# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/zf-GRF.hmm.txt
# target sequence database:        proteomes/Petromyzon_marinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       zf-GRF  [M=45]
Accession:   PF06839.12
Description: GRF zinc finger
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    6.2e-34  115.5   6.7    1.2e-17   63.3   0.7    3.0  2  tr|S4RC13|S4RC13_PETMA  DNA topoisomerase OS=Petromyzon marin
    1.7e-31  107.6  28.4    2.2e-18   65.7   1.5    4.6  5  tr|S4RD41|S4RD41_PETMA  Nei-like DNA glycosylase 3 OS=Petromy


Domain annotation for each sequence (and alignments):
>> tr|S4RC13|S4RC13_PETMA  DNA topoisomerase OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.3   0.8   1.2e-18   7.8e-15       2      44 ..     810     849 ..     809     850 .. 0.95
   2 !   63.3   0.7   1.8e-21   1.2e-17       1      42 [.     877     918 ..     877     922 .. 0.95

  Alignments for each domain:
  == domain 1  score: 54.3 bits;  conditional E-value: 1.2e-18
                  zf-GRF   2 lCkcgrlavlltvrktgpNkGRkFYkCpkgkekqCgFFkWade 44 
                              C+cg +a+lltv+k+g NkGR FYkC+      C+FF Wad+
  tr|S4RC13|S4RC13_PETMA 810 VCNCGIEATLLTVKKEGINKGRMFYKCSSSV---CNFFLWADQ 849
                             7***************************998...********7 PP

  == domain 2  score: 63.3 bits;  conditional E-value: 1.8e-21
                  zf-GRF   1 plCkcgrlavlltvrktgpNkGRkFYkCpkgkekqCgFFkWa 42 
                             ++C c ++av++t  k+gpNkGR+FY+C+k++++qCgFF W 
  tr|S4RC13|S4RC13_PETMA 877 VMCSCNNPAVMRTIVKDGPNKGRQFYTCSKPRDEQCGFFLWM 918
                             69***************************************6 PP

>> tr|S4RD41|S4RD41_PETMA  Nei-like DNA glycosylase 3 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.29     2e+03      25      32 ..      24      31 ..      21      41 .. 0.72
   2 !    5.9   2.6    0.0015        10       5      33 ..      46      73 ..      43      75 .. 0.73
   3 ?   -3.2   0.1       1.1   7.4e+03      12      22 ..     273     283 ..     270     283 .. 0.65
   4 !   52.7   1.4   3.7e-18   2.5e-14       3      43 ..     301     342 ..     299     344 .. 0.95
   5 !   65.7   1.5   3.2e-22   2.2e-18       1      43 [.     346     388 ..     346     390 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.29
                  zf-GRF 25 FYkCpkgk 32
                            FY+C k  
  tr|S4RD41|S4RD41_PETMA 24 FYQCRKTG 31
                            9***8765 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0015
                  zf-GRF  5 cgrlavlltvrktgpNkGRkFYkCpkgke 33
                            cg+  ++ +v + g+ +GR  Y Cp ++ 
  tr|S4RD41|S4RD41_PETMA 46 CGQCRTRVVVCRLGE-NGRMTYFCPHCQH 73
                            777555555555665.5*********986 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 1.1
                  zf-GRF  12 ltvrktgpNkG 22 
                             +t ++ g+N G
  tr|S4RD41|S4RD41_PETMA 273 RTPNNRGQNSG 283
                             56667777766 PP

  == domain 4  score: 52.7 bits;  conditional E-value: 3.7e-18
                  zf-GRF   3 Ck.cgrlavlltvrktgpNkGRkFYkCpkgkekqCgFFkWad 43 
                             C  + r++ l +v+k gpN+GR+F++C++++++qC  F+Wad
  tr|S4RD41|S4RD41_PETMA 301 CRgHDRPCALHVVQKAGPNRGRHFHACALPQKQQCQHFEWAD 342
                             99788************************************9 PP

  == domain 5  score: 65.7 bits;  conditional E-value: 3.2e-22
                  zf-GRF   1 plCkcgrlavlltvrktgpNkGRkFYkCpkgkekqCgFFkWad 43 
                             p C +g ++v++tv k gpN+GR+FY+C++g+++qC FF+Wad
  tr|S4RD41|S4RD41_PETMA 346 PECDHGLRCVMRTVLKLGPNNGRNFYACAQGRDRQCAFFQWAD 388
                             57****************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (45 nodes)
Target sequences:                        13539  (5048892 residues searched)
Passed MSV filter:                       561  (0.0414359); expected 270.8 (0.02)
Passed bias filter:                      259  (0.0191299); expected 270.8 (0.02)
Passed Vit filter:                        17  (0.00125563); expected 13.5 (0.001)
Passed Fwd filter:                         2  (0.000147721); expected 0.1 (1e-05)
Initial search space (Z):              13539  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.03
# Mc/sec: 7573.34
//
[ok]