSAD-DLRINLWN 211 56676588555*****999999999878.*******8 PP == domain 4 score: 1.8 bits; conditional E-value: 2.9 EEEEEEETTSSEEE..EEETTSEEEE CS WD40 13 vtslafspdgawla..sGsdDgtvri 36 +ts f+p l+ s+s +gt+++ sp|Q00362|2ABA_YEAST 236 ITSAEFHPQECNLFmySSS-KGTIKL 260 5777788888886445999.****98 PP == domain 5 score: 17.9 bits; conditional E-value: 2.4e-05 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ss+++++fsp+g+++a + d tv+iWd sp|Q00362|2ABA_YEAST 293 SSISDIKFSPNGRYIA-SRDYLTVKIWD 319 3499**********97.799*******9 PP == domain 6 score: 2.3 bits; conditional E-value: 2.1 EEEETTSSEEEEEETTSEEEEE CS WD40 16 lafspdgawlasGsdDgtvriW 37 + fs d++ +++Gs++++ +i+ sp|Q00362|2ABA_YEAST 355 VNFSGDSSSVMTGSYNNNFMIY 376 669***********99998886 PP >> sp|P39984|HAT2_YEAST Histone acetyltransferase type B subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.0 0.0 0.0017 0.1 6 37 .. 155 188 .. 150 189 .. 0.61 2 ? 7.2 0.0 0.056 3.4 15 38 .] 256 280 .. 235 280 .. 0.74 3 ! 21.7 0.1 1.4e-06 8.6e-05 2 38 .] 286 324 .. 285 324 .. 0.87 4 ? 8.6 0.0 0.02 1.2 6 37 .. 347 380 .. 342 381 .. 0.80 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.0017 EEESSSS...EEEEEEETTSSEEEEEETTSEEEEE CS WD40 6 tltGHss...vtslafspdgawlasGsdDgtvriW 37 tl+ H++ s+++ g++l sGsdD+tv +W sp|P39984|HAT2_YEAST 155 TLKFHKDngyALSFSTLVKGRLL-SGSDDHTVALW 188 55555222343345445555555.8********** PP == domain 2 score: 7.2 bits; conditional E-value: 0.056 EEEEETTSSE.EEEEETTSEEEEEE CS WD40 15 slafspdgaw.lasGsdDgtvriWd 38 lafs++++ la++++D v+++d sp|P39984|HAT2_YEAST 256 TLAFSHHSSNlLAAAGMDSYVYLYD 280 56655555551667788******98 PP == domain 3 score: 21.7 bits; conditional E-value: 1.4e-06 EEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 ++l++ +GH + v+ l ++ dg ++sGs D+ +++Wd sp|P39984|HAT2_YEAST 286 EPLHHMSGHeDAVNNLEfsTHVDGVVVSSGS-DNRLMMWD 324 79*******777*988866888888888999.*******9 PP == domain 4 score: 8.6 bits; conditional E-value: 0.02 EEESS.SSEEEEEEETTSSEEEEEE.TTSEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGs.dDgtvriW 37 + GH ssv++++ +p +wl+++ + + + +W sp|P39984|HAT2_YEAST 347 VHAGHrSSVNDFDLNPQIPWLVASAeEENILQVW 380 556**999************98664368888888 PP >> sp|P25569|GID7_YEAST Glucose-induced degradation protein 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.073 4.3 13 29 .. 327 343 .. 313 356 .. 0.81 2 ? 5.1 0.0 0.25 15 14 30 .. 366 393 .. 351 398 .. 0.81 3 ! 15.7 0.0 0.00012 0.0071 10 38 .] 660 687 .. 649 687 .. 0.74 4 ! 18.8 0.0 1.3e-05 0.00075 1 38 [] 691 741 .. 691 741 .. 0.83 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.073 EEEEEEETTSSEEEEEE CS WD40 13 vtslafspdgawlasGs 29 ++ l fsp+g++las++ sp|P25569|GID7_YEAST 327 IWFLTFSPNGKYLASAT 343 89999********9873 PP == domain 2 score: 5.1 bits; conditional E-value: 0.25 EEEE.........EETTSSEEEEE..ET CS WD40 14 tsla.........fspdgawlasG..sd 30 t+++ fspd+++l+++ s+ sp|P25569|GID7_YEAST 366 TCVSlsqsvlylmFSPDSRYLVACpfSE 393 6666778888999********9986665 PP == domain 3 score: 15.7 bits; conditional E-value: 0.00012 SSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtslafspdgawlasGsdDgtvriWd 38 H + ++s+ f +++++sGs+Dg+++iWd sp|P25569|GID7_YEAST 660 H-FiIRSC-FAYGNKLVMSGSEDGKIYIWD 687 3.237766.666777788***********9 PP == domain 4 score: 18.8 bits; conditional E-value: 1.3e-05 TEEEEEEESSSSE..EEEE...........EETTSSEEEEEETTSEEEEEE CS WD40 1 gqclrtltGHssv..tsla...........fspdgawlasGsdDgtvriWd 38 g+++ +l+GHs v +s + ++ d+ ++asG+dDg+++iW+ sp|P25569|GID7_YEAST 691 GNLVSVLSGHSTVmsNSTKpmgkncnvvasNPADKEMFASGGDDGKIKIWK 741 57889999**888555555888888888899999999*************6 PP >> sp|P40362|UTP18_YEAST U3 small nucleolar RNA-associated protein 18 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 0.0 3.1e-07 1.8e-05 9 37 .. 247 275 .. 240 276 .. 0.88 2 ? 1.3 0.0 4.1 2.5e+02 22 38 .] 479 495 .. 472 495 .. 0.89 3 ? 3.1 0.0 1.1 66 13 26 .. 518 531 .. 507 543 .. 0.78 4 ! 19.8 0.0 5.8e-06 0.00035 12 38 .] 564 590 .. 550 590 .. 0.85 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 3.1e-07 SSSSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GHssvtslafspdgawlasGsdDgtvriW 37 Hs + sl+f+p++++l++G++D+t+ri+ sp|P40362|UTP18_YEAST 247 SHSAIQSLSFHPSKPLLLTGGYDKTLRIY 275 5777************************8 PP == domain 2 score: 1.3 bits; conditional E-value: 4.1 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 ++wla Gs+ g v ++d sp|P40362|UTP18_YEAST 479 NRWLAVGSESGFVNLYD 495 78********9999998 PP == domain 3 score: 3.1 bits; conditional E-value: 1.1 EEEEEEETTSSEEE CS WD40 13 vtslafspdgawla 26 ++ l+fspdg+ l+ sp|P40362|UTP18_YEAST 518 ISNLQFSPDGQILC 531 78899******985 PP == domain 4 score: 19.8 bits; conditional E-value: 5.8e-06 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 vts+afsp+g +la G + g+vr+W+ sp|P40362|UTP18_YEAST 564 KVTSVAFSPSGGLLAVGNEQGKVRLWK 590 3****************9********6 PP >> sp|P40042|RRT13_YEAST Regulator of rDNA transcription protein 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.1 1.1e-07 6.9e-06 2 38 .] 2 39 .. 1 39 [. 0.90 2 ! 18.0 0.1 2.2e-05 0.0013 4 38 .] 66 99 .. 64 99 .. 0.81 3 ? 5.6 0.0 0.18 11 5 38 .] 106 139 .. 103 139 .. 0.76 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 1.1e-07 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +cl++l+GH + ++s ++++ + +s+s+D t+riWd sp|P40042|RRT13_YEAST 2 KCLYILSGHtDRIYSTIYDHERKRCISASMDTTIRIWD 39 8********666*99989999999999999*******9 PP == domain 2 score: 18.0 bits; conditional E-value: 2.2e-05 EEEEESS.SS..EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ss..vtslafspdgawlasGsdDgtvriWd 38 ++tl+GH +l + ++l+s+s Dg++r Wd sp|P40042|RRT13_YEAST 66 MYTLRGHrALvgLLGL----SDKFLVSASVDGSIRCWD 99 57999**533335899....889999***********9 PP == domain 3 score: 5.6 bits; conditional E-value: 0.18 EEEESS...SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH...ssvtslafspdgawlasGsdDgtvriWd 38 +++ H + +t+l + + l+sGs g + i+d sp|P40042|RRT13_YEAST 106 KHFFDHtqlNTITAL--HVSDEVLVSGS-EGLLNIYD 139 555557545569999..88888899***.99999998 PP >> sp|Q12021|RAD28_YEAST Radiation-sensitive protein 28 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.1 9.1e-05 0.0054 13 37 .. 60 84 .. 42 84 .. 0.86 2 ! 18.1 0.3 2.1e-05 0.0012 8 38 .] 192 224 .. 186 224 .. 0.73 3 ? 8.1 0.0 0.03 1.8 13 38 .] 290 316 .. 280 316 .. 0.79 4 ? 8.6 0.3 0.021 1.2 9 37 .. 357 386 .. 350 387 .. 0.80 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 9.1e-05 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 v++l+ ++ g+ l+ G+dDg++ iW sp|Q12021|RAD28_YEAST 60 VNCLDIDDTGQVLLGGGDDGSLSIW 84 9*************999******** PP == domain 2 score: 18.1 bits; conditional E-value: 2.1e-05 ESSSS.EEEEEEETTSSE.......EEEEETTSEEEEEE CS WD40 8 tGHss.vtslafspdgaw.......lasGsdDgtvriWd 38 + H+ +t l+ w +++Gs D+tv+iWd sp|Q12021|RAD28_YEAST 192 SHHKYgITTLK------WykadngmFFTGSNDKTVKIWD 224 556556****6......44444444789**********9 PP == domain 3 score: 8.1 bits; conditional E-value: 0.03 EEEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 13 vtslafspdgawlasG.sdDgtvriWd 38 + +++f+p ++++ ++ g v++Wd sp|Q12021|RAD28_YEAST 290 ILCCKFNPVREQIIACgDMEGGVKLWD 316 8899988888888655157*******9 PP == domain 4 score: 8.6 bits; conditional E-value: 0.021 SSSSEEEEE...EETTSSEEEEEETTSEEEEE CS WD40 9 GHssvtsla...fspdgawlasGsdDgtvriW 37 +H ++++ ++++g+ l+s ++Dg++ +W sp|Q12021|RAD28_YEAST 357 AH--LRCCSdivWNSEGSELCSVGMDGKLNVW 386 66..66666677*******998788******* PP >> sp|P26309|CDC20_YEAST APC/C activator protein CDC20 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5592 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 1.1 0.018 1 12 38 .] 303 329 .. 294 329 .. 0.88 2 ! 21.9 0.2 1.3e-06 7.7e-05 5 38 .] 379 413 .. 374 413 .. 0.86 3 ! 16.7 0.1 5.6e-05 0.0034 8 38 .] 424 458 .. 418 458 .. 0.78 4 ? 9.1 0.0 0.014 0.85 8 37 .. 522 552 .. 515 553 .. 0.79 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.018 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 ++s+ +s+d ++ G +Dg+ iWd sp|P26309|CDC20_YEAST 303 TICSVTWSDDDCHISIGKEDGNTEIWD 329 49************99*99*******9 PP == domain 2 score: 21.9 bits; conditional E-value: 1.3e-06 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t+ H + v++l++ +dg lasG+ D+tv+iWd sp|P26309|CDC20_YEAST 379 STWAEHtGEVCGLSYKSDGLQLASGGNDNTVMIWD 413 455679666*************************9 PP == domain 3 score: 16.7 bits; conditional E-value: 5.6e-05 ESS.SSEEEEEEETTSSEE.EEEE..TTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawl.asGs..dDgtvriWd 38 ++H v +l+++p+++ + asG+ D+++++W+ sp|P26309|CDC20_YEAST 424 KTHtAAVKALSWCPYSPNIlASGGgqTDKHIHFWN 458 689666************725775455*******8 PP == domain 4 score: 9.1 bits; conditional E-value: 0.014 ESS.SSEEEEEEETTSSEEEE.EETTSEEEEE CS WD40 8 tGH.ssvtslafspdgawlas.GsdDgtvriW 37 +H +++ + spdg+ la+ G+ D +++++ sp|P26309|CDC20_YEAST 522 HAHeARICCSQLSPDGTTLATvGG-DENLKFY 552 578666*8888********96267.9999987 PP >> sp|Q06679|UTP4_YEAST U3 small nucleolar RNA-associated protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.0 0.019 1.1 13 38 .] 46 80 .. 33 80 .. 0.85 2 ? 8.1 0.3 0.03 1.8 3 36 .. 133 167 .. 131 169 .. 0.86 3 ? 8.5 0.1 0.022 1.3 23 38 .] 199 214 .. 181 214 .. 0.77 4 ? 8.1 0.1 0.03 1.8 12 38 .] 237 266 .. 223 266 .. 0.76 5 ! 15.2 0.0 0.00017 0.01 4 35 .. 273 305 .. 270 308 .. 0.89 6 ? 4.4 0.1 0.44 27 10 36 .. 329 358 .. 324 403 .. 0.89 7 ? 1.7 0.1 3 1.8e+02 12 28 .. 427 443 .. 416 495 .. 0.84 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.019 EEEEEEETTSSE.........EEEE.ETTSEEEEEE CS WD40 13 vtslafspdgaw.........lasG.sdDgtvriWd 38 +tslafs+ ++ la G s +g++ iW+ sp|Q06679|UTP4_YEAST 46 ITSLAFSHKSNInkltpsdlrLAIGrS-NGNIEIWN 80 999999999999999999988999*66.*******8 PP == domain 2 score: 8.1 bits; conditional E-value: 0.03 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEE CS WD40 3 clrtltGHss.vtslafspdgawlasGsdDgtvri 36 +lr ++ s+ ++s++ +++++ l+ G+d+gtv + sp|Q06679|UTP4_YEAST 133 PLRNYDCNSGvIWSISINDSQDKLSVGCDNGTVVL 167 678888887757********************987 PP == domain 3 score: 8.5 bits; conditional E-value: 0.022 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++++ G+ Dg +riW+ sp|Q06679|UTP4_YEAST 199 DFVIGGCSDGRIRIWS 214 56776656*******5 PP == domain 4 score: 8.1 bits; conditional E-value: 0.03 S...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 s...vtslafspdgawlasGsdDgtvriWd 38 v+s+ + p + +asG+ g++++Wd sp|Q06679|UTP4_YEAST 237 EstlVWSVIYLPRTDQIASGDSTGSIKFWD 266 1456999999999999****66*******9 PP == domain 5 score: 15.2 bits; conditional E-value: 0.00017 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvr 35 +++++H +v +l ++ d+++++s++ D+++ sp|Q06679|UTP4_YEAST 273 NQSFKAHdADVLCLTTDTDNNYVFSAGVDRKIF 305 5799***888**************9999**996 PP == domain 6 score: 4.4 bits; conditional E-value: 0.44 S.SSEEEEE..EETTSSEEEEEETTSEEEE CS WD40 10 H.ssvtsla..fspdgawlasGsdDgtvri 36 H +++++++ s+ ++l+sG+ +t+ i sp|Q06679|UTP4_YEAST 329 HgNDIRAICayQSKGADFLVSGGVEKTLVI 358 666899999999999999999998888765 PP == domain 7 score: 1.7 bits; conditional E-value: 3 SEEEEEEETTSSEEEEE CS WD40 12 svtslafspdgawlasG 28 +++ ++ spdg+ l+ G sp|Q06679|UTP4_YEAST 427 NISTCSLSPDGQVLVVG 443 48788889999999877 PP >> sp|P38149|DUG2_YEAST Probable di- and tripeptidase DUG2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.083 5 10 38 .] 19 48 .. 11 48 .. 0.86 2 ! 19.7 0.0 6.5e-06 0.00039 9 38 .] 67 98 .. 53 98 .. 0.87 3 ? 2.6 0.0 1.6 96 17 37 .. 233 264 .. 215 265 .. 0.55 4 ? 7.8 0.0 0.036 2.2 23 38 .] 298 313 .. 288 313 .. 0.85 5 ? 6.8 0.1 0.075 4.5 15 38 .] 382 396 .. 322 396 .. 0.79 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.083 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgawlasGsdDgtvriWd 38 H +s+ s+ p +++l++Gs D ++ ++d sp|P38149|DUG2_YEAST 19 HaFSILSIVAFPKKRLLFAGSQDSKILVFD 48 77779999999***************9998 PP == domain 2 score: 19.7 bits; conditional E-value: 6.5e-06 SS..SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GH..ssvtslafspdgawlasGsdDgtvriWd 38 +H ssv +l s d ++l+sG+ D vriW+ sp|P38149|DUG2_YEAST 67 THtrSSVLCLTGSEDENFLFSGGADSLVRIWS 98 788788*************************5 PP == domain 3 score: 2.6 bits; conditional E-value: 1.6 E............EETTSSEEEEEETTSEEEEE CS WD40 17 a............fspdgawlasGsdDgtvriW 37 + +s + ++s++ Dg ++W sp|P38149|DUG2_YEAST 233 CprfnqllekssrTSGAEHIISSAG-DGISKLW 264 3555554444443333344466778.******* PP == domain 4 score: 7.8 bits; conditional E-value: 0.036 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++l +G Dg ++iWd sp|P38149|DUG2_YEAST 298 PFLYCGLTDGIIKIWD 313 67999955*******9 PP == domain 5 score: 6.8 bits; conditional E-value: 0.075 EEEEETTSSEEEEEETTSEEEEEE CS WD40 15 slafspdgawlasGsdDgtvriWd 38 s l++G+ Dg++ +Wd sp|P38149|DUG2_YEAST 382 S---------LLTGGSDGSLTLWD 396 2.........446766*******9 PP >> sp|Q06078|UTP21_YEAST U3 small nucleolar RNA-associated protein 21 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.44 26 15 37 .. 122 140 .. 107 141 .. 0.81 2 ? 1.1 0.0 4.7 2.8e+02 13 35 .. 298 320 .. 281 321 .. 0.67 3 ? 0.4 0.0 8.3 4.9e+02 5 34 .. 344 375 .. 341 377 .. 0.60 4 ? 2.2 0.2 2.2 1.3e+02 12 38 .] 461 488 .. 451 488 .. 0.77 5 ? 2.7 0.0 1.5 87 7 38 .] 498 530 .. 493 530 .. 0.81 6 ! 29.8 0.3 4.2e-09 2.5e-07 4 38 .] 578 613 .. 574 613 .. 0.88 7 ? 7.4 0.1 0.048 2.9 13 37 .. 628 654 .. 619 655 .. 0.78 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.44 EEEEETTSSEEEEEETTSEEEEE CS WD40 15 slafspdgawlasGsdDgtvriW 37 ++ g++l++++dD+++ i+ sp|Q06078|UTP21_YEAST 122 CI----FGDYLCASTDDNSIFIY 140 55....7999*99999****998 PP == domain 2 score: 1.1 bits; conditional E-value: 4.7 EEEEEEETTSSEEE.EEETTSEEE CS WD40 13 vtslafspdgawla.sGsdDgtvr 35 vt f ++ ++ sG+ D++++ sp|Q06078|UTP21_YEAST 298 VTQATFLNGQPIIVtSGG-DNSLK 320 777777777788873566.*9987 PP == domain 3 score: 0.4 bits; conditional E-value: 8.3 EEEESS.SSEEEEEEETTSSE.EEEEETTSEE CS WD40 5 rtltGH.ssvtslafspdgaw.lasGsdDgtv 34 r+ GH ++ + +af ++++ ++s+s+D+++ sp|Q06078|UTP21_YEAST 344 RSRGGHsQPPSYIAFADSQSHfMLSASKDRSL 375 55567855544445444444425699*9*986 PP == domain 4 score: 2.2 bits; conditional E-value: 2.2 S.EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 12 s.vtslafspdgaw.lasGsdDgtvriWd 38 + v s+a s+ g++ ++ Gs +g++ i++ sp|Q06078|UTP21_YEAST 461 GfVKSVAMSQCGNFgFI-GSSNGSITIYN 488 2499**********876.877****9997 PP == domain 5 score: 2.7 bits; conditional E-value: 1.5 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 ++ H+ vt+++ + ++ ++s++ Dg v ++d sp|Q06078|UTP21_YEAST 498 YKLHKRaVTGISLDGMNRKMVSCGLDGIVGFYD 530 6668455****99999999999999**997776 PP == domain 6 score: 29.8 bits; conditional E-value: 4.2e-09 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +r l GH + +t+++fsp+g+w++s+s D t+r Wd sp|Q06078|UTP21_YEAST 578 VRQLWGHsNRITAFDFSPEGRWIVSASLDSTIRTWD 613 45566**777*************************9 PP == domain 7 score: 7.4 bits; conditional E-value: 0.048 E.EEEEEETTSSEEEEEET.TSEEEEE CS WD40 13 v.tslafspdgawlasGsd.DgtvriW 37 v t ++fsp+g++la+ + + + iW sp|Q06078|UTP21_YEAST 628 VaTNVKFSPNGDLLATTHVtGNGICIW 654 668999********9986336666666 PP >> sp|P32330|DGR2_YEAST 2-deoxy-glucose resistant protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.2 1.4e-06 8.5e-05 11 38 .] 174 201 .. 165 201 .. 0.92 2 ! 10.4 0.1 0.0056 0.34 9 37 .. 278 306 .. 270 307 .. 0.76 3 ! 16.0 0.2 9.7e-05 0.0058 4 38 .] 314 349 .. 311 349 .. 0.76 4 ? 0.5 0.0 7.7 4.6e+02 10 38 .] 427 460 .. 386 460 .. 0.76 5 ? 2.7 0.1 1.5 90 6 21 .. 587 603 .. 582 611 .. 0.82 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 1.4e-06 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 +s++++ fs+dg++++ G++Dg++++W+ sp|P32330|DGR2_YEAST 174 NSICCCTFSHDGKYMVIGCKDGSLHLWK 201 569************************6 PP == domain 2 score: 10.4 bits; conditional E-value: 0.0056 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 H ++ + +s++g ++ ++s+D+t ++W sp|P32330|DGR2_YEAST 278 EHaLDILDANWSKNGFLI-TASMDKTAKLW 306 575558888899999998.5777******* PP == domain 3 score: 16.0 bits; conditional E-value: 9.7e-05 EEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 4 lrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 l+t+ H ++vts f+ d +++++G+ D+ +r+W+ sp|P32330|DGR2_YEAST 314 LKTF-VHpDFVTSAIfFPNDDRFIITGCLDHRCRLWS 349 5666.59788*77773666666678***********5 PP == domain 4 score: 0.5 bits; conditional E-value: 7.7 SSS.EEEEE.....EETTSSEEEEEETTSEEEEEE CS WD40 10 Hss.vtsla.....fspdgawlasGsdDgtvriWd 38 H++ +t+l+ ++++ +++++ D ++ i+d sp|P32330|DGR2_YEAST 427 HGPrITGLQcffskVDKNLRLIVTTN-DSKIQIFD 460 54468888777766677777777766.88888877 PP == domain 5 score: 2.7 bits; conditional E-value: 1.5 EEESS.SSEEEEEEETT CS WD40 6 tltGH.ssvtslafspd 21 ++ +H s+vt+ + pd sp|P32330|DGR2_YEAST 587 SFHAHnSPVTCASIAPD 603 6889*777***987776 PP >> sp|Q02793|SKI8_YEAST Antiviral protein SKI8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SK # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.9 0.4 0.00087 0.052 8 38 .] 13 42 .. 8 42 .. 0.80 2 ? 0.3 0.3 8.8 5.3e+02 14 38 .] 125 154 .. 118 154 .. 0.62 3 ! 11.4 0.0 0.0027 0.16 4 31 .. 226 253 .. 219 256 .. 0.82 4 ! 24.5 0.6 2e-07 1.2e-05 6 38 .] 287 319 .. 280 319 .. 0.89 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.00087 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++H ++ s+ s +++ +s+s Dg +++Wd sp|Q02793|SKI8_YEAST 13 KAHdADIFSV--SACNSFTVSCSGDGYLKVWD 42 5797778888..777888667877*******9 PP == domain 2 score: 0.3 bits; conditional E-value: 8.8 EEEEEETTSSE.....EEEEETTSEEEEEE CS WD40 14 tslafspdgaw.....lasGsdDgtvriWd 38 ++l++ +++ l++ + +gt +iW+ sp|Q02793|SKI8_YEAST 125 WALKWGASNDRllshrLVATDVKGTTYIWK 154 567666666663333334456699999995 PP == domain 3 score: 11.4 bits; conditional E-value: 0.0027 EEEEESS.SSEEEEEEETTSSEEEEEETT CS WD40 4 lrtltGH.ssvtslafspdgawlasGsdD 31 +++ +s++s++fsp g++la ++ D sp|Q02793|SKI8_YEAST 226 QHSMINNsNSIRSVKFSPQGSLLAIAH-D 253 6666666678**************999.6 PP == domain 4 score: 24.5 bits; conditional E-value: 2e-07 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 ++ +H s+v sl+f+++g l+s+++Dg++r+Wd sp|Q02793|SKI8_YEAST 287 EF-AHsSWVMSLSFNDSGETLCSAGWDGKLRFWD 319 44.89777*************************9 PP >> sp|Q04225|RRB1_YEAST Ribosome assembly protein RRB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5592 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 3.1 1.9e+02 2 20 .. 263 283 .. 262 301 .. 0.70 2 ! 16.6 0.1 6.1e-05 0.0037 10 38 .] 321 350 .. 313 350 .. 0.76 3 ? 3.4 1.0 0.92 55 22 38 .] 379 395 .. 356 395 .. 0.68 4 ! 19.3 0.0 8.4e-06 0.0005 2 38 .] 408 446 .. 407 446 .. 0.85 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 3.1 EEEEEEESSSSE..EEEEEET CS WD40 2 qclrtltGHssv..tslafsp 20 ++++t + H++v ++l++sp sp|Q04225|RRB1_YEAST 263 RPIHTVKNHGNVegYGLDWSP 283 6899*****889888995554 PP == domain 2 score: 16.6 bits; conditional E-value: 6.1e-05 SSSEEEEEEETTSSEE.E.EEETTSEEEEEE CS WD40 10 Hssvtslafspdgawl.a.sGsdDgtvriWd 38 +s+ ++++s+ + + a +G+ Dg +riWd sp|Q04225|RRB1_YEAST 321 NKSIEDIQWSRTESTVfAtAGC-DGYIRIWD 350 3789***999999997343456.*******9 PP == domain 3 score: 3.4 bits; conditional E-value: 0.92 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 g +lasG+d+gt +Wd sp|Q04225|RRB1_YEAST 379 GYLLASGDDNGTWGVWD 395 334889999***99998 PP == domain 4 score: 19.3 bits; conditional E-value: 8.4e-06 EEEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 q++ ++ H + +ts+af+p ++ Gs+D+tv +Wd sp|Q04225|RRB1_YEAST 408 QPVAQYDFHkGAITSIAFNPLDESIVaVGSEDNTVTLWD 446 67888999*555*****999999975379*********9 PP >> sp|P38328|ARPC1_YEAST Actin-related protein 2/3 complex subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 1.1 68 12 34 .. 21 44 .. 9 45 .. 0.79 2 ! 15.1 0.1 0.00018 0.011 5 37 .. 57 89 .. 54 90 .. 0.90 3 ? 0.1 0.0 9.9 5.9e+02 14 29 .. 111 126 .. 104 131 .. 0.87 4 ! 17.5 0.2 3.1e-05 0.0018 12 37 .. 151 180 .. 139 181 .. 0.82 5 ? 2.4 0.0 1.8 1.1e+02 24 37 .. 367 382 .. 343 383 .. 0.69 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 1.1 SEEEEEEETTSSEEE.EEETTSEE CS WD40 12 svtslafspdgawla.sGsdDgtv 34 +++s +fs+d++ la ++ D+ v sp|P38328|ARPC1_YEAST 21 PIYSHCFSQDKSILAvTCETDCLV 44 589999*******97577447755 PP == domain 2 score: 15.1 bits; conditional E-value: 0.00018 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 tl+ H + +t+++ s +g+ + ++s D++ ++W sp|P38328|ARPC1_YEAST 57 ATLKDHdKTITAVDISIHGRIV-TCSQDRNAYVW 89 68999*888************7.79********* PP == domain 3 score: 0.1 bits; conditional E-value: 9.9 EEEEEETTSSEEEEEE CS WD40 14 tslafspdgawlasGs 29 ts+ + p+g +a Gs sp|P38328|ARPC1_YEAST 111 TSVTWAPNGYKFAVGS 126 7999*****9999887 PP == domain 4 score: 17.5 bits; conditional E-value: 3.1e-05 S....EEEEEEETTSSEEEEEETTSEEEEE CS WD40 12 s....vtslafspdgawlasGsdDgtvriW 37 + +++l+++ +g +la+G+ Dg r++ sp|P38328|ARPC1_YEAST 151 PikstINCLSWHANGVLLAAGGTDGFMRVF 180 24446****************99**99987 PP == domain 5 score: 2.4 bits; conditional E-value: 1.8 E..EEEEETTSEEEEE CS WD40 24 w..lasGsdDgtvriW 37 ++s++ Dg++ i+ sp|P38328|ARPC1_YEAST 367 ItqVSSCGLDGKIVIY 382 244678888****997 PP >> sp|Q12523|YP247_YEAST WD repeat-containing protein YPL247C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.7 0.011 0.63 12 38 .] 245 272 .. 237 272 .. 0.72 2 ! 14.4 0.1 0.0003 0.018 7 38 .] 283 316 .. 277 316 .. 0.75 3 ! 23.7 0.3 3.6e-07 2.1e-05 3 38 .] 386 423 .. 384 423 .. 0.88 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.011 SEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 12 svtsla.fspdgawlasGsdDgtvriWd 38 ++ts++ + d ++++s+s D t+ +Wd sp|Q12523|YP247_YEAST 245 PITSFDwNTVDTNLIISSSIDTTCIVWD 272 489996444455558899*********9 PP == domain 2 score: 14.4 bits; conditional E-value: 0.0003 EESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 l +H s v +++f ++ l as++ Dg+vr++d sp|Q12523|YP247_YEAST 283 LIAHdSEVFDVRFLTKSTQLfASCGGDGSVRVFD 316 679*777****977777776356655******98 PP == domain 3 score: 23.7 bits; conditional E-value: 3.6e-07 EEEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 ++ l GH ssv++++++p ++ ++ s++dD+ v Wd sp|Q12523|YP247_YEAST 386 PILNLQGHgSSVNGIKWHPTKRNVLlSCGDDCQVLYWD 423 677899**999************6449999*******9 PP >> sp|P38968|SEC31_YEAST Protein transport protein SEC31 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 1 61 14 37 .. 66 89 .. 53 90 .. 0.79 2 ! 12.1 0.1 0.0016 0.096 5 38 .] 102 137 .. 98 137 .. 0.84 3 ? 7.7 0.1 0.039 2.3 18 38 .] 217 241 .. 194 241 .. 0.69 4 ! 19.7 0.1 6.5e-06 0.00039 3 38 .] 248 286 .. 246 286 .. 0.77 5 ? 0.9 0.0 5.7 3.4e+02 24 37 .. 635 648 .. 621 648 .. 0.80 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 1 EEEEEETTSSEEEEEE.TTSEEEEE CS WD40 14 tslafspdgawlasGs.dDgtvriW 37 ++l++s++++ +a G d+g++ ++ sp|P38968|SEC31_YEAST 66 NDLDWSHNNKIIA-GAlDNGSLELY 89 7999*******97.75479998876 PP == domain 2 score: 12.1 bits; conditional E-value: 0.0016 EEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 ++ H ssv ++f+ ++ lasG+ +g + iWd sp|P38968|SEC31_YEAST 102 ARFSNHsSSVKTVKFNAKQDNvLASGGNNGEIFIWD 137 56899*888*****9999999457999********9 PP == domain 3 score: 7.7 bits; conditional E-value: 0.039 EETTSSE.EE..EEET.TSEEEEEE CS WD40 18 fspdgaw.la..sGsd.DgtvriWd 38 ++p ++ +a +Gsd D+++ iWd sp|P38968|SEC31_YEAST 217 WHPKNSTrVAtaTGSDnDPSILIWD 241 66666665542278877*******9 PP == domain 4 score: 19.7 bits; conditional E-value: 6.5e-06 EEEEEE.SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtlt.GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +l+tl GH +++ sl++++ l+s+++D+tv +W+ sp|P38968|SEC31_YEAST 248 PLQTLNqGHqKGILSLDWCHQDEHlLLSSGRDNTVLLWN 286 6778755**999****955555552679999*******8 PP == domain 5 score: 0.9 bits; conditional E-value: 5.7 EEEEEETTSEEEEE CS WD40 24 wlasGsdDgtvriW 37 +la+Gs D+ iW sp|P38968|SEC31_YEAST 635 YLAAGSLDKVASIW 648 699**********9 PP >> sp|Q08281|RTC1_YEAST Restriction of telomere capping protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.1 0.00037 0.022 5 38 .] 252 287 .. 248 287 .. 0.77 2 ! 20.5 0.0 3.5e-06 0.00021 5 37 .. 363 396 .. 359 396 .. 0.85 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.00037 EEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS WD40 5 rtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 ++l H s++s++ + ++++++sG+ D v+iWd sp|Q08281|RTC1_YEAST 252 TSLCEHtRSINSFDfNMVESNLIISGGQDSCVKIWD 287 456678666999976666666689***********9 PP == domain 2 score: 20.5 bits; conditional E-value: 3.5e-06 EEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ss.vtslafspdgawlasGsdDgtvriW 37 ++l +H ++ +l ++p++ ++a+G++Dg++ +W sp|Q08281|RTC1_YEAST 363 KKLNAHtGPgL-CLNWHPNQEYIATGGRDGKCCLW 396 56778844456.*********************** PP >> sp|P50082|AMA1_YEAST Meiosis-specific APC/C activator protein AMA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.054 3.2 12 29 .. 273 292 .. 261 301 .. 0.79 2 ! 13.2 0.0 0.00074 0.044 6 38 .] 385 418 .. 380 418 .. 0.87 3 ! 11.3 0.1 0.0028 0.17 10 37 .. 433 464 .. 424 465 .. 0.74 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.054 S..EEEEEEETTSSEEEEEE CS WD40 12 s..vtslafspdgawlasGs 29 vt+++f+p++++++ G+ sp|P50082|AMA1_YEAST 273 RdlVTCVSFCPYNTYFIVGT 292 1569***********99886 PP == domain 2 score: 13.2 bits; conditional E-value: 0.00074 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 t+ ++ + v++++ + + ++la G+ D+++ +Wd sp|P50082|AMA1_YEAST 385 TYQAQaQQVCGISLNEHANLLAVGGNDNSCSLWD 418 57777667*************************9 PP == domain 3 score: 11.3 bits; conditional E-value: 0.0028 S.SSEEEEEEETTSSEE.EEE..ETTSEEEEE CS WD40 10 H.ssvtslafspdgawl.asG..sdDgtvriW 37 H v ++af+p ++ l a+G s+D+ +++W sp|P50082|AMA1_YEAST 433 HkAAVKAIAFCPWSKSLlATGggSKDRCIKFW 464 7445999998888888625764479******* PP >> sp|P53962|YND5_YEAST Uncharacterized WD repeat-containing protein YNL035C OS=Saccharomyces cerevisiae (strain ATCC 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 7.5 4.5e+02 14 36 .. 17 40 .. 14 44 .. 0.83 2 ! 18.0 0.5 2.2e-05 0.0013 3 38 .] 139 177 .. 137 177 .. 0.81 3 ! 13.3 0.0 0.00065 0.039 9 37 .. 289 320 .. 281 321 .. 0.74 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 7.5 EEEEEETTSSE.EEEE.ETTSEEEE CS WD40 14 tslafspdgaw.lasG.sdDgtvri 36 ++l+ +p+ + l++G s +g +r+ sp|P53962|YND5_YEAST 17 WCLKLQPSYKHgLLTGlS-NGEIRL 40 688888888888889*88.**9998 PP == domain 2 score: 18.0 bits; conditional E-value: 2.2e-05 EEEEEE.SS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 3 clrtlt.GH.ssvtslafspdgawla.sGsdDgtvriWd 38 +lr+l H ++vt+++f+p+ ++ sGs Dg i+d sp|P53962|YND5_YEAST 139 PLRSLIdSHhDDVTCIKFHPSDVNILlSGSTDGYTNIYD 177 677764366699************644******999987 PP == domain 3 score: 13.3 bits; conditional E-value: 0.00065 SSSS..EEEEE.EETTSSEEEEEETTSEEEEE CS WD40 9 GHss..vtsla.fspdgawlasGsdDgtvriW 37 +H++ v+++ +++++l s+++Dg v+iW sp|P53962|YND5_YEAST 289 AHGDevVRDIFiPAQHSNMLYSCGEDGCVKIW 320 664455577765666778899*********** PP >> sp|Q12510|CMR1_YEAST DNA damage-binding protein CMR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 5.1 3e+02 21 35 .. 254 267 .. 233 268 .. 0.68 2 ! 13.0 0.0 0.00082 0.049 13 38 .] 336 362 .. 327 362 .. 0.84 3 ? 9.2 0.1 0.013 0.79 12 38 .] 392 418 .. 377 418 .. 0.76 4 ? 2.1 0.1 2.3 1.4e+02 16 34 .. 490 508 .. 475 518 .. 0.73 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 5.1 TSSEEEEEETTSEEE CS WD40 21 dgawlasGsdDgtvr 35 ++ l+++ Dg++r sp|Q12510|CMR1_YEAST 254 TSKILLTSY-DGSIR 267 344467877.****8 PP == domain 2 score: 13.0 bits; conditional E-value: 0.00082 EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 13 vtslafspdgaw.lasGsdDgtvriWd 38 + s+a +p ++ +a+Gs D+t++iWd sp|Q12510|CMR1_YEAST 336 IGSMAINPMRPYeIATGSLDRTLKIWD 362 556777777788899***********9 PP == domain 3 score: 9.2 bits; conditional E-value: 0.013 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 sv+++++sp l++ ++D t+r++d sp|Q12510|CMR1_YEAST 392 SVSAVSYSPTDGTLVCNGYDDTIRLFD 418 3899998888888885467******98 PP == domain 4 score: 2.1 bits; conditional E-value: 2.3 EEEETTSSEEEEE.ETTSEE CS WD40 16 lafspdgawlasG.sdDgtv 34 ++++p +w+a G s g++ sp|Q12510|CMR1_YEAST 490 ISWHPLRNWIAGGnS-SGKI 508 57*******984443.5555 PP >> sp|P21304|PWP1_YEAST Periodic tryptophan protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 1.5 92 23 38 .] 228 243 .. 211 243 .. 0.86 2 ! 16.4 0.6 7.2e-05 0.0043 5 38 .] 279 315 .. 275 315 .. 0.67 3 ? 7.7 0.0 0.041 2.4 2 38 .] 413 452 .. 412 452 .. 0.71 4 ? 2.7 0.0 1.5 90 23 38 .] 491 505 .. 475 505 .. 0.83 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 1.5 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++ a G+ D+ + iW+ sp|P21304|PWP1_YEAST 228 NYAAIGTFDPQIEIWN 243 56677988*******8 PP == domain 2 score: 16.4 bits; conditional E-value: 7.2e-05 EEEESS.SS.EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 5 rtltGH.ss.vtslafspdgaw.lasGsdDgtvriWd 38 +++t+H ++ v s+a +++ + las s D+tv++Wd sp|P21304|PWP1_YEAST 279 GHITTHhTDaVLSMAHNKYFRSvLASTSADHTVKLWD 315 45555554458888755555553566689*******9 PP == domain 3 score: 7.7 bits; conditional E-value: 0.041 EEEEEEESS.SSEEEEE.EETTSSE....EEEE..ETTSEEEEEE CS WD40 2 qclrtltGH.ssvtsla.fspdgaw....lasG..sdDgtvriWd 38 ++++tl++H +++ l+ + ++ +++G + +tv++W+ sp|P21304|PWP1_YEAST 413 KPVWTLKAHdAGISTLCsN----KFipgmMSTGamG-EKTVKLWK 452 7999*****7779888532....2234436788644.*******6 PP == domain 4 score: 2.7 bits; conditional E-value: 1.5 SEEEEEETTSEEEEEE CS WD40 23 awlasGsdDgtvriWd 38 ++++ G+ ++ +++Wd sp|P21304|PWP1_YEAST 491 TMVI-GGVNKVLKLWD 505 5555.999*******9 PP >> sp|Q02931|UTP17_YEAST NET1-associated nuclear protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.3 3.6e-05 0.0022 5 37 .. 291 324 .. 288 325 .. 0.91 2 ? 4.9 0.0 0.31 18 13 27 .. 495 509 .. 486 532 .. 0.77 3 ? 5.3 0.2 0.23 14 9 32 .. 605 629 .. 593 632 .. 0.76 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 3.6e-05 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvriW 37 r l+ H +sv sl+fs+dg++l+sG++ + +W sp|Q02931|UTP17_YEAST 291 RLLKWHiDSVLSLSFSHDGSYLLSGGWEKVMSLW 324 55788*999********************99999 PP == domain 2 score: 4.9 bits; conditional E-value: 0.31 EEEEEEETTSSEEEE CS WD40 13 vtslafspdgawlas 27 +t+l+f +dg+w+++ sp|Q02931|UTP17_YEAST 495 ITDLKFTKDGQWMIT 509 7***********765 PP == domain 3 score: 5.3 bits; conditional E-value: 0.23 SS..SSEEEEEEETTSSEEEEEETTS CS WD40 9 GH..ssvtslafspdgawlasGsdDg 32 H +sv sla+s+dg++++ G dD+ sp|Q02931|UTP17_YEAST 605 NHfsNSV-SLAWSQDGSLIFHGFDDK 629 5765669.**********99888554 PP >> sp|P53851|TEX1_YEAST Protein TEX1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TEX1 PE=1 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.1 0.33 20 11 37 .. 64 90 .. 46 90 .. 0.65 2 ? 6.4 0.0 0.1 6 3 37 .. 151 187 .. 149 188 .. 0.72 3 ? 2.8 0.5 1.4 84 11 30 .. 209 229 .. 189 235 .. 0.77 4 ! 16.9 0.1 4.8e-05 0.0029 7 38 .] 249 281 .. 244 281 .. 0.90 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.33 SSEEEEEEETTSSEEEEEET......TSEEEEE CS WD40 11 ssvtslafspdgawlasGsd......DgtvriW 37 + + sl ++++sGs Dg++ +W sp|P53851|TEX1_YEAST 64 NEILSL------KFHVSGSSmaysrmDGSLTVW 90 338899......66677652233445****999 PP == domain 2 score: 6.4 bits; conditional E-value: 0.1 EEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 3 clrtlt.GH.ssvtslafspdgawlasGsdDgtvriW 37 +lrtl+ G + v+ + ++p g+wl+++++ +++++ sp|P53851|TEX1_YEAST 151 KLRTLSlGSkTKVNTCLYDPLGNWLLAATKSEKIYLF 187 57777778755595555********999876666665 PP == domain 3 score: 2.8 bits; conditional E-value: 1.4 SS.EEEEEEETTSSEEEEEET CS WD40 11 ss.vtslafspdgawlasGsd 30 ++ v+sla+s g+ ++ G + sp|P53851|TEX1_YEAST 209 NDvVYSLAWSNGGSHIFIGFK 229 45569999****999987864 PP == domain 4 score: 16.9 bits; conditional E-value: 4.8e-05 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 +++H +++t ++ +p g+ +++Gs Dg++++W+ sp|P53851|TEX1_YEAST 249 IKAHtGPITEIKMDPWGRNFITGSIDGNCYVWN 281 489*888*************************8 PP >> sp|P43601|ATG18_YEAST Autophagy-related protein 18 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.0 0.0006 0.036 2 34 .. 236 269 .. 235 274 .. 0.87 2 ! 13.1 0.0 0.00075 0.045 9 37 .. 287 317 .. 278 318 .. 0.79 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.0006 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtv 34 q++ ++++H + + ++a s dg+++a++sd+gt+ sp|P43601|ATG18_YEAST 236 QPTMVIEAHkGEIAAMAISFDGTLMATASDKGTI 269 6788899**555*****************98887 PP == domain 2 score: 13.1 bits; conditional E-value: 0.00075 SS..SSEEEEEEETTSSEEE.EEETTSEEEEE CS WD40 9 GH..ssvtslafspdgawla.sGsdDgtvriW 37 G + ++s++fs d+++la +Gs +tv+i+ sp|P43601|ATG18_YEAST 287 GTyaTRIYSISFSEDSQYLAvTGS-SKTVHIF 317 5543449***********976999.*****97 PP >> sp|P38915|SPT8_YEAST Transcription factor SPT8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.12 7.1 9 38 .] 176 203 .. 170 203 .. 0.81 2 ? 5.3 0.0 0.22 13 9 38 .] 305 335 .. 295 335 .. 0.70 3 ? 5.4 0.0 0.2 12 25 38 .] 432 445 .. 418 445 .. 0.76 4 ? 5.4 0.0 0.21 13 9 32 .. 509 530 .. 497 535 .. 0.76 5 ? 3.8 0.1 0.68 41 6 29 .. 556 581 .. 551 595 .. 0.74 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.12 SSSSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 9 GHssvtslafspdgawla.sGsdDgtvriWd 38 +H v++la+s+ ++l+ Gs Dg +r +d sp|P38915|SPT8_YEAST 176 TH--VNALAVSRGLKYLFlGGS-DGYIRKYD 203 57..9****9******853667.****9665 PP == domain 2 score: 5.3 bits; conditional E-value: 0.22 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 GH+ v+ l+ + + ++sGs+D+ + Wd sp|P38915|SPT8_YEAST 305 GHTQiVNILRLNGQEDRFLSGSWDKRLLEWD 335 88443566655555666679*****999887 PP == domain 3 score: 5.4 bits; conditional E-value: 0.2 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 +++++ +g+v+iWd sp|P38915|SPT8_YEAST 432 FMTSGLNGSVHIWD 445 455666*******9 PP == domain 4 score: 5.4 bits; conditional E-value: 0.21 SSSSEEEEEEETTSSEEEEEETTS CS WD40 9 GHssvtslafspdgawlasGsdDg 32 G +v++++ p+++ l+++s+D+ sp|P38915|SPT8_YEAST 509 G--PVSCVKAMPNNKHLLCASRDN 530 3..49*************99*664 PP == domain 5 score: 3.8 bits; conditional E-value: 0.68 EEESS.SS.EEEEEEETTSSEEEEEE CS WD40 6 tltGH.ss.vtslafspdgawlasGs 29 + GH ++ ++ l +p +++++s s sp|P38915|SPT8_YEAST 556 IVPGHhGGiISNLYLDPTSRFIISTS 581 5679976667***********98643 PP >> sp|P26449|BUB3_YEAST Cell cycle arrest protein BUB3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5592 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.47 28 13 37 .. 14 38 .. 3 39 .. 0.84 2 ? 3.2 0.0 1 61 13 36 .. 104 126 .. 88 128 .. 0.77 3 ! 16.5 0.0 6.6e-05 0.004 12 38 .] 253 279 .. 234 279 .. 0.78 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.47 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 +++++ p++++l+ s+Dg++ ++ sp|P26449|BUB3_YEAST 14 ISDIKIIPSKSLLLITSWDGSLTVY 38 89999999****9999*****9776 PP == domain 2 score: 3.2 bits; conditional E-value: 1 EEEEEEETTSSEEEEEETTSEEEE CS WD40 13 vtslafspdgawlasGsdDgtvri 36 ++ ++ d +++a +s+Dg + + sp|P26449|BUB3_YEAST 104 ICRICKYGDDKLIA-ASWDGLIEV 126 67777777888876.8****9987 PP == domain 3 score: 16.5 bits; conditional E-value: 6.6e-05 SEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 svtslafspdgawlasGsdDgtvriWd 38 +v+s+ fsp +++l +++ Dg + W+ sp|P26449|BUB3_YEAST 253 PVNSIEFSPRHKFLYTAGSDGIISCWN 279 39************86544*******8 PP >> sp|P38163|SRO77_YEAST Lethal(2) giant larvae protein homolog SRO77 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 0.1 0.0084 0.51 11 38 .] 125 152 .. 105 152 .. 0.79 2 ? 5.2 0.0 0.25 15 14 38 .] 242 265 .. 228 265 .. 0.87 3 ? 8.9 0.0 0.016 0.96 25 38 .] 476 489 .. 463 489 .. 0.85 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.0084 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 +s+t++ ++p+ +w++ G + g++ i+d sp|P38163|SRO77_YEAST 125 NSITCIETDPSLDWMLIGLESGSILIYD 152 45************999*99******98 PP == domain 2 score: 5.2 bits; conditional E-value: 0.25 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 sl ++p++ +++ ++D+++ +Wd sp|P38163|SRO77_YEAST 242 QSL-YHPNSLHILTVHEDNSLVFWD 265 555.899999**************9 PP == domain 3 score: 8.9 bits; conditional E-value: 0.016 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 l++G+ +g+vriWd sp|P38163|SRO77_YEAST 476 LLTGHSNGSVRIWD 489 568*88*******9 PP >> sp|P25365|SED4_YEAST Putative guanine nucleotide-exchange factor SED4 OS=Saccharomyces cerevisiae (strain ATCC 20450 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 9.7 5.8e+02 13 26 .. 171 184 .. 161 202 .. 0.76 2 ? 5.9 0.0 0.15 8.8 11 34 .. 262 285 .. 247 287 .. 0.76 3 ! 13.7 0.0 0.00049 0.03 6 35 .. 299 329 .. 295 330 .. 0.85 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 9.7 EEEEEEETTSSEEE CS WD40 13 vtslafspdgawla 26 v++l f p+g +l+ sp|P25365|SED4_YEAST 171 VNDLHFAPNGILLS 184 99********9973 PP == domain 2 score: 5.9 bits; conditional E-value: 0.15 SSEEEEEEETTSSEEE.EEETTSEE CS WD40 11 ssvtslafspdgawla.sGsdDgtv 34 +++ts+++sp+++++a s+ D+ v sp|P25365|SED4_YEAST 262 NGITSMDVSPNKKFVAlSSN-DNLV 285 45************974554.8755 PP == domain 3 score: 13.7 bits; conditional E-value: 0.00049 EEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 6 tltGH.ssvtslafspdgawlasGsdDgtvr 35 + + H s +t + fspd+++las s+ +t+ sp|P25365|SED4_YEAST 299 VPRVHeSTITKVTFSPDSRYLASTSMGNTIN 329 56789888**************999888886 PP >> sp|P40055|UTP7_YEAST U3 small nucleolar RNA-associated protein 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.1 0.89 53 4 29 .. 184 209 .. 181 260 .. 0.57 2 ! 16.4 0.0 6.9e-05 0.0042 11 38 .] 275 302 .. 265 302 .. 0.84 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.89 EEEEESSSSE..EEEEEETTSSEEEEEE CS WD40 4 lrtltGHssv..tslafspdgawlasGs 29 l+ l+ H + ++l+f p++ +l++++ sp|P40055|UTP7_YEAST 184 LHRLKQH--IeaRHLDFLPYHYLLVTAG 209 6677777..6557777777777777644 PP == domain 2 score: 16.4 bits; conditional E-value: 6.9e-05 SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 11 ssvtslafspdgawlasGsdDgtvriWd 38 ++v+s+a +++g ++a+ + D++ +iWd sp|P40055|UTP7_YEAST 275 GPVNSIAIDRSGYYMATTGADRSMKIWD 302 56*************97777*******9 PP >> sp|P38873|KOG1_YEAST Target of rapamycin complex 1 subunit KOG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.2 0.0 0.0015 0.089 9 37 .. 1250 1283 .. 1241 1284 .. 0.77 2 ? 4.7 0.1 0.36 22 22 38 .] 1365 1381 .. 1330 1381 .. 0.72 3 ? 1.9 0.0 2.7 1.6e+02 25 38 .] 1418 1431 .. 1396 1431 .. 0.74 4 ? 0.3 0.0 8.7 5.2e+02 13 37 .. 1459 1481 .. 1444 1482 .. 0.76 5 ? 1.4 0.1 3.8 2.3e+02 13 37 .. 1522 1547 .. 1485 1548 .. 0.71 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.0015 SS.SS..EEEEE..EETTSSEEEEEETTSEEEEE CS WD40 9 GH.ss..vtsla..fspdgawlasGsdDgtvriW 37 G ++ vt+l+ + +d+a+l++Gs Dg ++i+ sp|P38873|KOG1_YEAST 1250 GTpFGtkVTDLKliNEDDSALLLTGSSDGVIKIY 1283 44323569999999***********99******8 PP == domain 2 score: 4.7 bits; conditional E-value: 0.36 SSEEEEEETTSEEEEEE CS WD40 22 gawlasGsdDgtvriWd 38 g+ +++G Dg++r++d sp|P38873|KOG1_YEAST 1365 GNIFVAGFADGSLRVYD 1381 444678988******98 PP == domain 3 score: 1.9 bits; conditional E-value: 2.7 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 l+sG +g v +Wd sp|P38873|KOG1_YEAST 1418 LVSGATNGVVELWD 1431 889*88*******9 PP == domain 4 score: 0.3 bits; conditional E-value: 8.7 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 t+++++ + + +a+G + ++iW sp|P38873|KOG1_YEAST 1459 MTCMQVHEHAPIIATG--TKQIKIW 1481 5899999999999876..8999999 PP == domain 5 score: 1.4 bits; conditional E-value: 3.8 EEEEEEETTSSEEEEE.ETTSEEEEE CS WD40 13 vtslafspdgawlasG.sdDgtvriW 37 +s+af+p+ ++a+ s D v i+ sp|P38873|KOG1_YEAST 1522 LSSMAFHPHRMMIAATnSHDSIVNIY 1547 56777999999998656669999987 PP >> sp|Q03897|WDR59_YEAST Maintenance of telomere capping protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.8 9.1 5.5e+02 12 38 .] 67 97 .. 60 97 .. 0.74 2 ! 12.4 0.2 0.0013 0.079 6 38 .] 109 143 .. 105 143 .. 0.81 3 ? 0.1 0.6 10 6e+02 21 38 .] 170 186 .. 154 186 .. 0.73 4 ! 23.4 0.2 4.2e-07 2.5e-05 3 38 .] 193 230 .. 191 230 .. 0.84 5 ? 2.0 0.3 2.5 1.5e+02 2 37 .. 292 338 .. 291 338 .. 0.61 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 9.1 S..EEEEEEETTSSE...EEEEETTSEEEEEE CS WD40 12 s..vtslafspdgaw...lasGsdDgtvriWd 38 + v ++++sp+ a ++s s +++ iW+ sp|Q03897|WDR59_YEAST 67 PwqVADVQWSPHPAKpywIVSTS-NQKAIIWN 97 44577887777777777899889.99999998 PP == domain 2 score: 12.4 bits; conditional E-value: 0.0013 EEESSSS.EEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 6 tltGHss.vtslafspdgaw.lasGsdDgtvriWd 38 +l GHs +t++ f+p ++ la++s D v+ Wd sp|Q03897|WDR59_YEAST 109 VLHGHSRaITDINFNPQHPDvLATCSVDTYVHAWD 143 678**446****977777774689**********9 PP == domain 3 score: 0.1 bits; conditional E-value: 10 TSSEEEEEETTSEEEEEE CS WD40 21 dgawlasGsdDgtvriWd 38 d + las++ + + +Wd sp|Q03897|WDR59_YEAST 170 DPNVLASSH-GNDIFVWD 186 444466666.*******9 PP == domain 4 score: 23.4 bits; conditional E-value: 4.2e-07 EEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS WD40 3 clrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 +l +l+GH ssv+s++f++ + ++s+s Dgtv++Wd sp|Q03897|WDR59_YEAST 193 PLCSLKGHvSSVNSIDFNRFKYSeIMSSSNDGTVKFWD 230 7889***********755555558889999*******9 PP == domain 5 score: 2.0 bits; conditional E-value: 2.5 EEEEEEESSSS.EEEEE....EETTSSE......EEEE.ETTSEEEEE CS WD40 2 qclrtltGHss.vtsla....fspdgaw......lasG.sdDgtvriW 37 q+++ ++GHs+ v ++ dg++ l+ s+D+ +++W sp|Q03897|WDR59_YEAST 292 QPIYAFKGHSDrVIDFLwrsrHTCDGDYddrefqLV-TwSKDCDLKLW 338 78889999*666657732333333444466666666.44778888888 PP >> sp|Q99247|YO087_YEAST Uncharacterized WD repeat-containing protein YOL087C OS=Saccharomyces cerevisiae (strain ATCC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 4.2 2.5e+02 20 35 .. 35 50 .. 16 52 .. 0.75 2 ? 8.9 0.0 0.016 0.97 10 37 .. 161 190 .. 155 191 .. 0.85 3 ! 10.1 0.1 0.0069 0.42 7 38 .] 264 296 .. 258 296 .. 0.63 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 4.2 TTSSEEEEEETTSEEE CS WD40 20 pdgawlasGsdDgtvr 35 p +++++++++Dg++ sp|Q99247|YO087_YEAST 35 PGKNYFLTSGRDGSII 50 66777788888***96 PP == domain 2 score: 8.9 bits; conditional E-value: 0.016 SSSE.EEEEEETTSSEE.EEEETTSEEEEE CS WD40 10 Hssv.tslafspdgawl.asGsdDgtvriW 37 H+++ +++ ++ +++l ++G+ D+++++W sp|Q99247|YO087_YEAST 161 HDGInNGIVVDEQNNFLfVTGGLDRKIKLW 190 76687888899999997469********** PP == domain 3 score: 10.1 bits; conditional E-value: 0.0069 EESS.SS...EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGH.ss...vtslafspdgawlasGsdDgtvriWd 38 +H ++ v+ l +++ ++++++s Dg + +Wd sp|Q99247|YO087_YEAST 264 QNAHrTNikvVRTL--DDSTRLISTSS-DGVINVWD 296 55787663433444..55555566667.*******9 PP >> sp|P53877|IPI3_YEAST Pre-rRNA-processing protein IPI3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.0 0.011 0.68 9 37 .. 137 166 .. 130 167 .. 0.89 2 ? 6.1 0.1 0.12 7.3 3 38 .] 181 225 .. 179 225 .. 0.67 3 ? 3.6 0.0 0.77 46 12 36 .. 346 370 .. 337 370 .. 0.81 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.011 SS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtvriW 37 +H +s+t ++ +g+++++++ D v iW sp|P53877|IPI3_YEAST 137 AHyQSITKIKSILNGKYIITSGNDSRVIIW 166 6888999999999*****99999******* PP == domain 2 score: 6.1 bits; conditional E-value: 0.12 EEEEEESS.SSEEEEE.EETTSSEEEEEET........TSEEEEEE CS WD40 3 clrtltGH.ssvtsla.fspdgawlasGsd........DgtvriWd 38 +l +l H +vt+++ s+ g++l s++d D t+r +d sp|P53877|IPI3_YEAST 181 PLCILHDHtLPVTDFQvSSSQGKFL-SCTDtklftvsqDATIRCYD 225 67788889767****9666666665.66644455555588888876 PP == domain 3 score: 3.6 bits; conditional E-value: 0.77 SEEEEEEETTSSEEEEEETTSEEEE CS WD40 12 svtslafspdgawlasGsdDgtvri 36 +v++l s dg++l+ G+ g+v i sp|P53877|IPI3_YEAST 346 NVSCLEISMDGTLLLIGDTEGKVSI 370 39************99987888765 PP >> sp|P47104|RAV1_YEAST Regulator of V-ATPase in vacuolar membrane protein 1 OS=Saccharomyces cerevisiae (strain ATCC 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.1 0.047 2.8 10 31 .. 98 119 .. 91 121 .. 0.80 2 ? 4.5 0.0 0.4 24 11 38 .] 145 173 .. 134 173 .. 0.82 3 ? 3.7 0.0 0.74 44 10 38 .] 191 230 .. 183 230 .. 0.62 4 ? 3.9 0.0 0.62 37 5 27 .. 380 403 .. 377 413 .. 0.75 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.047 S..SSEEEEEEETTSSEEEEEETT CS WD40 10 H..ssvtslafspdgawlasGsdD 31 H ++v++l++s+d+ + + Gs D sp|P47104|RAV1_YEAST 98 HddTPVNCLRWSSDNELAI-GS-D 119 75455************65.99.6 PP == domain 2 score: 4.5 bits; conditional E-value: 0.4 SSEEEEEEETTSSEEEE.EETTSEEEEEE CS WD40 11 ssvtslafspdgawlas.GsdDgtvriWd 38 ++v+ + s+d+++++s G +D++ ++W+ sp|P47104|RAV1_YEAST 145 KPVYNVIISQDSQLIVSiGKYDCNAKLWK 173 56899999******9853756*******6 PP == domain 3 score: 3.7 bits; conditional E-value: 0.74 S.SSEEEEEEETTSSE..........EEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgaw..........lasGsdDgtvriWd 38 H +++t++++ ++ + l + ++D+ +riW+ sp|P47104|RAV1_YEAST 191 HpKPITAMRWKKEPDQvsknntashaLYTLCEDKVLRIWS 230 88899999766666663333332332222234*******5 PP == domain 4 score: 3.9 bits; conditional E-value: 0.62 EEEESS.SSEEEEEEETTSSEEEE CS WD40 5 rtltGH.ssvtslafspdgawlas 27 +++tGH +sv l s+dg l++ sp|P47104|RAV1_YEAST 380 HKFTGHnKSVQKLVRSSDGEALLT 403 89****999*99986666665554 PP >> sp|Q02887|ATG21_YEAST Autophagy-related protein 21 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.1 6e-05 0.0036 9 34 .. 294 320 .. 288 321 .. 0.87 2 ? 1.3 0.0 4.3 2.6e+02 20 37 .. 463 478 .. 455 479 .. 0.78 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 6e-05 SS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 9 GH.ssvtslafspdgawlasGsdDgtv 34 H ++v +la+s+dg++la++sd+gt+ sp|Q02887|ATG21_YEAST 294 VHkGNVACLAVSHDGKLLATASDKGTI 320 58555*****************99998 PP == domain 2 score: 1.3 bits; conditional E-value: 4.3 TTSSEEEEEETTSEEEEE CS WD40 20 pdgawlasGsdDgtvriW 37 p++ ++ +sdDgt i+ sp|Q02887|ATG21_YEAST 463 PNQVYI--ASDDGTFSIY 478 666776..566***9998 PP >> sp|Q12363|WTM1_YEAST Transcriptional modulator WTM1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5592 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.2 9.7e-05 0.0058 10 38 .] 219 250 .. 212 250 .. 0.70 2 ? 5.5 0.1 0.2 12 18 38 .] 275 295 .. 256 295 .. 0.73 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 9.7e-05 S...SSE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H...ssv.tslafspdgawlasGsdDgtvriWd 38 H + v + ++f +++ + as+sdD+ +r+Wd sp|Q12363|WTM1_YEAST 219 HvpgTTVtHTVRFFDNHIF-ASCSDDNILRFWD 250 4322237557777777777.89**********9 PP == domain 2 score: 5.5 bits; conditional E-value: 0.2 EETTSSEEEEE.ETTSEEEEEE CS WD40 18 fspdgawlasG.sdDgtvriWd 38 + +++++++G s g +++Wd sp|Q12363|WTM1_YEAST 275 SQVSNNLFVTGfS-TGIIKLWD 295 444666689**55.*******9 PP >> sp|P38959|VPS41_YEAST Vacuolar protein sorting-associated protein 41 OS=Saccharomyces cerevisiae (strain ATCC 204508 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.1 2.3e-05 0.0014 2 36 .. 146 179 .. 145 179 .. 0.94 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 2.3e-05 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 2 qclrtltGH.ssvtslafspdgawlasGsdDgtvri 36 ++++t++ H ss+ ++ + dg+++a+Gs Dgtv i sp|P38959|VPS41_YEAST 146 EPIKTIKCHrSSILCI--NTDGKYFATGSIDGTVII 179 7899******99****..***************976 PP >> sp|Q12206|WTM2_YEAST Transcriptional modulator WTM2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5592 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.3 7.7e-05 0.0046 12 38 .] 247 273 .. 235 273 .. 0.71 2 ? 4.2 0.0 0.52 31 14 38 .] 293 318 .. 278 318 .. 0.62 3 ? 0.9 0.1 5.6 3.4e+02 10 38 .] 348 380 .. 341 380 .. 0.75 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 7.7e-05 SE.EEEEEETTSSEEEEEETTSEEEEEE CS WD40 12 sv.tslafspdgawlasGsdDgtvriWd 38 +v +s++f ++ + as+sdD+ +r+Wd sp|Q12206|WTM2_YEAST 247 NVaHSVRFFNNHLF-ASCSDDNILRFWD 273 37678877777777.89**********9 PP == domain 2 score: 4.2 bits; conditional E-value: 0.52 EEEE.EETTSSEEEEE.ETTSEEEEEE CS WD40 14 tsla.fspdgawlasG.sdDgtvriWd 38 ts++ + +++++G s g +++Wd sp|Q12206|WTM2_YEAST 293 TSFDsSQVTENLFVTGfS-TGVIKLWD 318 555433333445789*55.*******9 PP == domain 3 score: 0.9 bits; conditional E-value: 5.6 S.SS..EEEEEEETTSSE..EEEEETTSEEEEEE CS WD40 10 H.ss..vtslafspdgaw..lasGsdDgtvriWd 38 H ++ v ++ fs+ +a ++ G+ g+v+ Wd sp|Q12206|WTM2_YEAST 348 HsGGdsVVDILFSQTSATefVTVGG-TGNVYHWD 380 5311358899899999888677789.99999998 PP >> sp|P40960|PAC11_YEAST WD repeat-containing protein PAC11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.1 7.4e-05 0.0044 10 38 .] 433 466 .. 427 466 .. 0.85 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 7.4e-05 S.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS WD40 10 H.ssvtslafspdgaw....lasGsdDgtvriWd 38 H + vt+l f+ d a l+s+s D tvr+Wd sp|P40960|PAC11_YEAST 433 HsTRVTGLEFHWDDARrlmlLLSCSTDWTVRLWD 466 8555****998888889998789999*******9 PP >> sp|P53235|EIF2A_YEAST Eukaryotic translation initiation factor 2A OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.44 27 11 27 .. 72 88 .. 51 105 .. 0.71 2 ? 2.4 0.0 1.9 1.1e+02 17 28 .. 331 351 .. 278 363 .. 0.71 3 ? 9.0 0.1 0.015 0.92 3 37 .. 370 409 .. 368 410 .. 0.68 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.44 SSEEEEEEETTSSEEEE CS WD40 11 ssvtslafspdgawlas 27 s+v++l fsp g++l++ sp|P53235|EIF2A_YEAST 72 SDVYDLHFSPAGNYLST 88 3599**********965 PP == domain 2 score: 2.4 bits; conditional E-value: 1.9 E........EETTSSEEE.EE CS WD40 17 a........fspdgawla.sG 28 fsp+g++++ +G sp|P53235|EIF2A_YEAST 331 PqqakntmlFSPSGHYILiAG 351 333344444888888865255 PP == domain 3 score: 9.0 bits; conditional E-value: 0.015 EEEEEESSSSEEEEE.EETTSSEEEEEET......TSEEEEE CS WD40 3 clrtltGHssvtsla.fspdgawlasGsd......DgtvriW 37 c+ ++++ + ts++ +sp g ++++++ D+ v+iW sp|P53235|EIF2A_YEAST 370 CVSKFDATN--TSVCkWSPGGEFIMTATTsprlrvDNGVKIW 409 555555442..45556********98853344556******* PP >> sp|P32480|HIR2_YEAST Protein HIR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=HIR2 PE=1 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 7.5 4.5e+02 10 37 .. 11 37 .. 5 38 .. 0.65 2 ? 9.6 0.0 0.01 0.61 23 38 .] 291 307 .. 281 307 .. 0.81 3 ? 1.3 0.0 4 2.4e+02 23 37 .. 564 577 .. 545 578 .. 0.74 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 7.5 SSS.EEEEEEETTSSE.EEEEETTSEEEEE CS WD40 10 Hss.vtslafspdgaw.lasGsdDgtvriW 37 H+ v++l g++ +++Gs g+v+ W sp|P32480|HIR2_YEAST 11 HNEqVNAL--AALGPYiILAGS-GGHVMAW 37 63337777..3335552348**.****998 PP == domain 2 score: 9.6 bits; conditional E-value: 0.01 SEEE.EEETTSEEEEEE CS WD40 23 awla.sGsdDgtvriWd 38 +++a sGs Dgt+ +W+ sp|P32480|HIR2_YEAST 291 NLIAtSGSTDGTILVWN 307 567647899*******8 PP == domain 3 score: 1.3 bits; conditional E-value: 4 SEEEEEETTSEEEEE CS WD40 23 awlasGsdDgtvriW 37 w + +s+Dg+++i+ sp|P32480|HIR2_YEAST 564 FWSF-CSEDGSIYIY 577 4544.788*****98 PP >> sp|Q03774|TRM82_YEAST tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82 OS=Saccharomyces cerevisiae # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.74 44 16 38 .] 108 131 .. 96 131 .. 0.75 2 ? 3.9 0.1 0.63 38 9 36 .. 193 224 .. 185 224 .. 0.74 3 ! 9.7 1.0 0.0091 0.55 9 38 .] 239 268 .. 229 268 .. 0.85 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.74 EE.EETTSSEEEEEETTSEEEEEE CS WD40 16 la.fspdgawlasGsdDgtvriWd 38 l+ +s++++++a+++ D+++ ++d sp|Q03774|TRM82_YEAST 108 LRlTSDESRLIACADSDKSLLVFD 131 4546777888887755****9998 PP == domain 2 score: 3.9 bits; conditional E-value: 0.63 SS.SSEEEEE...EETTSSEEEEEETTSEEEE CS WD40 9 GH.ssvtsla...fspdgawlasGsdDgtvri 36 GH s t++ s+ +++++++++D +++i sp|Q03774|TRM82_YEAST 193 GHvSMLTDVHlikDSDGHQFIITSDRDEHIKI 224 78433566666658888888999999****98 PP == domain 3 score: 9.7 bits; conditional E-value: 0.0091 SSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 9 GHss.vtslafspdgawlasGsdDgtvriWd 38 GH++ v+s++ +d +l++G+ D ++ Wd sp|Q03774|TRM82_YEAST 239 GHKHfVSSICCGKDYLLLSAGG-DDKIFAWD 268 99666*************9***.88888887 PP >> sp|Q03010|UME1_YEAST Transcriptional regulatory protein UME1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.8 0.0 0.001 0.06 13 37 .. 238 261 .. 224 261 .. 0.77 2 ? 3.6 0.1 0.8 48 14 38 .] 282 307 .. 269 307 .. 0.77 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.001 EEEEEEETTSSEEEEEETTSEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriW 37 + ++f ++ + a++sdDg +r+W sp|Q03010|UME1_YEAST 238 IQEIKFLNNQIF-ATCSDDGIIRFW 261 556667777777.89********** PP == domain 2 score: 3.6 bits; conditional E-value: 0.8 EEEEEETTSSEE.EEEETTSEEEEEE CS WD40 14 tslafspdgawl.asGsdDgtvriWd 38 t++a sp + l ++G+ g +++Wd sp|Q03010|UME1_YEAST 282 TCFAASPFVDTLfMTGTSGGALKVWD 307 566656666665259*66*******9 PP >> sp|P11655|SEC12_YEAST Guanine nucleotide-exchange factor SEC12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.1 4.2 2.5e+02 13 29 .. 176 194 .. 167 235 .. 0.84 2 ! 10.5 0.0 0.0051 0.3 7 36 .. 304 335 .. 299 337 .. 0.79 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 4.2 EEEEEEETTSSEEE..EEE CS WD40 13 vtslafspdgawla..sGs 29 v +l fs dg+ +a +Gs sp|P11655|SEC12_YEAST 176 VKDLHFSTDGKVVAyiTGS 194 7889999999998655665 PP == domain 2 score: 10.5 bits; conditional E-value: 0.0051 EE.SS.SSEEEEEEETTSSEEEEEETTSEEEE CS WD40 7 lt.GH.ssvtslafspdgawlasGsdDgtvri 36 ++ +H + +t + spd++++as s +t++i sp|P11655|SEC12_YEAST 304 FKqAHsFAITEVTISPDSTYVASVSAANTIHI 335 54489555*************98887777776 PP >> sp|P38164|SEA4_YEAST SEH-associated protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 2.5 1.5e+02 5 38 .] 47 81 .. 44 81 .. 0.69 2 ? 8.3 0.0 0.025 1.5 14 38 .] 242 267 .. 229 267 .. 0.78 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 2.5 EEEESSSSEEEEEEETTSSEEE.EEETTSEEEEEE CS WD40 5 rtltGHssvtslafspdgawla.sGsdDgtvriWd 38 +t + +s+t+l++s + ++ G ++g +ri++ sp|P38164|SEA4_YEAST 47 HTVKDFGSITCLDYSESEIGMIgVGEKNGYLRIFN 81 55554456****88887777763345799999886 PP == domain 2 score: 8.3 bits; conditional E-value: 0.025 EEEEEETTSSEEEEE.ETTSEEEEEE CS WD40 14 tslafspdgawlasG.sdDgtvriWd 38 ++++ +p ++w +s +dDgt+ iWd sp|P38164|SEA4_YEAST 242 YDIKLNPFNDWQFSTyGDDGTLAIWD 267 688899*****5555588*******9 PP >> sp|P22219|VPS15_YEAST Serine/threonine-protein kinase VPS15 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.8 0.0 0.0041 0.24 18 38 .] 1089 1109 .. 1069 1109 .. 0.76 2 ? 0.8 0.4 6 3.6e+02 6 38 .] 1270 1306 .. 1266 1306 .. 0.66 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0041 EETTSSEEEEEETTSEEEEEE CS WD40 18 fspdgawlasGsdDgtvriWd 38 + + ++l++Gsd g ++iW+ sp|P22219|VPS15_YEAST 1089 SPGETPYLITGSDQGVIKIWN 1109 6677899*************8 PP == domain 2 score: 0.8 bits; conditional E-value: 6 EEESSSSEEEEE....EETTSSEEEEEETTSEEEEEE CS WD40 6 tltGHssvtsla....fspdgawlasGsdDgtvriWd 38 ++ H ++t++ + +++ ++ Gs + + iW+ sp|P22219|VPS15_YEAST 1270 SFGDHAPITHVEvcqfYGKNSVIVVGGSSKTFLTIWN 1306 5677877887776663555555555556699999997 PP >> sp|P48234|NOL10_YEAST Ribosome biogenesis protein ENP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.51 31 16 38 .] 62 85 .. 53 85 .. 0.88 2 ? 2.7 0.0 1.5 90 10 38 .] 185 208 .. 177 208 .. 0.77 3 ? 1.7 0.1 3.2 1.9e+02 25 38 .] 289 301 .. 268 301 .. 0.80 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.51 EEEETTSSE.EEEEETTSEEEEEE CS WD40 16 lafspdgaw.lasGsdDgtvriWd 38 +++s+dg++ +a+G++++ ++++d sp|P48234|NOL10_YEAST 62 IKVSRDGQYcMATGTYKPQIHVYD 85 779******5579999******98 PP == domain 2 score: 2.7 bits; conditional E-value: 1.5 S...SSEEEEEEETTSSEEEEEETTSEEEEEE CS WD40 10 H...ssvtslafspdgawlasGsdDgtvriWd 38 H + v++l la+G++ + v +Wd sp|P48234|NOL10_YEAST 185 HvsiNEVNGL--------LAAGTETNVVEFWD 208 5423347888........9****9*******9 PP == domain 3 score: 1.7 bits; conditional E-value: 3.2 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 +++++ ++ +iWd sp|P48234|NOL10_YEAST 289 IVTCD-KRIAKIWD 301 67888.*******9 PP >> sp|Q12038|SRO7_YEAST Lethal(2) giant larvae protein homolog SRO7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 5.5 3.3e+02 13 38 .] 161 186 .. 149 186 .. 0.81 2 ? 1.9 0.0 2.7 1.6e+02 14 38 .] 276 299 .. 265 299 .. 0.83 3 ? 4.1 0.0 0.55 33 25 38 .] 510 523 .. 502 523 .. 0.83 4 ? 0.2 0.0 9.2 5.5e+02 2 24 .. 672 690 .. 671 710 .. 0.65 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 5.5 EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 13 vtslafspdgawlasGsdDgtvriWd 38 +ts++++ + +w++ G +g+ ++d sp|Q12038|SRO7_YEAST 161 ITSIDTDASLDWMLIGLQNGSMIVYD 186 9***********99998888887776 PP == domain 2 score: 1.9 bits; conditional E-value: 2.7 EEEEEETTSSEEEEEETTSEEEEEE CS WD40 14 tslafspdgawlasGsdDgtvriWd 38 sl ++p++ +++ ++D+++ +Wd sp|Q12038|SRO7_YEAST 276 QSL-YHPNSLHIITIHEDNSLVFWD 299 555.89999999877*********9 PP == domain 3 score: 4.1 bits; conditional E-value: 0.55 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 +++G+ +g+vri+d sp|Q12038|SRO7_YEAST 510 FITGHSNGSVRIYD 523 468*88*******8 PP == domain 4 score: 0.2 bits; conditional E-value: 9.2 EEEEEEESS.SS.EEEEEEETTSSE CS WD40 2 qclrtltGH.ss.vtslafspdgaw 24 +++r+++G s vt++ + sp|Q12038|SRO7_YEAST 672 ENIREISGAqSAcVTCIE------F 690 5788999996447****4......4 PP >> sp|Q00772|SLT2_YEAST Mitogen-activated protein kinase SLT2/MPK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.0018 0.11 2 22 .. 74 99 .. 73 105 .. 0.83 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.0018 EEEEEEESSSSEEEEE.....EETTS CS WD40 2 qclrtltGHssvtsla.....fspdg 22 ++lr+++GH+++t+l f pdg sp|Q00772|SLT2_YEAST 74 KLLRHFRGHKNITCLYdmdivFYPDG 99 689******99****77777777776 PP >> sp|P50079|HSV2_YEAST SVP1-like protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=HSV2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.48 29 5 34 .. 218 248 .. 215 253 .. 0.81 2 ? 6.5 0.0 0.096 5.7 2 37 .. 247 296 .. 246 297 .. 0.72 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.48 EEEESS.SSEEEEEEETTSSEEEEEETTSEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtv 34 ++++H +++ ++ ++ g+++a++s gt+ sp|P50079|HSV2_YEAST 218 SIIKAHkNPIKLVRLNRQGTMVATCSVQGTL 248 67889*888866666999********88875 PP == domain 2 score: 6.5 bits; conditional E-value: 0.096 EEEEEEESSSS..............EEEEEEETTSSEEEEEETTSEEEEE CS WD40 2 qclrtltGHss..............vtslafspdgawlasGsdDgtvriW 37 +++r++++H++ ++ ++fsp+g+ la s ++t++i+ sp|P50079|HSV2_YEAST 247 TLIRIFSTHNGtlikefrrgvdkadIYEMSFSPNGSKLAVLSNKQTLHIF 296 578899999666866666666666677777*******9754768888775 PP >> sp|P38332|DPH7_YEAST Diphthine methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.45 27 13 37 .. 67 92 .. 56 93 .. 0.76 2 ? 1.4 0.0 3.7 2.2e+02 19 34 .. 209 224 .. 192 226 .. 0.83 3 ? 2.2 0.1 2.1 1.3e+02 13 35 .. 246 274 .. 236 275 .. 0.65 4 ? 2.2 0.2 2.2 1.3e+02 8 35 .. 356 383 .. 348 385 .. 0.56 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.45 EEEEEEETTSSEEE.EEETTSEEEEE CS WD40 13 vtslafspdgawla.sGsdDgtvriW 37 + +l+ sp + l+ +++ g++++W sp|P38332|DPH7_YEAST 67 ILDLKLSPFDDTLIcTAHSTGNIMLW 92 8899988888887636677******* PP == domain 2 score: 1.4 bits; conditional E-value: 3.7 ETTSSEEEEEETTSEE CS WD40 19 spdgawlasGsdDgtv 34 +p ++ +++G+dD + sp|P38332|DPH7_YEAST 209 QPFQDVVFTGGDDSRI 224 56667799***99887 PP == domain 3 score: 2.2 bits; conditional E-value: 2.1 EEEEE.....EETTSSE.EEEEETTSEEE CS WD40 13 vtsla.....fspdgaw.lasGsdDgtvr 35 v s++ f +++ +++Gs+D ++r sp|P38332|DPH7_YEAST 246 VVSIKcsqpnFRNNKPTsIITGSYDDNIR 274 555555555544444445779**999998 PP == domain 4 score: 2.2 bits; conditional E-value: 2.2 ESSSSEEEEEEETTSSEEEEEE.TTSEEE CS WD40 8 tGHssvtslafspdgawlasGs.dDgtvr 35 +GH+s + + +++++a++s +D+++ sp|P38332|DPH7_YEAST 356 KGHDSM-CYGGDWSNSLIATCSfYDNSLQ 383 477543.4423333444999975799876 PP >> sp|P40077|DSE1_YEAST Protein DSE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DSE1 PE=1 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.0 0.021 1.2 5 35 .. 125 173 .. 121 186 .. 0.75 2 ? 1.8 0.0 2.9 1.8e+02 7 38 .] 354 386 .. 348 386 .. 0.76 3 ? 2.5 0.0 1.8 1.1e+02 18 35 .. 419 436 .. 394 437 .. 0.68 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.021 EEEESS.SSEEEEE................EETTSSE.EEEEETTSEEE CS WD40 5 rtltGH.ssvtsla................fspdgaw.lasGsdDgtvr 35 +t+t +++t+++ +p+++ +++G+ Dg v sp|P40077|DSE1_YEAST 125 QTITVPgKPITCICllpmvdfppqifpssqINPNHNQlILTGHQDGIVN 173 5555555689999999999999998888884455554256999999886 PP == domain 2 score: 1.8 bits; conditional E-value: 2.9 EESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS WD40 7 ltGHss.vtslafspdgawlasGsdDgtvriWd 38 l + ++ + sl+f+ + l s++d g v Wd sp|P40077|DSE1_YEAST 354 LYAKKGyIESLKFNENTGALYSSDDQGFVICWD 386 54443349999999999999*999999999998 PP == domain 3 score: 2.5 bits; conditional E-value: 1.8 EETTSSEEEEEETTSEEE CS WD40 18 fspdgawlasGsdDgtvr 35 + + g+ ++sG+ D+++ sp|P40077|DSE1_YEAST 419 VFQCGNIIVSGMSDKNIC 436 567789999**66*9997 PP >> sp|P35184|SQT1_YEAST Ribosome assembly protein SQT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5592 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.3 0.02 1.2 7 37 .. 61 92 .. 55 93 .. 0.86 2 ? 3.8 0.1 0.66 39 5 35 .. 103 134 .. 100 136 .. 0.83 3 ? 2.4 0.1 1.9 1.1e+02 25 38 .] 221 234 .. 168 234 .. 0.80 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.02 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS WD40 7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 ++ H +sv ++ +p+ +++++G+ D+ ++W sp|P35184|SQT1_YEAST 61 FDKHtDSVFAIGHHPNLPLVCTGGGDNLAHLW 92 6679777****************88******9 PP == domain 2 score: 3.8 bits; conditional E-value: 0.66 EEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS WD40 5 rtltGH.ssvtslafspdgawlasGsdDgtvr 35 +tltG sv s++f ++g +l+++++ g+v sp|P35184|SQT1_YEAST 103 GTLTGYgESVISCSFTSEGGFLVTADMSGKVL 134 57888876788*************98888875 PP == domain 3 score: 2.4 bits; conditional E-value: 1.9 EEEEETTSEEEEEE CS WD40 25 lasGsdDgtvriWd 38 l+++s D t+ W+ sp|P35184|SQT1_YEAST 221 LVTCSLDSTIVAWN 234 689999****9997 PP >> sp|Q06214|JIP5_YEAST WD repeat-containing protein JIP5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 0.1 0.035 2.1 6 35 .. 124 154 .. 119 154 .. 0.77 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.035 EEESS.SSEEEEEEETTSSEEEE.EETTSEEE CS WD40 6 tltGH.ssvtslafspdgawlas.GsdDgtvr 35 + + H +sv++++f++ g+ ++s Gs D+ ++ sp|Q06214|JIP5_YEAST 124 KTKRHkGSVRAMCFDSKGDNIFSvGS-DNVLK 154 55679777************975267.99876 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (38 nodes) Target sequences: 6049 (2936363 residues searched) Passed MSV filter: 239 (0.0395107); expected 121.0 (0.02) Passed bias filter: 219 (0.0362043); expected 121.0 (0.02) Passed Vit filter: 115 (0.0190114); expected 6.0 (0.001) Passed Fwd filter: 101 (0.016697); expected 0.1 (1e-05) Initial search space (Z): 6049 [actual number of targets] Domain search space (domZ): 101 [number of targets reported over threshold] # CPU time: 0.09u 0.00s 00:00:00.09 Elapsed: 00:00:00.03 # Mc/sec: 3719.39 // [ok]