# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/zf-GRF.hmm.txt
# target sequence database:        proteomes/Drosophila_melanogaster.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       zf-GRF  [M=45]
Accession:   PF06839.12
Description: GRF zinc finger
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.6e-38  130.2  18.6    4.6e-21   74.3   2.1    3.0  3  sp|Q9NG98|TOP3A_DROME   DNA topoisomerase 3-alpha OS=Drosophi
  ------ inclusion threshold ------
       0.04   13.6   0.2      0.098   12.4   0.2    1.7  1  tr|A8DY89|A8DY89_DROME  Uncharacterized protein OS=Drosophila


Domain annotation for each sequence (and alignments):
>> sp|Q9NG98|TOP3A_DROME  DNA topoisomerase 3-alpha OS=Drosophila melanogaster OX=7227 GN=Top3alpha PE=2 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.4         2   1.4e+04      26      33 ..     656     663 ..     656     664 .. 0.79
   2 !   66.3   2.8   2.1e-22   1.4e-18       1      44 [.    1033    1075 ..    1033    1076 .. 0.97
   3 !   74.3   2.1   6.6e-25   4.6e-21       1      44 [.    1150    1192 ..    1150    1193 .. 0.95

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 2
                 zf-GRF  26 YkCpkgke 33 
                            ++Cpk++e
  sp|Q9NG98|TOP3A_DROME 656 FQCPKCNE 663
                            68999986 PP

  == domain 2  score: 66.3 bits;  conditional E-value: 2.1e-22
                 zf-GRF    1 plCk.cgrlavlltvrktgpNkGRkFYkCpkgkekqCgFFkWade 44  
                             +lC+ c+++a+++tvrk+gpN GR +YkCpk++e  C+FF+Wade
  sp|Q9NG98|TOP3A_DROME 1033 VLCTgCQQPARQNTVRKNGPNLGRLYYKCPKPDE--CNFFQWADE 1075
                             68*******************************9..********8 PP

  == domain 3  score: 74.3 bits;  conditional E-value: 6.6e-25
                 zf-GRF    1 plCkcgrlavlltvrktgpNkGRkFYkCpkgkekqCgFFkWade 44  
                             ++C+cg+la++ltvrk+gpN+GR FY+Cp++++ +CgFFkW de
  sp|Q9NG98|TOP3A_DROME 1150 VMCNCGQLASQLTVRKDGPNQGRPFYACPTREK-SCGFFKWGDE 1192
                             69*****************************95.9********8 PP

>> tr|A8DY89|A8DY89_DROME  Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG34220 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.2   1.4e-05     0.098       5      43 ..     668     706 ..     665     708 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.4e-05
                  zf-GRF   5 cgrlavlltvrktgpNkGRkFYkCpkgke..kqCgFFkWad 43 
                             c ++a   +v  + pN+ R +Y C +g+   ++C    W d
  tr|A8DY89|A8DY89_DROME 668 CAGRADGSIV--QDPNHCRRYYECRAGRRllRKCRAGLWYD 706
                             7788888999..59*************99887786666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (45 nodes)
Target sequences:                        13786  (7394964 residues searched)
Passed MSV filter:                       629  (0.045626); expected 275.7 (0.02)
Passed bias filter:                      290  (0.0210358); expected 275.7 (0.02)
Passed Vit filter:                        21  (0.00152328); expected 13.8 (0.001)
Passed Fwd filter:                         2  (0.000145075); expected 0.1 (1e-05)
Initial search space (Z):              13786  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.07u 0.00s 00:00:00.07 Elapsed: 00:00:00.05
# Mc/sec: 6655.47
//
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